3CYYA

The crystal structure of zo-1 pdz2 in complex with the cx43 peptide
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
80
structure length
80
Chain Sequence
KPTKVTLVKSAKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
pubmed doi rcsb
molecule keywords Tight junction protein ZO-1
molecule tags Peptide binding protein
source organism Homo sapiens
total genus 15
structure length 80
sequence length 80
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 3cyyA01
2PKUA 4Q6SA 2VWRA 3R69A 1V1TA 3CH8A 1OZIA 1U38A 4F8KA 1V5LA 5FB8C 4JOKA 2QBWA 4NMPA 3K82A 4IC6A 2KA9A 3CBZA 1IHJA 1OBYA 3FY5A 1IU0A 1W9OA 4NMTA 1VA8A 1FC6A 2LOBA 4FGMA 2M0VA 1N6FA 2HE2A 4UU5A 5E11A 2REYA 1Y7NA 4REYA 2KG2A 4K78A 2VPHA 1WIFA 2KQFA 4E34A 2M0UA 2I0LA 1UFXA 1Q3OA 2PDZA 3I1EA 5HF4A 2OSGA 1PDRA 1WI2A 3BPUA 4OEPA 2AWWA 5B6LA 2JWEA 2QG1A 1WF8A 1GM1A 2D90A 1QLCA 2ENOA 5D13A 2KAWA 1WJLA 2EV8A 4Q2NA 2M3MA 3ID2A 1X5NA 2JINA 4NMQA 1WFGA 4K75A 4R2ZA 2YTWA 1U37A 4L8NA 4AMHA 3DJ3A 1UM7A 2Z9IA 3SFJA 2DLSA 1BFEA 3O46A 1WG6A 1G9OA 1VAEA 2YUBA 2YT7A 3JXTA 2H3LA 2KPKA 5JXBA 5HFDA 1SOZA 1WF7A 5HEDA 4Q2PA 3ID4A 1P1DA 3K1RA 3ZRTA 3DJAA 3GDSA 4NMOA 4NNMA 2OMJA 2VZ5A 4NMRA 4OAJA 2QKUA 1UM1A 2JXOA 2LA8A 2M0TA 1V62A 3ID1A 2JIKA 5F3XA 1N6DA 1Q3PA 3HPMA 1WH1A 1UJUA 4EDJA 1TP5A 1RZXA 1QAVB 5E21A 2DM8A 5E1YA 1GQ5A 2H3MA 3CC0A 4Z8JA 3B76A 4MPAA 4NXRA 5E22A 2UZCA 2JREA 4E35A 1UEZA 4K6YA 1TE0A 4GHNA 2PKTA 2DJTA 4GVDA 2IWPA 1K32A 2PA1A 2W7RA 1IU2A 2DLUA 1UF1A 5DTHA 2IWQA 1MFLA 2OZFA 2CSSA 3TSWA 3I4WA 4HOPB 2DB5A 4OEOA 3SHUA 2EGNA 2EGKA 3MH4A 1Q7XA 4XHVA 3PDZA 2G2LA 2VSVA 4NXPA 4WYTA 5GLJA 2EHRA 1M5ZA 3QDOA 3PS4A 4E3BA 2LUIA 2EEHA 2V1WA 1ZOKA 3O5NA 2AINA 2D92A 5HEYA 1GQ4A 2X7ZA 4JOHA 1TQ3A 4PQWA 3VQFA 3SHWA 3QIKA 5EYZA 1I92A 4K76A 3E17A 1VB7A 3R68A 4NXQA 2FNEA 3CBYA 4P0CA 1KEFA 1FC7A 4P2AB 1L6OA 2MX6A 1X5RA 5F67A 4UU6A 1P1EA 1VCWA 2WL7A 2KOHA 3PDVA 2KJDA 2I0IA 1I16A 3L4FD 1KY9A 2EDPA 2KYLA 3DIWA 3GDUA 4LMMA 5I7ZA 5A2PA 1X8SA 2I4SA 2F5YA 4RI0A 2KPLA 2G5MB 1RGWA 2YT8A 4Q2QA 2AWUA 2QT5A 4NMSA 2FN5A 5HEBA 2KV8A 1WHDA 2IWOA 3MH7A 2I04A 5HETA 2HGAA 3KHFA 2E7KA 2QKTA 1UEWA 3HVQC 2GZVA 5E6PB 3EGGC 2AWXA 3QGLA 3PV5A 1YBOA 3GSLA 5FHTA 2DAZA 3OU0A 1XZ9A 2M0ZA 1OBZA 1R6JA 1B8QA 2R3YA 2EEGA 3QJMA 3CYYA 3KZEA 4Q2OA 1WFVA 2KRGA 3GCOA 2IWNA 3CBXA 4G69A 2R4HA 2PNTA 2H2BA 1UEQA 3SUZA 2Q3GA 1N7EA 3KZDA 3TSVA 1QAUA 1N99A 3GGEA 4JL7A 1OBXA 3R0HA 3AXAA 2RRMA 3I18A 2ZPMA 1LCYA 1TP3A 1WHAA 1UHPA 2KJKA 1W9QA 2JOAA 1X45A 3WKLA 4JOJA 2JILA 5HFEA 2EXGA 2OS6A 4YDPA 3NFKA 2ZPLA 2I6VA 2L97A 2EDZA 3WKMA 5HFFA 4Q6HA 2K20A 1KWAA 3RL7A 4JOFA 2KL1A 5HFCA 3OTPA 4YYXA 3CS0A 2O2TA 1RY4A 3QE1A 2Z17A 1BE9A 3PV4A 2EGOA 4Q3HA 4O06A 1ZUBA 1NF3C 2LC6A 2EJYA 2YUYA 4GVCA 1NTEA 4NMVA 1UJDA 4WYUA 1V6BA 1WI4A 2CSJA 2D8IA 5HJ1A 3GDVA 2OCSA 2CS5A 2PZDA 5G1DA 3GCNA 2DMZA 2EAQA 2P3WA 3NFLA 2LC7A 2OGPA 1UJVA 1MFGA 1UITA 1QAVA 5GNDA 5HFBA 2H2CA 3VQGA 2KOJA 3DJ1A 2KOMA 2FCFA 