4JOFA

Cftr associated ligand (cal) pdz domain bound to peptide l-ical36 (ansrlptsii)
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
87
structure length
87
Chain Sequence
GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Homo sapiens
molecule keywords Golgi-associated PDZ and coiled-coil motif-containing protei
total genus 22
structure length 87
sequence length 87
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4jofA00
2IWQA 5E22A 3PV2A 1KY9A 1UFXA 2OGPA 4Q6HA 1I16A 1Q3PA 1IU0A 3K82A 4HOPB 1UF1A 1Y8TA 2FCFA 3I4WA 4NMQA 1Z87A 5JXBA 1RGWA 2KL1A 2EEIA 3K50A 4Q2NA 2V90A 3WKMA 2LOBA 1BE9A 3CBYA 2L4SA 2VZ5A 3BPUA 2IWPA 5HFEA 4YYXA 1UITA 2HE4A 2PKUA 2EEGA 3GDUA 1X5NA 2KJPA 2X7ZA 2OSGA 4JOFA 1Q3OA 2AINA 2EAQA 5F67A 5HF1A 2PZDA 3I18A 3MH6A 4HOPA 3CH8A 3GCNA 1UJVA 3GDVA 1TP5A 1VA8A 3ID3A 4K6YA 1UJDA 2ZPMA 2EHRA 4O06A 3DORA 3MH4A 2YT7A 2PDZA 4L8NA 2CSSA 2OQSA 3AXAA 3EGGC 4OAJA 2YT8A 4NXRA 1N7EA 4JORA 3R69A 1GM1A 1XZ9A 2D8IA 4AMHA 2KPLA 3SHWA 1BFEA 1Q7XA 2M3MA 1L6OA 4K78A 4E34A 1N6EA 1WFGA 1W9QA 4NMSA 5E11A 3PS4A 2M0TA 2EDZA 2K1ZA 4IC6A 4KFVA 2JOAA 5HDYA 2H3MA 1SOZA 1IU2A 3EGHC 4JOGA 2KPKA 2PA1A 4OEOA 2VPHA 5EZ0A 2DLSA 5G1EA 2OPGA 5GLJA 2WL7A 5GNDA 1IHJA 1N7TA 3R0HA 5E6PB 4GVCA 4G69A 3ID2A 4Q2OA 3SUZA 2AWUA 2GZVA 2M10A 4UU5A 5G1DA 1R6JA 2KOHA 4NNMA 2EXGA 3NGHA 3QE1A 3K1RA 1MFGA 5EYZA 3NFLA 3SOEA 4JOKA 3CS0A 4R2ZA 2KRGA 4K72A 1VB7A 1M5ZA 3O5NA 2EJYA 1I92A 2DM8A 1U37A 1PDRA 4WYTA 2IWOA 3ID1A 1RGRA 4KFWA 5HEYA 2OZFA 3VQFA 2QKUA 1N7FA 2FE5A 1GQ4A 3OTPA 3NFKA 2I4SA 3TSZA 2YTWA 1VAEA 2RRMA 1WFVA 2VSPA 1W9EA 1Z86A 3VQGA 3GGEA 5HETA 2K20A 4Z33A 4NMOA 2DLUA 1U38A 2Z17A 1UEQA 4NMRA 1UM1A 1NF3C 2VWRA 4Q2QA 2M0VA 3SHUA 2BYGA 3PV4A 2I0LA 3GSLA 5B6LA 4NXPA 4JOPA 1Y7NA 4LMMA 1ZOKA 2H2BA 2IWNA 2MX6A 3I1EA 2DAZA 2AWXA 3CC0A 4Q3HA 4F8KA 2PKTA 3WKLA 2EDPA 1MC7A 2REYA 3QIKA 5HFCA 1WJLA 1UM7A 