3ZM5A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
molecule tags Ligase
source organism Streptococcus pneumoniae r6
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
total genus 143
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm5A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm5A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm5A03
2UAGA 1E8CA 1W78A 5A5EA 3EAGA 2GCBA 3ZM6A 2GC5A 2X5OA 2Y68A 3ZM5A 4IHFA 3MVNA 4ZIYA 2JFHA 1GQQA 3PMOA 3N2AA 3HN7A 1JBVA 4CVMA 2VOSA 3QCZA 2Y66A 1W7KA 4BUCA 1UAGA 1JBWA 4CVLA 2XPCA 1J6UA 2Y67A 3LK7A 4HV4A 2XJAA 2VTDA 1GG4A 2UUPA 1E0DA 3UAGA 4QDIA 1O5ZA 4CVKA 4E79A 2UUOA 4UAGA 2VORA 2WTZA 1FGSA 1GQYA 2F00A 2WJPA 2GCAA 4C13A 2IU8A 2JFGA 1P3DA 4QF5A 2AM2A 2VTEA 2AM1A 3EH0A 2IUAA 1EEHA 4C12A 4IHGA 2JFFA 2IU9A 3NRSA 4E75A 4BUBA 4IHHA 5A5FA 3PYZA 3ZL8A 2Y1OA 2GC6A 1P31A
chains in the Genus database with same CATH superfamily
4NYHA 5TQIA 4RHGA 1V1SA 4OHDA 1UB0A 1YTWA 2F70A 1L2LA 2UAGA 2I75A 3LJ8A 1KAKA 1W78A 1OEOX 1RFTA 1LIIA 1G1HA 3NBVA 2B4UA 5KA1A 5EY7A 3RS9A 3B3LA 3RTGA 4RH9A 3LJSA 1QXKA 2FYWA 4E3AA 4JNBA 3NM1A 4XF7A 3S4EA 4IHFA 3JULA 4JJPA 3RSFA 3RSQA 1XBOA 2F6FA 3PMOA 4I8NA 1C86A 1G4US 3RGQA 4TVVA 3S3KA 4S1IB 4GM6A 4S1MA 2AJPA 1RFUA 3WSGA 3AWEA 4NWFA 2NT2A 1DGMA 2CNIA 2VEUA 1T4JA 2A8BA 3RQXA 2YDUA 1YFOA 5K9WA 2C46A 1W7KA 3O5XA 2F6VA 3QCLA 3RO1A 3N1CA 4C5LA 1VM7A 4EUMA 5M43A 1G4WR 2B3OA 3BLTA 2AB8A 3B1PA 4O1LA 4E8YA 3VASA 5C3YA 1XM2A 3RQQA 1ZCKA 3QAIA 4B04A 3I80A 2R3BA 1NO6A 1PA9A 1D5RA 2GWOA 2I4EA 3A5JA 3EB1A 3OTXA 3RT9A 3WSEA 3CQDA 1G7FA 1KAVA 4OHLA 2PKKA 4QBWA 2QCJA 1YGRA 2VARA 3IE7A 4GRYA 5EHRA 2CM2A 1A5YA 1GC5A 1ZC0A 1TYYA 3KZHA 1C88A 1Q1MA 2JJDA 3AWFA 3GO6A 4R0TA 4QAPA 1RK2A 3F81A 2QBSA 3NL5A 4HRFA 1MKPA 3SMEA 2CNHA 2HW1A 3CM3A 4GE5A 4KAHA 2VORA 2WTZA 4LC4A 3GBUA 3LKIA 1KO7A 3B1RA 2AZRA 2F6ZA 2Y2FA 4GS0A 4U7XA 4AZ1A 2CM7A 1TD2A 4D3PA 5BX1A 4NX8A 3RRFA 2I5BA 3RTCA 2DXPA 1SUGA 1FQ1A 2IOJA 3DZVA 4KYRA 2CFVA 2F71A 1JXHA 2V78A 