2M0UA

Complex structure of c-terminal cftr peptide and extended pdz1 domain from nherf1
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
117
structure length
117
Chain Sequence
GIDPFTMLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
pubmed doi rcsb
molecule tags Peptide binding protein/protein binding
source organism Homo sapiens
molecule keywords Na(+)/H(+) exchange regulatory cofactor NHE-RF1
total genus 25
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2012-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17820 PDZ_6 PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 2m0uA00
2L97A 2VWRA 3HPKA 4JOGA 3TSVA 3QGLA 3STJA 2KV8A 2KA9A 1W9OA 2FNEA 2M0UA 3RL8A 4K6YA 3GDSA 2JXOA 2CS5A 1P1DA 1VJ6A 3PDVA 2FN5A 1X8SA 4NMSA 3PDZA 2KOMA 1L6OA 4KFVA 2IWNA 1WH1A 2AINA 3I1EA 1UF1A 2V1WA 2I0IA 4JOEA 4XHVA 2PKUA 2I04A 4E3BA 1Q3PA 1GM1A 3QE1A 3K82A 1N7EA 3BPUA 1FC6A 4NMQA 1WJLA 2EEIA 1X45A 3CC0A 2RCZA 1WG6A 2KRGA 1NTEA 1XZ9A 2K20A 5HETA 4IC6A 4JOHA 4Q2OA 2Q3GA 2R3YA 1VAEA 1FC7A 1GQ5A 3SUZA 1UITA 2CSJA 1I16A 1TP3A 4MPAA 2DB5A 3LNYA 2K1ZA 1KWAA 2EDVA 2PA1A 4HOPA 1RY4A 3GCNA 2I4SA 3GGEA 2ZPMA 2LUIA 3SHUA 3OU0A 3NFLA 4UU6A 1N7FA 3E17A 1SOZA 2PDZA 4Z33A 4R2ZA 2AWWA 2EDZA 2ZPLA 1V62A 2L4SA 5EYZA 2QKUA 1M5ZA 2R4HA 3CH8A 4NXRA 2REYA 4OAJA 3QJNA 2I1NA 4GVCA 2KOHA 1KY9A 2M10A 2PKTA 2DC2A 4EDJA 3ID1A 2Z17A 2VPHA 1ZOKA 1UJUA 3DORA 2Z9IA 2I6VA 2JOAA 3PV2A 1WHDA 3B76A 1PDRA 2OZFA 2W7RA 2EEJA 1OZIA 4F8KA 2DLSA 2KL1A 2JILA 3K1RA 4NNLA 4NNMA 5H3JA 3QIKA 1SOTA 2H2BA 2EDPA 4NMPA 2LA8A 2EV8A 1OBXA 2OPGA 4LMMA 5HJ1A 2KPLA 2X7ZA 2EGKA 2M0TA 1QLCA 3I18A 2KQFA 2EXGA 5HFCA 2YT8A 1BFEA 4YDPA 1IU0A 1X6DA 3JXTA 3NFKA 3WKLA 2OQSA 2EHRA 2QKTA 1LCYA 3QJMA 4JOPA 1WFGA 3L4FD 4JORA 2WL7A 2ENOA 5G1EA 1KEFA 4NXPA 3R68A 2RRMA 3TSWA 2EGNA 1Q3OA 2OCSA 1W9QA 4OEOA 2O2TA 4P0CA 5JXBA 4KFWA 4WYUA 5DTHA 2QBWA 1U39A 2JREA 1I92A 3CBXA 1QAVA 3DIWA 4K78A 3MH4A 1OBYA 1VB7A 3CYYA 1Y8TA 4Q3HA 2QT5A 2KJPA 1W9EA 5F3XA 4P2AB 2KBSA 1MFLA 2G5MB 2KAWA 4K72A 1WI4A 3RL7A 4OEPA 2G2LA 2H2CA 2YTWA 1RGWA 5EZ0A 2HE4A 4E34A 2D92A 3EGHC 1QAUA 3PS4A 4K75A 5I7ZA 4L8NA 4RI0A 2BYGA 4AMHA 1TE0A 2KG2A 2YT7A 5HEBA 4YYXA 4GHNA 5E22A 1D5GA 2DM8A 1UEPA 5B6LA 2IWPA 3ID3A 2PNTA 2JINA 2KJKA 4GVDA 4PQWA 5HF4A 2EAQA 3O46A 2CSSA 2M0VA 3SFJA 2H3LA 5G1DA 2EGOA 5E1YA 1T2MA 4JL7A 2VSPA 1UEQA 3HVQC 1N6DA 2KJDA 1WIFA 2GZVA 1U37A 4K76A 1V6BA 2LOBA 3K50A 4Z8JA 3PV5A 4NMTA 2M0ZA 1U38A 1UM1A 4HOPB 2L4TA 3QO6A 1MC7A 2MHOA 1Y7NA 1BE9A 1G9OA 2OSGA 2EJYA 4H11A 2OS6A 2MX6A 1UFXA 3DJAA 1UHPA 5D13A 2AWXA 4G69A 1X5NA 2Q9VA 2KYLA 2VZ5A 2I0LA 1UJVA 3HPMA 1N7TA 3OTPA 2P3WA 1FCFA 1WF7A 3GDUA 4E35A 1RGRA 1WI2A 3KHFA 2H3MA 3GDVA 4FGMA 1U3BA 2QKVA 4UU5A 2JIKA 2DKRA 1VCWA 3RLEA 5GNDA 3VQFA 1Z87A 5E11A 5HFBA 2EEGA 4NMOA 1N99A 1X5QA 1R6JA 4NMRA 5HEYA 2JWEA 4NXQA 5GLJA 5HF1A 4JOKA 1N6EA 5HEDA 4O06A 1Z86A 5HFFA 5HFDA 2V90A 1B8QA 1TQ3A 3R0HA 3ZRTA 3PV4A 1VA8A 4Q2NA 5HFEA 1RZXA 2D90A 