1PDRA

Crystal structure of the third pdz domain from the human homolog of discs large protein
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
96
structure length
96
Chain Sequence
ITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRQHA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a PDZ domain.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords HUMAN DISCS LARGE PROTEIN
total genus 22
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 1996-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 1pdrA00
1YBOA 5GNDA 4E34A 5FB8C 3VQGA 5HEYA 1N7FA 1OBZA 2DM8A 2DC2A 1QAUA 1FC6A 3CS0A 4L8NA 2YUBA 2QKUA 3PV2A 2PA1A 1UF1A 1RGRA 2IWOA 1UJUA 4R2ZA 3SFJA 1ZUBA 3QIKA 2LUIA 3DJ1A 1T2MA 1KEFA 1X5QA 3QJMA 5HETA 1QAVA 3WKLA 2L4TA 2M0UA 2YT7A 1WF8A 3TSZA 1WFVA 1P1DA 3HPMA 2MX6A 4REYA 1N99A 3SHWA 2I4SA 4YYXA 2CS5A 1PDRA 4K6YA 2VRFA 3GGEA 1N6DA 4P2AB 5JXBA 2JOAA 2KRGA 1V62A 4WYUA 3CBYA 2KV8A 5F3XA 2D92A 2ZPMA 2DKRA 3QDOA 2E7KA 3I4WA 4RI0A 5H3JA 3QJNA 2HE2A 3R68A 2H2CA 2P3WA 4HOPA 1WJLA 2PKUA 3GDSA 1GM1A 5A2PA 1TE0A 3I18A 3AXAA 4NMQA 3VQFA 2HE4A 3GCNA 3MH4A 4OAJA 1WI2A 1VA8A 2KOJA 2EDPA 3CH8A 2EEHA 5HF1A 1VCWA 1W9QA 4K76A 2OGPA 1N7TA 2EDVA 2LOBA 2PDZA 2R3YA 4P0CA 1OBXA 2DAZA 2X7ZA 4NMRA 4GVCA 1OBYA 2IWNA 1KY9A 2DJTA 2CSJA 1RGWA 5G1EA 1X5NA 4GVDA 4G69A 3RL8A 4Q2OA 2FE5A 4NXQA 1X45A 2K20A 1UEQA 3ID2A 2PZDA 2QT5A 4AMHA 3OTPA 4Q3HA 2EGNA 5GLJA 2ENOA 2F5YA 1UFXA 1UM7A 2JREA 1IHJA 3CYYA 4IC6A 4UU6A 2EXGA 2BYGA 2F0AA 2GZVA 1BE9A 4NMPA 1N7EA 4OEPA 2Q3GA 3LNYA 1UJDA 2EEGA 3OU0A 2DLUA 1MFGA 2VPHA 3PS4A 4Z8JA 2WL7A 2Z9IA 2G5MB 2KYLA 4JOPA 2FN5A 4Q2NA 3PDZA 5G1DA 2I6VA 2M3MA 2KPLA 3JXTA 4JOKA 3EGHC 2VSVA 1U39A 3PV4A 4K72A 3DJ3A 4JOHA 4NMVA 1XZ9A 3FY5A 1GQ5A 5B6LA 2PNTA 3EGGC 4PQWA 2M0TA 4UU5A 2L4SA 2UZCA 3DIWA 3GDUA 1NF3C 1W9OA 1L6OA 1Y7NA 2DMZA 2KL1A 5HFBA 2REYA 3RLEA 3K50A 3E17A 2V1WA 2CSSA 1RZXA 2RRMA 3B76A 2Q9VA 3ID4A 4NNLA 5E1YA 3SUZA 2EDZA 2OCSA 5HDYA 5D13A 1I92A 2EEIA 2K1ZA 4K75A 2OPGA 2ZPLA 2KJKA 2QBWA 2KOMA 3KZEA 4WYTA 1V1TA 3NGHA 3DJAA 5HFDA 2KBSA 2RCZA 1KWAA 1UEWA 5E11A 3BPUA 1QAVB 1Y8TA 1MC7A 4KFVA 1FC7A 2AWUA 4H11A 1MFLA 1TP5A 2H2BA 2YUYA 2QG1A 4JL7A 3GCOA 3LNXA 5F67A 4NMSA 3O46A 3R0HA 2FNEA 2M0VA 2IWPA 1I16A 3TSWA 2V90A 1WFGA 1X6DA 1LCYA 4Z33A 5HFEA 4MPAA 1IU0A 2DLSA 5I7ZA 1VB7A 2DB5A 1K32A 3QE1A 2L97A 1VAEA 1VJ6A 3QGLA 2W7RA 2KG2A 1UITA 2EGKA 2VSPA 4XHVA 2I0IA 2M10A 2VWRA 1G9OA 2JXOA 4HOPB 5HFCA 4JOFA 5E21A 1V5QA 4EDJA 2OS6A 4JOEA 1WI4A 1N6FA 2KPKA 1UHPA 1P1EA 1WG6A 2KQFA 2JINA 2OSGA 1B8QA 5DTHA 4GHNA 4JOJA 1Q3OA 2OZFA 5EZ0A 3MH6A 2KOHA 3R69A 1QLCA 2KJDA 2I0LA 3HPKA 3RL7A 4E35A 1OZIA 4NXPA 5FHTA 2HGAA 4LMMA 1WIFA 3STJA 2LA8A 2YT8A 4NMOA 2OMJA 2D8IA 3GJ9A 2EV8A 4FGMA 1RY4A 3O5NA 1WHAA 2VZ5A 5EYZA 1TP3A 4F8KA 2H3LA 1NTEA 4JORA 1FCFA 1GQ4A 4E3BA 2LC6A 1Z87A 2AWXA 1U37A 1N6EA 3KHFA 2AWWA 3CBZA 2I1NA 2JILA 1ZOKA 4OEOA 1Z86A 3L4FD 1UM1A 1UJVA 2O2TA 2EJYA 1WHDA 2LC7A 1SOTA 