5CGAA 1Q6PA 4JMKA 5LXQB 3IBQA 4PVGA 4PYHA 1GFYA 2MBCA 5KA2A 3RS8A 4C5NA 3S3FA 3EH0A 2AM1A 3K9EA 2IUAA 4E69A 3RY7A 2VEYA 5KA9A 3QCDA 4RI5A 3MOZA 1PXHA 3V0HA 3KD6A 2J16A 3B1QA 2B4OA 5KA8A 2FJMA 3FHXA 1JXIA 3LHXA 1I9TA 3QCNA 2IMGA 3D1QA 4JBCA 4KI9A 1YWFA 2I6PA 1U2XA 2HCMA 2GC6A 1OEVA 5KA4A 2DDOA 1U24A 3UMOA 4E84A 3RRBA 4DC3A 3QCJA 5KABA 3RQ5A 4PVVA 5CGEA 3Q1YA 3EAGA 3KEUA 2GCBA 3O4SA 1BZCA 3QCKA 5MMZB 1TZ3A 2BGDA 3V0GA 2I6IA 3NL2A 4D3QA 5KA0A 4ZRTA 2JFHA 4K8CA 2CNFA 3V0JA 3RPHA 2H02A 1QZ0A 5EHPA 4E8ZA 1OHEA 1PTYA 3D42A 2BZLA 3EAXA 3U96A 2HQQA 2Q5RA 4CVMA 5KAAA 1WYEA 4B8RA 1OHDA 3RQ6A 2HVLA 2M3VA 2FV7A 2AX3A 4B8SA 4EOHA 1C3QA 1LIJA 2Q47A 2QHPA 3QCZA 2Y66A 3QCHA 1KYHA 3F41A 2ABSA 2H04A 4YL5A 3O4TA 2F7KA 1PTUA 1Q6NA 3QA2A 1T48A 5KA7A 2H4GA 1PYNA 1OEUA 2I5XA 3CWEA 1YGJA 4R30A 4K8KA 1G1FA 2VEWA 4GFUA 3PZSA 4Y14A 2Y96A 2VTDA 3OMHA 1GG4A 1LARA 1C87A 2UUPA 1RPMA 3RTDA 3MBHA 1ECVA 2OUDA 4ERCA 1VHRA 5BZXA 3SR9A 3UAGA 3RTAA 5EYNA 2A9YA 1UA4A 1ZZWA 4QDIA 4E8WA 3B7OA 3PS5A 4WU2A 1R6HA 3RO4A 5J8RA 5C3ZA 2CMAA 2NLKA 2PSZA 1NMOA 3WSFA 1RKAA 2FJNA 1OEMX 3QCGA 4KBEA 4GWFA 2PQ5A 2J17A 1BZHA 2PT0A 2PKFA 2QBRA 2CNGA 2B49A 1GQYA 1YGKA 2R3EA 3RM5A 1Q6JA 2F46A 2F00A 2SHPA 3NM3A 4JKUA 1KNXA 2C7SA 3O4UA 2QDPA 2CJZA 2CM3A 3IH0A 4JMJA 3MMJA 1V3AA 4QF5A 3F9AA 2AFBA 4K93A 1NNYA 4QUNA 3KTNA 2QEPA 3BM8A 1EEHA 4YAAA 4OHEA 2NV5A 1J4XA 1PTVA 1Q6MA 2NTAA 3H49A 4IHGA 1YPTA 4RI4A 4YR8B 2NT7A 2QCTA 2IU9A 2A9ZA 4ICZA 3QCCA 5C40A 4BUBA 2HC1A 3GO7A 3ZS7A 3O3LA 1U26A 4HJQA 5A5FA 2DDWA 4X8FA 4KADA 3VAQA 2CMCA 1P31A 4NWGA 3IKHA 1LHPA 1NL9A 4OHIA 1E8CA 4EBUA 5BUGA 3UMPA 4C5KA 3RTBA 3V0DA 2F6WA 3D1HA 1BX4A 3RQ2A 2GC5A 3V0FA 3A5KA 2X5OA 2Y68A 2HY3A 2DDMA 4K8TA 2YYBA 3QCIA 2E0TA 3ZM5A 3RREA 3L2BA 3MVNA 4ZIYA 3GXGA 2F02A 4DU5A 4LCAA 1OHCA 3H74A 4XF6A 2I4GA 3N2AA 4C5MA 5BYDA 2G59A 1JBVA 2QBPA 4LBXA 3RRJA 1V1AA 1YN9A 2DCNA 3BF5A 2VOSA 2VEVA 4IWMA 5TRWA 3Q92A 3HPDA 3GXHA 4QUMA 1X24A 3HICA 3EEQA 2Q05A 3RPZA 1JBWA 2QCVA 4CVLA 1EKKA 