2RAKA

Pi(3)p bound px-bar membrane remodeling unit of sorting nexin 9
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
382
structure length
382
Chain Sequence
PGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The PX-BAR membrane-remodeling unit of sorting nexin 9
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Sorting nexin-9
total genus 128
structure length 382
sequence length 382
ec nomenclature
pdb deposition date 2007-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2rakA03
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2rakA02
4PZGA 2ETTA 2L73A 2Z0VA 2EFKA 4ON3A 2D4CA 2X3VA 2YPSA 2C08A 2YKTA 2CSKA 1OCUA 1ZWWA 1I4TA 1I49A 2REAA 3ABHA 5C5BA 4DYLA 4FZSA 2I4KA 4I1QA 3SYVA 3HAHA 4BNEA 4OXWA 3FOGA 4P2IA 4WPCA 1GD5A 4IKBB 2X3WA 2IWLX 2REDA 3G9GA 4P2JA 1WDZA 1I4LA 2FICA 3HAIA 4HASA 3QNIA 3CAZA 3M3WA 2X3XA 3HAJA 2V6VA 4NQIA 2V0OA 1XTNA 4WPEA 3I2WA 4BGJA 2Z0OA 2AR5A 3Q0KA 2D1LA 3SOGA 2RAKA 1KMDA 4ATMA 3LLLA 4NSWA 2CZOA 4AKVA 3DYTA 3Q84A 4IKBA 1OCSA 2V14A 1I4DA 3P0CA 2DYBA 1X04A 2ELBA 2EFLA 4AZ9A 3QWEA 3PLTA 1XTEA 5C5BB 3ACOA 1X03A 4PQOA 2RAIA 3LUIA 1URUA 4AVMA 4PQPA 3HPCX 2RAJA 4DCNC 3QE6A 4IKDA 2Z0NA 2WWEA 4H8SA 1Y2OA 1O7KA 3IQ2A 3HPBA 1H6HA 3OK8A 1KQ6A 2Q13A 2Q12A
chains in the Genus database with same CATH superfamily
3T47A 1SU8A 2ZXQA 2F1AA 2NCZA 1TQTA 2EFKA 4ON3A 2D4CA 4AZGA 3KDRA 2YPSA 2C08A 2CSKA 2PMRA 1OCUA 1W9MA 4JWCA 1SU6A 4IM3A 2YL5A 2F7QA 2QXLA 3VEBA 1PS3A 4BNEA 3DX1A 4IWOA 2KHOA 3I04A 2IWLX 3OWGA 4IW0A 4HASA 3QA8A 2Z8YA 3EJQA 3RV1A 3B52X 4EZRA 3B53X 2JNKA 2YIVX 3F7WA 3T46A 4R5JA 4AZ5A 3SOGA 2RAKA 1KMDA 1DKYA 3LLLA 1O7DC 4F01A 1OCSA 3FD9A 3CVRA 4AZ9A 4JWIA 5C5BB 3ACOA 4PQOA 1OA0A 4AVMA 4E81A 2RAJA 3CZSA 1R5EA 3I01A 4E3CA 4JWDA 2OBMA 3QE6A 4IKDA 4IWPA 3O3MB 4H8SA 1O7KA 2OZNB 1H6HA 2N3KA 3VKHA 4EZTA 2EX3B 3EJTA 3C7NA 2Q13A 2YI8A 4JL9A 2L73A 2Z0VA 5E84A 1OA1A 3T48A 3DPOA 2YL6A 1I4TA 1I49A 5C5BA 3BLBA 3BVTA 3BVUA 1QWUA 3HAHA 