1SOZA 4O06A 2IWQA 1BFEA 1W9EA 3GDVA 1WF7A 5HF4A 2EAQA 1FC9A 3TSVA 2JWEA 3MH7A 2I04A 3TMHA 5E6PB 3NFKA 3HVQC 1D5GA 4K78A 2AINA 2PKTA 5HEBA 3PV5A 1Q3PA 2KAWA 1TQ3A 4N6XA 5HFFA 5HJ1A 1U3BA 4YDPA 2FCFA 1UEZA 2EHRA 4Q6SA 4JOGA 2Z17A 4Q2QA 2W4FA 2H3MA 3DORA 2M0ZA 4Q6HA 1IU2A 2G2LA 2QKTA 4NNMA 2YTWA 2EGOA 1M5ZA 4NMTA 4KFWA 2R4HA 3NFLA 5E22A 3CC0A 2QKVA 4NXRA 3WKMA 2D90A 2MHOA 3PDVA 1V5LA 3GSLA 1X8SA 1Q7XA 3SHUA 2EEJA 2OQSA 1R6JA 3K1RA 1V6BA 1X5RA 2KA9A 3CBXA 5HEDA 3QO6A 3ID1A 3ZRTA 3I1EA 1UEPA 2KJPA 3KZDA 4Q2PA 1WH1A 1U38A 3SOEA 3K82A 2JIKA 3ID3A
chains in the Genus database with same CATH superfamily
1YBOA 5GNDA 4E34A 5FB8C 3VQGA 5HEYA 1N7FA 1OBZA 2DM8A 2DC2A 1QAUA 1FC6A 3CS0A 4L8NA 2YUBA 2QKUA 3PV2A 2PA1A 1UF1A 1RGRA 2IWOA 1UJUA 4R2ZA 3SFJA 1ZUBA 3QIKA 2LUIA 3DJ1A 1T2MA 1KEFA 1X5QA 3QJMA 5HETA 1QAVA 3WKLA 2L4TA 2M0UA 2YT7A 1WF8A 3TSZA 1WFVA 1P1DA 3HPMA 2MX6A 4REYA 1N99A 3SHWA 2I4SA 4YYXA 2CS5A 1PDRA 4K6YA 2VRFA 3GGEA 5B42A 1N6DA 4P2AB 5JXBA 2JOAA 2KRGA 1V62A 4WYUA 3CBYA 2KV8A 5F3XA 2D92A 2ZPMA 2DKRA 3QDOA 2E7KA 3I4WA 4RI0A 5H3JA 3QJNA 2HE2A 3R68A 2H2CA 2P3WA 4HOPA 1WJLA 2PKUA 3GDSA 1GM1A 5A2PA 1TE0A 3I18A 3AXAA 4NMQA 3VQFA 2HE4A 3GCNA 3MH4A 4OAJA 1WI2A 1VA8A 2KOJA 2EDPA 3CH8A 2EEHA 5HF1A 1VCWA 1W9QA 4K76A 2OGPA 1N7TA 2EDVA 2LOBA 2PDZA 2R3YA 4P0CA 1OBXA 2DAZA 2X7ZA 4NMRA 4GVCA 1OBYA 2IWNA 1KY9A 2DJTA 2CSJA 1RGWA 5G1EA 1X5NA 4GVDA 4G69A 3RL8A 4Q2OA 2FE5A 4NXQA 1X45A 2K20A 1UEQA 2PZDA 2QT5A 3ID2A 4AMHA 3OTPA 4Q3HA 2EGNA 5GLJA 2ENOA 2F5YA 3KDGA 1UFXA 1UM7A 2JREA 1IHJA 3CYYA 4IC6A 4UU6A 2EXGA 2BYGA 2F0AA 2GZVA 1BE9A 4NMPA 1N7EA 4OEPA 2Q3GA 3LNYA 1UJDA 2EEGA 3OU0A 2DLUA 1MFGA 2VPHA 3PS4A 4Z8JA 2WL7A 2Z9IA 2G5MB 2KYLA 4JOPA 4FLNA 2FN5A 4Q2NA 3PDZA 5G1DA 2I6VA 2M3MA 2KPLA 3JXTA 4JOKA 3EGHC 5ILBA 2VSVA 1U39A 3PV4A 4K72A 3DJ3A 4JOHA 4NMVA 1XZ9A 3FY5A 1GQ5A 5B6LA 2PNTA 3EGGC 4PQWA 2M0TA 4UU5A 2L4SA 2UZCA 3DIWA 3GDUA 1NF3C 1W9OA 1L6OA 1Y7NA 2DMZA 2KL1A 5HFBA 2JSNA 2REYA 3RLEA 3K50A 3E17A 2V1WA 2CSSA 1RZXA 2RRMA 3B76A 2Q9VA 3ID4A 4NNLA 5E1YA 3SUZA 2EDZA 2OCSA 5HDYA 5D13A 1I92A 2EEIA 2K1ZA 4K75A 2OPGA 2ZPLA 2KJKA 2QBWA 2KOMA 3KZEA 4WYTA 1V1TA 3NGHA 3DJAA 5HFDA 2KBSA 2RCZA 1KWAA 1UEWA 5E11A 3BPUA 1QAVB 1Y8TA 1MC7A 4KFVA 1FC7A 4JJ0A 2AWUA 4H11A 1MFLA 1TP5A 2H2BA 2YUYA 2QG1A 4JL7A 3GCOA 3LNXA 5F67A 4NMSA 3O46A 3R0HA 2FNEA 2M0VA 2IWPA 1I16A 3TSWA 2V90A 1WFGA 1X6DA 1LCYA 4Z33A 5HFEA 4MPAA 1IU0A 1X9ZA 2DLSA 5I7ZA 1VB7A 2DB5A 1K32A 3QE1A 2L97A 1VAEA 1VJ6A 3QGLA 2W7RA 2KG2A 1UITA 2EGKA 2VSPA 4XHVA 2I0IA 2M10A 2VWRA 1G9OA 2JXOA 4HOPB 5HFCA 4JOFA 5E21A 1V5QA 4EDJA 2OS6A 4JOEA 1WI4A 1N6FA 2KPKA 1UHPA 1P1EA 1WG6A 2KQFA 2JINA 2OSGA 1B8QA 5DTHA 4GHNA 4JOJA 1Q3OA 2OZFA 5EZ0A 3MH6A 2KOHA 3R69A 1QLCA 2KJDA 2I0LA 3HPKA 3RL7A 4E35A 1OZIA 4NXPA 5FHTA 2HGAA 4LMMA 1WIFA 3STJA 2LA8A 2GEFA 2YT8A 3GABA 4NMOA 2OMJA 2D8IA 3GJ9A 2EV8A 4FGMA 1RY4A 3O5NA 1WHAA 2VZ5A 5EYZA 1TP3A 4F8KA 2H3LA 1NTEA 4JORA 1FCFA 1GQ4A 4E3BA 