4HOPB

Crystal structure of the computationally designed nnos-syntrophin complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
120
structure length
120
Chain Sequence
FGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLEMTFTGDGTPKTIRVTQP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition.
pubmed doi rcsb
molecule tags Membrane protein/oxidoreductase
source organism Mus musculus
molecule keywords Alpha-1-syntrophin
total genus 24
structure length 120
sequence length 120
chains with identical sequence D, F
ec nomenclature ec 1.14.13.39: Nitric-oxide synthase (NADPH).
pdb deposition date 2012-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4hopB00
1UEWA 2KAWA 2FN5A 5FB8C 2KBSA 2YT7A 2DB5A 2JILA 1Z86A 2CSSA 3NFKA 3I18A 3QJNA 1GM1A 2VPHA 2R4HA 3OTPA 3DORA 3TSVA 5A2PA 1MFLA 1UEPA 1V6BA 2EV8A 4NMPA 3QE1A 2OS6A 2LUIA 4OEOA 4Q6SA 1Y7NA 2KA9A 4OEPA 5HF4A 2OPGA 1P1EA 2RRMA 2KPKA 2ENOA 4NMOA 4Q2NA 2EDZA 4JOPA 1M5ZA 3GGEA 3L4FD 2EEGA 1QAVB 5E1YA 3EGGC 3GDSA 2G5MB 5I7ZA 5GNDA 1RZXA 5HEYA 1FC7A 1GQ4A 1FC6A 1OBYA 3STJA 3R0HA 4L8NA 2KJPA 1VB7A 1FC9A 2EAQA 2PKTA 1OBXA 1RGRA 4NXQA 1D5GA 4JOGA 2L97A 1Q7XA 1WG6A 3FY5A 3R68A 4KFWA 4NMQA 3CBZA 1VA8A 4NMTA 3R69A 1UM7A 2KOJA 3PV5A 5HDYA 4WYTA 3WKLA 3JXTA 2W4FA 1WF7A 1VCWA 3MH4A 2YUBA 3LNYA 1U37A 1W9OA 2I0IA 3NGHA 3EGHC 2QKVA 3ID3A 5HETA 3CS0A 1X8SA 1Z87A 4OAJA 2VRFA 1WH1A 4Q2QA 5HFDA 2EEJA 4Z33A 2KJDA 2EDVA 1N7FA 3MH6A 4N6XA 1NTEA 5HFEA 2JINA 2EGNA 2I1NA 2X7ZA 2OMJA 4Q3HA 3OU0A 3SHUA 2AINA 3LNXA 1KEFA 2E7KA 5G1EA 4H11A 2MX6A 2V1WA 5F67A 1IU0A 4NXPA 5E6PB 2AWWA 1Y8TA 2F5YA 3HPMA 1RGWA 3PV4A 4HOPA 3B76A 2JOAA 2VSPA 4JOEA 4NXRA 2ZPLA 3K82A 4JOKA 3CBXA 2KQFA 4XHVA 3GJ9A 2W7RA 3SUZA 2EEHA 5E11A 2UZCA 4IC6A 2LOBA 2OSGA 5FHTA 2K1ZA 1WI2A 1TP5A 1WHAA 2K20A 1V1TA 3CC0A 1BFEA 2EGOA 3VQGA 3QIKA 2M0UA 2I4SA 1SOZA 1U39A 1IHJA 4EDJA 4RI0A 3TSZA 2FCFA 2QKTA 1U3BA 4REYA 3SFJA 2IWQA 1WI4A 4PQWA 2FNEA 1Q3OA 5JXBA 2KG2A 2KV8A 1UJVA 2REYA 2GZVA 2PKUA 1T2MA 5HEBA 3CYYA 1TE0A 1VJ6A 2PA1A 5HFCA 5GLJA 1YBOA 4MPAA 1B8QA 4P2AB 1UEZA 4K78A 1PDRA 2ZPMA 1UHPA 2OZFA 3GDVA 4E35A 1I92A 3PDVA 2DAZA 5E22A 4G69A 1QLCA 1WIFA 5B6LA 2Z17A 1UEQA 1OZIA 1G9OA 4K75A 4Q6HA 2I6VA 1NF3C 4FGMA 1XZ9A 2AWUA 2MHOA 1L6OA 2AWXA 2KJKA 3PDZA 2KOHA 1N6FA 2QBWA 3O5NA 4R2ZA 2KPLA 1V62A 3ID2A 2CSJA 2JWEA 5G1DA 1K32A 1LCYA 1KWAA 3MH7A 3WKMA 3ID4A 2QT5A 1N6EA 2FE5A 2M0VA 3VQFA 1ZUBA 3K1RA 1GQ5A 2JXOA 3QGLA 4HOPB 4JOHA 2HGAA 3GSLA 2QKUA 2EDPA 2EJYA 4LMMA 2DC2A 1WFGA 4K72A 2Z9IA 3HPKA 2VSVA 4JOFA 1IU2A 2H2BA 2OGPA 4NMVA 4JOJA 4NMRA 2DLUA 2HE2A 2D92A 1WFVA 3RL7A 1TQ3A 2M0TA 3ID1A 3TSWA 4F8KA 3KHFA 1V5QA 2V90A 2JIKA 3O46A 1UJUA 5HJ1A 1R6JA 2QG1A 3KZEA 3BPUA 2DJTA 2Q3GA 4K76A 1WF8A 2KL1A 3SOEA 3TMHA 1X5QA 3AXAA 1P1DA 2KOMA 2I0LA 5F3XA 4UU6A 4E3BA 1X6DA 2EXGA 1X45A 4AMHA 4GHNA 5EZ0A 4KFVA 4GVDA 4E34A 4NNLA 2EGKA 4WYUA 5E21A 5H3JA 3HVQC 2M0ZA 2JREA 2H3MA 3DJAA 2DKRA 3DIWA 3K50A 2H2CA 2KYLA 4Q2OA 2IWPA 1W9EA 