5H3JA 1U3BA 3QJNA 1VJ6A 2M10A 5HF1A 2V90A 4JOPA 2FE5A 5HDYA 2OPGA 1FC9A 2HE4A 2KJPA 2QKVA 1FCFA 3TMHA 1U39A 3K50A 2RCZA 3LNYA 3DORA 2EEJA 2W4FA 3RL8A 2EDVA 1SOTA 2VSPA 4KFVA 2KBSA 1X6DA 2I1NA 3GJ9A 2DC2A 4HOPA 3PV2A 3TSZA 4K72A 2MHOA 3SOEA 1MC7A 2BYGA 2Q9VA 1UEPA 4N6XA 1Z87A 4NNLA 1N7FA 1W9EA 2L4TA 3MH6A 2F0AA 1X5QA 2VRFA 1Y8TA 3NGHA 3LNXA 1T2MA 3RLEA 4JOGA 3HPKA 1Z86A 5G1EA 5EZ0A 3STJA 2EEIA 1D5GA 1RGRA 3ID3A 4KFWA 1V5QA 1N7TA 4JORA 4H11A 2OQSA 2K1ZA 3QO6A 4JOEA 4Z33A 2L4SA 3EGHC 2DKRA 1N6EA
chains in the Genus database with same CATH superfamily
2PKUA 4Q6SA 2VWRA 3R69A 1V1TA 3CH8A 2GEFA 1OZIA 1U38A 4F8KA 1V5LA 5FB8C 4JOKA 5ILBA 2QBWA 4NMPA 3K82A 4IC6A 2KA9A 3CBZA 1IHJA 1OBYA 3FY5A 1IU0A 1W9OA 4NMTA 1VA8A 1FC6A 2LOBA 4FGMA 2M0VA 1N6FA 2HE2A 4UU5A 5E11A 2REYA 1Y7NA 4REYA 2KG2A 4K78A 2VPHA 1WIFA 2KQFA 4E34A 2M0UA 2I0LA 1UFXA 1Q3OA 2PDZA 3I1EA 5HF4A 2OSGA 1PDRA 1WI2A 3BPUA 4OEPA 2AWWA 5B6LA 2JWEA 2QG1A 1WF8A 1GM1A 2D90A 1QLCA 2ENOA 5D13A 2KAWA 1WJLA 2EV8A 4Q2NA 2M3MA 3ID2A 1X5NA 2JINA 4NMQA 1WFGA 4K75A 4R2ZA 2YTWA 1U37A 4L8NA 4AMHA 3DJ3A 1UM7A 2Z9IA 3SFJA 2DLSA 1BFEA 3O46A 1WG6A 1G9OA 1VAEA 2YUBA 2YT7A 3JXTA 2H3LA 2KPKA 5JXBA 5HFDA 1SOZA 1WF7A 5HEDA 4Q2PA 3ID4A 1P1DA 3K1RA 3ZRTA 3DJAA 3GDSA 4NMOA 4NNMA 2OMJA 2VZ5A 4NMRA 4OAJA 2QKUA 1UM1A 2JXOA 2LA8A 5IL9A 2M0TA 1V62A 3ID1A 2JIKA 5F3XA 1N6DA 1Q3PA 3HPMA 1WH1A 1UJUA 4EDJA 1TP5A 1RZXA 1QAVB 5E21A 2DM8A 5E1YA 1GQ5A 2H3MA 3CC0A 4Z8JA 3B76A 4MPAA 4NXRA 5E22A 2UZCA 2JREA 4E35A 1UEZA 4K6YA 1TE0A 4GHNA 2PKTA 2DJTA 4GVDA 2IWPA 1K32A 2PA1A 2W7RA 1IU2A 3NCVA 2DLUA 1UF1A 5DTHA 2IWQA 1MFLA 2OZFA 2CSSA 3TSWA 3I4WA 4HOPB 2DB5A 4OEOA 3SHUA 2EGNA 2EGKA 3MH4A 1Q7XA 4XHVA 3PDZA 2G2LA 2VSVA 4NXPA 4WYTA 5GLJA 2EHRA 1M5ZA 3QDOA 3PS4A 4E3BA 2LUIA 2EEHA 2V1WA 1ZOKA 3O5NA 2AINA 2D92A 5HEYA 1GQ4A 2X7ZA 4JOHA 1TQ3A 4PQWA 3VQFA 3SHWA 3QIKA 5EYZA 1I92A 4K76A 3E17A 1VB7A 3R68A 4NXQA 4JJ3A 2FNEA 3CBYA 4P0CA 1KEFA 1FC7A 4P2AB 1L6OA 2MX6A 1X5RA 5F67A 4UU6A 1P1EA 1VCWA 2WL7A 2KOHA 3PDVA 2KJDA 2I0IA 1I16A 3L4FD 1KY9A 2EDPA 2KYLA 3DIWA 3GDUA 4LMMA 5I7ZA 5A2PA 1X8SA 2I4SA 2F5YA 5B42A 4RI0A 2KPLA 2G5MB 1RGWA 2YT8A 4Q2QA 2AWUA 2QT5A 4NMSA 2FN5A 5HEBA 2KV8A 1WHDA 2IWOA 3MH7A 2I04A 5HETA 2HGAA 3KHFA 2E7KA 2QKTA 1UEWA 3HVQC 2GZVA 5E6PB 3EGGC 2AWXA 3QGLA 3PV5A 1YBOA 3GSLA 5FHTA 2DAZA 3OU0A 1XZ9A 2M0ZA 1OBZA 1R6JA 1B8QA 2R3YA 2EEGA 3QJMA 3CYYA 3KZEA 4Q2OA 1WFVA 2KRGA 3GCOA 2IWNA 3CBXA 4G69A 2R4HA 2PNTA 2H2BA 1UEQA 3SUZA 2Q3GA 1N7EA 3KZDA 3TSVA 1QAUA 1N99A 3GGEA 4JL7A 1OBXA 3R0HA 3AXAA 2RRMA 3I18A 2ZPMA 1LCYA 1TP3A 1WHAA 1UHPA 2KJKA 1W9QA 2JOAA 1X45A 3WKLA 4JOJA 2JILA 5HFEA 3KDKA 2EXGA 2OS6A 4YDPA 3NFKA 2ZPLA 2I6VA 2L97A 2EDZA 3WKMA 5HFFA 4Q6HA 2K20A 1KWAA 3RL7A 4JOFA 2KL1A 5HFCA 3OTPA 4YYXA 2JSNA 3CS0A 2O2TA 1RY4A 3QE1A 2Z17A 1BE9A 3PV4A 2EGOA 4Q3HA 4O06A 1ZUBA 3KDGA 1NF3C 2LC6A 2EJYA 2YUYA 4GVCA 1NTEA 4NMVA 1UJDA 4WYUA 1V6BA 1WI4A 2CSJA 2D8IA 5HJ1A 3GDVA 