2RAIA

The px-bar membrane remodeling unit of sorting nexin 9
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
382
structure length
363
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 118
structure length 363
sequence length 382
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2raiA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2raiA02
3DYTA 2Q12A 2I4KA 3LUIA 2RAIA 1XTEA 1XTNA 1ZWWA 3P0CA 3CAZA 4I1QA 1WDZA 2V6VA 1Y2OA 2ETTA 2DYBA 2YPSA 2ELBA 2C08A 1OCSA 1KMDA 3LLLA 1KQ6A 2FICA 4WPEA 4OXWA 3QNIA 4PQOA 2D4CA 3G9GA 3HAHA 3QE6A 3SYVA 4HASA 2REAA 2Z0VA 2Z0OA 4BNEA 2V0OA 4FZSA 3QWEA 4ON3A 3FOGA 2X3XA 2EFLA 2X3VA 4DYLA 3ABHA 3OK8A 4P2JA 3PLTA 1I4LA 1O7KA 3IQ2A 4AVMA 4PQPA 3HPCX 4AKVA 3SOGA 4WPCA 1X04A 4IKBB 2CSKA 2Q13A 2L73A 4PZGA 2V14A 2IWLX 2Z0NA 1URUA 2REDA 4IKBA 2D1LA 4ATMA 2AR5A 2CZOA 3M3WA 1OCUA 4DCNC 2RAKA 1H6HA 4IKDA 4AZ9A 3HAIA 4H8SA 2RAJA 3Q84A 4P2IA 2EFKA 3HAJA 3ACOA 2X3WA 3I2WA 4NSWA 1GD5A 1X03A 1I4DA 5C5BB 4NQIA 4BGJA 3HPBA 2WWEA 3Q0KA 1I49A 2YKTA 1I4TA 5C5BA
chains in the Genus database with same CATH superfamily
3CZNA 3O3NB 1XTEA 1XTNA 2QXLA 1TQWA 3T46A 3D4ZA 4IWQA 1ZWWA 4B9QA 1HTYA 3LVTA 2YLAA 2EWFA 3CAZA 4R5LA 4JWEA 3EJTA 2ELBA 2C08A 4UDXX 1OA1A 4R5GA 3LLLA 3ER9B 4AZIA 4PQOA 3G9GA 2F18A 4HASA 3EJRA 2X5CA 2Z0VA 4R5IA 1E9VA 2Z0OA 1OA0A 2V0OA 3EJUA 1QWUA 3QWEA 3T47A 4AZBA 3BVXA 2PMRA 2MI7A 1DKZA 4FM3A 3ABHA 2JNKA 1I4LA 3I39X 4AZ7A 1W9MA 3VEAA 2YI9A 2WYHA 2QFFA 4PQPA 3L3OM 2Q13A 2EX3B 2IWLX 2REDA 3RV0A 5TKYA 4IW0A 4EZQA 4EZXA 4HY9A 1SU7A 4JL9A 2F7PA 3T4AG 1QWNA 3L3PA 4KIKB 2OBMA 2OBLA 1OAOA 4H8SA 2RAJA 4EZNA 3RPMA 2EFKA 3BUQA 3I2WA 4NSWA 1GD5A 2F7OA 4NPHA 2ZXQA 3DPQA 3BUDA 4G6QA 1HWWA 1YWMA 4EZTA 1I4TA 1DKYA 2YL5A 2FYVA 2I4KA 4EZOA 4EZYA 1TQUA 1UPXA 3DX1A 4AZCA 2OW6A 3P0CA 3BVVA 3KAWA 4I1QA 3BVTA 2V6VA 1Y2OA 2DYBA 2YPSA 3DX0A 4AZGA 4HR1B 4OXWA 3B51X 1O7DC 1LQ7A 3F7WA 3QE6A 5KBPA 2REAA 4AZ5A 4JWIA 4FZSA 1TQVA 4F01A 3FOGA 3UITA 2WINM 4JWDA 4DYLA 3BUPA 3B52X 3PLTA 1O7KA 1E2UA 4EZSA 3EJSA 3FD9A 4H6HA 3SOGA 4IKBB 1R33A 4IM2A 3GI7A 2L73A 2YL9A 4PZGA 2YLLA 1MJGA 2CZOA 3M3WA 1OCUA 3VKHA 4DCNC 2RAKA 4IKDA 4JNFA 4AZ9A 3EJPA 3KDRA 3HAIA 3BVUA 3HAJA 2X3WA 4KIKA 1I4DA 3CVRA 2N3KA 3QNJA 3Q0KA 3BVWA 2QKWA 2LXYA 3T48A 3LUIA 1SU8A 3B53X 1JQKA 1QX1A 2YIVX 4EZPA 1WDZA 2ETTA 4E3CA 3I04A 1SU6A 3I01A 4EZRA 1O7DB 3OWGA 4FZOA 2FICA 4WPEA 3CV5A 3VEBA 3QNIA 2D4CA 4HR1A 