The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
99
|
sequence length |
332
|
structure length |
332
|
Chain Sequence |
MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDLFHSSRPSPGTLKKAIALLQIPKEHSIPVFAIEGNHDRTQRGPSVLNLLEDFGLVYVIGMRKEKVENEYLTSERLGNGEYLVKGVYKDLEIHGMKYMSSAWFEANKEILKRLFRPTDNAILMLHQGVREVSEARGEDYFEIGLGDLPEGYLYYARGHIHKRYETSYSGSPVVYPGSLERWDFGDYEVRYEWDGIKFKERYGVNKGFYIVEDFKPRFVEIKVRPFIDVKIKGSEEEIRKAIKRLIPLIPKNAYVRLNIGWRKPFDLTEIKELLNVEYLKIDTWR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
pubmed doi rcsb |
| molecule tags |
Dna binding protein
|
| source organism |
Pyrococcus furiosus
|
| molecule keywords |
DNA double-strand break repair protein Mre11
|
| total genus |
99
|
| structure length |
332
|
| sequence length |
332
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2012-10-01 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00149 | Metallophos | Calcineurin-like phosphoesterase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Translation Initiation Factor IF3 | DNA double-strand break repair nuclease | ||
| Alpha Beta | 4-Layer Sandwich | Purple Acid Phosphatase; chain A, domain 2 | Purple Acid Phosphatase; chain A, domain 2 |
#chains in the Genus database with same CATH superfamily 2XMO A; 2Z06 A; 2QJC A; 4NZV A; 2BDX A; 5J28 A; 5JPF A; 1IT6 A; 4JA9 A; 5DNY A; 4YKE A; 1MF8 A; 4O5G A; 5C1V A; 2USH A; 4TUI A; 2Z1A A; 1Z2X A; 3EGH A; 3K7V C; 4DSY A; 2O8A A; 1S3L A; 2O8G A; 3JYF A; 3QFM A; 3RL3 A; 1KBP A; 4I5L C; 5F3W A; 1HPU A; 3IB8 A; 4FCX A; 3TGH A; 4HD0 A; 4ORB A; 4LAC C; 4UWQ A; 2QFR A; 2P6B A; 1AUI A; 3THO B; 2HYP A; 3AUZ A; 2QFP A; 4ORA A; 3QFN A; 4Q7F A; 5GTU A; 4ZX2 A; 3PSN A; 2WDD A; 3E7A A; 4OR9 A; 1QHW A; 4IL1 A; 3ICF A; 2WDF A; 3H69 A; 3KBP A; 4MP0 A; 3E7B A; 4O4K A; 4H2F A; 4V0V A; 2IE3 C; 2WDE A; 4G9J A; 3ZU0 A; 1XM7 A; 2JOG A; 5B8I A; 1Z2W A; 3DSD A; 1XZW A; 2YVT A; 1G5B A; 1JK7 A; 4KKZ A; 4UT3 A; 1T70 A; 2A22 A; 3FGA C; 4MOY A; 1TCO A; 2R17 A; 2WDC A; 2GJU A; 2Q8U A; 4FBK A; 4I5N C; 1WAO 1; 4O24 A; 4H2I A; 4UT2 A; 2KKN A; 1WAR A; 4V0X A; 3T1I A; 4XPN A; 5JPE A; 1OI8 A; 2BCD A; 2NYM C; 4UT3 B; 4M0V A; 3RL4 A; 5IOH A; 4KBP A; 2IE4 C; 2NPP C; 1QFC A; 4F0Z A; 2BQ8 X; 4FBW A; 4TUG A; 2NXF A; 1FJM A; 4JA7 A; 3THN A; 1S3N A; 3QFK A; 3RL5 A; 4FBQ A; 4J6O A; 1NNW A; 3H68 A; 1V73 A; 3H63 A; 1USH A; 5INB A; 3H61 A; 4IYP C; 2HYO A; 4LTY A; 5EQV A; 1UTE A; 2CV9 A; 3EGG