3M7PA

Fibronectin fragment
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
308
structure length
301
Chain Sequence
QPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Zinc Induces Structural Reorganization of Gelatin Binding Domain from Human Fibronectin and Affects Collagen Binding
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords FN1 protein
total genus 66
structure length 301
sequence length 308
ec nomenclature
pdb deposition date 2010-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00039 fn1 Fibronectin type I domain
A PF00040 fn2 Fibronectin type II domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3m7pA03
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3m7pA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3m7pA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3m7pA04
5I0QB 3GOVA 1KS0A 3ERBA 3KXVA 4LOSA 3EJHA 1E88A 2QY0A 2RKZA 3R62A 5HYPA 1OK2A 1MD7A 4KKDA 1CK7A 1PPQA 1OK3A 1J7MA 2MCZA 3SW0X 2IZ4A 1GKGA 3ZD1A 1FBRA 3CALA 1VVDA 1ELVA 1E5GA 4ONTD 2XWJI 1H03P 4B2SA 1G4GA 2XWBF 4LOTA 1O9AA 1QO6A 1H04P 1OJVA 1Q3XA 1HFHA 1ZJKA 4FXGG 5HYTB 3O8EB 1QGBA 1EAKA 2CG7A 1GXDA 2W81A 4JHSA 1CKLA 2XRBA 1HFIA 1E8BA 4CSYA 3L89M 3M7PA 4DJZA 4J38B 3ZRZA 2A55A 3OXUD 1OJYA 1H2PP 2XQWC 2EHFA 2IZ3A 3OP8A 4AYEA 1OK1A 1TPMA 5FO8C 1G4FA 2JRAA 1H8PA 2LOJA 5HYUB 5JPMG 4WJG2 4ZH1D 2RLPA 1UOTP 4IGDA 2KMSA 2RLQA 2RKYA 2O39C 1MD8A 1SS2A 2RL0A 2JGXA 2EC3A 1NWVA 2WIIC 2MCYA 1OK9A 3GXEA 3KZJA 4AYMA 2G7IA 2CG6A 3ZD2A 3IU3I 4C16A 1TPGA 2FN2A 2ERJA 4PZ5A 2YRAA 2BZMA 2V8EA 1HCCA 1GKNA 2W80A 3INBC 3TVJA 1C1ZA 4YNXA 3OEDC 1CXWA 4A5WB 1GPZA 1TPNA 3MQLA 2JGWA 1QUBA 1OJWA 2CKUA 4MUCA 3NFPI 2KRIA 5HZPB 1H2QP 3T5OA 2B5ID 1GHQB 3IX0A 3RJ3D 2V5OA 1SRZA 4B2RA 2UWNA 1Z92B 1VVCA 2XRDA 2YBYA 4K12A 4AYDA 4AYIA 1L6JA 1PDCA 1LY2A 4F4OC 1U5MA
chains in the Genus database with same CATH superfamily
