1HMUA

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 244
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
244
sequence length
674
structure length
674
Chain Sequence
GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
molecule tags Lyase
source organism Pedobacter heparinus
molecule keywords CHONDROITINASE AC
total genus 244
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hmuA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hmuA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hmuA02
1F4HA 3I3EA 1JZ3A 1OJPA 5JMFA 1MMUA 1JYNA 1F1SA 4AQ0A 4D6CA 2WW3A 3VDAA 2WVXA 1EGUA 1F9GA 3T0BA 2D73A 2WMIA 3A24A 1N7QA 1MN0A 3VD3A 4MMHA 3MV11 3DYPA 1OJNA 1HM2A 2BRWA 2WMFA 2WMHA 2WVZA 3NJXA 4OK2A 1N7RA 1LF6A 5JMDA 4D6HA 2WW1A 1LOHA 3MV01 1J0MA 4D6FA 3T0AA 3T08A 1F4AA 1HM3A 2WW0A 3VSMA 2WCOA 4D6IA 1PX3A 1JYWA 1NS4A 1NSVA 1NSRA 1K1YA 4BZGA 3DCDA 1JZ4A 1PX4A 1JZ7A 1LXKA 2WVXB 3I3BA 1OJMA 1NS7A 1ULVA 1SNZA 2WMIB 3NREA 2FUQA 1CB8A 1L7JA 4FNVA 1W3YA 1NS0A 3T0DA 1X1HA 2WMGA 3T2OA 1MMZA 4OZWA 4OK4A 4F13A 1UG9A 2WZSA 4DUVA 3NJVA 2XHNA 3SEPA 4F10A 1N7PA 1RW9A 4OZVA 1K1XA 2E22A 1JOVA 1JZ6A 1SO0A 1L7KA 2ZXQA 3NNBA 2WMJA 3VD5A 3T2PA 3J7HA 1JZ2A 3VDBA 2BRPA 3E80A 3VDCA 4TTGA 1J0NA 3NFVA 3T2QA 2FUTA 1C82A 1LXMA 3AFLA 1Z45A 2CISA 3MUZ1 5A1AA 2CIQA 2WW2A 1K1WA 2WMKA 1RWGA 1RWCA 3VSNA 3Q1NA 3ECQA 1NSSA 2JKPA 1LURA 1HN0A 4D6EA 3K25A 1RWAA 1NSXA 4D6GA 1NSUA 3A0OA 2WVYA 1NKGA 5E1QA 3WFAA 3IAQA 3T09A 1HN1A 1OJOA 1NSMA 4D71A 1YGAA 1RWFA 4D6JA 1HV6A 1HMUA 1JZ5A 4BZFA 1JYVA 1TXKA 3CZJA 2HTAA 3BGAA 4MMIA 3MUY1 1NSZA 3I3DA 3VD4A 2X03A 1X1IA 1N7OA 2HTBA 1JYXA 4BZHA 1RWHA 2JKEA 2WDAA 3DECA 4DUWA 1MMXA 3E7JA 1YQ2A 3MWXA 4D6DA 3OB8A 4RNLA 3DYMA 2ZQ0A 4DUXA 1MMYA 2E24A 3VD9A 4E1YA 1HMWA 3VD7A 1X1JA 1N7NA 3IMHA 4D72A 4NEIA 1NS2A 1NS8A 3DYOA 2BRVX 1QAZA 3E1F1 1LF9A 3OBAA 4OJZA 1JZ8A 2CIRA 2Q1FA 4BZEA 2XSGA 1I8QA 2JKAA 3IAPA 3OS7A 1DP0A
chains in the Genus database with same CATH superfamily
4UFCA 5ILDA 3AMOA 3I3EA 5JMFA 1MMUA 2YFOA 4AQ0A 3T08A 1FP3A 4D6CA 2WW3A 3QPFA 1FCEA 1LD8B 3DSWB 5DHKA 2D73A 3N9HA 4C1SA 3DYPA 4FNPA 3NJXA 2ZIRB 2IEJB 4LNBB 1LF6A 3W7UA 2WW1A 2CFWA 1LOHA 2V8IA 4MU9A 2H6GB 4V1SA 1F4AA 4FNUA 2WCOA 3PZ3B 2WY8A 4D4DA 1N22A 3WA2X 3TY1A 1K1YA 4LIXA 3DCDA 2JJBA 1PX4A 2Y74A 2XFGA 4DLOA 1OJMA 1ULVA 1NS7A 3SDTA 1SNZA 1SIIA 3E1F1 1N1BA 1N95B 5FO9B 2BT3A 1W3YA 1NS0A 1DYUA 1H13A 3WKGA 3WIWA 4FNRA 2PN5A 2GOXA 3EJSA 1G9GA 3QSPA 1MMZA 1JCRB 5JPNB 2WZSA 2G0DA 3GLYA 2F7OA 1H3CA 1S64B 1JS4A 2AFAA 4F10A 4OZVA 3D51A 1JZ6A 1JYWA 2ONGA 3Q73B 1SO0A 2WMJA 3WVFA 4GL3A 1W6KA 3M02A 3VDCA 1J0NA 1WU4A 1KSCA 2OKXA 1IVUA 3NFVA 1UI8A 2D1WA 1TNZB 2V8JA 4ONTA 3G6JB 1XW2A 3BLBA 1G6IA 3ECQA 1IA7A 1NSSA 1LURA 1TQTA 3P2CA 1AYXA 1WMNA 2DROA 