2W7RA

Structure of the pdz domain of human microtubule associated serine- threonine kinase 4
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
96
structure length
95
Chain Sequence
QPIVIHSSKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTETSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 4
total genus 16
structure length 95
sequence length 96
chains with identical sequence B
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2008-12-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17820 PDZ_6 PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 2w7rA00
2KJDA 1TP5A 1V5LA 3NGHA 2DM8A 2DMZA 1P1EA 3KZDA 3QJNA 5GLJA 2FN5A 5HFCA 2LUIA 3QIKA 1T2MA 3ZRTA 1TQ3A 1YBOA 5EYZA 2G5MB 5EZ0A 2D92A 3ID1A 2V90A 4NXQA 4K75A 2ENOA 1IU2A 1TE0A 1U39A 3SHUA 3GSLA 1Z87A 5HFDA 1X45A 1P1DA 4R2ZA 3TSZA 2YT8A 5FB8C 2EDPA 2OMJA 2Q3GA 2DLSA 2EXGA 1Y7NA 1VJ6A 3MH4A 2MHOA 2D8IA 2VRFA 1RY4A 4JL7A 3GDVA 5HF4A 1VB7A 2IWPA 2DJTA 2FCFA 4OEOA 1N7EA 4JORA 3TSVA 2I4SA 4GVDA 1UJVA 3DJ3A 4OAJA 1UHPA 2PKTA 3GJ9A 1U3BA 1WH1A 1GQ5A 1W9EA 1WF7A 2KOJA 2KAWA 1UJDA 5I7ZA 2IWOA 4HOPA 3GCNA 2OGPA 1QLCA 2P3WA 2AWUA 2JREA 5F67A 3STJA 5A2PA 5HEYA 4Z33A 2M10A 1IHJA 3CH8A 5HJ1A 2OQSA 1OBZA 1XZ9A 2KJPA 2PZDA 3PV4A 1WI2A 4WYUA 5DTHA 2E7KA 2QKVA 2VSPA 3R69A 3BPUA 3R68A 3DJ1A 2L4SA 2HGAA 2OSGA 3EGGC 2KPLA 1NTEA 3K1RA 1X5RA 1X6DA 3GGEA 2M0VA 4K78A 2EAQA 3DIWA 3GCOA 4G69A 2ZPMA 2R3YA 4JOJA 2M0TA 4K76A 3ID3A 2KJKA 2EEGA 2I0IA 2H2CA 2LOBA 3PV5A 3SHWA 2W4FA 3SFJA 1UFXA 1FC9A 4NMRA 1OBXA 3ID4A 5E11A 2LC7A 2CSJA 2X7ZA 5G1DA 1Q3OA 2VZ5A 1UJUA 1QAUA 2KYLA 2QT5A 1WF8A 1KY9A 2AWXA 2VWRA 1GM1A 1G9OA 1QAVB 2EHRA 5HFBA 2IWQA 3NFKA 2JOAA 3GDUA 1UF1A 4Q2OA 2LC6A 4Q3HA 1V62A 1VCWA 3TMHA 4F8KA 1WFVA 3KZEA 1BFEA 3EGHC 1UEPA 2AWWA 1M5ZA 2JWEA 2KG2A 4JOPA 2QKTA 4NMTA 1N99A 4N6XA 4YDPA 1OBYA 2KPKA 2ZPLA 2DAZA 2R4HA 2DLUA 4REYA 2FNEA 2EJYA 3QO6A 2V1WA 4RI0A 1N6EA 2PA1A 3PV2A 2Q9VA 2H3LA 2JIKA 2L4TA 1V5QA 2AINA 2W7RA 2EEHA 4UU5A 1B8QA 5D13A 4MPAA 2F0AA 1IU0A 2OS6A 3O46A 4WYTA 2CS5A 5FHTA 2KA9A 2CSSA 5GNDA 4YYXA 3OTPA 3MH6A 2D90A 2JXOA 2OZFA 3I18A 2H2BA 2WL7A 4NXRA 2F5YA 2M0ZA 4GVCA 1MC7A 2PKUA 3VQGA 2DB5A 1NF3C 2IWNA 3LNXA 3QJMA 4O06A 5H3JA 4LMMA 1KWAA 2G2LA 4GHNA 3PS4A 4Q6SA 1Z86A 1BE9A 4L8NA 2LA8A 4NMSA 4Z8JA 1WI4A 3RLEA 2BYGA 1SOTA 1ZOKA 3SOEA 3R0HA 1WIFA 4PQWA 1VAEA 1RGWA 2QBWA 3CS0A 1W9OA 4E34A 2KRGA 4NNLA 2FE5A 2OPGA 4NMQA 5E22A 1V6BA 2QG1A 4HOPB 3PDZA 1I16A 1ZUBA 1L6OA 2VSVA 2K20A 2Z9IA 1I92A 1W9QA 2EGOA 2JINA 2DKRA 2PNTA 3K50A 2I04A 3QGLA 1K32A 2EEIA 3OU0A 1GQ4A 2UZCA 3JXTA 3QDOA 3RL8A 1N7FA 2HE2A 4Q2QA 5F3XA 3AXAA 2KL1A 1U38A 4JOKA 3TSWA 1FC7A 3DJAA 5E21A 5JXBA 2YTWA 4H11A 2K1ZA 1D5GA 2L97A 4XHVA 3KHFA 1Q7XA 1FCFA 1WFGA 3GDSA 4UU6A 3FY5A 3MH7A 4K72A 4NMOA 1OZIA 4JOFA 5HEDA 2O2TA 3HVQC 3NFLA 1X8SA 4OEPA 3I4WA 1N6FA 2YUBA 2KOMA 3WKMA 4E35A 1UITA 2EEJA 4FGMA 2PDZA 1PDRA 4NXPA 1X5NA 1U37A 4EDJA 5B6LA 1UM7A 2EGNA 2MX6A 1V1TA 1UEQA 