3I1EA 2M10A 2IWOA 4YYXA 2VWRA 2LA8A 2F0AA 2LC7A 3GCNA 1N6DA 1WJLA 2D90A 2EEIA 5EYZA 2L4SA 1MC7A 1RY4A 1ZOKA 2YT8A 2PNTA 2Q9VA 4JL7A 3PV2A 1QAVA 1N7TA 1MFGA 1U38A 1UM1A 2DLSA 4JORA 2R3YA 3DJ1A 1I16A 1TP3A 3E17A 3CBYA 1BE9A 2O2TA 2HE4A 4UU5A 4O06A 1Q3PA 1V5LA 5HF1A 4Z8JA 3RLEA 4NMSA 3NFLA 2G2LA 2VZ5A 2DMZA 3SHWA 2PDZA 4K6YA 4P0CA 3ZRTA 5HFBA 4NNMA 2LC6A 5D13A 3I4WA 2OCSA 2L4TA 1VAEA 2I04A 2KRGA 2M3MA 2IWNA 1KY9A 1QAUA 2RCZA 2BYGA 2DM8A 3QO6A 2OQSA 1UF1A 3GDUA 1N99A 1UFXA 2YTWA 1W9QA 3PS4A 1X5RA 1OBZA 2D8IA 3DJ3A 5HFFA 1WHDA 1N7EA 2H3LA 3RL8A 2WL7A 2EHRA 3QDOA 2PZDA 3GCOA 1SOTA 2YUYA 4GVCA 4YDPA 5DTHA 4Q2PA 1UITA 3CH8A 1X5NA 3KZDA 2CS5A 5HEDA 1UJDA 1FCFA 3QJMA 2P3WA
chains in the Genus database with same CATH superfamily
1UEWA 2KAWA 2FN5A 5FB8C 2KBSA 2YT7A 2DB5A 2JILA 1Z86A 2CSSA 3NFKA 3I18A 3QJNA 1GM1A 2VPHA 2R4HA 3OTPA 3DORA 3TSVA 5A2PA 1MFLA 1UEPA 1V6BA 2EV8A 4NMPA 3QE1A 2OS6A 2LUIA 4OEOA 4Q6SA 1Y7NA 2KA9A 4OEPA 5HF4A 2OPGA 1P1EA 2RRMA 2KPKA 2ENOA 4NMOA 4Q2NA 2EDZA 4JOPA 1M5ZA 3GGEA 3L4FD 2EEGA 1QAVB 5E1YA 3EGGC 3GDSA 2G5MB 5I7ZA 5GNDA 1RZXA 5HEYA 1FC7A 1GQ4A 1FC6A 1OBYA 3STJA 3R0HA 4L8NA 2KJPA 1VB7A 1FC9A 2EAQA 2PKTA 1OBXA 1RGRA 4NXQA 1D5GA 4JOGA 2L97A 1Q7XA 1WG6A 3FY5A 3R68A 4KFWA 4NMQA 3CBZA 1VA8A 4NMTA 3R69A 1UM7A 2KOJA 3PV5A 5HDYA 4WYTA 3WKLA 3JXTA 2W4FA 1WF7A 1VCWA 3MH4A 2YUBA 3LNYA 1U37A 1W9OA 2I0IA 3NGHA 3EGHC 2QKVA 3ID3A 5HETA 3CS0A 1X8SA 1Z87A 4OAJA 2VRFA 1WH1A 4Q2QA 5HFDA 5ILBA 2EEJA 4Z33A 2KJDA 2EDVA 1N7FA 3MH6A 4N6XA 1NTEA 5HFEA 2JINA 2EGNA 2I1NA 2X7ZA 2OMJA 4Q3HA 3OU0A 3SHUA 2AINA 3LNXA 1KEFA 2E7KA 5G1EA 4H11A 2MX6A 2V1WA 5F67A 1IU0A 4NXPA 5E6PB 2AWWA 1Y8TA 2F5YA 3HPMA 1RGWA 3PV4A 4HOPA 3B76A 2JOAA 2VSPA 4JOEA 4NXRA 2ZPLA 3K82A 4JOKA 3CBXA 2KQFA 4XHVA 3GJ9A 2W7RA 3SUZA 2EEHA 5E11A 2UZCA 4IC6A 2LOBA 2OSGA 5FHTA 2K1ZA 1WI2A 1TP5A 1WHAA 2K20A 1V1TA 3CC0A 1BFEA 2EGOA 3VQGA 3QIKA 2M0UA 2I4SA 1SOZA 1U39A 1IHJA 4EDJA 4RI0A 3TSZA 2FCFA 2QKTA 1U3BA 4REYA 3SFJA 2IWQA 1WI4A 4PQWA 2FNEA 1Q3OA 5JXBA 2KG2A 2KV8A 1UJVA 2REYA 2GZVA 2PKUA 1T2MA 5HEBA 3CYYA 1TE0A 1VJ6A 2PA1A 5HFCA 5GLJA 1YBOA 4MPAA 1B8QA 4P2AB 1UEZA 4K78A 1PDRA 2ZPMA 1UHPA 2OZFA 3GDVA 4E35A 1I92A 3PDVA 2DAZA 5E22A 4G69A 1QLCA 1WIFA 5B6LA 2Z17A 1UEQA 1OZIA 3KDKA 1G9OA 4K75A 4Q6HA 2I6VA 1NF3C 4FGMA 1XZ9A 2AWUA 2MHOA 1L6OA 2AWXA 2KJKA 3PDZA 2KOHA 1N6FA 2QBWA 3O5NA 4R2ZA 2KPLA 1V62A 3ID2A 2CSJA 2JWEA 5G1DA 1K32A 1LCYA 1KWAA 3MH7A 3WKMA 3ID4A 2QT5A 1N6EA 2FE5A 5IL9A 2M0VA 3NCVA 3VQFA 1ZUBA 3K1RA 1GQ5A 2JXOA 3QGLA 4HOPB 4JOHA 2HGAA 3GSLA 2QKUA 2EDPA 2EJYA 4LMMA 2DC2A 1WFGA 4K72A 2Z9IA 3HPKA 2VSVA 4JOFA 1IU2A 2H2BA 2OGPA 4NMVA 4JOJA 4NMRA 2DLUA 2HE2A 2D92A 1WFVA 3RL7A 1TQ3A 2M0TA 3ID1A 3TSWA 4F8KA 3KHFA 1V5QA 2V90A 2JIKA 3O46A 1UJUA 5HJ1A 1R6JA 2QG1A 3KZEA 3BPUA 2DJTA 2Q3GA 4K76A 1WF8A 2KL1A 3SOEA 3TMHA 1X5QA 3AXAA 1P1DA 2KOMA 2I0LA 5F3XA 4UU6A 4E3BA 1X6DA 2EXGA 1X45A 3KDGA 4AMHA 4GHNA 5EZ0A 4KFVA 4GVDA 4E34A 4NNLA 2EGKA 4WYUA 5E21A 