2OCSA 2CS5A 2PZDA 5G1DA 3GCNA 2DMZA 2EAQA 4FLNA 2P3WA 3NFLA 2LC7A 2OGPA 1UJVA 1MFGA 1UITA 1QAVA 5GNDA 5HFBA 2H2CA 3VQGA 2KOJA 3DJ1A 2KOMA 2FCFA 5H3JA 1U3BA 3QJNA 1VJ6A 2M10A 5HF1A 2V90A 4JOPA 2FE5A 5HDYA 2OPGA 1FC9A 2HE4A 2KJPA 2QKVA 1FCFA 3TMHA 1U39A 3K50A 2RCZA 3LNYA 1X9ZA 3DORA 2EEJA 2W4FA 3RL8A 2EDVA 1SOTA 2VSPA 4KFVA 2KBSA 1X6DA 4JJ0A 2I1NA 3GJ9A 2DC2A 4HOPA 3PV2A 3TSZA 4K72A 2MHOA 3SOEA 1MC7A 2BYGA 2Q9VA 1UEPA 4N6XA 1Z87A 4NNLA 1N7FA 1W9EA 2L4TA 3MH6A 2F0AA 1X5QA 2VRFA 1Y8TA 3NGHA 3LNXA 1T2MA 3RLEA 4JOGA 3HPKA 1Z86A 5G1EA 3GABA 5EZ0A 3STJA 2EEIA 1D5GA 1RGRA 3ID3A 4KFWA 1V5QA 1N7TA 4JORA 4H11A 2OQSA 2K1ZA 3QO6A 4JOEA 4Z33A 2L4SA 3EGHC 2DKRA 1N6EA
chains in the Genus database with same CATH topology
2PKUA 4Q6SA 2VWRA 3R69A 1V1TA 3CH8A 2GEFA 1OZIA 1U38A 4F8KA 1V5LA 5FB8C 4JOKA 5ILBA 2QBWA 4NMPA 3K82A 4IC6A 2KA9A 3CBZA 1IHJA 1OBYA 3FY5A 1IU0A 1W9OA 4NMTA 1VA8A 1FC6A 2LOBA 4FGMA 2M0VA 1N6FA 2HE2A 4UU5A 5E11A 2REYA 1Y7NA 4REYA 2KG2A 4K78A 2VPHA 1WIFA 2KQFA 4E34A 2M0UA 2I0LA 1UFXA 1Q3OA 2PDZA 3I1EA 5HF4A 2OSGA 1PDRA 1WI2A 3BPUA 4OEPA 2AWWA 5B6LA 2JWEA 2QG1A 1WF8A 1GM1A 2D90A 1QLCA 2ENOA 5D13A 2KAWA 1WJLA 2EV8A 4Q2NA 2M3MA 3ID2A 1X5NA 2JINA 4NMQA 1WFGA 4K75A 4R2ZA 2YTWA 1U37A 4L8NA 4AMHA 3DJ3A 1UM7A 2Z9IA 3SFJA 2DLSA 1BFEA 3O46A 1WG6A 1G9OA 1VAEA 2YUBA 2YT7A 3JXTA 2H3LA 2KPKA 5JXBA 5HFDA 1SOZA 1WF7A 5HEDA 4Q2PA 3ID4A 1P1DA 3K1RA 3ZRTA 3DJAA 3GDSA 4NMOA 4NNMA 2OMJA 2VZ5A 4NMRA 4OAJA 2QKUA 1UM1A 2JXOA 2LA8A 5IL9A 2M0TA 1V62A 3ID1A 2JIKA 5F3XA 1N6DA 1Q3PA 3HPMA 1WH1A 1UJUA 4EDJA 1TP5A 1RZXA 1QAVB 5E21A 2DM8A 5E1YA 1GQ5A 2H3MA 3CC0A 4Z8JA 3B76A 4MPAA 4NXRA 5E22A 2UZCA 2JREA 4E35A 1UEZA 4K6YA 1TE0A 4GHNA 2PKTA 2DJTA 4GVDA 2IWPA 1K32A 2PA1A 2W7RA 1IU2A 3NCVA 2DLUA 1UF1A 5DTHA 2IWQA 1MFLA 2OZFA 2CSSA 3TSWA 3I4WA 4HOPB 2DB5A 4OEOA 3SHUA 2EGNA 2EGKA 3MH4A 1Q7XA 4XHVA 3PDZA 2G2LA 2VSVA 4NXPA 4WYTA 5GLJA 2EHRA 1M5ZA 3QDOA 3PS4A 4E3BA 2LUIA 2EEHA 2V1WA 1ZOKA 3O5NA 2AINA 2D92A 5HEYA 1GQ4A 2X7ZA 4JOHA 1TQ3A 4PQWA 3VQFA 3SHWA 3QIKA 5EYZA 1I92A 4K76A 3E17A 1VB7A 3R68A 4NXQA 4JJ3A 2FNEA 3CBYA 4P0CA 1KEFA 1FC7A 4P2AB 1L6OA 2MX6A 1X5RA 5F67A 4UU6A 1P1EA 1VCWA 2WL7A 2KOHA 3PDVA 2KJDA 2I0IA 1I16A 3L4FD 1KY9A 2EDPA 2KYLA 3DIWA 3GDUA 4LMMA 5I7ZA 5A2PA 1X8SA 2I4SA 2F5YA 5B42A 4RI0A 2KPLA 2G5MB 1RGWA 2YT8A 4Q2QA 2AWUA 2QT5A 4NMSA 2FN5A 5HEBA 2KV8A 1WHDA 2IWOA 3MH7A 2I04A 5HETA 2HGAA 3KHFA 2E7KA 2QKTA 1UEWA 3HVQC 2GZVA 5E6PB 3EGGC 2AWXA 3QGLA 3PV5A 1YBOA 3GSLA 5FHTA 2DAZA 3OU0A 1XZ9A 2M0ZA 1OBZA 1R6JA 1B8QA 2R3YA 2EEGA 3QJMA 3CYYA 3KZEA 4Q2OA 1WFVA 2KRGA 3GCOA 2IWNA 3CBXA 4G69A 2R4HA 2PNTA 2H2BA 1UEQA 3SUZA 2Q3GA 1N7EA 3KZDA 3TSVA 1QAUA 1N99A 3GGEA 4JL7A 1OBXA 3R0HA 3AXAA 2RRMA 3I18A 2ZPMA 1LCYA 1TP3A 1WHAA 1UHPA 2KJKA 1W9QA 2JOAA 1X45A 3WKLA 4JOJA 2JILA 5HFEA 3KDKA 2EXGA 2OS6A 4YDPA 3NFKA 2ZPLA 2I6VA 2L97A 2EDZA 3WKMA 5HFFA 4Q6HA 2K20A 1KWAA 3RL7A 4JOFA 2KL1A 5HFCA 3OTPA 4YYXA 2JSNA 3CS0A 2O2TA 