2RAIA

The px-bar membrane remodeling unit of sorting nexin 9
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
382
structure length
363
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 118
structure length 363
sequence length 382
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2raiA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2raiA02
4OXWA 4P2IA 2D1LA 4IKBB 1URUA 1X04A 2V0OA 2ETTA 2V14A 2Z0OA 4WPEA 1X03A 2ELBA 2CSKA 3P0CA 3ABHA 4AVMA 2RAKA 1I4DA 2Q13A 1ZWWA 1I4TA 1XTEA 4P2JA 2YPSA 2YKTA 3QWEA 3CAZA 4ON3A 4FZSA 4DYLA 4IKDA 3Q0KA 3FOGA 3PLTA 1WDZA 2REAA 2RAIA 4NSWA 3QE6A 3HPBA 4I1QA 3HPCX 3G9GA 3LUIA 3HAIA 4H8SA 2Q12A 2RAJA 2X3XA 3DYTA 1O7KA 2X3WA 1XTNA 1Y2OA 3I2WA 4PQOA 2I4KA 2FICA 2C08A 4AKVA 4ATMA 4NQIA 1OCUA 5C5BA 1KQ6A 2WWEA 2L73A 4AZ9A 2REDA 1OCSA 3OK8A 2V6VA 3HAJA 2Z0VA 5C5BB 1I49A 1I4LA 3QNIA 1KMDA 4DCNC 2EFLA 2EFKA 3Q84A 4PZGA 4BNEA 2DYBA 3SYVA 3IQ2A 3M3WA 3HAHA 2Z0NA 3SOGA 1GD5A 2X3VA 4WPCA 2CZOA 4PQPA 4BGJA 2D4CA 4IKBA 3LLLA 2AR5A 4HASA 2IWLX 1H6HA 3ACOA
chains in the Genus database with same CATH superfamily
4OXWA 1GN9A 4IKBB 3ERCC 4D8JA 4WPEA 4HY9A 1W9MA 2YL8A 4FZPA 4IM2A 4UDXX 3D50A 2WYHA 2YKTA 3QWEA 4EZQA 3RV1A 3BUBA 3T47A 2GAFD 3C7NA 1R33A 1OA0A 3ER9B 4G6QA 3LMFA 1HTYA 3LUIA 3I01A 3D2EA 2RAJA 3D4YA 2X3WA 4JLCA 4R5GA 3QNJA 5FLEX 3BVTA 4AZBA 2C08A 3BUDA 1SU7A 3VKHA 3RV0A 1KQ6A 2WWEA 2PY6A 2L73A 3BUIA 3CZSA 3OHXM 3BUPA 3T4AG 3UITA 2MI7A 4PZGA 4F01A 3O3MB 1PS3A 3M3WA 3EJUA 2NCZA 1GD5A 2X3VA 4IW0A 1JQKA 1TQTA 2CZOA 2LXYA 1E1DA 2ND1A 1MJGA 2F1BA 2OBMA 4R5JA 4EZSA 2D1LA 2YL5A 1OA1A 1E2UA 2V0OA 2ETTA 3I04A 2YIVX 1SU8A 2RAKA 2Z8YA 4KIKA 1O7DC 2YPSA 2YLAA 3D4ZA 5FIGA 1TQVA 2JNKA 4ON3A 4DYLA 3BLBA 3LVTA 3Q0KA 2WYIA 1DKYA 1WDZA 2REAA 1QWNA 4EZWA 3O3NB 3HPBA 3DX4A 4HR1A 4EZTA 1YWMA 3B53X 3T49A 4F00A 3DDFA 2JNSA 3OWGA 4R5LA 4JNFA 2ND0A 4HR1B 2QKWA 2F7OA 4AZIA 4AZ5A 3ZEDA 3I2WA 3CKDA 2FICA 4EZZA 1DKXA 2OW6A 1QX1A 2OO2A 3QA8A 3B52X 4PO2A 3GI7A 4H6IA 2YLLA 3OK8A 3HAJA 2Z0VA 3DPPA 3VEAA 1I4LA 1KMDA 2EFLA 3T46A 1U00A 3Q84A 4BNEA 2DYBA 3CV5A 3SOGA 2EWFA 1GNLA 4BGJA 4JN4A 2D4CA 3DX3A 3D52A 3ACOA 4E81A 2WINM 1URUA 2Z0OA 4JWDA 4AZCA 1X03A 3P0CA 3ABHA 4AVMA 3A98A 3BVWA 3DX1A 1ZYLA 2Q13A 3EJSA 3DX0A 1XTEA 4P2JA 3EJQA 3CAZA 3DPQA 4FZSA 3FOGA 2QFFA 1TQUA 3PLTA 3VEBA 3DDGA 1GNTA 2RAIA 3QE6A 4I1QA 3HPCX 1SU6A 1E9VA 4H8SA 3KAWA 2Q12A 2X3XA 4EZUA 3DX2A 4AZHA 3DYTA 