4AKVA

Crystal structure of human sorting nexin 33 (snx33)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
363
structure length
345
Chain Sequence
MYSIEMGPRGPQWKANPHPFACSVEDPISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Human Sorting Nexin 33
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SORTING NEXIN-33
total genus 140
structure length 345
sequence length 363
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4akvA02
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4akvA01
2ETTA 2DYBA 2Q12A 1XTNA 2WWEA 1Y2OA 2CSKA 3QWEA 2D4CA 4H8SA 1OCUA 3HAHA 4DYLA 3HPBA 4AVMA 3ABHA 2YPSA 4FZSA 2V14A 1XTEA 3ACOA 4DCNC 3CAZA 3DYTA 1I4DA 2RAIA 4ATMA 4IKBA 3Q84A 2REAA 1O7KA 2I4KA 4IKDA 5C5BB 3OK8A 3LUIA 4BGJA 2L73A 4P2IA 1URUA 2CZOA 4AKVA 4I1QA 1OCSA 2V6VA 2RAKA 2FICA 3QNIA 2ELBA 3LLLA 3I2WA 3G9GA 4AZ9A 2Z0VA 4HASA 1I4LA 2EFLA 1KMDA 1I49A 1X04A 4PQOA 3SYVA 3P0CA 3Q0KA 5C5BA 3QE6A 2AR5A 3HPCX 2RAJA 4WPCA 3SOGA 1ZWWA 1H6HA 3FOGA 1X03A 1I4TA 4NSWA 4PZGA 2X3VA 4P2JA 2V0OA 4PQPA 4IKBB 3PLTA 4OXWA 1WDZA 4BNEA 2Z0NA 2IWLX 2C08A 2X3WA 4NQIA 1KQ6A 1GD5A 3HAIA 2X3XA 4ON3A 2D1LA 3M3WA 2Z0OA 3HAJA 2Q13A 2EFKA 3IQ2A 4WPEA 2REDA 2YKTA
chains in the Genus database with same CATH superfamily
5FIGA 1SU7A 3I39X 4F01A 2ETTA 2Q12A 1XTNA 3D4YA 3EJTA 1Y2OA 3ER8C 4IM0A 4EZYA 3HPBA 3D4ZA 4EZWA 3DPPA 3B52X 4H6IA 2V14A 4EZNA 2ZXQA 3D50A 3DYTA 4FZOA 4NPHA 4IKDA 1OAOA 2O0I1 3DPQA 2CZOA 4KIKA 4HR1B 4I1QA 2YL6A 4JNEA 2YL9A 3T4AG 1OA1A 4JWDA 3LLLA 1E2UA 2Z0VA 3RV0A 4EZPA 1I4LA 4PQOA 3SYVA 2YIVX 2F7QA 3D51A 3HPCX 2RAJA 3KAWA 3SOGA 3BUQA 4HY9A 3FOGA 4R5IA 3VEAA 2QXLA 2OW7A 1HXKA 3BUIA 1TQUA 3PLTA 4H6HA 4BNEA 3BVXA 2WYIA 4JWCA 4R5KA 2X3WA 4NQIA 3CZNA 5TKYA 1HWWA 3B51X 2X5CA 3EJUA 4EZZA 3FD9A 2X3XA 1JQKA 1R33A 1TQVA 4EZRA 2F1AA 2Z0OA 3HAJA 2EFKA 3CV5A 3IQ2A 3DPOA 2REDA 2MI7A 2QFFA 4IM2A 4AZ5A 2WWEA 3ZEDA 2GA9D 2YL8A 3CKDA 3QWEA 4AZCA 3HAHA 4R5LA 3BUPA 4AVMA 4JNFA 4G6QA 