4AKVA

Crystal structure of human sorting nexin 33 (snx33)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
363
structure length
345
Chain Sequence
MYSIEMGPRGPQWKANPHPFACSVEDPISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Human Sorting Nexin 33
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SORTING NEXIN-33
total genus 140
structure length 345
sequence length 363
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4akvA02
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4akvA01
3Q84A 2CSKA 3LUIA 2Z0VA 4PQOA 2EFKA 1Y2OA 4OXWA 2I4KA 1URUA 2ELBA 4PQPA 4AVMA 1I49A 3HAJA 3FOGA 4IKBA 2WWEA 4AZ9A 2C08A 4ON3A 4I1QA 2EFLA 1WDZA 2RAJA 3IQ2A 2REDA 2V6VA 1O7KA 3ACOA 4NSWA 2Z0OA 4P2IA 4P2JA 1OCSA 1H6HA 4HASA 4BGJA 2YPSA 3DYTA 3SYVA 3SOGA 2V0OA 3HPCX 3LLLA 3Q0KA 5C5BA 3ABHA 3QWEA 4BNEA 3M3WA 1I4TA 1OCUA 1KMDA 4WPCA 3HAIA 2X3WA 1I4DA 4AKVA 4DCNC 1GD5A 4IKBB 2RAKA 4NQIA 4WPEA 2YKTA 2X3VA 1I4LA 1XTEA 3QNIA 4H8SA 3CAZA 2DYBA 2CZOA 2RAIA 1ZWWA 4ATMA 2D1LA 4DYLA 3PLTA 3P0CA 2AR5A 2Z0NA 2ETTA 1X04A 2Q12A 4FZSA 2IWLX 4PZGA 3QE6A 2D4CA 3G9GA 2Q13A 2FICA 5C5BB 4IKDA 3OK8A 2V14A 2L73A 3HPBA 1X03A 1KQ6A 2X3XA 2REAA 3I2WA 3HAHA 1XTNA
chains in the Genus database with same CATH superfamily
4JL9A 1QWUA 4AZ6A 4EZQA 2F1BA 4PQPA 3RV0A 3HAJA 2WWEA 4ON3A 3T47A 4UDXX 2EFLA 4HR1A 2Z8YA 4R5JA 2V6VA 2QFFA 3O3OB 1JQKA 1HXKA 1OCSA 2O0I1 2OO2A 4EZYA 3T4AG 2YL5A 2YPSA 1E1DA 3UITA 4KIKA 2V0OA 3HPCX 3LLLA 1U00A 1PS3A 4AZIA 3QWEA 1KMDA 3BVVA 5FIGA 4H6IA 2X3WA 3L3OM 2WYHA 4R5GA 2JNSA 1SU7A 4IKBB 3DX3A 1UPXA 3DX0A 2F7RA 2X3VA 3D51A 1I4LA 5E84A 1R5EA 3QNIA 3BVTA 3OWGA 2CZOA 1E9VA 4IW0A 2D1LA 2YI9A 4D8JA 3CV5A 4DYLA 2PMRA 3PLTA 1GNLA 3P0CA 3T46A 2AR5A 2YIBA 3T49A 4EZWA 4R5KA 3BUPA 4FZSA 2D4CA 3G9GA 3ER8C 1OA0A 3D2EA 3GI7A 5C5BB 4IKDA 3OK8A 3EJRA 2V14A 2L73A 1KQ6A 4F00A 2X3XA 3I2WA 3D50A 4JNEA 2LM0A 2CSKA 3LUIA 2OW6A 3I01A 2OBLA 3RV1A 3F7WA 4AVMA 1OAOA 3FOGA 4EZTA 3CZSA 