2BRPA

Crystal structure of s. pneumoniae hyaluronate lyase in complex with w249b
Total Genus 254
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
pubmed doi rcsb
molecule tags Lyase
source organism Streptococcus pneumoniae
molecule keywords HYALURONATE LYASE
total genus 254
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2005-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2brpA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2brpA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2brpA02
1X1HA 3MV01 4D72A 1RW9A 1RWGA 3A0OA 1K1WA 4D6IA 1F4HA 1JYVA 1N7OA 1JZ8A 3VDBA 1NS2A 3VDAA 2WZSA 4BZEA 1NS8A 2WMFA 1HM2A 3T0BA 2WVXA 4D6JA 1HMWA 1JZ6A 1JYXA 1F4AA 1MMUA 2WW2A 1LF6A 3E7JA 2D73A 1HMUA 3DCDA 3DYPA 3AFLA 4AQ0A 1SNZA 3VDCA 1MMZA 1NSZA 1L7KA 3A24A 5JMFA 4F13A 4F10A 2Q1FA 1NSUA 1NSVA 2JKPA 3IAPA 2BRWA 1K1YA 2BRVX 1N7QA 1ULVA 3DECA 4OK4A 4D6HA 2JKAA 1PX3A 1I8QA 4E1YA 1MMXA 1LOHA 1JZ2A 2WVXB 2HTAA 4BZHA 1JZ7A 1YGAA 1UG9A 4D71A 3T2PA 3VD9A 2ZQ0A 1L7JA 1LURA 4TTGA 3K25A 2WW3A 1HV6A 2E22A 4D6EA 3I3DA 3SEPA 1PX4A 4OZVA 1HM3A 3NJVA 2WMJA 1K1XA 2E24A 1NSMA 1NSXA 3VSNA 3VD3A 1F1SA 1QAZA 1NSRA 2CISA 3VD7A 4BZGA 3WFAA 1N7PA 3ECQA 4DUWA 1LF9A 1OJMA 3MUY1 1OJNA 1JZ3A 2ZXQA 4D6DA 3T0DA 2CIRA 1X1IA 1HN1A 1TXKA 3MV11 4D6CA 2WMHA 1MN0A 1SO0A 3I3EA 3OS7A 1N7RA 2X03A 2FUTA 2WDAA 1NS0A 3DYOA 3MUZ1 4BZFA 1JYNA 1NSSA 4OZWA 3MWXA 2WMKA 1CB8A 3NFVA 3BGAA 3T2QA 1JZ5A 1DP0A 2WCOA 1W3YA 1J0MA 1J0NA 1HN0A 4MMHA 4D6FA 3VD4A 3E80A 1OJPA 3E1F1 1Z45A 3VSMA 3IAQA 3J7HA 3T09A 3Q1NA 3VD5A 1EGUA 4OJZA 1RWAA 4OK2A 1MMYA 1F9GA 4D6GA 2WMIA 1NS7A 1JYWA 1YQ2A 3I3BA 4FNVA 4MMIA 1LXKA 2CIQA 2FUQA 5JMDA 3NJXA 3OBAA 2HTBA 2WMGA 1RWCA 3T08A 2JKEA 3T0AA 1RWHA 1NS4A 2WW0A 3NREA 3OB8A 1JZ4A 3DYMA 4RNLA 1C82A 5A1AA 2XHNA 4DUVA 3IMHA 1OJOA 1JOVA 1LXMA 2XSGA 5E1QA 2BRPA 1NKGA 3CZJA 3T2OA 4DUXA 1X1JA 2WVYA 2WW1A 1N7NA 4NEIA 2WVZA 1RWFA 2WMIB 3NNBA
chains in the Genus database with same CATH superfamily
1GLMA 1RW9A 3A0OA 1HCUA 3QSPA 1PU4A 2SQCA 1N23A 5DHIA 3BUDA 1N4QB 4BZEA 1O6RA 1NS8A 3HXCB 2WMFA 2F6DA 1KWFA 3BS6A 1O6QA 4C1SA 4WU0A 2WY7A 3RRSA 1HMWA 4D8OA 2EADA 1TN7B 1MMUA 2BT3A 2Y74A 2WW2A 2WOFA 4QT9A 2C11A 2CWUA 3AMOA 3CV5A 4AYPA 1W2ZA 3DCDA 2H6GB 2RI8A 3RSYA 3A24A 3Q75B 4F13A 3BUPA 2Q1FA 4TF4A 1NSVA 4FNRA 2BRWA 3SFXB 1ULVA 3PYAA 3HI7A 3QWTA 3HIGA 3ACSA 5EATA 1W7CA 3DX4A 3PZ1B 1PX3A 3H3KA 2XN1A 1DOGA 3HXEB 5ILIA 3BVWA 1N9AB 1WZZA 1KKTA 1LOHA 4EHMB 4ZH5A 2HTAA 4K35A 2RGKA 3X42A 1FT2B 4BZHA 4YDEB 1JZ2A 4FUSA 3PGBA 4BTYA 3BLCA 1PS3A 2BB5A 1LURA 1DCEB 3MPHA 3K25A 1HV6A 4Q2BA 1LTXB 4Z4LA 3QT9A 1K72A 5FOBB 1W5ZA 3NJVA 1O1RB 3S4DA 3GT5A 3DSXB 3VSNA 2CISA 3EJSA 3VD7A 3D5SA 5CD2A 3WFAA 2KXSA 5JPNB 1LD7B 1LF9A 3DRAB 1JZ3A 2IEJB 2V8JA 1TXKA 3DX3A 