3GCOA 4N6XA 2IWOA 3FY5A 3QDOA 3SHWA 5HDYA 2DLUA 2F5YA 1ZUBA 1V1TA 2QG1A 4Q2QA 4NMVA 2OGPA 1UJDA 2IWQA 3MH7A 5F67A 2D8IA 2DJTA 1FC9A 3TMHA 1GQ4A 3CS0A 2KPKA 2UZCA 3CBZA 3ID4A 3KZEA 1NF3C 4Q2PA 3WKMA 3O5NA 1UEWA 2F0AA 3KZDA 3VQGA 1WHAA 3MH6A 3GSLA 2AWUA 4REYA 1MFGA 2FE5A 1V5QA 1TP5A 5E6PB 3GJ9A 2YUBA 2YUYA 5A2PA 1OBZA 2KOJA 1K32A 2HGAA 1QAVB 4JOJA 3I4WA 2EEHA 2LC6A 1YBOA 1WF8A 1X5RA 1UEZA 2DAZA 3AXAA 3ID2A 1WFVA 3LNXA 4Q6HA 5FHTA 3EGGC 1P1EA 2HE2A 3DJ1A 2VRFA 2LC7A 3DJ3A 1N6FA 2PZDA 3CBYA 4WYTA 1V5LA 1IU2A 1UM7A 2OMJA 2E7KA 4JOFA 3SOEA 3R69A 2DMZA 5E21A 2W4FA 1Q7XA 3NGHA 4Q6SA 2VSVA 5FB8C 1IHJA 2FCFA 2M3MA 3TSZA
chains in the Genus database with same CATH superfamily
2L97A 2VWRA 3HPKA 4JOGA 3TSVA 3QGLA 3STJA 2KV8A 2KA9A 3KDGA 1W9OA 2FNEA 2M0UA 3RL8A 4K6YA 3GDSA 2JXOA 2CS5A 1P1DA 1VJ6A 3PDVA 2FN5A 5B42A 1X8SA 4NMSA 3PDZA 2KOMA 1L6OA 4KFVA 2IWNA 1X9ZA 1WH1A 2AINA 3I1EA 4JJ0A 1UF1A 2V1WA 2I0IA 4JOEA 4XHVA 2PKUA 2I04A 4E3BA 1Q3PA 1GM1A 3QE1A 3K82A 1N7EA 3BPUA 1FC6A 4NMQA 1WJLA 2EEIA 1X45A 3CC0A 2RCZA 1WG6A 2KRGA 1NTEA 1XZ9A 2K20A 5HETA 4IC6A 4JOHA 4Q2OA 2Q3GA 2R3YA 1VAEA 1FC7A 1GQ5A 3SUZA 1UITA 2CSJA 1I16A 1TP3A 4MPAA 2DB5A 3LNYA 2K1ZA 1KWAA 2EDVA 2PA1A 4HOPA 1RY4A 3GCNA 2I4SA 3GGEA 2ZPMA 2LUIA 3SHUA 3OU0A 3NFLA 4UU6A 1N7FA 3E17A 1SOZA 2PDZA 4Z33A 4R2ZA 2AWWA 2EDZA 2ZPLA 1V62A 2L4SA 5EYZA 2QKUA 1M5ZA 2R4HA 3CH8A 4NXRA 2REYA 4OAJA 3QJNA 2I1NA 4GVCA 2KOHA 1KY9A 2M10A 2PKTA 2DC2A 4EDJA 3ID1A 2Z17A 2VPHA 1ZOKA 1UJUA 3DORA 2Z9IA 2I6VA 2JOAA 3PV2A 1WHDA 3B76A 1PDRA 2OZFA 2W7RA 2EEJA 1OZIA 4F8KA 2DLSA 2KL1A 2JILA 3K1RA 4NNLA 4NNMA 5H3JA 3QIKA 1SOTA 2H2BA 2EDPA 4NMPA 2LA8A 2EV8A 1OBXA 2OPGA 4LMMA 5HJ1A 2KPLA 2X7ZA 2EGKA 2M0TA 1QLCA 2GEFA 3I18A 2KQFA 2EXGA 5HFCA 2YT8A 1BFEA 4YDPA 1IU0A 1X6DA 3JXTA 3NFKA 3WKLA 2JSNA 2OQSA 2EHRA 2QKTA 1LCYA 3QJMA 4JOPA 1WFGA 3L4FD 4JORA 2WL7A 2ENOA 5G1EA 1KEFA 4NXPA 3R68A 2RRMA 3TSWA 2EGNA 1Q3OA 3GABA 2OCSA 1W9QA 4OEOA 2O2TA 4P0CA 5JXBA 4KFWA 4WYUA 5DTHA 2QBWA 1U39A 2JREA 1I92A 3CBXA 1QAVA 3DIWA 4K78A 3MH4A 1OBYA 1VB7A 3CYYA 1Y8TA 4Q3HA 2QT5A 2KJPA 1W9EA 5F3XA 4P2AB 2KBSA 1MFLA 2G5MB 2KAWA 4K72A 1WI4A 3RL7A 4OEPA 2G2LA 2H2CA 2YTWA 1RGWA 5EZ0A 2HE4A 4E34A 2D92A 3EGHC 1QAUA 3PS4A 4K75A 5I7ZA 4L8NA 4RI0A 2BYGA 4AMHA 1TE0A 2KG2A 2YT7A 5HEBA 4YYXA 5ILBA 4GHNA 5E22A 3NCVA 1D5GA 2DM8A 1UEPA 5B6LA 2IWPA 3ID3A 2PNTA 2JINA 2KJKA 4GVDA 4PQWA 5HF4A 2EAQA 3O46A 2CSSA 2M0VA 3SFJA 2H3LA 5G1DA 2EGOA 5E1YA 1T2MA 4JL7A 2VSPA 1UEQA 3HVQC 1N6DA 2KJDA 1WIFA 2GZVA 1U37A 4K76A 1V6BA 2LOBA 3K50A 4Z8JA 3PV5A 4NMTA 2M0ZA 1U38A 1UM1A 4HOPB 2L4TA 3QO6A 1MC7A 2MHOA 1Y7NA 1BE9A 1G9OA 2OSGA 2EJYA 4H11A 2OS6A 2MX6A 1UFXA 3DJAA 1UHPA 5D13A 2AWXA 4G69A 1X5NA 2Q9VA 2KYLA 2VZ5A 2I0LA 1UJVA 5IL9A 3HPMA 1N7TA 3OTPA 2P3WA 1FCFA 1WF7A 3GDUA 4E35A 1RGRA 1WI2A 3KHFA 2H3MA 3GDVA 4FGMA 1U3BA 2QKVA 4UU5A 2JIKA 2DKRA 1VCWA 3RLEA 5GNDA 3VQFA 1Z87A 5E11A 5HFBA 2EEGA 4NMOA 1N99A 1X5QA 1R6JA 4NMRA 5HEYA 2JWEA 4NXQA 