2REDA 4G6QA 3I04A 3EJQA 3I39X 3VEAA 1R34A 2ALWA 2PY6A 4IWOA 2ND1A 2Z0OA 1DKZA 4P2JA 2YLLA 4IM2A 4AZ7A 4HR1B 3DYTA 2YLAA 4AZCB 3Q0KA 1DKXA 2WINM 3ABHA 4BNEA 1ZYLA 4F01A 2ND0A 3C7NA 4R5LA 4AKVA 4DCNC 1GD5A 4M0MA 4KIKB 3DDFA 1DKYA 4EZPA 1W9MA 2YL9A 4EZOA 4AZGA 1XTEA 1TQUA 3CAZA 2DYBA 4EZRA 3B53X 5FLEX 2X5CA 3CVRA 3FD9A 4B9QA 4ATMA 1O7DC 4IWQA 4JWIA 3KDRA 2QKWA 4PZGA 3ZEDA 1SU8A 4PO2A 5KBPA 2GAFD 2FYVA 4HYBA 1YWMA 1E2UA 3HPBA 2ZXQA 3Q84A 2Z0VA 4OXWA 2YL8A 2F1AA 2I4KA 4H6HA 2F7OA 3KAWA 3DPPA 3CZNA 4IKBA 4AZ9A 3ER9B 1QWNA 2C08A 2RAJA 1WDZA 3O3MB 4JN4A 3ACOA 2OZNB 4EZUA 3BLBA 4JNFA 4NSWA 4HASA 4BGJA 1HWWA 3KAVA 4EZXA 3DX2A 2GA9D 5TKYA 3O3NB 5C5BA 1OCUA 3BVUA 4WPCA 3EJSA 4JWDA 4NQIA 2YKTA 4R5IA 1SU6A 2QXLA 4H8SA 2F7PA 1TQTA 3DPQA 2NCZA 4FM3A 4IM0A 2JNKA 2RAIA 1ZWWA 3L3PA 3EJPA 2F7QA 2EX3B 2Z0NA 1GN9A 2ETTA 3CKDA 2Q12A 2N3KA 2IWLX 3QE6A 4AZHA 2Q13A 3DDGA 3VKHA 3BUDA 2F18A 3EJUA 2YIVX 4E81A 3BVWA 2KHOA 2MI7A 3BVXA 4AZCA 2LXYA 3HAHA 4PQOA 2EFKA 1O7DB 1Y2OA 4NPHA 4EZNA 1R33A 2OBMA 3B52X 3D2FA 1URUA 2ELBA 1OA1A 3D4YA 1I49A 4FZPA 3D52A 2RT6A 1TQVA 4AZ5A 4I1QA 3IQ2A 4FZOA 3DPOA 3RPMA 1GNTA 4AZBA 4EZSA 1O7KA 3DX1A 3BUBA 3DX4A 1LQ7A 4HY9A 4P2IA 1H6HA 2GF4A 3BUIA 1HTYA 3SYVA 3SOGA 3LMFA 2WYIA 1MJGA 1I4TA 3M3WA 3QA8A 3D4ZA 4JWCA 3HAIA 1I4DA 4E3CA 2RAKA 4WPEA 1SUFA 2YL6A 2YI8A 4IM3A 3EJTA 3VEBA 3B51X 1QX1A 4EZVA 4UDYX 3QNJA 1X04A 3T48A 2OW7A 3OHXM 4IWPA 4JWEA 3ERCC 4EZZA 2YIAA 4JLCA 2FICA 1TQSA 1TQWA 3A98A 1X03A 3LVTA 2REAA 3BUQA 2EWFA 1XTNA
chains in the Genus database with same CATH topology
3Q84A 2CSKA 3LUIA 2Z0VA 4PQOA 2EFKA 1Y2OA 4OXWA 2I4KA 1URUA 2ELBA 4PQPA 4AVMA 1I49A 3HAJA 3FOGA 4IKBA 2WWEA 4AZ9A 2C08A 4ON3A 4I1QA 2EFLA 1WDZA 2RAJA 3IQ2A 2REDA 2V6VA 1O7KA 3ACOA 4NSWA 2Z0OA 4P2IA 4P2JA 1OCSA 1H6HA 4HASA 4BGJA 2YPSA 3DYTA 3SYVA 3SOGA 2V0OA 3HPCX 3LLLA 3Q0KA 5C5BA 3ABHA 3QWEA 4BNEA 3M3WA 1I4TA 1OCUA 1KMDA 4WPCA 3HAIA 2X3WA 1I4DA 4AKVA 4DCNC 1GD5A 4IKBB 2RAKA 