2RAKA

Pi(3)p bound px-bar membrane remodeling unit of sorting nexin 9
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
382
structure length
382
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 128
structure length 382
sequence length 382
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2rakA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2rakA02
2EFKA 2YKTA 3P0CA 1I49A 4I1QA 5C5BA 1O7KA 2Q13A 2V6VA 1H6HA 2ETTA 2V0OA 2Z0VA 3ACOA 3LUIA 4PZGA 2RAKA 2X3WA 2YPSA 4AVMA 3QNIA 4WPCA 4BGJA 2RAJA 3QWEA 2EFLA 4FZSA 2Q12A 2L73A 2REAA 3HAHA 1I4LA 1URUA 4P2JA 2DYBA 4DYLA 3HPBA 4ON3A 2V14A 1OCSA 4IKBB 2D4CA 1I4DA 2I4KA 1I4TA 4IKDA 3ABHA 2FICA 3QE6A 3SYVA 3PLTA 1X03A 3G9GA 1WDZA 4NQIA 2Z0OA 4AKVA 2C08A 3HPCX 3SOGA 2ELBA 4PQPA 4P2IA 4DCNC 3LLLA 4ATMA 2AR5A 3M3WA 4IKBA 3I2WA 1XTEA 3IQ2A 3CAZA 2REDA 4AZ9A 2X3XA 1Y2OA 2X3VA 3FOGA 2RAIA 2Z0NA 4BNEA 1KQ6A 1XTNA 5C5BB 4OXWA 1GD5A 2D1LA 4H8SA 4NSWA 3HAJA 3HAIA 2WWEA 2CZOA 4WPEA 1X04A 3OK8A 1KMDA 4HASA 1ZWWA 2IWLX 2CSKA 4PQOA 3Q84A 1OCUA 3DYTA 3Q0KA
chains in the Genus database with same CATH superfamily
2EFKA 3D2FA 1TQWA 2JNSA 2Q13A 4E3CA 2WYIA 2YPSA 4KIKA 1TQTA 2WINM 1W9MA 1YWMA 4BGJA 4UDYX 4EZNA 2O0I1 3B52X 3BUPA 1OA1A 3BVUA 2N3KA 1GNTA 1SUFA 2YIAA 4IM3A 4EZUA 2RT6A 3CKDA 1GN9A 4AZIA 3BVTA 3ER9B 1SU8A 3CZSA 1DKZA 1WDZA 2PY6A 4H6IA 2F7PA 4PQPA 2F1AA 4DCNC 4EZQA 3DX3A 4IWQA 3DDGA 2EWFA 2X3XA 4R5LA 3FOGA 3DX4A 2Z0NA 4BNEA 1R34A 2ND0A 4AZGA 1O7DB 1XTNA 2ZXQA 2QFFA 4IW0A 1QWNA 4NPHA 3LMFA 2D1LA 4R5GA 3BUQA 1E2UA 3HAJA 2YI9A 3HAIA 2F7QA 1UPXA 1ZWWA 5FIGA 5FLEX 3F7WA 3VEBA 4AZCB 3GI7A 3QA8A 2F1BA 2C08A 3ZEDA 4H6HA 3P0CA 5C5BA 3T48A 3A98A 4FZPA 3BUDA 4G6QA 2V6VA 1HXKA 2V0OA 2Z0VA 4HYBA 3DX1A 3BVWA 1MJGA 1HWWA 4JNEA 3QNIA 1OA0A 4WPCA 1JQKA 2RAJA 4AZHA 3QWEA 3C7NA 2ND1A 1E1DA 2X5CA 4EZTA 1DKXA 3HAHA 1O7DC 3EJSA 4ON3A 2V14A 3ERCC 1OCSA 3RV0A 2F7RA 4HY9A 4JN4A 2GF4A 3ABHA 3T47A 4AKVA 1TQSA 4R5IA 3HPCX 3SOGA 3T49A 1E9VA 1R5EA 1SU7A 4P2IA 3B53X 3LLLA 4ATMA 2AR5A 3M3WA 4IKBA 3DX2A 3CAZA 3LVTA 3DPQA 2RAIA 1LQ7A 2KHOA 2ALWA 2WWEA 4WPEA 2OW6A 4KIKB 4HR1A 4EZSA 4PQOA 1HTYA 3D4ZA 2YLLA 4JLCA 3UITA 3EJRA 4I1QA 4JWIA 1O7KA 3T4AG 4R5JA 2YI8A 2F18A 5E84A 3LUIA 4JWCA 4PZGA 3DPOA 4D8JA 2RAKA 2X3WA 4AVMA 3T46A 4M0MA 2EFLA 1R33A 2REAA 4JNFA 4EZWA 1SU6A 4JWEA 3RPMA 3D2EA 2DYBA 3HPBA 4P2JA 3VEAA 3BUIA 3KDRA 2OBMA 3KAWA 4IM0A 2I4KA 2JNKA 2FICA 3O3OB 