4Z4LA 3QXQA 1GXOA 2CWUA 2GZ6A 1NSUA 3ALAA 3A0OA 3M71A 4GTVB 3WIRA 4K35A 1H3AA 1GLMA 3KSLB 5E1QA 3WFAA 2EACA 3EJUA 3T09A 3X41A 3DRAB 1NL4B 2CFDA 2WYIA 1TN7B 1H14A 1KZPB 1CEMA 3Q7AB 1N9AB 3DX0A 1JRQA 2ONHA 1GAHA 1TNOB 5ILHA 3GZKA 1NSZA 4LNGB 3VD4A 3M77A 2X03A 4J5TA 3VXDA 1JYXA 3DSVB 1LD7B 1QSJA 2WDAA 3M74A 1W2ZA 1MMXA 1SA4B 2ZBLA 1W7CA 4AYRA 5M7IA 2XN2A 3EJPA 3MWXA 3OB8A 4FJQA 3WA3A 2E24A 2SQCA 1QX1A 4EHMB 3VD9A 4E1YA 4CJ0A 1N9EA 3VD7A 1X1JA 4FUSA 3W5MA 2FV0A 5IK6A 3SDQA 4D72A 4NEIA 2B39A 1H37A 5ILJA 3DYOA 5KBPA 5ILZA 1WMOA 3EU8A 1LF9A 4GAXA 3D4ZA 4KFDA 1GA2A 3Q7FB 2XWJB 4CJ1A 4L0GA 1V7XA 5CA3A 1W5ZA 3PYBA 4LNVA 1TQSA 3SFXB 5IK9A 3M7BA 3IAPA 1KWFA 1F4HA 2WIIB 3M00A 5AGDA 2WOFA 3DDGA 2CWTA 3M7CA 1TF4A 2OW6A 4KFEA 2H6IB 1EGUA 1F9GA 1FO2A 2WVXA 4EV2A 2WMIA 3A24A 1GHQA 1N7QA 1PS3A 2PNCA 1FT2B 1W6JA 3PYAA 3HXDB 2WMFA 2WMHA 1KRFA 1N7RA 3PZ1B 2EADA 5GW7A 3QG0A 3HIIA 3BVUA 3A3VA 2Y73A 1FMIA 4KKJA 2ZZRA 4D1IA 1PX3A 1WZZA 4Q88A 1NS4A 2AHFA 1NSVA 3M7LA 4BZGA 1TNUB 1LXKA 3K5TA 3UD2A 3EJRA 2DRQA 1CB8A 2PMVA 1L7JA 1HWWA 1N4QB 2CQTA 3BVTA 1LVNA 1D6YA 4V1RA 4DI5A 3QDEA 3QWTA 1V7VA 4DUVA 3ANJA 3DSXB 3SEPA 1N7PA 3D50A 5IL8A 1N4RB 1V5CA 3PMMA 1W6CA 3NBBA 1H36A 1FAEA 1TQWA 4GTMB 3VDBA 5EATA 3SFYB 2E2UA 1L1YA 1DOGA 3T2QA 2FUTA 2VN4A 3VW5A 2BB5A 2XN0A 2WMKA 1RWGA 3WKIA 3VSNA 1WMPA 3BUQA 2C11A 2DRSA 2V3PA 2JKPA 5IK0A 1HN0A 3M76A 2RI9A 2WVYA 4MBGB 2VN7A 3WKHA 2OQEC 3IAQA 1NSMA 1YGAA 3BUDA 2RGKA 3RENA 4D6JA 1RJOA 1HV6A 4YDEB 4BZFA 2F18A 1IVWA 3CZJA 2HTAA 2OOVA 1KREA 3MUY1 4TF4A 1X1IA 1H35A 1GAIA 3RX5A 3S4CA 4BOJA 1OACA 1QALA 1W6GA 3KIIA 2JKEA 2RI8A 1QAKA 1NI1B 5DGQA 1R76A 2OW7A 1X81B 3KQ4A 3MPHA 1FPPB 3E7JA 3G4DA 1YQ2A 1D6ZA 1IS9A 3DYMA 2JG0A 4FNSA 2D8LA 4BTYA 2WINB 1O5MB 3H3KA 4D4AA 5IL3A 4L9PB 3EU5B 3IMHA 1IA6A 3BS6A 1H12A 1NS2A 2ALWA 1NS8A 1DL2A 4M76A 3M73A 1NC5A 3OEDA 3W7SA 1IU7A 5FO8B 3N0FA 2W0QA 5E2JA 3OXUA 1TNBB 1JZ3A 1OJPA 1JYNA 3CIHA 2F7RA 3SX1A 2CFKA 3KLSA 1KZOB 5JPMB 2R2LB 1F9DA 4XUVA 4ZRQA 3X3ZA 1MN0A 4AYQA 1UMPA 1HM2A 2BRWA 2XN1A 2DRRA 2WVZA 1N94B 5JMDA 4D6HA 3MV01 1J0MA 3HXEB 2WW0A 3AMOB 1HXKA 3VSMA 1WU6A 1FO3A 3X3YA 1NSRA 1TN6B 3BUIA 1FT1B 2V3NA 3S4AA 4FXGB 1QWUA 4KFFA 3QXFA 3SDRA 1MZCB 2CFLA 2CG0A 1JZ7A 2Z07A 3BLCA 2D5JA 5FO7B 3SDUA 2FUQA 4Q2BA 1O7DD 5EASA 2OOVC 2OQEA 1AGMA 2BBCA 1UT9A 3T2OA 2H6FB 3RX7A 3HIGA 4OZWA 4OK4A 1UG9A 3E30B 2E2VA 1KSDA 3NJVA 4WU0A 3T33A 1G87A 1RW9A 3S4BA 1K1XA 3QT3A 2F6DA 4GTQB 3E34B 1N23A 1US1A 4TXTA 3QFZA 2ZXQA 3VD5A 4AYPA 3T2PA 4Z4JA 3J7HA 2I07B 2ZL8A 2J5CA 3QRYA 3EJTA 4DLQA 5IKAA 4GTSB 1SPUA 2G02A 1C3DA 1N4SB 3AFLA 1O6QA 4GTTB 3MUZ1 3H7LA 2CIQA 3QT9A 3M72A 5GY3A 3UD1A 1K1WA 4L6XA 1F9OA 3Q1NA 4DODA 3T0UA 2FV1A 3DSUB 3EZ8A 4GTPB 3K25A 1XWTA 3Q78B 1S63B 4D6GA 4ZH1A 2F7PA 3PQIA 