2LC6A 1Z87A 2AWXA 1U37A 1N6EA 3KHFA 2AWWA 3CBZA 2I1NA 2JILA 1ZOKA 4OEOA 1Z86A 3L4FD 1UM1A 1UJVA 2O2TA 2EJYA 1WHDA 2LC7A 1SOTA 1SOZA 4O06A 2IWQA 1BFEA 1W9EA 3GDVA 1WF7A 5HF4A 2EAQA 1FC9A 3TSVA 2JWEA 3MH7A 2I04A 3TMHA 5E6PB 3NFKA 3HVQC 1D5GA 4K78A 2AINA 2PKTA 5HEBA 3PV5A 1Q3PA 2KAWA 1TQ3A 4N6XA 5HFFA 5HJ1A 1U3BA 4YDPA 2FCFA 1UEZA 2EHRA 4Q6SA 4JOGA 2Z17A 3KDKA 4Q2QA 2W4FA 2H3MA 3DORA 2M0ZA 5IL9A 4Q6HA 1IU2A 2G2LA 2QKTA 4NNMA 2YTWA 2EGOA 1M5ZA 4NMTA 4KFWA 2R4HA 3NFLA 5E22A 3CC0A 2QKVA 4NXRA 3WKMA 2D90A 2MHOA 3PDVA 3NCVA 1V5LA 3GSLA 4JJ3A 1X8SA 1Q7XA 3SHUA 2EEJA 2OQSA 1R6JA 1V6BA 1X5RA 2KA9A 3CBXA 3K1RA 5HEDA 3QO6A 3ID1A 3ZRTA 3I1EA 1UEPA 2KJPA 3KZDA 4Q2PA 1WH1A 1U38A 3SOEA 3K82A 2JIKA 3ID3A
chains in the Genus database with same CATH topology
1YBOA 5GNDA 4E34A 5FB8C 3VQGA 5HEYA 1N7FA 1OBZA 2DM8A 2DC2A 1QAUA 1FC6A 3CS0A 4L8NA 2YUBA 2QKUA 3PV2A 2PA1A 1UF1A 1RGRA 2IWOA 1UJUA 4R2ZA 3SFJA 1ZUBA 3QIKA 2LUIA 3DJ1A 1T2MA 1KEFA 1X5QA 3QJMA 5HETA 1QAVA 3WKLA 2L4TA 2M0UA 2YT7A 1WF8A 3TSZA 1WFVA 1P1DA 3HPMA 2MX6A 4REYA 1N99A 3SHWA 2I4SA 4YYXA 2CS5A 1PDRA 4K6YA 2VRFA 3GGEA 5B42A 1N6DA 4P2AB 5JXBA 2JOAA 2KRGA 1V62A 4WYUA 3CBYA 2KV8A 5F3XA 2D92A 2ZPMA 2DKRA 3QDOA 2E7KA 3I4WA 4RI0A 5H3JA 3QJNA 2HE2A 3R68A 2H2CA 2P3WA 4HOPA 1WJLA 2PKUA 3GDSA 1GM1A 5A2PA 1TE0A 3I18A 3AXAA 4NMQA 3VQFA 2HE4A 3GCNA 3MH4A 4OAJA 1WI2A 1VA8A 2KOJA 2EDPA 3CH8A 2EEHA 5HF1A 1VCWA 1W9QA 4K76A 2OGPA 1N7TA 2EDVA 2LOBA 2PDZA 2R3YA 4P0CA 1OBXA 2DAZA 2X7ZA 4NMRA 4GVCA 1OBYA 2IWNA 1KY9A 2DJTA 2CSJA 1RGWA 5G1EA 1X5NA 4GVDA 4G69A 3RL8A 4Q2OA 2FE5A 4NXQA 1X45A 2K20A 1UEQA 2PZDA 2QT5A 3ID2A 4AMHA 3OTPA 4Q3HA 2EGNA 5GLJA 2ENOA 2F5YA 3KDGA 1UFXA 1UM7A 2JREA 1IHJA 3CYYA 4IC6A 4UU6A 2EXGA 2BYGA 2F0AA 2GZVA 1BE9A 4NMPA 1N7EA 4OEPA 2Q3GA 3LNYA 1UJDA 2EEGA 3OU0A 2DLUA 1MFGA 2VPHA 3PS4A 4Z8JA 2WL7A 2Z9IA 2G5MB 2KYLA 4JOPA 4FLNA 2FN5A 4Q2NA 3PDZA 5G1DA 2I6VA 2M3MA 2KPLA 3JXTA 4JOKA 3EGHC 5ILBA 2VSVA 1U39A 3PV4A 4K72A 3DJ3A 4JOHA 4NMVA 1XZ9A 3FY5A 1GQ5A 5B6LA 2PNTA 3EGGC 4PQWA 2M0TA 4UU5A 2L4SA 2UZCA 3DIWA 3GDUA 1NF3C 1W9OA 1L6OA 1Y7NA 2DMZA 2KL1A 5HFBA 2JSNA 2REYA 3RLEA 3K50A 3E17A 2V1WA 2CSSA 1RZXA 2RRMA 3B76A 2Q9VA 3ID4A 4NNLA 5E1YA 3SUZA 2EDZA 2OCSA 5HDYA 5D13A 1I92A 2EEIA 2K1ZA 4K75A 2OPGA 2ZPLA 2KJKA 2QBWA 2KOMA 3KZEA 4WYTA 1V1TA 3NGHA 3DJAA 5HFDA 2KBSA 2RCZA 1KWAA 1UEWA 5E11A 3BPUA 1QAVB 1Y8TA 1MC7A 4KFVA 1FC7A 4JJ0A 2AWUA 4H11A 1MFLA 1TP5A 2H2BA 2YUYA 2QG1A 4JL7A 3GCOA 3LNXA 5F67A 4NMSA 3O46A 3R0HA 2FNEA 2M0VA 2IWPA 1I16A 3TSWA 2V90A 1WFGA 1X6DA 1LCYA 4Z33A 5HFEA 4MPAA 1IU0A 1X9ZA 2DLSA 5I7ZA 1VB7A 2DB5A 1K32A 3QE1A 2L97A 1VAEA 1VJ6A 3QGLA 2W7RA 2KG2A 1UITA 2EGKA 2VSPA 4XHVA 2I0IA 2M10A 2VWRA 1G9OA 2JXOA 4HOPB 5HFCA 4JOFA 5E21A 1V5QA 4EDJA 2OS6A 4JOEA 1WI4A 1N6FA 2KPKA 1UHPA 1P1EA 1WG6A 2KQFA 2JINA 2OSGA 1B8QA 5DTHA 4GHNA 4JOJA 1Q3OA 2OZFA 5EZ0A 3MH6A 2KOHA 3R69A 1QLCA 2KJDA 2I0LA 3HPKA 3RL7A 4E35A 1OZIA 4NXPA 5FHTA 2HGAA 4LMMA 