4AKVA

Crystal structure of human sorting nexin 33 (snx33)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
363
structure length
345
Chain Sequence
MYSIEMGPRGPQWKANPHPFACSVEDPISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Human Sorting Nexin 33
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SORTING NEXIN-33
total genus 140
structure length 345
sequence length 363
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4akvA02
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4akvA01
2CZOA 4P2IA 3P0CA 1GD5A 4IKBB 2Q12A 2AR5A 2EFKA 2V14A 2L73A 1Y2OA 3QWEA 2RAKA 2DYBA 3LUIA 1XTEA 3Q84A 4PZGA 3ABHA 3HAIA 3HAHA 3M3WA 4P2JA 3ACOA 2Z0VA 1I49A 1X04A 4BGJA 3IQ2A 3QE6A 2CSKA 1ZWWA 1URUA 1X03A 4AVMA 5C5BA 4HASA 1OCSA 2D4CA 2REDA 1KQ6A 4BNEA 2FICA 4NSWA 1OCUA 1I4TA 2Q13A 3FOGA 4IKBA 4I1QA 2Z0OA 2YPSA 3SOGA 3G9GA 2I4KA 3QNIA 2X3XA 4ON3A 3LLLA 2EFLA 4H8SA 4DCNC 1KMDA 2RAJA 3PLTA 2REAA 1I4DA 3CAZA 4WPCA 2YKTA 2RAIA 2WWEA 1XTNA 3I2WA 3HAJA 4PQPA 1I4LA 2Z0NA 4AKVA 4PQOA 4WPEA 1O7KA 4IKDA 4FZSA 4OXWA 4DYLA 3HPCX 2IWLX 2X3VA 3Q0KA 3DYTA 1H6HA 2C08A 2V6VA 3SYVA 1WDZA 2X3WA 3OK8A 2ELBA 4ATMA 3HPBA 4NQIA 2V0OA 2D1LA 4AZ9A 2ETTA 5C5BB
chains in the Genus database with same CATH superfamily
4HR1B 2CZOA 3P0CA 4IKBB 3I01A 2AR5A 1E9VA 3D50A 3EJTA 4E3CA 3RV1A 3QWEA 4EZSA 3B52X 3LUIA 1DKXA 2ND0A 3HAIA 3HAHA 3M3WA 4P2JA 3RPMA 1U00A 3DDFA 4R5KA 1SU6A 4EZYA 2CSKA 1URUA 3D52A 4HASA 1OCUA 4JLCA 3FOGA 4IKBA 1O7DB 4I1QA 2PMRA 2QKWA 3T46A 3G9GA 4ON3A 4B9QA 4H8SA 1KMDA 2OBLA 2REAA 2YKTA 3I39X 2OBMA 2EX3B 3DX2A 4PQPA 3ERCC 1TQUA 4IM2A 4M0MA 2Z0NA 4EZRA 4PQOA 4AZIA 4IKDA 4R5IA 3BUDA 2GAFD 4R5LA 1PS3A 3QA8A 2ND1A 3VEAA 3D4ZA 1H6HA 2O0I1 1WDZA 3OWGA 3DX1A 3OK8A 2X5CA 4EZPA 2YIBA 3HPBA 3DDGA 2YIVX 3DX4A 4AZ9A 3BUBA 1GNLA 4EZTA 3D4YA 2YLAA 2Q12A 2EFKA 2GA9D 4JWIA 2NCZA 1OAOA 1HWWA 3L3PA 2L73A 1Y2OA 3QNJA 1O7DC 1LQ7A 2DYBA 5KBPA 2QFFA 1GNTA 2YL6A 4IWQA 1SU8A 3CZNA 3C7NA 