5H3JA 3HVQC 2M0ZA 2JREA 2H3MA 3DJAA 2DKRA 4JJ0A 3DIWA 3K50A 2H2CA 2KYLA 4Q2OA 2GEFA 2IWPA 1W9EA 3I1EA 2M10A 2IWOA 4YYXA 2VWRA 2LA8A 2F0AA 2LC7A 3GCNA 1N6DA 1WJLA 2D90A 2EEIA 5EYZA 2L4SA 1MC7A 1RY4A 1ZOKA 2YT8A 2PNTA 2Q9VA 4JL7A 4JJ3A 3PV2A 1QAVA 1X9ZA 1N7TA 1MFGA 1U38A 1UM1A 2DLSA 4JORA 2R3YA 3DJ1A 1I16A 1TP3A 3E17A 3CBYA 1BE9A 2O2TA 2HE4A 4UU5A 4O06A 1Q3PA 1V5LA 5HF1A 5B42A 2JSNA 4Z8JA 3RLEA 4NMSA 3NFLA 2G2LA 2VZ5A 2DMZA 3SHWA 2PDZA 4K6YA 4P0CA 3ZRTA 5HFBA 4NNMA 2LC6A 5D13A 3I4WA 2OCSA 2L4TA 1VAEA 2I04A 2KRGA 2M3MA 2IWNA 1KY9A 1QAUA 3GABA 2RCZA 2BYGA 2DM8A 3QO6A 2OQSA 4FLNA 1UF1A 3GDUA 1N99A 1UFXA 2YTWA 1W9QA 3PS4A 1X5RA 1OBZA 2D8IA 3DJ3A 5HFFA 1WHDA 1N7EA 2H3LA 3RL8A 2WL7A 2EHRA 3QDOA 2PZDA 3GCOA 1SOTA 2YUYA 4GVCA 4YDPA 5DTHA 4Q2PA 1UITA 3CH8A 1X5NA 3KZDA 2CS5A 5HEDA 1UJDA 1FCFA 3QJMA 2P3WA
chains in the Genus database with same CATH topology
1UEWA 2KAWA 2FN5A 5FB8C 2KBSA 2YT7A 2DB5A 2JILA 1Z86A 2CSSA 3NFKA 3I18A 3QJNA 1GM1A 2VPHA 2R4HA 3OTPA 3DORA 3TSVA 5A2PA 1MFLA 1UEPA 1V6BA 2EV8A 4NMPA 3QE1A 2OS6A 2LUIA 4OEOA 4Q6SA 1Y7NA 2KA9A 4OEPA 5HF4A 2OPGA 1P1EA 2RRMA 2KPKA 2ENOA 4NMOA 4Q2NA 2EDZA 4JOPA 1M5ZA 3GGEA 3L4FD 2EEGA 1QAVB 5E1YA 3EGGC 3GDSA 2G5MB 5I7ZA 5GNDA 1RZXA 5HEYA 1FC7A 1GQ4A 1FC6A 1OBYA 3STJA 3R0HA 4L8NA 2KJPA 1VB7A 1FC9A 2EAQA 2PKTA 1OBXA 1RGRA 4NXQA 1D5GA 4JOGA 2L97A 1Q7XA 1WG6A 3FY5A 3R68A 4KFWA 4NMQA 3CBZA 1VA8A 4NMTA 3R69A 1UM7A 2KOJA 3PV5A 5HDYA 4WYTA 3WKLA 3JXTA 2W4FA 1WF7A 1VCWA 3MH4A 2YUBA 3LNYA 1U37A 1W9OA 2I0IA 3NGHA 3EGHC 2QKVA 3ID3A 5HETA 3CS0A 1X8SA 1Z87A 4OAJA 2VRFA 1WH1A 4Q2QA 5HFDA 5ILBA 2EEJA 4Z33A 2KJDA 2EDVA 1N7FA 3MH6A 4N6XA 1NTEA 5HFEA 2JINA 2EGNA 2I1NA 2X7ZA 2OMJA 4Q3HA 3OU0A 3SHUA 2AINA 3LNXA 1KEFA 2E7KA 5G1EA 4H11A 2MX6A 2V1WA 5F67A 1IU0A 4NXPA 5E6PB 2AWWA 1Y8TA 2F5YA 3HPMA 1RGWA 3PV4A 4HOPA 3B76A 2JOAA 2VSPA 4JOEA 4NXRA 2ZPLA 3K82A 4JOKA 3CBXA 2KQFA 4XHVA 3GJ9A 2W7RA 3SUZA 2EEHA 5E11A 2UZCA 4IC6A 2LOBA 2OSGA 5FHTA 2K1ZA 1WI2A 1TP5A 1WHAA 2K20A 1V1TA 3CC0A 1BFEA 2EGOA 3VQGA 3QIKA 2M0UA 2I4SA 1SOZA 1U39A 1IHJA 4EDJA 4RI0A 3TSZA 2FCFA 2QKTA 1U3BA 4REYA 3SFJA 2IWQA 1WI4A 4PQWA 2FNEA 1Q3OA 5JXBA 2KG2A 2KV8A 1UJVA 2REYA 2GZVA 2PKUA 1T2MA 5HEBA 3CYYA 1TE0A 1VJ6A 2PA1A 5HFCA 5GLJA 1YBOA 4MPAA 1B8QA 4P2AB 1UEZA 4K78A 1PDRA 2ZPMA 1UHPA 2OZFA 3GDVA 4E35A 1I92A 3PDVA 2DAZA 5E22A 4G69A 1QLCA 1WIFA 5B6LA 2Z17A 1UEQA 1OZIA 3KDKA 1G9OA 4K75A 4Q6HA 2I6VA 1NF3C 4FGMA 1XZ9A 2AWUA 2MHOA 1L6OA 2AWXA 2KJKA 3PDZA 2KOHA 1N6FA 2QBWA 3O5NA 4R2ZA 2KPLA 1V62A 3ID2A 2CSJA 2JWEA 5G1DA 1K32A 1LCYA 1KWAA 3MH7A 3WKMA 3ID4A 2QT5A 1N6EA 2FE5A 5IL9A 2M0VA 3NCVA 3VQFA 1ZUBA 3K1RA 1GQ5A 2JXOA 3QGLA 4HOPB 4JOHA 2HGAA 3GSLA 2QKUA 2EDPA 2EJYA 4LMMA 2DC2A 1WFGA 4K72A 2Z9IA 3HPKA 2VSVA 4JOFA 1IU2A 2H2BA 2OGPA 4NMVA 4JOJA 4NMRA 2DLUA 2HE2A 2D92A 1WFVA 3RL7A 1TQ3A 2M0TA 3ID1A 3TSWA 4F8KA 3KHFA 1V5QA 2V90A 2JIKA 3O46A 1UJUA 5HJ1A 1R6JA 2QG1A 3KZEA 3BPUA 2DJTA 2Q3GA 4K76A 1WF8A 2KL1A 3SOEA 3TMHA 