1RY4A 3QE1A 2Z17A 1BE9A 3PV4A 2EGOA 4Q3HA 4O06A 1ZUBA 3KDGA 1NF3C 2LC6A 2EJYA 2YUYA 4GVCA 1NTEA 4NMVA 1UJDA 4WYUA 1V6BA 1WI4A 2CSJA 2D8IA 5HJ1A 3GDVA 2OCSA 2CS5A 2PZDA 5G1DA 3GCNA 2DMZA 2EAQA 4FLNA 2P3WA 3NFLA 2LC7A 2OGPA 1UJVA 1MFGA 1UITA 1QAVA 5GNDA 5HFBA 2H2CA 3VQGA 2KOJA 3DJ1A 2KOMA 2FCFA 5H3JA 1U3BA 3QJNA 1VJ6A 2M10A 5HF1A 2V90A 4JOPA 2FE5A 5HDYA 2OPGA 1FC9A 2HE4A 2KJPA 2QKVA 1FCFA 3TMHA 1U39A 3K50A 2RCZA 3LNYA 1X9ZA 3DORA 2EEJA 2W4FA 3RL8A 2EDVA 1SOTA 2VSPA 4KFVA 2KBSA 1X6DA 4JJ0A 2I1NA 3GJ9A 2DC2A 4HOPA 3PV2A 3TSZA 4K72A 2MHOA 3SOEA 1MC7A 2BYGA 2Q9VA 1UEPA 4N6XA 1Z87A 4NNLA 1N7FA 1W9EA 2L4TA 3MH6A 2F0AA 1X5QA 2VRFA 1Y8TA 3NGHA 3LNXA 1T2MA 3RLEA 4JOGA 3HPKA 1Z86A 5G1EA 3GABA 5EZ0A 3STJA 2EEIA 1D5GA 1RGRA 3ID3A 4KFWA 1V5QA 1N7TA 4JORA 4H11A 2OQSA 2K1ZA 3QO6A 4JOEA 4Z33A 2L4SA 3EGHC 2DKRA 1N6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PKU A;  4Q6S A;  2VWR A;  3R69 A;  1V1T A;  3CH8 A;  1OZI A;  1U38 A;  4F8K A;  1V5L A;  5FB8 C;  4JOK A;  2QBW A;  4NMP A;  3K82 A;  4IC6 A;  2KA9 A;  3CBZ A;  1IHJ A;  1OBY A;  3FY5 A;  1IU0 A;  1W9O A;  4NMT A;  1VA8 A;  1FC6 A;  2LOB A;  4FGM A;  2M0V A;  1N6F A;  2HE2 A;  4UU5 A;  5E11 A;  2REY A;  1Y7N A;  4REY A;  2KG2 A;  4K78 A;  2VPH A;  1WIF A;  2KQF A;  4E34 A;  2M0U A;  2I0L A;  1UFX A;  1Q3O A;  2PDZ A;  3I1E A;  5HF4 A;  2OSG A;  1PDR A;  1WI2 A;  3BPU A;  4OEP A;  2AWW A;  5B6L A;  2JWE A;  2QG1 A;  1WF8 A;  1GM1 A;  2D90 A;  1QLC A;  2ENO A;  5D13 A;  2KAW A;  1WJL A;  2EV8 A;  4Q2N A;  2M3M A;  3ID2 A;  1X5N A;  2JIN A;  4NMQ A;  1WFG A;  4K75 A;  4R2Z A;  2YTW A;  1U37 A;  4L8N A;  4AMH A;  3DJ3 A;  1UM7 A;  2Z9I A;  3SFJ A;  2DLS A;  1BFE A;  3O46 A;  1WG6 A;  1G9O A;  1VAE A;  2YUB A;  2YT7 A;  3JXT A;  2H3L A;  2KPK A;  5JXB A;  5HFD A;  1SOZ A;  1WF7 A;  5HED A;  4Q2P A;  3ID4 A;  1P1D A;  3K1R A;  3ZRT A;  3DJA A;  3GDS A;  4NMO A;  4NNM A;  2OMJ A;  2VZ5 A;  4NMR A;  4OAJ A;  2QKU A;  1UM1 A;  2JXO A;  2LA8 A;  2M0T A;  1V62 A;  3ID1 A;  2JIK A;  5F3X A;  1N6D A;  1Q3P A;  3HPM A;  1WH1 A;  1UJU A;  4EDJ A;  1TP5 A;  1RZX A;  1QAV B;  5E21 A;  2DM8 A;  5E1Y A;  1GQ5 A;  2H3M A;  3CC0 A;  4Z8J A;  3B76 A;  4MPA A;  4NXR A;  5E22 A;  2UZC A;  2JRE A;  4E35 A;  1UEZ A;  4K6Y A;  1TE0 A;  4GHN A;  2PKT A;  2DJT A;  4GVD A;  2IWP A;  1K32 A;  2PA1 A;  2W7R A;  1IU2 A;  2DLU A;  1UF1 A;  5DTH A;  2IWQ A;  1MFL A;  2OZF A;  2CSS A;  3TSW A;  3I4W A;  4HOP B;  2DB5 A;  4OEO A;  3SHU A;  2EGN A;  2EGK A;  3MH4 A;  1Q7X A;  4XHV A;  3PDZ A;  2G2L A;  2VSV A;  4NXP A;  4WYT A;  5GLJ A;  2EHR A;  1M5Z A;  3QDO A;  3PS4 A;  4E3B A;  2LUI A;  2EEH A;  2V1W A;  1ZOK A;  3O5N A;  2AIN A;  2D92 A;  5HEY A;  1GQ4 A;  2X7Z A;  4JOH A;  1TQ3 A;  4PQW A;  3VQF A;  3SHW A;  3QIK A;  5EYZ A;  1I92 A;  4K76 A;  3E17 A;  1VB7 A;  3R68 A;  4NXQ A;  2FNE A;  3CBY A;  4P0C A;  1KEF A;  1FC7 A;  4P2A B;  1L6O A;  2MX6 A;  