3W5NA 1HN1A 2GH4A 4WVBA 3D5RA 4D71A 3E73A 3BVWA 1O6RA 4D4BA 1RWFA 4EL8A 3EJQA 3KBUC 2WYNA 3HXFB 2WY7A 2ZISB 3DSSB 3DDFA 1LTXB 1V7WA 2FYVA 4MMIA 1D8EB 1O1RB 3I3DA 3M7EA 3CV5A 1H39A 4RNQA 3X3XA 3DECA 1SIHA 4DUWA 3SQCA 4QT9A 1WU5A 2WOHA 1QAFA 5FOBB 3KSQB 3DSTB 4DOEA 2WGQA 3GT5A 1XWQA 4GTOB 3PGBA 3BVXA 4RNLA 2F1AA 1TU5A 5DGRA 1AV4A 1RKYA 5KKBA 3RX8A 1HMWA 3CZSA 4KTRA 3ACSA 4BTXA 1UI7A 3Q79B 3DX1A 3E33B 5CD2A 1N4PB 1QAZA 3C72B 3EQAA 3M75A 4GTRB 3S4DA 2F1BA 1SQCA 2XQWA 4OJZA 1JCSB 5EAUA 3W7XA 1X9DA 4FNQA 3M01A 2CIRA 5C05A 2F0YB 4BZEA 3WC3A 3DX4A 2XSGA 4KKIA 1AVLA 1DP0A 3ANIA 2H6HB 3HXBB 3W7TA 1F1SA 1HXAA 4D4CA 3LOYA 3VDAA 3T0BA 3RSYA 2CG1A 2P0VA 3VD3A 1L2AA 4BTWA 4MMHA 4D8OA 3MV11 1OJNA 1GXMA 4AYOA 1HXGA 1H54A 3ACTA 5ILKA 3QR8A 3WKFA 4OK2A 4EV5A 2QNOA 4YDOB 1KFGA 4D6FA 2YFNA 2NOJA 2BEDB 3T0AA 1O1SB 1HM3A 5CZLA 2WO0A 3S9VA 1QBQB 2V8KA 4D6IA 1W4NA 1N24A 2CFGA 3CZNA 1IVVA 1N1ZA 4CE7A 1TQUA 3Q75B 3CU7A 1JZ4A 2CQSA 2WVXB 3NREA 3I3BA 1JCQB 1O6HA 2WMIB 3U7VA 3SAEA 1KKTA 4FNVA 1DCEB 3H2WA 3KN4A 3T0DA 1X1HA 3P5PA 3F59A 2WMGA 3WIQA 2NVPA 1FBOA 1N21A 3KBTC 1TQVA 2EABA 4F13A 3BVVA 1AVKA 1D6UA 2XHNA 1HX9A 3EUVB 4WVCA 1QQFA 3WUXA 2E22A 1JOVA 3PZ4B 1TN8B 3NNBA 1L7KA 1SA5B 5M7YA 1CLCA 1HTYA 3NBJA 1JZ2A 3E37B 3E6UA 1A2VA 3DX3A 2BRPA 3E80A 4TTGA 1NXCA 1N20A 2KXSA 2E2TA 4BOKA 1C82A 1LXMA 2AHGA 1O79A 1R33A 2A8ZA 3P5RA 1Z45A 2CISA 5A1AA 2WW2A 2YIKA 4FXKB 3BUBA 1QWNA 1RWCA 4KTPA 4ZG8A 2C10A 3BUPA 4K3AA 1FBWA 2JF4A 5ILYA 4D6EA 3D3IA 3LZ9A 3TF4A 2WYHA 1RWAA 1NSXA 1D8DB 3SXXA 3X40A 3DX2A 1NKGA 1HZFA 2RDYA 1HCUA 3HI7A 1OJOA 3QFYA 3ANKA 1V5DA 1HMUA 2XWBB 3PZ2B 3D52A 1JZ5A 1JYVA 3K7XA 1EKMA 4D94A 1TXKA 2EAEA 5GZKA 5ILIA 1RQ5A 3D5SA 4D1JA 3HXCB 2F7QA 3BGAA 3RRSA 1PU4A 2B4FA 1GSZA 1KS8A 3M78A 1N7OA 1IVXA 5MEHA 2HTBA 3G4FA 4YCRA 3ON6A 3X17A 1G9JA 2CWVA 4BZHA 1RWHA 1VD5A 3X42A 1IQXA 5DHIA 5IM1A 1KSIA 3AFJA 2A73B 4WVAA 1H3BA 1GXNA 4ZRPA 2YX9A 1IQYA 4D6DA 3E32B 2ZQ0A 4DUXA 1MMYA 1O1TB 4JJJA 3MI6A 3D4YA 3DPYB 1R34A 4FNTA 1N7NA 1HXCA 2KXRA 2BRVX 3OBAA 2FBAA 1JZ8A 3W7WA 3K11A 2Q1FA 2BB6A 5IKHA 1K72A 1I8QA 1TNYB 4ZH5A 3SDVA 3RJ3A 3N0GA 2FUZA 2JKAA 3OS7A 3LVTA
chains in the Genus database with same CATH topology
1F4HA 3I3EA 1JZ3A 1OJPA 5JMFA 1MMUA 1JYNA 1F1SA 4AQ0A 4D6CA 2WW3A 3VDAA 2WVXA 1EGUA 1F9GA 3T0BA 2D73A 2WMIA 3A24A 1N7QA 1MN0A 3VD3A 4MMHA 3MV11 3DYPA 1OJNA 1HM2A 2BRWA 2WMFA 2WMHA 2WVZA 3NJXA 4OK2A 1N7RA 1LF6A 5JMDA 4D6HA 2WW1A 1LOHA 3MV01 1J0MA 4D6FA 3T0AA 3T08A 1F4AA 1HM3A 2WW0A 3VSMA 2WCOA 4D6IA 1PX3A 1JYWA 1NS4A 1NSVA 3TY1A 1NSRA 1K1YA 4BZGA 3DCDA 1JZ4A 1PX4A 1JZ7A 1LXKA 2WVXB 3I3BA 1OJMA 1NS7A 1ULVA 1SNZA 2WMIB 3BLCA 3NREA 2FUQA 1CB8A 1L7JA 4FNVA 1W3YA 1NS0A 3T0DA 1X1HA 2WMGA 3T2OA 1MMZA 4OZWA 4OK4A 4F13A 1UG9A 2WZSA 4DUVA 