3ZM5A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
molecule tags Ligase
source organism Streptococcus pneumoniae r6
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
total genus 143
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm5A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm5A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm5A03
3N2AA 2Y1OA 3LK7A 2Y67A 2X5OA 1W78A 2UUPA 2VTDA 4BUBA 3UAGA 1GG4A 2UAGA 1FGSA 1J6UA 2WTZA 3MVNA 2WJPA 1UAGA 4ZIYA 4C12A 2AM1A 2GCAA 2XJAA 4IHHA 4UAGA 1JBVA 1JBWA 2VTEA 3NRSA 4CVMA 2VORA 3ZM5A 2IU9A 2Y66A 1EEHA 2IUAA 1W7KA 3PMOA 3PYZA 3EH0A 1E0DA 2JFHA 4CVLA 2XPCA 2F00A 2GC6A 3QCZA 4CVKA 3ZM6A 4IHGA 3HN7A 2AM2A 2GCBA 4E79A 1P3DA 5A5EA 2Y68A 1E8CA 2UUOA 2VOSA 3ZL8A 4IHFA 2JFGA 4BUCA 1O5ZA 4HV4A 5A5FA 1P31A 2JFFA 3EAGA 1GQYA 4QDIA 4QF5A 2IU8A 2GC5A 4C13A 1GQQA 4E75A
chains in the Genus database with same CATH superfamily
4R30A 3IH0A 3N2AA 3L2BA 2F6TA 3RQ2A 5KA0A 4NX8A 4E69A 2CNEA 2OUDA 1U24A 4WTYA 1ONZA 1W78A 5K9VA 1M3GA 5KADA 1RFTA 2UUPA 4QUNA 2DDWA 1GG4A 3RQXA 3QCIA 3LKIA 4RI5A 1J4XA 1L8GA 2VEYA 1OEVA 4R0TA 1PH0A 1TZ6A 2WTZA 1OESA 1UAGA 3UMOA 1XXPA 2IMGA 3B1OA 3EB1A 1YWFA 4ZIYA 3RSGA 4C12A 1NWEA 3RTGA 2AM1A 3QCEA 2F6WA 3NMEA 2XJAA 4Y2EA 3RTBA 1BZCA 4DGXA 1JBVA 4NWGA 4S0GA 1JBWA 1JLNA 4K9IA 1XXVA 2PKMA 5MMZB 1QZ0A 2GWOA 3V0JA 3ZMPA 1OHDA 1V3AA 2HVLA 3QCFA 2JGVA 1G1FA 1L8KA 3BM8A 2B4UA 3H74A 2VORA 4CVMA 1I9SA 4ERCA 4ZN5A 2J16A 3V0GA 4HRFA 1EEHA 2IUAA 5HDEA 4S1IA 4E8ZA 3RRBA 2AHSA 3QCMA 2M3VA 1EENA 2SHPA 2H04A 1NNYA 5C3ZA 3QCKA 4XCKA 2QCTA 4J51A 2JFHA 1ZZWA 3NBWA 3AWEA 1OEOX 4Z6BA 3N1CA 1YPTA 4QBEA 5TRWA 2F00A 4C5JA 1PA9A 1LARA 4JBCA 3V0FA 1RFUA 4CVKA 2PSZA 2FJMA 2I6AA 3GXHA 2F7KA 3ZM6A 1Q6SA 4KAHA 3FHYA 1UA4A 3MOWA 1NL9A 2PBNA 3KTNA 3RY7A 2I42A 2VEWA 1D5RA 2V78A 3IQ0A 2Y96A 1P3DA 1ZC0A 3MOZA 3ZM1A 5KABA 2CJZA 5BZXA 2UUOA 2HC1A 3ZL8A 2B4SA 4NNDA 3WSEA 1Q6PA 4D3PA 3CQDA 2OOQA 4RI4A 3BLTA 4C5KA 4HV4A 1XRIA 1PXHA 3ZM3A 1PTYA 5EYNA 