3MQLA

Crystal structure of the fibronectin 6fni1-2fnii7fni fragment
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
209
structure length
209
Chain Sequence
YGDCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Fibronectin 1
total genus 38
structure length 209
sequence length 209
ec nomenclature
pdb deposition date 2010-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00039 fn1 Fibronectin type I domain
A PF00040 fn2 Fibronectin type II domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3mqlA03
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3mqlA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3mqlA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3mqlA04
1GPZA 3T5OA 5HZPB 4MUCA 2QY0A 4KKDA 3INBC 1ELVA 1CXWA 1O9AA 2XWBF 1H8PA 4LOTA 2YRAA 4CSYA 3ERBA 1GKNA 4C16A 5HYUB 1J7MA 1OK9A 1TPGA 4WJG2 4DJZA 1GXDA 2IZ4A 2A55A 1CKLA 1HFHA 1G4FA 3IU3I 3ZD2A 2WIIC 3MQLA 2RKYA 4AYEA 1H04P 4ONTD 1PPQA 1E88A 3IX0A 3KZJA 2KRIA 3KXVA 2B5ID 1TPMA 5FO8C 1H03P 2MCYA 3OXUD 4YNXA 1GKGA 1UOTP 2RLPA 2EC3A 1Z92B 2MCZA 2V5OA 2LOJA 3RJ3D 5HYPA 2BZMA 4K12A 3R62A 2O39C 1OJWA 2RKZA 3ZRZA 5I0QB 4IGDA 4LOSA 1CK7A 1HCCA 4B2RA 2JRAA 1KS0A 1E5GA 1LY2A 4J38B 1OJYA 1U5MA 2RLQA 4F4OC 4PZ5A 4FXGG 2W80A 2EHFA 5HYTB 2XQWC 1FBRA 1VVCA 2CG7A 1HFIA 3EJHA 4A5WB 1SS2A 2ERJA 4AYIA 1H2QP 3GXEA 1QGBA 1PDCA 2RL0A 1H2PP 3NFPI 2XWJI 3CALA 1MD7A 3SW0X 1QO6A 3OEDC 1C1ZA 1GHQB 1E8BA 1OJVA 1NWVA 3O8EB 3OP8A 1SRZA 3ZD1A 4B2SA 1TPNA 5JPMG 2W81A 2CG6A 1OK2A 1QUBA 1MD8A 1G4GA 1Q3XA 3L89M 3GOVA 4JHSA 1VVDA 1L6JA 2G7IA 2XRDA 2YBYA 3TVJA 2V8EA 2UWNA 3M7PA 2JGXA 2XRBA 4ZH1D 2CKUA 2FN2A 4AYDA 1EAKA 2KMSA 1ZJKA 4AYMA 1OK3A 2IZ3A 1OK1A 2JGWA
chains in the Genus database with same CATH superfamily
3NFPI 1GPZA 3T5OA 5HZPB 2ZYCA 1YU3A 4GH9A 1O6IA 5DN4A 4MUCA 2QY0A 4PO7A 4BWCA 4KKDA 4GHAA 2Y2NA 4NZ1A 3INBC 1ELVA 3WSXA 4IJFA 3WD0A 4IBIA 1CXWA 1O9AA 2XWBF 1H8PA 3L26A 3FGTA 2YRAA 4LOTA 4CSYA 3ERBA 1GKNA 1YUEA 3L2AA 4IBJA 4C16A 5HYUB 1W1VA 4Z2HA 1J7MA 1OK9A 1TPGA 4LG2A 4WJG2 4DJZA 1GXDA 4HMDA 1YU4A 3L25A 2IZ4A 2A55A 1CKLA 3KS4A 