1WIFA 3STJA 2LA8A 2GEFA 2YT8A 3GABA 4NMOA 2OMJA 2D8IA 3GJ9A 2EV8A 4FGMA 1RY4A 3O5NA 1WHAA 2VZ5A 5EYZA 1TP3A 4F8KA 2H3LA 1NTEA 4JORA 1FCFA 1GQ4A 4E3BA 2LC6A 1Z87A 2AWXA 1U37A 1N6EA 3KHFA 2AWWA 3CBZA 2I1NA 2JILA 1ZOKA 4OEOA 1Z86A 3L4FD 1UM1A 1UJVA 2O2TA 2EJYA 1WHDA 2LC7A 1SOTA 1SOZA 4O06A 2IWQA 1BFEA 1W9EA 3GDVA 1WF7A 5HF4A 2EAQA 1FC9A 3TSVA 2JWEA 3MH7A 2I04A 3TMHA 5E6PB 3NFKA 3HVQC 1D5GA 4K78A 2AINA 2PKTA 5HEBA 3PV5A 1Q3PA 2KAWA 1TQ3A 4N6XA 5HFFA 5HJ1A 1U3BA 4YDPA 2FCFA 1UEZA 2EHRA 4Q6SA 4JOGA 2Z17A 3KDKA 4Q2QA 2W4FA 2H3MA 3DORA 2M0ZA 5IL9A 4Q6HA 1IU2A 2G2LA 2QKTA 4NNMA 2YTWA 2EGOA 1M5ZA 4NMTA 4KFWA 2R4HA 3NFLA 5E22A 3CC0A 2QKVA 4NXRA 3WKMA 2D90A 2MHOA 3PDVA 3NCVA 1V5LA 3GSLA 4JJ3A 1X8SA 1Q7XA 3SHUA 2EEJA 2OQSA 1R6JA 1V6BA 1X5RA 2KA9A 3CBXA 3K1RA 5HEDA 3QO6A 3ID1A 3ZRTA 3I1EA 1UEPA 2KJPA 3KZDA 4Q2PA 1WH1A 1U38A 3SOEA 3K82A 2JIKA 3ID3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YBO A;  5GND A;  4E34 A;  5FB8 C;  3VQG A;  5HEY A;  1N7F A;  1OBZ A;  2DM8 A;  2DC2 A;  1QAU A;  1FC6 A;  3CS0 A;  4L8N A;  2YUB A;  2QKU A;  3PV2 A;  2PA1 A;  1UF1 A;  1RGR A;  2IWO A;  1UJU A;  4R2Z A;  3SFJ A;  1ZUB A;  3QIK A;  2LUI A;  3DJ1 A;  1T2M A;  1KEF A;  1X5Q A;  3QJM A;  5HET A;  1QAV A;  3WKL A;  2L4T A;  2M0U A;  2YT7 A;  1WF8 A;  3TSZ A;  1WFV A;  1P1D A;  3HPM A;  2MX6 A;  4REY A;  1N99 A;  3SHW A;  2I4S A;  4YYX A;  2CS5 A;  1PDR A;  4K6Y A;  2VRF A;  3GGE A;  1N6D A;  4P2A B;  5JXB A;  2JOA A;  2KRG A;  1V62 A;  4WYU A;  3CBY A;  2KV8 A;  5F3X A;  2D92 A;  2ZPM A;  2DKR A;  3QDO A;  2E7K A;  3I4W A;  4RI0 A;  5H3J A;  3QJN A;  2HE2 A;  3R68 A;  2H2C A;  2P3W A;  4HOP A;  1WJL A;  2PKU A;  3GDS A;  1GM1 A;  5A2P A;  1TE0 A;  3I18 A;  3AXA A;  4NMQ A;  3VQF A;  2HE4 A;  3GCN A;  3MH4 A;  4OAJ A;  1WI2 A;  1VA8 A;  2KOJ A;  2EDP A;  3CH8 A;  2EEH A;  5HF1 A;  1VCW A;  1W9Q A;  4K76 A;  2OGP A;  1N7T A;  2EDV A;  2LOB A;  2PDZ A;  2R3Y A;  4P0C A;  1OBX A;  2DAZ A;  2X7Z A;  4NMR A;  4GVC A;  1OBY A;  2IWN A;  1KY9 A;  2DJT A;  2CSJ A;  1RGW A;  5G1E A;  1X5N A;  4GVD A;  4G69 A;  3RL8 A;  4Q2O A;  2FE5 A;  4NXQ A;  1X45 A;  2K20 A;  1UEQ A;  3ID2 A;  2PZD A;  2QT5 A;  4AMH A;  3OTP A;  4Q3H A;  2EGN A;  5GLJ A;  2ENO A;  2F5Y A;  1UFX A;  1UM7 A;  2JRE A;  1IHJ A;  3CYY A;  4IC6 A;  4UU6 A;  2EXG A;  2BYG A;  2F0A A;  2GZV A;  1BE9 A;  4NMP A;  1N7E A;  4OEP A;  2Q3G A;  3LNY A;  1UJD A;  2EEG A;  3OU0 A;  2DLU A;  1MFG A;  2VPH A;  3PS4 A;  4Z8J A;  2WL7 A;  2Z9I A;  2G5M B;  2KYL A;  4JOP A;  2FN5 A;  4Q2N A;  3PDZ A;  5G1D A;  2I6V A;  2M3M A;  2KPL A;  3JXT A;  4JOK A;  3EGH C;  2VSV A;  1U39 A;  3PV4 A;  4K72 A;  3DJ3 A;  4JOH A;  4NMV A;  1XZ9 A;  3FY5 A;  1GQ5 A;  5B6L A;  2PNT A;  3EGG C;  4PQW A;  2M0T A;  4UU5 A;  2L4S A;  2UZC A;  3DIW A;  3GDU A;  1NF3 C;  1W9O A;  1L6O A;  1Y7N A;  2DMZ A;  2KL1 A;  5HFB A;  2REY A;  3RLE A;  3K50 A;  3E17 A;  2V1W A;  2CSS A;  