3UMPA 4EN4A 2B3OA 4PYHA 2I4HA 3D42A 1A5YA 1G7GA 1P31A 3RRFA 1ONYA 3EAGA 3O4UA 3I36A 1DGMA 4QUMA 4JJPA 1YTSA 4C5LA 1AAXA 3S3HA 4XDAA 1I9TA 5K25A 1KYHA 1RKAA 3RQHA 2HNPA 3UQ9A 4E75A 1T4JA 4K8PA 4E84A 4DGPA 3K9EA 2C4EA 5BZZA 3PS5A 4YL5A 3UBOA 4HJQA 5F0ZA 2F6VA 4BUBA 2DXPA 1R6HA 2F46A 4R0SA 5BYDA 3AWFA 2R3BA 1BZHA 2OC3A 4K8TA 5LXQB 1J6UA 1JXIA 1ECVA 1U25A 3QCCA 3V0HA 2PKKA 3RU2A 1PTTA 3KZHA 2A9ZA 2AA0A 4JNBA 3KD6A 4LBGA 1JF7A 3RPZA 4C5MA 5CGAA 4UBEA 4Y14A 1LYVA 1KAKA 2AJRA 3PL2A 3VAQA 1VM7A 2I6BA 4KBEA 2ZN7A 3RSSA 1LIKA 3VASA 1WYEA 4JKSA 3AWGA 3BGKA 3PZSA 3NRSA 4N08A 2HNQA 2AX3A 2H4GA 2Y66A 2FV7A 2NLKA 3PMOA 1EEOA 2BV5A 3RO4A 5BYEA 2HB1A 2Q05A 2CMAA 2QDPA 3BRHA 4WU2A 5F11A 2CM2A 1G4US 2Y2FA 3F9BA 2CFVA 4KADA 3OMHA 3B1RA 2JG5A 2YYBA 3NM3A 4CVLA 2XPCA 5C3YA 2NV5A 2NT2A 1LIOA 1TD2A 4OHLA 1YTWA 3QCBA 2F02A 5C40A 3IN1A 3QCDA 4K9CA 4GFUA 5KA1A 1LIJA 2VARA 4JMKA 4XF7A 2DCNA 3RU3A 4BJOA 5B6AA 2GC6A 2E0TA 5BYCA 2CMCA 2P6XA 3D1OA 3HN7A 3GO6A 2GCBA 3IE7A 2WGPA 2JG1A 4KANA 2B49A 3QCLA 4LBXA 1I57A 3QKPA 3B7OA 3RT9A 5A5EA 4YAAA 3ZM0A 3DZVA 1V1AA 4WJMA 3ZS7A 2B4PA 3QCJA 2VEVA 3D44A 1PTUA 4O1LA 3LJ8A 3RREA 2JFGA 2A8BA 4E8YA 5GTJA 1ESQA 5IBSA 2I6IA 3F41A 4QBWA 4WU3A 5K22A 3V0IA 2QHPA 2I6PA 5EHPA 4GFVA 3H49A 3WSHA 2JFFA 3WSDA 2FJNA 4IWGA 4EOHA 2HC2A 3BLUA 3JULA 4QDIA 2G59A 3RT7A 4OHHA 3QCNA 2BIJA 2QEPA 3MBHA 2I4EA 2NWHA 3U96A 1TYYA 4N09A 1Q6TA 2A3KA 3LK7A 3EEQA 1OHCA 2X5OA 2B4OA 4GRYA 1G4WR 1YN9A 3O3LA 2HCMA 3O4SA 3LOOA 4RDDA 2GJTA 1GC5A 4GS0A 2QBQA 4RHGA 3KEUA 1FGSA 2I6MA 3BF5A 2P4DA 5AWXA 3RQ8A 4OHIA 2AZRA 1XM2A 4KYRA 3F81A 1T48A 1T49A 3WSGA 2YDUA 3RTCA 1Q6MA 2R0BA 1RKDA 5EHRA 1XBOA 1V1SA 3RO1A 5EY7A 1NMPA 2C7SA 2H4VA 2I6JA 3I3YA 3D1HA 3NC9A 3LJSA 4EBUA 2RBCA 1MKPA 2HY3A 2J16B 1YGJA 4OHEA 2QBRA 5KA9A 3UQDA 3RGQA 4IWMA 4S1IB 3O5XA 3H2XA 2PKNA 4ICZA 2RF6A 5KA4A 2HQQA 2I75A 3QAIA 4LC4A 1EKQA 1W7KA 1YGRA 5KA7A 1ZCLA 4XF6A 1JXHA 4H34A 1Q1MA 4GE6A 4YWRA 4C5NA 1G7FA 4WOHA 1NZ7A 1BZJA 4S1MA 3RZ2A 2H02A 