3C7NA 2YPSA 3L3OM 1U00A 2RAIA 4FZPA 3KDRA 4IWOA 3CZSA 2OBLA 2REAA 4JWIA 1O7KA 2YIAA 3OHXM 2I4KA 1YWMA 3LUIA 1TQWA 4UDYX 3DX1A 4AKVA 3ERCC 2F1BA 4AZ7A 1DKZA 4D8JA 4JLCA 2PMRA 4UDXX 3I2WA 3G9GA 4AZ9A 2ND1A 4HASA 1DKXA 5FLEX 1X04A 3P0CA 3Q0KA 5C5BA 2AR5A 2F7OA 1TQSA 1H6HA 4IWPA 1I4TA 4P2JA 2V0OA 2OBMA 1E9VA 4R5GA 2Z0NA 2C08A 4AZCB 2YLAA 1QWNA 4M0MA 4AZ6A 2RT6A 2OW6A 3M3WA 4WPEA 1SUFA 3VEBA 4FM3A 2DYBA 1DKYA 4E81A 4AZGA 2CSKA 1OCUA 2YI8A 3VKHA 4EZVA 3ABHA 4FZSA 2YI9A 3DDGA 1I4DA 1UPXA 3O3NB 3DX4A 4E3CA 2KHOA 2Z8YA 3LVTA 3UITA 5C5BB 3OK8A 4BGJA 1TQTA 1URUA 1GNTA 4EZSA 1OCSA 2V6VA 2FICA 2F18A 3L3PA 3T47A 4AZHA 4EZXA 1SU6A 3QE6A 4IM3A 1GNLA 4WPCA 1ZWWA 3D52A 1X03A 3DX2A 4PZGA 2NCZA 3QNJA 2LM0A 3O3OB 2X3VA 3KAVA 4HYBA 4PQPA 4IKBB 2EX3B 2PY6A 3OWGA 1PS3A 1WDZA 2YLLA 2YIBA 3EJPA 2GF4A 1GD5A 3HAIA 3DX3A 4ON3A 3RV1A 2Q13A 3T49A 4F00A 3CVRA 1O7DB 4IW0A 2D4CA 4H8SA 4DYLA 1XTEA 3ACOA 3I04A 2JNKA 4DCNC 2EWFA 3CAZA 1QX1A 3BLBA 3EJQA 4PO2A 4ATMA 2YL5A 4IKBA 3BUDA 3Q84A 4B9QA 3F7WA 1R5EA 2OO2A 1MJGA 2L73A 4P2IA 4EZOA 4JL9A 2WYHA 3BVTA 5KBPA 2QKWA 4R5JA 1SU8A 1W9MA 2RAKA 3A98A 3GI7A 3QNIA 3T46A 2ELBA 3RPMA 2OZNB 3D2FA 2JNSA 2ALWA 1ZYLA 2F7RA 3BVVA 2EFLA 3BUBA 3BVWA 1KMDA 1I49A 1HTYA 3DX0A 3D2EA 2FYVA 2N3KA 3EJSA 3EJRA 4EZUA 4HR1A 5E84A 1O7DC 3LMFA 1E1DA 4NSWA 2F7PA 4AZBA 4IWQA 4JN4A 4EZQA 4EZTA 4OXWA 3DDFA 1OA0A 1GN9A 1LQ7A 3I01A 2WINM 2IWLX 3O3MB 2LXYA 1QWUA 2GAFD 1KQ6A 4KIKB 3B53X 3ER9B 3T48A 4JWEA 3BVUA 2D1LA 3QA8A 4AZIA 1R34A 2ND0A 2YKTA
chains in the Genus database with same CATH topology
2ETTA 2DYBA 2Q12A 1XTNA 2WWEA 1Y2OA 2CSKA 3QWEA 2D4CA 4H8SA 1OCUA 3HAHA 4DYLA 3HPBA 4AVMA 3ABHA 2YPSA 4FZSA 2V14A 1XTEA 3ACOA 4DCNC 3CAZA 3DYTA 1I4DA 2RAIA 4ATMA 4IKBA 3Q84A 2REAA 1O7KA 2I4KA 4IKDA 5C5BB 3OK8A 3LUIA 4BGJA 2L73A 4P2IA 1URUA 2CZOA 4AKVA 4I1QA 1OCSA 2V6VA 2RAKA 2FICA 3QNIA 2ELBA 3LLLA 3I2WA 3G9GA 4AZ9A 2Z0VA 4HASA 1I4LA 2EFLA 1KMDA 1I49A 1X04A 4PQOA 3SYVA 3P0CA 