5GLJA 5HF1A 4JOKA 1N6EA 5HEDA 4O06A 1Z86A 5HFFA 5HFDA 2V90A 1B8QA 3KDKA 1TQ3A 3R0HA 3ZRTA 3PV4A 1VA8A 4Q2NA 5HFEA 1RZXA 2D90A 3GCOA 4N6XA 2IWOA 3FY5A 3QDOA 3SHWA 5HDYA 2DLUA 2F5YA 1ZUBA 1V1TA 2QG1A 4Q2QA 4NMVA 2OGPA 1UJDA 2IWQA 3MH7A 5F67A 2D8IA 2DJTA 1FC9A 3TMHA 1GQ4A 3CS0A 2KPKA 2UZCA 3CBZA 3ID4A 3KZEA 1NF3C 4Q2PA 3WKMA 3O5NA 1UEWA 2F0AA 3KZDA 3VQGA 1WHAA 3MH6A 3GSLA 2AWUA 4REYA 1MFGA 2FE5A 1V5QA 1TP5A 5E6PB 3GJ9A 2YUBA 2YUYA 5A2PA 1OBZA 2KOJA 1K32A 2HGAA 1QAVB 4JOJA 3I4WA 2EEHA 2LC6A 1YBOA 1WF8A 1X5RA 1UEZA 2DAZA 3AXAA 3ID2A 1WFVA 3LNXA 4Q6HA 5FHTA 3EGGC 1P1EA 2HE2A 3DJ1A 2VRFA 2LC7A 3DJ3A 4FLNA 1N6FA 2PZDA 3CBYA 4WYTA 1V5LA 1IU2A 1UM7A 2OMJA 2E7KA 4JOFA 3SOEA 3R69A 2DMZA 5E21A 2W4FA 1Q7XA 3NGHA 4Q6SA 2VSVA 4JJ3A 5FB8C 1IHJA 2FCFA 2M3MA 3TSZA
chains in the Genus database with same CATH topology
2L97A 2VWRA 3HPKA 4JOGA 3TSVA 3QGLA 3STJA 2KV8A 2KA9A 3KDGA 1W9OA 2FNEA 2M0UA 3RL8A 4K6YA 3GDSA 2JXOA 2CS5A 1P1DA 1VJ6A 3PDVA 2FN5A 5B42A 1X8SA 4NMSA 3PDZA 2KOMA 1L6OA 4KFVA 2IWNA 1X9ZA 1WH1A 2AINA 3I1EA 4JJ0A 1UF1A 2V1WA 2I0IA 4JOEA 4XHVA 2PKUA 2I04A 4E3BA 1Q3PA 1GM1A 3QE1A 3K82A 1N7EA 3BPUA 1FC6A 4NMQA 1WJLA 2EEIA 1X45A 3CC0A 2RCZA 1WG6A 2KRGA 1NTEA 1XZ9A 2K20A 5HETA 4IC6A 4JOHA 4Q2OA 2Q3GA 2R3YA 1VAEA 1FC7A 1GQ5A 3SUZA 1UITA 2CSJA 1I16A 1TP3A 4MPAA 2DB5A 3LNYA 2K1ZA 1KWAA 2EDVA 2PA1A 4HOPA 1RY4A 3GCNA 2I4SA 3GGEA 2ZPMA 2LUIA 3SHUA 3OU0A 3NFLA 4UU6A 1N7FA 3E17A 1SOZA 2PDZA 4Z33A 4R2ZA 2AWWA 2EDZA 2ZPLA 1V62A 2L4SA 5EYZA 2QKUA 1M5ZA 2R4HA 3CH8A 4NXRA 2REYA 4OAJA 3QJNA 2I1NA 4GVCA 2KOHA 1KY9A 2M10A 2PKTA 2DC2A 4EDJA 3ID1A 2Z17A 2VPHA 1ZOKA 1UJUA 3DORA 2Z9IA 2I6VA 2JOAA 3PV2A 1WHDA 3B76A 1PDRA 2OZFA 2W7RA 2EEJA 1OZIA 4F8KA 2DLSA 2KL1A 2JILA 3K1RA 4NNLA 4NNMA 5H3JA 3QIKA 1SOTA 2H2BA 2EDPA 4NMPA 2LA8A 2EV8A 1OBXA 2OPGA 4LMMA 5HJ1A 2KPLA 2X7ZA 2EGKA 2M0TA 1QLCA 2GEFA 3I18A 2KQFA 2EXGA 5HFCA 2YT8A 1BFEA 4YDPA 1IU0A 1X6DA 3JXTA 3NFKA 3WKLA 2JSNA 2OQSA 2EHRA 2QKTA 1LCYA 3QJMA 4JOPA 1WFGA 3L4FD 4JORA 2WL7A 2ENOA 5G1EA 1KEFA 4NXPA 3R68A 2RRMA 3TSWA 2EGNA 1Q3OA 3GABA 2OCSA 1W9QA 4OEOA 2O2TA 4P0CA 5JXBA 4KFWA 4WYUA 5DTHA 2QBWA 1U39A 2JREA 1I92A 3CBXA 1QAVA 3DIWA 4K78A 3MH4A 1OBYA 1VB7A 3CYYA 1Y8TA 4Q3HA 2QT5A 2KJPA 1W9EA 5F3XA 4P2AB 2KBSA 1MFLA 2G5MB 2KAWA 4K72A 1WI4A 3RL7A 4OEPA 2G2LA 2H2CA 2YTWA 1RGWA 5EZ0A 2HE4A 4E34A 2D92A 3EGHC 1QAUA 3PS4A 4K75A 5I7ZA 4L8NA 4RI0A 2BYGA 4AMHA 1TE0A 2KG2A 2YT7A 5HEBA 4YYXA 5ILBA 4GHNA 5E22A 3NCVA 1D5GA 2DM8A 1UEPA 5B6LA 2IWPA 3ID3A 2PNTA 2JINA 2KJKA 4GVDA 4PQWA 5HF4A 2EAQA 3O46A 2CSSA 2M0VA 3SFJA 2H3LA 5G1DA 2EGOA 5E1YA 1T2MA 4JL7A 2VSPA 1UEQA 3HVQC 1N6DA 2KJDA 1WIFA 2GZVA 1U37A 4K76A 1V6BA 2LOBA 3K50A 4Z8JA 3PV5A 4NMTA 2M0ZA 1U38A 1UM1A 4HOPB 2L4TA 3QO6A 1MC7A 2MHOA 1Y7NA 1BE9A 1G9OA 2OSGA 2EJYA 4H11A 2OS6A 2MX6A 1UFXA 3DJAA 1UHPA 5D13A 2AWXA 4G69A 1X5NA 2Q9VA 2KYLA 2VZ5A 2I0LA 1UJVA 5IL9A 3HPMA 1N7TA 3OTPA 2P3WA 1FCFA 1WF7A 3GDUA 4E35A 1RGRA 1WI2A 3KHFA 2H3MA 