3QJMA

Structural flexibility of shank pdz domain is important for its binding to different ligands
Total Genus 16
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
103
structure length
98
Chain Sequence
DYIIKEKTVLLQKKDSEGFGFVLRGAIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structural flexibility of the shank1 PDZ domain is important for its binding to different ligands
pubmed doi rcsb
molecule tags Protein binding
source organism Rattus norvegicus
molecule keywords SH3 and multiple ankyrin repeat domains protein 1
total genus 16
structure length 98
sequence length 103
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17820 PDZ_6 PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 3qjmA00
2LUIA 2YT7A 1YBOA 2HE4A 2D92A 4JOGA 5G1DA 2JIKA 2YT8A 1U37A 2UZCA 3ID3A 5E11A 2Z9IA 2F0AA 2EEGA 1B8QA 3SHUA 2JXOA 3VQFA 2KBSA 3MH4A 2QKTA 2MHOA 4R2ZA 2AWUA 1QAVB 4NMRA 1W9EA 4Q2OA 1M5ZA 3FY5A 1Y8TA 2MX6A 2ZPMA 1N99A 1G9OA 3CBYA 4HOPA 5HJ1A 1X6DA 2LA8A 3SUZA 1WI2A 5B6LA 4N6XA 2DKRA 2M0UA 2H2CA 2KQFA 1WI4A 5G1EA 3ID2A 4MPAA 3ZRTA 3R68A 2FN5A 1WF8A 2EGOA 2EEHA 4L8NA 5E6PB 3TSZA 2AWWA 3GDVA 2G5MB 4NMVA 2VPHA 2VSPA 2M0ZA 2EGNA 3NFLA 2DMZA 3GDSA 4Q3HA 2QKVA 1Z87A 4Q6SA 4NMTA 1KY9A 1RZXA 1IU2A 1TE0A 1BE9A 2EEIA 2KA9A 2WL7A 5HEDA 3CBZA 2OMJA 3KZDA 4NMPA 1UEPA 4K75A 2EJYA 5A2PA 1UJVA 3NFKA 1W9QA 2KOMA 3SOEA 3PDVA 1N6DA 2DC2A 1RY4A 4KFVA 3STJA 3RL7A 3R0HA 2JINA 2L4TA 4Q6HA 2M0VA 3CC0A 1UHPA 4JOJA 5HEBA 2JILA 4NMSA 4K78A 5E1YA 2V1WA 3NGHA 2AINA 3LNXA 1WFGA 2L4SA 1W9OA 5HF4A 2M10A 1WHDA 2CS5A 3QDOA 2BYGA 2Q3GA 2PA1A 2VRFA 1N7TA 3CBXA 2IWNA 5GNDA 1FC9A 1IU0A 5EZ0A 3AXAA 2DLUA 3TSVA 3EGGC 1UJUA 5HEYA 1GQ4A 3RL8A 2H3MA 4XHVA 3KZEA 2RCZA 1VB7A 2R4HA 1QAVA 3GGEA 2PKTA 3PDZA 1WFVA 2REYA 4Q2QA 1X8SA 3OTPA 2Z17A 1WJLA 1I92A 5E21A 1MC7A 4Z8JA 1OBYA 3GDUA 1U39A 3CH8A 4NMQA 2EXGA 1V5LA 1WIFA 2P3WA 1NTEA 3WKLA 4JOPA 2I0IA 3QIKA 4REYA 2FCFA 3QJMA 4FGMA 2L97A 4KFWA 4GVCA 2IWQA 4IC6A 1LCYA 4P0CA 4GHNA 2VSVA 3E17A 3CS0A 2QT5A 1RGWA 1QAUA 2I04A 3QGLA 2QBWA 2G2LA 3BPUA 1UM1A 1TQ3A 3PS4A 2DLSA 5I7ZA 1I16A 3GJ9A 3RLEA 5H3JA 4E3BA 2OZFA 3CYYA 2KRGA 1WH1A 3DJ3A 4NXQA 1KEFA 2K20A 5D13A 2HGAA 4RI0A 1Q3PA 1N7EA 4Q2PA 2OSGA 3K1RA 2LC7A 2QG1A 3I1EA 4NMOA 4WYTA 3DORA 2HE2A 3TMHA 1UM7A 2PNTA 2EV8A 5HFFA 2OPGA 1UJDA 4K76A 2GZVA 2RRMA 4WYUA 2DB5A 3R69A 2QKUA 1SOZA 1Y7NA 2FE5A 2PDZA 3QJNA 4JOHA 2CSSA 4JORA 1GM1A 1FCFA 2I1NA 3HVQC 1UFXA 2O2TA 1D5GA 2JWEA 5HFBA 4LMMA 4Q2NA 4PQWA 1V5QA 4OEOA 2W7RA 1MFLA 2ZPLA 4NXPA 3MH7A 5HETA 2KL1A 1Q7XA 1V62A 1X5NA 1X45A 4JOFA 1KWAA 4F8KA 2DJTA 2FNEA 2OS6A 2KV8A 3GSLA 2EEJA 2IWPA 3O46A 1T2MA 3TSWA 1VJ6A 2W4FA 5HFDA 1WG6A 2V90A 4Z33A 2M0TA 5HFEA 1UEQA 1SOTA 5HFCA 1FC7A 2KJPA 1Z86A 2VWRA 4NNMA 3HPMA 4G69A 1P1DA 2VZ5A 4E34A 4YDPA 5F3XA 3SFJA 3PV5A 1V1TA 1MFGA 1Q3OA 2I0LA 1UEZA 2D8IA 2KOHA 4O06A 1ZOKA 1U3BA 2EHRA 2Q9VA 2F5YA 4JOEA 3KHFA 1RGRA 1U38A 2EGKA 3HPKA 1X5QA 4YYXA 2X7ZA 5JXBA 4HOPB 3EGHC 3K50A 2DAZA 