3QE6A 3PLTA 4NQIA 2Z0OA 3VKHA 1ZYLA 4EZXA 3D4YA 2WYHA 1OAOA 3ER8C 2GA9D 1GNLA 4PO2A 3O3MB 1XTEA 3IQ2A 2Z8YA 3BVVA 4UDXX 2YL6A 3DPPA 3I01A 1KQ6A 5C5BB 4OXWA 2OZNB 1GD5A 3QNJA 3I39X 1TQVA 3BLBA 2CZOA 1X04A 3OK8A 3BVXA 4HASA 3KAVA 2IWLX 2CSKA 4E81A 2YIBA 1QX1A 2LXYA 3D50A 3Q84A 1OCUA 3DDFA 4EZZA 2OW7A 3D52A 3BUBA 3FD9A 2YKTA 2YLAA 1I49A 4AZ5A 3D51A 4B9QA 3EJPA 1H6HA 2ETTA 2OBLA 3L3OM 3ACOA 4EZPA 1TQUA 3I04A 4JWDA 4IWOA 4FZOA 4AZCA 1PS3A 3CV5A 4FZSA 2Q12A 2L73A 4AZ7A 3EJUA 4F01A 4IWPA 4R5KA 1I4LA 1URUA 4DYLA 2FYVA 4JL9A 3OHXM 2LM0A 2F7OA 4IKBB 2D4CA 1I4DA 3CVRA 5TKYA 3EJQA 2YIVX 1I4TA 4IKDA 3SYVA 4EZRA 1X03A 2GAFD 3G9GA 3DX0A 2NCZA 4EZOA 3EJTA 4EZVA 2ELBA 3CZNA 2OO2A 1DKYA 2YL5A 4AZ6A 3RV1A 4HR1B 3O3NB 3I2WA 2REDA 4AZ9A 1Y2OA 2YL8A 2X3VA 3B51X 4IM2A 4F00A 1QWUA 2MI7A 2EX3B 3OWGA 2PMRA 1U00A 4AZBA 4H8SA 4NSWA 4EZYA 1KMDA 3L3PA 3DYTA 2YL9A 2QXLA 4FM3A 5KBPA 3Q0KA 2QKWA
chains in the Genus database with same CATH topology
2EFKA 2YKTA 3P0CA 1I49A 4I1QA 5C5BA 1O7KA 2Q13A 2V6VA 1H6HA 2ETTA 2V0OA 2Z0VA 3ACOA 3LUIA 4PZGA 2RAKA 2X3WA 2YPSA 4AVMA 3QNIA 4WPCA 4BGJA 2RAJA 3QWEA 2EFLA 4FZSA 2Q12A 2L73A 2REAA 3HAHA 1I4LA 1URUA 4P2JA 2DYBA 4DYLA 3HPBA 4ON3A 2V14A 1OCSA 4IKBB 2D4CA 1I4DA 2I4KA 1I4TA 4IKDA 3ABHA 2FICA 3QE6A 3SYVA 3PLTA 1X03A 3G9GA 1WDZA 4NQIA 2Z0OA 4AKVA 2C08A 3HPCX 3SOGA 2ELBA 4PQPA 4P2IA 4DCNC 3LLLA 4ATMA 2AR5A 3M3WA 4IKBA 3I2WA 1XTEA 3IQ2A 3CAZA 2REDA 4AZ9A 2X3XA 1Y2OA 2X3VA 3FOGA 2RAIA 2Z0NA 4BNEA 1KQ6A 1XTNA 5C5BB 4OXWA 1GD5A 2D1LA 4H8SA 4NSWA 3HAJA 3HAIA 2WWEA 2CZOA 4WPEA 1X04A 3OK8A 1KMDA 4HASA 1ZWWA 2IWLX 2CSKA 4PQOA 3Q84A 1OCUA 3DYTA 3Q0KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EFK A;  2YKT A;  3P0C A;  1I49 A;  4I1Q A;  5C5B A;  1O7K A;  2Q13 A;  2V6V A;  1H6H A;  2ETT A;  2V0O A;  2Z0V A;  3ACO A;  3LUI A;  4PZG A;  2RAK A;  2X3W A;  2YPS A;  4AVM A;  3QNI A;  4WPC A;  4BGJ A;  2RAJ A;  3QWE A;  2EFL A;  4FZS A;  2Q12 A;  2L73 A;  2REA A;  3HAH A;  1I4L A;  1URU A;  4P2J A;  2DYB A;  4DYL A;  3HPB A;  4ON3 A;  2V14 A;  1OCS A;  4IKB B;  2D4C A;  1I4D A;  2I4K A;  1I4T A;  4IKD A;  3ABH A;  2FIC A;  3QE6 A;  3SYV A;  3PLT A;  1X03 A;  3G9G A;  1WDZ A;  4NQI A;  2Z0O A;  4AKV A;  2C08 A;  3HPC X;  3SOG A;  2ELB A;  4PQP A;  4P2I A;  4DCN C;  3LLL A;  4ATM A;  2AR5 A;  3M3W A;  4IKB A;  3I2W A;  1XTE A;  3IQ2 A;  3CAZ A;  2RED A;  4AZ9 A;  2X3X A;  1Y2O A;  2X3V A;  3FOG A;  2RAI A;  2Z0N A;  4BNE A;  1KQ6 A;  1XTN A;  5C5B B;  4OXW A;  1GD5 A;  2D1L A;  4H8S A;  4NSW A;  3HAJ A;  3HAI A;  2WWE A;  2CZO A;  4WPE A;  1X04 A;  3OK8 A;  1KMD A;  4HAS A;  1ZWW A;  2IWL X;  2CSK A;  4PQO A;  3Q84 A;  1OCU A;  3DYT A;  3Q0K A; 