5I0QB 3GOVA 4HMDA 1KS0A 4NZ1A 3ERBA 3KXVA 4LOSA 4MB5A 4Z2KA 3EJHA 2Y2GA 1GOIA 1E88A 2QY0A 2RKZA 3R62A 3KS4A 3FGTA 5HYPA 4NZ5A 1OK2A 4HMEA 1MD7A 4KKDA 2Y2HA 4OUIA 1CK7A 1PPQA 1OK3A 4Z2JA 1J7MA 3WX7A 2MCZA 4OJ5A 2XD5A 3SW0X 2UWXA 4QNLA 2IZ4A 1GKGA 3ZD1A 1FBRA 4OJLA 3CALA 4Z2HA 2BG1A 3WD1A 5BPVA 1VVDA 1ELVA 1E5GA 3WSXA 4ONTD 2XWJI 1H03P 4B2SA 4N7EA 4TX8A 3WD4A 1G4GA 2XWBF 4LOTA 4IBGA 1YU3A 1O9AA 1QO6A 2Y2IA 1H04P 1OJVA 1Q3XA 1AIWA 1HFHA 1ZJKA 4FXGG 2Y8TA 5HYTB 3O8EB 1QGBA 3F6KA 3K3TA 1EAKA 2CG7A 1GPFA 1GXDA 1W1YA 4IBCA 4GH9A 4MB4A 1ED7A 1CKLA 2I2LA 1UR8A 2W81A 4JHSA 2Y2KA 3FGRA 1E6ZA 3WD3A 2XRBA 1HFIA 1YU1A 1E8BA 3L29A 1W1TA 4CSYA 3L89M 3M7PA 4BWCA 5DN5A 4NYUA 4J38B 4IBEA 1W1PA 2Y2MA 4DJZA 4GHLA 3ZRZA 5DN4A 4MB3A 2A55A 2Y2PA 3L28A 3VWOA 3CI0J 1E6NA 3WD0A 1UR9A 3OXUD 1OJYA 2IOUA 2XD1A 4IJEA 1H2PP 2XQWC 4HMCA 4IBDA 2EHFA 1YUEA 2IZ3A 3OP8A 4AYEA 1YU0A 1OK1A 4MSLA 1TPMA 4NY2A 5FO8C 3L2AA 2JRAA 1G4FA 1H8PA 3N3FA 2LOJA 5HYUB 5JPMG 4WJG2 3WSYA 3L25A 2RLPA 1UOTP 4APLA 4ZH1D 3WD2A 4IGDA 2KMSA 2D49A 2RLQA 2X2ZA 2Y8SA 2Y2NA 2JE5A 4IBIA 4OJOA 2Y2OA 2RKYA 2JCHA 4Z2IA 2O39C 2FFFB 1H0IA 1MD8A 1SS2A 2RL0A 2JGXA 2EC3A 3FKEA 2RTSA 4IBJA 1H0GA 3HONA 1NWVA 1OK9A 2MCYA 2WIIC 3GXEA 3KZJA 3ZLDA 4AYMA 1W1VA 2G7IA 2Y2JA 2CG6A 3ZD2A 3L26A 3IU3I 4C16A 4Z2LA 2FN2A 1TPGA 2ERJA 4PZ5A 1RLHA 2YRAA 2BZMA 1O6IA 4Z2GA 1HCCA 2V8EA 2W80A 1GKNA 1YU2A 3INBC 3TVJA 1E6RA 1OGBA 2Y2QA 4NZ4A 1CXWA 1OGGA 1C1ZA 4IBFA 4LG2A 1GPZA 3NJAA 3OEDC 4A5WB 1TPNA 3MQLA 4YIZA 2JGWA 1QUBA 2Y8RA 3ZLEA 1OJWA 1YU4A 4IBBA 4IBKA 2CKUA 4MUCA 4PO7A 3NFPI 3L27A 4GHAA 2Y2LA 3HSHA 4NZ3A 2KRIA 5HZPB 1H2QP 4NYYA 3T5OA 2B5ID 1GHQB 3IX0A 3RJ3D 1E15A 2V5OA 4IJFA 1SRZA 2UWNA 1Z92B 1VVCA 4YNXA 2XRDA 4B2RA 2YBYA 4K12A 4OJPA 4OJ6A 4AYDA 1E6PA 4AYIA 1L6JA 2ZYCA 1PDCA 3KS8A 1LY2A 4F4OC 1U5MA
chains in the Genus database with same CATH topology
5I0QB 3GOVA 1KS0A 3ERBA 3KXVA 4LOSA 3EJHA 1E88A 2QY0A 2RKZA 3R62A 5HYPA 1OK2A 1MD7A 4KKDA 1CK7A 1PPQA 1OK3A 1J7MA 2MCZA 3SW0X 2IZ4A 1GKGA 3ZD1A 1FBRA 3CALA 1VVDA 1ELVA 1E5GA 4ONTD 2XWJI 1H03P 4B2SA 1G4GA 2XWBF 4LOTA 1O9AA 1QO6A 1H04P 1OJVA 1Q3XA 1HFHA 1ZJKA 4FXGG 5HYTB 3O8EB 1QGBA 1EAKA 2CG7A 1GXDA 2W81A 4JHSA 1CKLA 2XRBA 1HFIA 1E8BA 4CSYA 3L89M 3M7PA 4DJZA 4J38B 3ZRZA 2A55A 3OXUD 1OJYA 1H2PP 2XQWC 2EHFA 2IZ3A 3OP8A 4AYEA 1OK1A 1TPMA 5FO8C 1G4FA 2JRAA 1H8PA 2LOJA 5HYUB 5JPMG 