4WJMA 1WCHA 2P6XA 3ZM2A 3ZM0A 4XCKA 1YTNA 1VK4A 1LQFA 3NL6A 4UBEA 2H4KA 2I1YA 3LK7A 5COJA 4ZN5A 1NMPA 2YXUA 2C4EA 3OLRA 2GP0A 3RT7A 2PI7A 3W4SA 2AHSA 1ONYA 1E0DA 1FPRA 3B1NA 2B4PA 4GFVA 2JG1A 2I42A 3MBJA 2OOQA 1L8KA 5K25A 1WAXA 2CM8A 3RGOA 3EZZA 2AJRA 1RXDA 2R0BA 3V0EA 4CVKA 3ZM3A 2AWDA 4E79A 1Q6SA 4UAGA 1JLNA 2HXPA 2YXTA 1FGSA 4O1GA 2PA5A 1ESQA 3HJ6A 5B6AA 2I4HA 1FPZA 2RF6A 1YZ4A 4C5JA 2WJPA 3D1OA 2HNPA 4C13A 5F11A 3D9CA 2I6OA 5KA3A 2JFGA 1P3DA 1TZ6A 1YTSA 1C83A 2F6TA 2H03A 4LBGA 2AM2A 2VTEA 1XXPA 2CNEA 5HDEA 2I3UA 4DGPA 2JFFA 1LYVA 4RH5A 2GJTA 3NRSA 3I7ZA 4E75A 4EN4A 3UQEA 2BGEA 4IHHA 2ZN7A 3QKPA 2G6ZA 3F9BA 3EWMA 4K8PA 5BYFA 1LHRA 3DRWA 2QBQA 3PYZA 1PH0A 4Z6BA 1JF7A 1V19A 1LIKA 5K22A 4H1OA 4QAHA 3NL3A 2HNQA 2FH7A 5AWXA 3UQDA 3FHYA 1RFVA 4WU3A 3ZV2A 3AWGA 4RDDA 4K9CA 5A5EA 3S3HA 1BZJA 3I3YA 3QCEA 3ZM6A 4RKKA 3WSDA 4NNDA 3NMEA 1XXVA 2WGPA 5K24A 3WSHA 5F0ZA 1EEOA 2NZ6A 3NCAA 1P15A 4S0GA 4BPCA 3UQ6A 5BYEA 2XTBA 4Y2EA 1GQQA 2HC2A 2C49A 3RSGA 2QDCA 4GE6A 3HN7A 2B07A 5IBMA 1GQTA 1YHJA 2BIJA 2PKNA 2BV5A 1GWZA 2ESBA 1XRIA 4BJOA 4D3RA 3NC9A 3EMUA 5K23A 1Q6TA 3B1OA 1NZ7A 5I6VA 4WOHA 4ZI4A 2AA0A 5C41A 2NWHA 2JGVA 3RTEA 4DGXA 2RBCA 3S4OA 3BGKA 4BUCA 1UAGA 4KALA 2I6BA 1RKDA 1ESJA 3NBWA 2I6AA 2QDMA 3I36A 1PA1A 3RU2A 3RU3A 3V0IA 2XPCA 1J6UA 2Y67A 4HV4A 1ZCLA 3F99A 4R0SA 4N09A 2ZMMA 2XJAA 1EKQA 1OETA 2ABQA 3EU0A 3RQHA 2JG5A 1AAXA 3H2XA 4KYQA 3L31A 5KADA 3ZM1A 3IQ0A 5CM5A 4IWGA 2H4VA 3D44A 1ONZA 3LOOA 1YGUA 2I6JA 3RZ2A 5IBSA 5BYCA 3QCMA 2PKMA 2I3RA 1O5ZA 4HJPA 1L8GA 2B4SA 5KACA 4YWRA 1EENA 4XDAA 2HLZA 1NWLA 3PL2A 2A3KA 2OZ5A 5BZZA 3BLUA 2CMBA 2I6MA 2UUOA 1I57A 4MBBA 1U25A 3IN1A 1I9SA 1NWEA 3N0AA 5K9VA 3ZMPA 1C84A 3QKQA 1M3GA 3K5WA 4N08A 2GCAA 1WRMA 4GE2A 4WTYA 4GRZA 3ZMQA 4JKSA 2IU8A 3NC2A 1V1BA 3RSSA 2OC3A 2F6YA 3BRHA 1C85A 1OESA 2VEXA 3UBOA 4OHHA 3S3EA 3M4UA 4IKCA 1LIOA 4KANA 5GTJA 4S1IA 4S1HA 4C12A 1T49A 1RKSA 1G1GA 3UQ9A 1VI9A 4J51A 3QCFA 4H34A 1G7GA 2P4DA 3QCBA 3WSIA 3MOWA 4QBEA 3ZL8A 2J16B 4K9IA 2Y1OA 3RQ8A 2HB1A 3HYOA 1PTTA 2PBNA