3NJVA 2XHNA 3SEPA 4F10A 1N7PA 1RW9A 4OZVA 1K1XA 2E22A 1JOVA 1JZ6A 1SO0A 1L7KA 2ZXQA 3NNBA 2WMJA 3VD5A 3T2PA 3WVFA 3J7HA 1JZ2A 3VDBA 2BRPA 3E80A 3VDCA 4TTGA 1J0NA 3NFVA 3T2QA 2FUTA 1C82A 1LXMA 3AFLA 1Z45A 2CISA 3MUZ1 5A1AA 2CIQA 2WW2A 1K1WA 2WMKA 1RWGA 1RWCA 3VSNA 3Q1NA 3ECQA 1NSSA 2JKPA 1LURA 1HN0A 4D6EA 3K25A 1RWAA 1NSXA 4D6GA 1NSUA 3A0OA 2WVYA 1NKGA 5E1QA 3WFAA 3IAQA 3T09A 1HN1A 1OJOA 1NSMA 4D71A 1YGAA 1RWFA 4D6JA 1HV6A 1HMUA 1JZ5A 4BZFA 1JYVA 1TXKA 3CZJA 2HTAA 3BGAA 4MMIA 3MUY1 1NSZA 3I3DA 3VD4A 2X03A 4J5TA 1X1IA 1N7OA 2HTBA 1JYXA 4BZHA 1RWHA 2JKEA 2WDAA 3DECA 4DUWA 1MMXA 3E7JA 1YQ2A 3MWXA 4D6DA 3OB8A 4RNLA 3DYMA 2ZQ0A 4DUXA 1MMYA 2E24A 3VD9A 4E1YA 1HMWA 3VD7A 1X1JA 1N7NA 3IMHA 4D72A 3BS6A 4NEIA 1NS2A 1NS8A 3DYOA 2BRVX 1QAZA 3E1F1 1LF9A 3OBAA 4OJZA 1JZ8A 2CIRA 2Q1FA 4BZEA 2XSGA 1I8QA 2JKAA 3IAPA 3OS7A 1DP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F4H A;  3I3E A;  1JZ3 A;  1OJP A;  5JMF A;  1MMU A;  1JYN A;  1F1S A;  4AQ0 A;  4D6C A;  2WW3 A;  3VDA A;  2WVX A;  1EGU A;  1F9G A;  3T0B A;  2D73 A;  2WMI A;  3A24 A;  1N7Q A;  1MN0 A;  3VD3 A;  4MMH A;  3MV1 1;  3DYP A;  1OJN A;  1HM2 A;  2BRW A;  2WMF A;  2WMH A;  2WVZ A;  3NJX A;  4OK2 A;  1N7R A;  1LF6 A;  5JMD A;  4D6H A;  2WW1 A;  1LOH A;  3MV0 1;  1J0M A;  4D6F A;  3T0A A;  3T08 A;  1F4A A;  1HM3 A;  2WW0 A;  3VSM A;  2WCO A;  4D6I A;  1PX3 A;  1JYW A;  1NS4 A;  1NSV A;  1NSR A;  1K1Y A;  4BZG A;  3DCD A;  1JZ4 A;  1PX4 A;  1JZ7 A;  1LXK A;  2WVX B;  3I3B A;  1OJM A;  1NS7 A;  1ULV A;  1SNZ A;  2WMI B;  3NRE A;  2FUQ A;  1CB8 A;  1L7J A;  4FNV A;  1W3Y A;  1NS0 A;  3T0D A;  1X1H A;  2WMG A;  3T2O A;  1MMZ A;  4OZW A;  4OK4 A;  4F13 A;  1UG9 A;  2WZS A;  4DUV A;  3NJV A;  2XHN A;  3SEP A;  4F10 A;  1N7P A;  1RW9 A;  4OZV A;  1K1X A;  2E22 A;  1JOV A;  1JZ6 A;  1SO0 A;  1L7K A;  2ZXQ A;  3NNB A;  2WMJ A;  3VD5 A;  3T2P A;  3J7H A;  1JZ2 A;  3VDB A;  2BRP A;  3E80 A;  3VDC A;  4TTG A;  1J0N A;  3NFV A;  3T2Q A;  2FUT A;  1C82 A;  1LXM A;  3AFL A;  1Z45 A;  2CIS A;  3MUZ 1;  5A1A A;  2CIQ A;  2WW2 A;  1K1W A;  2WMK A;  1RWG A;  1RWC A;  3VSN A;  3Q1N A;  3ECQ A;  1NSS A;  2JKP A;  1LUR A;  1HN0 A;  4D6E A;  3K25 A;  1RWA A;  1NSX A;  4D6G A;  1NSU A;  3A0O A;  2WVY A;  1NKG A;  5E1Q A;  3WFA A;  3IAQ A;  3T09 A;  1HN1 A;  1OJO A;  1NSM A;  4D71 A;  1YGA A;  1RWF A;  4D6J A;  1HV6 A;  1HMU A;  1JZ5 A;  4BZF A;  1JYV A;  1TXK A;  3CZJ A;  2HTA A;  3BGA A;  4MMI A;  3MUY 1;  1NSZ A;  3I3D A;  3VD4 A;  2X03 A;  1X1I A;  1N7O A;  2HTB A;  1JYX A;  4BZH A;  1RWH A;  2JKE A;  2WDA A;  3DEC A;  4DUW A;  1MMX A;  3E7J A;  1YQ2 A;  3MWX A;  4D6D A;  3OB8 A;  4RNL A;  3DYM A;  2ZQ0 A;  4DUX A;  1MMY A;  2E24 A;  3VD9 A;  4E1Y A;  1HMW A;  3VD7 A;  1X1J A;  1N7N A;  3IMH A;  4D72 A;  4NEI A;  1NS2 A;  1NS8 A;  3DYO A;  2BRV X;  1QAZ A;  3E1F 1;  1LF9 A;  3OBA A;  4OJZ A;  1JZ8 A;  2CIR A;  2Q1F A;  4BZE A;  2XSG A;  1I8Q A;  2JKA A;  3IAP A;  3OS7 A;  1DP0 A; 