1X5R A;  5F67 A;  4UU6 A;  1P1E A;  1VCW A;  2WL7 A;  2KOH A;  3PDV A;  2KJD A;  2I0I A;  1I16 A;  3L4F D;  1KY9 A;  2EDP A;  2KYL A;  3DIW A;  3GDU A;  4LMM A;  5I7Z A;  5A2P A;  1X8S A;  2I4S A;  2F5Y A;  4RI0 A;  2KPL A;  2G5M B;  1RGW A;  2YT8 A;  4Q2Q A;  2AWU A;  2QT5 A;  4NMS A;  2FN5 A;  5HEB A;  2KV8 A;  1WHD A;  2IWO A;  3MH7 A;  2I04 A;  5HET A;  2HGA A;  3KHF A;  2E7K A;  2QKT A;  1UEW A;  3HVQ C;  2GZV A;  5E6P B;  3EGG C;  2AWX A;  3QGL A;  3PV5 A;  1YBO A;  3GSL A;  5FHT A;  2DAZ A;  3OU0 A;  1XZ9 A;  2M0Z A;  1OBZ A;  1R6J A;  1B8Q A;  2R3Y A;  2EEG A;  3QJM A;  3CYY A;  3KZE A;  4Q2O A;  1WFV A;  2KRG A;  3GCO A;  2IWN A;  3CBX A;  4G69 A;  2R4H A;  2PNT A;  2H2B A;  1UEQ A;  3SUZ A;  2Q3G A;  1N7E A;  3KZD A;  3TSV A;  1QAU A;  1N99 A;  3GGE A;  4JL7 A;  1OBX A;  3R0H A;  3AXA A;  2RRM A;  3I18 A;  2ZPM A;  1LCY A;  1TP3 A;  1WHA A;  1UHP A;  2KJK A;  1W9Q A;  2JOA A;  1X45 A;  3WKL A;  4JOJ A;  2JIL A;  5HFE A;  2EXG A;  2OS6 A;  4YDP A;  3NFK A;  2ZPL A;  2I6V A;  2L97 A;  2EDZ A;  3WKM A;  5HFF A;  4Q6H A;  2K20 A;  1KWA A;  3RL7 A;  4JOF A;  2KL1 A;  5HFC A;  3OTP A;  4YYX A;  3CS0 A;  2O2T A;  1RY4 A;  3QE1 A;  2Z17 A;  1BE9 A;  3PV4 A;  2EGO A;  4Q3H A;  4O06 A;  1ZUB A;  1NF3 C;  2LC6 A;  2EJY A;  2YUY A;  4GVC A;  1NTE A;  4NMV A;  1UJD A;  4WYU A;  1V6B A;  1WI4 A;  2CSJ A;  2D8I A;  5HJ1 A;  3GDV A;  2OCS A;  2CS5 A;  2PZD A;  5G1D A;  3GCN A;  2DMZ A;  2EAQ A;  2P3W A;  3NFL A;  2LC7 A;  2OGP A;  1UJV A;  1MFG A;  1UIT A;  1QAV A;  5GND A;  5HFB A;  2H2C A;  3VQG A;  2KOJ A;  3DJ1 A;  2KOM A;  2FCF A;  5H3J A;  1U3B A;  3QJN A;  1VJ6 A;  2M10 A;  5HF1 A;  2V90 A;  4JOP A;  2FE5 A;  5HDY A;  2OPG A;  1FC9 A;  2HE4 A;  2KJP A;  2QKV A;  1FCF A;  3TMH A;  1U39 A;  3K50 A;  2RCZ A;  3LNY A;  3DOR A;  2EEJ A;  2W4F A;  3RL8 A;  2EDV A;  1SOT A;  2VSP A;  4KFV A;  2KBS A;  1X6D A;  2I1N A;  3GJ9 A;  2DC2 A;  4HOP A;  3PV2 A;  3TSZ A;  4K72 A;  2MHO A;  3SOE A;  1MC7 A;  2BYG A;  2Q9V A;  1UEP A;  4N6X A;  1Z87 A;  4NNL A;  1N7F A;  1W9E A;  2L4T A;  3MH6 A;  2F0A A;  1X5Q A;  2VRF A;  1Y8T A;  3NGH A;  3LNX A;  1T2M A;  3RLE A;  4JOG A;  3HPK A;  1Z86 A;  5G1E A;  5EZ0 A;  3STJ A;  2EEI A;  1D5G A;  1RGR A;  3ID3 A;  4KFW A;  1V5Q A;  1N7T A;  4JOR A;  4H11 A;  2OQS A;  2K1Z A;  3QO6 A;  4JOE A;  4Z33 A;  2L4S A;  3EGH C;  2DKR A;  1N6E A; 
#chains in the Genus database with same CATH topology
 2PKU A;  4Q6S A;  2VWR A;  3R69 A;  1V1T A;  3CH8 A;  2GEF A;  1OZI A;  1U38 A;  4F8K A;  1V5L A;  5FB8 C;  4JOK A;  5ILB A;  2QBW A;  4NMP A;  3K82 A;  4IC6 A;  2KA9 A;  3CBZ A;  1IHJ A;  1OBY A;  3FY5 A;  1IU0 A;  1W9O A;  4NMT A;  1VA8 A;  1FC6 A;  2LOB A;  4FGM A;  2M0V A;  1N6F A;  2HE2 A;  4UU5 A;  5E11 A;  2REY A;  1Y7N A;  4REY A;  2KG2 A;  4K78 A;  2VPH A;  1WIF A;  2KQF A;  4E34 A;  2M0U A;  2I0L A;  1UFX A;  1Q3O A;  2PDZ A;  3I1E A;  5HF4 A;  