2RAJA

So4 bound px-bar membrane remodeling unit of sorting nexin 9
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
382
structure length
382
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 144
structure length 382
sequence length 382
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2rajA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2rajA02
2C08A 3P0CA 3PLTA 4AVMA 3HAHA 4PZGA 1O7KA 2RAJA 4HASA 1XTEA 2ETTA 2REAA 4DYLA 4FZSA 2Z0VA 3FOGA 2RAKA 2REDA 2EFLA 4WPEA 4BNEA 4WPCA 2D4CA 2CSKA 3QE6A 1I4LA 4NSWA 2YKTA 2I4KA 3CAZA 3M3WA 3OK8A 2X3XA 1I4DA 4P2IA 3Q84A 1KQ6A 2DYBA 3HAIA 2Z0OA 4PQOA 4NQIA 4BGJA 2Z0NA 3ABHA 1GD5A 3I2WA 4OXWA 5C5BA 3HAJA 2FICA 3ACOA 4ATMA 1OCSA 3SOGA 1X03A 2CZOA 3LLLA 2X3WA 4AZ9A 2AR5A 1ZWWA 1X04A 1I4TA 4ON3A 2Q12A 2ELBA 4H8SA 5C5BB 3QWEA 1H6HA 3Q0KA 4IKBA 3SYVA 1XTNA 3G9GA 2V0OA 2IWLX 2EFKA 2Q13A 4AKVA 2D1LA 4PQPA 1URUA 2YPSA 1Y2OA 3HPBA 1I49A 2V14A 3IQ2A 2RAIA 3DYTA 2WWEA 2V6VA 3LUIA 4I1QA 4P2JA 4IKBB 2L73A 1KMDA 1WDZA 4DCNC 4IKDA 2X3VA 3HPCX 1OCUA 3QNIA
chains in the Genus database with same CATH superfamily
1QX1A 4FZOA 1YWMA 3BVUA 4HASA 4IM0A 2F7QA 4DYLA 4FZSA 1TQWA 5FLEX 3DX0A 1R33A 4BNEA 2D4CA 4R5JA 2PY6A 3CKDA 1ZYLA 4NSWA 4EZZA 3BVVA 2I4KA 2QFFA 2X3XA 3KAWA 1OA1A 4HY9A 3DPOA 1OA0A 2DYBA 4IM3A 3HAIA 2OW7A 2Z0OA 4AZ5A 4PQOA 4F00A 2F1BA 2LM0A 4BGJA 3I2WA 2OO2A 4E3CA 1TQTA 4EZRA 3ACOA 4EZNA 2GAFD 3ZEDA 3VKHA 3DPQA 4IW0A 4ON3A 4EZOA 3L3PA 2ND0A 3LVTA 1HWWA 2Q12A 4EZSA 1H6HA 3T47A 4AZBA 3Q0KA 3G9GA 4NPHA 4AKVA 3DX3A 3LMFA 3VEBA 3D52A 3RPMA 3RV0A 5E84A 2RT6A 5TKYA 3DYTA 2EX3B 2ALWA 2N3KA 2YLAA 3EJQA 3BLBA 3D2EA 2LXYA 2QXLA 4DCNC 1TQSA 4KIKA 3CVRA 1OCUA 3QNIA 2C08A 3EJTA 4AZCB 3DPPA 3HAHA 3CZSA 4H6IA 3GI7A 1SUFA 3A98A 4AZIA 2NCZA 4EZYA 1DKXA 3FOGA 3CZNA 3ER8C 1E1DA 4WPEA 1TQUA 3QA8A 1QWNA 2JNKA 2O0I1 2ZXQA 4H6HA 1SU6A 2YKTA 3CAZA 3T4AG 3OK8A 4P2IA 4EZPA 4FZPA 4F01A 4JN4A 2GA9D 3BUQA 4E81A 3ABHA 2YIBA 4OXWA 1SU8A 3VEAA 3SOGA 3DDFA 3LLLA 4G6QA 3UITA 4JL9A 3D4YA 2YL6A 3I39X 3BVWA 4EZWA 4R5KA 1I4TA 4EZXA 4H8SA 3EJRA 3ER9B 2V0OA 3B52X 4EZTA 3F7WA 4AZ6A 4IWQA 2YPSA 1O7DB 3HPBA 4EZUA 1I49A 2F18A 3IQ2A 4EZQA 3ERCC 1TQVA 1U00A 4I1QA 3BUIA 3BVXA 2L73A 1QWUA 4JWIA 3CV5A 3I04A 1R34A 3T48A 4IKDA 3D2FA 2F7OA 2YIAA 2Z8YA 3P0CA 3PLTA 1PS3A 4AVMA 2RAJA 3O3NB 3OHXM 2ETTA 2PMRA 2YI9A 4KIKB 2WINM 3QNJA 2EFLA 3RV1A 4AZGA 2OZNB 3EJUA 4WPCA 2CSKA 5FIGA 3BUDA 