1V6BA 3PV2A 1N7FA 5FHTA 1FC6A 5FB8C 1TP5A 3SHWA 2PZDA 1UITA 4EDJA 4UU6A 2KPLA 2OQSA 3DJAA 3L4FD 2R3YA 2DM8A 3DJ1A 3ID1A 1L6OA 3VQGA 2KG2A 2LC6A 2EDPA 4H11A 1QLCA 1VAEA 4AMHA 1N6FA 2EAQA 1PDRA 3PV4A 3I18A 4OAJA 3B76A 2EDZA 4K72A 5DTHA 5GLJA 3WKMA 3GCOA 3GCNA 4K6YA 2D90A 1OBXA 2AWXA 2H3LA 2PKUA 1UF1A 1NF3C 2LOBA 2YUBA 1XZ9A 3LNYA 1R6JA 3ID4A 2KOJA 1ZUBA 2JOAA 3DIWA 1N6EA 2K1ZA 1OZIA 3QE1A 2M3MA 1OBZA 1TP3A 4UU5A 1WHAA 1VCWA 5EYZA 2KJKA 1VA8A 2I6VA 4GVDA 2YUYA 3MH6A 1P1EA 4OEPA 5F67A 2KPKA 2KJDA 2EDVA 3O5NA 3OU0A 2YTWA 1UEWA 4NNLA 1BFEA 1WF7A 4JL7A 3K82A 2H2BA 1GQ5A 3I4WA 2IWOA 2KYLA 1K32A 2JREA 2CSJA 2ENOA 4E35A 2I4SA 2OCSA 3JXTA 5HDYA 1X5RA 1IHJA 4NXRA 5E22A 2OGPA 4JOKA 4P2AB 3QO6A 2E7KA 2KAWA 5HF1A
chains in the Genus database with same CATH superfamily
2LUIA 2YT7A 1YBOA 2HE4A 2D92A 4JOGA 5G1DA 2JIKA 2YT8A 1U37A 2UZCA 3ID3A 5E11A 2Z9IA 2F0AA 2EEGA 1B8QA 3SHUA 2JXOA 3VQFA 5ILBA 2KBSA 3MH4A 2QKTA 2MHOA 4R2ZA 2AWUA 1QAVB 4NMRA 1W9EA 4Q2OA 1M5ZA 3FY5A 1Y8TA 2MX6A 2ZPMA 1N99A 1G9OA 3CBYA 4HOPA 5HJ1A 1X6DA 2LA8A 3SUZA 1WI2A 5B6LA 4N6XA 2DKRA 2M0UA 2H2CA 2KQFA 1WI4A 5G1EA 3ID2A 4MPAA 3ZRTA 3R68A 2FN5A 1WF8A 2EGOA 2EEHA 4L8NA 3KDGA 5E6PB 3TSZA 2AWWA 3GDVA 2G5MB 4NMVA 2VPHA 2VSPA 2M0ZA 2EGNA 3NFLA 2DMZA 3GDSA 4Q3HA 2QKVA 1Z87A 4Q6SA 4NMTA 1KY9A 1RZXA 1IU2A 1TE0A 1BE9A 2EEIA 2KA9A 2WL7A 5HEDA 3CBZA 2OMJA 3KZDA 4NMPA 1UEPA 4K75A 2EJYA 5A2PA 1UJVA 3NFKA 1W9QA 2KOMA 3SOEA 3KDKA 3PDVA 1N6DA 2DC2A 1RY4A 4KFVA 3STJA 3RL7A 3R0HA 2JINA 2JSNA 2L4TA 4Q6HA 2M0VA 3CC0A 1UHPA 4JOJA 5HEBA 2JILA 4NMSA 4K78A 5E1YA 2V1WA 3NGHA 2AINA 3LNXA 1WFGA 2L4SA 1W9OA 5HF4A 2M10A 1WHDA 2CS5A 3QDOA 2BYGA 2Q3GA 2PA1A 2VRFA 1N7TA 5B42A 3CBXA 2IWNA 5GNDA 1FC9A 1IU0A 5EZ0A 3AXAA 4JJ0A 2DLUA 3TSVA 3EGGC 1UJUA 5HEYA 1GQ4A 3RL8A 2H3MA 4XHVA 3KZEA 2RCZA 1VB7A 2R4HA 1QAVA 3GGEA 2PKTA 3PDZA 1WFVA 2REYA 4Q2QA 1X8SA 3OTPA 3NCVA 2Z17A 1WJLA 1I92A 5E21A 1MC7A 4Z8JA 1OBYA 5IL9A 3GDUA 1U39A 3CH8A 4NMQA 2EXGA 1V5LA 1WIFA 2P3WA 1NTEA 3WKLA 4JOPA 2I0IA 3QIKA 4REYA 2FCFA 3QJMA 4FGMA 2L97A 4KFWA 4GVCA 2IWQA 4IC6A 1LCYA 4P0CA 4GHNA 2VSVA 3E17A 3CS0A 2QT5A 1RGWA 1QAUA 2I04A 3QGLA 2QBWA 2G2LA 3BPUA 1UM1A 1TQ3A 3PS4A 2DLSA 5I7ZA 1I16A 3GJ9A 3RLEA 5H3JA 4E3BA 2OZFA 3CYYA 2KRGA 1WH1A 3DJ3A 4NXQA 1KEFA 2K20A 5D13A 2HGAA 3GABA 4RI0A 1Q3PA 1N7EA 4Q2PA 2OSGA 3K1RA 2LC7A 2QG1A 3I1EA 4NMOA 4WYTA 3DORA 2HE2A 3TMHA 1UM7A 2PNTA 2EV8A 5HFFA 2OPGA 1UJDA 4K76A 2GZVA 2RRMA 4WYUA 2DB5A 3R69A 2QKUA 1SOZA 1Y7NA 2FE5A 2PDZA 3QJNA 4JOHA 2CSSA 4JORA 1GM1A 1FCFA 2I1NA 3HVQC 1UFXA 2O2TA 1D5GA 2JWEA 5HFBA 4LMMA 4Q2NA 4PQWA 1V5QA 4OEOA 2W7RA 1MFLA 2ZPLA 4NXPA 3MH7A 5HETA 2KL1A 1Q7XA 1V62A 1X5NA 1X9ZA 1X45A 4JOFA 1KWAA 4F8KA 2DJTA 2FNEA 2OS6A 2KV8A 3GSLA 2EEJA 2IWPA 3O46A 1T2MA 3TSWA 1VJ6A 2W4FA 5HFDA 1WG6A 2V90A 4Z33A 2M0TA 5HFEA 1UEQA 1SOTA 5HFCA 1FC7A 2KJPA 1Z86A 2VWRA 4NNMA 3HPMA 4G69A 1P1DA 2VZ5A 4E34A 4YDPA 5F3XA 3SFJA 3PV5A 1V1TA 1MFGA 1Q3OA 2I0LA 1UEZA 2D8IA 2KOHA 4O06A 1ZOKA 