2OSG A;  1PDR A;  1WI2 A;  3BPU A;  4OEP A;  2AWW A;  5B6L A;  2JWE A;  2QG1 A;  1WF8 A;  1GM1 A;  2D90 A;  1QLC A;  2ENO A;  5D13 A;  2KAW A;  1WJL A;  2EV8 A;  4Q2N A;  2M3M A;  3ID2 A;  1X5N A;  2JIN A;  4NMQ A;  1WFG A;  4K75 A;  4R2Z A;  2YTW A;  1U37 A;  4L8N A;  4AMH A;  3DJ3 A;  1UM7 A;  2Z9I A;  3SFJ A;  2DLS A;  1BFE A;  3O46 A;  1WG6 A;  1G9O A;  1VAE A;  2YUB A;  2YT7 A;  3JXT A;  2H3L A;  2KPK A;  5JXB A;  5HFD A;  1SOZ A;  1WF7 A;  5HED A;  4Q2P A;  3ID4 A;  1P1D A;  3K1R A;  3ZRT A;  3DJA A;  3GDS A;  4NMO A;  4NNM A;  2OMJ A;  2VZ5 A;  4NMR A;  4OAJ A;  2QKU A;  1UM1 A;  2JXO A;  2LA8 A;  5IL9 A;  2M0T A;  1V62 A;  3ID1 A;  2JIK A;  5F3X A;  1N6D A;  1Q3P A;  3HPM A;  1WH1 A;  1UJU A;  4EDJ A;  1TP5 A;  1RZX A;  1QAV B;  5E21 A;  2DM8 A;  5E1Y A;  1GQ5 A;  2H3M A;  3CC0 A;  4Z8J A;  3B76 A;  4MPA A;  4NXR A;  5E22 A;  2UZC A;  2JRE A;  4E35 A;  1UEZ A;  4K6Y A;  1TE0 A;  4GHN A;  2PKT A;  2DJT A;  4GVD A;  2IWP A;  1K32 A;  2PA1 A;  2W7R A;  1IU2 A;  3NCV A;  2DLU A;  1UF1 A;  5DTH A;  2IWQ A;  1MFL A;  2OZF A;  2CSS A;  3TSW A;  3I4W A;  4HOP B;  2DB5 A;  4OEO A;  3SHU A;  2EGN A;  2EGK A;  3MH4 A;  1Q7X A;  4XHV A;  3PDZ A;  2G2L A;  2VSV A;  4NXP A;  4WYT A;  5GLJ A;  2EHR A;  1M5Z A;  3QDO A;  3PS4 A;  4E3B A;  2LUI A;  2EEH A;  2V1W A;  1ZOK A;  3O5N A;  2AIN A;  2D92 A;  5HEY A;  1GQ4 A;  2X7Z A;  4JOH A;  1TQ3 A;  4PQW A;  3VQF A;  3SHW A;  3QIK A;  5EYZ A;  1I92 A;  4K76 A;  3E17 A;  1VB7 A;  3R68 A;  4NXQ A;  4JJ3 A;  2FNE A;  3CBY A;  4P0C A;  1KEF A;  1FC7 A;  4P2A B;  1L6O A;  2MX6 A;  1X5R A;  5F67 A;  4UU6 A;  1P1E A;  1VCW A;  2WL7 A;  2KOH A;  3PDV A;  2KJD A;  2I0I A;  1I16 A;  3L4F D;  1KY9 A;  2EDP A;  2KYL A;  3DIW A;  3GDU A;  4LMM A;  5I7Z A;  5A2P A;  1X8S A;  2I4S A;  2F5Y A;  5B42 A;  4RI0 A;  2KPL A;  2G5M B;  1RGW A;  2YT8 A;  4Q2Q A;  2AWU A;  2QT5 A;  4NMS A;  2FN5 A;  5HEB A;  2KV8 A;  1WHD A;  2IWO A;  3MH7 A;  2I04 A;  5HET A;  2HGA A;  3KHF A;  2E7K A;  2QKT A;  1UEW A;  3HVQ C;  2GZV A;  5E6P B;  3EGG C;  2AWX A;  3QGL A;  3PV5 A;  1YBO A;  3GSL A;  5FHT A;  2DAZ A;  3OU0 A;  1XZ9 A;  2M0Z A;  1OBZ A;  1R6J A;  1B8Q A;  2R3Y A;  2EEG A;  3QJM A;  3CYY A;  3KZE A;  4Q2O A;  1WFV A;  2KRG A;  3GCO A;  2IWN A;  3CBX A;  4G69 A;  2R4H A;  2PNT A;  2H2B A;  1UEQ A;  3SUZ A;  2Q3G A;  1N7E A;  3KZD A;  3TSV A;  1QAU A;  1N99 A;  3GGE A;  4JL7 A;  1OBX A;  3R0H A;  3AXA A;  2RRM A;  3I18 A;  2ZPM A;  1LCY A;  1TP3 A;  1WHA A;  1UHP A;  2KJK A;  1W9Q A;  2JOA A;  1X45 A;  3WKL A;  4JOJ A;  2JIL A;  5HFE A;  3KDK A;  2EXG A;  2OS6 A;  4YDP A;  3NFK A;  2ZPL A;  2I6V A;  2L97 A;  2EDZ A;  3WKM A;  5HFF A;  4Q6H A;  2K20 A;  1KWA A;  3RL7 A;  4JOF A;  2KL1 A;  5HFC A;  3OTP A;  4YYX A;  2JSN A;  3CS0 A;  2O2T A;  1RY4 A;  3QE1 A;  2Z17 A;  1BE9 A;  3PV4 A;  2EGO A;  4Q3H A;  4O06 A;  1ZUB A;  3KDG A;  1NF3 C;  2LC6 A;  2EJY