2EXGA

Making protein-protein interactions drugable: discovery of low-molecular-weight ligands for the af6 pdz domain
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
101
structure length
101
Chain Sequence
GPLGSLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Afadin
total genus 23
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2005-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 2exgA00
2KOMA 1RGWA 2QKTA 2QKVA 3LNXA 1K32A 1X45A 1IU2A 2KPKA 2DAZA 3QJNA 2WL7A 3RLEA 1ZUBA 3I1EA 2W4FA 3RL8A 1UEWA 2YT8A 3DJ3A 2G5MB 1N7FA 2Z17A 4K76A 3CBYA 4OAJA 1QAVA 2I1NA 5GLJA 1WHDA 2L4SA 2KJPA 2VSPA 1SOZA 5EYZA 1X5QA 4JL7A 4F8KA 5HFFA 2KL1A 2M3MA 3KZDA 4Z8JA 2GZVA 3ZRTA 1V6BA 4NNLA 4IC6A 2JWEA 2M0TA 4GVCA 4GHNA 4JOKA 2ZPMA 2M10A 2EAQA 4FGMA 5E6PB 5D13A 4K75A 1WFVA 1GQ4A 1GM1A 1WFGA 5F67A 3K50A 2LUIA 4NMPA 2OSGA 2DC2A 1BE9A 2EDZA 2OZFA 4H11A 4Z33A 4N6XA 5GNDA 5E1YA 1TP5A 3MH6A 1T2MA 4E35A 2M0ZA 1WHAA 4NMSA 1M5ZA 4JOHA 5HFBA 4O06A 2KJDA 4JOEA 4NXRA 1UF1A 3R0HA 2MHOA 3GDUA 5HDYA 2D90A 3QO6A 2ENOA 1W9OA 4NMRA 1WF8A 3ID3A 3L4FD 3SOEA 3VQFA 3GCOA 2KAWA 3ID4A 3VQGA 3PS4A 1FC9A 2K1ZA 3CC0A 2VPHA 1OZIA 2VRFA 4L8NA 3QE1A 2DJTA 5I7ZA 1U37A 4Q2PA 2D92A 2VSVA 4MPAA 1I16A 2DLUA 2H2BA 3HVQC 1UJDA 2V90A 1FC6A 1U3BA 3TSWA 1YBOA 2R4HA 2PA1A 2EEGA 1WI2A 1MFGA 4YYXA 3GJ9A 5HEBA 2KV8A 4Q2OA 5HFEA 1RZXA 1XZ9A 4JOPA 4NNMA 2OMJA 4NMTA 2EGKA 2YUYA 1V62A 5HF1A 3KHFA 1Z86A 3I18A 3TSZA 4Q2NA 2M0VA 2H3MA 2JREA 1WI4A 2EDVA 2PNTA 1QAVB 2YT7A 1Q3PA 3GDVA 3EGGC 2EXGA 2OPGA 2RCZA 3ID2A 3KZEA 2O2TA 4WYTA 1Q7XA 2LA8A 3EGHC 2F5YA 2DB5A 4RI0A 2DMZA 2KPLA 2QT5A 2I4SA 1R6JA 2R3YA 3MH7A 4P0CA 3RL7A 2EEJA 4NMQA 5B6LA 2JILA 4UU6A 2AWXA 3GDSA 3DJ1A 2VZ5A 2KBSA 3HPKA 3E17A 4UU5A 3PV5A 1TQ3A 2LC6A 3R68A 1MFLA 1OBZA 1W9QA 3QIKA 3JXTA 1FCFA 3AXAA 4Q6HA 3O46A 2Q3GA 1Z87A 2I04A 4E34A 2LC7A 2V1WA 2FNEA 2KG2A 2FCFA 3O5NA 3MH4A 2KJKA 2MX6A 4E3BA 4R2ZA 3NGHA 5HFCA 1FC7A 3CS0A 1UJVA 2PZDA 2KOJA 2EDPA 2IWOA 1X5RA 1Y7NA 2KQFA 2E7KA 1N6EA 2KOHA 1KWAA 5E22A 1L6OA 1MC7A 2KA9A 3PV2A 1WG6A 2RRMA 2DKRA 5G1EA 2JXOA 1G9OA 1IHJA 2F0AA 1N99A 4K6YA 5FB8C 1WIFA 3ID1A 1X6DA 2JOAA 1V5LA 2P3WA 2FN5A 3TSVA 2Z9IA 2REYA 1V1TA 4JOFA 5G1DA 1UHPA 1VJ6A 4KFWA 1KY9A 2OQSA 1Y8TA 1V5QA 3CBXA 1P1EA 2I0IA 2Q9VA 2HE4A 2IWQA 2ZPLA 3GGEA 1UM1A 4HOPA 5HF4A 1KEFA 1N6FA 2JIKA 2LOBA 3DIWA 1WJLA 4WYUA 3GCNA 3R69A 3I4WA 2AWUA 1U39A 5H3JA 3FY5A 1N7TA 1ZOKA 1N7EA 1OBXA 2H2CA 2UZCA 2IWPA 2EV8A 3QJMA 4NMOA 5EZ0A 4NXQA 2I6VA 5HEDA 2KYLA 2JINA 1VB7A 4AMHA 2VWRA 3OTPA 2EEHA 2HGAA 2YTWA 1QAUA 3BPUA 2IWNA 2DM8A 2PDZA 4Q6SA 2QBWA 2CSSA 1NTEA 1TP3A 4Q3HA 1B8QA 4REYA 1RY4A 2EGNA 4JOJA 1UEQA 1Q3OA 1VCWA 2CSJA 5A2PA 1PDRA 2G2LA 2YUBA 2HE2A 1VAEA 4K78A 4Q2QA 1WF7A 2BYGA 5HFDA 1NF3C 2OS6A 5HJ1A 3SFJA 5E11A 2H3LA 4GVDA 3DORA 2CS5A 3NFKA 4XHVA 3TMHA 3OU0A 2QG1A 2PKUA 1WH1A 1BFEA 3CYYA 3PV4A 1I92A 3NFLA 2QKUA 3QGLA 3WKLA 1U38A 5JXBA 5HEYA 3LNYA 1VA8A 3K1RA 4PQWA 