3Q0KA 5C5BA 3QE6A 2AR5A 3HPCX 2RAJA 4WPCA 3SOGA 1ZWWA 1H6HA 3FOGA 1X03A 1I4TA 4NSWA 4PZGA 2X3VA 4P2JA 2V0OA 4PQPA 4IKBB 3PLTA 4OXWA 1WDZA 4BNEA 2Z0NA 2IWLX 2C08A 2X3WA 4NQIA 1KQ6A 1GD5A 3HAIA 2X3XA 4ON3A 2D1LA 3M3WA 2Z0OA 3HAJA 2Q13A 2EFKA 3IQ2A 4WPEA 2REDA 2YKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ETT A;  2DYB A;  2Q12 A;  1XTN A;  2WWE A;  1Y2O A;  2CSK A;  3QWE A;  2D4C A;  4H8S A;  1OCU A;  3HAH A;  4DYL A;  3HPB A;  4AVM A;  3ABH A;  2YPS A;  4FZS A;  2V14 A;  1XTE A;  3ACO A;  4DCN C;  3CAZ A;  3DYT A;  1I4D A;  2RAI A;  4ATM A;  4IKB A;  3Q84 A;  2REA A;  1O7K A;  2I4K A;  4IKD A;  5C5B B;  3OK8 A;  3LUI A;  4BGJ A;  2L73 A;  4P2I A;  1URU A;  2CZO A;  4AKV A;  4I1Q A;  1OCS A;  2V6V A;  2RAK A;  2FIC A;  3QNI A;  2ELB A;  3LLL A;  3I2W A;  3G9G A;  4AZ9 A;  2Z0V A;  4HAS A;  1I4L A;  2EFL A;  1KMD A;  1I49 A;  1X04 A;  4PQO A;  3SYV A;  3P0C A;  3Q0K A;  5C5B A;  3QE6 A;  2AR5 A;  3HPC X;  2RAJ A;  4WPC A;  3SOG A;  1ZWW A;  1H6H A;  3FOG A;  1X03 A;  1I4T A;  4NSW A;  4PZG A;  2X3V A;  4P2J A;  2V0O A;  4PQP A;  4IKB B;  3PLT A;  4OXW A;  1WDZ A;  4BNE A;  2Z0N A;  2IWL X;  2C08 A;  2X3W A;  4NQI A;  1KQ6 A;  1GD5 A;  3HAI A;  2X3X A;  4ON3 A;  2D1L A;  3M3W A;  2Z0O A;  3HAJ A;  2Q13 A;  2EFK A;  3IQ2 A;  4WPE A;  2RED A;  2YKT A; 
#chains in the Genus database with same CATH topology
 5FIG A;  1SU7 A;  3I39 X;  4F01 A;  2ETT A;  2Q12 A;  1XTN A;  3D4Y A;  3EJT A;  1Y2O A;  3ER8 C;  4IM0 A;  4EZY A;  3HPB A;  3D4Z A;  4EZW A;  3DPP A;  3B52 X;  4H6I A;  2V14 A;  4EZN A;  2ZXQ A;  3D50 A;  3DYT A;  4FZO A;  4NPH A;  4IKD A;  1OAO A;  2O0I 1;  3DPQ A;  2CZO A;  4KIK A;  4HR1 B;  4I1Q A;  2YL6 A;  4JNE A;  2YL9 A;  3T4A G;  1OA1 A;  4JWD A;  3LLL A;  1E2U A;  2Z0V A;  3RV0 A;  4EZP A;  1I4L A;  4PQO A;  3SYV A;  2YIV X;  2F7Q A;  3D51 A;  3HPC X;  2RAJ A;  3KAW A;  3SOG A;  3BUQ A;  4HY9 A;  3FOG A;  4R5I A;  3VEA A;  2QXL