#chains in the Genus database with same CATH topology
 4UFC A;  5ILD A;  3AMO A;  3I3E A;  5JMF A;  1MMU A;  2YFO A;  4AQ0 A;  3T08 A;  1FP3 A;  4D6C A;  2WW3 A;  3QPF A;  1FCE A;  1LD8 B;  3DSW B;  5DHK A;  2D73 A;  3N9H A;  4C1S A;  3DYP A;  4FNP A;  3NJX A;  2ZIR B;  2IEJ B;  4LNB B;  1LF6 A;  3W7U A;  2WW1 A;  2CFW A;  1LOH A;  2V8I A;  4MU9 A;  2H6G B;  4V1S A;  1F4A A;  4FNU A;  2WCO A;  3PZ3 B;  2WY8 A;  4D4D A;  1N22 A;  3WA2 X;  3TY1 A;  1K1Y A;  4LIX A;  3DCD A;  2JJB A;  1PX4 A;  2Y74 A;  2XFG A;  4DLO A;  1OJM A;  1ULV A;  1NS7 A;  3SDT A;  1SNZ A;  1SII A;  3E1F 1;  1N1B A;  1N95 B;  5FO9 B;  2BT3 A;  1W3Y A;  1NS0 A;  1DYU A;  1H13 A;  3WKG A;  3WIW A;  4FNR A;  2PN5 A;  2GOX A;  3EJS A;  1G9G A;  3QSP A;  1MMZ A;  1JCR B;  5JPN B;  2WZS A;  2G0D A;  3GLY A;  2F7O A;  1H3C A;  1S64 B;  1JS4 A;  2AFA A;  4F10 A;  4OZV A;  3D51 A;  1JZ6 A;  1JYW A;  2ONG A;  3Q73 B;  1SO0 A;  2WMJ A;  3WVF A;  4GL3 A;  1W6K A;  3M02 A;  3VDC A;  1J0N A;  1WU4 A;  1KSC A;  2OKX A;  1IVU A;  3NFV A;  1UI8 A;  2D1W A;  1TNZ B;  2V8J A;  4ONT A;  3G6J B;  1XW2 A;  3BLB A;  1G6I A;  3ECQ A;  1IA7 A;  1NSS A;  1LUR A;  1TQT A;  3P2C A;  1AYX A;  1WMN A;  2DRO A;  4Z4L A;  3QXQ A;  1GXO A;  2CWU A;  2GZ6 A;  1NSU A;  3ALA A;  3A0O A;  3M71 A;  4GTV B;  3WIR A;  4K35 A;  1H3A A;  1GLM A;  3KSL B;  5E1Q A;  3WFA A;  2EAC A;  3EJU A;  3T09 A;  3X41 A;  3DRA B;  1NL4 B;  2CFD A;  2WYI A;  1TN7 B;  1H14 A;  1KZP B;  1CEM A;  3Q7A B;  1N9A B;  3DX0 A;  1JRQ A;  2ONH A;  1GAH A;  1TNO B;  5ILH A;  3GZK A;  1NSZ A;  4LNG B;  3VD4 A;  3M77 A;  2X03 A;  4J5T A;  3VXD A;  1JYX A;  3DSV B;  1LD7 B;  1QSJ A;  2WDA A;  3M74 A;  1W2Z A;  1MMX A;  1SA4 B;  2ZBL A;  1W7C A;  4AYR A;  5M7I A;  2XN2 A;  3EJP A;  3MWX A;  3OB8 A;  4FJQ A;  3WA3 A;  2E24 A;  2SQC A;  1QX1 A;  4EHM B;  3VD9 A;  4E1Y A;  4CJ0 A;  1N9E A;  3VD7 A;  1X1J A;  4FUS A;  3W5M A;  2FV0 A;  5IK6 A;  3SDQ A;  4D72 A;  4NEI A;  2B39 A;  1H37 A;  5ILJ A;  3DYO A;  5KBP A;  5ILZ A;  1WMO A;  3EU8 A;  1LF9 A;  4GAX A;  3D4Z A;  4KFD A;  1GA2 A;  3Q7F B;  2XWJ B;  4CJ1 A;  4L0G A;  1V7X A;  5CA3 A;  1W5Z A;  3PYB A;  4LNV A;  1TQS A;  3SFX B;  5IK9 A;  3M7B A;  3IAP A;  1KWF A;  1F4H A;  2WII B;  3M00 A;  5AGD A;  2WOF A;  3DDG A;  2CWT A;  3M7C A;  1TF4 A;  2OW6 A;  4KFE A;  2H6I B;  1EGU A;  1F9G A;  1FO2 A;  2WVX A;  4EV2 A;  2WMI A;  3A24 A;  1GHQ A;  1N7Q A;  1PS3 A;  2PNC A;  1FT2 B;  1W6J A;  3PYA A;  3HXD B;  2WMF A;  2WMH A;  1KRF A;  1N7R