3GDVA 4FGMA 1U3BA 2QKVA 4UU5A 2JIKA 2DKRA 1VCWA 3RLEA 5GNDA 3VQFA 1Z87A 5E11A 5HFBA 2EEGA 4NMOA 1N99A 1X5QA 1R6JA 4NMRA 5HEYA 2JWEA 4NXQA 5GLJA 5HF1A 4JOKA 1N6EA 5HEDA 4O06A 1Z86A 5HFFA 5HFDA 2V90A 1B8QA 3KDKA 1TQ3A 3R0HA 3ZRTA 3PV4A 1VA8A 4Q2NA 5HFEA 1RZXA 2D90A 3GCOA 4N6XA 2IWOA 3FY5A 3QDOA 3SHWA 5HDYA 2DLUA 2F5YA 1ZUBA 1V1TA 2QG1A 4Q2QA 4NMVA 2OGPA 1UJDA 2IWQA 3MH7A 5F67A 2D8IA 2DJTA 1FC9A 3TMHA 1GQ4A 3CS0A 2KPKA 2UZCA 3CBZA 3ID4A 3KZEA 1NF3C 4Q2PA 3WKMA 3O5NA 1UEWA 2F0AA 3KZDA 3VQGA 1WHAA 3MH6A 3GSLA 2AWUA 4REYA 1MFGA 2FE5A 1V5QA 1TP5A 5E6PB 3GJ9A 2YUBA 2YUYA 5A2PA 1OBZA 2KOJA 1K32A 2HGAA 1QAVB 4JOJA 3I4WA 2EEHA 2LC6A 1YBOA 1WF8A 1X5RA 1UEZA 2DAZA 3AXAA 3ID2A 1WFVA 3LNXA 4Q6HA 5FHTA 3EGGC 1P1EA 2HE2A 3DJ1A 2VRFA 2LC7A 3DJ3A 4FLNA 1N6FA 2PZDA 3CBYA 4WYTA 1V5LA 1IU2A 1UM7A 2OMJA 2E7KA 4JOFA 3SOEA 3R69A 2DMZA 5E21A 2W4FA 1Q7XA 3NGHA 4Q6SA 2VSVA 4JJ3A 5FB8C 1IHJA 2FCFA 2M3MA 3TSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L97 A;  2VWR A;  3HPK A;  4JOG A;  3TSV A;  3QGL A;  3STJ A;  2KV8 A;  2KA9 A;  1W9O A;  2FNE A;  2M0U A;  3RL8 A;  4K6Y A;  3GDS A;  2JXO A;  2CS5 A;  1P1D A;  1VJ6 A;  3PDV A;  2FN5 A;  1X8S A;  4NMS A;  3PDZ A;  2KOM A;  1L6O A;  4KFV A;  2IWN A;  1WH1 A;  2AIN A;  3I1E A;  1UF1 A;  2V1W A;  2I0I A;  4JOE A;  4XHV A;  2PKU A;  2I04 A;  4E3B A;  1Q3P A;  1GM1 A;  3QE1 A;  3K82 A;  1N7E A;  3BPU A;  1FC6 A;  4NMQ A;  1WJL A;  2EEI A;  1X45 A;  3CC0 A;  2RCZ A;  1WG6 A;  2KRG A;  1NTE A;  1XZ9 A;  2K20 A;  5HET A;  4IC6 A;  4JOH A;  4Q2O A;  2Q3G A;  2R3Y A;  1VAE A;  1FC7 A;  1GQ5 A;  3SUZ A;  1UIT A;  2CSJ A;  1I16 A;  1TP3 A;  4MPA A;  2DB5 A;  3LNY A;  2K1Z A;  1KWA A;  2EDV A;  2PA1 A;  4HOP A;  1RY4 A;  3GCN A;  2I4S A;  3GGE A;  2ZPM A;  2LUI A;  3SHU A;  3OU0 A;  3NFL A;  4UU6 A;  1N7F A;  3E17 A;  1SOZ A;  2PDZ A;  4Z33 A;  4R2Z A;  2AWW A;  2EDZ A;  2ZPL A;  1V62 A;  2L4S A;  5EYZ A;  2QKU A;  1M5Z A;  2R4H A;  3CH8 A;  4NXR A;  2REY A;  4OAJ A;  3QJN A;  2I1N A;  4GVC A;  2KOH A;  1KY9 A;  2M10 A;  2PKT A;  2DC2 A;  4EDJ A;  3ID1 A;  2Z17 A;  2VPH A;  1ZOK A;  1UJU A;  3DOR A;  2Z9I A;  2I6V A;  2JOA A;  3PV2 A;  1WHD A;  3B76 A;  1PDR A;  2OZF A;  2W7R A;  2EEJ A;  1OZI A;  4F8K A;  2DLS A;  2KL1 A;  2JIL A;  3K1R A;  4NNL A;  4NNM A;  5H3J A;  3QIK A;  1SOT A;  2H2B A;  2EDP A;  4NMP A;  2LA8 A;  2EV8 A;  1OBX A;  2OPG A;  4LMM A;  5HJ1 A;  2KPL A;  2X7Z A;  2EGK A;  2M0T A;  1QLC A;  3I18 A;  2KQF A;  2EXG A;  5HFC A;  2YT8 A;  1BFE A;  4YDP A;  1IU0 A;  1X6D A;  3JXT A;  3NFK A;  3WKL A;  2OQS A;  2EHR A;  2QKT A;  1LCY A;  3QJM A;  4JOP A;  1WFG A;  3L4F D;  4JOR A;  2WL7 A;  2ENO A;  5G1E A;  1KEF A;  4NXP A;  3R68 A;  2RRM A;  3TSW A;  2EGN A;  1Q3O A;  2OCS A;  1W9Q A;  4OEO A;  2O2T A;  4P0C A;  5JXB A;  4KFW A;  4WYU A;  5DTH A;  2QBW A;  1U39 A;  2JRE A;  1I92 A;  3CBX A;  1QAV A;  3DIW A;  4K78 A;  3MH4 A;  1OBY A;  1VB7 A;  3CYY