3SYVA 4FZPA 2PY6A 2YI8A 4BNEA 2OZNB 2F1BA 2WYIA 2EFLA 2X3VA 2GAFD 4HYBA 4IWOA 2GA9D 4JWCA 3BLBA 3D2EA 4P2JA 1GNLA 3D2FA 4R5KA 4H6IA 2YL6A 3IQ2A 1PS3A 4EZUA 2YIAA 5FLEX 2F1AA 3HPCX 1R34A 3D4YA 3C7NA 3QA8A 1DKXA 2V14A 2Z0NA 4IKBA 2AR5A 4F00A 1SUFA 4EZZA 4JNEA 5E84A 2YIBA 3Q84A 3ER8C 1TQSA 2RT6A 3D50A 4E81A 5C5BB 4D8JA 4NQIA 3DDGA 2OO2A 3HPBA 1I49A 2YKTA 2JNSA 1R5EA 3BUIA 3DYTA 2Q12A 4R5JA 2RAIA 4JN4A 4IM3A 3RV1A 2GF4A 2O0I1 1HXKA 4UDYX 3DX2A 3DPPA 1TQTA 3T49A 1OCSA 1KMDA 2ALWA 3DX4A 1KQ6A 3DX3A 2KHOA 4EZWA 2NCZA 3D52A 4PO2A 3HAHA 1GNTA 1GN9A 3D51A 4ON3A 3BUBA 1U00A 3CKDA 3O3MB 3CZSA 2X3XA 3OK8A 3ERCC 4AVMA 4M0MA 3LMFA 3DPOA 1E1DA 4AZHA 5FIGA 4AKVA 3A98A 1ZYLA 4WPCA 1X04A 2CSKA 3EJQA 3KAVA 1URUA 2D1LA 3ZEDA 4ATMA 2F7RA 3O3OB 2LM0A 4EZVA 1H6HA 2OW7A 2YL8A 4JLCA 2ND1A 2Z8YA 4P2IA 3OHXM 3ACOA 1X03A 4IWPA 4AZ6A 4BGJA 2ND0A 3DDFA 2WWEA 2F7QA 4IM0A 5C5BA 4AZCB
chains in the Genus database with same CATH topology
3DYTA 2Q12A 2I4KA 3LUIA 2RAIA 1XTEA 1XTNA 1ZWWA 3P0CA 3CAZA 4I1QA 1WDZA 2V6VA 1Y2OA 2ETTA 2DYBA 2YPSA 2ELBA 2C08A 1OCSA 1KMDA 3LLLA 1KQ6A 2FICA 4WPEA 4OXWA 3QNIA 4PQOA 2D4CA 3G9GA 3HAHA 3QE6A 3SYVA 4HASA 2REAA 2Z0VA 2Z0OA 4BNEA 2V0OA 4FZSA 3QWEA 4ON3A 3FOGA 2X3XA 2EFLA 2X3VA 4DYLA 3ABHA 3OK8A 4P2JA 3PLTA 1I4LA 1O7KA 3IQ2A 4AVMA 4PQPA 3HPCX 4AKVA 3SOGA 4WPCA 1X04A 4IKBB 2CSKA 2Q13A 2L73A 4PZGA 2V14A 2IWLX 2Z0NA 1URUA 2REDA 4IKBA 2D1LA 4ATMA 2AR5A 2CZOA 3M3WA 1OCUA 4DCNC 2RAKA 1H6HA 4IKDA 4AZ9A 3HAIA 4H8SA 2RAJA 3Q84A 4P2IA 2EFKA 3HAJA 3ACOA 2X3WA 3I2WA 4NSWA 1GD5A 1X03A 1I4DA 5C5BB 4NQIA 4BGJA 3HPBA 2WWEA 3Q0KA 1I49A 2YKTA 1I4TA 5C5BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYT A;  2Q12 A;  2I4K A;  3LUI A;  2RAI A;  1XTE A;  1XTN A;  1ZWW A;  3P0C A;  3CAZ A;  4I1Q A;  1WDZ A;  2V6V A;  1Y2O A;  2ETT A;  2DYB A;  2YPS A;  2ELB A;  2C08 A;  1OCS A;  1KMD A;  3LLL A;  1KQ6 A;  2FIC A;  4WPE A;  4OXW A;  3QNI A;  4PQO A;  2D4C A;  3G9G A;  3HAH A;  3QE6 A;  3SYV A;  4HAS A;  2REA A;  2Z0V A;  2Z0O A;  4BNE A;  2V0O A;  4FZS A;  3QWE A;  4ON3 A;  3FOG A;  2X3X A;  2EFL A;  2X3V A;  4DYL A;  3ABH A;  3OK8 A;  4P2J A;  3PLT A;  1I4L A;  1O7K A;  3IQ2 A;  4AVM A;  4PQP A;  3HPC X;  4AKV A;  3SOG A;  4WPC A;  1X04 A;  4IKB B;  2CSK A;  2Q13 A;  2L73 A;  4PZG A;  2V14 A;  2IWL X;  2Z0N A;  1URU A;  2RED A;  4IKB A;  2D1L A;  4ATM A;  2AR5 A;  2CZO A;  3M3W A;  1OCU A;  4DCN C;  2RAK A;  1H6H A;  4IKD A;  4AZ9 A;  3HAI A;  4H8S A;  2RAJ A;  3Q84 A;  4P2I A;  2EFK A;  3HAJ A;  3ACO A;  2X3W A;  3I2W A;  4NSW A;  1GD5 A;  1X03 A;  1I4D A;  5C5B B;  4NQI A;  4BGJ A;  3HPB A;  2WWE A;  3Q0K A;  1I49 A;  2YKT A;  1I4T A;  5C5B A; 