1X5QA 3AXAA 1P1DA 2KOMA 2I0LA 5F3XA 4UU6A 4E3BA 1X6DA 2EXGA 1X45A 3KDGA 4AMHA 4GHNA 5EZ0A 4KFVA 4GVDA 4E34A 4NNLA 2EGKA 4WYUA 5E21A 5H3JA 3HVQC 2M0ZA 2JREA 2H3MA 3DJAA 2DKRA 4JJ0A 3DIWA 3K50A 2H2CA 2KYLA 4Q2OA 2GEFA 2IWPA 1W9EA 3I1EA 2M10A 2IWOA 4YYXA 2VWRA 2LA8A 2F0AA 2LC7A 3GCNA 1N6DA 1WJLA 2D90A 2EEIA 5EYZA 2L4SA 1MC7A 1RY4A 1ZOKA 2YT8A 2PNTA 2Q9VA 4JL7A 4JJ3A 3PV2A 1QAVA 1X9ZA 1N7TA 1MFGA 1U38A 1UM1A 2DLSA 4JORA 2R3YA 3DJ1A 1I16A 1TP3A 3E17A 3CBYA 1BE9A 2O2TA 2HE4A 4UU5A 4O06A 1Q3PA 1V5LA 5HF1A 5B42A 2JSNA 4Z8JA 3RLEA 4NMSA 3NFLA 2G2LA 2VZ5A 2DMZA 3SHWA 2PDZA 4K6YA 4P0CA 3ZRTA 5HFBA 4NNMA 2LC6A 5D13A 3I4WA 2OCSA 2L4TA 1VAEA 2I04A 2KRGA 2M3MA 2IWNA 1KY9A 1QAUA 3GABA 2RCZA 2BYGA 2DM8A 3QO6A 2OQSA 4FLNA 1UF1A 3GDUA 1N99A 1UFXA 2YTWA 1W9QA 3PS4A 1X5RA 1OBZA 2D8IA 3DJ3A 5HFFA 1WHDA 1N7EA 2H3LA 3RL8A 2WL7A 2EHRA 3QDOA 2PZDA 3GCOA 1SOTA 2YUYA 4GVCA 4YDPA 5DTHA 4Q2PA 1UITA 3CH8A 1X5NA 3KZDA 2CS5A 5HEDA 1UJDA 1FCFA 3QJMA 2P3WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UEW A;  2KAW A;  2FN5 A;  5FB8 C;  2KBS A;  2YT7 A;  2DB5 A;  2JIL A;  1Z86 A;  2CSS A;  3NFK A;  3I18 A;  3QJN A;  1GM1 A;  2VPH A;  2R4H A;  3OTP A;  3DOR A;  3TSV A;  5A2P A;  1MFL A;  1UEP A;  1V6B A;  2EV8 A;  4NMP A;  3QE1 A;  2OS6 A;  2LUI A;  4OEO A;  4Q6S A;  1Y7N A;  2KA9 A;  4OEP A;  5HF4 A;  2OPG A;  1P1E A;  2RRM A;  2KPK A;  2ENO A;  4NMO A;  4Q2N A;  2EDZ A;  4JOP A;  1M5Z A;  3GGE A;  3L4F D;  2EEG A;  1QAV B;  5E1Y A;  3EGG C;  3GDS A;  2G5M B;  5I7Z A;  5GND A;  1RZX A;  5HEY A;  1FC7 A;  1GQ4 A;  1FC6 A;  1OBY A;  3STJ A;  3R0H A;  4L8N A;  2KJP A;  1VB7 A;  1FC9 A;  2EAQ A;  2PKT A;  1OBX A;  1RGR A;  4NXQ A;  1D5G A;  4JOG A;  2L97 A;  1Q7X A;  1WG6 A;  3FY5 A;  3R68 A;  4KFW A;  4NMQ A;  3CBZ A;  1VA8 A;  4NMT A;  3R69 A;  1UM7 A;  2KOJ A;  3PV5 A;  5HDY A;  4WYT A;  3WKL A;  3JXT A;  2W4F A;  1WF7 A;  1VCW A;  3MH4 A;  2YUB A;  3LNY A;  1U37 A;  1W9O A;  2I0I A;  3NGH A;  3EGH C;  2QKV A;  3ID3 A;  5HET A;  3CS0 A;  1X8S A;  1Z87 A;  4OAJ A;  2VRF A;  1WH1 A;  4Q2Q A;  5HFD A;  2EEJ A;  4Z33 A;  2KJD A;  2EDV A;  1N7F A;  3MH6 A;  4N6X A;  1NTE A;  5HFE A;  2JIN A;  2EGN A;  2I1N A;  2X7Z A;  2OMJ A;  4Q3H A;  3OU0 A;  3SHU A;  2AIN A;  3LNX A;  1KEF A;  2E7K A;  5G1E A;  4H11 A;  2MX6 A;  2V1W A;  5F67 A;  1IU0 A;  4NXP A;  5E6P B;  2AWW A;  1Y8T A;  2F5Y A;  3HPM A;  1RGW A;  3PV4 A;  4HOP A;  3B76 A;  2JOA A;  2VSP A;  4JOE A;  4NXR A;  2ZPL A;  3K82 A;  4JOK A;  3CBX A;  2KQF A;  4XHV A;  3GJ9 A;  2W7R A;  3SUZ A;  2EEH A;  5E11 A;  2UZC A;  4IC6 A;  2LOB A;  2OSG A;  5FHT A;  2K1Z A;  1WI2 A;  1TP5 A;  1WHA A;  2K20 A;  1V1T A;  3CC0 A;  1BFE A;  2EGO A;  3VQG A;  3QIK A;  2M0U A;  2I4S A;  1SOZ A;  1U39 A;  1IHJ A;  4EDJ A;  4RI0 A;  3TSZ A;  2FCF A;  2QKT A;  1U3B A;  4REY A;  3SFJ A;  2IWQ A;  1WI4 A;  4PQW A;  2FNE A;  1Q3O A;  5JXB A;  2KG2 A;  2KV8 A;  1UJV A;  2REY A;  2GZV A;  2PKU A;  