4NQIA 4WPEA 2YKTA 2X3VA 1I4LA 1XTEA 3QNIA 4H8SA 3CAZA 2DYBA 2CZOA 2RAIA 1ZWWA 4ATMA 2D1LA 4DYLA 3PLTA 3P0CA 2AR5A 2Z0NA 2ETTA 1X04A 2Q12A 4FZSA 2IWLX 4PZGA 3QE6A 2D4CA 3G9GA 2Q13A 2FICA 5C5BB 4IKDA 3OK8A 2V14A 2L73A 3HPBA 1X03A 1KQ6A 2X3XA 2REAA 3I2WA 3HAHA 1XTNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q84 A;  2CSK A;  3LUI A;  2Z0V A;  4PQO A;  2EFK A;  1Y2O A;  4OXW A;  2I4K A;  1URU A;  2ELB A;  4PQP A;  4AVM A;  1I49 A;  3HAJ A;  3FOG A;  4IKB A;  2WWE A;  4AZ9 A;  2C08 A;  4ON3 A;  4I1Q A;  2EFL A;  1WDZ A;  2RAJ A;  3IQ2 A;  2RED A;  2V6V A;  1O7K A;  3ACO A;  4NSW A;  2Z0O A;  4P2I A;  4P2J A;  1OCS A;  1H6H A;  4HAS A;  4BGJ A;  2YPS A;  3DYT A;  3SYV A;  3SOG A;  2V0O A;  3HPC X;  3LLL A;  3Q0K A;  5C5B A;  3ABH A;  3QWE A;  4BNE A;  3M3W A;  1I4T A;  1OCU A;  1KMD A;  4WPC A;  3HAI A;  2X3W A;  1I4D A;  4AKV A;  4DCN C;  1GD5 A;  4IKB B;  2RAK A;  4NQI A;  4WPE A;  2YKT A;  2X3V A;  1I4L A;  1XTE A;  3QNI A;  4H8S A;  3CAZ A;  2DYB A;  2CZO A;  2RAI A;  1ZWW A;  4ATM A;  2D1L A;  4DYL A;  3PLT A;  3P0C A;  2AR5 A;  2Z0N A;  2ETT A;  1X04 A;  2Q12 A;  4FZS A;  2IWL X;  4PZG A;  3QE6 A;  2D4C A;  3G9G A;  2Q13 A;  2FIC A;  5C5B B;  4IKD A;  3OK8 A;  2V14 A;  2L73 A;  3HPB A;  1X03 A;  1KQ6 A;  2X3X A;  2REA A;  3I2W A;  3HAH A;  1XTN A; 
#chains in the Genus database with same CATH topology
 4JL9 A;  1QWU A;  4AZ6 A;  4EZQ A;  2F1B A;  4PQP A;  3RV0 A;  3HAJ A;  2WWE A;  4ON3 A;  3T47 A;  4UDX X;  2EFL A;  4HR1 A;  2Z8Y A;  4R5J A;  2V6V A;  2QFF A;  3O3O B;  1JQK A;  1HXK A;  1OCS A;  2O0I 1;  2OO2 A;  4EZY A;  3T4A G;  2YL5 A;  2YPS A;  1E1D A;  3UIT A;  4KIK A;  2V0O A;  3HPC X;  3LLL A;  1U00 A;  1PS3 A;  4AZI A;  3QWE A;  1KMD A;  3BVV A;  5FIG A;  4H6I A;  2X3W A;  3L3O M;  2WYH A;  4R5G A;  2JNS A;  1SU7 A;  4IKB B;  3DX3 A;  1UPX A;  3DX0 A;  2F7R A;  2X3V A;  3D51 A;  1I4L A;  5E84 A;  1R5E A;  3QNI A;  3BVT A;  3OWG