3O3NB 2WYHA 3LVTA 4OXWA 3D50A 3T49A 4P2IA 1DKZA 4HYBA 3GI7A 2GA9D 4HY9A 3CKDA 3A98A 2REDA 4P2JA 1WDZA 3DPPA 2F7PA 4FZPA 3OHXM 2YL8A 4JN4A 1ZYLA 4R5LA 4PO2A 2ALWA 3HAJA 3L3PA 2ND1A 2V0OA 3BVVA 4EZPA 4EZWA 2F1BA 4EZQA 2YLAA 4AZ7A 1HWWA 3ER9B 1SU7A 4ATMA 2YLLA 1MJGA 4AZ6A 3CZNA 3D4YA 3EJSA 4AKVA 1JQKA 3DYTA 1I4DA 3P0CA 2MI7A 2ELBA 1E1DA 4H6IA 3BUBA 3KAVA 3PLTA 3D52A 4R5IA 1X03A 3DX4A 1DKXA 4AZCA 4F00A 4HR1A 5FIGA 2YI9A 3BVXA 2LXYA 1LQ7A 1Y2OA 3BVWA 4G6QA 3OK8A 1X04A 3EJRA 3CV5A 2YL9A 4PZGA 2ETTA 4D8JA 4JNFA 4EZXA 4EZNA 1HXKA 1YWMA 3KAWA 2YKTA 2OO2A 1TQSA 4EZZA 3ABHA 4FZSA 3DX0A 1UPXA 3ZEDA 3EJUA 2LM0A 3FOGA 3T4AG 1GD5A 1TQWA 2FYVA 4IKBB 3ERCC 4B9QA 4IM2A 1GNLA 2WYIA 4JWEA 2OBLA 3HAIA 1E9VA 3D51A 3CAZA 4IWQA 1SUFA 4H6HA 4EZUA 2ND0A 4UDYX 4NQIA 4FZOA 1XTNA 3I2WA 4BGJA 2QKWA 2Z0OA 3B51X 3BUPA 3Q0KA 1U00A 2OW6A 3Q84A 4IKBA 4EZVA 2X5CA 2DYBA 4KIKA 2EFLA 4AZCB 2F7RA 4AZIA 1GN9A 3RPMA 4HR1B 1R33A 2QFFA 3QWEA 1XTEA 2RAIA 3LUIA 2GF4A 4PQPA 4DCNC 3RV0A 2Z0NA 3IQ2A 3LMFA 3HPBA 5FLEX 3BUDA 3BUQA 4R5GA 3EJPA 2X3VA 4JNEA 4M0MA 3DPQA 3VEAA 3UITA 2F7OA 1ZWWA 2REAA 4DYLA 3DDFA 2I4KA 1TQVA 4I1QA 3SYVA 2PY6A 1GNTA 4WPCA 3DDGA 3ER8C 2O0I1 1HTYA 2X3WA 2F18A 3QNJA 3G9GA 4AZHA 2YIAA 1I4LA 3DX2A 4UDXX 2FICA 3BUIA 1QWNA 3D2FA 3D2EA 4JLCA 3QNIA 2RT6A 1R34A 4AZBA 4IM0A 3M3WA 2X3XA 2V6VA 3D4ZA 4EZSA 4WPEA 1O7DB 2AR5A 5TKYA 2D1LA 2WINM 4KIKB 4EZOA 1TQUA 1OAOA 2CZOA 4NSWA 4R5KA 2V14A 2YIBA 1QX1A 2OW7A 5KBPA 2EWFA 1E2UA 1URUA 4NPHA 2GAFD 3HPCX 2JNSA 3I39X 2WWEA 3O3OB 3L3OM 4EZYA 4FM3A 3DX3A 1KQ6A 2Q12A
chains in the Genus database with same CATH topology
4PZGA 2ETTA 2L73A 2Z0VA 2EFKA 4ON3A 2D4CA 2X3VA 2YPSA 2C08A 2YKTA 2CSKA 1OCUA 1ZWWA 1I4TA 1I49A 2REAA 3ABHA 5C5BA 4DYLA 4FZSA 2I4KA 4I1QA 3SYVA 3HAHA 4BNEA 4OXWA 3FOGA 4P2IA 4WPCA 1GD5A 4IKBB 2X3WA 2IWLX 2REDA 3G9GA 4P2JA 1WDZA 1I4LA 2FICA 3HAIA 4HASA 3QNIA 3CAZA 3M3WA 2X3XA 3HAJA 2V6VA 4NQIA 2V0OA 1XTNA 4WPEA 3I2WA 4BGJA 2Z0OA 2AR5A 3Q0KA 