1U3BA 2EHRA 2Q9VA 2F5YA 4JOEA 3KHFA 1RGRA 1U38A 2EGKA 3HPKA 1X5QA 4YYXA 2X7ZA 5JXBA 4HOPB 3EGHC 3K50A 2DAZA 1V6BA 3PV2A 1N7FA 5FHTA 1FC6A 4FLNA 5FB8C 1TP5A 3SHWA 2PZDA 1UITA 4EDJA 4UU6A 2KPLA 2OQSA 3DJAA 3L4FD 2R3YA 2DM8A 3DJ1A 3ID1A 1L6OA 3VQGA 2KG2A 2LC6A 2EDPA 4H11A 1QLCA 1VAEA 4AMHA 1N6FA 2EAQA 1PDRA 3PV4A 3I18A 4OAJA 3B76A 2EDZA 4K72A 5DTHA 5GLJA 3WKMA 3GCOA 3GCNA 4K6YA 2D90A 1OBXA 2AWXA 2H3LA 2PKUA 1UF1A 1NF3C 2LOBA 2YUBA 1XZ9A 3LNYA 1R6JA 4JJ3A 3ID4A 2KOJA 1ZUBA 2JOAA 3DIWA 1N6EA 2K1ZA 1OZIA 3QE1A 2M3MA 1OBZA 1TP3A 4UU5A 1WHAA 1VCWA 5EYZA 2KJKA 1VA8A 2I6VA 4GVDA 2YUYA 3MH6A 1P1EA 4OEPA 5F67A 2KPKA 2KJDA 2EDVA 3O5NA 3OU0A 2YTWA 1UEWA 4NNLA 1BFEA 1WF7A 2GEFA 4JL7A 3K82A 2H2BA 1GQ5A 3I4WA 2IWOA 2KYLA 1K32A 2JREA 2CSJA 2ENOA 4E35A 2I4SA 2OCSA 3JXTA 5HDYA 1X5RA 1IHJA 4NXRA 5E22A 2OGPA 4JOKA 4P2AB 3QO6A 2E7KA 2KAWA 5HF1A
chains in the Genus database with same CATH topology
2LUIA 2YT7A 1YBOA 2HE4A 2D92A 4JOGA 5G1DA 2JIKA 2YT8A 1U37A 2UZCA 3ID3A 5E11A 2Z9IA 2F0AA 2EEGA 1B8QA 3SHUA 2JXOA 3VQFA 5ILBA 2KBSA 3MH4A 2QKTA 2MHOA 4R2ZA 2AWUA 1QAVB 4NMRA 1W9EA 4Q2OA 1M5ZA 3FY5A 1Y8TA 2MX6A 2ZPMA 1N99A 1G9OA 3CBYA 4HOPA 5HJ1A 1X6DA 2LA8A 3SUZA 1WI2A 5B6LA 4N6XA 2DKRA 2M0UA 2H2CA 2KQFA 1WI4A 5G1EA 3ID2A 4MPAA 3ZRTA 3R68A 2FN5A 1WF8A 2EGOA 2EEHA 4L8NA 3KDGA 5E6PB 3TSZA 2AWWA 3GDVA 2G5MB 4NMVA 2VPHA 2VSPA 2M0ZA 2EGNA 3NFLA 2DMZA 3GDSA 4Q3HA 2QKVA 1Z87A 4Q6SA 4NMTA 1KY9A 1RZXA 1IU2A 1TE0A 1BE9A 2EEIA 2KA9A 2WL7A 5HEDA 3CBZA 2OMJA 3KZDA 4NMPA 1UEPA 4K75A 2EJYA 5A2PA 1UJVA 3NFKA 1W9QA 2KOMA 3SOEA 3KDKA 3PDVA 1N6DA 2DC2A 1RY4A 4KFVA 3STJA 3RL7A 3R0HA 2JINA 2JSNA 2L4TA 4Q6HA 2M0VA 3CC0A 1UHPA 4JOJA 5HEBA 2JILA 4NMSA 4K78A 5E1YA 2V1WA 3NGHA 2AINA 3LNXA 1WFGA 2L4SA 1W9OA 5HF4A 2M10A 1WHDA 2CS5A 3QDOA 2BYGA 2Q3GA 2PA1A 2VRFA 1N7TA 5B42A 3CBXA 2IWNA 5GNDA 1FC9A 1IU0A 5EZ0A 3AXAA 4JJ0A 2DLUA 3TSVA 3EGGC 1UJUA 5HEYA 1GQ4A 3RL8A 2H3MA 4XHVA 3KZEA 2RCZA 1VB7A 2R4HA 1QAVA 3GGEA 2PKTA 3PDZA 1WFVA 2REYA 4Q2QA 1X8SA 3OTPA 3NCVA 2Z17A 1WJLA 1I92A 5E21A 1MC7A 4Z8JA 1OBYA 5IL9A 3GDUA 1U39A 3CH8A 4NMQA 2EXGA 1V5LA 1WIFA 2P3WA 1NTEA 3WKLA 4JOPA 2I0IA 3QIKA 4REYA 2FCFA 3QJMA 4FGMA 2L97A 4KFWA 4GVCA 2IWQA 4IC6A 1LCYA 4P0CA 4GHNA 2VSVA 3E17A 3CS0A 2QT5A 1RGWA 1QAUA 2I04A 3QGLA 2QBWA 2G2LA 3BPUA 1UM1A 1TQ3A 3PS4A 2DLSA 5I7ZA 1I16A 3GJ9A 3RLEA 5H3JA 4E3BA 2OZFA 3CYYA 2KRGA 1WH1A 3DJ3A 4NXQA 1KEFA 2K20A 5D13A 2HGAA 3GABA 4RI0A 1Q3PA 1N7EA 4Q2PA 2OSGA 3K1RA 2LC7A 2QG1A 3I1EA 4NMOA 4WYTA 3DORA 2HE2A 3TMHA 1UM7A 2PNTA 2EV8A 5HFFA 2OPGA 1UJDA 4K76A 2GZVA 2RRMA 4WYUA 2DB5A 3R69A 2QKUA 1SOZA 1Y7NA 2FE5A 2PDZA 3QJNA 4JOHA 2CSSA 4JORA 1GM1A 1FCFA 2I1NA 3HVQC 1UFXA 2O2TA 1D5GA 2JWEA 5HFBA 4LMMA 4Q2NA 4PQWA 1V5QA 4OEOA 2W7RA 1MFLA 2ZPLA 4NXPA 3MH7A 5HETA 2KL1A 1Q7XA 1V62A 1X5NA 1X9ZA 1X45A 4JOFA 1KWAA 4F8KA 2DJTA 2FNEA 2OS6A 2KV8A 3GSLA 2EEJA 2IWPA 3O46A 1T2MA 3TSWA 1VJ6A 2W4FA 5HFDA 1WG6A 2V90A 4Z33A 2M0TA 5HFEA 1UEQA 1SOTA 5HFCA 1FC7A 2KJPA 