chains in the Genus database with same CATH topology
2UAGA 1E8CA 1W78A 5A5EA 3EAGA 2GCBA 3ZM6A 2GC5A 2X5OA 2Y68A 3ZM5A 4IHFA 3MVNA 4ZIYA 2JFHA 1GQQA 3PMOA 3N2AA 3HN7A 1JBVA 4CVMA 2VOSA 3QCZA 2Y66A 1W7KA 4BUCA 1UAGA 1JBWA 4CVLA 2XPCA 1J6UA 2Y67A 3LK7A 4HV4A 2XJAA 2VTDA 1GG4A 2UUPA 1E0DA 3UAGA 4QDIA 1O5ZA 4CVKA 4E79A 2UUOA 4UAGA 2VORA 2WTZA 1FGSA 1GQYA 2F00A 2WJPA 2GCAA 4C13A 2IU8A 2JFGA 1P3DA 4QF5A 2AM2A 2VTEA 2AM1A 3EH0A 2IUAA 1EEHA 4C12A 4IHGA 2JFFA 2IU9A 3NRSA 4E75A 4BUBA 4IHHA 5A5FA 3PYZA 3ZL8A 2Y1OA 2GC6A 1P31A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UAG A;  1E8C A;  1W78 A;  5A5E A;  3EAG A;  2GCB A;  3ZM6 A;  2GC5 A;  2X5O A;  2Y68 A;  3ZM5 A;  4IHF A;  3MVN A;  4ZIY A;  2JFH A;  1GQQ A;  3PMO A;  3N2A A;  3HN7 A;  1JBV A;  4CVM A;  2VOS A;  3QCZ A;  2Y66 A;  1W7K A;  4BUC A;  1UAG A;  1JBW A;  4CVL A;  2XPC A;  1J6U A;  2Y67 A;  3LK7 A;  4HV4 A;  2XJA A;  2VTD A;  1GG4 A;  2UUP A;  1E0D A;  3UAG A;  4QDI A;  1O5Z A;  4CVK A;  4E79 A;  2UUO A;  4UAG A;  2VOR A;  2WTZ A;  1FGS A;  1GQY A;  2F00 A;  2WJP A;  2GCA A;  4C13 A;  2IU8 A;  2JFG A;  1P3D A;  4QF5 A;  2AM2 A;  2VTE A;  2AM1 A;  3EH0 A;  2IUA A;  1EEH A;  4C12 A;  4IHG A;  2JFF A;  2IU9 A;  3NRS A;  4E75 A;  4BUB A;  4IHH A;  5A5F A;  3PYZ A;  3ZL8 A;  2Y1O A;  2GC6 A;  1P31 A; 
#chains in the Genus database with same CATH topology
 4NYH A;  5TQI A;  4RHG A;  1V1S A;  4OHD A;  1UB0 A;  1YTW A;  2F70 A;  1L2L A;  2UAG A;  2I75 A;  3LJ8 A;  1KAK A;  1W78 A;  1OEO X;  1RFT A;  1LII A;  1G1H A;  3NBV A;  2B4U A;  5KA1 A;  5EY7 A;  3RS9 A;  3B3L A;  3RTG A;  4RH9 A;  3LJS A;  1QXK A;  2FYW A;  4E3A A;  4JNB A;  3NM1 A;  4XF7 A;  3S4E A;  4IHF A;  3JUL A;  4JJP A;  3RSF A;  3RSQ A;  1XBO A;  2F6F A;  3PMO A;  4I8N A;  1C86 A;  1G4U S;  3RGQ A;  4TVV A;  3S3K A;  4S1I B;  4GM6 A;  4S1M A;  2AJP A;  1RFU A;  3WSG A;  3AWE A;  4NWF A;  2NT2 A;  1DGM A;  2CNI A;  2VEU A;  1T4J