2D1LA 3SOGA 2RAKA 1KMDA 4ATMA 3LLLA 4NSWA 2CZOA 4AKVA 3DYTA 3Q84A 4IKBA 1OCSA 2V14A 1I4DA 3P0CA 2DYBA 1X04A 2ELBA 2EFLA 4AZ9A 3QWEA 3PLTA 1XTEA 5C5BB 3ACOA 1X03A 4PQOA 2RAIA 3LUIA 1URUA 4AVMA 4PQPA 3HPCX 2RAJA 4DCNC 3QE6A 4IKDA 2Z0NA 2WWEA 4H8SA 1Y2OA 1O7KA 3IQ2A 3HPBA 1H6HA 3OK8A 1KQ6A 2Q13A 2Q12A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PZG A;  2ETT A;  2L73 A;  2Z0V A;  2EFK A;  4ON3 A;  2D4C A;  2X3V A;  2YPS A;  2C08 A;  2YKT A;  2CSK A;  1OCU A;  1ZWW A;  1I4T A;  1I49 A;  2REA A;  3ABH A;  5C5B A;  4DYL A;  4FZS A;  2I4K A;  4I1Q A;  3SYV A;  3HAH A;  4BNE A;  4OXW A;  3FOG A;  4P2I A;  4WPC A;  1GD5 A;  4IKB B;  2X3W A;  2IWL X;  2RED A;  3G9G A;  4P2J A;  1WDZ A;  1I4L A;  2FIC A;  3HAI A;  4HAS A;  3QNI A;  3CAZ A;  3M3W A;  2X3X A;  3HAJ A;  2V6V A;  4NQI A;  2V0O A;  1XTN A;  4WPE A;  3I2W A;  4BGJ A;  2Z0O A;  2AR5 A;  3Q0K A;  2D1L A;  3SOG A;  2RAK A;  1KMD A;  4ATM A;  3LLL A;  4NSW A;  2CZO A;  4AKV A;  3DYT A;  3Q84 A;  4IKB A;  1OCS A;  2V14 A;  1I4D A;  3P0C A;  2DYB A;  1X04 A;  2ELB A;  2EFL A;  4AZ9 A;  3QWE A;  3PLT A;  1XTE A;  5C5B B;  3ACO A;  1X03 A;  4PQO A;  2RAI A;  3LUI A;  1URU A;  4AVM A;  4PQP A;  3HPC X;  2RAJ A;  4DCN C;  3QE6 A;  4IKD A;  2Z0N A;  2WWE A;  4H8S A;  1Y2O A;  1O7K A;  3IQ2 A;  3HPB A;  1H6H A;  3OK8 A;  1KQ6 A;  2Q13 A;  2Q12 A; 
#chains in the Genus database with same CATH topology
 3T47 A;  1SU8 A;  2ZXQ A;  2F1A A;  2NCZ A;  1TQT A;  2EFK A;  4ON3 A;  2D4C A;  4AZG A;  3KDR A;  2YPS A;  2C08 A;  2CSK A;  2PMR A;  1OCU A;  1W9M A;  4JWC A;  1SU6 A;  4IM3 A;  2YL5 A;  2F7Q A;  2QXL A;  3VEB A;  1PS3 A;  4BNE A;  3DX1 A;  4IWO A;  2KHO A;  3I04 A;  2IWL X;  3OWG A;  4IW0 A;  4HAS A;  3QA8 A;  2Z8Y A;  3EJQ A;  3RV1 A;  3B52 X;  4EZR A;  3B53 X;  2JNK A;  2YIV X;  3F7W A;  3T46 A;  4R5J A;  4AZ5 A;  3SOG A;  2RAK A;  1KMD A;  1DKY A;  3LLL A;  1O7D C;  4F01 A;  1OCS A;  3FD9 A;  3CVR A;  4AZ9 A;  