4FM3A 1O7KA 2F1AA 1LQ7A 1Y2OA 4PQOA 4KIKB 2OW7A 2GF4A 3CVRA 1OCUA 4HYBA 3FD9A 4JWCA 5TKYA 3L3PA 4AZ9A 2YIBA 1OCSA 4IM3A 2V6VA 3BUQA 1I49A 1O7DB 4R5KA 1SUFA 2YIAA 3QNIA 2FYVA 4DCNC 2EFKA 2X5CA 2F18A 1QWUA 4IWOA 4M0MA 3IQ2A 2Z0NA 2YL9A 4UDYX 3L3OM 4WPCA 3T48A 4PQPA 1UPXA 3I39X 2OZNB 3ER8C 3BVUA 2OBLA 4HASA 3EJRA 2KHOA 4IWQA 2O0I1 4P2IA 3DPOA 1X04A 2EX3B 2V14A 3O3OB 4JL9A 3RPMA 2ELBA 4EZRA 2CSKA 5KBPA 1I4DA 3KDRA 1ZWWA 4R5IA 1I4TA 3F7WA 3EJPA 2YI9A 4EZYA 4FZOA 4EZVA 2ZXQA 4IKDA 4H6HA 2PMRA 2YL6A 3CZNA 2GA9D 2RT6A 4NSWA 4EZXA 2F7RA 3G9GA 3HAIA 4IWPA 1TQSA 2ALWA 4AZCB 4AZGA 1TQWA 1R34A 3D51A 1DKZA 3KAVA 1XTNA 2I4KA 4B9QA 2YI8A 4JNEA 4AKVA 4ATMA 4NQIA 2QXLA 2F7PA 5C5BA 1HXKA 2REDA 5E84A 3D2FA 2LM0A 4EZPA 2F7QA 5C5BB 3BVVA 3BVXA 1R5EA 4E3CA 4EZOA 3SYVA 4EZNA 3HAHA 2N3KA 4AZ6A 4JWIA 4NPHA 4JWEA 3B51X 1OAOA 3EJTA 4IKBA 4AZ7A 3LLLA 2AR5A 1HWWA 2IWLX 1H6HA 4IM0A
chains in the Genus database with same CATH topology
4OXWA 4P2IA 2D1LA 4IKBB 1URUA 1X04A 2V0OA 2ETTA 2V14A 2Z0OA 4WPEA 1X03A 2ELBA 2CSKA 3P0CA 3ABHA 4AVMA 2RAKA 1I4DA 2Q13A 1ZWWA 1I4TA 1XTEA 4P2JA 2YPSA 2YKTA 3QWEA 3CAZA 4ON3A 4FZSA 4DYLA 4IKDA 3Q0KA 3FOGA 3PLTA 1WDZA 2REAA 2RAIA 4NSWA 3QE6A 3HPBA 4I1QA 3HPCX 3G9GA 3LUIA 3HAIA 4H8SA 2Q12A 2RAJA 2X3XA 3DYTA 1O7KA 2X3WA 1XTNA 1Y2OA 3I2WA 4PQOA 2I4KA 2FICA 2C08A 4AKVA 4ATMA 4NQIA 1OCUA 5C5BA 1KQ6A 2WWEA 2L73A 4AZ9A 2REDA 1OCSA 3OK8A 2V6VA 3HAJA 2Z0VA 5C5BB 1I49A 1I4LA 3QNIA 1KMDA 4DCNC 2EFLA 2EFKA 3Q84A 4PZGA 4BNEA 2DYBA 3SYVA 3IQ2A 3M3WA 3HAHA 2Z0NA 3SOGA 1GD5A 2X3VA 4WPCA 2CZOA 4PQPA 4BGJA 2D4CA 4IKBA 3LLLA 2AR5A 4HASA 2IWLX 1H6HA 3ACOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OXW A;  4P2I A;  2D1L A;  4IKB B;  1URU A;  1X04 A;  2V0O A;  2ETT A;  2V14 A;  2Z0O A;  4WPE A;  1X03 A;  2ELB A;  2CSK A;  3P0C A;  3ABH A;  4AVM A;  2RAK A;  1I4D A;  2Q13 A;  1ZWW A;  1I4T A;  1XTE A;  4P2J A;  2YPS A;  2YKT A;  3QWE A;  3CAZ A;  4ON3 A;  4FZS A;  4DYL A;  4IKD A;  3Q0K A;  3FOG A;  3PLT A;  1WDZ A;  2REA A;  2RAI A;  4NSW A;  3QE6 A;  3HPB A;  4I1Q A;  3HPC X;  3G9G A;  3LUI A;  3HAI A;  4H8S A;  2Q12 A;  2RAJ A;  2X3X A;  3DYT A;  1O7K A;  2X3W A;  1XTN A;  1Y2O A;  3I2W A;  4PQO A;  2I4K A;  2FIC A;  2C08 A;  4AKV A;  4ATM A;  4NQI A;  1OCU A;  5C5B A;  1KQ6 A;  2WWE A;  2L73 A;  4AZ9 A;  2RED A;  1OCS A;  3OK8 A;  2V6V A;  3HAJ A;  2Z0V A;  5C5B B;  1I49 A;  1I4L A;  3QNI A;  1KMD A;  4DCN C;  2EFL A;  2EFK A;  3Q84 A;  4PZG A;  4BNE A;  2DYB A;  3SYV A;  3IQ2 A;  3M3W A;  3HAH A;  2Z0N A;  3SOG A;  1GD5 A;  2X3V A;  4WPC A;  2CZO A;  4PQP A;  4BGJ A;  2D4C A;  4IKB A;  3LLL A;  2AR5 A;  4HAS A;  2IWL X;  1H6H A;  3ACO A; 