2QKUA 2GZVA 3HPKA 1UEZA 2M3MA 3SUZA 1R6JA 1RZXA 4K6YA 1RGRA 4KFVA 1UM1A 1WHAA 3VQFA 4AMHA 3DORA 2KBSA 4NNMA 4Q2PA 3CBZA 2JILA 5E1YA 3CC0A 4JOGA 3LNYA 1WHDA 4P0CA 4JOHA 1KEFA 2Z17A 1Q3PA 1VA8A 2KQFA 1SOZA 2I6VA 1X5QA 1LCYA 3HPMA 3RL7A 1Y8TA 2I0LA 5HETA 1N7TA 1WJLA 2REYA 2EDZA 3CBYA 5G1EA 5E6PB 1UEWA 2H3MA 2M0UA 3ID2A 2VPHA 4IC6A 2EDVA 3CBXA 5HDYA 5HEBA 2I1NA 3QE1A 1QAVA 2YT7A 4NMPA 3CYYA 3WKLA 3B76A 3L4FD 5HFFA 4NMVA 3K82A 2HE4A 2KOHA 2RCZA 5HF1A 4JOEA 3O5NA 2EGKA 4P2AB 1N6DA 4E3BA 3PDVA 1MFLA 1TP3A 2YUYA 1MFGA 4KFWA 1FC6A 4Q6HA 2DC2A 3E17A 3I1EA 4Q2NA 1WG6A 2OCSA 2EV8A 2KV8A 5HFEA 2RRMA
chains in the Genus database with same CATH superfamily
2KJDA 1TP5A 1V5LA 3NGHA 2DM8A 2DMZA 1P1EA 2GEFA 3KZDA 3QJNA 5GLJA 2FN5A 5HFCA 2LUIA 3QIKA 1T2MA 3ZRTA 1TQ3A 1YBOA 5EYZA 2G5MB 5EZ0A 2D92A 3ID1A 2V90A 4NXQA 4K75A 2ENOA 1IU2A 1TE0A 1U39A 3SHUA 3GSLA 1Z87A 5HFDA 1X45A 1P1DA 4R2ZA 3TSZA 2YT8A 5FB8C 5B42A 2EDPA 2OMJA 2Q3GA 2DLSA 2EXGA 1Y7NA 1VJ6A 3MH4A 2MHOA 2D8IA 2VRFA 1RY4A 4JL7A 3GDVA 5HF4A 1VB7A 2IWPA 2DJTA 2FCFA 4OEOA 1N7EA 4JORA 3TSVA 2I4SA 4GVDA 1UJVA 3DJ3A 4OAJA 1UHPA 2PKTA 3GJ9A 1U3BA 1WH1A 1GQ5A 1W9EA 4JJ0A 1WF7A 2KOJA 2KAWA 1UJDA 5I7ZA 2IWOA 4HOPA 3GCNA 2OGPA 1QLCA 2P3WA 2AWUA 2JREA 5F67A 3STJA 5A2PA 5HEYA 4Z33A 2M10A 1IHJA 3CH8A 5HJ1A 2OQSA 1OBZA 1XZ9A 2KJPA 2PZDA 3PV4A 1WI2A 4WYUA 5DTHA 2E7KA 2QKVA 2VSPA 3R69A 3BPUA 3R68A 3DJ1A 2L4SA 2HGAA 2OSGA 3EGGC 2KPLA 1NTEA 3K1RA 1X5RA 1X6DA 3GGEA 2M0VA 4K78A 2EAQA 3DIWA 3GCOA 4G69A 2ZPMA 2R3YA 4JOJA 2M0TA 4K76A 3ID3A 2KJKA 2EEGA 2I0IA 2H2CA 2LOBA 3PV5A 3SHWA 2W4FA 3SFJA 1UFXA 1FC9A 4NMRA 1OBXA 3ID4A 5E11A 2LC7A 2CSJA 2X7ZA 5G1DA 1Q3OA 2VZ5A 1UJUA 1QAUA 2KYLA 2QT5A 1WF8A 1KY9A 2AWXA 2VWRA 1GM1A 1G9OA 1QAVB 2EHRA 5HFBA 2IWQA 3NFKA 2JOAA 3GDUA 1UF1A 4Q2OA 2LC6A 4Q3HA 1V62A 1VCWA 3TMHA 4F8KA 1WFVA 3KZEA 1BFEA 3EGHC 1UEPA 2AWWA 1M5ZA 2JWEA 2KG2A 4JOPA 2QKTA 4NMTA 1N99A 4N6XA 4YDPA 1OBYA 2KPKA 2ZPLA 2DAZA 2R4HA 2DLUA 4REYA 3GABA 2FNEA 2EJYA 3KDGA 3QO6A 2V1WA 4RI0A 1N6EA 2PA1A 3PV2A 2Q9VA 2H3LA 2JIKA 2L4TA 1V5QA 2AINA 2W7RA 2EEHA 4UU5A 1B8QA 5D13A 4MPAA 2F0AA 1IU0A 2OS6A 3O46A 5ILBA 4WYTA 2CS5A 5FHTA 2KA9A 2CSSA 5GNDA 4YYXA 3OTPA 3MH6A 2D90A 2JXOA 2OZFA 3I18A 2H2BA 2WL7A 4NXRA 2F5YA 2M0ZA 4GVCA 1MC7A 2PKUA 3VQGA 2DB5A 1NF3C 2IWNA 3LNXA 3QJMA 4O06A 5H3JA 4LMMA 1KWAA 2G2LA 4GHNA 3PS4A 4Q6SA 1Z86A 1BE9A 4L8NA 2LA8A 4NMSA 1X9ZA 4Z8JA 1WI4A 3RLEA 2BYGA 1SOTA 1ZOKA 3SOEA 3R0HA 1WIFA 4PQWA 1VAEA 1RGWA 2QBWA 3CS0A 1W9OA 4JJ3A 4E34A 2KRGA 4NNLA 2FE5A 2OPGA 4NMQA 5E22A 1V6BA 2QG1A 4HOPB 3PDZA 1I16A 1ZUBA 1L6OA 2VSVA 2K20A 2Z9IA 1I92A 1W9QA 2EGOA 2JINA 2DKRA 2PNTA 3K50A 2I04A 3QGLA 1K32A 2EEIA 3OU0A 1GQ4A 2UZCA 3NCVA 3JXTA 3QDOA 3RL8A 1N7FA 2HE2A 4Q2QA 5F3XA 3AXAA 2KL1A 1U38A 4JOKA 3TSWA 1FC7A 3DJAA 5E21A 5JXBA 2YTWA 4H11A 2K1ZA 1D5GA 2L97A 4XHVA 3KHFA 1Q7XA 1FCFA 1WFGA 3GDSA 4UU6A 3FY5A 3MH7A 4K72A 4NMOA 1OZIA 4JOFA 5HEDA 2O2TA 3HVQC 3NFLA 1X8SA 4OEPA 3I4WA 