A;  2CZO A;  1E9V A;  4IW0 A;  2D1L A;  2YI9 A;  4D8J A;  3CV5 A;  4DYL A;  2PMR A;  3PLT A;  1GNL A;  3P0C A;  3T46 A;  2AR5 A;  2YIB A;  3T49 A;  4EZW A;  4R5K A;  3BUP A;  4FZS A;  2D4C A;  3G9G A;  3ER8 C;  1OA0 A;  3D2E A;  3GI7 A;  5C5B B;  4IKD A;  3OK8 A;  3EJR A;  2V14 A;  2L73 A;  1KQ6 A;  4F00 A;  2X3X A;  3I2W A;  3D50 A;  4JNE A;  2LM0 A;  2CSK A;  3LUI A;  2OW6 A;  3I01 A;  2OBL A;  3RV1 A;  3F7W A;  4AVM A;  1OAO A;  3FOG A;  4EZT A;  3CZS A;  2RED A;  4G6Q A;  3I04 A;  3EJQ A;  3I39 X;  3VEA A;  1R34 A;  2ALW A;  2PY6 A;  4IWO A;  2ND1 A;  2Z0O A;  1DKZ A;  4P2J A;  2YLL A;  4IM2 A;  4AZ7 A;  4HR1 B;  3DYT A;  2YLA A;  4AZC B;  3Q0K A;  1DKX A;  2WIN M;  3ABH A;  4BNE A;  1ZYL A;  4F01 A;  2ND0 A;  3C7N A;  4R5L A;  4AKV A;  4DCN C;  1GD5 A;  4M0M A;  4KIK B;  3DDF A;  1DKY A;  4EZP A;  1W9M A;  2YL9 A;  4EZO A;  4AZG A;  1XTE A;  1TQU A;  3CAZ A;  2DYB A;  4EZR A;  3B53 X;  5FLE X;  2X5C A;  3CVR A;  3FD9 A;  4B9Q A;  4ATM A;  1O7D C;  4IWQ A;  4JWI A;  3KDR A;  2QKW A;  4PZG A;  3ZED A;  1SU8 A;  4PO2 A;  5KBP A;  2GAF D;  2FYV A;  4HYB A;  1YWM A;  1E2U A;  3HPB A;  2ZXQ A;  3Q84 A;  2Z0V A;  4OXW A;  2YL8 A;  2F1A A;  2I4K A;  4H6H A;  2F7O A;  3KAW A;  3DPP A;  3CZN A;  4IKB A;  4AZ9 A;  3ER9 B;  1QWN A;  2C08 A;  2RAJ A;  1WDZ A;  3O3M B;  4JN4 A;  3ACO A;  2OZN B;  4EZU A;  3BLB A;  4JNF A;  4NSW A;  4HAS A;  4BGJ A;  1HWW A;  3KAV A;  4EZX A;  3DX2 A;  2GA9 D;  5TKY A;  3O3N B;  5C5B A;  1OCU A;  3BVU A;  4WPC A;  3EJS A;  4JWD A;  4NQI A;  2YKT A;  4R5I A;  1SU6 A;  2QXL A;  4H8S A;  2F7P A;  1TQT A;  3DPQ A;  2NCZ A;  4FM3 A;  4IM0 A;  2JNK A;  2RAI A;  1ZWW A;  3L3P A;  3EJP A;  2F7Q A;  2EX3 B;  2Z0N A;  1GN9 A;  2ETT A;  3CKD A;  2Q12 A;  2N3K A;  2IWL X;  3QE6 A;  4AZH A;  2Q13 A;  3DDG A;  3VKH A;  3BUD A;  2F18 A;  3EJU A;  2YIV X;  4E81 A;  3BVW A;  2KHO A;  2MI7 A;  3BVX A;  4AZC A;  2LXY A;  3HAH A;  4PQO A;  