4EZUA 2Z0VA 4JNFA 1R5EA 4R5GA 4NPHA 2Z8YA 1ZWWA 3BVUA 3DX0A 1OCSA 2REDA 1R34A 4NSWA 3LMFA 3B51X 2Z0OA 3O3OB 4JN4A 2I4KA 2X3XA 3CV5A 3PLTA 2F7OA 4AZCA 3BUIA 2RAIA 2WWEA 1XTNA 3I2WA 4R5JA 3T49A 4EZNA 3EJQA 2JNSA 1I4LA 3KAWA 4HR1A 2YLLA 4EZXA 2RT6A 4JWDA 3ER8C 4KIKB 5FIGA 4FZSA 4OXWA 3FD9A 4AZ7A 2IWLX 3DPQA 3CKDA 3A98A 1TQVA 2WYHA 4EZWA 2X3WA 3BVXA 2OW7A 2F7RA 3RV0A 2V0OA 3BUQA 4H6IA 4AZ5A 5C5BB 4HY9A 3LVTA 3GI7A 4P2IA 1GD5A 1W9MA 4JNEA 1SU7A 4KIKA 3KAVA 3B53X 1ZYLA 3Q84A 3EJSA 4JL9A 5FLEX 4H6HA 1I49A 1X04A 3O3NB 3IQ2A 2PY6A 2YIAA 3D2EA 5C5BA 4IW0A 2YL5A 2D4CA 1KQ6A 4BNEA 1I4TA 2Q13A 2GF4A 2OO2A 4F00A 2WINM 4UDYX 4DCNC 4AZBA 3CAZA 3DX3A 3I04A 4EZVA 3HAJA 3F7WA 1MJGA 2LXYA 4JWCA 3ZEDA 2F1AA 4AKVA 2LM0A 2ALWA 3CZSA 4WPEA 3DPOA 3HPCX 3D51A 3VEBA 1JQKA 1TQTA 2C08A 2V6VA 3T48A 2MI7A 3KDRA 1E2UA 4IWPA 3D2FA 2YI8A 2JNKA 4ATMA 1E1DA 4NQIA 3L3OM 2D1LA 4FM3A 4AZHA 2ETTA 3EJPA 4UDXX 1R33A 3DPPA 2OZNB 1DKZA 2V14A 3CVRA 3ER9B 3BUPA 2RAKA 1XTEA 4PZGA 3ABHA 2F18A 4HYBA 1SUFA 2YI9A 1TQWA 3VKHA 4EZOA 4EZQA 3ACOA 5TKYA 4PO2A 4BGJA 3QE6A 3T47A 2N3KA 1X03A 4AVMA 1OA0A 4FZPA 4FZOA 3UITA 2WYIA 4IM0A 2FICA 1DKYA 2KHOA 2F7PA 4AZGA 2F7QA 2YPSA 4IM3A 3SOGA 4F01A 1QWUA 3QNIA 3LLLA 2EFLA 4JWEA 4AZ6A 3T4AG 2RAJA 3O3MB 1TQSA 1HXKA 1I4DA 4WPCA 3BLBA 4G6QA 1HTYA 4EZZA 2QXLA 5E84A 2OW6A 4E81A 3OHXM 2YL9A 2ZXQA 4D8JA 3BVWA 1UPXA 3BVTA 1YWMA 1QX1A 2EWFA 1O7KA 3BVVA 2F1BA 1QWNA 4DYLA 2X3VA 3Q0KA 3DYTA 3EJRA 3EJUA 3SYVA 4AZCB 2ELBA 2FYVA 1OA1A 1GN9A 2YL8A 4IWOA
chains in the Genus database with same CATH topology
2CZOA 4P2IA 3P0CA 1GD5A 4IKBB 2Q12A 2AR5A 2EFKA 2V14A 2L73A 1Y2OA 3QWEA 2RAKA 2DYBA 3LUIA 1XTEA 3Q84A 4PZGA 3ABHA 3HAIA 3HAHA 3M3WA 4P2JA 3ACOA 2Z0VA 1I49A 1X04A 4BGJA 3IQ2A 3QE6A 2CSKA 1ZWWA 1URUA 1X03A 4AVMA 5C5BA 4HASA 1OCSA 2D4CA 2REDA 1KQ6A 4BNEA 2FICA 4NSWA 1OCUA 1I4TA 2Q13A 3FOGA 4IKBA 4I1QA 2Z0OA 2YPSA 3SOGA 3G9GA 2I4KA 3QNIA 2X3XA 4ON3A 3LLLA 2EFLA 4H8SA 4DCNC 1KMDA 