A;  1Y8T A;  4Q3H A;  2QT5 A;  2KJP A;  1W9E A;  5F3X A;  4P2A B;  2KBS A;  1MFL A;  2G5M B;  2KAW A;  4K72 A;  1WI4 A;  3RL7 A;  4OEP A;  2G2L A;  2H2C A;  2YTW A;  1RGW A;  5EZ0 A;  2HE4 A;  4E34 A;  2D92 A;  3EGH C;  1QAU A;  3PS4 A;  4K75 A;  5I7Z A;  4L8N A;  4RI0 A;  2BYG A;  4AMH A;  1TE0 A;  2KG2 A;  2YT7 A;  5HEB A;  4YYX A;  4GHN A;  5E22 A;  1D5G A;  2DM8 A;  1UEP A;  5B6L A;  2IWP A;  3ID3 A;  2PNT A;  2JIN A;  2KJK A;  4GVD A;  4PQW A;  5HF4 A;  2EAQ A;  3O46 A;  2CSS A;  2M0V A;  3SFJ A;  2H3L A;  5G1D A;  2EGO A;  5E1Y A;  1T2M A;  4JL7 A;  2VSP A;  1UEQ A;  3HVQ C;  1N6D A;  2KJD A;  1WIF A;  2GZV A;  1U37 A;  4K76 A;  1V6B A;  2LOB A;  3K50 A;  4Z8J A;  3PV5 A;  4NMT A;  2M0Z A;  1U38 A;  1UM1 A;  4HOP B;  2L4T A;  3QO6 A;  1MC7 A;  2MHO A;  1Y7N A;  1BE9 A;  1G9O A;  2OSG A;  2EJY A;  4H11 A;  2OS6 A;  2MX6 A;  1UFX A;  3DJA A;  1UHP A;  5D13 A;  2AWX A;  4G69 A;  1X5N A;  2Q9V A;  2KYL A;  2VZ5 A;  2I0L A;  1UJV A;  3HPM A;  1N7T A;  3OTP A;  2P3W A;  1FCF A;  1WF7 A;  3GDU A;  4E35 A;  1RGR A;  1WI2 A;  3KHF A;  2H3M A;  3GDV A;  4FGM A;  1U3B A;  2QKV A;  4UU5 A;  2JIK A;  2DKR A;  1VCW A;  3RLE A;  5GND A;  3VQF A;  1Z87 A;  5E11 A;  5HFB A;  2EEG A;  4NMO A;  1N99 A;  1X5Q A;  1R6J A;  4NMR A;  5HEY A;  2JWE A;  4NXQ A;  5GLJ A;  5HF1 A;  4JOK A;  1N6E A;  5HED A;  4O06 A;  1Z86 A;  5HFF A;  5HFD A;  2V90 A;  1B8Q A;  1TQ3 A;  3R0H A;  3ZRT A;  3PV4 A;  1VA8 A;  4Q2N A;  5HFE A;  1RZX A;  2D90 A;  3GCO A;  4N6X A;  2IWO A;  3FY5 A;  3QDO A;  3SHW A;  5HDY A;  2DLU A;  2F5Y A;  1ZUB A;  1V1T A;  2QG1 A;  4Q2Q A;  4NMV A;  2OGP A;  1UJD A;  2IWQ A;  3MH7 A;  5F67 A;  2D8I A;  2DJT A;  1FC9 A;  3TMH A;  1GQ4 A;  3CS0 A;  2KPK A;  2UZC A;  3CBZ A;  3ID4 A;  3KZE A;  1NF3 C;  4Q2P A;  3WKM A;  3O5N A;  1UEW A;  2F0A A;  3KZD A;  3VQG A;  1WHA A;  3MH6 A;  3GSL A;  2AWU A;  4REY A;  1MFG A;  2FE5 A;  1V5Q A;  1TP5 A;  5E6P B;  3GJ9 A;  2YUB A;  2YUY A;  5A2P A;  1OBZ A;  2KOJ A;  1K32 A;  2HGA A;  1QAV B;  4JOJ A;  3I4W A;  2EEH A;  2LC6 A;  1YBO A;  1WF8 A;  1X5R A;  1UEZ A;  2DAZ A;  3AXA A;  3ID2 A;  1WFV A;  3LNX A;  4Q6H A;  5FHT A;  3EGG C;  1P1E A;  2HE2 A;  3DJ1 A;  2VRF A;  2LC7 A;  3DJ3 A;  1N6F A;  2PZD A;  3CBY A;  4WYT A;  1V5L A;  1IU2 A;  1UM7 A;  2OMJ A;  2E7K A;  4JOF A;  3SOE A;  3R69 A;  2DMZ A;  5E21 A;  2W4F A;  1Q7X A;  3NGH A;  4Q6S A;  2VSV A;  5FB8 C;  1IHJ A;  2FCF A;  2M3M A;  3TSZ A; 
#chains in the Genus database with same CATH topology