A; 1S8E A; 4H2G A; 1U32 A; 3ZTV A; 1OID A; 1T71 A; 2DFJ A; 3IVD A; 1W24 A; 1SU1 A; 2Z72 A; 3DW8 C; 4H2B A; 3H62 B; 3V4Y A; 1S70 A; 4ORC A; 1OIE A; 2IAE C; 3C5W C; 5HPE A; 4B2O A; 3QG5 C; 1HP1 A; 2HY1 A; 4MOV A; 3CK2 A; 3HVQ A; 4LU9 A; 3H66 A; 5JJT A; 3P71 C; 3LL8 A; 1M63 A; 4H1Y P; 3QFO A; 4H1S A; 3IVE A; 4DT2 A; 4V0W A; 4WWL A; 1UF3 A; 3DSC A; 3RQZ A; 1S95 A; 2NYL C; 4DHL A; 3IB7 A; 1II7 A; 3H67 A; 1HO5 A; 3K7W C; 3N5U A; 3PSO A; 4O43 A; 3H64 A; 2ZBM A; 3C9F A; 3GVE A; 1S3M A; 3AV0 A; 2AHD A; 4ZVZ A; 3H60 A; #chains in the Genus database with same CATH topology 2XMO A; 1NJ1 A; 2Z06 A; 2QJC A; 3TTF A; 4K87 A; 4NZV A; 4K86 A; 2BDX A; 5J28 A; 5JPF A; 1IT6 A; 1PAV A; 4JA9 A; 5DNY A; 3D03 A; 4YKE A; 1MF8 A; 4O5G A; 5C1V A; 2USH A; 4TUI A; 2Z1A A; 1Z2X A; 3EGH A; 3K7V C; 4DSY A; 2YEQ A; 2O8A A; 1S3L A; 2O8G A; 3JYF A; 4NCX A; 2ZO9 B; 1KBP A; 3QFM A; 4I5L C; 3RL3 A; 4FCX A; 1HPU A; 3IB8 A; 4HVZ A; 3TGH A; 5F3W A; 4NZR M; 4TWA A; 3TSQ A; 4HD0 A; 3ZIH A; 1H0Y A; 4ORB A; 4LAC C; 4UWQ A; 2QFR A; 2P6B A; 2BKY X; 1AUI A; 3THO B; 2HYP A; 3AUZ A; 2LXR A; 1NH9 A; 2QFP A; 3U6Y A; 4ORA A; 3QFN A; 4Q7F A; 5GTU A; 4ZX2 A; 3PSN A; 2WDD A; 3E7A A; 4OR9 A; 1QHW A; 1XEZ A; 1NJ5 A; 4IL1 A; 2Y1B A; 3ZIE A; 4NZT M; 1H4S A; 3QKB A; 2WDF A; 3H69 A; 3E7B A; 3ICF A; 3KBP A; 4H2F A; 4MP0 A; 4O4K A; 4V0V A; 3TSP A; 2IE3 C; 2WDE A; 4G9J A; 1XM7 A; 2EH1 A; 2JOG A; 3ZU0 A; 1Z2W A; 5B8I A; 3DSD A; 2CRQ A; 4HVC A; 3TTC A; 3WBM A; 1G5B A; 1XZW A; 2YVT A; 1JK7 A; 4KKZ A; 1JDQ A; 1Y9X A; 4UT3 A; 1T70 A; 2A22 A; 3FGA C; 2DXN A; 4MOY A; 1TCO A; 2R17 A; 2WDC A; 1VR4 A; 2GJU A; 2Q8U A; 4FBK A; 4I5N C; 1WAO 1; 4O24 A; 4H2I A; 4UT2 A; 3E0J A; 2KKN A; 3TSU A; 1WAR A; 4V0X A; 3T1I A; 4XPN A; 1JO0 A; 5JPE A; 1OI8 A; 2BCD A; 2NYM C; 2P9B A; 1DCJ A; 2Q3V A; 4UT3 B; 4M0V A; 3RL4 A; 5IOH A; 4KBP A; 2IE4 C; 2NPP C; 1QFC A; 4F0Z A; 3FLO A; 2ZOA A; 1Y2I A; 4FBW A; 2BQ8 X; 4TUG A; 1NFH A; 2NXF A; 1LN4 A; 1NJ6 A; 1FJM A; 1RQ8 A; 1TIG A; 4JA7 A; 3THN A; 4YDQ A; 1S3N A; 3QFK A; 3RL5 A; 4FBQ A; 4J6O A; 1NNW A; 2EK0 A; 3H68 A; 2A2Y A; 1V73 A; 1USH A; 3H63 A; 3VTH A; 3H61 A; 5INB A; 2M71 A; 4K88 A; 2HYO A; 4IYP C; 1NJ2 A; 4Q15 A; 4LTY A; 5EQV A; 1UTE A; 2CV9 A; 2LN3 A; 3EGG A; 3IAL A; 1S8E A; 4H2G A; 2Z7C A; 1U32 A; 3ZTV A; 1OID A; 3TOE A; 1T71 A; 3HZ7 A; 2DFJ A; 3IVD A; 1W24 A; 2GTC A; 1SU1 A; 2Z72 A; 1H0X A; 2H9U A; 3IAB A; 3DW8 C; 3H62 B; 4H2B A; 3V4Y A; 3P04 A; 1NJ8 A; 