A;  3PZ1 B;  2EAD A;  5GW7 A;  3QG0 A;  3HII A;  3BVU A;  3A3V A;  2Y73 A;  1FMI A;  4KKJ A;  2ZZR A;  4D1I A;  1PX3 A;  1WZZ A;  4Q88 A;  1NS4 A;  2AHF A;  1NSV A;  3M7L A;  4BZG A;  1TNU B;  1LXK A;  3K5T A;  3UD2 A;  3EJR A;  2DRQ A;  1CB8 A;  2PMV A;  1L7J A;  1HWW A;  1N4Q B;  2CQT A;  3BVT A;  1LVN A;  1D6Y A;  4V1R A;  4DI5 A;  3QDE A;  3QWT A;  1V7V A;  4DUV A;  3ANJ A;  3DSX B;  3SEP A;  1N7P A;  3D50 A;  5IL8 A;  1N4R B;  1V5C A;  3PMM A;  1W6C A;  3NBB A;  1H36 A;  1FAE A;  1TQW A;  4GTM B;  3VDB A;  5EAT A;  3SFY B;  2E2U A;  1L1Y A;  1DOG A;  3T2Q A;  2FUT A;  2VN4 A;  3VW5 A;  2BB5 A;  2XN0 A;  2WMK A;  1RWG A;  3WKI A;  3VSN A;  1WMP A;  3BUQ A;  2C11 A;  2DRS A;  2V3P A;  2JKP A;  5IK0 A;  1HN0 A;  3M76 A;  2RI9 A;  2WVY A;  4MBG B;  2VN7 A;  3WKH A;  2OQE C;  3IAQ A;  1NSM A;  1YGA A;  3BUD A;  2RGK A;  3REN A;  4D6J A;  1RJO A;  1HV6 A;  4YDE B;  4BZF A;  2F18 A;  1IVW A;  3CZJ A;  2HTA A;  2OOV A;  1KRE A;  3MUY 1;  4TF4 A;  1X1I A;  1H35 A;  1GAI A;  3RX5 A;  3S4C A;  4BOJ A;  1OAC A;  1QAL A;  1W6G A;  3KII A;  2JKE A;  2RI8 A;  1QAK A;  1NI1 B;  5DGQ A;  1R76 A;  2OW7 A;  1X81 B;  3KQ4 A;  3MPH A;  1FPP B;  3E7J A;  3G4D A;  1YQ2 A;  1D6Z A;  1IS9 A;  3DYM A;  2JG0 A;  4FNS A;  2D8L A;  4BTY A;  2WIN B;  1O5M B;  3H3K A;  4D4A A;  5IL3 A;  4L9P B;  3EU5 B;  3IMH A;  1IA6 A;  3BS6 A;  1H12 A;  1NS2 A;  2ALW A;  1NS8 A;  1DL2 A;  4M76 A;  3M73 A;  1NC5 A;  3OED A;  3W7S A;  1IU7 A;  5FO8 B;  3N0F A;  2W0Q A;  5E2J A;  3OXU A;  1TNB B;  1JZ3 A;  1OJP A;  1JYN A;  3CIH A;  2F7R A;  3SX1 A;  2CFK A;  3KLS A;  1KZO B;  5JPM B;  2R2L B;  1F9D A;  4XUV A;  4ZRQ A;  3X3Z A;  1MN0 A;  4AYQ A;  1UMP A;  1HM2 A;  2BRW A;  2XN1 A;  2DRR A;  2WVZ A;  1N94 B;  5JMD A;  4D6H A;  3MV0 1;  1J0M A;  3HXE B;  2WW0 A;  3AMO B;  1HXK A;  3VSM A;  1WU6 A;  1FO3 A;  3X3Y A;  1NSR A;  1TN6 B;  3BUI A;  1FT1 B;  2V3N A;  3S4A A;  4FXG B;  1QWU A;  4KFF A;  3QXF A;  3SDR A;  1MZC B;  2CFL A;  2CG0 A;  1JZ7 A;  2Z07 A;  3BLC A;  2D5J A;  5FO7 B;  3SDU A;  2FUQ A;  4Q2B A;  1O7D D;  5EAS A;  2OOV C;  2OQE A;  1AGM A;  2BBC A;  1UT9 A;  3T2O A;  2H6F B;  3RX7 A;  3HIG A;  4OZW A;  4OK4 A;  1UG9 A;  3E30 B;  2E2V A;  1KSD A;  3NJV A;  4WU0 A;  3T33 A;  1G87 A;  1RW9 A;  3S4B A;  1K1X A;  3QT3 A;  2F6D A;  4GTQ B;  3E34 B;  1N23 A;  1US1 A;  4TXT A;  3QFZ A;  2ZXQ A;  3VD5 A;  4AYP A;  3T2P A;  4Z4J A;  3J7H A;  2I07 B;  2ZL8 A;  2J5C A;  3QRY A;  3EJT A;  4DLQ A;  5IKA A;  4GTS B;  1SPU A;  2G02 A;  1C3D A;  1N4S B;  3AFL A;  1O6Q A;  4GTT B;  3MUZ 1;  3H7L A;  2CIQ A;  3QT9 A;  3M72 A;  5GY3 A;  3UD1 A;  1K1W A;  4L6X A;  1F9O A;  3Q1N A;  4DOD A;  3T0U A;  2FV1 A;  3DSU B;  3EZ8 A;  4GTP B;  3K25 A;  