1RZX A;  2RRM A;  3B76 A;  2Q9V A;  3ID4 A;  4NNL A;  5E1Y A;  3SUZ A;  2EDZ A;  2OCS A;  5HDY A;  5D13 A;  1I92 A;  2EEI A;  2K1Z A;  4K75 A;  2OPG A;  2ZPL A;  2KJK A;  2QBW A;  2KOM A;  3KZE A;  4WYT A;  1V1T A;  3NGH A;  3DJA A;  5HFD A;  2KBS A;  2RCZ A;  1KWA A;  1UEW A;  5E11 A;  3BPU A;  1QAV B;  1Y8T A;  1MC7 A;  4KFV A;  1FC7 A;  2AWU A;  4H11 A;  1MFL A;  1TP5 A;  2H2B A;  2YUY A;  2QG1 A;  4JL7 A;  3GCO A;  3LNX A;  5F67 A;  4NMS A;  3O46 A;  3R0H A;  2FNE A;  2M0V A;  2IWP A;  1I16 A;  3TSW A;  2V90 A;  1WFG A;  1X6D A;  1LCY A;  4Z33 A;  5HFE A;  4MPA A;  1IU0 A;  2DLS A;  5I7Z A;  1VB7 A;  2DB5 A;  1K32 A;  3QE1 A;  2L97 A;  1VAE A;  1VJ6 A;  3QGL A;  2W7R A;  2KG2 A;  1UIT A;  2EGK A;  2VSP A;  4XHV A;  2I0I A;  2M10 A;  2VWR A;  1G9O A;  2JXO A;  4HOP B;  5HFC A;  4JOF A;  5E21 A;  1V5Q A;  4EDJ A;  2OS6 A;  4JOE A;  1WI4 A;  1N6F A;  2KPK A;  1UHP A;  1P1E A;  1WG6 A;  2KQF A;  2JIN A;  2OSG A;  1B8Q A;  5DTH A;  4GHN A;  4JOJ A;  1Q3O A;  2OZF A;  5EZ0 A;  3MH6 A;  2KOH A;  3R69 A;  1QLC A;  2KJD A;  2I0L A;  3HPK A;  3RL7 A;  4E35 A;  1OZI A;  4NXP A;  5FHT A;  2HGA A;  4LMM A;  1WIF A;  3STJ A;  2LA8 A;  2YT8 A;  4NMO A;  2OMJ A;  2D8I A;  3GJ9 A;  2EV8 A;  4FGM A;  1RY4 A;  3O5N A;  1WHA A;  2VZ5 A;  5EYZ A;  1TP3 A;  4F8K A;  2H3L A;  1NTE A;  4JOR A;  1FCF A;  1GQ4 A;  4E3B A;  2LC6 A;  1Z87 A;  2AWX A;  1U37 A;  1N6E A;  3KHF A;  2AWW A;  3CBZ A;  2I1N A;  2JIL A;  1ZOK A;  4OEO A;  1Z86 A;  3L4F D;  1UM1 A;  1UJV A;  2O2T A;  2EJY A;  1WHD A;  2LC7 A;  1SOT A;  1SOZ A;  4O06 A;  2IWQ A;  1BFE A;  1W9E A;  3GDV A;  1WF7 A;  5HF4 A;  2EAQ A;  1FC9 A;  3TSV A;  2JWE A;  3MH7 A;  2I04 A;  3TMH A;  5E6P B;  3NFK A;  3HVQ C;  1D5G A;  4K78 A;  2AIN A;  2PKT A;  5HEB A;  3PV5 A;  1Q3P A;  2KAW A;  1TQ3 A;  4N6X A;  5HFF A;  5HJ1 A;  1U3B A;  4YDP A;  2FCF A;  1UEZ A;  2EHR A;  4Q6S A;  4JOG A;  2Z17 A;  4Q2Q A;  2W4F A;  2H3M A;  3DOR A;  2M0Z A;  4Q6H A;  1IU2 A;  2G2L A;  2QKT A;  4NNM A;  2YTW A;  2EGO A;  1M5Z A;  4NMT A;  4KFW A;  2R4H A;  3NFL A;  5E22 A;  3CC0 A;  2QKV A;  4NXR A;  3WKM A;  2D90 A;  2MHO A;  3PDV A;  1V5L A;  3GSL A;  1X8S A;  1Q7X A;  3SHU A;  2EEJ A;  2OQS A;  1R6J A;  3K1R A;  1V6B A;  1X5R A;  2KA9 A;  3CBX A;  5HED A;  3QO6 A;  3ID1 A;  3ZRT A;  3I1E A;  1UEP A;  2KJP A;  3KZD A;  4Q2P A;  1WH1 A;  1U38 A;  3SOE A;  3K82 A;  2JIK A;  3ID3 A; 
#chains in the Genus database with same CATH topology
 1YBO A;  5GND A;  4E34 A;  5FB8 C;  3VQG A;  5HEY A;  1N7F A;  1OBZ A;  2DM8 A;  2DC2 A;  1QAU A;  1FC6 A;  3CS0 A;  4L8N A;  2YUB A;  2QKU A;  3PV2 A;  2PA1 A;  1UF1 A;  1RGR A;  2IWO A;  1UJU A;  4R2Z A;  3SFJ A;  1ZUB A;  3QIK A;  2LUI A;  3DJ1 A;  1T2M A;  1KEF A;  1X5Q A;  3QJM A;  5HET A;  1QAV A;  3WKL A;  2L4T A;  2M0U A;  2YT7 A;  1WF8 A;  3TSZ A;  1WFV A;  1P1D A;  3HPM A;  2MX6 A;  4REY A;  1N99 A;  3SHW A;  2I4S A;  4YYX