1Z86A 2VWRA 4NNMA 3HPMA 4G69A 1P1DA 2VZ5A 4E34A 4YDPA 5F3XA 3SFJA 3PV5A 1V1TA 1MFGA 1Q3OA 2I0LA 1UEZA 2D8IA 2KOHA 4O06A 1ZOKA 1U3BA 2EHRA 2Q9VA 2F5YA 4JOEA 3KHFA 1RGRA 1U38A 2EGKA 3HPKA 1X5QA 4YYXA 2X7ZA 5JXBA 4HOPB 3EGHC 3K50A 2DAZA 1V6BA 3PV2A 1N7FA 5FHTA 1FC6A 4FLNA 5FB8C 1TP5A 3SHWA 2PZDA 1UITA 4EDJA 4UU6A 2KPLA 2OQSA 3DJAA 3L4FD 2R3YA 2DM8A 3DJ1A 3ID1A 1L6OA 3VQGA 2KG2A 2LC6A 2EDPA 4H11A 1QLCA 1VAEA 4AMHA 1N6FA 2EAQA 1PDRA 3PV4A 3I18A 4OAJA 3B76A 2EDZA 4K72A 5DTHA 5GLJA 3WKMA 3GCOA 3GCNA 4K6YA 2D90A 1OBXA 2AWXA 2H3LA 2PKUA 1UF1A 1NF3C 2LOBA 2YUBA 1XZ9A 3LNYA 1R6JA 4JJ3A 3ID4A 2KOJA 1ZUBA 2JOAA 3DIWA 1N6EA 2K1ZA 1OZIA 3QE1A 2M3MA 1OBZA 1TP3A 4UU5A 1WHAA 1VCWA 5EYZA 2KJKA 1VA8A 2I6VA 4GVDA 2YUYA 3MH6A 1P1EA 4OEPA 5F67A 2KPKA 2KJDA 2EDVA 3O5NA 3OU0A 2YTWA 1UEWA 4NNLA 1BFEA 1WF7A 2GEFA 4JL7A 3K82A 2H2BA 1GQ5A 3I4WA 2IWOA 2KYLA 1K32A 2JREA 2CSJA 2ENOA 4E35A 2I4SA 2OCSA 3JXTA 5HDYA 1X5RA 1IHJA 4NXRA 5E22A 2OGPA 4JOKA 4P2AB 3QO6A 2E7KA 2KAWA 5HF1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LUI A;  2YT7 A;  1YBO A;  2HE4 A;  2D92 A;  4JOG A;  5G1D A;  2JIK A;  2YT8 A;  1U37 A;  2UZC A;  3ID3 A;  5E11 A;  2Z9I A;  2F0A A;  2EEG A;  1B8Q A;  3SHU A;  2JXO A;  3VQF A;  2KBS A;  3MH4 A;  2QKT A;  2MHO A;  4R2Z A;  2AWU A;  1QAV B;  4NMR A;  1W9E A;  4Q2O A;  1M5Z A;  3FY5 A;  1Y8T A;  2MX6 A;  2ZPM A;  1N99 A;  1G9O A;  3CBY A;  4HOP A;  5HJ1 A;  1X6D A;  2LA8 A;  3SUZ A;  1WI2 A;  5B6L A;  4N6X A;  2DKR A;  2M0U A;  2H2C A;  2KQF A;  1WI4 A;  5G1E A;  3ID2 A;  4MPA A;  3ZRT A;  3R68 A;  2FN5 A;  1WF8 A;  2EGO A;  2EEH A;  4L8N A;  5E6P B;  3TSZ A;  2AWW A;  3GDV A;  2G5M B;  4NMV A;  2VPH A;  2VSP A;  2M0Z A;  2EGN A;  3NFL A;  2DMZ A;  3GDS A;  4Q3H A;  2QKV A;  1Z87 A;  4Q6S A;  4NMT A;  1KY9 A;  1RZX A;  1IU2 A;  1TE0 A;  1BE9 A;  2EEI A;  2KA9 A;  2WL7 A;  5HED A;  3CBZ A;  2OMJ A;  3KZD A;  4NMP A;  1UEP A;  4K75 A;  2EJY A;  5A2P A;  1UJV A;  3NFK A;  1W9Q A;  2KOM A;  3SOE A;  3PDV A;  1N6D A;  2DC2 A;  1RY4 A;  4KFV A;  3STJ A;  3RL7 A;  3R0H A;  2JIN A;  2L4T A;  4Q6H A;  2M0V A;  3CC0 A;  1UHP A;  4JOJ A;  5HEB A;  2JIL A;  4NMS A;  4K78 A;  5E1Y A;  2V1W A;  3NGH A;  2AIN A;  3LNX A;  1WFG A;  2L4S A;  1W9O A;  5HF4 A;  2M10 A;  1WHD A;  2CS5 A;  3QDO A;  2BYG A;  2Q3G A;  2PA1 A;  2VRF A;  1N7T A;  3CBX A;  2IWN A;  5GND A;  1FC9 A;  1IU0 A;  5EZ0 A;  3AXA A;  2DLU A;  3TSV A;  3EGG C;  1UJU A;  5HEY A;  1GQ4 A;  3RL8 A;  2H3M A;  4XHV A;  3KZE A;  2RCZ A;  1VB7 A;  2R4H A;  1QAV A;  3GGE A;  2PKT A;  3PDZ A;  1WFV A;  2REY A;  4Q2Q A;  1X8S A;  3OTP A;  2Z17 A;  1WJL A;  1I92 A;  5E21 A;  1MC7 A;  4Z8J A;  1OBY A;  3GDU A;  1U39 A;  3CH8 A;  4NMQ A;  2EXG A;  1V5L A;  1WIF A;  2P3W A;  1NTE A;  3WKL A;  4JOP A;  2I0I A;  3QIK A;  4REY A;  2FCF A;  3QJM A;  4FGM A;  2L97 A;  4KFW A;  4GVC A;  2IWQ A;  4IC6 A;  1LCY A;  4P0C A;  4GHN A;  2VSV A;  3E17 A;  3CS0 A;  2QT5 A;  1RGW A;  