A;  2OW7 A;  1HXK A;  3BUI A;  1TQU A;  3PLT A;  4H6H A;  4BNE A;  3BVX A;  2WYI A;  4JWC A;  4R5K A;  2X3W A;  4NQI A;  3CZN A;  5TKY A;  1HWW A;  3B51 X;  2X5C A;  3EJU A;  4EZZ A;  3FD9 A;  2X3X A;  1JQK A;  1R33 A;  1TQV A;  4EZR A;  2F1A A;  2Z0O A;  3HAJ A;  2EFK A;  3CV5 A;  3IQ2 A;  3DPO A;  2RED A;  2MI7 A;  2QFF A;  4IM2 A;  4AZ5 A;  2WWE A;  3ZED A;  2GA9 D;  2YL8 A;  3CKD A;  3QWE A;  4AZC A;  3HAH A;  4R5L A;  3BUP A;  4AVM A;  4JNF A;  4G6Q A;  3C7N A;  2YPS A;  3L3O M;  1U00 A;  2RAI A;  4FZP A;  3KDR A;  4IWO A;  3CZS A;  2OBL A;  2REA A;  4JWI A;  1O7K A;  2YIA A;  3OHX M;  2I4K A;  1YWM A;  3LUI A;  1TQW A;  4UDY X;  3DX1 A;  4AKV A;  3ERC C;  2F1B A;  4AZ7 A;  1DKZ A;  4D8J A;  4JLC A;  2PMR A;  4UDX X;  3I2W A;  3G9G A;  4AZ9 A;  2ND1 A;  4HAS A;  1DKX A;  5FLE X;  1X04 A;  3P0C A;  3Q0K A;  5C5B A;  2AR5 A;  2F7O A;  1TQS A;  1H6H A;  4IWP A;  1I4T A;  4P2J A;  2V0O A;  2OBM A;  1E9V A;  4R5G A;  2Z0N A;  2C08 A;  4AZC B;  2YLA A;  1QWN A;  4M0M A;  4AZ6 A;  2RT6 A;  2OW6 A;  3M3W A;  4WPE A;  1SUF A;  3VEB A;  4FM3 A;  2DYB A;  1DKY A;  4E81 A;  4AZG A;  2CSK A;  1OCU A;  2YI8 A;  3VKH A;  4EZV A;  3ABH A;  4FZS A;  2YI9 A;  3DDG A;  1I4D A;  1UPX A;  3O3N B;  3DX4 A;  4E3C A;  2KHO A;  2Z8Y A;  3LVT A;  3UIT A;  5C5B B;  3OK8 A;  4BGJ A;  1TQT A;  1URU A;  1GNT A;  4EZS A;  1OCS A;  2V6V A;  2FIC A;  2F18 A;  3L3P A;  3T47 A;  4AZH A;  4EZX A;  1SU6 A;  3QE6 A;  4IM3 A;  1GNL A;  4WPC A;  1ZWW A;  3D52 A;  1X03 A;  3DX2 A;  4PZG A;  2NCZ A;  3QNJ A;  2LM0 A;  3O3O B;  2X3V A;  3KAV A;  4HYB A;  4PQP A;  4IKB B;  2EX3 B;  2PY6 A;  3OWG A;  1PS3 A;  1WDZ A;  2YLL A;  2YIB A;  3EJP A;  2GF4 A;  1GD5 A;  3HAI A;  3DX3 A;  4ON3 A;  3RV1 A;  2Q13 A;  3T49 A;  4F00 A;  3CVR A;  1O7D B;  4IW0 A;  2D4C A;  4H8S A;  4DYL A;  1XTE A;  3ACO A;  3I04 A;  2JNK A;  4DCN C;  2EWF A;  3CAZ A;  1QX1 A;  3BLB A;  3EJQ A;  4PO2 A;  4ATM A;  