A;  2CS5 A;  1PDR A;  4K6Y A;  2VRF A;  3GGE A;  5B42 A;  1N6D A;  4P2A B;  5JXB A;  2JOA A;  2KRG A;  1V62 A;  4WYU A;  3CBY A;  2KV8 A;  5F3X A;  2D92 A;  2ZPM A;  2DKR A;  3QDO A;  2E7K A;  3I4W A;  4RI0 A;  5H3J A;  3QJN A;  2HE2 A;  3R68 A;  2H2C A;  2P3W A;  4HOP A;  1WJL A;  2PKU A;  3GDS A;  1GM1 A;  5A2P A;  1TE0 A;  3I18 A;  3AXA A;  4NMQ A;  3VQF A;  2HE4 A;  3GCN A;  3MH4 A;  4OAJ A;  1WI2 A;  1VA8 A;  2KOJ A;  2EDP A;  3CH8 A;  2EEH A;  5HF1 A;  1VCW A;  1W9Q A;  4K76 A;  2OGP A;  1N7T A;  2EDV A;  2LOB A;  2PDZ A;  2R3Y A;  4P0C A;  1OBX A;  2DAZ A;  2X7Z A;  4NMR A;  4GVC A;  1OBY A;  2IWN A;  1KY9 A;  2DJT A;  2CSJ A;  1RGW A;  5G1E A;  1X5N A;  4GVD A;  4G69 A;  3RL8 A;  4Q2O A;  2FE5 A;  4NXQ A;  1X45 A;  2K20 A;  1UEQ A;  2PZD A;  2QT5 A;  3ID2 A;  4AMH A;  3OTP A;  4Q3H A;  2EGN A;  5GLJ A;  2ENO A;  2F5Y A;  3KDG A;  1UFX A;  1UM7 A;  2JRE A;  1IHJ A;  3CYY A;  4IC6 A;  4UU6 A;  2EXG A;  2BYG A;  2F0A A;  2GZV A;  1BE9 A;  4NMP A;  1N7E A;  4OEP A;  2Q3G A;  3LNY A;  1UJD A;  2EEG A;  3OU0 A;  2DLU A;  1MFG A;  2VPH A;  3PS4 A;  4Z8J A;  2WL7 A;  2Z9I A;  2G5M B;  2KYL A;  4JOP A;  4FLN A;  2FN5 A;  4Q2N A;  3PDZ A;  5G1D A;  2I6V A;  2M3M A;  2KPL A;  3JXT A;  4JOK A;  3EGH C;  5ILB A;  2VSV A;  1U39 A;  3PV4 A;  4K72 A;  3DJ3 A;  4JOH A;  4NMV A;  1XZ9 A;  3FY5 A;  1GQ5 A;  5B6L A;  2PNT A;  3EGG C;  4PQW A;  2M0T A;  4UU5 A;  2L4S A;  2UZC A;  3DIW A;  3GDU A;  1NF3 C;  1W9O A;  1L6O A;  1Y7N A;  2DMZ A;  2KL1 A;  5HFB A;  2JSN A;  2REY A;  3RLE A;  3K50 A;  3E17 A;  2V1W A;  2CSS A;  1RZX A;  2RRM A;  3B76 A;  2Q9V A;  3ID4 A;  4NNL A;  5E1Y A;  3SUZ A;  2EDZ A;  2OCS A;  5HDY A;  5D13 A;  1I92 A;  2EEI A;  2K1Z A;  4K75 A;  2OPG A;  2ZPL A;  2KJK A;  2QBW A;  2KOM A;  3KZE A;  4WYT A;  1V1T A;  3NGH A;  3DJA A;  5HFD A;  2KBS A;  2RCZ A;  1KWA A;  1UEW A;  5E11 A;  3BPU A;  1QAV B;  1Y8T A;  1MC7 A;  4KFV A;  1FC7 A;  4JJ0 A;  2AWU A;  4H11 A;  1MFL A;  1TP5 A;  2H2B A;  2YUY A;  2QG1 A;  4JL7 A;  3GCO A;  3LNX A;  5F67 A;  4NMS A;  3O46 A;  3R0H A;  2FNE A;  2M0V A;  2IWP A;  1I16 A;  3TSW A;  2V90 A;  1WFG A;  1X6D A;  1LCY A;  4Z33 A;  5HFE A;  4MPA A;  1IU0 A;  1X9Z A;  2DLS A;  5I7Z A;  1VB7 A;  2DB5 A;  1K32 A;  3QE1 A;  2L97 A;  1VAE A;  1VJ6 A;  3QGL A;  2W7R A;  2KG2 A;  1UIT A;  2EGK A;  2VSP A;  4XHV A;  2I0I A;  2M10 A;  2VWR A;  1G9O A;  2JXO A;  4HOP B;  5HFC A;  4JOF A;  5E21 A;  1V5Q A;  4EDJ A;  2OS6 A;  4JOE A;  1WI4 A;  1N6F A;  2KPK A;  1UHP A;  1P1E A;  1WG6 A;  2KQF A;  2JIN A;  2OSG A;  1B8Q A;  5DTH A;  4GHN A;  4JOJ A;  1Q3O A;  2OZF A;  5EZ0 A;  3MH6 A;  2KOH A;  3R69 A;  1QLC A;  2KJD A;  2I0L A;  3HPK A;  3RL7 A;  4E35 A;  1OZI A;  4NXP A;  5FHT A;  2HGA A;  4LMM A;  1WIF A;  3STJ A;  2LA8 A;  2GEF A;  2YT8 A;  3GAB A;  4NMO A;  2OMJ A;  2D8I A;  3GJ9 A;  2EV8 A;  4FGM A;  1RY4 A;  3O5N A;  1WHA A;  2VZ5 A;  5EYZ A;  