1N6FA 2YUBA 2KOMA 3WKMA 4E35A 1UITA 2EEJA 4FGMA 2PDZA 1PDRA 2JSNA 4NXPA 1X5NA 1U37A 4EDJA 5B6LA 1UM7A 2EGNA 2MX6A 1V1TA 1UEQA 2QKUA 2GZVA 3HPKA 1UEZA 2M3MA 3SUZA 1R6JA 1RZXA 4K6YA 1RGRA 4KFVA 1UM1A 1WHAA 3VQFA 4AMHA 3DORA 5IL9A 2KBSA 4NNMA 4Q2PA 3CBZA 2JILA 5E1YA 3CC0A 4JOGA 3LNYA 1WHDA 4P0CA 4JOHA 1KEFA 2Z17A 3KDKA 1Q3PA 1VA8A 2KQFA 1SOZA 2I6VA 1X5QA 1LCYA 3HPMA 3RL7A 1Y8TA 2I0LA 5HETA 1N7TA 1WJLA 2REYA 2EDZA 3CBYA 5G1EA 5E6PB 1UEWA 2H3MA 2M0UA 3ID2A 2VPHA 4IC6A 2EDVA 3CBXA 5HDYA 5HEBA 2I1NA 3QE1A 1QAVA 2YT7A 4NMPA 3CYYA 3WKLA 3B76A 3L4FD 5HFFA 4NMVA 3K82A 2HE4A 2KOHA 2RCZA 5HF1A 4JOEA 3O5NA 2EGKA 4FLNA 4P2AB 1N6DA 4E3BA 3PDVA 1MFLA 1TP3A 2YUYA 1MFGA 4KFWA 1FC6A 4Q6HA 2DC2A 3E17A 3I1EA 4Q2NA 1WG6A 2OCSA 2EV8A 2KV8A 5HFEA 2RRMA
chains in the Genus database with same CATH topology
2KJDA 1TP5A 1V5LA 3NGHA 2DM8A 2DMZA 1P1EA 2GEFA 3KZDA 3QJNA 5GLJA 2FN5A 5HFCA 2LUIA 3QIKA 1T2MA 3ZRTA 1TQ3A 1YBOA 5EYZA 2G5MB 5EZ0A 2D92A 3ID1A 2V90A 4NXQA 4K75A 2ENOA 1IU2A 1TE0A 1U39A 3SHUA 3GSLA 1Z87A 5HFDA 1X45A 1P1DA 4R2ZA 3TSZA 2YT8A 5FB8C 5B42A 2EDPA 2OMJA 2Q3GA 2DLSA 2EXGA 1Y7NA 1VJ6A 3MH4A 2MHOA 2D8IA 2VRFA 1RY4A 4JL7A 3GDVA 5HF4A 1VB7A 2IWPA 2DJTA 2FCFA 4OEOA 1N7EA 4JORA 3TSVA 2I4SA 4GVDA 1UJVA 3DJ3A 4OAJA 1UHPA 2PKTA 3GJ9A 1U3BA 1WH1A 1GQ5A 1W9EA 4JJ0A 1WF7A 2KOJA 2KAWA 1UJDA 5I7ZA 2IWOA 4HOPA 3GCNA 2OGPA 1QLCA 2P3WA 2AWUA 2JREA 5F67A 3STJA 5A2PA 5HEYA 4Z33A 2M10A 1IHJA 3CH8A 5HJ1A 2OQSA 1OBZA 1XZ9A 2KJPA 2PZDA 3PV4A 1WI2A 4WYUA 5DTHA 2E7KA 2QKVA 2VSPA 3R69A 3BPUA 3R68A 3DJ1A 2L4SA 2HGAA 2OSGA 3EGGC 2KPLA 1NTEA 3K1RA 1X5RA 1X6DA 3GGEA 2M0VA 4K78A 2EAQA 3DIWA 3GCOA 4G69A 2ZPMA 2R3YA 4JOJA 2M0TA 4K76A 3ID3A 2KJKA 2EEGA 2I0IA 2H2CA 2LOBA 3PV5A 3SHWA 2W4FA 3SFJA 1UFXA 1FC9A 4NMRA 1OBXA 3ID4A 5E11A 2LC7A 2CSJA 2X7ZA 5G1DA 1Q3OA 2VZ5A 1UJUA 1QAUA 2KYLA 2QT5A 1WF8A 1KY9A 2AWXA 2VWRA 1GM1A 1G9OA 1QAVB 2EHRA 5HFBA 2IWQA 3NFKA 2JOAA 3GDUA 1UF1A 4Q2OA 2LC6A 4Q3HA 1V62A 1VCWA 3TMHA 4F8KA 1WFVA 3KZEA 1BFEA 3EGHC 1UEPA 2AWWA 1M5ZA 2JWEA 2KG2A 4JOPA 2QKTA 4NMTA 1N99A 4N6XA 4YDPA 1OBYA 2KPKA 2ZPLA 2DAZA 2R4HA 2DLUA 4REYA 3GABA 2FNEA 2EJYA 3KDGA 3QO6A 2V1WA 4RI0A 1N6EA 2PA1A 3PV2A 2Q9VA 2H3LA 2JIKA 2L4TA 1V5QA 2AINA 2W7RA 2EEHA 4UU5A 1B8QA 5D13A 4MPAA 2F0AA 1IU0A 2OS6A 3O46A 5ILBA 4WYTA 2CS5A 5FHTA 2KA9A 2CSSA 5GNDA 4YYXA 3OTPA 3MH6A 2D90A 2JXOA 2OZFA 3I18A 2H2BA 2WL7A 4NXRA 2F5YA 2M0ZA 4GVCA 1MC7A 2PKUA 3VQGA 2DB5A 1NF3C 2IWNA 3LNXA 3QJMA 4O06A 5H3JA 4LMMA 1KWAA 2G2LA 4GHNA 3PS4A 4Q6SA 1Z86A 1BE9A 4L8NA 2LA8A 4NMSA 1X9ZA 4Z8JA 1WI4A 3RLEA 2BYGA 1SOTA 1ZOKA 3SOEA 3R0HA 1WIFA 4PQWA 1VAEA 1RGWA 2QBWA 3CS0A 1W9OA 4JJ3A 4E34A 2KRGA 4NNLA 2FE5A 2OPGA 4NMQA 5E22A 1V6BA 2QG1A 4HOPB 3PDZA 1I16A 1ZUBA 1L6OA 2VSVA 2K20A 2Z9IA 1I92A 1W9QA 2EGOA 2JINA 2DKRA 2PNTA 3K50A 2I04A 3QGLA 1K32A 2EEIA 3OU0A 1GQ4A 2UZCA 3NCVA 3JXTA 3QDOA 3RL8A 1N7FA 2HE2A 4Q2QA 5F3XA 3AXAA 2KL1A 1U38A 4JOKA 3TSWA 1FC7A 3DJAA 5E21A 5JXBA 2YTWA 4H11A 