#chains in the Genus database with same CATH topology
 2EFK A;  3D2F A;  1TQW A;  2JNS A;  2Q13 A;  4E3C A;  2WYI A;  2YPS A;  4KIK A;  1TQT A;  2WIN M;  1W9M A;  1YWM A;  4BGJ A;  4UDY X;  4EZN A;  2O0I 1;  3B52 X;  3BUP A;  1OA1 A;  3BVU A;  2N3K A;  1GNT A;  1SUF A;  2YIA A;  4IM3 A;  4EZU A;  2RT6 A;  3CKD A;  1GN9 A;  4AZI A;  3BVT A;  3ER9 B;  1SU8 A;  3CZS A;  1DKZ A;  1WDZ A;  2PY6 A;  4H6I A;  2F7P A;  4PQP A;  2F1A A;  4DCN C;  4EZQ A;  3DX3 A;  4IWQ A;  3DDG A;  2EWF A;  2X3X A;  4R5L A;  3FOG A;  3DX4 A;  2Z0N A;  4BNE A;  1R34 A;  2ND0 A;  4AZG A;  1O7D B;  1XTN A;  2ZXQ A;  2QFF A;  4IW0 A;  1QWN A;  4NPH A;  3LMF A;  2D1L A;  4R5G A;  3BUQ A;  1E2U A;  3HAJ A;  2YI9 A;  3HAI A;  2F7Q A;  1UPX A;  1ZWW A;  5FIG A;  5FLE X;  3F7W A;  3VEB A;  4AZC B;  3GI7 A;  3QA8 A;  2F1B A;  2C08 A;  3ZED A;  4H6H A;  3P0C A;  5C5B A;  3T48 A;  3A98 A;  4FZP A;  3BUD A;  4G6Q A;  2V6V A;  1HXK A;  2V0O A;  2Z0V A;  4HYB A;  3DX1 A;  3BVW A;  1MJG A;  1HWW A;  4JNE A;  3QNI A;  1OA0 A;  4WPC A;  1JQK A;  2RAJ A;  4AZH A;  3QWE A;  3C7N A;  2ND1 A;  1E1D A;  2X5C A;  4EZT A;  1DKX A;  3HAH A;  1O7D C;  3EJS A;  4ON3 A;  2V14 A;  3ERC C;  1OCS A;  3RV0 A;  2F7R A;  4HY9 A;  4JN4 A;  2GF4 A;  3ABH A;  3T47 A;  4AKV A;  1TQS A;  4R5I A;  3HPC X;  3SOG A;  3T49 A;  1E9V A;  1R5E A;  1SU7 A;  4P2I A;  3B53 X;  3LLL A;  4ATM A;  2AR5 A;  3M3W A;  4IKB A;  3DX2 A;  3CAZ A;  3LVT A;  3DPQ A;  2RAI A;  1LQ7 A;  2KHO A;  2ALW A;  2WWE A;  4WPE A;  2OW6 A;  4KIK B;  4HR1 A;  4EZS A;  4PQO A;  1HTY A;  3D4Z A;  2YLL A;  4JLC A;  3UIT A;  3EJR A;  4I1Q A;  4JWI A;  1O7K A;  3T4A G;  4R5J A;  2YI8 A;  2F18 A;  5E84 A;  3LUI A;  4JWC A;  4PZG A;  3DPO A;  4D8J A;  2RAK A;  2X3W A;  4AVM A;  3T46 A;  4M0M A;  2EFL A;  1R33 A;  2REA A;  4JNF A;  4EZW A;  1SU6 A;  4JWE A;  3RPM A;  3D2E A;  2DYB A;  3HPB A;  4P2J A;  3VEA A;  3BUI A;  3KDR A;  2OBM A;  3KAW A;  4IM0 A;  2I4K A;  2JNK A;  2FIC A;  3O3O B;  3QE6 A;  3PLT A;  4NQI A;  2Z0O A;  3VKH A;  1ZYL A;  4EZX A;  3D4Y A;  2WYH A;  1OAO A;  3ER8 C;  2GA9 D;  1GNL A;  4PO2 