4EDJA 4JOEA 3LNXA 4XHVA 1OBYA 2F0AA 2QBWA 1X6DA 5E1YA 2F5YA 1P1DA 2QT5A 2Z9IA 3HVQC 4JL7A 1X5QA 5F3XA 3R68A 3FY5A 2KA9A 2D92A 2YUBA 3PDZA 1OBXA 2KJDA 2JINA 1D5GA 2JIKA 2JXOA 1WH1A 1WI2A 2EGNA 2JILA 2LUIA 3GCOA 1FCFA 2H2CA 4PQWA 3CBXA 3HPKA 2W4FA 3KZDA 2MHOA 2EDVA 4GVDA 4K75A 1X8SA 1U39A 2I04A 2KQFA 3B76A 1WI4A 1T2MA 3RL8A 1TE0A 2W7RA 1UJUA 1V5LA 3PDVA 5FHTA 1WIFA 1WHAA 4P2AB 2DC2A 2KJKA 3TSWA 4YDPA 2L97A 5HEBA 2KOJA 3QO6A 2R3YA 1TQ3A 4RI0A 2HGAA 2Q9VA 2KOMA 2FN5A 5HFFA 1V5QA 2D90A 5HF4A 3CBZA 2UZCA 1LCYA 1KEFA 1QAVB 3E17A 2M0ZA 2JREA 1QLCA 2QKTA 1V62A 2LC6A 3QJNA 2DKRA 1UEWA 4JOHA 1KWAA 3OU0A 2Q3GA 3QGLA 4WYUA 4MPAA 1P1EA 3SFJA 5HJ1A 3ID4A 2AWWA 2L4TA 2FNEA 2ENOA 1U3BA 3HPMA 2VSVA 4P0CA 5HFDA 2E7KA 3QDOA 2KG2A 2I1NA 3O46A 1NTEA 1MFLA 2YUYA 3CYYA 4K76A 5FB8C 2QKVA 4E35A 2CS5A 4UU6A 2OS6A 1QAVA 5HEDA 4NMPA 2LC7A 4JOJA 1FC7A 3RL7A 2QG1A 2RCZA 1FC9A 1VJ6A 3DIWA 2VRFA 2G2LA 1N99A 3DJAA 3PV5A 3TMHA 5E21A 2P3WA 1GQ5A 4Z8JA 1QAUA 1OZIA 3KHFA 3MH7A 1WHDA 3JXTA 2V1WA 1RZXA 3GJ9A 5HFBA 2ZPLA 1K32A 2G5MB 2H3LA 1OBZA 2CSJA 1YBOA 4FGMA 4NNLA 3RLEA 2EEJA 4N6XA 1UHPA 4NMVA 3L4FD 1V1TA 4Q6SA 3QJMA 2KYLA 4Q2PA 4REYA 2HE2A 4OEPA 2M0UA 3KZEA 1N6FA 1X45A 2EGKA 2KBSA 2OMJA 1TP3A 4NMTA 1WF8A 1UEPA 1W9OA 3GDSA 4GHNA 1ZUBA 1WF7A 3DJ3A 3TSVA 1G9OA 4H11A 1V6BA 1X5RA 1VCWA 2DJTA 1SOTA 1B8QA 2LA8A 2I6VA 2EV8A 1N6DA 2DMZA 2O2TA 1FC6A 2EEHA 3LNYA 2DB5A 2KAWA 3ZRTA 2JWEA 5I7ZA 2R4HA 1RY4A 2EGOA 2OCSA 3STJA 2PNTA 5DTHA 4E3BA 2I0IA 3DJ1A 5D13A 1UEZA 1WG6A 5A2PA 4NXQA 2KV8A 5H3JA
chains in the Genus database with same CATH superfamily
2IWQA 5E22A 3PV2A 1KY9A 1UFXA 2OGPA 4Q6HA 1I16A 1Q3PA 1IU0A 3K82A 4HOPB 1UF1A 1Y8TA 2FCFA 3I4WA 4NMQA 1Z87A 5JXBA 1RGWA 2KL1A 2EEIA 3K50A 4Q2NA 2V90A 3WKMA 2LOBA 1BE9A 3CBYA 2L4SA 2VZ5A 3BPUA 2IWPA 5HFEA 4YYXA 1UITA 2HE4A 2PKUA 2EEGA 3GDUA 1X5NA 2KJPA 2X7ZA 2OSGA 4JOFA 1Q3OA 