3EH0A 2QCVA 1L2LA 3HPDA 2BZLA 1FPZA 2I5XA 3CWEA 2F70A 3RTEA 1KAVA 4O1GA 2PQ5A 3V0EA 1UB0A 3GBUA 2QDCA 1KNXA 1WRMA 2PA5A 4GE2A 1FPRA 3D9CA 1OEMX 4QAHA 2CNHA 3QCZA 4B04A 2XTBA 4NYHA 1V19A 1NO6A 4IHGA 5M43A 3I7ZA 1YTNA 3GXGA 1C83A 2F6ZA 2GP0A 2IOJA 3NL2A 3QKQA 3D1QA 1Q6NA 3DRWA 1RK2A 4E79A 1X24A 2VEUA 3S3FA 1RXDA 3EU0A 3UQEA 2VEXA 2DDOA 4MBBA 1E8CA 4DU5A 3WSFA 3NM1A 2NZ6A 4IHFA 1YZ4A 4K8KA 4BUCA 4GWFA 2AJPA 3RPHA 4D3RA 1U2XA 5CM5A 5COJA 1PYNA 4E8WA 2CMBA 1YHJA 1VI9A 3NL5A 1ESJA 3OTXA 4K8CA 2F71A 3RTDA 3RGOA 2PT0A 5KA8A 1VK4A 4GM6A 3RSQA 5TQIA 4GE5A 3NBVA 1NMOA 2F6YA 2J17A 3RQQA 2JJDA 5BUGA 4QF5A 2IU8A 1LQFA 4C13A 1VHRA 4JMJA 2ABQA 4RH9A 3GO7A 3EMUA 4DC3A 3NCAA 2Y1OA 5KACA 1PTVA 2BGEA 3B1QA 1LHPA 2Y67A 4KI9A 1RPMA 2CNIA 3IBQA 2CM7A 4AZ1A 4D3QA 5J8RA 1G1HA 1BX4A 2QBPA 3QCHA 1YGKA 2VTDA 2I5BA 2AB8A 3UAGA 4B8SA 3LHXA 5K24A 2UAGA 1LHRA 5KAAA 1LIIA 3UQ6A 2A9YA 2OZ5A 3HICA 3CM3A 2WJPA 3MVNA 2H4KA 2HLZA 1C84A 1C3QA 3MMJA 5IBMA 2I3RA 3K5WA 3SR9A 3ZMQA 4H1OA 2GCAA 3B3LA 3RRJA 3RS8A 1OETA 4EUMA 5BYFA 2AWDA 2B07A 3S3KA 3S4OA 1NWLA 4UAGA 4IHHA 3V0DA 2VTEA 3EWMA 2R3EA 3ZM2A 1C87A 4JKUA 2ABSA 1WAXA 1C88A 1V1BA 4U7XA 1Q6JA 4RKKA 4S1HA 1OEUA 5K23A 3ZM5A 1EKKA 2IU9A 3IKHA 4YR8B 4BPCA 4HJPA 1G1GA 2PI7A 3F9AA 2QDMA 4IKCA 1RFVA 2FH7A 1TZ3A 3PYZA 2PKFA 4I8NA 1GFYA 2MBCA 1E0DA 3A5JA 2BGDA 1QXKA 3RM5A 1GWZA 2I6OA 1YFOA 5KA2A 3ZV2A 1PA1A 2CM3A 4PVGA 4X8FA 1WCHA 5KA3A 2C46A 1RKSA 3RQ5A 2I1YA 3EZZA 4K93A 1P15A 2Q5RA 4ZI4A 2I3UA 1U26A 4GRZA 5BX1A 1C85A 1KO7A 3B1PA 2I4GA 4KYQA 3S4EA 3NL6A 4ZRTA 2YXUA 4TVVA 4RH5A 1C86A 2CM8A 2HXPA 3I80A 4PVVA 2AM2A 1GQTA 4E3AA 2ESBA 2NTAA 3M4UA 3L31A 2AFBA 3QA2A 2Q47A 5I6VA 3WSIA 1FQ1A 3B1NA 3EAXA 2Y68A 4OHDA 2QBSA 2DDMA 3O4TA 2VOSA 4KALA 2FYWA 3W4SA 2NT7A 2QCJA 3RS9A 1O5ZA 3HJ6A 3HYOA 1OHEA 2HW1A 5A5FA 2ZMMA 3Q92A 3NC2A 3S3EA 4B8RA 3RSFA 3QCGA 3Q1YA 3RTAA 1ZCKA 4QAPA 3SMEA 3FHXA 2CNGA 3F99A 5CGEA 2C49A 1YGUA 2CNFA 3N0AA 3OLRA 1SUGA 4LCAA 3NL3A 2F6FA 2G6ZA 3MBJA 5K9WA 1GQYA 3A5KA 3RQ6A 4NWFA 2YXTA 2GC5A 1GQQA 2H03A 5C41A