 2L97 A;  2VWR A;  3HPK A;  4JOG A;  3TSV A;  3QGL A;  3STJ A;  2KV8 A;  2KA9 A;  3KDG A;  1W9O A;  2FNE A;  2M0U A;  3RL8 A;  4K6Y A;  3GDS A;  2JXO A;  2CS5 A;  1P1D A;  1VJ6 A;  3PDV A;  2FN5 A;  5B42 A;  1X8S A;  4NMS A;  3PDZ A;  2KOM A;  1L6O A;  4KFV A;  2IWN A;  1X9Z A;  1WH1 A;  2AIN A;  3I1E A;  4JJ0 A;  1UF1 A;  2V1W A;  2I0I A;  4JOE A;  4XHV A;  2PKU A;  2I04 A;  4E3B A;  1Q3P A;  1GM1 A;  3QE1 A;  3K82 A;  1N7E A;  3BPU A;  1FC6 A;  4NMQ A;  1WJL A;  2EEI A;  1X45 A;  3CC0 A;  2RCZ A;  1WG6 A;  2KRG A;  1NTE A;  1XZ9 A;  2K20 A;  5HET A;  4IC6 A;  4JOH A;  4Q2O A;  2Q3G A;  2R3Y A;  1VAE A;  1FC7 A;  1GQ5 A;  3SUZ A;  1UIT A;  2CSJ A;  1I16 A;  1TP3 A;  4MPA A;  2DB5 A;  3LNY A;  2K1Z A;  1KWA A;  2EDV A;  2PA1 A;  4HOP A;  1RY4 A;  3GCN A;  2I4S A;  3GGE A;  2ZPM A;  2LUI A;  3SHU A;  3OU0 A;  3NFL A;  4UU6 A;  1N7F A;  3E17 A;  1SOZ A;  2PDZ A;  4Z33 A;  4R2Z A;  2AWW A;  2EDZ A;  2ZPL A;  1V62 A;  2L4S A;  5EYZ A;  2QKU A;  1M5Z A;  2R4H A;  3CH8 A;  4NXR A;  2REY A;  4OAJ A;  3QJN A;  2I1N A;  4GVC A;  2KOH A;  1KY9 A;  2M10 A;  2PKT A;  2DC2 A;  4EDJ A;  3ID1 A;  2Z17 A;  2VPH A;  1ZOK A;  1UJU A;  3DOR A;  2Z9I A;  2I6V A;  2JOA A;  3PV2 A;  1WHD A;  3B76 A;  1PDR A;  2OZF A;  2W7R A;  2EEJ A;  1OZI A;  4F8K A;  2DLS A;  2KL1 A;  2JIL A;  3K1R A;  4NNL A;  4NNM A;  5H3J A;  3QIK A;  1SOT A;  2H2B A;  2EDP A;  4NMP A;  2LA8 A;  2EV8 A;  1OBX A;  2OPG A;  4LMM A;  5HJ1 A;  2KPL A;  2X7Z A;  2EGK A;  2M0T A;  1QLC A;  2GEF A;  3I18 A;  2KQF A;  2EXG A;  5HFC A;  2YT8 A;  1BFE A;  4YDP A;  1IU0 A;  1X6D A;  3JXT A;  3NFK A;  3WKL A;  2JSN A;  2OQS A;  2EHR A;  2QKT A;  1LCY A;  3QJM A;  4JOP A;  1WFG A;  3L4F D;  4JOR A;  2WL7 A;  2ENO A;  5G1E A;  1KEF A;  4NXP A;  3R68 A;  2RRM A;  3TSW A;  2EGN A;  1Q3O A;  3GAB A;  2OCS A;  1W9Q A;  4OEO A;  2O2T A;  4P0C A;  5JXB A;  4KFW A;  4WYU A;  5DTH A;  2QBW A;  1U39 A;  2JRE A;  1I92 A;  3CBX A;  1QAV A;  3DIW A;  4K78 A;  3MH4 A;  1OBY A;  1VB7 A;  3CYY A;  1Y8T A;  4Q3H A;  2QT5 A;  2KJP A;  1W9E A;  5F3X A;  4P2A B;  2KBS A;  1MFL A;  2G5M B;  2KAW A;  4K72 A;  1WI4 A;  3RL7 A;  4OEP A;  2G2L A;  2H2C A;  2YTW A;  1RGW A;  5EZ0 A;  2HE4 A;  4E34 A;  2D92 A;  3EGH C;  1QAU A;  3PS4 A;  4K75 A;  5I7Z A;  4L8N A;  4RI0 A;  2BYG A;  4AMH A;  1TE0 A;  2KG2 A;  2YT7 A;  5HEB A;  4YYX A;  5ILB A;  4GHN A;  5E22 A;  3NCV A;  1D5G A;  2DM8 A;  1UEP A;  5B6L A;  2IWP A;  3ID3 A;  2PNT A;  2JIN A;  2KJK A;  4GVD A;  4PQW A;  5HF4 A;  2EAQ A;  3O46 A;  2CSS A;  2M0V A;  3SFJ A;  2H3L A;  5G1D A;  2EGO A;  5E1Y A;  1T2M A;  4JL7 A;  2VSP A;  1UEQ A;  3HVQ C;  1N6D A;  2KJD A;  1WIF A;  2GZV A;  1U37 A;  4K76 A;  1V6B A;  2LOB A;  3K50 A;  4Z8J A;  3PV5 A;  4NMT A;  2M0Z A;  1U38 A;  1UM1 A;  4HOP B;  2L4T A;  3QO6 A;  1MC7 A;  2MHO A;  1Y7N A;  1BE9 A;  1G9O A;  2OSG A;  2EJY A;  4H11 A;  2OS6 A;  2MX6 A;  1UFX A;  3DJA A;  1UHP A;  5D13 A;  2AWX A;  4G69 A;  1X5N A;  2Q9V A;  2KYL A;  2VZ5 A;  2I0L A;  1UJV A;  5IL9 A;  3HPM A;  1N7T A;  3OTP A;  2P3W A;  1FCF A;  1WF7 A;  3GDU A;  4E35 A;  1RGR A;  1WI2 A;  3KHF A;  2H3M A;  3GDV A;  4FGM A;  1U3B A;  2QKV A;  4UU5 A;  2JIK A;  2DKR A;  1VCW A;  3RLE A;  5GND A;  3VQF A;  1Z87 A;  5E11 A;  5HFB A;  2EEG A;  4NMO A;  1N99 A;  1X5Q A;  1R6J A;  4NMR A;  5HEY A;  2JWE A;  4NXQ A;  