2RAJA 3PLTA 2REAA 1I4DA 3CAZA 4WPCA 2YKTA 2RAIA 2WWEA 1XTNA 3I2WA 3HAJA 4PQPA 1I4LA 2Z0NA 4AKVA 4PQOA 4WPEA 1O7KA 4IKDA 4FZSA 4OXWA 4DYLA 3HPCX 2IWLX 2X3VA 3Q0KA 3DYTA 1H6HA 2C08A 2V6VA 3SYVA 1WDZA 2X3WA 3OK8A 2ELBA 4ATMA 3HPBA 4NQIA 2V0OA 2D1LA 4AZ9A 2ETTA 5C5BB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CZO A;  4P2I A;  3P0C A;  1GD5 A;  4IKB B;  2Q12 A;  2AR5 A;  2EFK A;  2V14 A;  2L73 A;  1Y2O A;  3QWE A;  2RAK A;  2DYB A;  3LUI A;  1XTE A;  3Q84 A;  4PZG A;  3ABH A;  3HAI A;  3HAH A;  3M3W A;  4P2J A;  3ACO A;  2Z0V A;  1I49 A;  1X04 A;  4BGJ A;  3IQ2 A;  3QE6 A;  2CSK A;  1ZWW A;  1URU A;  1X03 A;  4AVM A;  5C5B A;  4HAS A;  1OCS A;  2D4C A;  2RED A;  1KQ6 A;  4BNE A;  2FIC A;  4NSW A;  1OCU A;  1I4T A;  2Q13 A;  3FOG A;  4IKB A;  4I1Q A;  2Z0O A;  2YPS A;  3SOG A;  3G9G A;  2I4K A;  3QNI A;  2X3X A;  4ON3 A;  3LLL A;  2EFL A;  4H8S A;  4DCN C;  1KMD A;  2RAJ A;  3PLT A;  2REA A;  1I4D A;  3CAZ A;  4WPC A;  2YKT A;  2RAI A;  2WWE A;  1XTN A;  3I2W A;  3HAJ A;  4PQP A;  1I4L A;  2Z0N A;  4AKV A;  4PQO A;  4WPE A;  1O7K A;  4IKD A;  4FZS A;  4OXW A;  4DYL A;  3HPC X;  2IWL X;  2X3V A;  3Q0K A;  3DYT A;  1H6H A;  2C08 A;  2V6V A;  3SYV A;  1WDZ A;  2X3W A;  3OK8 A;  2ELB A;  4ATM A;  3HPB A;  4NQI A;  2V0O A;  2D1L A;  4AZ9 A;  2ETT A;  5C5B B; 
#chains in the Genus database with same CATH topology
 4HR1 B;  2CZO A;  3P0C A;  4IKB B;  3I01 A;  2AR5 A;  1E9V A;  3D50 A;  3EJT A;  4E3C A;  3RV1 A;  3QWE A;  4EZS A;  3B52 X;  3LUI A;  1DKX A;  2ND0 A;  3HAI A;  3HAH A;  3M3W A;  4P2J A;  3RPM A;  1U00 A;  3DDF A;  4R5K A;  1SU6 A;  4EZY A;  2CSK A;  1URU A;  3D52 A;  4HAS A;  1OCU A;  4JLC A;  3FOG A;  4IKB A;  1O7D B;  4I1Q A;  2PMR A;  2QKW A;  3T46 A;  3G9G A;  4ON3 A;  4B9Q A;  4H8S A;  1KMD A;  2OBL A;  2REA A;  2YKT A;  3I39 X;  2OBM A;  2EX3 B;  3DX2 A;  4PQP A;  3ERC C;  1TQU A;  4IM2 A;  4M0M A;  2Z0N A;  4EZR A;  4PQO A;  4AZI