5ILYA 2WMHA 1MN0A 1FPPB 1SO0A 2WY8A 1TQSA 1N7RA 4V1SA 1IVVA 3BLBA 2FBAA 4FJQA 1V5CA 3BVUA 3DYOA 1W6GA 1CB8A 1TN6B 2CQTA 3NFVA 3BGAA 1JZ5A 3M02A 2WCOA 1J0MA 1HN0A 3KN4A 5JPMB 3E1F1 1TF4A 3M01A 5MEHA 3N0GA 2V8KA 3IAQA 3J7HA 2FYVA 2B4FA 1H12A 3M7CA 1QALA 3Q1NA 3T09A 1IA7A 4OJZA 3DSWB 1MMYA 1F9GA 1H39A 1US1A 5KBPA 4FNVA 3EJRA 4FNUA 3DSSB 3BVVA 3OBAA 2WMGA 4ZRPA 2W0QA 1NS4A 1QQFA 3X40A 1X9DA 1HZFA 3X3ZA 3K5TA 1FCEA 4RNLA 2A73B 4KKJA 2WINB 1TQWA 1XWTA 1W6CA 1JOVA 3IMHA 5E1QA 1TNOB 4J5TA 1XW2A 5IKAA 1G9JA 1SIIA 5GY3A 4MU9A 4NEIA 5FO7B 1RWFA 2PMVA 4Q88A 1H35A 1RWGA 4DODA 3PZ4B 1K1WA 5IL8A 1H37A 1N7OA 1JZ8A 1NS2A 1CLCA 1N94B 4DOEA 1HM2A 2DRSA 3CU7A 1RQ5A 2WVXA 1W4NA 1QBQB 3RX5A 4D1JA 3UD2A 2B39A 2CWVA 3VXDA 1LF6A 1HMUA 3KBUC 4JJJA 3M7EA 1O7DD 2D1WA 3H7LA 3HIIA 3EJPA 5GZKA 2CFWA 4M76A 5JMFA 1D6YA 1UI7A 3M71A 2E2VA 2OQEC 1N1ZA 5C05A 1QAFA 3WKFA 1D6UA 2BRVX 1N7QA 3EUVB 2EAEA 2JKAA 1TNZB 4GTTB 2DRQA 4E1YA 5FO8B 4KTRA 2E2UA 1KS8A 3S9VA 4EV5A 2XQWA 3BUBA 1SA4B 4KFDA 2OQEA 1UG9A 5DGRA 2OKXA 3WIQA 3T2PA 2H6IB 3AMOB 1O1TB 1N20A 2PNCA 1KSIA 3DSUB 2CWTA 4FNSA 2E22A 3TY1A 1KZOB 1N4SB 1HXAA 2VN7A 4LNVA 4EL8A 4BTWA 1L1YA 1HTYA 1HXCA 4AYRA 3WC3A 1NSMA 3VD3A 1QAZA 1NSRA 1V5DA 3ECQA 1HXKA 3LVTA 2JG0A 3KSQB 3MUY1 2DRRA 2ZXQA 1D8DB 1UI8A 3EJTA 2CFLA 3C72B 2F0YB 3MV11 3WKHA 3W7UA 4ZH1A 1JCSB 3I3EA 3OS7A 2YX9A 1GXMA 5DGQA 2X03A 1RJOA 1NS0A 2G0DA 4OZWA 1EKMA 2WMKA 4DLQA 3M72A 4GTQB 2OW6A 3W7TA 4GTVB 4D4CA 1DP0A 2RI9A 4CJ0A 3KIIA 1W3YA 1AV4A 3VSMA 1AYXA 1QX1A 2XN0A 2FV0A 3KSLB 5IM1A 3GLYA 2WOHA 5CA3A 1RWAA 1HXGA 2P0VA 2DROA 1IVUA 1NS7A 1FO2A 2CFKA 3E32B 1LXKA 3D52A 5ILJA 3NJXA 3SAEA 3SXXA 2ZBLA 1WMPA 2HTBA 1RWCA 2H6HB 2F7QA 3T08A 2JKEA 2WIIB 4GTOB 3UD1A 3PZ2B 4CE7A 3NREA 3OB8A 3M7LA 4RNQA 1TNYB 1JZ4A 1XWQA 4L6XA 5EAUA 4GTRB 4DI5A 4XUVA 3M75A 1C82A 2XHNA 1VD5A 4DUVA 3EJQA 1TNUB 4D4DA 2ALWA 3QT3A 3D50A 1FP3A 3A3VA 1NKGA 4D4AA 3NBJA 3G4FA 3T2OA 1GHQA 1X1JA 2WVYA 3S4CA 2WW1A 1N7NA 5DHKA 2WVZA 4AYQA 1G9GA 3VW5A 3EU8A 3NNBA 4D72A 4KFEA 4BTXA 4ONTA 4KFFA 2NVPA 4D6IA 4CJ1A 1GAIA 4GL3A 1A2VA 3VDBA 3VDAA 1FBOA 3D4ZA 2WGQA 2YFOA 2OOVC 4LIXA 3DDFA 1TQVA 1GXOA 2J5CA 1KREA 3QPFA 1F4AA 2CFGA 3WA3A 3Q73B 1IVXA 3E37B 3AFLA 1SNZA 3S4AA 1L7KA 2PN5A 1H3AA 2CFDA 1LD8B 3M73A 4GTPB 4F10A 1NSUA 1H3BA 1GA2A 3W7SA 3M78A 2JKPA 1K1YA 3BVXA 3E73A 2XFGA 4D6HA 1FT1B 3D51A 3W7WA 1KSCA 4KTPA 1R76A 1I8QA 2VN4A 3NBBA 2AHFA 1FO3A 4FXKB 1UMPA 1FMIA 3SDRA 2WVXB 3M00A 1HWWA 2F18A 1JZ7A 2V3NA 1O5MB 5CZLA 1D8EB 3QFYA 4D71A 5IK9A 4FNPA 1N4PB 1MZCB 1IS9A 4TXTA 3K11A 3Q78B 3WKIA 1L7JA 2ZQ0A 3BUIA 1IQXA 2F7RA 4D6EA 4FXGB 5M7YA 3I3DA 1PX4A 1AGMA 2WYHA 4YCRA 2V8IA 3WIRA 2WMJA 2QNOA 3E34B 1N1BA 1N7PA 4DUWA 3CZNA 5IL3A 2CQSA 1OJMA 2F1BA 1OJNA 1JS4A 2GH4A 3W5MA 1R33A 4D6DA 2XWJB 