A;  3O3M B;  1XTE A;  3IQ2 A;  2Z8Y A;  3BVV A;  4UDX X;  2YL6 A;  3DPP A;  3I01 A;  1KQ6 A;  5C5B B;  4OXW A;  2OZN B;  1GD5 A;  3QNJ A;  3I39 X;  1TQV A;  3BLB A;  2CZO A;  1X04 A;  3OK8 A;  3BVX A;  4HAS A;  3KAV A;  2IWL X;  2CSK A;  4E81 A;  2YIB A;  1QX1 A;  2LXY A;  3D50 A;  3Q84 A;  1OCU A;  3DDF A;  4EZZ A;  2OW7 A;  3D52 A;  3BUB A;  3FD9 A;  2YKT A;  2YLA A;  1I49 A;  4AZ5 A;  3D51 A;  4B9Q A;  3EJP A;  1H6H A;  2ETT A;  2OBL A;  3L3O M;  3ACO A;  4EZP A;  1TQU A;  3I04 A;  4JWD A;  4IWO A;  4FZO A;  4AZC A;  1PS3 A;  3CV5 A;  4FZS A;  2Q12 A;  2L73 A;  4AZ7 A;  3EJU A;  4F01 A;  4IWP A;  4R5K A;  1I4L A;  1URU A;  4DYL A;  2FYV A;  4JL9 A;  3OHX M;  2LM0 A;  2F7O A;  4IKB B;  2D4C A;  1I4D A;  3CVR A;  5TKY A;  3EJQ A;  2YIV X;  1I4T A;  4IKD A;  3SYV A;  4EZR A;  1X03 A;  2GAF D;  3G9G A;  3DX0 A;  2NCZ A;  4EZO A;  3EJT A;  4EZV A;  2ELB A;  3CZN A;  2OO2 A;  1DKY A;  2YL5 A;  4AZ6 A;  3RV1 A;  4HR1 B;  3O3N B;  3I2W A;  2RED A;  4AZ9 A;  1Y2O A;  2YL8 A;  2X3V A;  3B51 X;  4IM2 A;  4F00 A;  1QWU A;  2MI7 A;  2EX3 B;  3OWG A;  2PMR A;  1U00 A;  4AZB A;  4H8S A;  4NSW A;  4EZY A;  1KMD A;  3L3P A;  3DYT A;  2YL9 A;  2QXL A;  4FM3 A;  5KBP A;  3Q0K A;  2QKW A; 
#chains in the Genus database with same CATH homology
 2EFK A;  2YKT A;  3P0C A;  1I49 A;  4I1Q A;  5C5B A;  1O7K A;  2Q13 A;  2V6V A;  1H6H A;  2ETT A;  2V0O A;  2Z0V A;  3ACO A;  3LUI A;  4PZG A;  2RAK A;  2X3W A;  2YPS A;  4AVM A;  3QNI A;  4WPC A;  4BGJ A;  2RAJ A;  3QWE A;  2EFL A;  4FZS A;  2Q12 A;  2L73 A;  2REA A;  3HAH A;  1I4L A;  1URU A;  4P2J A;  2DYB A;  4DYL A;  3HPB A;  4ON3 A;  2V14 A;  1OCS A;  4IKB B;  2D4C A;  1I4D A;  2I4K A;  1I4T A;  4IKD A;  3ABH A;  2FIC A;  3QE6 A;  3SYV A;  3PLT A;  1X03 A;  3G9G A;  1WDZ A;  4NQI A;  2Z0O A;  4AKV A;  2C08 A;  3HPC X;  3SOG A;  2ELB A;  4PQP A;  4P2I A;  4DCN C;  3LLL A;  4ATM A;  2AR5 A;  3M3W A;  4IKB A;  3I2W A;  1XTE A;  3IQ2 A;  3CAZ A;  2RED A;  4AZ9 A;  2X3X A;  1Y2O A;  2X3V A;  3FOG A;  2RAI A;  2Z0N A;  4BNE A;  1KQ6 A;  1XTN A;  5C5B B;  4OXW A;  1GD5 A;  2D1L A;  4H8S A;  4NSW A;  3HAJ A;  3HAI A;  2WWE A;  2CZO A;  4WPE A;  1X04 A;  3OK8 A;  1KMD A;  4HAS A;  1ZWW A;  2IWL X;  2CSK A;  4PQO A;  3Q84 A;  1OCU A;  3DYT A;  3Q0K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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