2KRGA 1UEZA 2EGOA 1LCYA 3SHUA 3DJAA 1UFXA 4OEOA 1X5NA 4YDPA 2AWWA 5HETA 3K82A 5FHTA 3STJA 1UEPA 2DLSA 3HPMA 4HOPB 3B76A 1SOTA 1UJUA 5F3XA 3WKMA 1GQ5A 1W9EA 2EJYA 4OEPA 3PDZA 3CH8A 2K20A 3PDVA 2M0UA 3CBZA 2AINA 1X8SA 3GSLA 1D5GA 4P2AB 5DTHA 5E21A 4JORA 1OBYA 1P1DA 1RGRA 2I0LA 4G69A 1IU0A 2OGPA 1QLCA 2D8IA 4NXPA 2EEIA 2L4TA 4NMVA 3QDOA 1TE0A 2PKTA 2OCSA 2FE5A 2L97A 2EHRA 4JOGA 2X7ZA 2W7RA 1N6DA 1UITA 4LMMA 4KFVA 3SUZA 1UM7A 4K72A 4EDJA 3SHWA
chains in the Genus database with same CATH superfamily
2KOMA 1RGWA 2QKTA 2QKVA 3LNXA 1K32A 1X45A 1IU2A 2KPKA 2DAZA 3QJNA 2WL7A 3RLEA 5ILBA 1ZUBA 3I1EA 2GEFA 2W4FA 3RL8A 1UEWA 2YT8A 3DJ3A 2G5MB 1N7FA 2Z17A 4K76A 3CBYA 4OAJA 1QAVA 2I1NA 5GLJA 1WHDA 2L4SA 2KJPA 2VSPA 1SOZA 5EYZA 1X5QA 4JL7A 4F8KA 5HFFA 2KL1A 2M3MA 3KZDA 4Z8JA 2GZVA 3ZRTA 1V6BA 4NNLA 4IC6A 2JWEA 2M0TA 4GVCA 4GHNA 4JOKA 2ZPMA 2M10A 2EAQA 4FGMA 5E6PB 5D13A 4K75A 1X9ZA 1WFVA 1GQ4A 1GM1A 1WFGA 5F67A 3K50A 2LUIA 4NMPA 2OSGA 2DC2A 1BE9A 2EDZA 2OZFA 4H11A 4Z33A 4N6XA 5GNDA 5E1YA 1TP5A 3MH6A 1T2MA 4E35A 2M0ZA 1WHAA 4NMSA 1M5ZA 4JOHA 5HFBA 4O06A 2KJDA 4JOEA 5IL9A 4NXRA 1UF1A 3R0HA 2MHOA 3GDUA 5HDYA 2D90A 3QO6A 2ENOA 1W9OA 4NMRA 1WF8A 3ID3A 3L4FD 3SOEA 3VQFA 3GCOA 2KAWA 3ID4A 3VQGA 3PS4A 1FC9A 2K1ZA 3CC0A 2VPHA 1OZIA 2VRFA 4JJ3A 4L8NA 3QE1A 4EDJA 2DJTA 5I7ZA 1U37A 4Q2PA 2D92A 2VSVA 4MPAA 1I16A 2DLUA 2H2BA 3HVQC 1UJDA 2V90A 1FC6A 1U3BA 3TSWA 1YBOA 2R4HA 2PA1A 2EEGA 1WI2A 1MFGA 4YYXA 3GJ9A 5HEBA 2KV8A 4Q2OA 5HFEA 1RZXA 1XZ9A 4JOPA 4NNMA 2OMJA 4NMTA 2EGKA 2YUYA 1V62A 5HF1A 4JJ0A 3KHFA 1Z86A 3I18A 3NCVA 3TSZA 4Q2NA 2M0VA 2H3MA 2JREA 1WI4A 2EDVA 2PNTA 1QAVB 2YT7A 1Q3PA 3GDVA 3EGGC 2EXGA 2OPGA 2RCZA 3ID2A 3KZEA 2O2TA 4WYTA 1Q7XA 2LA8A 3EGHC 2F5YA 4FLNA 2DB5A 4RI0A 2DMZA 2KPLA 2QT5A 2I4SA 1R6JA 2R3YA 3MH7A 4P0CA 3RL7A 2EEJA 4NMQA 5B6LA 2JILA 4UU6A 2AWXA 3GDSA 3DJ1A 2VZ5A 2KBSA 3HPKA 3E17A 4UU5A 3PV5A 1TQ3A 2LC6A 3R68A 1MFLA 1OBZA 1W9QA 3QIKA 3JXTA 1FCFA 3AXAA 4Q6HA 3O46A 2Q3GA 1Z87A 2I04A 4E34A 2LC7A 2V1WA 2FNEA 2KG2A 5B42A 2FCFA 3O5NA 3MH4A 2KJKA 2MX6A 4E3BA 4R2ZA 3NGHA 5HFCA 1FC7A 3CS0A 1UJVA 2PZDA 2KOJA 2EDPA 2IWOA 1X5RA 1Y7NA 2KQFA 2E7KA 1N6EA 2KOHA 1KWAA 5E22A 1L6OA 1MC7A 2KA9A 3PV2A 1WG6A 2RRMA 2DKRA 5G1EA 2JXOA 1G9OA 1IHJA 2F0AA 1N99A 4K6YA 5FB8C 1WIFA 3ID1A 1X6DA 2JOAA 1V5LA 2P3WA 2FN5A 3TSVA 2Z9IA 2REYA 1V1TA 4JOFA 5G1DA 3KDKA 1UHPA 1VJ6A 4KFWA 1KY9A 2OQSA 1Y8TA 1V5QA 3CBXA 1P1EA 2I0IA 2Q9VA 2HE4A 2IWQA 2ZPLA 3GGEA 1UM1A 4HOPA 5HF4A 1KEFA 1N6FA 2JIKA 2LOBA 3DIWA 3GABA 1WJLA 4WYUA 3GCNA 3R69A 3I4WA 2AWUA 1U39A 5H3JA 3FY5A 1N7TA 1ZOKA 1N7EA 1OBXA 2H2CA 2UZCA 2IWPA 2EV8A 3QJMA 4NMOA 5EZ0A 4NXQA 2I6VA 5HEDA 2KYLA 2JINA 1VB7A 4AMHA 2VWRA 3OTPA 2EEHA 2HGAA 2YTWA 1QAUA 3BPUA 2IWNA 2DM8A 2PDZA 4Q6SA 2QBWA 2CSSA 1NTEA 1TP3A 4Q3HA 1B8QA 4REYA 1RY4A 2EGNA 4JOJA 1UEQA 1Q3OA 1VCWA 2CSJA 5A2PA 1PDRA 2G2LA 2YUBA 2HE2A 1VAEA 4K78A 4Q2QA 1WF7A 2BYGA 5HFDA 1NF3C 2OS6A 5HJ1A 3SFJA 5E11A 