1QAU A;  2I04 A;  3QGL A;  2QBW A;  2G2L A;  3BPU A;  1UM1 A;  1TQ3 A;  3PS4 A;  2DLS A;  5I7Z A;  1I16 A;  3GJ9 A;  3RLE A;  5H3J A;  4E3B A;  2OZF A;  3CYY A;  2KRG A;  1WH1 A;  3DJ3 A;  4NXQ A;  1KEF A;  2K20 A;  5D13 A;  2HGA A;  4RI0 A;  1Q3P A;  1N7E A;  4Q2P A;  2OSG A;  3K1R A;  2LC7 A;  2QG1 A;  3I1E A;  4NMO A;  4WYT A;  3DOR A;  2HE2 A;  3TMH A;  1UM7 A;  2PNT A;  2EV8 A;  5HFF A;  2OPG A;  1UJD A;  4K76 A;  2GZV A;  2RRM A;  4WYU A;  2DB5 A;  3R69 A;  2QKU A;  1SOZ A;  1Y7N A;  2FE5 A;  2PDZ A;  3QJN A;  4JOH A;  2CSS A;  4JOR A;  1GM1 A;  1FCF A;  2I1N A;  3HVQ C;  1UFX A;  2O2T A;  1D5G A;  2JWE A;  5HFB A;  4LMM A;  4Q2N A;  4PQW A;  1V5Q A;  4OEO A;  2W7R A;  1MFL A;  2ZPL A;  4NXP A;  3MH7 A;  5HET A;  2KL1 A;  1Q7X A;  1V62 A;  1X5N A;  1X45 A;  4JOF A;  1KWA A;  4F8K A;  2DJT A;  2FNE A;  2OS6 A;  2KV8 A;  3GSL A;  2EEJ A;  2IWP A;  3O46 A;  1T2M A;  3TSW A;  1VJ6 A;  2W4F A;  5HFD A;  1WG6 A;  2V90 A;  4Z33 A;  2M0T A;  5HFE A;  1UEQ A;  1SOT A;  5HFC A;  1FC7 A;  2KJP A;  1Z86 A;  2VWR A;  4NNM A;  3HPM A;  4G69 A;  1P1D A;  2VZ5 A;  4E34 A;  4YDP A;  5F3X A;  3SFJ A;  3PV5 A;  1V1T A;  1MFG A;  1Q3O A;  2I0L A;  1UEZ A;  2D8I A;  2KOH A;  4O06 A;  1ZOK A;  1U3B A;  2EHR A;  2Q9V A;  2F5Y A;  4JOE A;  3KHF A;  1RGR A;  1U38 A;  2EGK A;  3HPK A;  1X5Q A;  4YYX A;  2X7Z A;  5JXB A;  4HOP B;  3EGH C;  3K50 A;  2DAZ A;  1V6B A;  3PV2 A;  1N7F A;  5FHT A;  1FC6 A;  5FB8 C;  1TP5 A;  3SHW A;  2PZD A;  1UIT A;  4EDJ A;  4UU6 A;  2KPL A;  2OQS A;  3DJA A;  3L4F D;  2R3Y A;  2DM8 A;  3DJ1 A;  3ID1 A;  1L6O A;  3VQG A;  2KG2 A;  2LC6 A;  2EDP A;  4H11 A;  1QLC A;  1VAE A;  4AMH A;  1N6F A;  2EAQ A;  1PDR A;  3PV4 A;  3I18 A;  4OAJ A;  3B76 A;  2EDZ A;  4K72 A;  5DTH A;  5GLJ A;  3WKM A;  3GCO A;  3GCN A;  4K6Y A;  2D90 A;  1OBX A;  2AWX A;  2H3L A;  2PKU A;  1UF1 A;  1NF3 C;  2LOB A;  2YUB A;  1XZ9 A;  3LNY A;  1R6J A;  3ID4 A;  2KOJ A;  1ZUB A;  2JOA A;  3DIW A;  1N6E A;  2K1Z A;  1OZI A;  3QE1 A;  2M3M A;  1OBZ A;  1TP3 A;  4UU5 A;  1WHA A;  1VCW A;  5EYZ A;  2KJK A;  1VA8 A;  2I6V A;  4GVD A;  2YUY A;  3MH6 A;  1P1E A;  4OEP A;  5F67 A;  2KPK A;  2KJD A;  2EDV A;  3O5N A;  3OU0 A;  2YTW A;  1UEW A;  4NNL A;  1BFE A;  1WF7 A;  4JL7 A;  3K82 A;  2H2B A;  1GQ5 A;  3I4W A;  2IWO A;  2KYL A;  1K32 A;  2JRE A;  2CSJ A;  2ENO A;  4E35 A;  2I4S A;  2OCS A;  3JXT A;  5HDY A;  1X5R A;  1IHJ A;  4NXR A;  5E22 A;  2OGP A;  4JOK A;  4P2A B;  3QO6 A;  2E7K A;  2KAW A;  5HF1 A; 
#chains in the Genus database with same CATH topology