chains in the Genus database with same CATH topology
3N2AA 2Y1OA 3LK7A 2Y67A 2X5OA 1W78A 2UUPA 2VTDA 4BUBA 3UAGA 1GG4A 2UAGA 1FGSA 1J6UA 2WTZA 3MVNA 2WJPA 1UAGA 4ZIYA 4C12A 2AM1A 2GCAA 2XJAA 4IHHA 4UAGA 1JBVA 1JBWA 2VTEA 3NRSA 4CVMA 2VORA 3ZM5A 2IU9A 2Y66A 1EEHA 2IUAA 1W7KA 3PMOA 3PYZA 3EH0A 1E0DA 2JFHA 4CVLA 2XPCA 2F00A 2GC6A 3QCZA 4CVKA 3ZM6A 4IHGA 3HN7A 2AM2A 2GCBA 4E79A 1P3DA 5A5EA 2Y68A 1E8CA 2UUOA 2VOSA 3ZL8A 4IHFA 2JFGA 4BUCA 1O5ZA 4HV4A 5A5FA 1P31A 2JFFA 3EAGA 1GQYA 4QDIA 4QF5A 2IU8A 2GC5A 4C13A 1GQQA 4E75A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N2A A;  2Y1O A;  3LK7 A;  2Y67 A;  2X5O A;  1W78 A;  2UUP A;  2VTD A;  4BUB A;  3UAG A;  1GG4 A;  2UAG A;  1FGS A;  1J6U A;  2WTZ A;  3MVN A;  2WJP A;  1UAG A;  4ZIY A;  4C12 A;  2AM1 A;  2GCA A;  2XJA A;  4IHH A;  4UAG A;  1JBV A;  1JBW A;  2VTE A;  3NRS A;  4CVM A;  2VOR A;  3ZM5 A;  2IU9 A;  2Y66 A;  1EEH A;  2IUA A;  1W7K A;  3PMO A;  3PYZ A;  3EH0 A;  1E0D A;  2JFH A;  4CVL A;  2XPC A;  2F00 A;  2GC6 A;  3QCZ A;  4CVK A;  3ZM6 A;  4IHG A;  3HN7 A;  2AM2 A;  2GCB A;  4E79 A;  1P3D A;  5A5E A;  2Y68 A;  1E8C A;  2UUO A;  2VOS A;  3ZL8 A;  4IHF A;  2JFG A;  4BUC A;  1O5Z A;  4HV4 A;  5A5F A;  1P31 A;  2JFF A;  3EAG A;  1GQY A;  4QDI A;  4QF5 A;  2IU8 A;  2GC5 A;  4C13 A;  1GQQ A;  4E75 A; 
#chains in the Genus database with same CATH topology
 4R30 A;  3IH0 A;  3N2A A;  3L2B A;  2F6T A;  3RQ2 A;  5KA0 A;  4NX8 A;  4E69 A;  2CNE A;  2OUD A;  1U24 A;  4WTY A;  1ONZ A;  1W78 A;  5K9V A;  1M3G A;  5KAD A;  1RFT A;  2UUP A;  4QUN A;  2DDW A;  1GG4 A;  3RQX A;  3QCI A;  3LKI A;  4RI5 A;  1J4X A;  1L8G A;  2VEY A;  1OEV A;  4R0T A;  1PH0 A;  1TZ6 A;  2WTZ A;  1OES A;  1UAG A;  3UMO A;  1XXP A;  2IMG A;  3B1O A;  3EB1 A;  1YWF A;  4ZIY A;  3RSG A;  4C12 A;  1NWE A;  3RTG A;  2AM1 A;  3QCE A;  2F6W A;  3NME A;  2XJA A;  4Y2E A;  3RTB A;  1BZC A;  4DGX A;  1JBV A;  4NWG A;  4S0G A;  1JBW