4JWI A;  5C5B B;  3ACO A;  4PQO A;  1OA0 A;  4AVM A;  4E81 A;  2RAJ A;  3CZS A;  1R5E A;  3I01 A;  4E3C A;  4JWD A;  2OBM A;  3QE6 A;  4IKD A;  4IWP A;  3O3M B;  4H8S A;  1O7K A;  2OZN B;  1H6H A;  2N3K A;  3VKH A;  4EZT A;  2EX3 B;  3EJT A;  3C7N A;  2Q13 A;  2YI8 A;  4JL9 A;  2L73 A;  2Z0V A;  5E84 A;  1OA1 A;  3T48 A;  3DPO A;  2YL6 A;  1I4T A;  1I49 A;  5C5B A;  3BLB A;  3BVT A;  3BVU A;  1QWU A;  3HAH A;  3O3N B;  2WYH A;  3LVT A;  4OXW A;  3D50 A;  3T49 A;  4P2I A;  1DKZ A;  4HYB A;  3GI7 A;  2GA9 D;  4HY9 A;  3CKD A;  3A98 A;  2RED A;  4P2J A;  1WDZ A;  3DPP A;  2F7P A;  4FZP A;  3OHX M;  2YL8 A;  4JN4 A;  1ZYL A;  4R5L A;  4PO2 A;  2ALW A;  3HAJ A;  3L3P A;  2ND1 A;  2V0O A;  3BVV A;  4EZP A;  4EZW A;  2F1B A;  4EZQ A;  2YLA A;  4AZ7 A;  1HWW A;  3ER9 B;  1SU7 A;  4ATM A;  2YLL A;  1MJG A;  4AZ6 A;  3CZN A;  3D4Y A;  3EJS A;  4AKV A;  1JQK A;  3DYT A;  1I4D A;  3P0C A;  2MI7 A;  2ELB A;  1E1D A;  4H6I A;  3BUB A;  3KAV A;  3PLT A;  3D52 A;  4R5I A;  1X03 A;  3DX4 A;  1DKX A;  4AZC A;  4F00 A;  4HR1 A;  5FIG A;  2YI9 A;  3BVX A;  2LXY A;  1LQ7 A;  1Y2O A;  3BVW A;  4G6Q A;  3OK8 A;  1X04 A;  3EJR A;  3CV5 A;  2YL9 A;  4PZG A;  2ETT A;  4D8J A;  4JNF A;  4EZX A;  4EZN A;  1HXK A;  1YWM A;  3KAW A;  2YKT A;  2OO2 A;  1TQS A;  4EZZ A;  3ABH A;  4FZS A;  3DX0 A;  1UPX A;  3ZED A;  3EJU A;  2LM0 A;  3FOG A;  3T4A G;  1GD5 A;  1TQW A;  2FYV A;  4IKB B;  3ERC C;  4B9Q A;  4IM2 A;  1GNL A;  2WYI A;  4JWE A;  2OBL A;  3HAI A;  1E9V A;  3D51 A;  3CAZ A;  4IWQ A;  1SUF A;  4H6H A;  4EZU A;  2ND0 A;  4UDY X;  4NQI A;  4FZO A;  1XTN A;  3I2W A;  4BGJ A;  2QKW A;  2Z0O A;  3B51 X;  3BUP A;  3Q0K A;  1U00 A;  2OW6 A;  3Q84 A;  4IKB A;  4EZV A;  2X5C A;  2DYB A;  4KIK A;  2EFL A;  4AZC B;  2F7R A;  4AZI A;  1GN9 A;  3RPM A;  4HR1 B;  1R33 A;  2QFF A;  3QWE A;  1XTE A;  2RAI A;  3LUI A;  2GF4 A;  4PQP A;  4DCN C;  3RV0 A;  2Z0N A;  3IQ2 A;  3LMF A;  3HPB A;  5FLE