2K1ZA 1D5GA 2L97A 4XHVA 3KHFA 1Q7XA 1FCFA 1WFGA 3GDSA 4UU6A 3FY5A 3MH7A 4K72A 4NMOA 1OZIA 4JOFA 5HEDA 2O2TA 3HVQC 3NFLA 1X8SA 4OEPA 3I4WA 1N6FA 2YUBA 2KOMA 3WKMA 4E35A 1UITA 2EEJA 4FGMA 2PDZA 1PDRA 2JSNA 4NXPA 1X5NA 1U37A 4EDJA 5B6LA 1UM7A 2EGNA 2MX6A 1V1TA 1UEQA 2QKUA 2GZVA 3HPKA 1UEZA 2M3MA 3SUZA 1R6JA 1RZXA 4K6YA 1RGRA 4KFVA 1UM1A 1WHAA 3VQFA 4AMHA 3DORA 5IL9A 2KBSA 4NNMA 4Q2PA 3CBZA 2JILA 5E1YA 3CC0A 4JOGA 3LNYA 1WHDA 4P0CA 4JOHA 1KEFA 2Z17A 3KDKA 1Q3PA 1VA8A 2KQFA 1SOZA 2I6VA 1X5QA 1LCYA 3HPMA 3RL7A 1Y8TA 2I0LA 5HETA 1N7TA 1WJLA 2REYA 2EDZA 3CBYA 5G1EA 5E6PB 1UEWA 2H3MA 2M0UA 3ID2A 2VPHA 4IC6A 2EDVA 3CBXA 5HDYA 5HEBA 2I1NA 3QE1A 1QAVA 2YT7A 4NMPA 3CYYA 3WKLA 3B76A 3L4FD 5HFFA 4NMVA 3K82A 2HE4A 2KOHA 2RCZA 5HF1A 4JOEA 3O5NA 2EGKA 4FLNA 4P2AB 1N6DA 4E3BA 3PDVA 1MFLA 1TP3A 2YUYA 1MFGA 4KFWA 1FC6A 4Q6HA 2DC2A 3E17A 3I1EA 4Q2NA 1WG6A 2OCSA 2EV8A 2KV8A 5HFEA 2RRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KJD A;  1TP5 A;  1V5L A;  3NGH A;  2DM8 A;  2DMZ A;  1P1E A;  3KZD A;  3QJN A;  5GLJ A;  2FN5 A;  5HFC A;  2LUI A;  3QIK A;  1T2M A;  3ZRT A;  1TQ3 A;  1YBO A;  5EYZ A;  2G5M B;  5EZ0 A;  2D92 A;  3ID1 A;  2V90 A;  4NXQ A;  4K75 A;  2ENO A;  1IU2 A;  1TE0 A;  1U39 A;  3SHU A;  3GSL A;  1Z87 A;  5HFD A;  1X45 A;  1P1D A;  4R2Z A;  3TSZ A;  2YT8 A;  5FB8 C;  2EDP A;  2OMJ A;  2Q3G A;  2DLS A;  2EXG A;  1Y7N A;  1VJ6 A;  3MH4 A;  2MHO A;  2D8I A;  2VRF A;  1RY4 A;  4JL7 A;  3GDV A;  5HF4 A;  1VB7 A;  2IWP A;  2DJT A;  2FCF A;  4OEO A;  1N7E A;  4JOR A;  3TSV A;  2I4S A;  4GVD A;  1UJV A;  3DJ3 A;  4OAJ A;  1UHP A;  2PKT A;  3GJ9 A;  1U3B A;  1WH1 A;  1GQ5 A;  1W9E A;  1WF7 A;  2KOJ A;  2KAW A;  1UJD A;  5I7Z A;  2IWO A;  4HOP A;  3GCN A;  2OGP A;  1QLC A;  2P3W A;  2AWU A;  2JRE A;  5F67 A;  3STJ A;  5A2P A;  5HEY A;  4Z33 A;  2M10 A;  1IHJ A;  3CH8 A;  5HJ1 A;  2OQS A;  1OBZ A;  1XZ9 A;  2KJP A;  2PZD A;  3PV4 A;  1WI2 A;  4WYU A;  5DTH A;  2E7K A;  2QKV A;  2VSP A;  3R69 A;  3BPU A;  3R68 A;  3DJ1 A;  2L4S A;  2HGA A;  2OSG A;  3EGG C;  2KPL A;  1NTE A;  3K1R A;  1X5R A;  1X6D A;  3GGE A;  2M0V A;  4K78 A;  2EAQ A;  3DIW A;  3GCO A;  4G69 A;  2ZPM A;  2R3Y A;  4JOJ A;  2M0T A;  4K76 A;  3ID3 A;  2KJK A;  2EEG A;  2I0I A;  2H2C A;  2LOB A;  3PV5 A;  3SHW A;  2W4F A;  3SFJ A;  1UFX A;  1FC9 A;  4NMR A;  1OBX A;  3ID4 A;  5E11 A;  2LC7 A;  2CSJ A;  2X7Z A;  5G1D A;  1Q3O A;  2VZ5 A;  1UJU A;  1QAU A;  2KYL A;  2QT5 A;  1WF8 A;  1KY9 A;  2AWX A;  2VWR A;  1GM1 A;  1G9O A;  1QAV B;  2EHR A;  5HFB A;  2IWQ A;  3NFK A;  2JOA A;  3GDU A;  1UF1 A;  4Q2O A;  2LC6 A;  4Q3H A;  1V62 A;  1VCW A;  3TMH A;  4F8K A;  1WFV A;  3KZE A;  1BFE A;  3EGH C;  1UEP A;  2AWW A;  1M5Z A;  2JWE A;  2KG2 A;  4JOP A;  2QKT A;  4NMT A;  1N99 A;  4N6X A;  4YDP A;  1OBY A;  2KPK A;  2ZPL A;  2DAZ A;  2R4H A;  2DLU A;  4REY A;  2FNE A;  2EJY A;  3QO6 A;  2V1W A;  4RI0 A;  1N6E A;  2PA1 A;  3PV2 A;  2Q9V