1TP3 A;  4F8K A;  2H3L A;  1NTE A;  4JOR A;  1FCF A;  1GQ4 A;  4E3B A;  2LC6 A;  1Z87 A;  2AWX A;  1U37 A;  1N6E A;  3KHF A;  2AWW A;  3CBZ A;  2I1N A;  2JIL A;  1ZOK A;  4OEO A;  1Z86 A;  3L4F D;  1UM1 A;  1UJV A;  2O2T A;  2EJY A;  1WHD A;  2LC7 A;  1SOT A;  1SOZ A;  4O06 A;  2IWQ A;  1BFE A;  1W9E A;  3GDV A;  1WF7 A;  5HF4 A;  2EAQ A;  1FC9 A;  3TSV A;  2JWE A;  3MH7 A;  2I04 A;  3TMH A;  5E6P B;  3NFK A;  3HVQ C;  1D5G A;  4K78 A;  2AIN A;  2PKT A;  5HEB A;  3PV5 A;  1Q3P A;  2KAW A;  1TQ3 A;  4N6X A;  5HFF A;  5HJ1 A;  1U3B A;  4YDP A;  2FCF A;  1UEZ A;  2EHR A;  4Q6S A;  4JOG A;  2Z17 A;  3KDK A;  4Q2Q A;  2W4F A;  2H3M A;  3DOR A;  2M0Z A;  5IL9 A;  4Q6H A;  1IU2 A;  2G2L A;  2QKT A;  4NNM A;  2YTW A;  2EGO A;  1M5Z A;  4NMT A;  4KFW A;  2R4H A;  3NFL A;  5E22 A;  3CC0 A;  2QKV A;  4NXR A;  3WKM A;  2D90 A;  2MHO A;  3PDV A;  3NCV A;  1V5L A;  3GSL A;  4JJ3 A;  1X8S A;  1Q7X A;  3SHU A;  2EEJ A;  2OQS A;  1R6J A;  1V6B A;  1X5R A;  2KA9 A;  3CBX A;  3K1R A;  5HED A;  3QO6 A;  3ID1 A;  3ZRT A;  3I1E A;  1UEP A;  2KJP A;  3KZD A;  4Q2P A;  1WH1 A;  1U38 A;  3SOE A;  3K82 A;  2JIK A;  3ID3 A; 
#chains in the Genus database with same CATH homology
 1YBO A;  5GND A;  4E34 A;  5FB8 C;  3VQG A;  5HEY A;  1N7F A;  1OBZ A;  2DM8 A;  2DC2 A;  1QAU A;  1FC6 A;  3CS0 A;  4L8N A;  2YUB A;  2QKU A;  3PV2 A;  2PA1 A;  1UF1 A;  1RGR A;  2IWO A;  1UJU A;  4R2Z A;  3SFJ A;  1ZUB A;  3QIK A;  2LUI A;  3DJ1 A;  1T2M A;  1KEF A;  1X5Q A;  3QJM A;  5HET A;  1QAV A;  3WKL A;  2L4T A;  2M0U A;  2YT7 A;  1WF8 A;  3TSZ A;  1WFV A;  1P1D A;  3HPM A;  2MX6 A;  4REY A;  1N99 A;  3SHW A;  2I4S A;  4YYX A;  2CS5 A;  1PDR A;  4K6Y A;  2VRF A;  3GGE A;  5B42 A;  1N6D A;  4P2A B;  5JXB A;  2JOA A;  2KRG A;  1V62 A;  4WYU A;  3CBY A;  2KV8 A;  5F3X A;  2D92 A;  2ZPM A;  2DKR A;  3QDO A;  2E7K A;  3I4W A;  4RI0 A;  5H3J A;  3QJN A;  2HE2 A;  3R68 A;  2H2C A;  2P3W A;  4HOP A;  1WJL A;  2PKU A;  3GDS A;  1GM1 A;  5A2P A;  1TE0 A;  3I18 A;  3AXA A;  4NMQ A;  3VQF A;  2HE4 A;  3GCN A;  3MH4 A;  4OAJ A;  1WI2 A;  1VA8 A;  2KOJ A;  2EDP A;  3CH8 A;  2EEH A;  5HF1 A;  1VCW A;  1W9Q A;  4K76 A;  2OGP A;  1N7T A;  2EDV A;  2LOB A;  2PDZ A;  2R3Y A;  4P0C A;  1OBX A;  2DAZ A;  2X7Z A;  4NMR A;  4GVC A;  1OBY A;  2IWN A;  1KY9 A;  2DJT A;  2CSJ A;  1RGW A;  5G1E A;  1X5N A;  4GVD A;  4G69 A;  3RL8 A;  4Q2O A;  2FE5 A;  4NXQ A;  1X45 A;  2K20 A;  1UEQ A;  2PZD A;  2QT5 A;  3ID2 A;  4AMH A;  3OTP A;  4Q3H A;  2EGN A;  5GLJ A;  2ENO A;  2F5Y A;  3KDG A;  1UFX A;  1UM7 A;  2JRE A;  1IHJ A;  3CYY A;  4IC6 A;  4UU6 A;  2EXG A;  2BYG A;  2F0A A;  2GZV A;  1BE9 A;  4NMP A;  1N7E A;  4OEP A;  2Q3G A;  3LNY A;  1UJD A;  2EEG A;  3OU0 A;  2DLU A;  1MFG A;  2VPH A;  3PS4 A;  4Z8J A;  2WL7 A;  2Z9I A;  2G5M B;  2KYL A;  4JOP A;  4FLN A;  2FN5 A;  4Q2N A;  3PDZ A;  5G1D A;  2I6V A;  2M3M A;  2KPL A;  3JXT A;  4JOK A;  3EGH