4WJG2 4ZH1D 2RLPA 1UOTP 4IGDA 2KMSA 2RLQA 2RKYA 2O39C 1MD8A 1SS2A 2RL0A 2JGXA 2EC3A 1NWVA 2WIIC 2MCYA 1OK9A 3GXEA 3KZJA 4AYMA 2G7IA 2CG6A 3ZD2A 3IU3I 4C16A 1TPGA 2FN2A 2ERJA 4PZ5A 2YRAA 2BZMA 2V8EA 1HCCA 1GKNA 2W80A 3INBC 3TVJA 1C1ZA 4YNXA 3OEDC 1CXWA 4A5WB 1GPZA 1TPNA 3MQLA 2JGWA 1QUBA 1OJWA 2CKUA 4MUCA 3NFPI 2KRIA 5HZPB 1H2QP 3T5OA 2B5ID 1GHQB 3IX0A 3RJ3D 2V5OA 1SRZA 4B2RA 2UWNA 1Z92B 1VVCA 2XRDA 2YBYA 4K12A 4AYDA 4AYIA 1L6JA 1PDCA 1LY2A 4F4OC 1U5MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I0Q B;  3GOV A;  1KS0 A;  3ERB A;  3KXV A;  4LOS A;  3EJH A;  1E88 A;  2QY0 A;  2RKZ A;  3R62 A;  5HYP A;  1OK2 A;  1MD7 A;  4KKD A;  1CK7 A;  1PPQ A;  1OK3 A;  1J7M A;  2MCZ A;  3SW0 X;  2IZ4 A;  1GKG A;  3ZD1 A;  1FBR A;  3CAL A;  1VVD A;  1ELV A;  1E5G A;  4ONT D;  2XWJ I;  1H03 P;  4B2S A;  1G4G A;  2XWB F;  4LOT A;  1O9A A;  1QO6 A;  1H04 P;  1OJV A;  1Q3X A;  1HFH A;  1ZJK A;  4FXG G;  5HYT B;  3O8E B;  1QGB A;  1EAK A;  2CG7 A;  1GXD A;  2W81 A;  4JHS A;  1CKL A;  2XRB A;  1HFI A;  1E8B A;  4CSY A;  3L89 M;  3M7P A;  4DJZ A;  4J38 B;  3ZRZ A;  2A55 A;  3OXU D;  1OJY A;  1H2P P;  2XQW C;  2EHF A;  2IZ3 A;  3OP8 A;  4AYE A;  1OK1 A;  1TPM A;  5FO8 C;  1G4F A;  2JRA A;  1H8P A;  2LOJ A;  5HYU B;  5JPM G;  4WJG 2;  4ZH1 D;  2RLP A;  1UOT P;  4IGD A;  2KMS A;  2RLQ A;  2RKY A;  2O39 C;  1MD8 A;  1SS2 A;  2RL0 A;  2JGX A;  2EC3 A;  1NWV A;  2WII C;  2MCY A;  1OK9 A;  3GXE A;  3KZJ A;  4AYM A;  2G7I A;  2CG6 A;  3ZD2 A;  3IU3 I;  4C16 A;  1TPG A;  2FN2 A;  2ERJ A;  4PZ5 A;  2YRA A;  2BZM A;  2V8E A;  1HCC A;  1GKN A;  2W80 A;  3INB C;  3TVJ A;  1C1Z A;  4YNX A;  3OED C;  1CXW A;  4A5W B;  1GPZ A;  1TPN A;  3MQL A;  2JGW A;  1QUB A;  1OJW A;  2CKU A;  4MUC A;  3NFP I;  2KRI A;  5HZP B;  1H2Q P;  3T5O A;  2B5I D;  1GHQ B;  3IX0 A;  3RJ3 D;  2V5O A;  1SRZ A;  4B2R A;  2UWN A;  1Z92 B;  1VVC A;  2XRD A;  2YBY A;  4K12 A;  4AYD A;  4AYI A;  1L6J A;  1PDC A;  1LY2 A;  4F4O C;  1U5M A; 
#chains in the Genus database with same CATH topology