2H3LA 4GVDA 3DORA 2CS5A 3KDGA 3NFKA 4XHVA 3TMHA 3OU0A 2QG1A 2PKUA 1WH1A 1BFEA 3CYYA 3PV4A 1I92A 3NFLA 2QKUA 3QGLA 3WKLA 1U38A 5JXBA 5HEYA 3LNYA 1VA8A 3K1RA 4PQWA 2KRGA 1UEZA 2EGOA 1LCYA 3SHUA 3DJAA 1UFXA 4OEOA 1X5NA 4YDPA 2AWWA 5HETA 3K82A 5FHTA 3STJA 1UEPA 2DLSA 3HPMA 4HOPB 3B76A 1SOTA 1UJUA 5F3XA 3WKMA 1GQ5A 1W9EA 2EJYA 4OEPA 3PDZA 3CH8A 2K20A 3PDVA 2M0UA 3CBZA 2AINA 1X8SA 3GSLA 1D5GA 4P2AB 5DTHA 5E21A 4JORA 1OBYA 1P1DA 1RGRA 2I0LA 4G69A 1IU0A 2OGPA 1QLCA 2D8IA 4NXPA 2EEIA 2L4TA 4NMVA 3QDOA 1TE0A 2PKTA 2OCSA 2FE5A 2L97A 2EHRA 4JOGA 2X7ZA 2W7RA 1N6DA 1UITA 4LMMA 4KFVA 3SUZA 1UM7A 4K72A 2JSNA 3SHWA
chains in the Genus database with same CATH topology
2KOMA 1RGWA 2QKTA 2QKVA 3LNXA 1K32A 1X45A 1IU2A 2KPKA 2DAZA 3QJNA 2WL7A 3RLEA 5ILBA 1ZUBA 3I1EA 2GEFA 2W4FA 3RL8A 1UEWA 2YT8A 3DJ3A 2G5MB 1N7FA 2Z17A 4K76A 3CBYA 4OAJA 1QAVA 2I1NA 5GLJA 1WHDA 2L4SA 2KJPA 2VSPA 1SOZA 5EYZA 1X5QA 4JL7A 4F8KA 5HFFA 2KL1A 2M3MA 3KZDA 4Z8JA 2GZVA 3ZRTA 1V6BA 4NNLA 4IC6A 2JWEA 2M0TA 4GVCA 4GHNA 4JOKA 2ZPMA 2M10A 2EAQA 4FGMA 5E6PB 5D13A 4K75A 1X9ZA 1WFVA 1GQ4A 1GM1A 1WFGA 5F67A 3K50A 2LUIA 4NMPA 2OSGA 2DC2A 1BE9A 2EDZA 2OZFA 4H11A 4Z33A 4N6XA 5GNDA 5E1YA 1TP5A 3MH6A 1T2MA 4E35A 2M0ZA 1WHAA 4NMSA 1M5ZA 4JOHA 5HFBA 4O06A 2KJDA 4JOEA 5IL9A 4NXRA 1UF1A 3R0HA 2MHOA 3GDUA 5HDYA 2D90A 3QO6A 2ENOA 1W9OA 4NMRA 1WF8A 3ID3A 3L4FD 3SOEA 3VQFA 3GCOA 2KAWA 3ID4A 3VQGA 3PS4A 1FC9A 2K1ZA 3CC0A 2VPHA 1OZIA 2VRFA 4JJ3A 4L8NA 3QE1A 4EDJA 2DJTA 5I7ZA 1U37A 4Q2PA 2D92A 2VSVA 4MPAA 1I16A 2DLUA 2H2BA 3HVQC 1UJDA 2V90A 1FC6A 1U3BA 3TSWA 1YBOA 2R4HA 2PA1A 2EEGA 1WI2A 1MFGA 4YYXA 3GJ9A 5HEBA 2KV8A 4Q2OA 5HFEA 1RZXA 1XZ9A 4JOPA 4NNMA 2OMJA 4NMTA 2EGKA 2YUYA 1V62A 5HF1A 4JJ0A 3KHFA 1Z86A 3I18A 3NCVA 3TSZA 4Q2NA 2M0VA 2H3MA 2JREA 1WI4A 2EDVA 2PNTA 1QAVB 2YT7A 1Q3PA 3GDVA 3EGGC 2EXGA 2OPGA 2RCZA 3ID2A 3KZEA 2O2TA 4WYTA 1Q7XA 2LA8A 3EGHC 2F5YA 4FLNA 2DB5A 4RI0A 2DMZA 2KPLA 2QT5A 2I4SA 1R6JA 2R3YA 3MH7A 4P0CA 3RL7A 2EEJA 4NMQA 5B6LA 2JILA 4UU6A 2AWXA 3GDSA 3DJ1A 2VZ5A 2KBSA 3HPKA 3E17A 4UU5A 3PV5A 1TQ3A 2LC6A 3R68A 1MFLA 1OBZA 1W9QA 3QIKA 3JXTA 1FCFA 3AXAA 4Q6HA 3O46A 2Q3GA 1Z87A 2I04A 4E34A 2LC7A 2V1WA 2FNEA 2KG2A 5B42A 2FCFA 3O5NA 3MH4A 2KJKA 2MX6A 4E3BA 4R2ZA 3NGHA 5HFCA 1FC7A 3CS0A 1UJVA 2PZDA 2KOJA 2EDPA 2IWOA 1X5RA 1Y7NA 2KQFA 2E7KA 1N6EA 2KOHA 1KWAA 5E22A 1L6OA 1MC7A 2KA9A 3PV2A 1WG6A 2RRMA 2DKRA 5G1EA 2JXOA 1G9OA 1IHJA 2F0AA 1N99A 4K6YA 5FB8C 1WIFA 3ID1A 1X6DA 2JOAA 1V5LA 2P3WA 2FN5A 3TSVA 2Z9IA 2REYA 1V1TA 4JOFA 5G1DA 3KDKA 1UHPA 1VJ6A 4KFWA 1KY9A 2OQSA 1Y8TA 1V5QA 3CBXA 1P1EA 2I0IA 2Q9VA 2HE4A 2IWQA 2ZPLA 3GGEA 1UM1A 4HOPA 5HF4A 1KEFA 1N6FA 2JIKA 2LOBA 3DIWA 3GABA 1WJLA 4WYUA 3GCNA 3R69A 3I4WA 2AWUA 1U39A 5H3JA 3FY5A 1N7TA 1ZOKA 1N7EA 1OBXA 2H2CA 2UZCA 2IWPA 2EV8A 3QJMA 4NMOA 5EZ0A 4NXQA 2I6VA 5HEDA 2KYLA 2JINA 1VB7A 4AMHA 2VWRA 3OTPA 2EEHA 2HGAA 2YTWA 1QAUA 3BPUA 2IWNA 2DM8A 2PDZA 4Q6SA 2QBWA 2CSSA 1NTEA 1TP3A 4Q3HA 1B8QA 4REYA 1RY4A 2EGNA 4JOJA 1UEQA 1Q3OA 1VCWA 2CSJA 5A2PA 1PDRA 2G2LA 2YUBA 2HE2A 1VAEA 4K78A 4Q2QA 1WF7A 2BYGA 5HFDA 1NF3C 2OS6A 5HJ1A 3SFJA 5E11A 2H3LA 4GVDA 3DORA 2CS5A 3KDGA 3NFKA 4XHVA 3TMHA 3OU0A 2QG1A 2PKUA 1WH1A 1BFEA 3CYYA 3PV4A 1I92A 3NFLA 2QKUA 3QGLA 3WKLA 1U38A 5JXBA 5HEYA 3LNYA 1VA8A 3K1RA 4PQWA 2KRGA 1UEZA 2EGOA 1LCYA 3SHUA 3DJAA 1UFXA 4OEOA 1X5NA 4YDPA 2AWWA 5HETA 3K82A 5FHTA 3STJA 1UEPA 2DLSA 3HPMA 4HOPB 3B76A 1SOTA 1UJUA 5F3XA 3WKMA 1GQ5A 1W9EA 2EJYA 4OEPA 3PDZA 3CH8A 2K20A 3PDVA 2M0UA 3CBZA 2AINA 1X8SA 3GSLA 1D5GA 4P2AB 5DTHA 5E21A 4JORA 1OBYA 1P1DA 1RGRA 2I0LA 4G69A 1IU0A 2OGPA 1QLCA 2D8IA 4NXPA 2EEIA 2L4TA 4NMVA 3QDOA 1TE0A 2PKTA 2OCSA 2FE5A 2L97A 2EHRA 4JOGA 2X7ZA 2W7RA 1N6DA 1UITA 4LMMA 4KFVA 3SUZA 1UM7A 4K72A 2JSNA 3SHWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KOM A;  1RGW A;  2QKT A;  2QKV A;  3LNX A;  1K32 A;  1X45 A;  1IU2 A;  2KPK A;  2DAZ A;  3QJN A;  2WL7 A;  3RLE A;  1ZUB A;  3I1E A;  2W4F A;  3RL8 A;  1UEW A;  2YT8 A;  3DJ3 A;  2G5M B;  1N7F A;  2Z17 A;  4K76 A;  3CBY A;  4OAJ A;  1QAV A;  2I1N A;  5GLJ A;  1WHD A;  2L4S A;  2KJP A;  2VSP A;  1SOZ A;  5EYZ A;  1X5Q A;  4JL7 A;  4F8K A;  5HFF A;  2KL1 A;  2M3M A;  3KZD A;  4Z8J A;  2GZV A;  3ZRT A;  1V6B A;  4NNL A;  4IC6 A;  2JWE A;  2M0T A;  4GVC A;  4GHN A;  4JOK A;  2ZPM A;  2M10 A;  2EAQ A;  4FGM A;  5E6P B;  5D13 A;  4K75 A;  1WFV A;  1GQ4 A;  1GM1 A;  1WFG A;  5F67 A;  3K50 A;  2LUI A;  4NMP A;  2OSG A;  2DC2 A;  1BE9 A;  2EDZ A;  2OZF A;  4H11 A;  4Z33 A;  4N6X A;  5GND A;  5E1Y A;  1TP5 A;  3MH6 A;  1T2M A;  4E35 A;  2M0Z A;  1WHA A;  4NMS A;  1M5Z A;  4JOH A;  5HFB A;  4O06 A;  2KJD A;  4JOE A;  4NXR A;  1UF1 A;  3R0H A;  2MHO A;  3GDU A;  5HDY A;  2D90 A;  3QO6 A;  2ENO A;  1W9O A;  4NMR A;  1WF8 A;  3ID3 A;  3L4F D;  3SOE A;  3VQF A;  3GCO A;  2KAW A;  3ID4 A;  3VQG A;  3PS4 A;  1FC9 A;  2K1Z A;  3CC0 A;  2VPH A;  1OZI A;  2VRF A;  4L8N A;  3QE1 A;  2DJT A;  5I7Z A;  1U37 A;  4Q2P A;  2D92 A;  2VSV A;  4MPA A;  1I16 A;  2DLU A;  2H2B A;  3HVQ C;  1UJD A;  2V90 A;  1FC6 A;  1U3B A;  3TSW A;  1YBO A;  2R4H A;  2PA1 A;  2EEG A;  1WI2 A;  1MFG A;  4YYX A;  3GJ9 A;  5HEB A;  2KV8 A;  4Q2O A;  5HFE A;  1RZX A;  1XZ9 A;  4JOP A;  4NNM A;  2OMJ A;  4NMT A;  2EGK A;  2YUY A;  1V62 A;  5HF1 A;  3KHF A;  1Z86 A;  3I18 A;  3TSZ A;  4Q2N A;  2M0V A;  2H3M A;  2JRE A;  1WI4 A;  2EDV A;  2PNT A;  1QAV B;  2YT7 A;  1Q3P A;  3GDV A;  3EGG C;  2EXG A;  2OPG A;  2RCZ A;  3ID2 A;  3KZE A;  2O2T A;  4WYT A;  1Q7X A;  2LA8 A;  3EGH C;  2F5Y A;  2DB5 A;  4RI0 A;  2DMZ A;  2KPL A;  2QT5 A;  2I4S A;  1R6J A;  2R3Y A;  3MH7 A;  4P0C A;  3RL7 A;  2EEJ A;  4NMQ A;  5B6L A;  2JIL A;  4UU6 A;  2AWX A;  3GDS A;  3DJ1 A;  2VZ5 A;  2KBS A;  3HPK A;  3E17 A;  4UU5 A;  3PV5 A;  1TQ3 A;  2LC6 A;  3R68 A;  1MFL A;  1OBZ A;  1W9Q A;  3QIK A;  3JXT A;  1FCF A;  3AXA A;  4Q6H