1HN1A 3SDTA 3BVTA 2BB6A 4D6CA 1N24A 3SX1A 1JCRB 2ZZRA 3HXFB 5M7IA 1IVWA 4K3AA 5ILZA 2FUTA 3DX2A 3MUZ1 1JYNA 1SPUA 3MWXA 1N4RB 3E33B 5AGDA 1RKYA 3X3YA 4D6FA 1NXCA 3E80A 1OJPA 3PYBA 1Z45A 1OACA 2BBCA 3QXFA 1GSZA 4GTMB 5ILDA 3KQ4A 1N9EA 2ONGA 1SIHA 1O6HA 2XWBB 2WYIA 3DSTB 1JRQA 3H2WA 2E2TA 2EABA 3ON6A 2WMIA 3P2CA 3ACTA 1H54A 2FUQA 2R2LB 1H3CA 3SQCA 1N21A 4FNQA 3SDVA 3QXQA 3ANJA 1TQUA 2AHGA 1S64B 3SDQA 3T0AA 1R34A 1F9OA 1KSDA 1TN8B 3EU5B 1O79A 1WU6A 1QWNA 2WW0A 3HXBB 1D6ZA 3RX7A 4AYOA 3DYMA 2G02A 1N95B 5IK0A 3D5RA 4WVBA 3CZSA 1OJOA 2H6FB 3PMMA 4V1RA 3D3IA 4LNGB 3CZJA 2F7PA 3X3XA 4DUXA 2WZSA 3T0UA 1X1HA 3MV01 2ZIRB 3RX8A 3EJUA 1TU5A 1UT9A 1GXNA 2CG1A 2FUZA 1F4HA 1NI1B 1JYVA 3EZ8A 2OW7A 5E2JA 5ILHA 2ZISB 4GAXA 5KKBA 2BEDB 2A8ZA 5FO9B 1C3DA 1LVNA 1H14A 3PZ3B 3T0BA 4D6JA 4FNTA 2F7OA 3N0FA 1HX9A 1JZ6A 1JYXA 4DLOA 3D4YA 4KKIA 3E7JA 3QDEA 2D73A 2V3PA 2YIKA 1WMOA 2WO0A 3LOYA 2AFAA 3DYPA 4ZG8A 4AQ0A 3VDCA 1KZPB 2KXRA 1V7XA 1MMZA 1NSZA 5IK6A 2JJBA 4WVAA 3CIHA 3U7VA 1QWUA 3X17A 1KFGA 3WIWA 3IAPA 1NL4B 3QG0A 1WU5A 3DECA 4OK4A 5EASA 3RENA 1SA5B 1W6JA 3ANKA 4BOJA 4GTSB 2FV1A 1MMXA 3DPYB 1QAKA 3P5RA 1NC5A 1H13A 2I07B 3HXDB 4D94A 1YGAA 1N22A 3WKGA 3WA2X 3M7BA 3ANIA 3DSVB 2ZL8A 1FAEA 3VD9A 4MBGB 2D8LA 1W6KA 1H36A 2Y73A 4TTGA 3BUQA 3LZ9A 1AVLA 1TQTA 3KLSA 2WW3A 1S63B 3SEPA 2C10A 1WMNA 2Z07A 4OZVA 1HM3A 4L9PB 3MI6A 4UFCA 2GOXA 2JF4A 3S4BA 1K1XA 2OOVA 2E24A 5IKHA 4D4BA 1V7VA 1NSXA 1F1SA 1IA6A 3M74A 3WVFA 4BZGA 2XN2A 3OXUA 3Q7AB 1L2AA 1F9DA 4EV2A 2WYNA 3OEDA 3G6JB 3GZKA 3T0DA 4LNBB 5ILKA 1X1IA 2CIRA 3M76A 3F59A 2WDAA 1X81B 3AFJA 5GW7A 4BZFA 1NSSA 1GAHA 1IQYA 3DDGA 2YFNA 3T2QA 2GZ6A 2F1AA 2CG0A 4MMHA 3VD4A 1J0NA 4Z4JA 3X41A 3W7XA 1O1SB 3M77A 3QR8A 3ALAA 1IU7A 2WMIB 3TF4A 3VD5A 1EGUA 3WUXA 4OK2A 1G87A 1KRFA 4D6GA 1JYWA 1YQ2A 3I3BA 4MMIA 4D1IA 2CIQA 3QFZA 5JMDA 2EACA 3PQIA 4BOKA 1WU4A 1DYUA 1JCQB 1SQCA 4YDOB 1RWHA 3G4DA 1CEMA 3P5PA 2D5JA 1V7WA 1FBWA 3E6UA 3DX1A 2RDYA 5A1AA 3KBTC 1QSJA 3Q79B 3EQAA 1AVKA 3SFYB 2XSGA 1LXMA 2ONHA 3E30B 3RJ3A 2BRPA 4WVCA 3SDUA 1DL2A 4L0GA 3Q7FB 3K7XA 3T33A 3QRYA 4ZRQA 3N9HA 1TNBB 1G6IA 2NOJA 3W5NA 3DX0A
chains in the Genus database with same CATH topology
1X1HA 3MV01 4D72A 1RW9A 1RWGA 3A0OA 1K1WA 4D6IA 1F4HA 1JYVA 1N7OA 1JZ8A 3VDBA 1NS2A 3VDAA 2WZSA 4BZEA 1NS8A 2WMFA 1HM2A 3T0BA 2WVXA 3BS6A 4D6JA 1HMWA 1JZ6A 1JYXA 1F4AA 1MMUA 2WW2A 1LF6A 3E7JA 2D73A 1HMUA 3DCDA 3DYPA 3AFLA 4AQ0A 1SNZA 3VDCA 1MMZA 1NSZA 1L7KA 3A24A 5JMFA 4F13A 4F10A 2Q1FA 1NSUA 1NSVA 3WVFA 2JKPA 3IAPA 2BRWA 1K1YA 2BRVX 1N7QA 1ULVA 3DECA 4OK4A 4D6HA 2JKAA 1PX3A 1I8QA 4E1YA 1MMXA 1LOHA 1JZ2A 2WVXB 2HTAA 4BZHA 1JZ7A 1YGAA 1UG9A 4D71A 3T2PA 3BLCA 3VD9A 2ZQ0A 1L7JA 1LURA 4TTGA 3K25A 2WW3A 1HV6A 2E22A 3TY1A 4D6EA 3I3DA 3SEPA 1PX4A 4OZVA 1HM3A 3NJVA 2WMJA 1K1XA 2E24A 1NSMA 1NSXA 3VSNA 3VD3A 1F1SA 1QAZA 1NSRA 2CISA 3VD7A 4BZGA 3WFAA 1N7PA 3ECQA 4DUWA 1LF9A 1OJMA 3MUY1 1OJNA 1JZ3A 2ZXQA 4D6DA 3T0DA 2CIRA 1X1IA 1HN1A 1TXKA 3MV11 4D6CA 2WMHA 1MN0A 1SO0A 3I3EA 3OS7A 1N7RA 2X03A 2FUTA 2WDAA 1NS0A 3DYOA 3MUZ1 4BZFA 1JYNA 1NSSA 4OZWA 3MWXA 2WMKA 1CB8A 3NFVA 3BGAA 3T2QA 1JZ5A 1DP0A 2WCOA 1W3YA 1J0MA 1J0NA 1HN0A 4MMHA 4D6FA 3VD4A 3E80A 1OJPA 3E1F1 1Z45A 3VSMA 3IAQA 3J7HA 3T09A 3Q1NA 3VD5A 1EGUA 4OJZA 1RWAA 4OK2A 1MMYA 1F9GA 4D6GA 2WMIA 1NS7A 1JYWA 1YQ2A 3I3BA 4FNVA 4MMIA 1LXKA 2CIQA 2FUQA 5JMDA 3NJXA 3OBAA 2HTBA 2WMGA 1RWCA 3T08A 2JKEA 3T0AA 1RWHA 1NS4A 2WW0A 3NREA 3OB8A 1JZ4A 3DYMA 4RNLA 1C82A 5A1AA 2XHNA 4DUVA 3IMHA 1OJOA 1JOVA 1LXMA 2XSGA 4J5TA 5E1QA 2BRPA 1NKGA 3CZJA 3T2OA 4DUXA 1X1JA 2WVYA 2WW1A 1N7NA 4NEIA 2WVZA 1RWFA 2WMIB 3NNBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X1H A;  3MV0 1;  4D72 A;  1RW9 A;  1RWG A;  3A0O A;  1K1W A;  4D6I A;  1F4H A;  1JYV A;  1N7O A;  1JZ8 A;  3VDB A;  1NS2 A;  3VDA A;  2WZS A;  4BZE A;  1NS8 A;  2WMF A;  1HM2 A;  3T0B A;  2WVX A;  4D6J A;  1HMW A;  1JZ6 A;  1JYX A;  1F4A A;  1MMU A;  2WW2 A;  1LF6 A;  3E7J A;  2D73 A;  1HMU A;  3DCD A;  3DYP A;  3AFL A;  4AQ0 A;  1SNZ A;  3VDC A;  1MMZ A;  1NSZ A;  1L7K A;  3A24 A;  5JMF A;  4F13 A;  4F10 A;  2Q1F A;  1NSU A;  1NSV A;  2JKP A;  3IAP A;  2BRW A;  1K1Y A;  2BRV X;  1N7Q A;  1ULV A;  3DEC A;  4OK4 A;  4D6H A;  2JKA A;  1PX3 A;  1I8Q A;  4E1Y A;  1MMX A;  1LOH A;  1JZ2 A;  2WVX B;  2HTA A;  4BZH A;  1JZ7 A;  1YGA A;  1UG9 A;  4D71 A;  3T2P A;  3VD9 A;  2ZQ0 A;  1L7J A;  1LUR A;  4TTG A;  3K25 A;  2WW3 A;  1HV6 A;  2E22 A;  4D6E A;  3I3D A;  3SEP A;  1PX4 A;  4OZV A;  1HM3 A;  3NJV A;  2WMJ A;  1K1X A;  2E24 A;  1NSM A;  1NSX A;  3VSN A;  3VD3 A;  1F1S A;  1QAZ A;  1NSR A;  2CIS A;  3VD7 A;  4BZG A;  3WFA A;  1N7P A;  3ECQ A;  4DUW A;  1LF9 A;  1OJM A;  3MUY 1;  1OJN A;  1JZ3 A;  2ZXQ A;  4D6D A;  3T0D A;  2CIR A;  1X1I A;  1HN1 A;  1TXK A;  3MV1 1;  4D6C A;  2WMH A;  1MN0 A;  1SO0 A;  3I3E A;  3OS7 A;  1N7R A;  2X03 A;  2FUT A;  2WDA A;  1NS0 A;  3DYO A;  3MUZ 1;  4BZF A;  1JYN A;  1NSS A;  4OZW A;  3MWX A;  2WMK A;  1CB8 A;  3NFV A;  3BGA A;  3T2Q A;  1JZ5 A;  1DP0 A;  2WCO A;  1W3Y A;  1J0M A;  1J0N A;  1HN0 A;  4MMH A;  4D6F A;  3VD4 A;  3E80 A;  1OJP A;  3E1F 1;  1Z45 A;  3VSM A;  3IAQ A;  3J7H A;  3T09 A;  3Q1N A;  3VD5 A;  1EGU A;  4OJZ A;  1RWA A;  4OK2 A;  1MMY A;  1F9G A;  4D6G A;  2WMI A;  1NS7 A;  1JYW A;  1YQ2 A;  3I3B A;  4FNV A;  4MMI A;  1LXK A;  2CIQ A;  2FUQ A;  5JMD A;  3NJX A;  3OBA A;  2HTB A;  2WMG A;  1RWC A;  3T08 A;  2JKE A;  3T0A A;  1RWH A;  1NS4 A;  2WW0 A;  3NRE A;  3OB8 A;  1JZ4 A;  3DYM A;  4RNL A;  1C82 A;  5A1A A;  2XHN A;  4DUV A;  3IMH A;  1OJO A;  1JOV A;  1LXM A;  2XSG A;  5E1Q A;  2BRP A;  1NKG A;  3CZJ A;  3T2O A;  4DUX A;  1X1J A;  2WVY A;  2WW1 A;  1N7N A;  4NEI A;  2WVZ A;  1RWF A;  2WMI B;  3NNB A; 