A;  4IKD A;  4R5I A;  3BUD A;  2GAF D;  4R5L A;  1PS3 A;  3QA8 A;  2ND1 A;  3VEA A;  3D4Z A;  1H6H A;  2O0I 1;  1WDZ A;  3OWG A;  3DX1 A;  3OK8 A;  2X5C A;  4EZP A;  2YIB A;  3HPB A;  3DDG A;  2YIV X;  3DX4 A;  4AZ9 A;  3BUB A;  1GNL A;  4EZT A;  3D4Y A;  2YLA A;  2Q12 A;  2EFK A;  2GA9 D;  4JWI A;  2NCZ A;  1OAO A;  1HWW A;  3L3P A;  2L73 A;  1Y2O A;  3QNJ A;  1O7D C;  1LQ7 A;  2DYB A;  5KBP A;  2QFF A;  1GNT A;  2YL6 A;  4IWQ A;  1SU8 A;  3CZN A;  3C7N A;  4EZU A;  2Z0V A;  4JNF A;  1R5E A;  4R5G A;  4NPH A;  2Z8Y A;  1ZWW A;  3BVU A;  3DX0 A;  1OCS A;  2RED A;  1R34 A;  4NSW A;  3LMF A;  3B51 X;  2Z0O A;  3O3O B;  4JN4 A;  2I4K A;  2X3X A;  3CV5 A;  3PLT A;  2F7O A;  4AZC A;  3BUI A;  2RAI A;  2WWE A;  1XTN A;  3I2W A;  4R5J A;  3T49 A;  4EZN A;  3EJQ A;  2JNS A;  1I4L A;  3KAW A;  4HR1 A;  2YLL A;  4EZX A;  2RT6 A;  4JWD A;  3ER8 C;  4KIK B;  5FIG A;  4FZS A;  4OXW A;  3FD9 A;  4AZ7 A;  2IWL X;  3DPQ A;  3CKD A;  3A98 A;  1TQV A;  2WYH A;  4EZW A;  2X3W A;  3BVX A;  2OW7 A;  2F7R A;  3RV0 A;  2V0O A;  3BUQ A;  4H6I A;  4AZ5 A;  5C5B B;  4HY9 A;  3LVT A;  3GI7 A;  4P2I A;  1GD5 A;  1W9M A;  4JNE A;  1SU7 A;  4KIK A;  3KAV A;  3B53 X;  1ZYL A;  3Q84 A;  3EJS A;  4JL9 A;  5FLE X;  4H6H A;  1I49 A;  1X04 A;  3O3N B;  3IQ2 A;  2PY6 A;  2YIA A;  3D2E A;  5C5B A;  4IW0 A;  2YL5 A;  2D4C A;  1KQ6 A;  4BNE A;  1I4T A;  2Q13 A;  2GF4 A;  2OO2 A;  4F00 A;  2WIN M;  4UDY X;  4DCN C;  4AZB A;  3CAZ A;  3DX3 A;  3I04 A;  4EZV A;  3HAJ A;  3F7W A;  1MJG A;  2LXY A;  4JWC A;  3ZED A;  2F1A A;  4AKV A;  2LM0 A;  2ALW A;  3CZS A;  4WPE A;  3DPO A;  3HPC X;  3D51 A;  3VEB A;  1JQK A;  1TQT A;  2C08 A;  2V6V A;  3T48 A;  2MI7 A;  3KDR A;  1E2U A;  4IWP A;  3D2F A;  2YI8 A;  2JNK A;  4ATM A;  1E1D A;  4NQI A;  3L3O M;  2D1L A;  4FM3 A;  4AZH A;  2ETT A;  3EJP A;  4UDX X;  1R33 A;  3DPP A;  2OZN B;  1DKZ A;  2V14 A;  3CVR A;  3ER9 B;  3BUP A;  2RAK A;  1XTE A;  