A;  3O46 A;  2Q3G A;  1Z87 A;  2I04 A;  4E34 A;  2LC7 A;  2V1W A;  2FNE A;  2KG2 A;  2FCF A;  3O5N A;  3MH4 A;  2KJK A;  2MX6 A;  4E3B A;  4R2Z A;  3NGH A;  5HFC A;  1FC7 A;  3CS0 A;  1UJV A;  2PZD A;  2KOJ A;  2EDP A;  2IWO A;  1X5R A;  1Y7N A;  2KQF A;  2E7K A;  1N6E A;  2KOH A;  1KWA A;  5E22 A;  1L6O A;  1MC7 A;  2KA9 A;  3PV2 A;  1WG6 A;  2RRM A;  2DKR A;  5G1E A;  2JXO A;  1G9O A;  1IHJ A;  2F0A A;  1N99 A;  4K6Y A;  5FB8 C;  1WIF A;  3ID1 A;  1X6D A;  2JOA A;  1V5L A;  2P3W A;  2FN5 A;  3TSV A;  2Z9I A;  2REY A;  1V1T A;  4JOF A;  5G1D A;  1UHP A;  1VJ6 A;  4KFW A;  1KY9 A;  2OQS A;  1Y8T A;  1V5Q A;  3CBX A;  1P1E A;  2I0I A;  2Q9V A;  2HE4 A;  2IWQ A;  2ZPL A;  3GGE A;  1UM1 A;  4HOP A;  5HF4 A;  1KEF A;  1N6F A;  2JIK A;  2LOB A;  3DIW A;  1WJL A;  4WYU A;  3GCN A;  3R69 A;  3I4W A;  2AWU A;  1U39 A;  5H3J A;  3FY5 A;  1N7T A;  1ZOK A;  1N7E A;  1OBX A;  2H2C A;  2UZC A;  2IWP A;  2EV8 A;  3QJM A;  4NMO A;  5EZ0 A;  4NXQ A;  2I6V A;  5HED A;  2KYL A;  2JIN A;  1VB7 A;  4AMH A;  2VWR A;  3OTP A;  2EEH A;  2HGA A;  2YTW A;  1QAU A;  3BPU A;  2IWN A;  2DM8 A;  2PDZ A;  4Q6S A;  2QBW A;  2CSS A;  1NTE A;  1TP3 A;  4Q3H A;  1B8Q A;  4REY A;  1RY4 A;  2EGN A;  4JOJ A;  1UEQ A;  1Q3O A;  1VCW A;  2CSJ A;  5A2P A;  1PDR A;  2G2L A;  2YUB A;  2HE2 A;  1VAE A;  4K78 A;  4Q2Q A;  1WF7 A;  2BYG A;  5HFD A;  1NF3 C;  2OS6 A;  5HJ1 A;  3SFJ A;  5E11 A;  2H3L A;  4GVD A;  3DOR A;  2CS5 A;  3NFK A;  4XHV A;  3TMH A;  3OU0 A;  2QG1 A;  2PKU A;  1WH1 A;  1BFE A;  3CYY A;  3PV4 A;  1I92 A;  3NFL A;  2QKU A;  3QGL A;  3WKL A;  1U38 A;  5JXB A;  5HEY A;  3LNY A;  1VA8 A;  3K1R A;  4PQW A;  2KRG A;  1UEZ A;  2EGO A;  1LCY A;  3SHU A;  3DJA A;  1UFX A;  4OEO A;  1X5N A;  4YDP A;  2AWW A;  5HET A;  3K82 A;  5FHT A;  3STJ A;  1UEP A;  2DLS A;  3HPM A;  4HOP B;  3B76 A;  1SOT A;  1UJU A;  5F3X A;  3WKM A;  1GQ5 A;  1W9E A;  2EJY A;  4OEP A;  3PDZ A;  3CH8 A;  2K20 A;  3PDV A;  2M0U A;  3CBZ A;  2AIN A;  1X8S A;  3GSL A;  1D5G A;  4P2A B;  5DTH A;  5E21 A;  4JOR A;  1OBY A;  1P1D A;  1RGR A;  2I0L A;  4G69 A;  1IU0 A;  2OGP A;  1QLC A;  2D8I A;  4NXP A;  2EEI A;  2L4T A;  4NMV A;  3QDO A;  1TE0 A;  2PKT A;  2OCS A;  2FE5 A;  2L97 A;  2EHR A;  4JOG A;  2X7Z A;  2W7R A;  1N6D A;  1UIT A;  4LMM A;  4KFV A;  3SUZ A;  1UM7 A;  4K72 A;  4EDJ A;  3SHW A; 
#chains in the Genus database with same CATH topology
 2KOM A;  1RGW A;  2QKT A;  2QKV A;  3LNX A;  1K32 A;  1X45 A;  1IU2 A;  2KPK A;  2DAZ A;  3QJN A;  2WL7 A;  3RLE A;  5ILB A;  1ZUB A;  3I1E A;  2GEF A;  2W4F A;  3RL8 A;  1UEW A;  2YT8 A;  3DJ3 A;  2G5M B;  1N7F A;  2Z17 A;  4K76 A;  3CBY A;  4OAJ A;  1QAV A;  2I1N A;  5GLJ A;  1WHD A;  2L4S A;  2KJP A;  2VSP A;  1SOZ A;  5EYZ A;  1X5Q A;  4JL7 A;  4F8K A;  5HFF A;  2KL1 A;  2M3M A;  3KZD A;  4Z8J A;  2GZV A;  3ZRT A;  1V6B A;  4NNL A;  4IC6 A;  2JWE A;  2M0T A;  4GVC A;  4GHN