 2LUI A;  2YT7 A;  1YBO A;  2HE4 A;  2D92 A;  4JOG A;  5G1D A;  2JIK A;  2YT8 A;  1U37 A;  2UZC A;  3ID3 A;  5E11 A;  2Z9I A;  2F0A A;  2EEG A;  1B8Q A;  3SHU A;  2JXO A;  3VQF A;  5ILB A;  2KBS A;  3MH4 A;  2QKT A;  2MHO A;  4R2Z A;  2AWU A;  1QAV B;  4NMR A;  1W9E A;  4Q2O A;  1M5Z A;  3FY5 A;  1Y8T A;  2MX6 A;  2ZPM A;  1N99 A;  1G9O A;  3CBY A;  4HOP A;  5HJ1 A;  1X6D A;  2LA8 A;  3SUZ A;  1WI2 A;  5B6L A;  4N6X A;  2DKR A;  2M0U A;  2H2C A;  2KQF A;  1WI4 A;  5G1E A;  3ID2 A;  4MPA A;  3ZRT A;  3R68 A;  2FN5 A;  1WF8 A;  2EGO A;  2EEH A;  4L8N A;  3KDG A;  5E6P B;  3TSZ A;  2AWW A;  3GDV A;  2G5M B;  4NMV A;  2VPH A;  2VSP A;  2M0Z A;  2EGN A;  3NFL A;  2DMZ A;  3GDS A;  4Q3H A;  2QKV A;  1Z87 A;  4Q6S A;  4NMT A;  1KY9 A;  1RZX A;  1IU2 A;  1TE0 A;  1BE9 A;  2EEI A;  2KA9 A;  2WL7 A;  5HED A;  3CBZ A;  2OMJ A;  3KZD A;  4NMP A;  1UEP A;  4K75 A;  2EJY A;  5A2P A;  1UJV A;  3NFK A;  1W9Q A;  2KOM A;  3SOE A;  3KDK A;  3PDV A;  1N6D A;  2DC2 A;  1RY4 A;  4KFV A;  3STJ A;  3RL7 A;  3R0H A;  2JIN A;  2JSN A;  2L4T A;  4Q6H A;  2M0V A;  3CC0 A;  1UHP A;  4JOJ A;  5HEB A;  2JIL A;  4NMS A;  4K78 A;  5E1Y A;  2V1W A;  3NGH A;  2AIN A;  3LNX A;  1WFG A;  2L4S A;  1W9O A;  5HF4 A;  2M10 A;  1WHD A;  2CS5 A;  3QDO A;  2BYG A;  2Q3G A;  2PA1 A;  2VRF A;  1N7T A;  5B42 A;  3CBX A;  2IWN A;  5GND A;  1FC9 A;  1IU0 A;  5EZ0 A;  3AXA A;  4JJ0 A;  2DLU A;  3TSV A;  3EGG C;  1UJU A;  5HEY A;  1GQ4 A;  3RL8 A;  2H3M A;  4XHV A;  3KZE A;  2RCZ A;  1VB7 A;  2R4H A;  1QAV A;  3GGE A;  2PKT A;  3PDZ A;  1WFV A;  2REY A;  4Q2Q A;  1X8S A;  3OTP A;  3NCV A;  2Z17 A;  1WJL A;  1I92 A;  5E21 A;  1MC7 A;  4Z8J A;  1OBY A;  5IL9 A;  3GDU A;  1U39 A;  3CH8 A;  4NMQ A;  2EXG A;  1V5L A;  1WIF A;  2P3W A;  1NTE A;  3WKL A;  4JOP A;  2I0I A;  3QIK A;  4REY A;  2FCF A;  3QJM A;  4FGM A;  2L97 A;  4KFW A;  4GVC A;  2IWQ A;  4IC6 A;  1LCY A;  4P0C A;  4GHN A;  2VSV A;  3E17 A;  3CS0 A;  2QT5 A;  1RGW A;  1QAU A;  2I04 A;  3QGL A;  2QBW A;  2G2L A;  3BPU A;  1UM1 A;  1TQ3 A;  3PS4 A;  2DLS A;  5I7Z A;  1I16 A;  3GJ9 A;  3RLE A;  5H3J A;  4E3B A;  2OZF A;  3CYY A;  2KRG A;  1WH1 A;  3DJ3 A;  4NXQ A;  1KEF A;  2K20 A;  5D13 A;  2HGA A;  3GAB A;  4RI0 A;  1Q3P A;  1N7E A;  4Q2P A;  2OSG A;  3K1R A;  2LC7 A;  2QG1 A;  3I1E A;  4NMO A;  4WYT A;  3DOR A;  2HE2 A;  3TMH A;  1UM7 A;  2PNT A;  2EV8 A;  5HFF A;  2OPG A;  1UJD A;  4K76 A;  2GZV A;  2RRM A;  4WYU A;  2DB5 A;  3R69 A;  2QKU A;  1SOZ A;  1Y7N A;  2FE5 A;  2PDZ A;  3QJN A;  4JOH A;  2CSS A;  4JOR A;  1GM1 A;  1FCF A;  2I1N A;  3HVQ C;  1UFX A;  2O2T A;  1D5G A;  2JWE A;  5HFB A;  4LMM A;  4Q2N A;  4PQW A;  1V5Q A;  4OEO A;  2W7R A;  1MFL A;  2ZPL A;  4NXP A;  3MH7 A;  5HET A;  2KL1 A;  1Q7X A;  1V62 A;  1X5N A;  1X9Z A;  1X45 A;  4JOF A;  1KWA A;  4F8K A;  2DJT A;  2FNE A;  2OS6 A;  2KV8 A;  3GSL A;  2EEJ A;  2IWP A;  3O46 A;  1T2M A;  3TSW A;  1VJ6 A;  2W4F A;  5HFD A;  1WG6 A;  2V90 A;  4Z33 A;  2M0T A;  5HFE A;  1UEQ A;  1SOT A;  5HFC A;  1FC7 A;  2KJP A;  1Z86 A;  2VWR A;  4NNM A;  3HPM A;  4G69 A;  1P1D A;  2VZ5 A;  4E34 A;  4YDP A;  5F3X A;  3SFJ A;  3PV5 A;  1V1T A;  1MFG A;  1Q3O A;  2I0L A;  1UEZ A;  2D8I A;  2KOH A;  4O06 A;  1ZOK A;  1U3B A;  2EHR A;  2Q9V A;  2F5Y A;  4JOE A;  3KHF A;  1RGR A;  1U38 A;  2EGK A;  3HPK A;  