4NYUA 2UWXA 1HFHA 1G4FA 3IU3I 3HONA 3ZD2A 3HSHA 2WIIC 3MQLA 1YU0A 2Y2OA 3L28A 4QNLA 1GOIA 2RKYA 4AYEA 1H04P 4ONTD 1PPQA 1E88A 3IX0A 3KZJA 2KRIA 1UR8A 3KXVA 1OGBA 2B5ID 1TPMA 5FO8C 4GHLA 1W1PA 2JE5A 1H03P 2MCYA 3OXUD 4NYYA 2Y8SA 4YNXA 2Y2JA 1GKGA 3L29A 4Z2JA 4APLA 5DN5A 1UOTP 2RLPA 2EC3A 1E6PA 1Z92B 2MCZA 2V5OA 2LOJA 3RJ3D 5HYPA 2BZMA 4K12A 4Z2LA 1ED7A 3R62A 4MB4A 4IBDA 2O39C 1OJWA 4N7EA 2RKZA 1YU1A 3ZRZA 2XD5A 3FGRA 2BG1A 4NY2A 5I0QB 1AIWA 4MB3A 3WD2A 4IGDA 4LOSA 1CK7A 1HCCA 4B2RA 2JCHA 2JRAA 4OJ5A 1KS0A 1E5GA 2X2ZA 1W1YA 4MB5A 1LY2A 4NZ5A 4J38B 1OJYA 1U5MA 2RLQA 4F4OC 2FFFB 4PZ5A 2Y2PA 4FXGG 3ZLDA 2W80A 2EHFA 1UR9A 2XQWC 1FBRA 5HYTB 1VVCA 2CG7A 1HFIA 3WD3A 3EJHA 4A5WB 1SS2A 2ERJA 2I2LA 1E6RA 3N3FA 3L27A 4AYIA 4OJLA 2Y2IA 2Y2QA 3KS8A 1H2QP 1E15A 3GXEA 1QGBA 1PDCA 2RL0A 4Z2KA 1H2PP 2XWJI 4IBKA 1MD7A 2XD1A 1QO6A 3FKEA 4IBEA 3CALA 3SW0X 4IJEA 3OEDC 1C1ZA 4NZ4A 1GHQB 4OUIA 3NJAA 1E8BA 4IBFA 1OJVA 1RLHA 1NWVA 3O8EB 3OP8A 1SRZA 3WSYA 1W1TA 3ZD1A 4B2SA 1TPNA 3VWOA 2IOUA 5JPMG 2W81A 2CG6A 4Z2GA 2Y8TA 1OK2A 1E6ZA 2Y2KA 4NZ3A 4IBBA 1QUBA 2Y8RA 1MD8A 3WD1A 1G4GA 1Q3XA 5BPVA 1E6NA 3WD4A 3CI0J 4HMEA 3L89M 1GPFA 3GOVA 4JHSA 1H0GA 1L6JA 1VVDA 3K3TA 4IBGA 2G7IA 2XRDA 2YBYA 1OGGA 3TVJA 2V8EA 2UWNA 2RTSA 3M7PA 2JGXA 2XRBA 3F6KA 4TX8A 3WX7A 4ZH1D 2Y2LA 2CKUA 2FN2A 2D49A 4AYDA 1EAKA 1YU2A 4YIZA 2KMSA 4Z2IA 4MSLA 2JGWA 1ZJKA 1H0IA 3ZLEA 2Y2HA 4HMCA 4IBCA 4OJPA 4AYMA 1OK3A 2Y2GA 2Y2MA 2IZ3A 4OJOA 1OK1A 4OJ6A
chains in the Genus database with same CATH topology
1GPZA 3T5OA 5HZPB 4MUCA 2QY0A 4KKDA 3INBC 1ELVA 1CXWA 1O9AA 2XWBF 1H8PA 4LOTA 2YRAA 4CSYA 3ERBA 1GKNA 4C16A 5HYUB 1J7MA 1OK9A 1TPGA 4WJG2 4DJZA 1GXDA 2IZ4A 2A55A 1CKLA 1HFHA 1G4FA 3IU3I 3ZD2A 2WIIC 3MQLA 2RKYA 4AYEA 1H04P 4ONTD 1PPQA 1E88A 3IX0A 3KZJA 2KRIA 3KXVA 2B5ID 1TPMA 5FO8C 1H03P 2MCYA 3OXUD 4YNXA 1GKGA 1UOTP 2RLPA 2EC3A 1Z92B 2MCZA 2V5OA 2LOJA 3RJ3D 5HYPA 2BZMA 4K12A 3R62A 2O39C 1OJWA 2RKZA 3ZRZA 5I0QB 4IGDA 4LOSA 1CK7A 1HCCA 4B2RA 2JRAA 1KS0A 1E5GA 1LY2A 4J38B 1OJYA 1U5MA 2RLQA 4F4OC 4PZ5A 4FXGG 2W80A 2EHFA 5HYTB 2XQWC 1FBRA 1VVCA 2CG7A 1HFIA 