A;  1JLN A;  4K9I A;  1XXV A;  2PKM A;  5MMZ B;  1QZ0 A;  2GWO A;  3V0J A;  3ZMP A;  1OHD A;  1V3A A;  2HVL A;  3QCF A;  2JGV A;  1G1F A;  1L8K A;  3BM8 A;  2B4U A;  3H74 A;  2VOR A;  4CVM A;  1I9S A;  4ERC A;  4ZN5 A;  2J16 A;  3V0G A;  4HRF A;  1EEH A;  2IUA A;  5HDE A;  4S1I A;  4E8Z A;  3RRB A;  2AHS A;  3QCM A;  2M3V A;  1EEN A;  2SHP A;  2H04 A;  1NNY A;  5C3Z A;  3QCK A;  4XCK A;  2QCT A;  4J51 A;  2JFH A;  1ZZW A;  3NBW A;  3AWE A;  1OEO X;  4Z6B A;  3N1C A;  1YPT A;  4QBE A;  5TRW A;  2F00 A;  4C5J A;  1PA9 A;  1LAR A;  4JBC A;  3V0F A;  1RFU A;  4CVK A;  2PSZ A;  2FJM A;  2I6A A;  3GXH A;  2F7K A;  3ZM6 A;  1Q6S A;  4KAH A;  3FHY A;  1UA4 A;  3MOW A;  1NL9 A;  2PBN A;  3KTN A;  3RY7 A;  2I42 A;  2VEW A;  1D5R A;  2V78 A;  3IQ0 A;  2Y96 A;  1P3D A;  1ZC0 A;  3MOZ A;  3ZM1 A;  5KAB A;  2CJZ A;  5BZX A;  2UUO A;  2HC1 A;  3ZL8 A;  2B4S A;  4NND A;  3WSE A;  1Q6P A;  4D3P A;  3CQD A;  2OOQ A;  4RI4 A;  3BLT A;  4C5K A;  4HV4 A;  1XRI A;  1PXH A;  3ZM3 A;  1PTY A;  5EYN A;  3UMP A;  4EN4 A;  2B3O A;  4PYH A;  2I4H A;  3D42 A;  1A5Y A;  1G7G A;  1P31 A;  3RRF A;  1ONY A;  3EAG A;  3O4U A;  3I36 A;  1DGM A;  4QUM A;  4JJP A;  1YTS A;  4C5L A;  1AAX A;  3S3H A;  4XDA A;  1I9T A;  5K25 A;  1KYH A;  1RKA A;  3RQH A;  2HNP A;  3UQ9 A;  4E75 A;  1T4J A;  4K8P A;  4E84 A;  4DGP A;  3K9E A;  2C4E A;  5BZZ A;  3PS5 A;  4YL5 A;  3UBO A;  4HJQ A;  5F0Z A;  2F6V A;  4BUB A;  2DXP A;  1R6H A;  2F46 A;  4R0S A;  5BYD A;  3AWF A;  2R3B A;  1BZH A;  2OC3 A;  4K8T A;  5LXQ B;  1J6U A;  1JXI A;  1ECV A;  1U25 A;  3QCC A;  3V0H A;  2PKK A;  3RU2 A;  1PTT A;  3KZH A;  2A9Z A;  2AA0 A;  4JNB A;  3KD6 A;  4LBG A;  1JF7 A;  3RPZ A;  4C5M A;  5CGA A;  4UBE A;  4Y14 A;  1LYV A;  1KAK A;  2AJR A;  3PL2 A;  3VAQ A;  1VM7 A;  2I6B A;  4KBE A;  2ZN7 A;  3RSS A;  1LIK A;  3VAS A;  1WYE A;  4JKS A;  3AWG A;  3BGK A;  3PZS A;  3NRS A;  4N08 A;  2HNQ A;  2AX3 A;  2H4G A;  2Y66 A;  2FV7 A;  2NLK A;  3PMO A;  