 5I0Q B;  3GOV A;  4HMD A;  1KS0 A;  4NZ1 A;  3ERB A;  3KXV A;  4LOS A;  4MB5 A;  4Z2K A;  3EJH A;  2Y2G A;  1GOI A;  1E88 A;  2QY0 A;  2RKZ A;  3R62 A;  3KS4 A;  3FGT A;  5HYP A;  4NZ5 A;  1OK2 A;  4HME A;  1MD7 A;  4KKD A;  2Y2H A;  4OUI A;  1CK7 A;  1PPQ A;  1OK3 A;  4Z2J A;  1J7M A;  3WX7 A;  2MCZ A;  4OJ5 A;  2XD5 A;  3SW0 X;  2UWX A;  4QNL A;  2IZ4 A;  1GKG A;  3ZD1 A;  1FBR A;  4OJL A;  3CAL A;  4Z2H A;  2BG1 A;  3WD1 A;  5BPV A;  1VVD A;  1ELV A;  1E5G A;  3WSX A;  4ONT D;  2XWJ I;  1H03 P;  4B2S A;  4N7E A;  4TX8 A;  3WD4 A;  1G4G A;  2XWB F;  4LOT A;  4IBG A;  1YU3 A;  1O9A A;  1QO6 A;  2Y2I A;  1H04 P;  1OJV A;  1Q3X A;  1AIW A;  1HFH A;  1ZJK A;  4FXG G;  2Y8T A;  5HYT B;  3O8E B;  1QGB A;  3F6K A;  3K3T A;  1EAK A;  2CG7 A;  1GPF A;  1GXD A;  1W1Y A;  4IBC A;  4GH9 A;  4MB4 A;  1ED7 A;  1CKL A;  2I2L A;  1UR8 A;  2W81 A;  4JHS A;  2Y2K A;  3FGR A;  1E6Z A;  3WD3 A;  2XRB A;  1HFI A;  1YU1 A;  1E8B A;  3L29 A;  1W1T A;  4CSY A;  3L89 M;  3M7P A;  4BWC A;  5DN5 A;  4NYU A;  4J38 B;  4IBE A;  1W1P A;  2Y2M A;  4DJZ A;  4GHL A;  3ZRZ A;  5DN4 A;  4MB3 A;  2A55 A;  2Y2P A;  3L28 A;  3VWO A;  3CI0 J;  1E6N A;  3WD0 A;  1UR9 A;  3OXU D;  1OJY A;  2IOU A;  2XD1 A;  4IJE A;  1H2P P;  2XQW C;  4HMC A;  4IBD A;  2EHF A;  1YUE A;  2IZ3 A;  3OP8 A;  4AYE A;  1YU0 A;  1OK1 A;  4MSL A;  1TPM A;  4NY2 A;  5FO8 C;  3L2A A;  2JRA A;  1G4F A;  1H8P A;  3N3F A;  2LOJ A;  5HYU B;  5JPM G;  4WJG 2;  3WSY A;  3L25 A;  2RLP A;  1UOT P;  4APL A;  4ZH1 D;  3WD2 A;  4IGD A;  2KMS A;  2D49 A;  2RLQ A;  2X2Z A;  2Y8S A;  2Y2N A;  2JE5 A;  4IBI A;  4OJO A;  2Y2O A;  2RKY A;  2JCH A;  4Z2I A;  2O39 C;  2FFF B;  1H0I A;  1MD8 A;  1SS2 A;  2RL0 A;  2JGX A;  2EC3 A;  3FKE A;  2RTS A;  4IBJ A;  1H0G A;  3HON A;  1NWV A;  1OK9 A;  2MCY A;  2WII C;  3GXE A;  3KZJ A;  3ZLD A;  4AYM A;  1W1V A;  2G7I A;  2Y2J A;  2CG6 A;  3ZD2 A;  3L26 A;  3IU3 I;  4C16 A;  4Z2L A;  2FN2 A;  1TPG A;  2ERJ A;  4PZ5 A;  1RLH A;  2YRA A;  2BZM A;  1O6I A;  4Z2G A;  1HCC A;  2V8E A;  2W80 A;  1GKN A;  1YU2 A;  3INB C;  3TVJ A;  1E6R A;  1OGB A;  2Y2Q A;  4NZ4 A;  1CXW A;  1OGG A;  1C1Z A;  4IBF A;  4LG2 A;  1GPZ A;  3NJA A;  3OED C;  