#chains in the Genus database with same CATH topology
 3CZN A;  3O3N B;  1XTE A;  1XTN A;  2QXL A;  1TQW A;  3T46 A;  3D4Z A;  4IWQ A;  1ZWW A;  4B9Q A;  1HTY A;  3LVT A;  2YLA A;  2EWF A;  3CAZ A;  4R5L A;  4JWE A;  3EJT A;  2ELB A;  2C08 A;  4UDX X;  1OA1 A;  4R5G A;  3LLL A;  3ER9 B;  4AZI A;  4PQO A;  3G9G A;  2F18 A;  4HAS A;  3EJR A;  2X5C A;  2Z0V A;  4R5I A;  1E9V A;  2Z0O A;  1OA0 A;  2V0O A;  3EJU A;  1QWU A;  3QWE A;  3T47 A;  4AZB A;  3BVX A;  2PMR A;  2MI7 A;  1DKZ A;  4FM3 A;  3ABH A;  2JNK A;  1I4L A;  3I39 X;  4AZ7 A;  1W9M A;  3VEA A;  2YI9 A;  2WYH A;  2QFF A;  4PQP A;  3L3O M;  2Q13 A;  2EX3 B;  2IWL X;  2RED A;  3RV0 A;  5TKY A;  4IW0 A;  4EZQ A;  4EZX A;  4HY9 A;  1SU7 A;  4JL9 A;  2F7P A;  3T4A G;  1QWN A;  3L3P A;  4KIK B;  2OBM A;  2OBL A;  1OAO A;  4H8S A;  2RAJ A;  4EZN A;  3RPM A;  2EFK A;  3BUQ A;  3I2W A;  4NSW A;  1GD5 A;  2F7O A;  4NPH A;  2ZXQ A;  3DPQ A;  3BUD A;  4G6Q A;  1HWW A;  1YWM A;  4EZT A;  1I4T A;  1DKY A;  2YL5 A;  2FYV A;  2I4K A;  4EZO A;  4EZY A;  1TQU A;  1UPX A;  3DX1 A;  4AZC A;  2OW6 A;  3P0C A;  3BVV A;  3KAW A;  4I1Q A;  3BVT A;  2V6V A;  1Y2O A;  2DYB A;  2YPS A;  3DX0 A;  4AZG A;  4HR1 B;  4OXW A;  3B51 X;  1O7D C;  1LQ7 A;  3F7W A;  3QE6 A;  5KBP A;  2REA A;  4AZ5 A;  4JWI A;  4FZS A;  1TQV A;  4F01 A;  3FOG A;  3UIT A;  2WIN M;  4JWD A;  4DYL A;  3BUP A;  3B52 X;  3PLT A;  1O7K A;  1E2U A;  4EZS A;  3EJS A;  3FD9 A;  4H6H A;  3SOG A;  4IKB B;  1R33 A;  4IM2 A;  3GI7 A;  2L73 A;  2YL9 A;  4PZG A;  2YLL A;  1MJG A;  2CZO A;  3M3W A;  1OCU A;  3VKH A;  4DCN C;  2RAK A;  4IKD A;  4JNF A;  4AZ9 A;  3EJP A;  3KDR A;  3HAI A;  3BVU A;  3HAJ A;  2X3W A;  4KIK A;  1I4D A;  3CVR A;  2N3K A;  3QNJ A;  3Q0K A;  3BVW A;  2QKW A;  2LXY A;  3T48 A;  3LUI A;  1SU8 A;  3B53 X;  1JQK A;  1QX1 A;  2YIV X;  4EZP A;  1WDZ A;  2ETT A;  4E3C A;  3I04 A;  1SU6 A;  3I01 A;  4EZR A;  1O7D B;  3OWG A;  4FZO A;  2FIC A;  4WPE A;  3CV5 A;  3VEB A;  3QNI A;  2D4C A;  4HR1 A;  3SYV A;  4FZP A;  2PY6 A;  2YI8 A;  4BNE A;  2OZN B;  2F1B A;  2WYI A;  2EFL A;  2X3V A;  2GAF D;  4HYB A;  