5GLJ A;  5HF1 A;  4JOK A;  1N6E A;  5HED A;  4O06 A;  1Z86 A;  5HFF A;  5HFD A;  2V90 A;  1B8Q A;  3KDK A;  1TQ3 A;  3R0H A;  3ZRT A;  3PV4 A;  1VA8 A;  4Q2N A;  5HFE A;  1RZX A;  2D90 A;  3GCO A;  4N6X A;  2IWO A;  3FY5 A;  3QDO A;  3SHW A;  5HDY A;  2DLU A;  2F5Y A;  1ZUB A;  1V1T A;  2QG1 A;  4Q2Q A;  4NMV A;  2OGP A;  1UJD A;  2IWQ A;  3MH7 A;  5F67 A;  2D8I A;  2DJT A;  1FC9 A;  3TMH A;  1GQ4 A;  3CS0 A;  2KPK A;  2UZC A;  3CBZ A;  3ID4 A;  3KZE A;  1NF3 C;  4Q2P A;  3WKM A;  3O5N A;  1UEW A;  2F0A A;  3KZD A;  3VQG A;  1WHA A;  3MH6 A;  3GSL A;  2AWU A;  4REY A;  1MFG A;  2FE5 A;  1V5Q A;  1TP5 A;  5E6P B;  3GJ9 A;  2YUB A;  2YUY A;  5A2P A;  1OBZ A;  2KOJ A;  1K32 A;  2HGA A;  1QAV B;  4JOJ A;  3I4W A;  2EEH A;  2LC6 A;  1YBO A;  1WF8 A;  1X5R A;  1UEZ A;  2DAZ A;  3AXA A;  3ID2 A;  1WFV A;  3LNX A;  4Q6H A;  5FHT A;  3EGG C;  1P1E A;  2HE2 A;  3DJ1 A;  2VRF A;  2LC7 A;  3DJ3 A;  4FLN A;  1N6F A;  2PZD A;  3CBY A;  4WYT A;  1V5L A;  1IU2 A;  1UM7 A;  2OMJ A;  2E7K A;  4JOF A;  3SOE A;  3R69 A;  2DMZ A;  5E21 A;  2W4F A;  1Q7X A;  3NGH A;  4Q6S A;  2VSV A;  4JJ3 A;  5FB8 C;  1IHJ A;  2FCF A;  2M3M A;  3TSZ A; 
#chains in the Genus database with same CATH homology
 2L97 A;  2VWR A;  3HPK A;  4JOG A;  3TSV A;  3QGL A;  3STJ A;  2KV8 A;  2KA9 A;  3KDG A;  1W9O A;  2FNE A;  2M0U A;  3RL8 A;  4K6Y A;  3GDS A;  2JXO A;  2CS5 A;  1P1D A;  1VJ6 A;  3PDV A;  2FN5 A;  5B42 A;  1X8S A;  4NMS A;  3PDZ A;  2KOM A;  1L6O A;  4KFV A;  2IWN A;  1X9Z A;  1WH1 A;  2AIN A;  3I1E A;  4JJ0 A;  1UF1 A;  2V1W A;  2I0I A;  4JOE A;  4XHV A;  2PKU A;  2I04 A;  4E3B A;  1Q3P A;  1GM1 A;  3QE1 A;  3K82 A;  1N7E A;  3BPU A;  1FC6 A;  4NMQ A;  1WJL A;  2EEI A;  1X45 A;  3CC0 A;  2RCZ A;  1WG6 A;  2KRG A;  1NTE A;  1XZ9 A;  2K20 A;  5HET A;  4IC6 A;  4JOH A;  4Q2O A;  2Q3G A;  2R3Y A;  1VAE A;  1FC7 A;  1GQ5 A;  3SUZ A;  1UIT A;  2CSJ A;  1I16 A;  1TP3 A;  4MPA A;  2DB5 A;  3LNY A;  2K1Z A;  1KWA A;  2EDV A;  2PA1 A;  4HOP A;  1RY4 A;  3GCN A;  2I4S A;  3GGE A;  2ZPM A;  2LUI A;  3SHU A;  3OU0 A;  3NFL A;  4UU6 A;  1N7F A;  3E17 A;  1SOZ A;  2PDZ A;  4Z33 A;  4R2Z A;  2AWW A;  2EDZ A;  2ZPL A;  1V62 A;  2L4S A;  5EYZ A;  2QKU A;  1M5Z A;  2R4H A;  3CH8 A;  4NXR A;  2REY A;  4OAJ A;  3QJN A;  2I1N A;  4GVC A;  2KOH A;  1KY9 A;  2M10 A;  2PKT A;  2DC2 A;  4EDJ A;  3ID1 A;  2Z17 A;  2VPH A;  1ZOK A;  1UJU A;  3DOR A;  2Z9I A;  2I6V A;  2JOA A;  3PV2 A;  1WHD A;  3B76 A;  1PDR A;  2OZF A;  2W7R A;  2EEJ A;  1OZI A;  4F8K A;  2DLS A;  2KL1 A;  2JIL A;  3K1R A;  4NNL A;  4NNM A;  5H3J A;  3QIK A;  1SOT A;  2H2B A;  2EDP A;  4NMP A;  2LA8 A;  2EV8 A;  1OBX A;  2OPG A;  4LMM A;  5HJ1 A;  2KPL A;  2X7Z A;  2EGK A;  2M0T A;  1QLC A;  2GEF A;  3I18 A;  2KQF A;  2EXG A;  5HFC A;  2YT8 A;  1BFE A;  4YDP A;  1IU0 A;  1X6D A;  3JXT A;  3NFK A;  3WKL A;  2JSN A;  2OQS A;  2EHR A;  2QKT A;  1LCY A;  3QJM A;  4JOP A;  1WFG