A;  2H3L A;  2JIK A;  2L4T A;  1V5Q A;  2AIN A;  2W7R A;  2EEH A;  4UU5 A;  1B8Q A;  5D13 A;  4MPA A;  2F0A A;  1IU0 A;  2OS6 A;  3O46 A;  4WYT A;  2CS5 A;  5FHT A;  2KA9 A;  2CSS A;  5GND A;  4YYX A;  3OTP A;  3MH6 A;  2D90 A;  2JXO A;  2OZF A;  3I18 A;  2H2B A;  2WL7 A;  4NXR A;  2F5Y A;  2M0Z A;  4GVC A;  1MC7 A;  2PKU A;  3VQG A;  2DB5 A;  1NF3 C;  2IWN A;  3LNX A;  3QJM A;  4O06 A;  5H3J A;  4LMM A;  1KWA A;  2G2L A;  4GHN A;  3PS4 A;  4Q6S A;  1Z86 A;  1BE9 A;  4L8N A;  2LA8 A;  4NMS A;  4Z8J A;  1WI4 A;  3RLE A;  2BYG A;  1SOT A;  1ZOK A;  3SOE A;  3R0H A;  1WIF A;  4PQW A;  1VAE A;  1RGW A;  2QBW A;  3CS0 A;  1W9O A;  4E34 A;  2KRG A;  4NNL A;  2FE5 A;  2OPG A;  4NMQ A;  5E22 A;  1V6B A;  2QG1 A;  4HOP B;  3PDZ A;  1I16 A;  1ZUB A;  1L6O A;  2VSV A;  2K20 A;  2Z9I A;  1I92 A;  1W9Q A;  2EGO A;  2JIN A;  2DKR A;  2PNT A;  3K50 A;  2I04 A;  3QGL A;  1K32 A;  2EEI A;  3OU0 A;  1GQ4 A;  2UZC A;  3JXT A;  3QDO A;  3RL8 A;  1N7F A;  2HE2 A;  4Q2Q A;  5F3X A;  3AXA A;  2KL1 A;  1U38 A;  4JOK A;  3TSW A;  1FC7 A;  3DJA A;  5E21 A;  5JXB A;  2YTW A;  4H11 A;  2K1Z A;  1D5G A;  2L97 A;  4XHV A;  3KHF A;  1Q7X A;  1FCF A;  1WFG A;  3GDS A;  4UU6 A;  3FY5 A;  3MH7 A;  4K72 A;  4NMO A;  1OZI A;  4JOF A;  5HED A;  2O2T A;  3HVQ C;  3NFL A;  1X8S A;  4OEP A;  3I4W A;  1N6F A;  2YUB A;  2KOM A;  3WKM A;  4E35 A;  1UIT A;  2EEJ A;  4FGM A;  2PDZ A;  1PDR A;  4NXP A;  1X5N A;  1U37 A;  4EDJ A;  5B6L A;  1UM7 A;  2EGN A;  2MX6 A;  1V1T A;  1UEQ A;  2QKU A;  2GZV A;  3HPK A;  1UEZ A;  2M3M A;  3SUZ A;  1R6J A;  1RZX A;  4K6Y A;  1RGR A;  4KFV A;  1UM1 A;  1WHA A;  3VQF A;  4AMH A;  3DOR A;  2KBS A;  4NNM A;  4Q2P A;  3CBZ A;  2JIL A;  5E1Y A;  3CC0 A;  4JOG A;  3LNY A;  1WHD A;  4P0C A;  4JOH A;  1KEF A;  2Z17 A;  1Q3P A;  1VA8 A;  2KQF A;  1SOZ A;  2I6V A;  1X5Q A;  1LCY A;  3HPM A;  3RL7 A;  1Y8T A;  2I0L A;  5HET A;  1N7T A;  1WJL A;  2REY A;  2EDZ A;  3CBY A;  5G1E A;  5E6P B;  1UEW A;  2H3M A;  2M0U A;  3ID2 A;  2VPH A;  4IC6 A;  2EDV A;  3CBX A;  5HDY A;  5HEB A;  2I1N A;  3QE1 A;  1QAV A;  2YT7 A;  4NMP A;  3CYY A;  3WKL A;  3B76 A;  3L4F D;  5HFF A;  4NMV A;  3K82 A;  2HE4 A;  2KOH A;  2RCZ A;  5HF1 A;  4JOE A;  3O5N A;  2EGK A;  4P2A B;  1N6D A;  4E3B A;  3PDV A;  1MFL A;  1TP3 A;  2YUY A;  1MFG A;  4KFW A;  1FC6 A;  4Q6H A;  2DC2 A;  3E17 A;  3I1E A;  4Q2N A;  1WG6 A;  2OCS A;  2EV8 A;  2KV8 A;  5HFE A;  2RRM A; 
#chains in the Genus database with same CATH topology