1T2M A;  5HEB A;  3CYY A;  1TE0 A;  1VJ6 A;  2PA1 A;  5HFC A;  5GLJ A;  1YBO A;  4MPA A;  1B8Q A;  4P2A B;  1UEZ A;  4K78 A;  1PDR A;  2ZPM A;  1UHP A;  2OZF A;  3GDV A;  4E35 A;  1I92 A;  3PDV A;  2DAZ A;  5E22 A;  4G69 A;  1QLC A;  1WIF A;  5B6L A;  2Z17 A;  1UEQ A;  1OZI A;  1G9O A;  4K75 A;  4Q6H A;  2I6V A;  1NF3 C;  4FGM A;  1XZ9 A;  2AWU A;  2MHO A;  1L6O A;  2AWX A;  2KJK A;  3PDZ A;  2KOH A;  1N6F A;  2QBW A;  3O5N A;  4R2Z A;  2KPL A;  1V62 A;  3ID2 A;  2CSJ A;  2JWE A;  5G1D A;  1K32 A;  1LCY A;  1KWA A;  3MH7 A;  3WKM A;  3ID4 A;  2QT5 A;  1N6E A;  2FE5 A;  2M0V A;  3VQF A;  1ZUB A;  3K1R A;  1GQ5 A;  2JXO A;  3QGL A;  4HOP B;  4JOH A;  2HGA A;  3GSL A;  2QKU A;  2EDP A;  2EJY A;  4LMM A;  2DC2 A;  1WFG A;  4K72 A;  2Z9I A;  3HPK A;  2VSV A;  4JOF A;  1IU2 A;  2H2B A;  2OGP A;  4NMV A;  4JOJ A;  4NMR A;  2DLU A;  2HE2 A;  2D92 A;  1WFV A;  3RL7 A;  1TQ3 A;  2M0T A;  3ID1 A;  3TSW A;  4F8K A;  3KHF A;  1V5Q A;  2V90 A;  2JIK A;  3O46 A;  1UJU A;  5HJ1 A;  1R6J A;  2QG1 A;  3KZE A;  3BPU A;  2DJT A;  2Q3G A;  4K76 A;  1WF8 A;  2KL1 A;  3SOE A;  3TMH A;  1X5Q A;  3AXA A;  1P1D A;  2KOM A;  2I0L A;  5F3X A;  4UU6 A;  4E3B A;  1X6D A;  2EXG A;  1X45 A;  4AMH A;  4GHN A;  5EZ0 A;  4KFV A;  4GVD A;  4E34 A;  4NNL A;  2EGK A;  4WYU A;  5E21 A;  5H3J A;  3HVQ C;  2M0Z A;  2JRE A;  2H3M A;  3DJA A;  2DKR A;  3DIW A;  3K50 A;  2H2C A;  2KYL A;  4Q2O A;  2IWP A;  1W9E A;  3I1E A;  2M10 A;  2IWO A;  4YYX A;  2VWR A;  2LA8 A;  2F0A A;  2LC7 A;  3GCN A;  1N6D A;  1WJL A;  2D90 A;  2EEI A;  5EYZ A;  2L4S A;  1MC7 A;  1RY4 A;  1ZOK A;  2YT8 A;  2PNT A;  2Q9V A;  4JL7 A;  3PV2 A;  1QAV A;  1N7T A;  1MFG A;  1U38 A;  1UM1 A;  2DLS A;  4JOR A;  2R3Y A;  3DJ1 A;  1I16 A;  1TP3 A;  3E17 A;  3CBY A;  1BE9 A;  2O2T A;  2HE4 A;  4UU5 A;  4O06 A;  1Q3P A;  1V5L A;  5HF1 A;  4Z8J A;  3RLE A;  4NMS A;  3NFL A;  2G2L A;  2VZ5 A;  2DMZ A;  3SHW A;  2PDZ A;  4K6Y A;  4P0C A;  3ZRT A;  5HFB A;  4NNM A;  2LC6 A;  5D13 A;  3I4W A;  2OCS A;  2L4T A;  1VAE A;  2I04 A;  2KRG A;  2M3M A;  2IWN A;  1KY9 A;  1QAU A;  2RCZ A;  2BYG A;  2DM8 A;  3QO6 A;  2OQS A;  1UF1 A;  3GDU A;  1N99 A;  1UFX A;  2YTW A;  1W9Q A;  3PS4 A;  1X5R A;  1OBZ A;  2D8I A;  3DJ3 A;  5HFF A;  1WHD A;  1N7E A;  2H3L A;  3RL8 A;  2WL7 A;  2EHR A;  3QDO A;  2PZD A;  3GCO A;  1SOT A;  2YUY A;  4GVC A;  4YDP A;  5DTH A;  4Q2P A;  1UIT A;  3CH8 A;  1X5N A;  3KZD A;  2CS5 A;  5HED A;  1UJD A;  1FCF A;  3QJM A;  2P3W A; 
#chains in the Genus database with same CATH topology