A;  2YUY A;  4GVC A;  1NTE A;  4NMV A;  1UJD A;  4WYU A;  1V6B A;  1WI4 A;  2CSJ A;  2D8I A;  5HJ1 A;  3GDV A;  2OCS A;  2CS5 A;  2PZD A;  5G1D A;  3GCN A;  2DMZ A;  2EAQ A;  4FLN A;  2P3W A;  3NFL A;  2LC7 A;  2OGP A;  1UJV A;  1MFG A;  1UIT A;  1QAV A;  5GND A;  5HFB A;  2H2C A;  3VQG A;  2KOJ A;  3DJ1 A;  2KOM A;  2FCF A;  5H3J A;  1U3B A;  3QJN A;  1VJ6 A;  2M10 A;  5HF1 A;  2V90 A;  4JOP A;  2FE5 A;  5HDY A;  2OPG A;  1FC9 A;  2HE4 A;  2KJP A;  2QKV A;  1FCF A;  3TMH A;  1U39 A;  3K50 A;  2RCZ A;  3LNY A;  1X9Z A;  3DOR A;  2EEJ A;  2W4F A;  3RL8 A;  2EDV A;  1SOT A;  2VSP A;  4KFV A;  2KBS A;  1X6D A;  4JJ0 A;  2I1N A;  3GJ9 A;  2DC2 A;  4HOP A;  3PV2 A;  3TSZ A;  4K72 A;  2MHO A;  3SOE A;  1MC7 A;  2BYG A;  2Q9V A;  1UEP A;  4N6X A;  1Z87 A;  4NNL A;  1N7F A;  1W9E A;  2L4T A;  3MH6 A;  2F0A A;  1X5Q A;  2VRF A;  1Y8T A;  3NGH A;  3LNX A;  1T2M A;  3RLE A;  4JOG A;  3HPK A;  1Z86 A;  5G1E A;  3GAB A;  5EZ0 A;  3STJ A;  2EEI A;  1D5G A;  1RGR A;  3ID3 A;  4KFW A;  1V5Q A;  1N7T A;  4JOR A;  4H11 A;  2OQS A;  2K1Z A;  3QO6 A;  4JOE A;  4Z33 A;  2L4S A;  3EGH C;  2DKR A;  1N6E A; 
#chains in the Genus database with same CATH homology
 2PKU A;  4Q6S A;  2VWR A;  3R69 A;  1V1T A;  3CH8 A;  2GEF A;  1OZI A;  1U38 A;  4F8K A;  1V5L A;  5FB8 C;  4JOK A;  5ILB A;  2QBW A;  4NMP A;  3K82 A;  4IC6 A;  2KA9 A;  3CBZ A;  1IHJ A;  1OBY A;  3FY5 A;  1IU0 A;  1W9O A;  4NMT A;  1VA8 A;  1FC6 A;  2LOB A;  4FGM A;  2M0V A;  1N6F A;  2HE2 A;  4UU5 A;  5E11 A;  2REY A;  1Y7N A;  4REY A;  2KG2 A;  4K78 A;  2VPH A;  1WIF A;  2KQF A;  4E34 A;  2M0U A;  2I0L A;  1UFX A;  1Q3O A;  2PDZ A;  3I1E A;  5HF4 A;  2OSG A;  1PDR A;  1WI2 A;  3BPU A;  4OEP A;  2AWW A;  5B6L A;  2JWE A;  2QG1 A;  1WF8 A;  1GM1 A;  2D90 A;  1QLC A;  2ENO A;  5D13 A;  2KAW A;  1WJL A;  2EV8 A;  4Q2N A;  2M3M A;  3ID2 A;  1X5N A;  2JIN A;  4NMQ A;  1WFG A;  4K75 A;  4R2Z A;  2YTW A;  1U37 A;  4L8N A;  4AMH A;  3DJ3 A;  1UM7 A;  2Z9I A;  3SFJ A;  2DLS A;  1BFE A;  3O46 A;  1WG6 A;  1G9O A;  1VAE A;  2YUB A;  2YT7 A;  3JXT A;  2H3L A;  2KPK A;  5JXB A;  5HFD A;  1SOZ A;  1WF7 A;  5HED A;  4Q2P A;  3ID4 A;  1P1D A;  3K1R A;  3ZRT A;  3DJA A;  3GDS A;  4NMO A;  4NNM A;  2OMJ A;  2VZ5 A;  4NMR A;  4OAJ A;  2QKU A;  1UM1 A;  2JXO A;  2LA8 A;  5IL9 A;  2M0T A;  1V62 A;  3ID1 A;  2JIK A;  5F3X A;  1N6D A;  1Q3P A;  3HPM A;  1WH1 A;  1UJU A;  4EDJ A;  1TP5 A;  1RZX A;  1QAV B;  5E21 A;  2DM8 A;  5E1Y A;  1GQ5 A;  2H3M A;  3CC0 A;  4Z8J A;  3B76 A;  4MPA A;  4NXR A;  5E22 A;  2UZC A;  2JRE A;  4E35 A;  1UEZ A;  4K6Y A;  1TE0 A;  4GHN A;  2PKT A;  2DJT A;  4GVD A;  2IWP A;  1K32 A;  2PA1 A;  2W7R A;  1IU2 A;  3NCV A;  2DLU A;  1UF1 A;  5DTH A;  2IWQ A;  1MFL A;  2OZF A;  2CSS A;  3TSW A;  3I4W A;  4HOP B;  2DB5 A;  4OEO A;  3SHU A;  2EGN A;  2EGK A;  3MH4 A;  1Q7X A;  4XHV A;  3PDZ A;  2G2L A;  2VSV A;  4NXP A;  4WYT A;  5GLJ A;  2EHR A;  1M5Z A;  3QDO A;  3PS4 A;  4E3B A;  2LUI A;  2EEH A;  2V1W A;  1ZOK A;  3O5N A;  2AIN A;  2D92 A;  5HEY A;  1GQ4 A;  2X7Z A;  4JOH A;  1TQ3 A;  4PQW A;  3VQF A;  3SHW A;  3QIK A;  5EYZ A;  1I92 A;  4K76 A;  3E17 A;  1VB7 A;  3R68 A;  4NXQ A;  4JJ3 A;  2FNE A;  3CBY A;  4P0C A;  1KEF A;  1FC7 A;  4P2A B;  1L6O A;  2MX6 A;  1X5R A;  5F67 A;  4UU6 A;  1P1E A;  1VCW A;  2WL7 A;  2KOH A;  3PDV A;  2KJD A;  2I0I A;  1I16 A;  3L4F D;  1KY9 A;  2EDP A;  2KYL A;  3DIW A;  3GDU A;  4LMM A;  5I7Z A;  5A2P A;  1X8S A;  2I4S A;  2F5Y A;  5B42 A;  4RI0 A;  2KPL A;  2G5M B;  1RGW A;  2YT8 A;  4Q2Q A;  2AWU A;  2QT5 A;  4NMS A;  2FN5 A;  5HEB A;  2KV8 A;  1WHD A;  2IWO A;  3MH7 A;  2I04 A;  5HET A;  2HGA A;  3KHF A;  2E7K A;  2QKT A;  1UEW A;  3HVQ C;  2GZV A;  5E6P B;  3EGG C;  2AWX A;  3QGL A;  3PV5 A;  1YBO A;  3GSL A;  5FHT A;  2DAZ A;  3OU0 A;  1XZ9 A;  2M0Z A;  1OBZ A;  1R6J A;  1B8Q A;  2R3Y A;  2EEG A;  3QJM A;  3CYY A;  3KZE A;  4Q2O A;  1WFV A;  2KRG A;  3GCO A;  2IWN A;  3CBX A;  4G69 A;  2R4H A;  2PNT A;  2H2B A;  1UEQ A;  3SUZ A;  2Q3G A;  1N7E A;  3KZD A;  3TSV A;  1QAU A;  1N99 A;  3GGE A;  4JL7 A;  1OBX A;  3R0H A;  3AXA A;  2RRM A;  3I18 A;  2ZPM A;  1LCY A;  1TP3 A;  1WHA A;  1UHP A;  2KJK A;  1W9Q A;  2JOA A;  1X45 A;  3WKL A;  4JOJ A;  2JIL A;  5HFE A;  3KDK A;  2EXG A;  2OS6 A;  4YDP A;  3NFK A;  2ZPL A;  2I6V A;  2L97 A;  2EDZ A;  3WKM A;  5HFF A;  4Q6H A;  2K20 A;  1KWA A;  3RL7 A;  4JOF A;  2KL1 A;  5HFC A;  3OTP A;  4YYX A;  2JSN A;  3CS0 A;  2O2T A;  1RY4 A;  3QE1 A;  2Z17 A;  1BE9 A;  3PV4 A;  2EGO A;  4Q3H A;  4O06 A;  1ZUB A;  3KDG A;  1NF3 C;  2LC6 A;  2EJY A;  2YUY A;  4GVC A;  1NTE A;  4NMV A;  1UJD A;  4WYU A;  1V6B A;  1WI4 A;  2CSJ A;  2D8I A;  5HJ1 A;  3GDV A;  2OCS A;  2CS5 A;  2PZD A;  5G1D A;  3GCN A;  2DMZ A;  2EAQ A;  4FLN A;  2P3W A;  3NFL A;  2LC7 A;  2OGP A;  1UJV A;  1MFG A;  1UIT A;  1QAV A;  5GND A;  5HFB A;  2H2C A;  3VQG A;  2KOJ A;  3DJ1 A;  2KOM A;  2FCF A;  5H3J A;  1U3B A;  3QJN A;  1VJ6 A;  2M10 A;  5HF1 A;  2V90 A;  4JOP A;  2FE5 A;  5HDY A;  2OPG A;  1FC9 A;  2HE4 A;  2KJP A;  2QKV A;  1FCF A;  3TMH A;  1U39 A;  3K50 A;  2RCZ A;  3LNY A;  1X9Z A;  3DOR A;  2EEJ A;  2W4F A;  3RL8 A;  2EDV A;  1SOT A;  2VSP A;  4KFV A;  2KBS A;  1X6D A;  4JJ0 A;  2I1N A;  3GJ9 A;  2DC2 A;  4HOP A;  3PV2 A;  3TSZ A;  4K72 A;  2MHO A;  3SOE A;  1MC7 A;  2BYG A;  2Q9V A;  1UEP A;  4N6X A;  1Z87 A;  4NNL A;  1N7F A;  1W9E A;  2L4T A;  3MH6 A;  2F0A A;  1X5Q A;  2VRF A;  1Y8T A;  3NGH A;  3LNX A;  1T2M A;  3RLE A;  4JOG A;  3HPK A;  1Z86 A;  5G1E A;  3GAB A;  5EZ0 A;  3STJ A;  2EEI A;  1D5G A;  1RGR A;  3ID3 A;  4KFW A;  1V5Q A;  1N7T A;  4JOR A;  4H11 A;  2OQS A;  2K1Z A;  3QO6 A;  4JOE A;  4Z33 A;  2L4S A;  3EGH C;  2DKR A;  1N6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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