 2KJD A;  1TP5 A;  1V5L A;  3NGH A;  2DM8 A;  2DMZ A;  1P1E A;  2GEF A;  3KZD A;  3QJN A;  5GLJ A;  2FN5 A;  5HFC A;  2LUI A;  3QIK A;  1T2M A;  3ZRT A;  1TQ3 A;  1YBO A;  5EYZ A;  2G5M B;  5EZ0 A;  2D92 A;  3ID1 A;  2V90 A;  4NXQ A;  4K75 A;  2ENO A;  1IU2 A;  1TE0 A;  1U39 A;  3SHU A;  3GSL A;  1Z87 A;  5HFD A;  1X45 A;  1P1D A;  4R2Z A;  3TSZ A;  2YT8 A;  5FB8 C;  5B42 A;  2EDP A;  2OMJ A;  2Q3G A;  2DLS A;  2EXG A;  1Y7N A;  1VJ6 A;  3MH4 A;  2MHO A;  2D8I A;  2VRF A;  1RY4 A;  4JL7 A;  3GDV A;  5HF4 A;  1VB7 A;  2IWP A;  2DJT A;  2FCF A;  4OEO A;  1N7E A;  4JOR A;  3TSV A;  2I4S A;  4GVD A;  1UJV A;  3DJ3 A;  4OAJ A;  1UHP A;  2PKT A;  3GJ9 A;  1U3B A;  1WH1 A;  1GQ5 A;  1W9E A;  4JJ0 A;  1WF7 A;  2KOJ A;  2KAW A;  1UJD A;  5I7Z A;  2IWO A;  4HOP A;  3GCN A;  2OGP A;  1QLC A;  2P3W A;  2AWU A;  2JRE A;  5F67 A;  3STJ A;  5A2P A;  5HEY A;  4Z33 A;  2M10 A;  1IHJ A;  3CH8 A;  5HJ1 A;  2OQS A;  1OBZ A;  1XZ9 A;  2KJP A;  2PZD A;  3PV4 A;  1WI2 A;  4WYU A;  5DTH A;  2E7K A;  2QKV A;  2VSP A;  3R69 A;  3BPU A;  3R68 A;  3DJ1 A;  2L4S A;  2HGA A;  2OSG A;  3EGG C;  2KPL A;  1NTE A;  3K1R A;  1X5R A;  1X6D A;  3GGE A;  2M0V A;  4K78 A;  2EAQ A;  3DIW A;  3GCO A;  4G69 A;  2ZPM A;  2R3Y A;  4JOJ A;  2M0T A;  4K76 A;  3ID3 A;  2KJK A;  2EEG A;  2I0I A;  2H2C A;  2LOB A;  3PV5 A;  3SHW A;  2W4F A;  3SFJ A;  1UFX A;  1FC9 A;  4NMR A;  1OBX A;  3ID4 A;  5E11 A;  2LC7 A;  2CSJ A;  2X7Z A;  5G1D A;  1Q3O A;  2VZ5 A;  1UJU A;  1QAU A;  2KYL A;  2QT5 A;  1WF8 A;  1KY9 A;  2AWX A;  2VWR A;  1GM1 A;  1G9O A;  1QAV B;  2EHR A;  5HFB A;  2IWQ A;  3NFK A;  2JOA A;  3GDU A;  1UF1 A;  4Q2O A;  2LC6 A;  4Q3H A;  1V62 A;  1VCW A;  3TMH A;  4F8K A;  1WFV A;  3KZE A;  1BFE A;  3EGH C;  1UEP A;  2AWW A;  1M5Z A;  2JWE A;  2KG2 A;  4JOP A;  2QKT A;  4NMT A;  1N99 A;  4N6X A;  4YDP A;  1OBY A;  2KPK A;  2ZPL A;  2DAZ A;  2R4H A;  2DLU A;  4REY A;  3GAB A;  2FNE A;  2EJY A;  3KDG A;  3QO6 A;  2V1W A;  4RI0 A;  1N6E A;  2PA1 A;  3PV2 A;  2Q9V A;  2H3L A;  2JIK A;  2L4T A;  1V5Q A;  2AIN A;  2W7R A;  2EEH A;  4UU5 A;  1B8Q A;  5D13 A;  4MPA A;  2F0A A;  1IU0 A;  2OS6 A;  3O46 A;  5ILB A;  4WYT A;  2CS5 A;  5FHT A;  2KA9 A;  2CSS A;  5GND A;  4YYX A;  3OTP A;  3MH6 A;  2D90 A;  2JXO A;  2OZF A;  3I18 A;  2H2B A;  2WL7 A;  4NXR A;  2F5Y A;  2M0Z A;  4GVC A;  1MC7 A;  2PKU A;  3VQG A;  2DB5 A;  1NF3 C;  2IWN A;  3LNX A;  3QJM A;  4O06 A;  5H3J A;  4LMM A;  1KWA A;  2G2L A;  4GHN A;  3PS4 A;  4Q6S A;  1Z86 A;  1BE9 A;  4L8N A;  2LA8 A;  4NMS A;  1X9Z A;  4Z8J A;  1WI4 A;  3RLE A;  2BYG A;  1SOT A;  1ZOK A;  3SOE A;  3R0H A;  1WIF A;  4PQW A;  1VAE A;  1RGW A;  2QBW A;  3CS0 A;  1W9O A;  4JJ3 A;  4E34 A;  2KRG A;  4NNL A;  2FE5 A;  2OPG A;  4NMQ A;  5E22 A;  1V6B A;  2QG1 A;  4HOP B;  3PDZ A;  1I16 A;  1ZUB A;  1L6O A;  2VSV A;  2K20 A;  2Z9I A;  1I92 A;  1W9Q A;  2EGO A;  2JIN A;  2DKR A;  2PNT A;  3K50 A;  2I04 A;  3QGL A;  1K32 A;  2EEI A;  3OU0 A;  1GQ4 A;  2UZC A;  3NCV A;  3JXT A;  3QDO A;  3RL8 A;  1N7F A;  2HE2 A;  4Q2Q A;  5F3X A;  3AXA A;  2KL1 A;  1U38 A;  4JOK A;  3TSW A;  1FC7 A;  3DJA A;  5E21 A;  5JXB A;  2YTW A;  4H11 A;  2K1Z A;  1D5G A;  2L97 A;  4XHV A;  3KHF A;  1Q7X A;  1FCF A;  1WFG A;  3GDS A;  4UU6 A;  3FY5 A;  3MH7 A;  4K72 A;  4NMO A;  1OZI A;  4JOF A;  5HED A;  2O2T A;  3HVQ C;  3NFL A;  1X8S