2EFK A;  1O7D B;  1Y2O A;  4NPH A;  4EZN A;  1R33 A;  2OBM A;  3B52 X;  3D2F A;  1URU A;  2ELB A;  1OA1 A;  3D4Y A;  1I49 A;  4FZP A;  3D52 A;  2RT6 A;  1TQV A;  4AZ5 A;  4I1Q A;  3IQ2 A;  4FZO A;  3DPO A;  3RPM A;  1GNT A;  4AZB A;  4EZS A;  1O7K A;  3DX1 A;  3BUB A;  3DX4 A;  1LQ7 A;  4HY9 A;  4P2I A;  1H6H A;  2GF4 A;  3BUI A;  1HTY A;  3SYV A;  3SOG A;  3LMF A;  2WYI A;  1MJG A;  1I4T A;  3M3W A;  3QA8 A;  3D4Z A;  4JWC A;  3HAI A;  1I4D A;  4E3C A;  2RAK A;  4WPE A;  1SUF A;  2YL6 A;  2YI8 A;  4IM3 A;  3EJT A;  3VEB A;  3B51 X;  1QX1 A;  4EZV A;  4UDY X;  3QNJ A;  1X04 A;  3T48 A;  2OW7 A;  3OHX M;  4IWP A;  4JWE A;  3ERC C;  4EZZ A;  2YIA A;  4JLC A;  2FIC A;  1TQS A;  1TQW A;  3A98 A;  1X03 A;  3LVT A;  2REA A;  3BUQ A;  2EWF A;  1XTN A; 
#chains in the Genus database with same CATH homology
 3Q84 A;  2CSK A;  3LUI A;  2Z0V A;  4PQO A;  2EFK A;  1Y2O A;  4OXW A;  2I4K A;  1URU A;  2ELB A;  4PQP A;  4AVM A;  1I49 A;  3HAJ A;  3FOG A;  4IKB A;  2WWE A;  4AZ9 A;  2C08 A;  4ON3 A;  4I1Q A;  2EFL A;  1WDZ A;  2RAJ A;  3IQ2 A;  2RED A;  2V6V A;  1O7K A;  3ACO A;  4NSW A;  2Z0O A;  4P2I A;  4P2J A;  1OCS A;  1H6H A;  4HAS A;  4BGJ A;  2YPS A;  3DYT A;  3SYV A;  3SOG A;  2V0O A;  3HPC X;  3LLL A;  3Q0K A;  5C5B A;  3ABH A;  3QWE A;  4BNE A;  3M3W A;  1I4T A;  1OCU A;  1KMD A;  4WPC A;  3HAI A;  2X3W A;  1I4D A;  4AKV A;  4DCN C;  1GD5 A;  4IKB B;  2RAK A;  4NQI A;  4WPE A;  2YKT A;  2X3V A;  1I4L A;  1XTE A;  3QNI A;  4H8S A;  3CAZ A;  2DYB A;  2CZO A;  2RAI A;  1ZWW A;  4ATM A;  2D1L A;  4DYL A;  3PLT A;  3P0C A;  2AR5 A;  2Z0N A;  2ETT A;  1X04 A;  2Q12 A;  4FZS A;  2IWL X;  4PZG A;  3QE6 A;  2D4C A;  3G9G A;  2Q13 A;  2FIC A;  5C5B B;  4IKD A;  3OK8 A;  2V14 A;  2L73 A;  3HPB A;  1X03 A;  1KQ6 A;  2X3X A;  2REA A;  3I2W A;  3HAH A;  1XTN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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