1X5Q A;  4YYX A;  2X7Z A;  5JXB A;  4HOP B;  3EGH C;  3K50 A;  2DAZ A;  1V6B A;  3PV2 A;  1N7F A;  5FHT A;  1FC6 A;  4FLN A;  5FB8 C;  1TP5 A;  3SHW A;  2PZD A;  1UIT A;  4EDJ A;  4UU6 A;  2KPL A;  2OQS A;  3DJA A;  3L4F D;  2R3Y A;  2DM8 A;  3DJ1 A;  3ID1 A;  1L6O A;  3VQG A;  2KG2 A;  2LC6 A;  2EDP A;  4H11 A;  1QLC A;  1VAE A;  4AMH A;  1N6F A;  2EAQ A;  1PDR A;  3PV4 A;  3I18 A;  4OAJ A;  3B76 A;  2EDZ A;  4K72 A;  5DTH A;  5GLJ A;  3WKM A;  3GCO A;  3GCN A;  4K6Y A;  2D90 A;  1OBX A;  2AWX A;  2H3L A;  2PKU A;  1UF1 A;  1NF3 C;  2LOB A;  2YUB A;  1XZ9 A;  3LNY A;  1R6J A;  4JJ3 A;  3ID4 A;  2KOJ A;  1ZUB A;  2JOA A;  3DIW A;  1N6E A;  2K1Z A;  1OZI A;  3QE1 A;  2M3M A;  1OBZ A;  1TP3 A;  4UU5 A;  1WHA A;  1VCW A;  5EYZ A;  2KJK A;  1VA8 A;  2I6V A;  4GVD A;  2YUY A;  3MH6 A;  1P1E A;  4OEP A;  5F67 A;  2KPK A;  2KJD A;  2EDV A;  3O5N A;  3OU0 A;  2YTW A;  1UEW A;  4NNL A;  1BFE A;  1WF7 A;  2GEF A;  4JL7 A;  3K82 A;  2H2B A;  1GQ5 A;  3I4W A;  2IWO A;  2KYL A;  1K32 A;  2JRE A;  2CSJ A;  2ENO A;  4E35 A;  2I4S A;  2OCS A;  3JXT A;  5HDY A;  1X5R A;  1IHJ A;  4NXR A;  5E22 A;  2OGP A;  4JOK A;  4P2A B;  3QO6 A;  2E7K A;  2KAW A;  5HF1 A; 
#chains in the Genus database with same CATH homology
 2LUI A;  2YT7 A;  1YBO A;  2HE4 A;  2D92 A;  4JOG A;  5G1D A;  2JIK A;  2YT8 A;  1U37 A;  2UZC A;  3ID3 A;  5E11 A;  2Z9I A;  2F0A A;  2EEG A;  1B8Q A;  3SHU A;  2JXO A;  3VQF A;  5ILB A;  2KBS A;  3MH4 A;  2QKT A;  2MHO A;  4R2Z A;  2AWU A;  1QAV B;  4NMR A;  1W9E A;  4Q2O A;  1M5Z A;  3FY5 A;  1Y8T A;  2MX6 A;  2ZPM A;  1N99 A;  1G9O A;  3CBY A;  4HOP A;  5HJ1 A;  1X6D A;  2LA8 A;  3SUZ A;  1WI2 A;  5B6L A;  4N6X A;  2DKR A;  2M0U A;  2H2C A;  2KQF A;  1WI4 A;  5G1E A;  3ID2 A;  4MPA A;  3ZRT A;  3R68 A;  2FN5 A;  1WF8 A;  2EGO A;  2EEH A;  4L8N A;  3KDG A;  5E6P B;  3TSZ A;  2AWW A;  3GDV A;  2G5M B;  4NMV A;  2VPH A;  2VSP A;  2M0Z A;  2EGN A;  3NFL A;  2DMZ A;  3GDS A;  4Q3H A;  2QKV A;  1Z87 A;  4Q6S A;  4NMT A;  1KY9 A;  1RZX A;  1IU2 A;  1TE0 A;  1BE9 A;  2EEI A;  2KA9 A;  2WL7 A;  5HED A;  3CBZ A;  2OMJ A;  3KZD A;  4NMP A;  1UEP A;  4K75 A;  2EJY A;  5A2P A;  1UJV A;  3NFK A;  1W9Q A;  2KOM A;  3SOE A;  3KDK A;  3PDV A;  1N6D A;  2DC2 A;  1RY4 A;  4KFV A;  3STJ A;  3RL7 A;  3R0H A;  2JIN A;  2JSN A;  2L4T A;  4Q6H A;  2M0V A;  3CC0 A;  1UHP A;  4JOJ A;  5HEB A;  2JIL A;  4NMS A;  4K78 A;  5E1Y A;  2V1W A;  3NGH A;  2AIN A;  3LNX A;  1WFG A;  2L4S A;  1W9O A;  5HF4 A;  2M10 A;  1WHD A;  2CS5 A;  3QDO A;  2BYG A;  2Q3G A;  2PA1 A;  2VRF A;  1N7T A;  5B42 A;  3CBX A;  2IWN A;  5GND A;  1FC9 A;  1IU0 A;  5EZ0 A;  3AXA A;  4JJ0 A;  2DLU A;  3TSV A;  3EGG C;  1UJU A;  5HEY A;  1GQ4 A;  3RL8 A;  2H3M A;  4XHV A;  3KZE A;  2RCZ A;  1VB7 A;  2R4H A;  1QAV A;  3GGE A;  2PKT A;  3PDZ A;  1WFV A;  2REY A;  4Q2Q A;  1X8S A;  3OTP A;  3NCV A;  2Z17 A;  1WJL A;  1I92 A;  5E21 A;  1MC7 A;  4Z8J A;  1OBY A;  