4A5W B;  1TPN A;  3MQL A;  4YIZ A;  2JGW A;  1QUB A;  2Y8R A;  3ZLE A;  1OJW A;  1YU4 A;  4IBB A;  4IBK A;  2CKU A;  4MUC A;  4PO7 A;  3NFP I;  3L27 A;  4GHA A;  2Y2L A;  3HSH A;  4NZ3 A;  2KRI A;  5HZP B;  1H2Q P;  4NYY A;  3T5O A;  2B5I D;  1GHQ B;  3IX0 A;  3RJ3 D;  1E15 A;  2V5O A;  4IJF A;  1SRZ A;  2UWN A;  1Z92 B;  1VVC A;  4YNX A;  2XRD A;  4B2R A;  2YBY A;  4K12 A;  4OJP A;  4OJ6 A;  4AYD A;  1E6P A;  4AYI A;  1L6J A;  2ZYC A;  1PDC A;  3KS8 A;  1LY2 A;  4F4O C;  1U5M A; 
#chains in the Genus database with same CATH homology
 5I0Q B;  3GOV A;  1KS0 A;  3ERB A;  3KXV A;  4LOS A;  3EJH A;  1E88 A;  2QY0 A;  2RKZ A;  3R62 A;  5HYP A;  1OK2 A;  1MD7 A;  4KKD A;  1CK7 A;  1PPQ A;  1OK3 A;  1J7M A;  2MCZ A;  3SW0 X;  2IZ4 A;  1GKG A;  3ZD1 A;  1FBR A;  3CAL A;  1VVD A;  1ELV A;  1E5G A;  4ONT D;  2XWJ I;  1H03 P;  4B2S A;  1G4G A;  2XWB F;  4LOT A;  1O9A A;  1QO6 A;  1H04 P;  1OJV A;  1Q3X A;  1HFH A;  1ZJK A;  4FXG G;  5HYT B;  3O8E B;  1QGB A;  1EAK A;  2CG7 A;  1GXD A;  2W81 A;  4JHS A;  1CKL A;  2XRB A;  1HFI A;  1E8B A;  4CSY A;  3L89 M;  3M7P A;  4DJZ A;  4J38 B;  3ZRZ A;  2A55 A;  3OXU D;  1OJY A;  1H2P P;  2XQW C;  2EHF A;  2IZ3 A;  3OP8 A;  4AYE A;  1OK1 A;  1TPM A;  5FO8 C;  1G4F A;  2JRA A;  1H8P A;  2LOJ A;  5HYU B;  5JPM G;  4WJG 2;  4ZH1 D;  2RLP A;  1UOT P;  4IGD A;  2KMS A;  2RLQ A;  2RKY A;  2O39 C;  1MD8 A;  1SS2 A;  2RL0 A;  2JGX A;  2EC3 A;  1NWV A;  2WII C;  2MCY A;  1OK9 A;  3GXE A;  3KZJ A;  4AYM A;  2G7I A;  2CG6 A;  3ZD2 A;  3IU3 I;  4C16 A;  1TPG A;  2FN2 A;  2ERJ A;  4PZ5 A;  2YRA A;  2BZM A;  2V8E A;  1HCC A;  1GKN A;  2W80 A;  3INB C;  3TVJ A;  1C1Z A;  4YNX A;  3OED C;  1CXW A;  4A5W B;  1GPZ A;  1TPN A;  3MQL A;  2JGW A;  1QUB A;  1OJW A;  2CKU A;  4MUC A;  3NFP I;  2KRI A;  5HZP B;  1H2Q P;  3T5O A;  2B5I D;  1GHQ B;  3IX0 A;  3RJ3 D;  2V5O A;  1SRZ A;  4B2R A;  2UWN A;  1Z92 B;  1VVC A;  2XRD A;  2YBY A;  4K12 A;  4AYD A;  4AYI A;  1L6J A;  1PDC A;  1LY2 A;  4F4O C;  1U5M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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