A;  4JOK A;  2ZPM A;  2M10 A;  2EAQ A;  4FGM A;  5E6P B;  5D13 A;  4K75 A;  1X9Z A;  1WFV A;  1GQ4 A;  1GM1 A;  1WFG A;  5F67 A;  3K50 A;  2LUI A;  4NMP A;  2OSG A;  2DC2 A;  1BE9 A;  2EDZ A;  2OZF A;  4H11 A;  4Z33 A;  4N6X A;  5GND A;  5E1Y A;  1TP5 A;  3MH6 A;  1T2M A;  4E35 A;  2M0Z A;  1WHA A;  4NMS A;  1M5Z A;  4JOH A;  5HFB A;  4O06 A;  2KJD A;  4JOE A;  5IL9 A;  4NXR A;  1UF1 A;  3R0H A;  2MHO A;  3GDU A;  5HDY A;  2D90 A;  3QO6 A;  2ENO A;  1W9O A;  4NMR A;  1WF8 A;  3ID3 A;  3L4F D;  3SOE A;  3VQF A;  3GCO A;  2KAW A;  3ID4 A;  3VQG A;  3PS4 A;  1FC9 A;  2K1Z A;  3CC0 A;  2VPH A;  1OZI A;  2VRF A;  4JJ3 A;  4L8N A;  3QE1 A;  4EDJ A;  2DJT A;  5I7Z A;  1U37 A;  4Q2P A;  2D92 A;  2VSV A;  4MPA A;  1I16 A;  2DLU A;  2H2B A;  3HVQ C;  1UJD A;  2V90 A;  1FC6 A;  1U3B A;  3TSW A;  1YBO A;  2R4H A;  2PA1 A;  2EEG A;  1WI2 A;  1MFG A;  4YYX A;  3GJ9 A;  5HEB A;  2KV8 A;  4Q2O A;  5HFE A;  1RZX A;  1XZ9 A;  4JOP A;  4NNM A;  2OMJ A;  4NMT A;  2EGK A;  2YUY A;  1V62 A;  5HF1 A;  4JJ0 A;  3KHF A;  1Z86 A;  3I18 A;  3NCV A;  3TSZ A;  4Q2N A;  2M0V A;  2H3M A;  2JRE A;  1WI4 A;  2EDV A;  2PNT A;  1QAV B;  2YT7 A;  1Q3P A;  3GDV A;  3EGG C;  2EXG A;  2OPG A;  2RCZ A;  3ID2 A;  3KZE A;  2O2T A;  4WYT A;  1Q7X A;  2LA8 A;  3EGH C;  2F5Y A;  4FLN A;  2DB5 A;  4RI0 A;  2DMZ A;  2KPL A;  2QT5 A;  2I4S A;  1R6J A;  2R3Y A;  3MH7 A;  4P0C A;  3RL7 A;  2EEJ A;  4NMQ A;  5B6L A;  2JIL A;  4UU6 A;  2AWX A;  3GDS A;  3DJ1 A;  2VZ5 A;  2KBS A;  3HPK A;  3E17 A;  4UU5 A;  3PV5 A;  1TQ3 A;  2LC6 A;  3R68 A;  1MFL A;  1OBZ A;  1W9Q A;  3QIK A;  3JXT A;  1FCF A;  3AXA A;  4Q6H A;  3O46 A;  2Q3G A;  1Z87 A;  2I04 A;  4E34 A;  2LC7 A;  2V1W A;  2FNE A;  2KG2 A;  5B42 A;  2FCF A;  3O5N A;  3MH4 A;  2KJK A;  2MX6 A;  4E3B A;  4R2Z A;  3NGH A;  5HFC A;  1FC7 A;  3CS0 A;  1UJV A;  2PZD A;  2KOJ A;  2EDP A;  2IWO A;  1X5R A;  1Y7N A;  2KQF A;  2E7K A;  1N6E A;  2KOH A;  1KWA A;  5E22 A;  1L6O A;  1MC7 A;  2KA9 A;  3PV2 A;  1WG6 A;  2RRM A;  2DKR A;  5G1E A;  2JXO A;  1G9O A;  1IHJ A;  2F0A A;  1N99 A;  4K6Y A;  5FB8 C;  1WIF A;  3ID1 A;  1X6D A;  2JOA A;  1V5L A;  2P3W A;  2FN5 A;  3TSV A;  2Z9I A;  2REY A;  1V1T A;  4JOF A;  5G1D A;  3KDK A;  1UHP A;  1VJ6 A;  4KFW A;  1KY9 A;  2OQS A;  1Y8T A;  1V5Q A;  3CBX A;  1P1E A;  2I0I A;  2Q9V A;  2HE4 A;  2IWQ A;  2ZPL A;  3GGE A;  1UM1 A;  4HOP A;  5HF4 A;  1KEF A;  1N6F A;  2JIK A;  2LOB A;  3DIW A;  3GAB A;  1WJL A;  4WYU A;  3GCN A;  3R69 A;  3I4W A;  2AWU A;  1U39 A;  5H3J A;  3FY5 A;  1N7T A;  1ZOK A;  1N7E A;  1OBX A;  2H2C A;  2UZC A;  2IWP A;  2EV8 A;  3QJM A;  4NMO A;  5EZ0 A;  4NXQ A;  2I6V A;  5HED A;  2KYL A;  2JIN A;  1VB7 A;  4AMH A;  2VWR A;  3OTP A;  2EEH A;  2HGA A;  2YTW A;  1QAU A;  3BPU A;  2IWN A;  2DM8 A;  2PDZ A;  4Q6S A;  2QBW A;  2CSS A;  1NTE A;  1TP3 A;  4Q3H A;  1B8Q A;  4REY A;  1RY4 A;  2EGN A;  4JOJ A;  1UEQ A;  1Q3O A;  1VCW A;  2CSJ A;  5A2P A;  1PDR A;  2G2L A;  2YUB A;  2HE2 A;  1VAE A;  4K78 A;  4Q2Q A;  1WF7 A;  2BYG A;  5HFD A;  1NF3 C;  2OS6 A;  5HJ1 A;  3SFJ A;  5E11 A;  2H3L A;  4GVD A;  3DOR A;  2CS5 A;  3KDG A;  3NFK A;  4XHV A;  3TMH A;  3OU0 A;  2QG1 A;  2PKU A;  1WH1 A;  1BFE A;  3CYY A;  3PV4 A;  1I92 A;  3NFL A;  2QKU A;  3QGL A;  3WKL A;  1U38 A;  5JXB A;  5HEY A;  3LNY A;  1VA8 A;  3K1R A;  4PQW A;  2KRG A;  1UEZ A;  2EGO A;  1LCY A;  3SHU A;  3DJA A;  1UFX A;  4OEO A;  1X5N A;  4YDP A;  2AWW A;  5HET A;  3K82 A;  5FHT A;  3STJ A;  1UEP A;  2DLS A;  3HPM A;  4HOP B;  3B76 A;  1SOT A;  1UJU A;  5F3X A;  3WKM A;  1GQ5 A;  1W9E A;  2EJY A;  4OEP A;  3PDZ A;  3CH8 A;  2K20 A;  3PDV A;  2M0U A;  3CBZ A;  2AIN A;  1X8S A;  3GSL A;  1D5G A;  4P2A B;  5DTH A;  5E21 A;  4JOR A;  1OBY A;  1P1D A;  1RGR A;  2I0L A;  4G69 A;  1IU0 A;  2OGP A;  1QLC A;  2D8I A;  4NXP A;  2EEI A;  2L4T A;  4NMV A;  3QDO A;  1TE0 A;  2PKT A;  2OCS A;  2FE5 A;  2L97 A;  2EHR A;  4JOG A;  2X7Z A;  2W7R A;  1N6D A;  1UIT A;  4LMM A;  4KFV A;  3SUZ A;  1UM7 A;  4K72 A;  2JSN A;  3SHW A; 
#chains in the Genus database with same CATH homology
 2KOM A;  1RGW A;  2QKT A;  2QKV A;  3LNX A;  1K32 A;  1X45 A;  1IU2 A;  2KPK A;  2DAZ A;  3QJN A;  2WL7 A;  3RLE A;  5ILB A;  1ZUB A;  3I1E A;  2GEF A;  2W4F A;  3RL8 A;  1UEW A;  2YT8 A;  3DJ3 A;  2G5M B;  1N7F A;  2Z17 A;  4K76 A;  3CBY A;  4OAJ A;  1QAV A;  2I1N A;  5GLJ A;  1WHD A;  2L4S A;  2KJP A;  2VSP A;  1SOZ A;  5EYZ A;  1X5Q A;  4JL7 A;  4F8K A;  5HFF A;  2KL1 A;  2M3M A;  3KZD A;  4Z8J A;  2GZV A;  3ZRT A;  1V6B A;  4NNL A;  4IC6 A;  2JWE A;  2M0T A;  4GVC A;  4GHN A;  4JOK A;  2ZPM A;  2M10 A;  2EAQ A;  4FGM A;  5E6P B;  5D13 A;  4K75 A;  1X9Z A;  1WFV A;  1GQ4 A;  1GM1 A;  1WFG A;  5F67 A;  3K50 A;  2LUI A;  4NMP A;  2OSG A;  2DC2 A;  1BE9 A;  2EDZ A;  2OZF A;  4H11 A;  4Z33 A;  4N6X A;  5GND A;  5E1Y A;  1TP5 A;  3MH6 A;  1T2M A;  4E35 A;  2M0Z A;  1WHA A;  4NMS A;  1M5Z A;  4JOH A;  5HFB A;  4O06 A;  2KJD A;  4JOE A;  5IL9 A;  4NXR A;  1UF1 A;  3R0H A;  2MHO A;  3GDU A;  5HDY A;  2D90 A;  3QO6 A;  2ENO A;  1W9O A;  4NMR A;  1WF8 A;  3ID3 A;  3L4F D;  3SOE A;  3VQF A;  3GCO A;  2KAW A;  3ID4 A;  3VQG A;  3PS4 A;  1FC9 A;  2K1Z A;  3CC0 A;  2VPH A;  1OZI A;  2VRF A;  4JJ3 A;  4L8N A;  3QE1 A;  4EDJ A;  2DJT A;  5I7Z A;  1U37 A;  4Q2P A;  2D92 A;  2VSV A;  4MPA A;  1I16 A;  2DLU A;  2H2B A;  3HVQ C;  1UJD A;  2V90 A;  1FC6 A;  1U3B A;  3TSW A;  1YBO A;  2R4H A;  2PA1 A;  2EEG A;  1WI2 A;  1MFG A;  4YYX A;  3GJ9 A;  5HEB A;  2KV8 A;  4Q2O A;  5HFE A;  1RZX A;  1XZ9 A;  4JOP A;  4NNM A;  2OMJ A;  4NMT A;  2EGK A;  2YUY A;  1V62 A;  5HF1 A;  4JJ0 A;  3KHF A;  1Z86 A;  3I18 A;  3NCV A;  3TSZ A;  4Q2N A;  2M0V A;  2H3M A;  2JRE A;  1WI4 A;  2EDV A;  2PNT A;  1QAV B;  2YT7 A;  1Q3P A;  3GDV A;  3EGG C;  2EXG A;  2OPG A;  2RCZ A;  3ID2 