4IWO A;  2GA9 D;  4JWC A;  3BLB A;  3D2E A;  4P2J A;  1GNL A;  3D2F A;  4R5K A;  4H6I A;  2YL6 A;  3IQ2 A;  1PS3 A;  4EZU A;  2YIA A;  5FLE X;  2F1A A;  3HPC X;  1R34 A;  3D4Y A;  3C7N A;  3QA8 A;  1DKX A;  2V14 A;  2Z0N A;  4IKB A;  2AR5 A;  4F00 A;  1SUF A;  4EZZ A;  4JNE A;  5E84 A;  2YIB A;  3Q84 A;  3ER8 C;  1TQS A;  2RT6 A;  3D50 A;  4E81 A;  5C5B B;  4D8J A;  4NQI A;  3DDG A;  2OO2 A;  3HPB A;  1I49 A;  2YKT A;  2JNS A;  1R5E A;  3BUI A;  3DYT A;  2Q12 A;  4R5J A;  2RAI A;  4JN4 A;  4IM3 A;  3RV1 A;  2GF4 A;  2O0I 1;  1HXK A;  4UDY X;  3DX2 A;  3DPP A;  1TQT A;  3T49 A;  1OCS A;  1KMD A;  2ALW A;  3DX4 A;  1KQ6 A;  3DX3 A;  2KHO A;  4EZW A;  2NCZ A;  3D52 A;  4PO2 A;  3HAH A;  1GNT A;  1GN9 A;  3D51 A;  4ON3 A;  3BUB A;  1U00 A;  3CKD A;  3O3M B;  3CZS A;  2X3X A;  3OK8 A;  3ERC C;  4AVM A;  4M0M A;  3LMF A;  3DPO A;  1E1D A;  4AZH A;  5FIG A;  4AKV A;  3A98 A;  1ZYL A;  4WPC A;  1X04 A;  2CSK A;  3EJQ A;  3KAV A;  1URU A;  2D1L A;  3ZED A;  4ATM A;  2F7R A;  3O3O B;  2LM0 A;  4EZV A;  1H6H A;  2OW7 A;  2YL8 A;  4JLC A;  2ND1 A;  2Z8Y A;  4P2I A;  3OHX M;  3ACO A;  1X03 A;  4IWP A;  4AZ6 A;  4BGJ A;  2ND0 A;  3DDF A;  2WWE A;  2F7Q A;  4IM0 A;  5C5B A;  4AZC B; 
#chains in the Genus database with same CATH homology
 3DYT A;  2Q12 A;  2I4K A;  3LUI A;  2RAI A;  1XTE A;  1XTN A;  1ZWW A;  3P0C A;  3CAZ A;  4I1Q A;  1WDZ A;  2V6V A;  1Y2O A;  2ETT A;  2DYB A;  2YPS A;  2ELB A;  2C08 A;  1OCS A;  1KMD A;  3LLL A;  1KQ6 A;  2FIC A;  4WPE A;  4OXW A;  3QNI A;  4PQO A;  2D4C A;  3G9G A;  3HAH A;  3QE6 A;  3SYV A;  4HAS A;  2REA A;  2Z0V A;  2Z0O A;  4BNE A;  2V0O A;  4FZS A;  3QWE A;  4ON3 A;  3FOG A;  2X3X A;  2EFL A;  2X3V A;  4DYL A;  3ABH A;  3OK8 A;  4P2J A;  3PLT A;  1I4L A;  1O7K A;  3IQ2 A;  4AVM A;  4PQP A;  3HPC X;  4AKV A;  3SOG A;  4WPC A;  1X04 A;  4IKB B;  2CSK A;  2Q13 A;  2L73 A;  4PZG A;  2V14 A;  2IWL X;  2Z0N A;  1URU A;  2RED A;  4IKB A;  2D1L A;  4ATM A;  2AR5 A;  2CZO A;  3M3W A;  1OCU A;  4DCN C;  2RAK A;  1H6H A;  4IKD A;  4AZ9 A;  3HAI A;  4H8S A;  2RAJ A;  3Q84 A;  4P2I A;  2EFK A;  3HAJ A;  3ACO A;  2X3W A;  3I2W A;  4NSW A;  1GD5 A;  1X03 A;  1I4D A;  5C5B B;  4NQI A;  4BGJ A;  3HPB A;  2WWE A;  3Q0K A;  1I49 A;  2YKT A;  1I4T A;  5C5B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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