X;  3BUD A;  3BUQ A;  4R5G A;  3EJP A;  2X3V A;  4JNE A;  4M0M A;  3DPQ A;  3VEA A;  3UIT A;  2F7O A;  1ZWW A;  2REA A;  4DYL A;  3DDF A;  2I4K A;  1TQV A;  4I1Q A;  3SYV A;  2PY6 A;  1GNT A;  4WPC A;  3DDG A;  3ER8 C;  2O0I 1;  1HTY A;  2X3W A;  2F18 A;  3QNJ A;  3G9G A;  4AZH A;  2YIA A;  1I4L A;  3DX2 A;  4UDX X;  2FIC A;  3BUI A;  1QWN A;  3D2F A;  3D2E A;  4JLC A;  3QNI A;  2RT6 A;  1R34 A;  4AZB A;  4IM0 A;  3M3W A;  2X3X A;  2V6V A;  3D4Z A;  4EZS A;  4WPE A;  1O7D B;  2AR5 A;  5TKY A;  2D1L A;  2WIN M;  4KIK B;  4EZO A;  1TQU A;  1OAO A;  2CZO A;  4NSW A;  4R5K A;  2V14 A;  2YIB A;  1QX1 A;  2OW7 A;  5KBP A;  2EWF A;  1E2U A;  1URU A;  4NPH A;  2GAF D;  3HPC X;  2JNS A;  3I39 X;  2WWE A;  3O3O B;  3L3O M;  4EZY A;  4FM3 A;  3DX3 A;  1KQ6 A;  2Q12 A; 
#chains in the Genus database with same CATH homology
 4PZG A;  2ETT A;  2L73 A;  2Z0V A;  2EFK A;  4ON3 A;  2D4C A;  2X3V A;  2YPS A;  2C08 A;  2YKT A;  2CSK A;  1OCU A;  1ZWW A;  1I4T A;  1I49 A;  2REA A;  3ABH A;  5C5B A;  4DYL A;  4FZS A;  2I4K A;  4I1Q A;  3SYV A;  3HAH A;  4BNE A;  4OXW A;  3FOG A;  4P2I A;  4WPC A;  1GD5 A;  4IKB B;  2X3W A;  2IWL X;  2RED A;  3G9G A;  4P2J A;  1WDZ A;  1I4L A;  2FIC A;  3HAI A;  4HAS A;  3QNI A;  3CAZ A;  3M3W A;  2X3X A;  3HAJ A;  2V6V A;  4NQI A;  2V0O A;  1XTN A;  4WPE A;  3I2W A;  4BGJ A;  2Z0O A;  2AR5 A;  3Q0K A;  2D1L A;  3SOG A;  2RAK A;  1KMD A;  4ATM A;  3LLL A;  4NSW A;  2CZO A;  4AKV A;  3DYT A;  3Q84 A;  4IKB A;  1OCS A;  2V14 A;  1I4D A;  3P0C A;  2DYB A;  1X04 A;  2ELB A;  2EFL A;  4AZ9 A;  3QWE A;  3PLT A;  1XTE A;  5C5B B;  3ACO A;  1X03 A;  4PQO A;  2RAI A;  3LUI A;  1URU A;  4AVM A;  4PQP A;  3HPC X;  2RAJ A;  4DCN C;  3QE6 A;  4IKD A;  2Z0N A;  2WWE A;  4H8S A;  1Y2O A;  1O7K A;  3IQ2 A;  3HPB A;  1H6H A;  3OK8 A;  1KQ6 A;  2Q13 A;  2Q12 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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