4PZG A;  3ABH A;  2F18 A;  4HYB A;  1SUF A;  2YI9 A;  1TQW A;  3VKH A;  4EZO A;  4EZQ A;  3ACO A;  5TKY A;  4PO2 A;  4BGJ A;  3QE6 A;  3T47 A;  2N3K A;  1X03 A;  4AVM A;  1OA0 A;  4FZP A;  4FZO A;  3UIT A;  2WYI A;  4IM0 A;  2FIC A;  1DKY A;  2KHO A;  2F7P A;  4AZG A;  2F7Q A;  2YPS A;  4IM3 A;  3SOG A;  4F01 A;  1QWU A;  3QNI A;  3LLL A;  2EFL A;  4JWE A;  4AZ6 A;  3T4A G;  2RAJ A;  3O3M B;  1TQS A;  1HXK A;  1I4D A;  4WPC A;  3BLB A;  4G6Q A;  1HTY A;  4EZZ A;  2QXL A;  5E84 A;  2OW6 A;  4E81 A;  3OHX M;  2YL9 A;  2ZXQ A;  4D8J A;  3BVW A;  1UPX A;  3BVT A;  1YWM A;  1QX1 A;  2EWF A;  1O7K A;  3BVV A;  2F1B A;  1QWN A;  4DYL A;  2X3V A;  3Q0K A;  3DYT A;  3EJR A;  3EJU A;  3SYV A;  4AZC B;  2ELB A;  2FYV A;  1OA1 A;  1GN9 A;  2YL8 A;  4IWO A; 
#chains in the Genus database with same CATH homology
 2CZO A;  4P2I A;  3P0C A;  1GD5 A;  4IKB B;  2Q12 A;  2AR5 A;  2EFK A;  2V14 A;  2L73 A;  1Y2O A;  3QWE A;  2RAK A;  2DYB A;  3LUI A;  1XTE A;  3Q84 A;  4PZG A;  3ABH A;  3HAI A;  3HAH A;  3M3W A;  4P2J A;  3ACO A;  2Z0V A;  1I49 A;  1X04 A;  4BGJ A;  3IQ2 A;  3QE6 A;  2CSK A;  1ZWW A;  1URU A;  1X03 A;  4AVM A;  5C5B A;  4HAS A;  1OCS A;  2D4C A;  2RED A;  1KQ6 A;  4BNE A;  2FIC A;  4NSW A;  1OCU A;  1I4T A;  2Q13 A;  3FOG A;  4IKB A;  4I1Q A;  2Z0O A;  2YPS A;  3SOG A;  3G9G A;  2I4K A;  3QNI A;  2X3X A;  4ON3 A;  3LLL A;  2EFL A;  4H8S A;  4DCN C;  1KMD A;  2RAJ A;  3PLT A;  2REA A;  1I4D A;  3CAZ A;  4WPC A;  2YKT A;  2RAI A;  2WWE A;  1XTN A;  3I2W A;  3HAJ A;  4PQP A;  1I4L A;  2Z0N A;  4AKV A;  4PQO A;  4WPE A;  1O7K A;  4IKD A;  4FZS A;  4OXW A;  4DYL A;  3HPC X;  2IWL X;  2X3V A;  3Q0K A;  3DYT A;  1H6H A;  2C08 A;  2V6V A;  3SYV A;  1WDZ A;  2X3W A;  3OK8 A;  2ELB A;  4ATM A;  3HPB A;  4NQI A;  2V0O A;  2D1L A;  4AZ9 A;  2ETT A;  5C5B B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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