#chains in the Genus database with same CATH topology
 1GLM A;  1RW9 A;  3A0O A;  1HCU A;  3QSP A;  1PU4 A;  2SQC A;  1N23 A;  5DHI A;  3BUD A;  1N4Q B;  4BZE A;  1O6R A;  1NS8 A;  3HXC B;  2WMF A;  2F6D A;  1KWF A;  3BS6 A;  1O6Q A;  4C1S A;  4WU0 A;  2WY7 A;  3RRS A;  1HMW A;  4D8O A;  2EAD A;  1TN7 B;  1MMU A;  2BT3 A;  2Y74 A;  2WW2 A;  2WOF A;  4QT9 A;  2C11 A;  2CWU A;  3AMO A;  3CV5 A;  4AYP A;  1W2Z A;  3DCD A;  2H6G B;  2RI8 A;  3RSY A;  3A24 A;  3Q75 B;  4F13 A;  3BUP A;  2Q1F A;  4TF4 A;  1NSV A;  4FNR A;  2BRW A;  3SFX B;  1ULV A;  3PYA A;  3HI7 A;  3QWT A;  3HIG A;  3ACS A;  5EAT A;  1W7C A;  3DX4 A;  3PZ1 B;  1PX3 A;  3H3K A;  2XN1 A;  1DOG A;  3HXE B;  5ILI A;  3BVW A;  1N9A B;  1WZZ A;  1KKT A;  1LOH A;  4EHM B;  4ZH5 A;  2HTA A;  4K35 A;  2RGK A;  3X42 A;  1FT2 B;  4BZH A;  4YDE B;  1JZ2 A;  4FUS A;  3PGB A;  4BTY A;  3BLC A;  1PS3 A;  2BB5 A;  1LUR A;  1DCE B;  3MPH A;  3K25 A;  1HV6 A;  4Q2B A;  1LTX B;  4Z4L A;  3QT9 A;  1K72 A;  5FOB B;  1W5Z A;  3NJV A;  1O1R B;  3S4D A;  3GT5 A;  3DSX B;  3VSN A;  2CIS A;  3EJS A;  3VD7 A;  3D5S A;  5CD2 A;  3WFA A;  2KXS A;  5JPN B;  1LD7 B;  1LF9 A;  3DRA B;  1JZ3 A;  2IEJ B;  2V8J A;  1TXK A;  3DX3 A;  5ILY A;  2WMH A;  1MN0 A;  1FPP B;  1SO0 A;  2WY8 A;  1TQS A;  1N7R A;  4V1S A;  1IVV A;  3BLB A;  2FBA A;  4FJQ A;  1V5C A;  3BVU A;  3DYO A;  1W6G A;  1CB8 A;  1TN6 B;  2CQT A;  3NFV A;  3BGA A;  1JZ5 A;  3M02 A;  2WCO A;  1J0M A;  1HN0 A;  3KN4 A;  5JPM B;  3E1F 1;  1TF4 A;  3M01 A;  5MEH A;  3N0G A;  2V8K A;  3IAQ A;  3J7H A;  2FYV A;  2B4F A;  1H12 A;  3M7C A;  1QAL A;  3Q1N A;  3T09 A;  1IA7 A;  4OJZ A;  3DSW B;  1MMY A;  1F9G A;  1H39 A;  1US1 A;  5KBP A;  4FNV A;  3EJR A;  4FNU A;  3DSS B;  3BVV A;  3OBA A;  2WMG A;  4ZRP A;  2W0Q A;  1NS4 A;  1QQF A;  3X40 A;  1X9D A;  1HZF A;  3X3Z A;  3K5T A;  1FCE A;  4RNL A;  2A73 B;  4KKJ A;  2WIN B;  1TQW A;  1XWT A;  1W6C A;  1JOV A;  3IMH A;  5E1Q A;  1TNO B;  4J5T A;  1XW2 A;  5IKA A;  1G9J A;  1SII A;  5GY3 A;  4MU9 A;  4NEI A;  5FO7 B;  1RWF A;  2PMV A;  4Q88 A;  1H35 A;  1RWG A;  4DOD A;  3PZ4 B;  1K1W A;  5IL8 A;  1H37 A;  1N7O A;  1JZ8 A;  1NS2 A;  1CLC A;  1N94 B;  4DOE A;  1HM2 A;  2DRS A;  3CU7 A;  1RQ5 A;  2WVX A;  1W4N A;  1QBQ B;  3RX5 A;  4D1J A;  3UD2 A;  2B39 A;  2CWV A;  3VXD A;  1LF6 A;  1HMU A;  3KBU C;  4JJJ A;  3M7E A;  1O7D D;  2D1W A;  3H7L A;  3HII A;  3EJP A;  5GZK A;  2CFW A;  4M76 A;  5JMF A;  1D6Y A;  1UI7 A;  3M71 A;  2E2V A;  2OQE C;  1N1Z A;  5C05 A;  1QAF A;  3WKF A;  1D6U A;  