4HYBA 3T46A 3D4ZA 3Q84A 1GNTA 3D51A 4R5GA 2KHOA 4JWCA 1DKZA 2YL5A 2X5CA 4AZHA 5C5BA 4IWPA 4IWOA 1UPXA 1W9MA 3KDRA 3T49A 4ATMA 1DKYA 1OCSA 4HR1A 2CZOA 3OWGA 3BUBA 3L3OM 4R5LA 2WYIA 3C7NA 4JNEA 2F7RA 3FD9A 4AZCA 3EJSA 3B51X 1SU7A 1E9VA 2YIVX 4JWDA 3I01A 4IKBA 3SYVA 1O7DC 2EFKA 2Q13A 4PQPA 2D1LA 4JWEA 2WWEA 4B9QA 1KMDA 1OAOA 2OBLA 4R5IA 1WDZA 1E2UA 2X3VA 3O3OB 4JNFA 1LQ7A 2YLLA 3O3MB 4PZGA 1O7KA 3KAVA 1XTEA 2REAA 4EZVA 4FM3A 2Z0VA 2RAKA 2REDA 2QKWA 1GN9A 3QE6A 1I4LA 1JQKA 4UDYX 2OW6A 3M3WA 1HTYA 1I4DA 2ND1A 3DX2A 2F1AA 1KQ6A 1HXKA 5KBPA 2MI7A 3BUPA 4NQIA 2YI8A 4D8JA 3DDGA 2OBMA 2Z0NA 1GD5A 2GF4A 3DX4A 2YL8A 1MJGA 4UDXX 3HAJA 1GNLA 1R5EA 2FICA 1X03A 2X3WA 4AZ9A 2AR5A 4IM2A 1ZWWA 1X04A 3EJPA 2ELBA 5C5BB 4M0MA 4JLCA 3QWEA 3DX1A 4HR1B 1XTNA 2WYHA 2IWLX 4PO2A 2YL9A 4AZ7A 3D50A 1URUA 1Y2OA 3BVTA 2V14A 3B53X 2RAIA 2V6VA 3LUIA 4P2JA 4IKBB 2F7PA 2FYVA 2EWFA 3HPCX 2JNSA
chains in the Genus database with same CATH topology
2C08A 3P0CA 3PLTA 4AVMA 3HAHA 4PZGA 1O7KA 2RAJA 4HASA 1XTEA 2ETTA 2REAA 4DYLA 4FZSA 2Z0VA 3FOGA 2RAKA 2REDA 2EFLA 4WPEA 4BNEA 4WPCA 2D4CA 2CSKA 3QE6A 1I4LA 4NSWA 2YKTA 2I4KA 3CAZA 3M3WA 3OK8A 2X3XA 1I4DA 4P2IA 3Q84A 1KQ6A 2DYBA 3HAIA 2Z0OA 4PQOA 4NQIA 4BGJA 2Z0NA 3ABHA 1GD5A 3I2WA 4OXWA 5C5BA 3HAJA 2FICA 3ACOA 4ATMA 1OCSA 3SOGA 1X03A 2CZOA 3LLLA 2X3WA 4AZ9A 2AR5A 1ZWWA 1X04A 1I4TA 4ON3A 2Q12A 2ELBA 4H8SA 5C5BB 3QWEA 1H6HA 3Q0KA 4IKBA 3SYVA 1XTNA 3G9GA 2V0OA 2IWLX 2EFKA 2Q13A 4AKVA 2D1LA 4PQPA 1URUA 2YPSA 1Y2OA 3HPBA 1I49A 2V14A 3IQ2A 2RAIA 3DYTA 2WWEA 2V6VA 3LUIA 4I1QA 4P2JA 4IKBB 2L73A 1KMDA 1WDZA 4DCNC 4IKDA 2X3VA 3HPCX 1OCUA 3QNIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C08 A;  3P0C A;  3PLT A;  4AVM A;  3HAH A;  4PZG A;  1O7K A;  2RAJ A;  4HAS A;  1XTE A;  2ETT A;  2REA A;  4DYL A;  4FZS A;  2Z0V A;  3FOG A;  2RAK A;  2RED A;  2EFL A;  4WPE A;  4BNE A;  4WPC A;  2D4C A;  2CSK A;  3QE6 A;  1I4L A;  4NSW A;  2YKT A;  2I4K A;  3CAZ A;  3M3W A;  3OK8 A;  2X3X A;  1I4D A;  4P2I A;  3Q84 A;  1KQ6 A;  2DYB A;  3HAI A;  2Z0O A;  4PQO A;  4NQI A;  4BGJ A;  2Z0N A;  3ABH A;  1GD5 A;  3I2W A;  4OXW A;  5C5B A;  3HAJ A;  2FIC A;  3ACO A;  4ATM A;  1OCS A;  3SOG A;  1X03 A;  2CZO A;  3LLL A;  2X3W A;  4AZ9 A;  2AR5 A;  1ZWW A;  1X04 A;  1I4T A;  4ON3 A;  2Q12 A;  2ELB A;  4H8S A;  5C5B B;  3QWE A;  1H6H A;  3Q0K A;  4IKB A;  3SYV A;  1XTN A;  3G9G A;  2V0O A;  2IWL X;  2EFK A;  2Q13 A;  4AKV A;  2D1L A;  4PQP A;  1URU A;  2YPS A;  1Y2O A;  3HPB A;  1I49 A;  2V14 A;  3IQ2 A;  2RAI A;  3DYT A;  2WWE A;  2V6V A;  3LUI A;  4I1Q A;  4P2J A;  4IKB B;  2L73 A;  1KMD A;  1WDZ A;  4DCN C;  4IKD A;  2X3V A;  3HPC X;  1OCU A;  3QNI A; 