 1UEW A;  2KAW A;  2FN5 A;  5FB8 C;  2KBS A;  2YT7 A;  2DB5 A;  2JIL A;  1Z86 A;  2CSS A;  3NFK A;  3I18 A;  3QJN A;  1GM1 A;  2VPH A;  2R4H A;  3OTP A;  3DOR A;  3TSV A;  5A2P A;  1MFL A;  1UEP A;  1V6B A;  2EV8 A;  4NMP A;  3QE1 A;  2OS6 A;  2LUI A;  4OEO A;  4Q6S A;  1Y7N A;  2KA9 A;  4OEP A;  5HF4 A;  2OPG A;  1P1E A;  2RRM A;  2KPK A;  2ENO A;  4NMO A;  4Q2N A;  2EDZ A;  4JOP A;  1M5Z A;  3GGE A;  3L4F D;  2EEG A;  1QAV B;  5E1Y A;  3EGG C;  3GDS A;  2G5M B;  5I7Z A;  5GND A;  1RZX A;  5HEY A;  1FC7 A;  1GQ4 A;  1FC6 A;  1OBY A;  3STJ A;  3R0H A;  4L8N A;  2KJP A;  1VB7 A;  1FC9 A;  2EAQ A;  2PKT A;  1OBX A;  1RGR A;  4NXQ A;  1D5G A;  4JOG A;  2L97 A;  1Q7X A;  1WG6 A;  3FY5 A;  3R68 A;  4KFW A;  4NMQ A;  3CBZ A;  1VA8 A;  4NMT A;  3R69 A;  1UM7 A;  2KOJ A;  3PV5 A;  5HDY A;  4WYT A;  3WKL A;  3JXT A;  2W4F A;  1WF7 A;  1VCW A;  3MH4 A;  2YUB A;  3LNY A;  1U37 A;  1W9O A;  2I0I A;  3NGH A;  3EGH C;  2QKV A;  3ID3 A;  5HET A;  3CS0 A;  1X8S A;  1Z87 A;  4OAJ A;  2VRF A;  1WH1 A;  4Q2Q A;  5HFD A;  5ILB A;  2EEJ A;  4Z33 A;  2KJD A;  2EDV A;  1N7F A;  3MH6 A;  4N6X A;  1NTE A;  5HFE A;  2JIN A;  2EGN A;  2I1N A;  2X7Z A;  2OMJ A;  4Q3H A;  3OU0 A;  3SHU A;  2AIN A;  3LNX A;  1KEF A;  2E7K A;  5G1E A;  4H11 A;  2MX6 A;  2V1W A;  5F67 A;  1IU0 A;  4NXP A;  5E6P B;  2AWW A;  1Y8T A;  2F5Y A;  3HPM A;  1RGW A;  3PV4 A;  4HOP A;  3B76 A;  2JOA A;  2VSP A;  4JOE A;  4NXR A;  2ZPL A;  3K82 A;  4JOK A;  3CBX A;  2KQF A;  4XHV A;  3GJ9 A;  2W7R A;  3SUZ A;  2EEH A;  5E11 A;  2UZC A;  4IC6 A;  2LOB A;  2OSG A;  5FHT A;  2K1Z A;  1WI2 A;  1TP5 A;  1WHA A;  2K20 A;  1V1T A;  3CC0 A;  1BFE A;  2EGO A;  3VQG A;  3QIK A;  2M0U A;  2I4S A;  1SOZ A;  1U39 A;  1IHJ A;  4EDJ A;  4RI0 A;  3TSZ A;  2FCF A;  2QKT A;  1U3B A;  4REY A;  3SFJ A;  2IWQ A;  1WI4 A;  4PQW A;  2FNE A;  1Q3O A;  5JXB A;  2KG2 A;  2KV8 A;  1UJV A;  2REY A;  2GZV A;  2PKU A;  1T2M A;  5HEB A;  3CYY A;  1TE0 A;  1VJ6 A;  2PA1 A;  5HFC A;  5GLJ A;  1YBO A;  4MPA A;  1B8Q A;  4P2A B;  1UEZ A;  4K78 A;  1PDR A;  2ZPM A;  1UHP A;  2OZF A;  3GDV A;  4E35 A;  1I92 A;  3PDV A;  2DAZ A;  5E22 A;  4G69 A;  1QLC A;  1WIF A;  5B6L A;  2Z17 A;  1UEQ A;  1OZI A;  3KDK A;  1G9O A;  4K75 A;  4Q6H A;  2I6V A;  1NF3 C;  4FGM A;  1XZ9 A;  2AWU A;  2MHO A;  1L6O A;  2AWX A;  2KJK A;  3PDZ A;  2KOH A;  1N6F A;  2QBW A;  3O5N A;  4R2Z A;  2KPL A;  1V62 A;  3ID2 A;  2CSJ A;  2JWE A;  5G1D A;  1K32 A;  1LCY A;  1KWA A;  3MH7 A;  3WKM A;  3ID4 A;  2QT5 A;  1N6E A;  2FE5 A;  5IL9 A;  2M0V A;  3NCV A;  3VQF A;  1ZUB A;  3K1R A;  1GQ5 A;  2JXO A;  3QGL A;  4HOP B;  4JOH A;  2HGA A;  3GSL A;  2QKU A;  2EDP A;  2EJY A;  4LMM A;  2DC2 A;  1WFG A;  4K72 A;  2Z9I A;  3HPK A;  2VSV A;  4JOF A;  1IU2 A;  2H2B A;  2OGP A;  4NMV A;  4JOJ A;  4NMR A;  2DLU A;  2HE2 A;  2D92 A;  1WFV A;  3RL7 A;  1TQ3 A;  2M0T A;  3ID1 A;  3TSW A;  4F8K A;  3KHF A;  1V5Q A;  2V90 A;  2JIK A;  3O46 A;  1UJU A;  5HJ1 A;  1R6J A;  2QG1 A;  3KZE A;  3BPU A;  2DJT A;  2Q3G A;  4K76 A;  1WF8 A;  2KL1 A;  3SOE A;  3TMH A;  1X5Q A;  3AXA A;  1P1D A;  2KOM A;  2I0L A;  5F3X A;  4UU6 A;  4E3B A;  1X6D A;  2EXG A;  1X45 A;  3KDG A;  4AMH A;  4GHN A;  5EZ0 A;  4KFV A;  4GVD A;  4E34 A;  4NNL A;  2EGK A;  4WYU A;  5E21 A;  5H3J A;  3HVQ C;  2M0Z A;  2JRE A;  2H3M A;  3DJA A;  