1EEO A;  2BV5 A;  3RO4 A;  5BYE A;  2HB1 A;  2Q05 A;  2CMA A;  2QDP A;  3BRH A;  4WU2 A;  5F11 A;  2CM2 A;  1G4U S;  2Y2F A;  3F9B A;  2CFV A;  4KAD A;  3OMH A;  3B1R A;  2JG5 A;  2YYB A;  3NM3 A;  4CVL A;  2XPC A;  5C3Y A;  2NV5 A;  2NT2 A;  1LIO A;  1TD2 A;  4OHL A;  1YTW A;  3QCB A;  2F02 A;  5C40 A;  3IN1 A;  3QCD A;  4K9C A;  4GFU A;  5KA1 A;  1LIJ A;  2VAR A;  4JMK A;  4XF7 A;  2DCN A;  3RU3 A;  4BJO A;  5B6A A;  2GC6 A;  2E0T A;  5BYC A;  2CMC A;  2P6X A;  3D1O A;  3HN7 A;  3GO6 A;  2GCB A;  3IE7 A;  2WGP A;  2JG1 A;  4KAN A;  2B49 A;  3QCL A;  4LBX A;  1I57 A;  3QKP A;  3B7O A;  3RT9 A;  5A5E A;  4YAA A;  3ZM0 A;  3DZV A;  1V1A A;  4WJM A;  3ZS7 A;  2B4P A;  3QCJ A;  2VEV A;  3D44 A;  1PTU A;  4O1L A;  3LJ8 A;  3RRE A;  2JFG A;  2A8B A;  4E8Y A;  5GTJ A;  1ESQ A;  5IBS A;  2I6I A;  3F41 A;  4QBW A;  4WU3 A;  5K22 A;  3V0I A;  2QHP A;  2I6P A;  5EHP A;  4GFV A;  3H49 A;  3WSH A;  2JFF A;  3WSD A;  2FJN A;  4IWG A;  4EOH A;  2HC2 A;  3BLU A;  3JUL A;  4QDI A;  2G59 A;  3RT7 A;  4OHH A;  3QCN A;  2BIJ A;  2QEP A;  3MBH A;  2I4E A;  2NWH A;  3U96 A;  1TYY A;  4N09 A;  1Q6T A;  2A3K A;  3LK7 A;  3EEQ A;  1OHC A;  2X5O A;  2B4O A;  4GRY A;  1G4W R;  1YN9 A;  3O3L A;  2HCM A;  3O4S A;  3LOO A;  4RDD A;  2GJT A;  1GC5 A;  4GS0 A;  2QBQ A;  4RHG A;  3KEU A;  1FGS A;  2I6M A;  3BF5 A;  2P4D A;  5AWX A;  3RQ8 A;  4OHI A;  2AZR A;  1XM2 A;  4KYR A;  3F81 A;  1T48 A;  1T49 A;  3WSG A;  2YDU A;  3RTC A;  1Q6M A;  2R0B A;  1RKD A;  5EHR A;  1XBO A;  1V1S A;  3RO1 A;  5EY7 A;  1NMP A;  2C7S A;  2H4V A;  2I6J A;  3I3Y A;  3D1H A;  3NC9 A;  3LJS A;  4EBU A;  2RBC A;  1MKP A;  2HY3 A;  2J16 B;  1YGJ A;  4OHE A;  2QBR A;  5KA9 A;  3UQD A;  3RGQ A;  4IWM A;  4S1I B;  3O5X A;  3H2X A;  2PKN A;  4ICZ A;  2RF6 A;  5KA4 A;  2HQQ A;  2I75 A;  3QAI A;  4LC4 A;  1EKQ A;  1W7K A;  1YGR A;  5KA7 A;  1ZCL A;  4XF6 A;  1JXH A;  4H34 A;  1Q1M A;  4GE6 A;  4YWR A;  4C5N A;  1G7F A;  4WOH A;  1NZ7 A;  1BZJ A;  4S1M A;  3RZ2 A;  2H02 A;  3EH0 A;  2QCV A;  1L2L A;  3HPD A;  2BZL A;  1FPZ A;  2I5X A;  3CWE A;  2F70 A;  3RTE A;  1KAV A;  4O1G A;  2PQ5 A;  3V0E A;  1UB0 A;  3GBU A;  2QDC A;  1KNX A;  1WRM A;  2PA5 A;  4GE2 A;  1FPR A;  3D9C A;  1OEM X;  4QAH A;  2CNH A;  3QCZ A;  4B04 A;  2XTB A;  4NYH A;  1V19 A;  1NO6 A;  4IHG A;  5M43 A;  3I7Z A;  1YTN A;  3GXG A;  1C83 A;  2F6Z A;  2GP0 A;  2IOJ A;  3NL2 A;  3QKQ A;  3D1Q A;  1Q6N A;  3DRW A;  1RK2 A;  4E79 A;  1X24 A;  2VEU A;  3S3F A;  1RXD A;  3EU0 A;  3UQE A;  2VEX A;  2DDO A;  4MBB A;  1E8C A;  4DU5 A;  3WSF A;  3NM1 A;  2NZ6 A;  4IHF A;  1YZ4 A;  4K8K A;  4BUC A;  4GWF A;  2AJP A;  3RPH A;  4D3R A;  1U2X A;  5CM5 A;  5COJ A;  1PYN A;  4E8W A;  2CMB A;  1YHJ A;  1VI9 A;  3NL5 A;  1ESJ A;  3OTX A;  4K8C A;  2F71 A;  3RTD A;  3RGO A;  2PT0 A;  5KA8 A;  1VK4 A;  4GM6 A;  3RSQ A;  5TQI A;  4GE5 A;  3NBV A;  1NMO A;  2F6Y A;  2J17 A;  3RQQ A;  2JJD A;  5BUG A;  4QF5 A;  2IU8 A;  1LQF A;  4C13 A;  1VHR A;  4JMJ A;  2ABQ A;  4RH9 A;  3GO7 A;  3EMU A;  4DC3 A;  3NCA A;  2Y1O A;  5KAC A;  1PTV A;  2BGE A;  3B1Q A;  1LHP A;  2Y67 A;  4KI9 A;  1RPM A;  2CNI A;  3IBQ A;  2CM7 A;  4AZ1 A;  4D3Q A;  5J8R A;  1G1H A;  1BX4 A;  2QBP A;  3QCH A;  1YGK A;  2VTD A;  2I5B A;  2AB8 A;  3UAG A;  4B8S A;  3LHX A;  5K24 A;  2UAG A;  1LHR A;  5KAA A;  1LII A;  3UQ6 A;  2A9Y A;  2OZ5 A;  3HIC A;  3CM3 A;  2WJP A;  3MVN A;  2H4K A;  2HLZ A;  1C84 A;  1C3Q A;  3MMJ A;  5IBM A;  2I3R A;  3K5W A;  3SR9 A;  3ZMQ A;  4H1O A;  2GCA A;  3B3L A;  3RRJ A;  3RS8 A;  1OET A;  4EUM A;  5BYF A;  2AWD A;  2B07 A;  3S3K A;  3S4O A;  1NWL A;  4UAG A;  4IHH A;  3V0D A;  2VTE A;  3EWM A;  2R3E A;  3ZM2 A;  1C87 A;  4JKU A;  2ABS A;  1WAX A;  1C88 A;  1V1B A;  4U7X A;  1Q6J A;  4RKK A;  4S1H A;  1OEU A;  5K23 A;  3ZM5 A;  1EKK A;  2IU9 A;  3IKH A;  4YR8 B;  4BPC A;  4HJP A;  1G1G A;  2PI7 A;  3F9A A;  2QDM A;  4IKC A;  1RFV A;  2FH7 A;  1TZ3 A;  3PYZ A;  2PKF A;  4I8N A;  