2YL5 A;  4IKB A;  3BUD A;  3Q84 A;  4B9Q A;  3F7W A;  1R5E A;  2OO2 A;  1MJG A;  2L73 A;  4P2I A;  4EZO A;  4JL9 A;  2WYH A;  3BVT A;  5KBP A;  2QKW A;  4R5J A;  1SU8 A;  1W9M A;  2RAK A;  3A98 A;  3GI7 A;  3QNI A;  3T46 A;  2ELB A;  3RPM A;  2OZN B;  3D2F A;  2JNS A;  2ALW A;  1ZYL A;  2F7R A;  3BVV A;  2EFL A;  3BUB A;  3BVW A;  1KMD A;  1I49 A;  1HTY A;  3DX0 A;  3D2E A;  2FYV A;  2N3K A;  3EJS A;  3EJR A;  4EZU A;  4HR1 A;  5E84 A;  1O7D C;  3LMF A;  1E1D A;  4NSW A;  2F7P A;  4AZB A;  4IWQ A;  4JN4 A;  4EZQ A;  4EZT A;  4OXW A;  3DDF A;  1OA0 A;  1GN9 A;  1LQ7 A;  3I01 A;  2WIN M;  2IWL X;  3O3M B;  2LXY A;  1QWU A;  2GAF D;  1KQ6 A;  4KIK B;  3B53 X;  3ER9 B;  3T48 A;  4JWE A;  3BVU A;  2D1L A;  3QA8 A;  4AZI A;  1R34 A;  2ND0 A;  2YKT A; 
#chains in the Genus database with same CATH homology
 2ETT A;  2DYB A;  2Q12 A;  1XTN A;  2WWE A;  1Y2O A;  2CSK A;  3QWE A;  2D4C A;  4H8S A;  1OCU A;  3HAH A;  4DYL A;  3HPB A;  4AVM A;  3ABH A;  2YPS A;  4FZS A;  2V14 A;  1XTE A;  3ACO A;  4DCN C;  3CAZ A;  3DYT A;  1I4D A;  2RAI A;  4ATM A;  4IKB A;  3Q84 A;  2REA A;  1O7K A;  2I4K A;  4IKD A;  5C5B B;  3OK8 A;  3LUI A;  4BGJ A;  2L73 A;  4P2I A;  1URU A;  2CZO A;  4AKV A;  4I1Q A;  1OCS A;  2V6V A;  2RAK A;  2FIC A;  3QNI A;  2ELB A;  3LLL A;  3I2W A;  3G9G A;  4AZ9 A;  2Z0V A;  4HAS A;  1I4L A;  2EFL A;  1KMD A;  1I49 A;  1X04 A;  4PQO A;  3SYV A;  3P0C A;  3Q0K A;  5C5B A;  3QE6 A;  2AR5 A;  3HPC X;  2RAJ A;  4WPC A;  3SOG A;  1ZWW A;  1H6H A;  3FOG A;  1X03 A;  1I4T A;  4NSW A;  4PZG A;  2X3V A;  4P2J A;  2V0O A;  4PQP A;  4IKB B;  3PLT A;  4OXW A;  1WDZ A;  4BNE A;  2Z0N A;  2IWL X;  2C08 A;  2X3W A;  4NQI A;  1KQ6 A;  1GD5 A;  3HAI A;  2X3X A;  4ON3 A;  2D1L A;  3M3W A;  2Z0O A;  3HAJ A;  2Q13 A;  2EFK A;  3IQ2 A;  4WPE A;  2RED A;  2YKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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