A;  2A8B A;  3RQX A;  2YDU A;  1YFO A;  5K9W A;  2C46 A;  1W7K A;  3O5X A;  2F6V A;  3QCL A;  3RO1 A;  3N1C A;  4C5L A;  1VM7 A;  4EUM A;  5M43 A;  1G4W R;  2B3O A;  3BLT A;  2AB8 A;  3B1P A;  4O1L A;  4E8Y A;  3VAS A;  5C3Y A;  1XM2 A;  3RQQ A;  1ZCK A;  3QAI A;  4B04 A;  3I80 A;  2R3B A;  1NO6 A;  1PA9 A;  1D5R A;  2GWO A;  2I4E A;  3A5J A;  3EB1 A;  3OTX A;  3RT9 A;  3WSE A;  3CQD A;  1G7F A;  1KAV A;  4OHL A;  2PKK A;  4QBW A;  2QCJ A;  1YGR A;  2VAR A;  3IE7 A;  4GRY A;  5EHR A;  2CM2 A;  1A5Y A;  1GC5 A;  1ZC0 A;  1TYY A;  3KZH A;  1C88 A;  1Q1M A;  2JJD A;  3AWF A;  3GO6 A;  4R0T A;  4QAP A;  1RK2 A;  3F81 A;  2QBS A;  3NL5 A;  4HRF A;  1MKP A;  3SME A;  2CNH A;  2HW1 A;  3CM3 A;  4GE5 A;  4KAH A;  2VOR A;  2WTZ A;  4LC4 A;  3GBU A;  3LKI A;  1KO7 A;  3B1R A;  2AZR A;  2F6Z A;  2Y2F A;  4GS0 A;  4U7X A;  4AZ1 A;  2CM7 A;  1TD2 A;  4D3P A;  5BX1 A;  4NX8 A;  3RRF A;  2I5B A;  3RTC A;  2DXP A;  1SUG A;  1FQ1 A;  2IOJ A;  3DZV A;  4KYR A;  2CFV A;  2F71 A;  1JXH A;  2V78 A;  5CGA A;  1Q6P A;  4JMK A;  5LXQ B;  3IBQ A;  4PVG A;  4PYH A;  1GFY A;  2MBC A;  5KA2 A;  3RS8 A;  4C5N A;  3S3F A;  3EH0 A;  2AM1 A;  3K9E A;  2IUA A;  4E69 A;  3RY7 A;  2VEY A;  5KA9 A;  3QCD A;  4RI5 A;  3MOZ A;  1PXH A;  3V0H A;  3KD6 A;  2J16 A;  3B1Q A;  2B4O A;  5KA8 A;  2FJM A;  3FHX A;  1JXI A;  3LHX A;  1I9T A;  3QCN A;  2IMG A;  3D1Q A;  4JBC A;  4KI9 A;  1YWF A;  2I6P A;  1U2X A;  2HCM A;  2GC6 A;  1OEV A;  5KA4 A;  2DDO A;  1U24 A;  3UMO A;  4E84 A;  3RRB A;  4DC3 A;  3QCJ A;  5KAB A;  3RQ5 A;  4PVV A;  5CGE A;  3Q1Y A;  3EAG A;  3KEU A;  2GCB A;  3O4S A;  1BZC A;  3QCK A;  5MMZ B;  1TZ3 A;  2BGD A;  3V0G A;  2I6I A;  3NL2 A;  4D3Q A;  5KA0 A;  4ZRT A;  2JFH A;  4K8C A;  2CNF A;  3V0J A;  3RPH A;  2H02 A;  1QZ0 A;  5EHP A;  4E8Z A;  1OHE A;  1PTY A;  3D42 A;  2BZL A;  3EAX A;  3U96 A;  2HQQ A;  2Q5R A;  4CVM A;  5KAA A;  1WYE A;  4B8R A;  1OHD A;  3RQ6 A;  2HVL A;  2M3V A;  2FV7 A;  2AX3 A;  