2DKR A;  4JJ0 A;  3DIW A;  3K50 A;  2H2C A;  2KYL A;  4Q2O A;  2GEF A;  2IWP A;  1W9E A;  3I1E A;  2M10 A;  2IWO A;  4YYX A;  2VWR A;  2LA8 A;  2F0A A;  2LC7 A;  3GCN A;  1N6D A;  1WJL A;  2D90 A;  2EEI A;  5EYZ A;  2L4S A;  1MC7 A;  1RY4 A;  1ZOK A;  2YT8 A;  2PNT A;  2Q9V A;  4JL7 A;  4JJ3 A;  3PV2 A;  1QAV A;  1X9Z A;  1N7T A;  1MFG A;  1U38 A;  1UM1 A;  2DLS A;  4JOR A;  2R3Y A;  3DJ1 A;  1I16 A;  1TP3 A;  3E17 A;  3CBY A;  1BE9 A;  2O2T A;  2HE4 A;  4UU5 A;  4O06 A;  1Q3P A;  1V5L A;  5HF1 A;  5B42 A;  2JSN A;  4Z8J A;  3RLE A;  4NMS A;  3NFL A;  2G2L A;  2VZ5 A;  2DMZ A;  3SHW A;  2PDZ A;  4K6Y A;  4P0C A;  3ZRT A;  5HFB A;  4NNM A;  2LC6 A;  5D13 A;  3I4W A;  2OCS A;  2L4T A;  1VAE A;  2I04 A;  2KRG A;  2M3M A;  2IWN A;  1KY9 A;  1QAU A;  3GAB A;  2RCZ A;  2BYG A;  2DM8 A;  3QO6 A;  2OQS A;  4FLN A;  1UF1 A;  3GDU A;  1N99 A;  1UFX A;  2YTW A;  1W9Q A;  3PS4 A;  1X5R A;  1OBZ A;  2D8I A;  3DJ3 A;  5HFF A;  1WHD A;  1N7E A;  2H3L A;  3RL8 A;  2WL7 A;  2EHR A;  3QDO A;  2PZD A;  3GCO A;  1SOT A;  2YUY A;  4GVC A;  4YDP A;  5DTH A;  4Q2P A;  1UIT A;  3CH8 A;  1X5N A;  3KZD A;  2CS5 A;  5HED A;  1UJD A;  1FCF A;  3QJM A;  2P3W A; 
#chains in the Genus database with same CATH homology
 1UEW A;  2KAW A;  2FN5 A;  5FB8 C;  2KBS A;  2YT7 A;  2DB5 A;  2JIL A;  1Z86 A;  2CSS A;  3NFK A;  3I18 A;  3QJN A;  1GM1 A;  2VPH A;  2R4H A;  3OTP A;  3DOR A;  3TSV A;  5A2P A;  1MFL A;  1UEP A;  1V6B A;  2EV8 A;  4NMP A;  3QE1 A;  2OS6 A;  2LUI A;  4OEO A;  4Q6S A;  1Y7N A;  2KA9 A;  4OEP A;  5HF4 A;  2OPG A;  1P1E A;  2RRM A;  2KPK A;  2ENO A;  4NMO A;  4Q2N A;  2EDZ A;  4JOP A;  1M5Z A;  3GGE A;  3L4F D;  2EEG A;  1QAV B;  5E1Y A;  3EGG C;  3GDS A;  2G5M B;  5I7Z A;  5GND A;  1RZX A;  5HEY A;  1FC7 A;  1GQ4 A;  1FC6 A;  1OBY A;  3STJ A;  3R0H A;  4L8N A;  2KJP A;  1VB7 A;  1FC9 A;  2EAQ A;  2PKT A;  1OBX A;  1RGR A;  4NXQ A;  1D5G A;  4JOG A;  2L97 A;  1Q7X A;  1WG6 A;  3FY5 A;  3R68 A;  4KFW A;  4NMQ A;  3CBZ A;  1VA8 A;  4NMT A;  3R69 A;  1UM7 A;  2KOJ A;  3PV5 A;  5HDY A;  4WYT A;  3WKL A;  3JXT A;  2W4F A;  1WF7 A;  1VCW A;  3MH4 A;  2YUB A;  3LNY A;  1U37 A;  1W9O A;  2I0I A;  3NGH A;  3EGH C;  2QKV A;  3ID3 A;  5HET A;  3CS0 A;  1X8S A;  1Z87 A;  4OAJ A;  2VRF A;  1WH1 A;  4Q2Q A;  5HFD A;  5ILB A;  2EEJ A;  4Z33 A;  2KJD A;  2EDV A;  1N7F A;  3MH6 A;  4N6X A;  1NTE A;  5HFE A;  2JIN A;  2EGN A;  2I1N A;  2X7Z A;  2OMJ A;  4Q3H A;  3OU0 A;  3SHU A;  2AIN A;  3LNX A;  1KEF A;  2E7K A;  5G1E A;  4H11 A;  2MX6 A;  2V1W A;  5F67 A;  1IU0 A;  4NXP A;  5E6P B;  2AWW A;  1Y8T A;  2F5Y A;  3HPM A;  1RGW A;  3PV4 A;  4HOP A;  3B76 A;  2JOA A;  2VSP A;  4JOE A;  4NXR A;  2ZPL A;  3K82 A;  4JOK A;  3CBX A;  2KQF A;  4XHV A;  3GJ9 A;  2W7R A;  3SUZ A;  2EEH A;  5E11 A;  2UZC A;  4IC6 A;  2LOB A;  2OSG A;  5FHT A;  2K1Z A;  1WI2 A;  1TP5 A;  1WHA A;  2K20 A;  1V1T A;  3CC0 A;  1BFE A;  2EGO A;  3VQG A;  3QIK