A;  4OEP A;  3I4W A;  1N6F A;  2YUB A;  2KOM A;  3WKM A;  4E35 A;  1UIT A;  2EEJ A;  4FGM A;  2PDZ A;  1PDR A;  2JSN A;  4NXP A;  1X5N A;  1U37 A;  4EDJ A;  5B6L A;  1UM7 A;  2EGN A;  2MX6 A;  1V1T A;  1UEQ A;  2QKU A;  2GZV A;  3HPK A;  1UEZ A;  2M3M A;  3SUZ A;  1R6J A;  1RZX A;  4K6Y A;  1RGR A;  4KFV A;  1UM1 A;  1WHA A;  3VQF A;  4AMH A;  3DOR A;  5IL9 A;  2KBS A;  4NNM A;  4Q2P A;  3CBZ A;  2JIL A;  5E1Y A;  3CC0 A;  4JOG A;  3LNY A;  1WHD A;  4P0C A;  4JOH A;  1KEF A;  2Z17 A;  3KDK A;  1Q3P A;  1VA8 A;  2KQF A;  1SOZ A;  2I6V A;  1X5Q A;  1LCY A;  3HPM A;  3RL7 A;  1Y8T A;  2I0L A;  5HET A;  1N7T A;  1WJL A;  2REY A;  2EDZ A;  3CBY A;  5G1E A;  5E6P B;  1UEW A;  2H3M A;  2M0U A;  3ID2 A;  2VPH A;  4IC6 A;  2EDV A;  3CBX A;  5HDY A;  5HEB A;  2I1N A;  3QE1 A;  1QAV A;  2YT7 A;  4NMP A;  3CYY A;  3WKL A;  3B76 A;  3L4F D;  5HFF A;  4NMV A;  3K82 A;  2HE4 A;  2KOH A;  2RCZ A;  5HF1 A;  4JOE A;  3O5N A;  2EGK A;  4FLN A;  4P2A B;  1N6D A;  4E3B A;  3PDV A;  1MFL A;  1TP3 A;  2YUY A;  1MFG A;  4KFW A;  1FC6 A;  4Q6H A;  2DC2 A;  3E17 A;  3I1E A;  4Q2N A;  1WG6 A;  2OCS A;  2EV8 A;  2KV8 A;  5HFE A;  2RRM A; 
#chains in the Genus database with same CATH homology
 2KJD A;  1TP5 A;  1V5L A;  3NGH A;  2DM8 A;  2DMZ A;  1P1E A;  2GEF A;  3KZD A;  3QJN A;  5GLJ A;  2FN5 A;  5HFC A;  2LUI A;  3QIK A;  1T2M A;  3ZRT A;  1TQ3 A;  1YBO A;  5EYZ A;  2G5M B;  5EZ0 A;  2D92 A;  3ID1 A;  2V90 A;  4NXQ A;  4K75 A;  2ENO A;  1IU2 A;  1TE0 A;  1U39 A;  3SHU A;  3GSL A;  1Z87 A;  5HFD A;  1X45 A;  1P1D A;  4R2Z A;  3TSZ A;  2YT8 A;  5FB8 C;  5B42 A;  2EDP A;  2OMJ A;  2Q3G A;  2DLS A;  2EXG A;  1Y7N A;  1VJ6 A;  3MH4 A;  2MHO A;  2D8I A;  2VRF A;  1RY4 A;  4JL7 A;  3GDV A;  5HF4 A;  1VB7 A;  2IWP A;  2DJT A;  2FCF A;  4OEO A;  1N7E A;  4JOR A;  3TSV A;  2I4S A;  4GVD A;  1UJV A;  3DJ3 A;  4OAJ A;  1UHP A;  2PKT A;  3GJ9 A;  1U3B A;  1WH1 A;  1GQ5 A;  1W9E A;  4JJ0 A;  1WF7 A;  2KOJ A;  2KAW A;  1UJD A;  5I7Z A;  2IWO A;  4HOP A;  3GCN A;  2OGP A;  1QLC A;  2P3W A;  2AWU A;  2JRE A;  5F67 A;  3STJ A;  5A2P A;  5HEY A;  4Z33 A;  2M10 A;  1IHJ A;  3CH8 A;  5HJ1 A;  2OQS A;  1OBZ A;  1XZ9 A;  2KJP A;  2PZD A;  3PV4 A;  1WI2 A;  4WYU A;  5DTH A;  2E7K A;  2QKV A;  2VSP A;  3R69 A;  3BPU A;  3R68 A;  3DJ1 A;  2L4S A;  2HGA A;  2OSG A;  3EGG C;  2KPL A;  1NTE A;  3K1R A;  1X5R A;  1X6D A;  3GGE A;  2M0V A;  4K78 A;  2EAQ A;  3DIW A;  3GCO A;  4G69 A;  2ZPM A;  2R3Y A;  4JOJ A;  2M0T A;  4K76 A;  3ID3 A;  2KJK A;  2EEG A;  2I0I A;  2H2C A;  2LOB A;  3PV5 A;  3SHW A;  2W4F A;  3SFJ A;  1UFX A;  1FC9 A;  4NMR A;  1OBX A;  3ID4 A;  5E11 A;  2LC7 A;  2CSJ A;  2X7Z A;  5G1D A;  1Q3O A;  2VZ5 A;  1UJU A;  1QAU A;  2KYL A;  2QT5 A;  1WF8 A;  1KY9 A;  2AWX A;  2VWR A;  1GM1 A;  1G9O A;  1QAV B;  2EHR A;  5HFB A;  2IWQ A;  3NFK A;  2JOA A;  3GDU A;  1UF1 A;  4Q2O A;  2LC6 A;  4Q3H A;  1V62 A;  1VCW A;  3TMH A;  