5IL9 A;  3GDU A;  1U39 A;  3CH8 A;  4NMQ A;  2EXG A;  1V5L A;  1WIF A;  2P3W A;  1NTE A;  3WKL A;  4JOP A;  2I0I A;  3QIK A;  4REY A;  2FCF A;  3QJM A;  4FGM A;  2L97 A;  4KFW A;  4GVC A;  2IWQ A;  4IC6 A;  1LCY A;  4P0C A;  4GHN A;  2VSV A;  3E17 A;  3CS0 A;  2QT5 A;  1RGW A;  1QAU A;  2I04 A;  3QGL A;  2QBW A;  2G2L A;  3BPU A;  1UM1 A;  1TQ3 A;  3PS4 A;  2DLS A;  5I7Z A;  1I16 A;  3GJ9 A;  3RLE A;  5H3J A;  4E3B A;  2OZF A;  3CYY A;  2KRG A;  1WH1 A;  3DJ3 A;  4NXQ A;  1KEF A;  2K20 A;  5D13 A;  2HGA A;  3GAB A;  4RI0 A;  1Q3P A;  1N7E A;  4Q2P A;  2OSG A;  3K1R A;  2LC7 A;  2QG1 A;  3I1E A;  4NMO A;  4WYT A;  3DOR A;  2HE2 A;  3TMH A;  1UM7 A;  2PNT A;  2EV8 A;  5HFF A;  2OPG A;  1UJD A;  4K76 A;  2GZV A;  2RRM A;  4WYU A;  2DB5 A;  3R69 A;  2QKU A;  1SOZ A;  1Y7N A;  2FE5 A;  2PDZ A;  3QJN A;  4JOH A;  2CSS A;  4JOR A;  1GM1 A;  1FCF A;  2I1N A;  3HVQ C;  1UFX A;  2O2T A;  1D5G A;  2JWE A;  5HFB A;  4LMM A;  4Q2N A;  4PQW A;  1V5Q A;  4OEO A;  2W7R A;  1MFL A;  2ZPL A;  4NXP A;  3MH7 A;  5HET A;  2KL1 A;  1Q7X A;  1V62 A;  1X5N A;  1X9Z A;  1X45 A;  4JOF A;  1KWA A;  4F8K A;  2DJT A;  2FNE A;  2OS6 A;  2KV8 A;  3GSL A;  2EEJ A;  2IWP A;  3O46 A;  1T2M A;  3TSW A;  1VJ6 A;  2W4F A;  5HFD A;  1WG6 A;  2V90 A;  4Z33 A;  2M0T A;  5HFE A;  1UEQ A;  1SOT A;  5HFC A;  1FC7 A;  2KJP A;  1Z86 A;  2VWR A;  4NNM A;  3HPM A;  4G69 A;  1P1D A;  2VZ5 A;  4E34 A;  4YDP A;  5F3X A;  3SFJ A;  3PV5 A;  1V1T A;  1MFG A;  1Q3O A;  2I0L A;  1UEZ A;  2D8I A;  2KOH A;  4O06 A;  1ZOK A;  1U3B A;  2EHR A;  2Q9V A;  2F5Y A;  4JOE A;  3KHF A;  1RGR A;  1U38 A;  2EGK A;  3HPK A;  1X5Q A;  4YYX A;  2X7Z A;  5JXB A;  4HOP B;  3EGH C;  3K50 A;  2DAZ A;  1V6B A;  3PV2 A;  1N7F A;  5FHT A;  1FC6 A;  4FLN A;  5FB8 C;  1TP5 A;  3SHW A;  2PZD A;  1UIT A;  4EDJ A;  4UU6 A;  2KPL A;  2OQS A;  3DJA A;  3L4F D;  2R3Y A;  2DM8 A;  3DJ1 A;  3ID1 A;  1L6O A;  3VQG A;  2KG2 A;  2LC6 A;  2EDP A;  4H11 A;  1QLC A;  1VAE A;  4AMH A;  1N6F A;  2EAQ A;  1PDR A;  3PV4 A;  3I18 A;  4OAJ A;  3B76 A;  2EDZ A;  4K72 A;  5DTH A;  5GLJ A;  3WKM A;  3GCO A;  3GCN A;  4K6Y A;  2D90 A;  1OBX A;  2AWX A;  2H3L A;  2PKU A;  1UF1 A;  1NF3 C;  2LOB A;  2YUB A;  1XZ9 A;  3LNY A;  1R6J A;  4JJ3 A;  3ID4 A;  2KOJ A;  1ZUB A;  2JOA A;  3DIW A;  1N6E A;  2K1Z A;  1OZI A;  3QE1 A;  2M3M A;  1OBZ A;  1TP3 A;  4UU5 A;  1WHA A;  1VCW A;  5EYZ A;  2KJK A;  1VA8 A;  2I6V A;  4GVD A;  2YUY A;  3MH6 A;  1P1E A;  4OEP A;  5F67 A;  2KPK A;  2KJD A;  2EDV A;  3O5N A;  3OU0 A;  2YTW A;  1UEW A;  4NNL A;  1BFE A;  1WF7 A;  2GEF A;  4JL7 A;  3K82 A;  2H2B A;  1GQ5 A;  3I4W A;  2IWO A;  2KYL A;  1K32 A;  2JRE A;  2CSJ A;  2ENO A;  4E35 A;  2I4S A;  2OCS A;  3JXT A;  5HDY A;  1X5R A;  1IHJ A;  4NXR A;  5E22 A;  2OGP A;  4JOK A;  4P2A B;  3QO6 A;  2E7K A;  2KAW A;  5HF1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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