2RAKA

Pi(3)p bound px-bar membrane remodeling unit of sorting nexin 9
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
382
structure length
382
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 128
structure length 382
sequence length 382
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2rakA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2rakA02
4I1QA 3DYTA 1I4LA 3P0CA 3QE6A 4P2IA 3QWEA 3OK8A 2DYBA 1I4DA 1GD5A 3SYVA 1OCSA 4AKVA 2WWEA 4BNEA 2CZOA 4FZSA 3CAZA 1OCUA 4AZ9A 1KMDA 4H8SA 4PZGA 1Y2OA 1URUA 2D4CA 2Q13A 3HAHA 1X03A 1I4TA 2RAKA 2V0OA 5C5BB 3ABHA 2ETTA 2Z0NA 2FICA 3HPCX 2IWLX 3Q84A 2X3VA 3QNIA 2X3WA 4HASA 4WPCA 4DYLA 1O7KA 4P2JA 1WDZA 2L73A 3HAIA 3M3WA 4AVMA 2AR5A 3LLLA 3FOGA 4NQIA 4IKDA 1H6HA 2EFLA 3I2WA 2RAIA 2REAA 4IKBA 1XTEA 3IQ2A 3PLTA 4PQOA 4ON3A 2X3XA 3SOGA 4WPEA 2I4KA 2YPSA 3Q0KA 2D1LA 2EFKA 2Z0OA 4ATMA 1ZWWA 4BGJA 3G9GA 4DCNC 1KQ6A 4NSWA 4PQPA 3HPBA 3HAJA 2ELBA 2YKTA 3LUIA 2V6VA 2REDA 2Z0VA 1X04A 2V14A 3ACOA 2Q12A 2C08A 5C5BA 4OXWA 2RAJA 4IKBB 1I49A 1XTNA 2CSKA
chains in the Genus database with same CATH superfamily
4I1QA 3DYTA 3O3MB 3KDRA 2N3KA 2GA9D 4P2IA 4HR1A 1O7DC 2OBLA 3VEAA 4IWPA 3DPOA 2YLLA 1I4DA 1UPXA 1SUFA 3OWGA 1U00A 2WWEA 4BNEA 3CZSA 2ND0A 4HR1B 3CAZA 5TKYA 3VKHA 4R5JA 4PZGA 1URUA 2F7PA 2Q13A 3HAHA 3KAVA 4JN4A 2RAKA 4JWDA 3ER9B 2F1BA 4UDYX 1OA0A 2X3VA 3DX2A 2F7QA 4FZOA 2YI8A 3B53X 4P2JA 4AZIA 4JWEA 2EWFA 2PY6A 3HAIA 3M3WA 3T48A 3I2WA 1GNLA 1QWUA 3LVTA 4PQOA 1W9MA 3B52X 4AZBA 4JNEA 3GI7A 4R5IA 4IM3A 2Z0OA 3CV5A 4BGJA 4EZUA 2MI7A 3RPMA 4EZNA 2YL6A 4R5LA 2FYVA 3HPBA 2YKTA 3DPPA 2Z0VA 4JLCA 4EZYA 5KBPA 2OO2A 2Q12A 2WYIA 4E81A 4OXWA 3QA8A 2CSKA 4HY9A 4JWCA 3RV0A 1I4LA 3BUDA 3BVXA 3QE6A 2DYBA 3SYVA 2JNSA 4AZ5A 2RT6A 2YIVX 4IW0A 4B9QA 4IM2A 3BVVA 3BVTA 4AZ7A 4FM3A 1Y2OA 2X5CA 2YIAA 1MJGA 3BUIA 3VEBA 4HYBA 2YIBA 4E3CA 4F01A 1I4TA 2F7RA 3D50A 3O3NB 5C5BB 4IWQA 1QWNA 4M0MA 1DKYA 3HPCX 3Q84A 4EZTA 4WPCA 1O7KA 2F1AA 2L73A 2AR5A 3LLLA 1H6HA 2EFLA 2QXLA 4IKBA 2WYHA 1DKZA 2ALWA 3D4ZA 3PLTA 4ON3A 2QKWA 5FLEX 1TQVA 3FD9A 3T4AG 3Q0KA 1E9VA 4EZOA 3ER8C 3DX1A 1ZWWA 4EZPA 2GF4A 3G9GA 2PMRA 3I01A 1LQ7A 1SU8A 3HAJA 3DDFA 3LUIA 5E84A 1OAOA 2V6VA 3D2EA 3RV1A 1X04A 3ACOA 2C08A 4EZZA 2YL8A 3I39X 3CKDA 3BLBA 3P0CA 2ZXQA 3QWEA 3BVWA 3OK8A 1QX1A 4NPHA 1TQSA 4AKVA 2Z8YA 4F00A 4AZCA 2OW7A 4D8JA 3EJSA 1YWMA 3O3OB 2LM0A 1OCUA 4AZ9A 3D4YA 3L3PA 4EZVA 2QFFA 