A;  3KZE A;  2O2T A;  4WYT A;  1Q7X A;  2LA8 A;  3EGH C;  2F5Y A;  4FLN A;  2DB5 A;  4RI0 A;  2DMZ A;  2KPL A;  2QT5 A;  2I4S A;  1R6J A;  2R3Y A;  3MH7 A;  4P0C A;  3RL7 A;  2EEJ A;  4NMQ A;  5B6L A;  2JIL A;  4UU6 A;  2AWX A;  3GDS A;  3DJ1 A;  2VZ5 A;  2KBS A;  3HPK A;  3E17 A;  4UU5 A;  3PV5 A;  1TQ3 A;  2LC6 A;  3R68 A;  1MFL A;  1OBZ A;  1W9Q A;  3QIK A;  3JXT A;  1FCF A;  3AXA A;  4Q6H A;  3O46 A;  2Q3G A;  1Z87 A;  2I04 A;  4E34 A;  2LC7 A;  2V1W A;  2FNE A;  2KG2 A;  5B42 A;  2FCF A;  3O5N A;  3MH4 A;  2KJK A;  2MX6 A;  4E3B A;  4R2Z A;  3NGH A;  5HFC A;  1FC7 A;  3CS0 A;  1UJV A;  2PZD A;  2KOJ A;  2EDP A;  2IWO A;  1X5R A;  1Y7N A;  2KQF A;  2E7K A;  1N6E A;  2KOH A;  1KWA A;  5E22 A;  1L6O A;  1MC7 A;  2KA9 A;  3PV2 A;  1WG6 A;  2RRM A;  2DKR A;  5G1E A;  2JXO A;  1G9O A;  1IHJ A;  2F0A A;  1N99 A;  4K6Y A;  5FB8 C;  1WIF A;  3ID1 A;  1X6D A;  2JOA A;  1V5L A;  2P3W A;  2FN5 A;  3TSV A;  2Z9I A;  2REY A;  1V1T A;  4JOF A;  5G1D A;  3KDK A;  1UHP A;  1VJ6 A;  4KFW A;  1KY9 A;  2OQS A;  1Y8T A;  1V5Q A;  3CBX A;  1P1E A;  2I0I A;  2Q9V A;  2HE4 A;  2IWQ A;  2ZPL A;  3GGE A;  1UM1 A;  4HOP A;  5HF4 A;  1KEF A;  1N6F A;  2JIK A;  2LOB A;  3DIW A;  3GAB A;  1WJL A;  4WYU A;  3GCN A;  3R69 A;  3I4W A;  2AWU A;  1U39 A;  5H3J A;  3FY5 A;  1N7T A;  1ZOK A;  1N7E A;  1OBX A;  2H2C A;  2UZC A;  2IWP A;  2EV8 A;  3QJM A;  4NMO A;  5EZ0 A;  4NXQ A;  2I6V A;  5HED A;  2KYL A;  2JIN A;  1VB7 A;  4AMH A;  2VWR A;  3OTP A;  2EEH A;  2HGA A;  2YTW A;  1QAU A;  3BPU A;  2IWN A;  2DM8 A;  2PDZ A;  4Q6S A;  2QBW A;  2CSS A;  1NTE A;  1TP3 A;  4Q3H A;  1B8Q A;  4REY A;  1RY4 A;  2EGN A;  4JOJ A;  1UEQ A;  1Q3O A;  1VCW A;  2CSJ A;  5A2P A;  1PDR A;  2G2L A;  2YUB A;  2HE2 A;  1VAE A;  4K78 A;  4Q2Q A;  1WF7 A;  2BYG A;  5HFD A;  1NF3 C;  2OS6 A;  5HJ1 A;  3SFJ A;  5E11 A;  2H3L A;  4GVD A;  3DOR A;  2CS5 A;  3KDG A;  3NFK A;  4XHV A;  3TMH A;  3OU0 A;  2QG1 A;  2PKU A;  1WH1 A;  1BFE A;  3CYY A;  3PV4 A;  1I92 A;  3NFL A;  2QKU A;  3QGL A;  3WKL A;  1U38 A;  5JXB A;  5HEY A;  3LNY A;  1VA8 A;  3K1R A;  4PQW A;  2KRG A;  1UEZ A;  2EGO A;  1LCY A;  3SHU A;  3DJA A;  1UFX A;  4OEO A;  1X5N A;  4YDP A;  2AWW A;  5HET A;  3K82 A;  5FHT A;  3STJ A;  1UEP A;  2DLS A;  3HPM A;  4HOP B;  3B76 A;  1SOT A;  1UJU A;  5F3X A;  3WKM A;  1GQ5 A;  1W9E A;  2EJY A;  4OEP A;  3PDZ A;  3CH8 A;  2K20 A;  3PDV A;  2M0U A;  3CBZ A;  2AIN A;  1X8S A;  3GSL A;  1D5G A;  4P2A B;  5DTH A;  5E21 A;  4JOR A;  1OBY A;  1P1D A;  1RGR A;  2I0L A;  4G69 A;  1IU0 A;  2OGP A;  1QLC A;  2D8I A;  4NXP A;  2EEI A;  2L4T A;  4NMV A;  3QDO A;  1TE0 A;  2PKT A;  2OCS A;  2FE5 A;  2L97 A;  2EHR A;  4JOG A;  2X7Z A;  2W7R A;  1N6D A;  1UIT A;  4LMM A;  4KFV A;  3SUZ A;  1UM7 A;  4K72 A;  2JSN A;  3SHW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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