1S70 A; 4ORC A; 1OIE A; 2IAE C; 3C5W C; 4EO0 A; 1NFJ A; 4B2O A; 5HPE A; 3QG5 C; 1JE3 A; 1VM0 A; 1HP1 A; 2HY1 A; 4MOV A; 3ZIG A; 3ZII A; 3CK2 A; 3HVQ A; 4LU9 A; 3IAB B; 4OLF A; 3H66 A; 5JJT A; 3P71 C; 3LL8 A; 1M63 A; 4H1Y P; 3TTD A; 3QFO A; 4H1S A; 3IVE A; 2DXL A; 4DT2 A; 3VTI A; 1H4T A; 1H4Q A; 3DSC A; 1HC7 A; 1UF3 A; 4V0W A; 4Z9E A; 4WWL A; 3RQZ A; 1S95 A; 1UDV A; 2NYL C; 2IFE A; 4DHL A; 3IB7 A; 1II7 A; 3H67 A; 1HO5 A; 3K7W C; 3N5U A; 3PSO A; 4O43 A; 3H64 A; 2ZBM A; 3C9F A; 3GVE A; 1S3M A; 3AV0 A; 2AHD A; 3LVK B; 4WI1 A; 4ZVZ A; 2L8Y A; 3H60 A; 3LVJ C; #chains in the Genus database with same CATH homology 2XMO A; 2Z06 A; 2QJC A; 4NZV A; 2BDX A; 5J28 A; 5JPF A; 1IT6 A; 4JA9 A; 5DNY A; 3D03 A; 4YKE A; 1MF8 A; 4O5G A; 5C1V A; 2USH A; 4TUI A; 2Z1A A; 1Z2X A; 3EGH A; 3K7V C; 4DSY A; 2YEQ A; 2O8A A; 1S3L A; 2O8G A; 3JYF A; 2ZO9 B; 3QFM A; 1KBP A; 4I5L C; 3RL3 A; 5F3W A; 1HPU A; 3IB8 A; 4FCX A; 3TGH A; 4HD0 A; 4ORB A; 4LAC C; 4UWQ A; 2QFR A; 2P6B A; 1AUI A; 2HYP A; 3AUZ A; 2QFP A; 4ORA A; 3QFN A; 4Q7F A; 5GTU A; 4ZX2 A; 3PSN A; 2WDD A; 3E7A A; 4OR9 A; 1QHW A; 4IL1 A; 3ICF A; 3H60 A; 2WDF A; 3H69 A; 3KBP A; 4MP0 A; 3E7B A; 4O4K A; 4H2F A; 4V0V A; 2IE3 C; 2WDE A; 4G9J A; 3ZU0 A; 1XM7 A; 2JOG A; 5B8I A; 1Z2W A; 3DSD A; 1XZW A; 2YVT A; 1G5B A; 1JK7 A; 4KKZ A; 4UT3 A; 1T70 A; 2A22 A; 3FGA C; 2DXN A; 4MOY A; 1TCO A; 2R17 A; 2WDC A; 2GJU A; 2Q8U A; 4FBK A; 4I5N C; 1WAO 1; 4O24 A; 4H2I A; 4UT2 A; 3E0J A; 2KKN A; 1WAR A; 4V0X A; 3T1I A; 4XPN A; 5JPE A; 1OI8 A; 2BCD A; 2NYM C; 4UT3 B; 4M0V A; 3RL4 A; 5IOH A; 4KBP A; 2IE4 C; 2NPP C; 1QFC A; 4F0Z A; 3FLO A; 2ZOA A; 2BQ8 X; 4FBW A; 4TUG A; 2NXF A; 1FJM A; 3THN A; 4JA7 A; 1S3N A; 3QFK A; 3RL5 A; 4FBQ A; 4J6O A; 1NNW A; 3H68 A; 1V73 A; 3H63 A; 1USH A; 5INB A; 3H61 A; 4IYP C; 2HYO A; 4LTY A; 5EQV A; 1UTE A; 2CV9 A; 3EGG A; 1S8E A; 4H2G A; 1U32 A; 3ZTV A; 1OID A; 1T71 A; 2DFJ A; 3IVD A; 1W24 A; 1SU1 A; 2Z72 A; 3DW8 C; 4H2B A; 3H62 B; 3V4Y A; 1S70 A; 4ORC A; 1OIE A; 2IAE C; 3C5W C; 5HPE A; 4B2O A; 3QG5 C; 1HP1 A; 2HY1 A; 4MOV A; 3CK2 A; 3HVQ A; 4LU9 A; 3H66 A; 5JJT A; 3P71 C; 3LL8 A; 1M63 A; 4H1Y P; 3QFO A; 4H1S A; 3IVE A; 2DXL A; 4DT2 A; 4V0W A; 4WWL A; 1UF3 A; 3DSC A; 3RQZ A; 1S95 A; 2NYL C; 4DHL A; 3IB7 A; 1II7 A; 3H67 A; 1HO5 A; 3K7W C; 3N5U A; 3PSO A; 4O43 A; 3H64 A; 2ZBM A; 3C9F A; 3GVE A; 1S3M A; 3AV0 A; 2AHD A; 4ZVZ A; 3THO B;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