1XWT A;  3Q78 B;  1S63 B;  4D6G A;  4ZH1 A;  2F7P A;  3PQI A;  3W5N A;  1HN1 A;  2GH4 A;  4WVB A;  3D5R A;  4D71 A;  3E73 A;  3BVW A;  1O6R A;  4D4B A;  1RWF A;  4EL8 A;  3EJQ A;  3KBU C;  2WYN A;  3HXF B;  2WY7 A;  2ZIS B;  3DSS B;  3DDF A;  1LTX B;  1V7W A;  2FYV A;  4MMI A;  1D8E B;  1O1R B;  3I3D A;  3M7E A;  3CV5 A;  1H39 A;  4RNQ A;  3X3X A;  3DEC A;  1SIH A;  4DUW A;  3SQC A;  4QT9 A;  1WU5 A;  2WOH A;  1QAF A;  5FOB B;  3KSQ B;  3DST B;  4DOE A;  2WGQ A;  3GT5 A;  1XWQ A;  4GTO B;  3PGB A;  3BVX A;  4RNL A;  2F1A A;  1TU5 A;  5DGR A;  1AV4 A;  1RKY A;  5KKB A;  3RX8 A;  1HMW A;  3CZS A;  4KTR A;  3ACS A;  4BTX A;  1UI7 A;  3Q79 B;  3DX1 A;  3E33 B;  5CD2 A;  1N4P B;  1QAZ A;  3C72 B;  3EQA A;  3M75 A;  4GTR B;  3S4D A;  2F1B A;  1SQC A;  2XQW A;  4OJZ A;  1JCS B;  5EAU A;  3W7X A;  1X9D A;  4FNQ A;  3M01 A;  2CIR A;  5C05 A;  2F0Y B;  4BZE A;  3WC3 A;  3DX4 A;  2XSG A;  4KKI A;  1AVL A;  1DP0 A;  3ANI A;  2H6H B;  3HXB B;  3W7T A;  1F1S A;  1HXA A;  4D4C A;  3LOY A;  3VDA A;  3T0B A;  3RSY A;  2CG1 A;  2P0V A;  3VD3 A;  1L2A A;  4BTW A;  4MMH A;  4D8O A;  3MV1 1;  1OJN A;  1GXM A;  4AYO A;  1HXG A;  1H54 A;  3ACT A;  5ILK A;  3QR8 A;  3WKF A;  4OK2 A;  4EV5 A;  2QNO A;  4YDO B;  1KFG A;  4D6F A;  2YFN A;  2NOJ A;  2BED B;  3T0A A;  1O1S B;  1HM3 A;  5CZL A;  2WO0 A;  3S9V A;  1QBQ B;  2V8K A;  4D6I A;  1W4N A;  1N24 A;  2CFG A;  3CZN A;  1IVV A;  1N1Z A;  4CE7 A;  1TQU A;  3Q75 B;  3CU7 A;  1JZ4 A;  2CQS A;  2WVX B;  3NRE A;  3I3B A;  1JCQ B;  1O6H A;  2WMI B;  3U7V A;  3SAE A;  1KKT A;  4FNV A;  1DCE B;  3H2W A;  3KN4 A;  3T0D A;  1X1H A;  3P5P A;  3F59 A;  2WMG A;  3WIQ A;  2NVP A;  1FBO A;  1N21 A;  3KBT C;  1TQV A;  2EAB A;  4F13 A;  3BVV A;  1AVK A;  1D6U A;  2XHN A;  1HX9 A;  3EUV B;  4WVC A;  1QQF A;  3WUX A;  2E22 A;  1JOV A;  3PZ4 B;  1TN8 B;  3NNB A;  1L7K A;  1SA5 B;  5M7Y A;  1CLC A;  1HTY A;  3NBJ A;  1JZ2 A;  3E37 B;  3E6U A;  1A2V A;  3DX3 A;  2BRP A;  3E80 A;  4TTG A;  1NXC A;  1N20 A;  2KXS A;  2E2T A;  4BOK A;  1C82 A;  1LXM A;  2AHG A;  1O79 A;  1R33 A;  2A8Z A;  3P5R A;  1Z45 A;  2CIS A;  5A1A A;  2WW2 A;  2YIK A;  4FXK B;  3BUB A;  1QWN A;  1RWC A;  4KTP A;  4ZG8 A;  2C10 A;  3BUP A;  4K3A A;  1FBW A;  2JF4 A;  5ILY A;  4D6E A;  3D3I A;  3LZ9 A;  3TF4 A;  2WYH A;  1RWA A;  1NSX A;  1D8D B;  3SXX A;  3X40 A;  3DX2 A;  1NKG A;  1HZF A;  2RDY A;  1HCU A;  3HI7 A;  1OJO A;  3QFY A;  3ANK A;  1V5D A;  1HMU A;  2XWB B;  3PZ2 B;  3D52 A;  1JZ5 A;  1JYV A;  3K7X A;  1EKM A;  4D94 A;  1TXK A;  2EAE A;  5GZK A;  5ILI A;  1RQ5 A;  3D5S A;  4D1J A;  3HXC B;  2F7Q A;  3BGA A;  3RRS A;  1PU4 A;  2B4F A;  1GSZ A;  1KS8 A;  3M78 A;  1N7O A;  1IVX A;  5MEH A;  2HTB A;  3G4F A;  4YCR