4AZGA 3DX4A 4UDXX 4AZCB 3UITA 2GAFD 4R5GA 4JL9A 2JNKA 4G6QA 3EJTA 4JNFA 2Z0NA 4EZQA 2FICA 2YI9A 3A98A 1HWWA 3EJRA 3QNIA 4EZSA 4DYLA 5FIGA 3D2FA 4KIKA 4AZHA 4AVMA 1HTYA 1OA1A 3FOGA 4NQIA 4IKDA 2REAA 3T46A 3ERCC 2OBMA 2ND1A 3SOGA 3QNJA 4AZ6A 3B51X 1DKXA 2YL9A 3EJPA 1E1DA 3EJQA 1TQWA 4DCNC 4H6IA 1HXKA 3EJUA 2EX3B 1E2UA 3DX3A 2F18A 2LXYA 3DPQA 3CZNA 2RAJA 4IKBB 1XTNA 1TQUA 4IWOA 4EZRA 3T49A 3T47A 2OZNB 1GD5A 1OCSA 1R34A 1SU6A 4EZWA 2OW6A 2CZOA 4FZSA 1KMDA 4H8SA 4JWIA 2D4CA 3CVRA 4R5KA 3KAWA 1X03A 2V0OA 3ABHA 2ETTA 3ZEDA 3OHXM 2IWLX 2X3WA 4HASA 2O0I1 3I04A 2WINM 1ZYLA 2NCZA 1WDZA 3BUBA 1R5EA 2YL5A 2YLAA 3F7WA 2RAIA 1XTEA 3IQ2A 1R33A 3L3OM 4H6HA 3DX0A 1TQTA 3D52A 1JQKA 2X3XA 3BVUA 4WPEA 4EZXA 2I4KA 2YPSA 1GN9A 3D51A 4IM0A 2D1LA 2EFKA 3C7NA 4ATMA 1PS3A 3BUQA 1KQ6A 4NSWA 4FZPA 4PQPA 4KIKB 4PO2A 3DDGA 2ELBA 2F7OA 2REDA 3BUPA 2V14A 1SU7A 1GNTA 3LMFA 5C5BA 1O7DB 1I49A 2KHOA
chains in the Genus database with same CATH topology
4I1QA 3DYTA 1I4LA 3P0CA 3QE6A 4P2IA 3QWEA 3OK8A 2DYBA 1I4DA 1GD5A 3SYVA 1OCSA 4AKVA 2WWEA 4BNEA 2CZOA 4FZSA 3CAZA 1OCUA 4AZ9A 1KMDA 4H8SA 4PZGA 1Y2OA 1URUA 2D4CA 2Q13A 3HAHA 1X03A 1I4TA 2RAKA 2V0OA 5C5BB 3ABHA 2ETTA 2Z0NA 2FICA 3HPCX 2IWLX 3Q84A 2X3VA 3QNIA 2X3WA 4HASA 4WPCA 4DYLA 1O7KA 4P2JA 1WDZA 2L73A 3HAIA 3M3WA 4AVMA 2AR5A 3LLLA 3FOGA 4NQIA 4IKDA 1H6HA 2EFLA 3I2WA 2RAIA 2REAA 4IKBA 1XTEA 3IQ2A 3PLTA 4PQOA 4ON3A 2X3XA 3SOGA 4WPEA 2I4KA 2YPSA 3Q0KA 2D1LA 2EFKA 2Z0OA 4ATMA 1ZWWA 4BGJA 3G9GA 4DCNC 1KQ6A 4NSWA 4PQPA 3HPBA 3HAJA 2ELBA 2YKTA 3LUIA 2V6VA 2REDA 2Z0VA 1X04A 2V14A 3ACOA 2Q12A 2C08A 5C5BA 4OXWA 2RAJA 4IKBB 1I49A 1XTNA 2CSKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I1Q A;  3DYT A;  1I4L A;  3P0C A;  3QE6 A;  4P2I A;  3QWE A;  3OK8 A;  2DYB A;  1I4D A;  1GD5 A;  3SYV A;  1OCS A;  4AKV A;  2WWE A;  4BNE A;  2CZO A;  4FZS A;  3CAZ A;  1OCU A;  4AZ9 A;  1KMD A;  4H8S A;  4PZG A;  1Y2O A;  1URU A;  2D4C A;  2Q13 A;  3HAH A;  1X03 A;  1I4T A;  2RAK A;  2V0O A;  5C5B B;  3ABH A;  2ETT A;  2Z0N A;  2FIC A;  3HPC X;  2IWL X;  3Q84 A;  2X3V A;  3QNI A;  2X3W A;  4HAS A;  4WPC A;  4DYL A;  1O7K A;  4P2J A;  1WDZ A;  2L73 A;  3HAI A;  3M3W A;  4AVM A;  2AR5 A;  3LLL A;  3FOG A;  4NQI A;  4IKD A;  1H6H A;  2EFL A;  3I2W A;  2RAI A;  2REA A;  4IKB A;  1XTE A;  3IQ2 A;  3PLT A;  4PQO A;  4ON3 A;  2X3X A;  3SOG A;  4WPE A;  2I4K A;  2YPS A;  3Q0K A;  2D1L A;  2EFK A;  2Z0O A;  4ATM A;  1ZWW A;  4BGJ A;  3G9G A;  4DCN C;  1KQ6 A;  4NSW A;  4PQP A;  3HPB A;  3HAJ A;  2ELB A;  2YKT A;  3LUI A;  2V6V A;  2RED A;  2Z0V A;  1X04 A;  2V14 A;  3ACO A;  2Q12 A;  2C08 A;  5C5B A;  4OXW A;  2RAJ A;  4IKB B;  1I49 A;  1XTN A;  2CSK A; 