4B8S A;  4EOH A;  1C3Q A;  1LIJ A;  2Q47 A;  2QHP A;  3QCZ A;  2Y66 A;  3QCH A;  1KYH A;  3F41 A;  2ABS A;  2H04 A;  4YL5 A;  3O4T A;  2F7K A;  1PTU A;  1Q6N A;  3QA2 A;  1T48 A;  5KA7 A;  2H4G A;  1PYN A;  1OEU A;  2I5X A;  3CWE A;  1YGJ A;  4R30 A;  4K8K A;  1G1F A;  2VEW A;  4GFU A;  3PZS A;  4Y14 A;  2Y96 A;  2VTD A;  3OMH A;  1GG4 A;  1LAR A;  1C87 A;  2UUP A;  1RPM A;  3RTD A;  3MBH A;  1ECV A;  2OUD A;  4ERC A;  1VHR A;  5BZX A;  3SR9 A;  3UAG A;  3RTA A;  5EYN A;  2A9Y A;  1UA4 A;  1ZZW A;  4QDI A;  4E8W A;  3B7O A;  3PS5 A;  4WU2 A;  1R6H A;  3RO4 A;  5J8R A;  5C3Z A;  2CMA A;  2NLK A;  2PSZ A;  1NMO A;  3WSF A;  1RKA A;  2FJN A;  1OEM X;  3QCG A;  4KBE A;  4GWF A;  2PQ5 A;  2J17 A;  1BZH A;  2PT0 A;  2PKF A;  2QBR A;  2CNG A;  2B49 A;  1GQY A;  1YGK A;  2R3E A;  3RM5 A;  1Q6J A;  2F46 A;  2F00 A;  2SHP A;  3NM3 A;  4JKU A;  1KNX A;  2C7S A;  3O4U A;  2QDP A;  2CJZ A;  2CM3 A;  3IH0 A;  4JMJ A;  3MMJ A;  1V3A A;  4QF5 A;  3F9A A;  2AFB A;  4K93 A;  1NNY A;  4QUN A;  3KTN A;  2QEP A;  3BM8 A;  1EEH A;  4YAA A;  4OHE A;  2NV5 A;  1J4X A;  1PTV A;  1Q6M A;  2NTA A;  3H49 A;  4IHG A;  1YPT A;  4RI4 A;  4YR8 B;  2NT7 A;  2QCT A;  2IU9 A;  2A9Z A;  4ICZ A;  3QCC A;  5C40 A;  4BUB A;  2HC1 A;  3GO7 A;  3ZS7 A;  3O3L A;  1U26 A;  4HJQ A;  5A5F A;  2DDW A;  4X8F A;  4KAD A;  3VAQ A;  2CMC A;  1P31 A;  4NWG A;  3IKH A;  1LHP A;  1NL9 A;  4OHI A;  1E8C A;  4EBU A;  5BUG A;  3UMP A;  4C5K A;  3RTB A;  3V0D A;  2F6W A;  3D1H A;  1BX4 A;  3RQ2 A;  2GC5 A;  3V0F A;  3A5K A;  2X5O A;  2Y68 A;  2HY3 A;  2DDM A;  4K8T A;  2YYB A;  3QCI A;  2E0T A;  3ZM5 A;  3RRE A;  3L2B A;  3MVN A;  4ZIY A;  3GXG A;  2F02 A;  4DU5 A;  4LCA A;  1OHC A;  3H74 A;  4XF6 A;  2I4G A;  3N2A A;  4C5M A;  5BYD A;  2G59 A;  1JBV A;  2QBP A;  4LBX A;  3RRJ A;  1V1A A;  1YN9 A;  2DCN A;  3BF5 A;  2VOS A;  2VEV A;  4IWM A;  5TRW A;  3Q92 A;  3HPD A;  3GXH A;  4QUM A;  1X24 A;  3HIC A;  3EEQ A;  2Q05 A;  3RPZ A;  1JBW