C;  5ILB A;  2VSV A;  1U39 A;  3PV4 A;  4K72 A;  3DJ3 A;  4JOH A;  4NMV A;  1XZ9 A;  3FY5 A;  1GQ5 A;  5B6L A;  2PNT A;  3EGG C;  4PQW A;  2M0T A;  4UU5 A;  2L4S A;  2UZC A;  3DIW A;  3GDU A;  1NF3 C;  1W9O A;  1L6O A;  1Y7N A;  2DMZ A;  2KL1 A;  5HFB A;  2JSN A;  2REY A;  3RLE A;  3K50 A;  3E17 A;  2V1W A;  2CSS A;  1RZX A;  2RRM A;  3B76 A;  2Q9V A;  3ID4 A;  4NNL A;  5E1Y A;  3SUZ A;  2EDZ A;  2OCS A;  5HDY A;  5D13 A;  1I92 A;  2EEI A;  2K1Z A;  4K75 A;  2OPG A;  2ZPL A;  2KJK A;  2QBW A;  2KOM A;  3KZE A;  4WYT A;  1V1T A;  3NGH A;  3DJA A;  5HFD A;  2KBS A;  2RCZ A;  1KWA A;  1UEW A;  5E11 A;  3BPU A;  1QAV B;  1Y8T A;  1MC7 A;  4KFV A;  1FC7 A;  4JJ0 A;  2AWU A;  4H11 A;  1MFL A;  1TP5 A;  2H2B A;  2YUY A;  2QG1 A;  4JL7 A;  3GCO A;  3LNX A;  5F67 A;  4NMS A;  3O46 A;  3R0H A;  2FNE A;  2M0V A;  2IWP A;  1I16 A;  3TSW A;  2V90 A;  1WFG A;  1X6D A;  1LCY A;  4Z33 A;  5HFE A;  4MPA A;  1IU0 A;  1X9Z A;  2DLS A;  5I7Z A;  1VB7 A;  2DB5 A;  1K32 A;  3QE1 A;  2L97 A;  1VAE A;  1VJ6 A;  3QGL A;  2W7R A;  2KG2 A;  1UIT A;  2EGK A;  2VSP A;  4XHV A;  2I0I A;  2M10 A;  2VWR A;  1G9O A;  2JXO A;  4HOP B;  5HFC A;  4JOF A;  5E21 A;  1V5Q A;  4EDJ A;  2OS6 A;  4JOE A;  1WI4 A;  1N6F A;  2KPK A;  1UHP A;  1P1E A;  1WG6 A;  2KQF A;  2JIN A;  2OSG A;  1B8Q A;  5DTH A;  4GHN A;  4JOJ A;  1Q3O A;  2OZF A;  5EZ0 A;  3MH6 A;  2KOH A;  3R69 A;  1QLC A;  2KJD A;  2I0L A;  3HPK A;  3RL7 A;  4E35 A;  1OZI A;  4NXP A;  5FHT A;  2HGA A;  4LMM A;  1WIF A;  3STJ A;  2LA8 A;  2GEF A;  2YT8 A;  3GAB A;  4NMO A;  2OMJ A;  2D8I A;  3GJ9 A;  2EV8 A;  4FGM A;  1RY4 A;  3O5N A;  1WHA A;  2VZ5 A;  5EYZ A;  1TP3 A;  4F8K A;  2H3L A;  1NTE A;  4JOR A;  1FCF A;  1GQ4 A;  4E3B A;  2LC6 A;  1Z87 A;  2AWX A;  1U37 A;  1N6E A;  3KHF A;  2AWW A;  3CBZ A;  2I1N A;  2JIL A;  1ZOK A;  4OEO A;  1Z86 A;  3L4F D;  1UM1 A;  1UJV A;  2O2T A;  2EJY A;  1WHD A;  2LC7 A;  1SOT A;  1SOZ A;  4O06 A;  2IWQ A;  1BFE A;  1W9E A;  3GDV A;  1WF7 A;  5HF4 A;  2EAQ A;  1FC9 A;  3TSV A;  2JWE A;  3MH7 A;  2I04 A;  3TMH A;  5E6P B;  3NFK A;  3HVQ C;  1D5G A;  4K78 A;  2AIN A;  2PKT A;  5HEB A;  3PV5 A;  1Q3P A;  2KAW A;  1TQ3 A;  4N6X A;  5HFF A;  5HJ1 A;  1U3B A;  4YDP A;  2FCF A;  1UEZ A;  2EHR A;  4Q6S A;  4JOG A;  2Z17 A;  3KDK A;  4Q2Q A;  2W4F A;  2H3M A;  3DOR A;  2M0Z A;  5IL9 A;  4Q6H A;  1IU2 A;  2G2L A;  2QKT A;  4NNM A;  2YTW A;  2EGO A;  1M5Z A;  4NMT A;  4KFW A;  2R4H A;  3NFL A;  5E22 A;  3CC0 A;  2QKV A;  4NXR A;  3WKM A;  2D90 A;  2MHO A;  3PDV A;  3NCV A;  1V5L A;  3GSL A;  4JJ3 A;  1X8S A;  1Q7X A;  3SHU A;  2EEJ A;  2OQS A;  1R6J A;  1V6B A;  1X5R A;  2KA9 A;  3CBX A;  3K1R A;  5HED A;  3QO6 A;  3ID1 A;  3ZRT A;  3I1E A;  1UEP A;  2KJP A;  3KZD A;  4Q2P A;  1WH1 A;  1U38 A;  3SOE A;  3K82 A;  2JIK A;  3ID3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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