A;  3L4F D;  4JOR A;  2WL7 A;  2ENO A;  5G1E A;  1KEF A;  4NXP A;  3R68 A;  2RRM A;  3TSW A;  2EGN A;  1Q3O A;  3GAB A;  2OCS A;  1W9Q A;  4OEO A;  2O2T A;  4P0C A;  5JXB A;  4KFW A;  4WYU A;  5DTH A;  2QBW A;  1U39 A;  2JRE A;  1I92 A;  3CBX A;  1QAV A;  3DIW A;  4K78 A;  3MH4 A;  1OBY A;  1VB7 A;  3CYY A;  1Y8T A;  4Q3H A;  2QT5 A;  2KJP A;  1W9E A;  5F3X A;  4P2A B;  2KBS A;  1MFL A;  2G5M B;  2KAW A;  4K72 A;  1WI4 A;  3RL7 A;  4OEP A;  2G2L A;  2H2C A;  2YTW A;  1RGW A;  5EZ0 A;  2HE4 A;  4E34 A;  2D92 A;  3EGH C;  1QAU A;  3PS4 A;  4K75 A;  5I7Z A;  4L8N A;  4RI0 A;  2BYG A;  4AMH A;  1TE0 A;  2KG2 A;  2YT7 A;  5HEB A;  4YYX A;  5ILB A;  4GHN A;  5E22 A;  3NCV A;  1D5G A;  2DM8 A;  1UEP A;  5B6L A;  2IWP A;  3ID3 A;  2PNT A;  2JIN A;  2KJK A;  4GVD A;  4PQW A;  5HF4 A;  2EAQ A;  3O46 A;  2CSS A;  2M0V A;  3SFJ A;  2H3L A;  5G1D A;  2EGO A;  5E1Y A;  1T2M A;  4JL7 A;  2VSP A;  1UEQ A;  3HVQ C;  1N6D A;  2KJD A;  1WIF A;  2GZV A;  1U37 A;  4K76 A;  1V6B A;  2LOB A;  3K50 A;  4Z8J A;  3PV5 A;  4NMT A;  2M0Z A;  1U38 A;  1UM1 A;  4HOP B;  2L4T A;  3QO6 A;  1MC7 A;  2MHO A;  1Y7N A;  1BE9 A;  1G9O A;  2OSG A;  2EJY A;  4H11 A;  2OS6 A;  2MX6 A;  1UFX A;  3DJA A;  1UHP A;  5D13 A;  2AWX A;  4G69 A;  1X5N A;  2Q9V A;  2KYL A;  2VZ5 A;  2I0L A;  1UJV A;  5IL9 A;  3HPM A;  1N7T A;  3OTP A;  2P3W A;  1FCF A;  1WF7 A;  3GDU A;  4E35 A;  1RGR A;  1WI2 A;  3KHF A;  2H3M A;  3GDV A;  4FGM A;  1U3B A;  2QKV A;  4UU5 A;  2JIK A;  2DKR A;  1VCW A;  3RLE A;  5GND A;  3VQF A;  1Z87 A;  5E11 A;  5HFB A;  2EEG A;  4NMO A;  1N99 A;  1X5Q A;  1R6J A;  4NMR A;  5HEY A;  2JWE A;  4NXQ A;  5GLJ A;  5HF1 A;  4JOK A;  1N6E A;  5HED A;  4O06 A;  1Z86 A;  5HFF A;  5HFD A;  2V90 A;  1B8Q A;  3KDK A;  1TQ3 A;  3R0H A;  3ZRT A;  3PV4 A;  1VA8 A;  4Q2N A;  5HFE A;  1RZX A;  2D90 A;  3GCO A;  4N6X A;  2IWO A;  3FY5 A;  3QDO A;  3SHW A;  5HDY A;  2DLU A;  2F5Y A;  1ZUB A;  1V1T A;  2QG1 A;  4Q2Q A;  4NMV A;  2OGP A;  1UJD A;  2IWQ A;  3MH7 A;  5F67 A;  2D8I A;  2DJT A;  1FC9 A;  3TMH A;  1GQ4 A;  3CS0 A;  2KPK A;  2UZC A;  3CBZ A;  3ID4 A;  3KZE A;  1NF3 C;  4Q2P A;  3WKM A;  3O5N A;  1UEW A;  2F0A A;  3KZD A;  3VQG A;  1WHA A;  3MH6 A;  3GSL A;  2AWU A;  4REY A;  1MFG A;  2FE5 A;  1V5Q A;  1TP5 A;  5E6P B;  3GJ9 A;  2YUB A;  2YUY A;  5A2P A;  1OBZ A;  2KOJ A;  1K32 A;  2HGA A;  1QAV B;  4JOJ A;  3I4W A;  2EEH A;  2LC6 A;  1YBO A;  1WF8 A;  1X5R A;  1UEZ A;  2DAZ A;  3AXA A;  3ID2 A;  1WFV A;  3LNX A;  4Q6H A;  5FHT A;  3EGG C;  1P1E A;  2HE2 A;  3DJ1 A;  2VRF A;  2LC7 A;  3DJ3 A;  4FLN A;  1N6F A;  2PZD A;  3CBY A;  4WYT A;  1V5L A;  1IU2 A;  1UM7 A;  2OMJ A;  2E7K A;  4JOF A;  3SOE A;  3R69 A;  2DMZ A;  5E21 A;  2W4F A;  1Q7X A;  3NGH A;  4Q6S A;  2VSV A;  4JJ3 A;  5FB8 C;  1IHJ A;  2FCF A;  2M3M A;  3TSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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