A;  2QCV A;  4CVL A;  1EKK A;  4WJM A;  1WCH A;  2P6X A;  3ZM2 A;  3ZM0 A;  4XCK A;  1YTN A;  1VK4 A;  1LQF A;  3NL6 A;  4UBE A;  2H4K A;  2I1Y A;  3LK7 A;  5COJ A;  4ZN5 A;  1NMP A;  2YXU A;  2C4E A;  3OLR A;  2GP0 A;  3RT7 A;  2PI7 A;  3W4S A;  2AHS A;  1ONY A;  1E0D A;  1FPR A;  3B1N A;  2B4P A;  4GFV A;  2JG1 A;  2I42 A;  3MBJ A;  2OOQ A;  1L8K A;  5K25 A;  1WAX A;  2CM8 A;  3RGO A;  3EZZ A;  2AJR A;  1RXD A;  2R0B A;  3V0E A;  4CVK A;  3ZM3 A;  2AWD A;  4E79 A;  1Q6S A;  4UAG A;  1JLN A;  2HXP A;  2YXT A;  1FGS A;  4O1G A;  2PA5 A;  1ESQ A;  3HJ6 A;  5B6A A;  2I4H A;  1FPZ A;  2RF6 A;  1YZ4 A;  4C5J A;  2WJP A;  3D1O A;  2HNP A;  4C13 A;  5F11 A;  3D9C A;  2I6O A;  5KA3 A;  2JFG A;  1P3D A;  1TZ6 A;  1YTS A;  1C83 A;  2F6T A;  2H03 A;  4LBG A;  2AM2 A;  2VTE A;  1XXP A;  2CNE A;  5HDE A;  2I3U A;  4DGP A;  2JFF A;  1LYV A;  4RH5 A;  2GJT A;  3NRS A;  3I7Z A;  4E75 A;  4EN4 A;  3UQE A;  2BGE A;  4IHH A;  2ZN7 A;  3QKP A;  2G6Z A;  3F9B A;  3EWM A;  4K8P A;  5BYF A;  1LHR A;  3DRW A;  2QBQ A;  3PYZ A;  1PH0 A;  4Z6B A;  1JF7 A;  1V19 A;  1LIK A;  5K22 A;  4H1O A;  4QAH A;  3NL3 A;  2HNQ A;  2FH7 A;  5AWX A;  3UQD A;  3FHY A;  1RFV A;  4WU3 A;  3ZV2 A;  3AWG A;  4RDD A;  4K9C A;  5A5E A;  3S3H A;  1BZJ A;  3I3Y A;  3QCE A;  3ZM6 A;  4RKK A;  3WSD A;  4NND A;  3NME A;  1XXV A;  2WGP A;  5K24 A;  3WSH A;  5F0Z A;  1EEO A;  2NZ6 A;  3NCA A;  1P15 A;  4S0G A;  4BPC A;  3UQ6 A;  5BYE A;  2XTB A;  4Y2E A;  1GQQ A;  2HC2 A;  2C49 A;  3RSG A;  2QDC A;  4GE6 A;  3HN7 A;  2B07 A;  5IBM A;  1GQT A;  1YHJ A;  2BIJ A;  2PKN A;  2BV5 A;  1GWZ A;  2ESB A;  1XRI A;  4BJO A;  4D3R A;  3NC9 A;  3EMU A;  5K23 A;  1Q6T A;  3B1O A;  1NZ7 A;  5I6V A;  4WOH A;  4ZI4 A;  2AA0 A;  5C41 A;  2NWH A;  2JGV A;  3RTE A;  4DGX A;  2RBC A;  3S4O A;  3BGK A;  4BUC A;  1UAG A;  4KAL A;  2I6B A;  1RKD A;  1ESJ A;  3NBW A;  2I6A A;  2QDM A;  3I36 A;  1PA1 A;  3RU2 A;  3RU3 A;  3V0I A;  2XPC A;  1J6U A;  2Y67 A;  