A;  2M0U A;  2I4S A;  1SOZ A;  1U39 A;  1IHJ A;  4EDJ A;  4RI0 A;  3TSZ A;  2FCF A;  2QKT A;  1U3B A;  4REY A;  3SFJ A;  2IWQ A;  1WI4 A;  4PQW A;  2FNE A;  1Q3O A;  5JXB A;  2KG2 A;  2KV8 A;  1UJV A;  2REY A;  2GZV A;  2PKU A;  1T2M A;  5HEB A;  3CYY A;  1TE0 A;  1VJ6 A;  2PA1 A;  5HFC A;  5GLJ A;  1YBO A;  4MPA A;  1B8Q A;  4P2A B;  1UEZ A;  4K78 A;  1PDR A;  2ZPM A;  1UHP A;  2OZF A;  3GDV A;  4E35 A;  1I92 A;  3PDV A;  2DAZ A;  5E22 A;  4G69 A;  1QLC A;  1WIF A;  5B6L A;  2Z17 A;  1UEQ A;  1OZI A;  3KDK A;  1G9O A;  4K75 A;  4Q6H A;  2I6V A;  1NF3 C;  4FGM A;  1XZ9 A;  2AWU A;  2MHO A;  1L6O A;  2AWX A;  2KJK A;  3PDZ A;  2KOH A;  1N6F A;  2QBW A;  3O5N A;  4R2Z A;  2KPL A;  1V62 A;  3ID2 A;  2CSJ A;  2JWE A;  5G1D A;  1K32 A;  1LCY A;  1KWA A;  3MH7 A;  3WKM A;  3ID4 A;  2QT5 A;  1N6E A;  2FE5 A;  5IL9 A;  2M0V A;  3NCV A;  3VQF A;  1ZUB A;  3K1R A;  1GQ5 A;  2JXO A;  3QGL A;  4HOP B;  4JOH A;  2HGA A;  3GSL A;  2QKU A;  2EDP A;  2EJY A;  4LMM A;  2DC2 A;  1WFG A;  4K72 A;  2Z9I A;  3HPK A;  2VSV A;  4JOF A;  1IU2 A;  2H2B A;  2OGP A;  4NMV A;  4JOJ A;  4NMR A;  2DLU A;  2HE2 A;  2D92 A;  1WFV A;  3RL7 A;  1TQ3 A;  2M0T A;  3ID1 A;  3TSW A;  4F8K A;  3KHF A;  1V5Q A;  2V90 A;  2JIK A;  3O46 A;  1UJU A;  5HJ1 A;  1R6J A;  2QG1 A;  3KZE A;  3BPU A;  2DJT A;  2Q3G A;  4K76 A;  1WF8 A;  2KL1 A;  3SOE A;  3TMH A;  1X5Q A;  3AXA A;  1P1D A;  2KOM A;  2I0L A;  5F3X A;  4UU6 A;  4E3B A;  1X6D A;  2EXG A;  1X45 A;  3KDG A;  4AMH A;  4GHN A;  5EZ0 A;  4KFV A;  4GVD A;  4E34 A;  4NNL A;  2EGK A;  4WYU A;  5E21 A;  5H3J A;  3HVQ C;  2M0Z A;  2JRE A;  2H3M A;  3DJA A;  2DKR A;  4JJ0 A;  3DIW A;  3K50 A;  2H2C A;  2KYL A;  4Q2O A;  2GEF A;  2IWP A;  1W9E A;  3I1E A;  2M10 A;  2IWO A;  4YYX A;  2VWR A;  2LA8 A;  2F0A A;  2LC7 A;  3GCN A;  1N6D A;  1WJL A;  2D90 A;  2EEI A;  5EYZ A;  2L4S A;  1MC7 A;  1RY4 A;  1ZOK A;  2YT8 A;  2PNT A;  2Q9V A;  4JL7 A;  4JJ3 A;  3PV2 A;  1QAV A;  1X9Z A;  1N7T A;  1MFG A;  1U38 A;  1UM1 A;  2DLS A;  4JOR A;  2R3Y A;  3DJ1 A;  1I16 A;  1TP3 A;  3E17 A;  3CBY A;  1BE9 A;  2O2T A;  2HE4 A;  4UU5 A;  4O06 A;  1Q3P A;  1V5L A;  5HF1 A;  5B42 A;  2JSN A;  4Z8J A;  3RLE A;  4NMS A;  3NFL A;  2G2L A;  2VZ5 A;  2DMZ A;  3SHW A;  2PDZ A;  4K6Y A;  4P0C A;  3ZRT A;  5HFB A;  4NNM A;  2LC6 A;  5D13 A;  3I4W A;  2OCS A;  2L4T A;  1VAE A;  2I04 A;  2KRG A;  2M3M A;  2IWN A;  1KY9 A;  1QAU A;  3GAB A;  2RCZ A;  2BYG A;  2DM8 A;  3QO6 A;  2OQS A;  4FLN A;  1UF1 A;  3GDU A;  1N99 A;  1UFX A;  2YTW A;  1W9Q A;  3PS4 A;  1X5R A;  1OBZ A;  2D8I A;  3DJ3 A;  5HFF A;  1WHD A;  1N7E A;  2H3L A;  3RL8 A;  2WL7 A;  2EHR A;  3QDO A;  2PZD A;  3GCO A;  1SOT A;  2YUY A;  4GVC A;  4YDP A;  5DTH A;  4Q2P A;  1UIT A;  3CH8 A;  1X5N A;  3KZD A;  2CS5 A;  5HED A;  1UJD A;  1FCF A;  3QJM A;  2P3W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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