#chains in the Genus database with same CATH topology
 4OXW A;  1GN9 A;  4IKB B;  3ERC C;  4D8J A;  4WPE A;  4HY9 A;  1W9M A;  2YL8 A;  4FZP A;  4IM2 A;  4UDX X;  3D50 A;  2WYH A;  2YKT A;  3QWE A;  4EZQ A;  3RV1 A;  3BUB A;  3T47 A;  2GAF D;  3C7N A;  1R33 A;  1OA0 A;  3ER9 B;  4G6Q A;  3LMF A;  1HTY A;  3LUI A;  3I01 A;  3D2E A;  2RAJ A;  3D4Y A;  2X3W A;  4JLC A;  4R5G A;  3QNJ A;  5FLE X;  3BVT A;  4AZB A;  2C08 A;  3BUD A;  1SU7 A;  3VKH A;  3RV0 A;  1KQ6 A;  2WWE A;  2PY6 A;  2L73 A;  3BUI A;  3CZS A;  3OHX M;  3BUP A;  3T4A G;  3UIT A;  2MI7 A;  4PZG A;  4F01 A;  3O3M B;  1PS3 A;  3M3W A;  3EJU A;  2NCZ A;  1GD5 A;  2X3V A;  4IW0 A;  1JQK A;  1TQT A;  2CZO A;  2LXY A;  1E1D A;  2ND1 A;  1MJG A;  2F1B A;  2OBM A;  4R5J A;  4EZS A;  2D1L A;  2YL5 A;  1OA1 A;  1E2U A;  2V0O A;  2ETT A;  3I04 A;  2YIV X;  1SU8 A;  2RAK A;  2Z8Y A;  4KIK A;  1O7D C;  2YPS A;  2YLA A;  3D4Z A;  5FIG A;  1TQV A;  2JNK A;  4ON3 A;  4DYL A;  3BLB A;  3LVT A;  3Q0K A;  2WYI A;  1DKY A;  1WDZ A;  2REA A;  1QWN A;  4EZW A;  3O3N B;  3HPB A;  3DX4 A;  4HR1 A;  4EZT A;  1YWM A;  3B53 X;  3T49 A;  4F00 A;  3DDF A;  2JNS A;  3OWG A;  4R5L A;  4JNF A;  2ND0 A;  4HR1 B;  2QKW A;  2F7O A;  4AZI A;  4AZ5 A;  3ZED A;  3I2W A;  3CKD A;  2FIC A;  4EZZ A;  1DKX A;  2OW6 A;  1QX1 A;  2OO2 A;  3QA8 A;  3B52 X;  4PO2 A;  3GI7 A;  4H6I A;  2YLL A;  3OK8 A;  3HAJ A;  2Z0V A;  3DPP A;  3VEA A;  1I4L A;  1KMD A;  2EFL A;  3T46 A;  1U00 A;  3Q84 A;  4BNE A;  2DYB A;  3CV5 A;  3SOG A;  2EWF A;  1GNL A;  4BGJ A;  4JN4 A;  2D4C A;  3DX3 A;  3D52 A;  3ACO A;  4E81 A;  2WIN M;  1URU A;  2Z0O A;  4JWD A;  4AZC A;  1X03 A;  3P0C A;  3ABH A;  4AVM A;  3A98 A;  3BVW A;  3DX1 A;  1ZYL A;  2Q13 A;  3EJS A;  3DX0 A;  1XTE A;  4P2J A;  3EJQ A;  3CAZ A;  3DPQ A;  4FZS A;  3FOG A;  2QFF A;  1TQU A;  3PLT A;  3VEB A;  3DDG A;  1GNT A;  2RAI A;  3QE6 A;  4I1Q A;  3HPC X;  1SU6 A;  1E9V A;  4H8S A;  3KAW A;  2Q12 A;  2X3X A;  4EZU A;  3DX2 A;  4AZH A;  3DYT A;  4FM3 A;  1O7K A;  2F1A A;  1LQ7 A;  1Y2O A;  4PQO A;  4KIK B;  2OW7 A;  2GF4 A;  3CVR A;  1OCU A;  4HYB A;  