#chains in the Genus database with same CATH topology
 1QX1 A;  4FZO A;  1YWM A;  3BVU A;  4HAS A;  4IM0 A;  2F7Q A;  4DYL A;  4FZS A;  1TQW A;  5FLE X;  3DX0 A;  1R33 A;  4BNE A;  2D4C A;  4R5J A;  2PY6 A;  3CKD A;  1ZYL A;  4NSW A;  4EZZ A;  3BVV A;  2I4K A;  2QFF A;  2X3X A;  3KAW A;  1OA1 A;  4HY9 A;  3DPO A;  1OA0 A;  2DYB A;  4IM3 A;  3HAI A;  2OW7 A;  2Z0O A;  4AZ5 A;  4PQO A;  4F00 A;  2F1B A;  2LM0 A;  4BGJ A;  3I2W A;  2OO2 A;  4E3C A;  1TQT A;  4EZR A;  3ACO A;  4EZN A;  2GAF D;  3ZED A;  3VKH A;  3DPQ A;  4IW0 A;  4ON3 A;  4EZO A;  3L3P A;  2ND0 A;  3LVT A;  1HWW A;  2Q12 A;  4EZS A;  1H6H A;  3T47 A;  4AZB A;  3Q0K A;  3G9G A;  4NPH A;  4AKV A;  3DX3 A;  3LMF A;  3VEB A;  3D52 A;  3RPM A;  3RV0 A;  5E84 A;  2RT6 A;  5TKY A;  3DYT A;  2EX3 B;  2ALW A;  2N3K A;  2YLA A;  3EJQ A;  3BLB A;  3D2E A;  2LXY A;  2QXL A;  4DCN C;  1TQS A;  4KIK A;  3CVR A;  1OCU A;  3QNI A;  2C08 A;  3EJT A;  4AZC B;  3DPP A;  3HAH A;  3CZS A;  4H6I A;  3GI7 A;  1SUF A;  3A98 A;  4AZI A;  2NCZ A;  4EZY A;  1DKX A;  3FOG A;  3CZN A;  3ER8 C;  1E1D A;  4WPE A;  1TQU A;  3QA8 A;  1QWN A;  2JNK A;  2O0I 1;  2ZXQ A;  4H6H A;  1SU6 A;  2YKT A;  3CAZ A;  3T4A G;  3OK8 A;  4P2I A;  4EZP A;  4FZP A;  4F01 A;  4JN4 A;  2GA9 D;  3BUQ A;  4E81 A;  3ABH A;  2YIB A;  4OXW A;  1SU8 A;  3VEA A;  3SOG A;  3DDF A;  3LLL A;  4G6Q A;  3UIT A;  4JL9 A;  3D4Y A;  2YL6 A;  3I39 X;  3BVW A;  4EZW A;  4R5K A;  1I4T A;  4EZX A;  4H8S A;  3EJR A;  3ER9 B;  2V0O A;  3B52 X;  4EZT A;  3F7W A;  4AZ6 A;  4IWQ A;  2YPS A;  1O7D B;  3HPB A;  4EZU A;  1I49 A;  2F18 A;  3IQ2 A;  4EZQ A;  3ERC C;  1TQV A;  1U00 A;  4I1Q A;  3BUI A;  3BVX A;  2L73 A;  1QWU A;  4JWI A;  3CV5 A;  3I04 A;  1R34 A;  3T48 A;  4IKD A;  3D2F A;  2F7O A;  2YIA A;  2Z8Y A;  3P0C A;  3PLT A;  1PS3 A;  4AVM A;  2RAJ A;  3O3N B;  3OHX M;  2ETT A;  2PMR A;  2YI9 A;  4KIK B;  2WIN M;  3QNJ A;  2EFL A;  3RV1 A;  4AZG A;  2OZN B;  3EJU A;  4WPC A;  2CSK A;  5FIG A;  3BUD A;  4HYB A;  3T46 A;  3D4Z A;  3Q84 A;  1GNT A;  3D51 A;  4R5G A;  2KHO A;  4JWC A;  1DKZ A;  2YL5 A;  2X5C A;  4AZH