2BRV X;  1N7Q A;  3EUV B;  2EAE A;  2JKA A;  1TNZ B;  4GTT B;  2DRQ A;  4E1Y A;  5FO8 B;  4KTR A;  2E2U A;  1KS8 A;  3S9V A;  4EV5 A;  2XQW A;  3BUB A;  1SA4 B;  4KFD A;  2OQE A;  1UG9 A;  5DGR A;  2OKX A;  3WIQ A;  3T2P A;  2H6I B;  3AMO B;  1O1T B;  1N20 A;  2PNC A;  1KSI A;  3DSU B;  2CWT A;  4FNS A;  2E22 A;  3TY1 A;  1KZO B;  1N4S B;  1HXA A;  2VN7 A;  4LNV A;  4EL8 A;  4BTW A;  1L1Y A;  1HTY A;  1HXC A;  4AYR A;  3WC3 A;  1NSM A;  3VD3 A;  1QAZ A;  1NSR A;  1V5D A;  3ECQ A;  1HXK A;  3LVT A;  2JG0 A;  3KSQ B;  3MUY 1;  2DRR A;  2ZXQ A;  1D8D B;  1UI8 A;  3EJT A;  2CFL A;  3C72 B;  2F0Y B;  3MV1 1;  3WKH A;  3W7U A;  4ZH1 A;  1JCS B;  3I3E A;  3OS7 A;  2YX9 A;  1GXM A;  5DGQ A;  2X03 A;  1RJO A;  1NS0 A;  2G0D A;  4OZW A;  1EKM A;  2WMK A;  4DLQ A;  3M72 A;  4GTQ B;  2OW6 A;  3W7T A;  4GTV B;  4D4C A;  1DP0 A;  2RI9 A;  4CJ0 A;  3KII A;  1W3Y A;  1AV4 A;  3VSM A;  1AYX A;  1QX1 A;  2XN0 A;  2FV0 A;  3KSL B;  5IM1 A;  3GLY A;  2WOH A;  5CA3 A;  1RWA A;  1HXG A;  2P0V A;  2DRO A;  1IVU A;  1NS7 A;  1FO2 A;  2CFK A;  3E32 B;  1LXK A;  3D52 A;  5ILJ A;  3NJX A;  3SAE A;  3SXX A;  2ZBL A;  1WMP A;  2HTB A;  1RWC A;  2H6H B;  2F7Q A;  3T08 A;  2JKE A;  2WII B;  4GTO B;  3UD1 A;  3PZ2 B;  4CE7 A;  3NRE A;  3OB8 A;  3M7L A;  4RNQ A;  1TNY B;  1JZ4 A;  1XWQ A;  4L6X A;  5EAU A;  4GTR B;  4DI5 A;  4XUV A;  3M75 A;  1C82 A;  2XHN A;  1VD5 A;  4DUV A;  3EJQ A;  1TNU B;  4D4D A;  2ALW A;  3QT3 A;  3D50 A;  1FP3 A;  3A3V A;  1NKG A;  4D4A A;  3NBJ A;  3G4F A;  3T2O A;  1GHQ A;  1X1J A;  2WVY A;  3S4C A;  2WW1 A;  1N7N A;  5DHK A;  2WVZ A;  4AYQ A;  1G9G A;  3VW5 A;  3EU8 A;  3NNB A;  4D72 A;  4KFE A;  4BTX A;  4ONT A;  4KFF A;  2NVP A;  4D6I A;  4CJ1 A;  1GAI A;  4GL3 A;  1A2V A;  3VDB A;  3VDA A;  1FBO A;  3D4Z A;  2WGQ A;  2YFO A;  2OOV C;  4LIX A;  3DDF A;  1TQV A;  1GXO A;  2J5C A;  1KRE A;  3QPF A;  1F4A A;  2CFG A;  3WA3 A;  3Q73 B;  1IVX A;  3E37 B;  3AFL A;  1SNZ A;  3S4A A;  1L7K A;  2PN5 A;  1H3A A;  2CFD A;  1LD8 B;  3M73 A;  4GTP B;  4F10 A;  1NSU A;  1H3B A;  1GA2 A;  3W7S A;  3M78 A;  2JKP A;  1K1Y A;  3BVX A;  3E73 A;  2XFG A;  4D6H A;  1FT1 B;  3D51 A;  3W7W A;  1KSC A;  4KTP A;  1R76 A;  1I8Q A;  2VN4 A;  3NBB A;  2AHF A;  1FO3 A;  4FXK B;  1UMP A;  1FMI A;  3SDR A;  2WVX B;  3M00 A;  1HWW A;  2F18 A;  1JZ7 A;  2V3N A;  1O5M B;  5CZL A;  1D8E B;  3QFY A;  4D71 A;  5IK9 A;  4FNP A;  1N4P B;  1MZC B;  1IS9 A;  4TXT A;  3K11 A;  3Q78 B;  3WKI A;  1L7J A;  2ZQ0 A;  3BUI A;  1IQX A;  2F7R A;  4D6E A;  4FXG B;  5M7Y A;  3I3D A;  1PX4 A;  1AGM A;  2WYH A;  4YCR A;  2V8I A;  3WIR A;  2WMJ A;  2QNO A;  3E34 B;  1N1B A;  1N7P A;  4DUW A;  3CZN A;  5IL3 A;  2CQS A;  1OJM A;  2F1B A;  1OJN A;  1JS4 A;  