A;  3ON6 A;  3X17 A;  1G9J A;  2CWV A;  4BZH A;  1RWH A;  1VD5 A;  3X42 A;  1IQX A;  5DHI A;  5IM1 A;  1KSI A;  3AFJ A;  2A73 B;  4WVA A;  1H3B A;  1GXN A;  4ZRP A;  2YX9 A;  1IQY A;  4D6D A;  3E32 B;  2ZQ0 A;  4DUX A;  1MMY A;  1O1T B;  4JJJ A;  3MI6 A;  3D4Y A;  3DPY B;  1R34 A;  4FNT A;  1N7N A;  1HXC A;  2KXR A;  2BRV X;  3OBA A;  2FBA A;  1JZ8 A;  3W7W A;  3K11 A;  2Q1F A;  2BB6 A;  5IKH A;  1K72 A;  1I8Q A;  1TNY B;  4ZH5 A;  3SDV A;  3RJ3 A;  3N0G A;  2FUZ A;  2JKA A;  3OS7 A;  3LVT A; 
#chains in the Genus database with same CATH homology
 1F4H A;  3I3E A;  1JZ3 A;  1OJP A;  5JMF A;  1MMU A;  1JYN A;  1F1S A;  4AQ0 A;  4D6C A;  2WW3 A;  3VDA A;  2WVX A;  1EGU A;  1F9G A;  3T0B A;  2D73 A;  2WMI A;  3A24 A;  1N7Q A;  1MN0 A;  3VD3 A;  4MMH A;  3MV1 1;  3DYP A;  1OJN A;  1HM2 A;  2BRW A;  2WMF A;  2WMH A;  2WVZ A;  3NJX A;  4OK2 A;  1N7R A;  1LF6 A;  5JMD A;  4D6H A;  2WW1 A;  1LOH A;  3MV0 1;  1J0M A;  4D6F A;  3T0A A;  3T08 A;  1F4A A;  1HM3 A;  2WW0 A;  3VSM A;  2WCO A;  4D6I A;  1PX3 A;  1JYW A;  1NS4 A;  1NSV A;  3TY1 A;  1NSR A;  1K1Y A;  4BZG A;  3DCD A;  1JZ4 A;  1PX4 A;  1JZ7 A;  1LXK A;  2WVX B;  3I3B A;  1OJM A;  1NS7 A;  1ULV A;  1SNZ A;  2WMI B;  3BLC A;  3NRE A;  2FUQ A;  1CB8 A;  1L7J A;  4FNV A;  1W3Y A;  1NS0 A;  3T0D A;  1X1H A;  2WMG A;  3T2O A;  1MMZ A;  4OZW A;  4OK4 A;  4F13 A;  1UG9 A;  2WZS A;  4DUV A;  3NJV A;  2XHN A;  3SEP A;  4F10 A;  1N7P A;  1RW9 A;  4OZV A;  1K1X A;  2E22 A;  1JOV A;  1JZ6 A;  1SO0 A;  1L7K A;  2ZXQ A;  3NNB A;  2WMJ A;  3VD5 A;  3T2P A;  3WVF A;  3J7H A;  1JZ2 A;  3VDB A;  2BRP A;  3E80 A;  3VDC A;  4TTG A;  1J0N A;  3NFV A;  3T2Q A;  2FUT A;  1C82 A;  1LXM A;  3AFL A;  1Z45 A;  2CIS A;  3MUZ 1;  5A1A A;  2CIQ A;  2WW2 A;  1K1W A;  2WMK A;  1RWG A;  1RWC A;  3VSN A;  3Q1N A;  3ECQ A;  1NSS A;  2JKP A;  1LUR A;  1HN0 A;  4D6E A;  3K25 A;  1RWA A;  1NSX A;  4D6G A;  1NSU A;  3A0O A;  2WVY A;  1NKG A;  5E1Q A;  3WFA A;  3IAQ A;  3T09 A;  1HN1 A;  1OJO A;  1NSM A;  4D71 A;  1YGA A;  1RWF A;  4D6J A;  1HV6 A;  1HMU A;  1JZ5 A;  4BZF A;  1JYV A;  1TXK A;  3CZJ A;  2HTA A;  3BGA A;  4MMI A;  3MUY 1;  1NSZ A;  3I3D A;  3VD4 A;  2X03 A;  4J5T A;  1X1I A;  1N7O A;  2HTB A;  1JYX A;  4BZH A;  1RWH A;  2JKE A;  2WDA A;  3DEC A;  4DUW A;  1MMX A;  3E7J A;  1YQ2 A;  3MWX A;  4D6D A;  3OB8 A;  4RNL A;  3DYM A;  2ZQ0 A;  4DUX A;  1MMY A;  2E24 A;  3VD9 A;  4E1Y A;  1HMW A;  3VD7 A;  1X1J A;  1N7N A;  3IMH A;  4D72 A;  3BS6 A;  4NEI A;  1NS2 A;  1NS8 A;  3DYO A;  2BRV X;  1QAZ A;  3E1F 1;  1LF9 A;  3OBA A;  4OJZ A;  1JZ8 A;  2CIR A;  2Q1F A;  4BZE A;  2XSG A;  1I8Q A;  2JKA A;  3IAP A;  3OS7 A;  1DP0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...