3EJHA 4A5WB 1SS2A 2ERJA 4AYIA 1H2QP 3GXEA 1QGBA 1PDCA 2RL0A 1H2PP 3NFPI 2XWJI 3CALA 1MD7A 3SW0X 1QO6A 3OEDC 1C1ZA 1GHQB 1E8BA 1OJVA 1NWVA 3O8EB 3OP8A 1SRZA 3ZD1A 4B2SA 1TPNA 5JPMG 2W81A 2CG6A 1OK2A 1QUBA 1MD8A 1G4GA 1Q3XA 3L89M 3GOVA 4JHSA 1VVDA 1L6JA 2G7IA 2XRDA 2YBYA 3TVJA 2V8EA 2UWNA 3M7PA 2JGXA 2XRBA 4ZH1D 2CKUA 2FN2A 4AYDA 1EAKA 2KMSA 1ZJKA 4AYMA 1OK3A 2IZ3A 1OK1A 2JGWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GPZ A;  3T5O A;  5HZP B;  4MUC A;  2QY0 A;  4KKD A;  3INB C;  1ELV A;  1CXW A;  1O9A A;  2XWB F;  1H8P A;  4LOT A;  2YRA A;  4CSY A;  3ERB A;  1GKN A;  4C16 A;  5HYU B;  1J7M A;  1OK9 A;  1TPG A;  4WJG 2;  4DJZ A;  1GXD A;  2IZ4 A;  2A55 A;  1CKL A;  1HFH A;  1G4F A;  3IU3 I;  3ZD2 A;  2WII C;  3MQL A;  2RKY A;  4AYE A;  1H04 P;  4ONT D;  1PPQ A;  1E88 A;  3IX0 A;  3KZJ A;  2KRI A;  3KXV A;  2B5I D;  1TPM A;  5FO8 C;  1H03 P;  2MCY A;  3OXU D;  4YNX A;  1GKG A;  1UOT P;  2RLP A;  2EC3 A;  1Z92 B;  2MCZ A;  2V5O A;  2LOJ A;  3RJ3 D;  5HYP A;  2BZM A;  4K12 A;  3R62 A;  2O39 C;  1OJW A;  2RKZ A;  3ZRZ A;  5I0Q B;  4IGD A;  4LOS A;  1CK7 A;  1HCC A;  4B2R A;  2JRA A;  1KS0 A;  1E5G A;  1LY2 A;  4J38 B;  1OJY A;  1U5M A;  2RLQ A;  4F4O C;  4PZ5 A;  4FXG G;  2W80 A;  2EHF A;  5HYT B;  2XQW C;  1FBR A;  1VVC A;  2CG7 A;  1HFI A;  3EJH A;  4A5W B;  1SS2 A;  2ERJ A;  4AYI A;  1H2Q P;  3GXE A;  1QGB A;  1PDC A;  2RL0 A;  1H2P P;  3NFP I;  2XWJ I;  3CAL A;  1MD7 A;  3SW0 X;  1QO6 A;  3OED C;  1C1Z A;  1GHQ B;  1E8B A;  1OJV A;  1NWV A;  3O8E B;  3OP8 A;  1SRZ A;  3ZD1 A;  4B2S A;  1TPN A;  5JPM G;  2W81 A;  2CG6 A;  1OK2 A;  1QUB A;  1MD8 A;  1G4G A;  1Q3X A;  3L89 M;  3GOV A;  4JHS A;  1VVD A;  1L6J A;  2G7I A;  2XRD A;  2YBY A;  3TVJ A;  2V8E A;  2UWN A;  3M7P A;  2JGX A;  2XRB A;  4ZH1 D;  2CKU A;  2FN2 A;  4AYD A;  1EAK A;  2KMS A;  1ZJK A;  4AYM A;  1OK3 A;  2IZ3 A;  1OK1 A;  2JGW A; 
#chains in the Genus database with same CATH topology
 3NFP I;  1GPZ A;  3T5O A;  5HZP B;  2ZYC A;  1YU3 A;  4GH9 A;  1O6I A;  5DN4 A;  4MUC A;  2QY0 A;  4PO7 A;  4BWC A;  4KKD A;  4GHA A;  2Y2N A;  4NZ1 A;  3INB C;  1ELV A;  3WSX A;  4IJF A;  3WD0 A;  4IBI A;  1CXW A;  1O9A A;  2XWB F;  1H8P A;  3L26 A;  3FGT A;  2YRA A;  4LOT A;  4CSY A;  3ERB A;  1GKN A;  1YUE A;  3L2A A;  4IBJ A;  4C16 A;  5HYU B;  1W1V A;  4Z2H A;  1J7M A;  1OK9 A;  1TPG A;  4LG2 A;  4WJG 2;  4DJZ A;  1GXD A;  4HMD A;  1YU4 A;  3L25 A;  2IZ4 A;  2A55 A;  1CKL A;  3KS4 A;  4NYU A;  2UWX A;  1HFH A;  1G4F A;  3IU3 I;  3HON A;  3ZD2 A;  3HSH A;  2WII C;  3MQL A;  1YU0 A;  2Y2O A;  3L28 A;  4QNL A;  1GOI A;  2RKY A;  4AYE A;  1H04 P;  4ONT D;  1PPQ A;  1E88 A;  3IX0 A;  3KZJ A;  2KRI A;  1UR8 A;  3KXV A;  1OGB A;  2B5I D;  1TPM A;  5FO8 C;  4GHL A;  1W1P A;  2JE5 A;  1H03 P;  2MCY A;  3OXU D;  4NYY A;  2Y8S A;  4YNX A;  2Y2J A;  1GKG A;  3L29 A;  4Z2J A;  4APL A;  5DN5 A;  1UOT P;  2RLP A;  2EC3 A;  1E6P A;  1Z92 B;  2MCZ A;  2V5O A;  2LOJ A;  3RJ3 D;  5HYP A;  2BZM A;  4K12 A;  4Z2L A;  1ED7 A;  3R62 A;  4MB4 A;  4IBD A;  2O39 C;  1OJW A;  4N7E A;  2RKZ A;  1YU1 A;  3ZRZ A;  2XD5 A;  3FGR A;  2BG1 A;  4NY2 A;  5I0Q B;  1AIW A;  4MB3 A;  3WD2 A;  4IGD A;  4LOS A;  1CK7 A;  1HCC A;  4B2R A;  2JCH A;  2JRA A;  4OJ5 A;  1KS0 A;  1E5G A;  2X2Z A;  1W1Y A;  4MB5 A;  1LY2 A;  4NZ5 A;  4J38 B;  1OJY A;  1U5M A;  2RLQ A;  4F4O C;  2FFF B;  4PZ5 A;  2Y2P A;  4FXG G;  3ZLD A;  2W80 A;  2EHF A;  1UR9 A;  2XQW C;  1FBR A;  5HYT B;  1VVC A;  2CG7 A;  1HFI A;  3WD3 A;  3EJH A;  4A5W B;  1SS2 A;  2ERJ A;  2I2L A;  1E6R A;  3N3F A;  3L27 A;  4AYI A;  4OJL A;  2Y2I A;  2Y2Q A;  3KS8 A;  1H2Q P;  1E15 A;  3GXE A;  1QGB A;  1PDC A;  2RL0 A;  4Z2K A;  1H2P P;  2XWJ I;  4IBK A;  1MD7 A;  2XD1 A;  1QO6 A;  3FKE A;  4IBE A;  3CAL A;  3SW0 X;  4IJE A;  3OED C;  1C1Z A;  4NZ4 A;  1GHQ B;  4OUI A;  3NJA A;  1E8B A;  4IBF A;  1OJV A;  1RLH A;  1NWV A;  3O8E B;  3OP8 A;  1SRZ A;  3WSY A;  1W1T A;  3ZD1 A;  4B2S A;  1TPN A;  3VWO A;  2IOU A;  5JPM G;  2W81 A;  2CG6 A;  4Z2G A;  2Y8T A;  1OK2 A;  1E6Z A;  2Y2K A;  4NZ3 A;  4IBB A;  1QUB A;  2Y8R A;  1MD8 A;  3WD1 A;  1G4G A;  1Q3X A;  5BPV A;  1E6N A;  3WD4 A;  3CI0 J;  4HME A;  