#chains in the Genus database with same CATH topology
 4I1Q A;  3DYT A;  3O3M B;  3KDR A;  2N3K A;  2GA9 D;  4P2I A;  4HR1 A;  1O7D C;  2OBL A;  3VEA A;  4IWP A;  3DPO A;  2YLL A;  1I4D A;  1UPX A;  1SUF A;  3OWG A;  1U00 A;  2WWE A;  4BNE A;  3CZS A;  2ND0 A;  4HR1 B;  3CAZ A;  5TKY A;  3VKH A;  4R5J A;  4PZG A;  1URU A;  2F7P A;  2Q13 A;  3HAH A;  3KAV A;  4JN4 A;  2RAK A;  4JWD A;  3ER9 B;  2F1B A;  4UDY X;  1OA0 A;  2X3V A;  3DX2 A;  2F7Q A;  4FZO A;  2YI8 A;  3B53 X;  4P2J A;  4AZI A;  4JWE A;  2EWF A;  2PY6 A;  3HAI A;  3M3W A;  3T48 A;  3I2W A;  1GNL A;  1QWU A;  3LVT A;  4PQO A;  1W9M A;  3B52 X;  4AZB A;  4JNE A;  3GI7 A;  4R5I A;  4IM3 A;  2Z0O A;  3CV5 A;  4BGJ A;  4EZU A;  2MI7 A;  3RPM A;  4EZN A;  2YL6 A;  4R5L A;  2FYV A;  3HPB A;  2YKT A;  3DPP A;  2Z0V A;  4JLC A;  4EZY A;  5KBP A;  2OO2 A;  2Q12 A;  2WYI A;  4E81 A;  4OXW A;  3QA8 A;  2CSK A;  4HY9 A;  4JWC A;  3RV0 A;  1I4L A;  3BUD A;  3BVX A;  3QE6 A;  2DYB A;  3SYV A;  2JNS A;  4AZ5 A;  2RT6 A;  2YIV X;  4IW0 A;  4B9Q A;  4IM2 A;  3BVV A;  3BVT A;  4AZ7 A;  4FM3 A;  1Y2O A;  2X5C A;  2YIA A;  1MJG A;  3BUI A;  3VEB A;  4HYB A;  2YIB A;  4E3C A;  4F01 A;  1I4T A;  2F7R A;  3D50 A;  3O3N B;  5C5B B;  4IWQ A;  1QWN A;  4M0M A;  1DKY A;  3HPC X;  3Q84 A;  4EZT A;  4WPC A;  1O7K A;  2F1A A;  2L73 A;  2AR5 A;  3LLL A;  1H6H A;  2EFL A;  2QXL A;  4IKB A;  2WYH A;  1DKZ A;  2ALW A;  3D4Z A;  3PLT A;  4ON3 A;  2QKW A;  5FLE X;  1TQV A;  3FD9 A;  3T4A G;  3Q0K A;  1E9V A;  4EZO A;  3ER8 C;  3DX1 A;  1ZWW A;  4EZP A;  2GF4 A;  3G9G A;  2PMR A;  3I01 A;  1LQ7 A;  1SU8 A;  3HAJ A;  3DDF A;  3LUI A;  5E84 A;  1OAO A;  2V6V A;  3D2E A;  3RV1 A;  1X04 A;  3ACO A;  2C08 A;  4EZZ A;  2YL8 A;  3I39 X;  3CKD A;  3BLB A;  3P0C A;  2ZXQ A;  3QWE A;  3BVW A;  3OK8 A;  1QX1 A;  4NPH A;  1TQS A;  4AKV A;  2Z8Y A;  4F00 A;  4AZC A;  2OW7 A;  4D8J A;  3EJS A;  1YWM A;  3O3O B;  2LM0 A;  1OCU A;  4AZ9 A;  3D4Y A;  3L3P A;  4EZV A;  2QFF A;  4AZG A;  3DX4 A;  4UDX X;  4AZC B;  3UIT A;  2GAF D;  4R5G A;  4JL9 A;  2JNK A;  4G6Q A;  3EJT A;  4JNF A;  2Z0N A;  4EZQ A;  2FIC A;  2YI9 A;  3A98 A;  1HWW A;  3EJR A;  3QNI A;  4EZS A;  4DYL A;  5FIG A;  3D2F A;  4KIK A;  4AZH A;  4AVM A;  1HTY A;  1OA1 A;  3FOG A;  4NQI A;  4IKD A;  2REA A;  3T46 A;  3ERC C;  2OBM A;  2ND1 A;  3SOG A;  3QNJ A;  4AZ6 A;  3B51 X;  1DKX A;  2YL9 A;  3EJP A;  1E1D A;  3EJQ A;  1TQW A;  4DCN C;  4H6I A;  1HXK A;  3EJU A;  2EX3 B;  1E2U A;  3DX3 A;  2F18 A;  2LXY A;  3DPQ A;  3CZN A;  2RAJ A;  4IKB B;  1XTN A;  1TQU A;  4IWO A;  4EZR A;  3T49 A;  3T47 A;  2OZN B;  1GD5 A;  1OCS A;  1R34 A;  1SU6 A;  4EZW A;  2OW6 A;  2CZO A;  4FZS A;  1KMD A;  4H8S A;  4JWI A;  2D4C A;  3CVR A;  4R5K A;  3KAW A;  1X03 A;  2V0O A;  3ABH A;  2ETT A;  3ZED A;  3OHX M;  2IWL X;  2X3W A;  4HAS A;  2O0I 1;  3I04 A;  2WIN M;  1ZYL A;  2NCZ A;  1WDZ A;  3BUB A;  1R5E A;  2YL5 A;  2YLA A;  3F7W A;  2RAI A;  1XTE A;  3IQ2 A;  1R33 A;  3L3O M;  4H6H A;  3DX0 A;  1TQT A;  3D52 A;  1JQK A;  2X3X A;  3BVU A;  4WPE A;  4EZX A;  2I4K A;  2YPS A;  1GN9 A;  3D51 A;  4IM0 A;  2D1L A;  2EFK A;  3C7N A;  4ATM A;  1PS3 A;  3BUQ A;  1KQ6 A;  4NSW A;  4FZP A;  4PQP A;  4KIK B;  4PO2 A;  3DDG A;  2ELB A;  2F7O A;  2RED A;  3BUP A;  2V14 A;  1SU7 A;  1GNT A;  3LMF A;  5C5B A;  1O7D B;  1I49 A;  2KHO A; 
#chains in the Genus database with same CATH homology
 4I1Q A;  3DYT A;  1I4L A;  3P0C A;  3QE6 A;  4P2I A;  3QWE A;  3OK8 A;  2DYB A;  1I4D A;  1GD5 A;  3SYV A;  1OCS A;  4AKV A;  2WWE A;  4BNE A;  2CZO A;  4FZS A;  3CAZ A;  1OCU A;  4AZ9 A;  1KMD A;  4H8S A;  4PZG A;  1Y2O A;  1URU A;  2D4C A;  2Q13 A;  3HAH A;  1X03 A;  1I4T A;  2RAK A;  2V0O A;  5C5B B;  3ABH A;  2ETT A;  2Z0N A;  2FIC A;  3HPC X;  2IWL X;  3Q84 A;  2X3V A;  3QNI A;  2X3W A;  4HAS A;  4WPC A;  4DYL A;  1O7K A;  4P2J A;  1WDZ A;  2L73 A;  3HAI A;  3M3W A;  4AVM A;  2AR5 A;  3LLL A;  3FOG A;  4NQI A;  4IKD A;  1H6H A;  2EFL A;  3I2W A;  2RAI A;  2REA A;  4IKB A;  1XTE A;  3IQ2 A;  3PLT A;  4PQO A;  4ON3 A;  2X3X A;  3SOG A;  4WPE A;  2I4K A;  2YPS A;  3Q0K A;  2D1L A;  2EFK A;  2Z0O A;  4ATM A;  1ZWW A;  4BGJ A;  3G9G A;  4DCN C;  1KQ6 A;  4NSW A;  4PQP A;  3HPB A;  3HAJ A;  2ELB A;  2YKT A;  3LUI A;  2V6V A;  2RED A;  2Z0V A;  1X04 A;  2V14 A;  3ACO A;  2Q12 A;  2C08 A;  5C5B A;  4OXW A;  2RAJ A;  4IKB B;  1I49 A;  1XTN A;  2CSK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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