A;  5C5B A;  4IWP A;  4IWO A;  1UPX A;  1W9M A;  3KDR A;  3T49 A;  4ATM A;  1DKY A;  1OCS A;  4HR1 A;  2CZO A;  3OWG A;  3BUB A;  3L3O M;  4R5L A;  2WYI A;  3C7N A;  4JNE A;  2F7R A;  3FD9 A;  4AZC A;  3EJS A;  3B51 X;  1SU7 A;  1E9V A;  2YIV X;  4JWD A;  3I01 A;  4IKB A;  3SYV A;  1O7D C;  2EFK A;  2Q13 A;  4PQP A;  2D1L A;  4JWE A;  2WWE A;  4B9Q A;  1KMD A;  1OAO A;  2OBL A;  4R5I A;  1WDZ A;  1E2U A;  2X3V A;  3O3O B;  4JNF A;  1LQ7 A;  2YLL A;  3O3M B;  4PZG A;  1O7K A;  3KAV A;  1XTE A;  2REA A;  4EZV A;  4FM3 A;  2Z0V A;  2RAK A;  2RED A;  2QKW A;  1GN9 A;  3QE6 A;  1I4L A;  1JQK A;  4UDY X;  2OW6 A;  3M3W A;  1HTY A;  1I4D A;  2ND1 A;  3DX2 A;  2F1A A;  1KQ6 A;  1HXK A;  5KBP A;  2MI7 A;  3BUP A;  4NQI A;  2YI8 A;  4D8J A;  3DDG A;  2OBM A;  2Z0N A;  1GD5 A;  2GF4 A;  3DX4 A;  2YL8 A;  1MJG A;  4UDX X;  3HAJ A;  1GNL A;  1R5E A;  2FIC A;  1X03 A;  2X3W A;  4AZ9 A;  2AR5 A;  4IM2 A;  1ZWW A;  1X04 A;  3EJP A;  2ELB A;  5C5B B;  4M0M A;  4JLC A;  3QWE A;  3DX1 A;  4HR1 B;  1XTN A;  2WYH A;  2IWL X;  4PO2 A;  2YL9 A;  4AZ7 A;  3D50 A;  1URU A;  1Y2O A;  3BVT A;  2V14 A;  3B53 X;  2RAI A;  2V6V A;  3LUI A;  4P2J A;  4IKB B;  2F7P A;  2FYV A;  2EWF A;  3HPC X;  2JNS A; 
#chains in the Genus database with same CATH homology
 2C08 A;  3P0C A;  3PLT A;  4AVM A;  3HAH A;  4PZG A;  1O7K A;  2RAJ A;  4HAS A;  1XTE A;  2ETT A;  2REA A;  4DYL A;  4FZS A;  2Z0V A;  3FOG A;  2RAK A;  2RED A;  2EFL A;  4WPE A;  4BNE A;  4WPC A;  2D4C A;  2CSK A;  3QE6 A;  1I4L A;  4NSW A;  2YKT A;  2I4K A;  3CAZ A;  3M3W A;  3OK8 A;  2X3X A;  1I4D A;  4P2I A;  3Q84 A;  1KQ6 A;  2DYB A;  3HAI A;  2Z0O A;  4PQO A;  4NQI A;  4BGJ A;  2Z0N A;  3ABH A;  1GD5 A;  3I2W A;  4OXW A;  5C5B A;  3HAJ A;  2FIC A;  3ACO A;  4ATM A;  1OCS A;  3SOG A;  1X03 A;  2CZO A;  3LLL A;  2X3W A;  4AZ9 A;  2AR5 A;  1ZWW A;  1X04 A;  1I4T A;  4ON3 A;  2Q12 A;  2ELB A;  4H8S A;  5C5B B;  3QWE A;  1H6H A;  3Q0K A;  4IKB A;  3SYV A;  1XTN A;  3G9G A;  2V0O A;  2IWL X;  2EFK A;  2Q13 A;  4AKV A;  2D1L A;  4PQP A;  1URU A;  2YPS A;  1Y2O A;  3HPB A;  1I49 A;  2V14 A;  3IQ2 A;  2RAI A;  3DYT A;  2WWE A;  2V6V A;  3LUI A;  4I1Q A;  4P2J A;  4IKB B;  2L73 A;  1KMD A;  1WDZ A;  4DCN C;  4IKD A;  2X3V A;  3HPC X;  1OCU A;  3QNI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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