3L89 M;  1GPF A;  3GOV A;  4JHS A;  1H0G A;  1L6J A;  1VVD A;  3K3T A;  4IBG A;  2G7I A;  2XRD A;  2YBY A;  1OGG A;  3TVJ A;  2V8E A;  2UWN A;  2RTS A;  3M7P A;  2JGX A;  2XRB A;  3F6K A;  4TX8 A;  3WX7 A;  4ZH1 D;  2Y2L A;  2CKU A;  2FN2 A;  2D49 A;  4AYD A;  1EAK A;  1YU2 A;  4YIZ A;  2KMS A;  4Z2I A;  4MSL A;  2JGW A;  1ZJK A;  1H0I A;  3ZLE A;  2Y2H A;  4HMC A;  4IBC A;  4OJP A;  4AYM A;  1OK3 A;  2Y2G A;  2Y2M A;  2IZ3 A;  4OJO A;  1OK1 A;  4OJ6 A; 
#chains in the Genus database with same CATH homology
 1GPZ A;  3T5O A;  5HZP B;  4MUC A;  2QY0 A;  4KKD A;  3INB C;  1ELV A;  1CXW A;  1O9A A;  2XWB F;  1H8P A;  4LOT A;  2YRA A;  4CSY A;  3ERB A;  1GKN A;  4C16 A;  5HYU B;  1J7M A;  1OK9 A;  1TPG A;  4WJG 2;  4DJZ A;  1GXD A;  2IZ4 A;  2A55 A;  1CKL A;  1HFH A;  1G4F A;  3IU3 I;  3ZD2 A;  2WII C;  3MQL A;  2RKY A;  4AYE A;  1H04 P;  4ONT D;  1PPQ A;  1E88 A;  3IX0 A;  3KZJ A;  2KRI A;  3KXV A;  2B5I D;  1TPM A;  5FO8 C;  1H03 P;  2MCY A;  3OXU D;  4YNX A;  1GKG A;  1UOT P;  2RLP A;  2EC3 A;  1Z92 B;  2MCZ A;  2V5O A;  2LOJ A;  3RJ3 D;  5HYP A;  2BZM A;  4K12 A;  3R62 A;  2O39 C;  1OJW A;  2RKZ A;  3ZRZ A;  5I0Q B;  4IGD A;  4LOS A;  1CK7 A;  1HCC A;  4B2R A;  2JRA A;  1KS0 A;  1E5G A;  1LY2 A;  4J38 B;  1OJY A;  1U5M A;  2RLQ A;  4F4O C;  4PZ5 A;  4FXG G;  2W80 A;  2EHF A;  5HYT B;  2XQW C;  1FBR A;  1VVC A;  2CG7 A;  1HFI A;  3EJH A;  4A5W B;  1SS2 A;  2ERJ A;  4AYI A;  1H2Q P;  3GXE A;  1QGB A;  1PDC A;  2RL0 A;  1H2P P;  3NFP I;  2XWJ I;  3CAL A;  1MD7 A;  3SW0 X;  1QO6 A;  3OED C;  1C1Z A;  1GHQ B;  1E8B A;  1OJV A;  1NWV A;  3O8E B;  3OP8 A;  1SRZ A;  3ZD1 A;  4B2S A;  1TPN A;  5JPM G;  2W81 A;  2CG6 A;  1OK2 A;  1QUB A;  1MD8 A;  1G4G A;  1Q3X A;  3L89 M;  3GOV A;  4JHS A;  1VVD A;  1L6J A;  2G7I A;  2XRD A;  2YBY A;  3TVJ A;  2V8E A;  2UWN A;  3M7P A;  2JGX A;  2XRB A;  4ZH1 D;  2CKU A;  2FN2 A;  4AYD A;  1EAK A;  2KMS A;  1ZJK A;  4AYM A;  1OK3 A;  2IZ3 A;  1OK1 A;  2JGW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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