4F8K A;  1WFV A;  3KZE A;  1BFE A;  3EGH C;  1UEP A;  2AWW A;  1M5Z A;  2JWE A;  2KG2 A;  4JOP A;  2QKT A;  4NMT A;  1N99 A;  4N6X A;  4YDP A;  1OBY A;  2KPK A;  2ZPL A;  2DAZ A;  2R4H A;  2DLU A;  4REY A;  3GAB A;  2FNE A;  2EJY A;  3KDG A;  3QO6 A;  2V1W A;  4RI0 A;  1N6E A;  2PA1 A;  3PV2 A;  2Q9V A;  2H3L A;  2JIK A;  2L4T A;  1V5Q A;  2AIN A;  2W7R A;  2EEH A;  4UU5 A;  1B8Q A;  5D13 A;  4MPA A;  2F0A A;  1IU0 A;  2OS6 A;  3O46 A;  5ILB A;  4WYT A;  2CS5 A;  5FHT A;  2KA9 A;  2CSS A;  5GND A;  4YYX A;  3OTP A;  3MH6 A;  2D90 A;  2JXO A;  2OZF A;  3I18 A;  2H2B A;  2WL7 A;  4NXR A;  2F5Y A;  2M0Z A;  4GVC A;  1MC7 A;  2PKU A;  3VQG A;  2DB5 A;  1NF3 C;  2IWN A;  3LNX A;  3QJM A;  4O06 A;  5H3J A;  4LMM A;  1KWA A;  2G2L A;  4GHN A;  3PS4 A;  4Q6S A;  1Z86 A;  1BE9 A;  4L8N A;  2LA8 A;  4NMS A;  1X9Z A;  4Z8J A;  1WI4 A;  3RLE A;  2BYG A;  1SOT A;  1ZOK A;  3SOE A;  3R0H A;  1WIF A;  4PQW A;  1VAE A;  1RGW A;  2QBW A;  3CS0 A;  1W9O A;  4JJ3 A;  4E34 A;  2KRG A;  4NNL A;  2FE5 A;  2OPG A;  4NMQ A;  5E22 A;  1V6B A;  2QG1 A;  4HOP B;  3PDZ A;  1I16 A;  1ZUB A;  1L6O A;  2VSV A;  2K20 A;  2Z9I A;  1I92 A;  1W9Q A;  2EGO A;  2JIN A;  2DKR A;  2PNT A;  3K50 A;  2I04 A;  3QGL A;  1K32 A;  2EEI A;  3OU0 A;  1GQ4 A;  2UZC A;  3NCV A;  3JXT A;  3QDO A;  3RL8 A;  1N7F A;  2HE2 A;  4Q2Q A;  5F3X A;  3AXA A;  2KL1 A;  1U38 A;  4JOK A;  3TSW A;  1FC7 A;  3DJA A;  5E21 A;  5JXB A;  2YTW A;  4H11 A;  2K1Z A;  1D5G A;  2L97 A;  4XHV A;  3KHF A;  1Q7X A;  1FCF A;  1WFG A;  3GDS A;  4UU6 A;  3FY5 A;  3MH7 A;  4K72 A;  4NMO A;  1OZI A;  4JOF A;  5HED A;  2O2T A;  3HVQ C;  3NFL A;  1X8S A;  4OEP A;  3I4W A;  1N6F A;  2YUB A;  2KOM A;  3WKM A;  4E35 A;  1UIT A;  2EEJ A;  4FGM A;  2PDZ A;  1PDR A;  2JSN A;  4NXP A;  1X5N A;  1U37 A;  4EDJ A;  5B6L A;  1UM7 A;  2EGN A;  2MX6 A;  1V1T A;  1UEQ A;  2QKU A;  2GZV A;  3HPK A;  1UEZ A;  2M3M A;  3SUZ A;  1R6J A;  1RZX A;  4K6Y A;  1RGR A;  4KFV A;  1UM1 A;  1WHA A;  3VQF A;  4AMH A;  3DOR A;  5IL9 A;  2KBS A;  4NNM A;  4Q2P A;  3CBZ A;  2JIL A;  5E1Y A;  3CC0 A;  4JOG A;  3LNY A;  1WHD A;  4P0C A;  4JOH A;  1KEF A;  2Z17 A;  3KDK A;  1Q3P A;  1VA8 A;  2KQF A;  1SOZ A;  2I6V A;  1X5Q A;  1LCY A;  3HPM A;  3RL7 A;  1Y8T A;  2I0L A;  5HET A;  1N7T A;  1WJL A;  2REY A;  2EDZ A;  3CBY A;  5G1E A;  5E6P B;  1UEW A;  2H3M A;  2M0U A;  3ID2 A;  2VPH A;  4IC6 A;  2EDV A;  3CBX A;  5HDY A;  5HEB A;  2I1N A;  3QE1 A;  1QAV A;  2YT7 A;  4NMP A;  3CYY A;  3WKL A;  3B76 A;  3L4F D;  5HFF A;  4NMV A;  3K82 A;  2HE4 A;  2KOH A;  2RCZ A;  5HF1 A;  4JOE A;  3O5N A;  2EGK A;  4FLN A;  4P2A B;  1N6D A;  4E3B A;  3PDV A;  1MFL A;  1TP3 A;  2YUY A;  1MFG A;  4KFW A;  1FC6 A;  4Q6H A;  2DC2 A;  3E17 A;  3I1E A;  4Q2N A;  1WG6 A;  2OCS A;  2EV8 A;  2KV8 A;  5HFE A;  2RRM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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