4HV4 A;  1ZCL A;  3F99 A;  4R0S A;  4N09 A;  2ZMM A;  2XJA A;  1EKQ A;  1OET A;  2ABQ A;  3EU0 A;  3RQH A;  2JG5 A;  1AAX A;  3H2X A;  4KYQ A;  3L31 A;  5KAD A;  3ZM1 A;  3IQ0 A;  5CM5 A;  4IWG A;  2H4V A;  3D44 A;  1ONZ A;  3LOO A;  1YGU A;  2I6J A;  3RZ2 A;  5IBS A;  5BYC A;  3QCM A;  2PKM A;  2I3R A;  1O5Z A;  4HJP A;  1L8G A;  2B4S A;  5KAC A;  4YWR A;  1EEN A;  4XDA A;  2HLZ A;  1NWL A;  3PL2 A;  2A3K A;  2OZ5 A;  5BZZ A;  3BLU A;  2CMB A;  2I6M A;  2UUO A;  1I57 A;  4MBB A;  1U25 A;  3IN1 A;  1I9S A;  1NWE A;  3N0A A;  5K9V A;  3ZMP A;  1C84 A;  3QKQ A;  1M3G A;  3K5W A;  4N08 A;  2GCA A;  1WRM A;  4GE2 A;  4WTY A;  4GRZ A;  3ZMQ A;  4JKS A;  2IU8 A;  3NC2 A;  1V1B A;  3RSS A;  2OC3 A;  2F6Y A;  3BRH A;  1C85 A;  1OES A;  2VEX A;  3UBO A;  4OHH A;  3S3E A;  3M4U A;  4IKC A;  1LIO A;  4KAN A;  5GTJ A;  4S1I A;  4S1H A;  4C12 A;  1T49 A;  1RKS A;  1G1G A;  3UQ9 A;  1VI9 A;  4J51 A;  3QCF A;  4H34 A;  1G7G A;  2P4D A;  3QCB A;  3WSI A;  3MOW A;  4QBE A;  3ZL8 A;  2J16 B;  4K9I A;  2Y1O A;  3RQ8 A;  2HB1 A;  3HYO A;  1PTT A;  2PBN A; 
#chains in the Genus database with same CATH homology
 2UAG A;  1E8C A;  1W78 A;  5A5E A;  3EAG A;  2GCB A;  3ZM6 A;  2GC5 A;  2X5O A;  2Y68 A;  3ZM5 A;  4IHF A;  3MVN A;  4ZIY A;  2JFH A;  1GQQ A;  3PMO A;  3N2A A;  3HN7 A;  1JBV A;  4CVM A;  2VOS A;  3QCZ A;  2Y66 A;  1W7K A;  4BUC A;  1UAG A;  1JBW A;  4CVL A;  2XPC A;  1J6U A;  2Y67 A;  3LK7 A;  4HV4 A;  2XJA A;  2VTD A;  1GG4 A;  2UUP A;  1E0D A;  3UAG A;  4QDI A;  1O5Z A;  4CVK A;  4E79 A;  2UUO A;  4UAG A;  2VOR A;  2WTZ A;  1FGS A;  1GQY A;  2F00 A;  2WJP A;  2GCA A;  4C13 A;  2IU8 A;  2JFG A;  1P3D A;  4QF5 A;  2AM2 A;  2VTE A;  2AM1 A;  3EH0 A;  2IUA A;  1EEH A;  4C12 A;  4IHG A;  2JFF A;  2IU9 A;  3NRS A;  4E75 A;  4BUB A;  4IHH A;  5A5F A;  3PYZ A;  3ZL8 A;  2Y1O A;  2GC6 A;  1P31 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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