2GH4 A;  3W5M A;  1R33 A;  4D6D A;  2XWJ B;  1HN1 A;  3SDT A;  3BVT A;  2BB6 A;  4D6C A;  1N24 A;  3SX1 A;  1JCR B;  2ZZR A;  3HXF B;  5M7I A;  1IVW A;  4K3A A;  5ILZ A;  2FUT A;  3DX2 A;  3MUZ 1;  1JYN A;  1SPU A;  3MWX A;  1N4R B;  3E33 B;  5AGD A;  1RKY A;  3X3Y A;  4D6F A;  1NXC A;  3E80 A;  1OJP A;  3PYB A;  1Z45 A;  1OAC A;  2BBC A;  3QXF A;  1GSZ A;  4GTM B;  5ILD A;  3KQ4 A;  1N9E A;  2ONG A;  1SIH A;  1O6H A;  2XWB B;  2WYI A;  3DST B;  1JRQ A;  3H2W A;  2E2T A;  2EAB A;  3ON6 A;  2WMI A;  3P2C A;  3ACT A;  1H54 A;  2FUQ A;  2R2L B;  1H3C A;  3SQC A;  1N21 A;  4FNQ A;  3SDV A;  3QXQ A;  3ANJ A;  1TQU A;  2AHG A;  1S64 B;  3SDQ A;  3T0A A;  1R34 A;  1F9O A;  1KSD A;  1TN8 B;  3EU5 B;  1O79 A;  1WU6 A;  1QWN A;  2WW0 A;  3HXB B;  1D6Z A;  3RX7 A;  4AYO A;  3DYM A;  2G02 A;  1N95 B;  5IK0 A;  3D5R A;  4WVB A;  3CZS A;  1OJO A;  2H6F B;  3PMM A;  4V1R A;  3D3I A;  4LNG B;  3CZJ A;  2F7P A;  3X3X A;  4DUX A;  2WZS A;  3T0U A;  1X1H A;  3MV0 1;  2ZIR B;  3RX8 A;  3EJU A;  1TU5 A;  1UT9 A;  1GXN A;  2CG1 A;  2FUZ A;  1F4H A;  1NI1 B;  1JYV A;  3EZ8 A;  2OW7 A;  5E2J A;  5ILH A;  2ZIS B;  4GAX A;  5KKB A;  2BED B;  2A8Z A;  5FO9 B;  1C3D A;  1LVN A;  1H14 A;  3PZ3 B;  3T0B A;  4D6J A;  4FNT A;  2F7O A;  3N0F A;  1HX9 A;  1JZ6 A;  1JYX A;  4DLO A;  3D4Y A;  4KKI A;  3E7J A;  3QDE A;  2D73 A;  2V3P A;  2YIK A;  1WMO A;  2WO0 A;  3LOY A;  2AFA A;  3DYP A;  4ZG8 A;  4AQ0 A;  3VDC A;  1KZP B;  2KXR A;  1V7X A;  1MMZ A;  1NSZ A;  5IK6 A;  2JJB A;  4WVA A;  3CIH A;  3U7V A;  1QWU A;  3X17 A;  1KFG A;  3WIW A;  3IAP A;  1NL4 B;  3QG0 A;  1WU5 A;  3DEC A;  4OK4 A;  5EAS A;  3REN A;  1SA5 B;  1W6J A;  3ANK A;  4BOJ A;  4GTS B;  2FV1 A;  1MMX A;  3DPY B;  1QAK A;  3P5R A;  1NC5 A;  1H13 A;  2I07 B;  3HXD B;  4D94 A;  1YGA A;  1N22 A;  3WKG A;  3WA2 X;  3M7B A;  3ANI A;  3DSV B;  2ZL8 A;  1FAE A;  3VD9 A;  4MBG B;  2D8L A;  1W6K A;  1H36 A;  2Y73 A;  4TTG A;  3BUQ A;  3LZ9 A;  1AVL A;  1TQT A;  3KLS A;  2WW3 A;  1S63 B;  3SEP A;  2C10 A;  1WMN A;  2Z07 A;  4OZV A;  1HM3 A;  4L9P B;  3MI6 A;  4UFC A;  2GOX A;  2JF4 A;  3S4B A;  1K1X A;  2OOV A;  2E24 A;  5IKH A;  4D4B A;  1V7V A;  1NSX A;  1F1S A;  1IA6 A;  3M74 A;  3WVF A;  4BZG A;  2XN2 A;  3OXU A;  3Q7A B;  1L2A A;  1F9D A;  4EV2 A;  2WYN A;  3OED A;  3G6J B;  3GZK A;  3T0D A;  4LNB B;  5ILK A;  1X1I A;  2CIR A;  3M76 A;  3F59 A;  2WDA A;  1X81 B;  3AFJ A;  5GW7 A;  4BZF A;  1NSS A;  1GAH A;  1IQY A;  3DDG A;  2YFN A;  3T2Q A;  2GZ6 A;  2F1A A;  2CG0 A;  4MMH A;  3VD4 A;  1J0N A;  4Z4J A;  3X41 A;  3W7X A;  1O1S B;  3M77 A;  3QR8 A;  3ALA A;  1IU7 A;  2WMI B;  3TF4 A;  3VD5 A;  1EGU A;  3WUX A;  4OK2 A;  1G87 A;  1KRF A;  4D6G A;  1JYW A;  1YQ2 A;  3I3B A;  4MMI A;  4D1I A;  2CIQ A;  3QFZ A;  5JMD A;  2EAC A;  3PQI A;  4BOK A;  1WU4 A;  1DYU A;  1JCQ B;  1SQC A;  4YDO B;  1RWH A;  3G4D A;  1CEM A;  3P5P A;  2D5J A;  1V7W A;  1FBW A;  3E6U A;  3DX1 A;  2RDY A;  5A1A A;  3KBT C;  1QSJ A;  3Q79 B;  3EQA A;  1AVK A;  3SFY B;  2XSG A;  1LXM A;  2ONH A;  3E30 B;  3RJ3 A;  2BRP A;  4WVC A;  3SDU A;  1DL2 A;  4L0G A;  3Q7F B;  3K7X A;  3T33 A;  3QRY A;  4ZRQ A;  3N9H A;  1TNB B;  1G6I A;  2NOJ A;  3W5N A;  3DX0 A; 
#chains in the Genus database with same CATH homology
 1X1H A;  3MV0 1;  4D72 A;  1RW9 A;  1RWG A;  3A0O A;  1K1W A;  4D6I A;  1F4H A;  1JYV A;  1N7O A;  1JZ8 A;  3VDB A;  1NS2 A;  3VDA A;  2WZS A;  4BZE A;  1NS8 A;  2WMF A;  1HM2 A;  3T0B A;  2WVX A;  3BS6 A;  4D6J A;  1HMW A;  1JZ6 A;  1JYX A;  1F4A A;  1MMU A;  2WW2 A;  1LF6 A;  3E7J A;  2D73 A;  1HMU A;  3DCD A;  3DYP A;  3AFL A;  4AQ0 A;  1SNZ A;  3VDC A;  1MMZ A;  1NSZ A;  1L7K A;  3A24 A;  5JMF A;  4F13 A;  4F10 A;  2Q1F A;  1NSU A;  1NSV A;  3WVF A;  2JKP A;  3IAP A;  2BRW A;  1K1Y A;  2BRV X;  1N7Q A;  1ULV A;  3DEC A;  4OK4 A;  4D6H A;  2JKA A;  1PX3 A;  1I8Q A;  4E1Y A;  1MMX A;  1LOH A;  1JZ2 A;  2WVX B;  2HTA A;  4BZH A;  1JZ7 A;  1YGA A;  1UG9 A;  4D71 A;  3T2P A;  3BLC A;  3VD9 A;  2ZQ0 A;  1L7J A;  1LUR A;  4TTG A;  3K25 A;  2WW3 A;  1HV6 A;  2E22 A;  3TY1 A;  4D6E A;  3I3D A;  3SEP A;  1PX4 A;  4OZV A;  1HM3 A;  3NJV A;  2WMJ A;  1K1X A;  2E24 A;  1NSM A;  1NSX A;  3VSN A;  3VD3 A;  1F1S A;  1QAZ A;  1NSR A;  2CIS A;  3VD7 A;  4BZG A;  3WFA A;  1N7P A;  3ECQ A;  4DUW A;  1LF9 A;  1OJM A;  3MUY 1;  1OJN A;  1JZ3 A;  2ZXQ A;  4D6D A;  3T0D A;  2CIR A;  1X1I A;  1HN1 A;  1TXK A;  3MV1 1;  4D6C A;  2WMH A;  1MN0 A;  1SO0 A;  3I3E A;  3OS7 A;  1N7R A;  2X03 A;  2FUT A;  2WDA A;  1NS0 A;  3DYO A;  3MUZ 1;  4BZF A;  1JYN A;  1NSS A;  4OZW A;  3MWX A;  2WMK A;  1CB8 A;  3NFV A;  3BGA A;  3T2Q A;  1JZ5 A;  1DP0 A;  2WCO A;  1W3Y A;  1J0M A;  1J0N A;  1HN0 A;  4MMH A;  4D6F A;  3VD4 A;  3E80 A;  1OJP A;  3E1F 1;  1Z45 A;  3VSM A;  3IAQ A;  3J7H A;  3T09 A;  3Q1N A;  3VD5 A;  1EGU A;  4OJZ A;  1RWA A;  4OK2 A;  1MMY A;  1F9G A;  4D6G A;  2WMI A;  1NS7 A;  1JYW A;  1YQ2 A;  3I3B A;  4FNV A;  4MMI A;  1LXK A;  2CIQ A;  2FUQ A;  5JMD A;  3NJX A;  3OBA A;  2HTB A;  2WMG A;  1RWC A;  3T08 A;  2JKE A;  3T0A A;  1RWH A;  1NS4 A;  2WW0 A;  3NRE A;  3OB8 A;  1JZ4 A;  3DYM A;  4RNL A;  1C82 A;  5A1A A;  2XHN A;  4DUV A;  3IMH A;  1OJO A;  1JOV A;  1LXM A;  2XSG A;  4J5T A;  5E1Q A;  2BRP A;  1NKG A;  3CZJ A;  3T2O A;  4DUX A;  1X1J A;  2WVY A;  2WW1 A;  1N7N A;  4NEI A;  2WVZ A;  1RWF A;  2WMI B;  3NNB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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