1GFY A;  2MBC A;  1E0D A;  3A5J A;  2BGD A;  1QXK A;  3RM5 A;  1GWZ A;  2I6O A;  1YFO A;  5KA2 A;  3ZV2 A;  1PA1 A;  2CM3 A;  4PVG A;  4X8F A;  1WCH A;  5KA3 A;  2C46 A;  1RKS A;  3RQ5 A;  2I1Y A;  3EZZ A;  4K93 A;  1P15 A;  2Q5R A;  4ZI4 A;  2I3U A;  1U26 A;  4GRZ A;  5BX1 A;  1C85 A;  1KO7 A;  3B1P A;  2I4G A;  4KYQ A;  3S4E A;  3NL6 A;  4ZRT A;  2YXU A;  4TVV A;  4RH5 A;  1C86 A;  2CM8 A;  2HXP A;  3I80 A;  4PVV A;  2AM2 A;  1GQT A;  4E3A A;  2ESB A;  2NTA A;  3M4U A;  3L31 A;  2AFB A;  3QA2 A;  2Q47 A;  5I6V A;  3WSI A;  1FQ1 A;  3B1N A;  3EAX A;  2Y68 A;  4OHD A;  2QBS A;  2DDM A;  3O4T A;  2VOS A;  4KAL A;  2FYW A;  3W4S A;  2NT7 A;  2QCJ A;  3RS9 A;  1O5Z A;  3HJ6 A;  3HYO A;  1OHE A;  2HW1 A;  5A5F A;  2ZMM A;  3Q92 A;  3NC2 A;  3S3E A;  4B8R A;  3RSF A;  3QCG A;  3Q1Y A;  3RTA A;  1ZCK A;  4QAP A;  3SME A;  3FHX A;  2CNG A;  3F99 A;  5CGE A;  2C49 A;  1YGU A;  2CNF A;  3N0A A;  3OLR A;  1SUG A;  4LCA A;  3NL3 A;  2F6F A;  2G6Z A;  3MBJ A;  5K9W A;  1GQY A;  3A5K A;  3RQ6 A;  4NWF A;  2YXT A;  2GC5 A;  1GQQ A;  2H03 A;  5C41 A; 
#chains in the Genus database with same CATH homology
 3N2A A;  2Y1O A;  3LK7 A;  2Y67 A;  2X5O A;  1W78 A;  2UUP A;  2VTD A;  4BUB A;  3UAG A;  1GG4 A;  2UAG A;  1FGS A;  1J6U A;  2WTZ A;  3MVN A;  2WJP A;  1UAG A;  4ZIY A;  4C12 A;  2AM1 A;  2GCA A;  2XJA A;  4IHH A;  4UAG A;  1JBV A;  1JBW A;  2VTE A;  3NRS A;  4CVM A;  2VOR A;  3ZM5 A;  2IU9 A;  2Y66 A;  1EEH A;  2IUA A;  1W7K A;  3PMO A;  3PYZ A;  3EH0 A;  1E0D A;  2JFH A;  4CVL A;  2XPC A;  2F00 A;  2GC6 A;  3QCZ A;  4CVK A;  3ZM6 A;  4IHG A;  3HN7 A;  2AM2 A;  2GCB A;  4E79 A;  1P3D A;  5A5E A;  2Y68 A;  1E8C A;  2UUO A;  2VOS A;  3ZL8 A;  4IHF A;  2JFG A;  4BUC A;  1O5Z A;  4HV4 A;  5A5F A;  1P31 A;  2JFF A;  3EAG A;  1GQY A;  4QDI A;  4QF5 A;  2IU8 A;  2GC5 A;  4C13 A;  1GQQ A;  4E75 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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