3FD9 A;  4JWC A;  5TKY A;  3L3P A;  4AZ9 A;  2YIB A;  1OCS A;  4IM3 A;  2V6V A;  3BUQ A;  1I49 A;  1O7D B;  4R5K A;  1SUF A;  2YIA A;  3QNI A;  2FYV A;  4DCN C;  2EFK A;  2X5C A;  2F18 A;  1QWU A;  4IWO A;  4M0M A;  3IQ2 A;  2Z0N A;  2YL9 A;  4UDY X;  3L3O M;  4WPC A;  3T48 A;  4PQP A;  1UPX A;  3I39 X;  2OZN B;  3ER8 C;  3BVU A;  2OBL A;  4HAS A;  3EJR A;  2KHO A;  4IWQ A;  2O0I 1;  4P2I A;  3DPO A;  1X04 A;  2EX3 B;  2V14 A;  3O3O B;  4JL9 A;  3RPM A;  2ELB A;  4EZR A;  2CSK A;  5KBP A;  1I4D A;  3KDR A;  1ZWW A;  4R5I A;  1I4T A;  3F7W A;  3EJP A;  2YI9 A;  4EZY A;  4FZO A;  4EZV A;  2ZXQ A;  4IKD A;  4H6H A;  2PMR A;  2YL6 A;  3CZN A;  2GA9 D;  2RT6 A;  4NSW A;  4EZX A;  2F7R A;  3G9G A;  3HAI A;  4IWP A;  1TQS A;  2ALW A;  4AZC B;  4AZG A;  1TQW A;  1R34 A;  3D51 A;  1DKZ A;  3KAV A;  1XTN A;  2I4K A;  4B9Q A;  2YI8 A;  4JNE A;  4AKV A;  4ATM A;  4NQI A;  2QXL A;  2F7P A;  5C5B A;  1HXK A;  2RED A;  5E84 A;  3D2F A;  2LM0 A;  4EZP A;  2F7Q A;  5C5B B;  3BVV A;  3BVX A;  1R5E A;  4E3C A;  4EZO A;  3SYV A;  4EZN A;  3HAH A;  2N3K A;  4AZ6 A;  4JWI A;  4NPH A;  4JWE A;  3B51 X;  1OAO A;  3EJT A;  4IKB A;  4AZ7 A;  3LLL A;  2AR5 A;  1HWW A;  2IWL X;  1H6H A;  4IM0 A; 
#chains in the Genus database with same CATH homology
 4OXW A;  4P2I A;  2D1L A;  4IKB B;  1URU A;  1X04 A;  2V0O A;  2ETT A;  2V14 A;  2Z0O A;  4WPE A;  1X03 A;  2ELB A;  2CSK A;  3P0C A;  3ABH A;  4AVM A;  2RAK A;  1I4D A;  2Q13 A;  1ZWW A;  1I4T A;  1XTE A;  4P2J A;  2YPS A;  2YKT A;  3QWE A;  3CAZ A;  4ON3 A;  4FZS A;  4DYL A;  4IKD A;  3Q0K A;  3FOG A;  3PLT A;  1WDZ A;  2REA A;  2RAI A;  4NSW A;  3QE6 A;  3HPB A;  4I1Q A;  3HPC X;  3G9G A;  3LUI A;  3HAI A;  4H8S A;  2Q12 A;  2RAJ A;  2X3X A;  3DYT A;  1O7K A;  2X3W A;  1XTN A;  1Y2O A;  3I2W A;  4PQO A;  2I4K A;  2FIC A;  2C08 A;  4AKV A;  4ATM A;  4NQI A;  1OCU A;  5C5B A;  1KQ6 A;  2WWE A;  2L73 A;  4AZ9 A;  2RED A;  1OCS A;  3OK8 A;  2V6V A;  3HAJ A;  2Z0V A;  5C5B B;  1I49 A;  1I4L A;  3QNI A;  1KMD A;  4DCN C;  2EFL A;  2EFK A;  3Q84 A;  4PZG A;  4BNE A;  2DYB A;  3SYV A;  3IQ2 A;  3M3W A;  3HAH A;  2Z0N A;  3SOG A;  1GD5 A;  2X3V A;  4WPC A;  2CZO A;  4PQP A;  4BGJ A;  2D4C A;  4IKB A;  3LLL A;  2AR5 A;  4HAS A;  2IWL X;  1H6H A;  3ACO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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