2AINA 2EAQA 5F67A 5HF1A 2PZDA 3I18A 3MH6A 4HOPA 3CH8A 3GCNA 1UJVA 3GDVA 1X9ZA 1TP5A 1VA8A 3ID3A 4K6YA 1UJDA 2ZPMA 2EHRA 4O06A 3DORA 3MH4A 2YT7A 2PDZA 4L8NA 2CSSA 2OQSA 3AXAA 3EGGC 4OAJA 2YT8A 4NXRA 1N7EA 4JORA 3R69A 1GM1A 1XZ9A 2D8IA 4AMHA 2KPLA 3SHWA 1BFEA 1Q7XA 2M3MA 1L6OA 4K78A 4E34A 1N6EA 1WFGA 1W9QA 4NMSA 5E11A 3PS4A 2M0TA 2EDZA 2K1ZA 4IC6A 4KFVA 2JOAA 5HDYA 2H3MA 1SOZA 1IU2A 3EGHC 4JJ0A 4JOGA 2KPKA 2PA1A 4OEOA 2VPHA 4JJ3A 5EZ0A 2DLSA 5G1EA 2OPGA 5GLJA 2WL7A 5IL9A 5GNDA 1IHJA 1N7TA 3R0HA 5E6PB 4GVCA 4G69A 3ID2A 4Q2OA 3SUZA 2AWUA 2GZVA 2M10A 4UU5A 5G1DA 1R6JA 2KOHA 4NNMA 2EXGA 3NGHA 3QE1A 3K1RA 1MFGA 5EYZA 3NFLA 3SOEA 4JOKA 3CS0A 4R2ZA 2KRGA 4K72A 1VB7A 1M5ZA 3O5NA 2EJYA 1I92A 2DM8A 1U37A 1PDRA 4WYTA 2IWOA 3ID1A 1RGRA 4KFWA 5HEYA 2OZFA 3VQFA 2QKUA 1N7FA 2FE5A 1GQ4A 3OTPA 3NFKA 2I4SA 3TSZA 2YTWA 1VAEA 2RRMA 1WFVA 2VSPA 1W9EA 1Z86A 3VQGA 3GGEA 5HETA 2K20A 4Z33A 4NMOA 2DLUA 1U38A 2Z17A 1UEQA 2GEFA 4NMRA 1UM1A 1NF3C 2VWRA 4Q2QA 2M0VA 3SHUA 2BYGA 3PV4A 2I0LA 3GSLA 5B6LA 4NXPA 4JOPA 1Y7NA 4LMMA 1ZOKA 2H2BA 2IWNA 2MX6A 3I1EA 2DAZA 2AWXA 3CC0A 4Q3HA 4F8KA 2PKTA 3WKLA 2EDPA 1MC7A 2REYA 3QIKA 5HFCA 1WJLA 1UM7A 4EDJA 4JOEA 3LNXA 4XHVA 1OBYA 2F0AA 2QBWA 1X6DA 5E1YA 2F5YA 1P1DA 2QT5A 2Z9IA 3HVQC 4JL7A 1X5QA 5F3XA 3R68A 3FY5A 2KA9A 2D92A 2YUBA 3PDZA 1OBXA 2KJDA 2JINA 1D5GA 2JIKA 2JXOA 1WH1A 1WI2A 2EGNA 2JILA 2LUIA 3GCOA 1FCFA 2H2CA 4PQWA 3CBXA 3HPKA 2JSNA 2W4FA 3KZDA 2MHOA 2EDVA 4GVDA 4K75A 1X8SA 1U39A 2I04A 2KQFA 3B76A 1WI4A 1T2MA 3RL8A 1TE0A 2W7RA 1UJUA 3GABA 1V5LA 3PDVA 5FHTA 1WIFA 1WHAA 4P2AB 2DC2A 2KJKA 3TSWA 4YDPA 2L97A 5HEBA 2KOJA 3QO6A 2R3YA 1TQ3A 4RI0A 2HGAA 2Q9VA 2KOMA 2FN5A 5HFFA 1V5QA 2D90A 5HF4A 3CBZA 2UZCA 1LCYA 1KEFA 1QAVB 3E17A 2M0ZA 2JREA 1QLCA 2QKTA 1V62A 2LC6A 3QJNA 2DKRA 1UEWA 4JOHA 1KWAA 3OU0A 2Q3GA 3QGLA 4WYUA 4MPAA 1P1EA 3SFJA 5HJ1A 3ID4A 2AWWA 2L4TA 2FNEA 2ENOA 1U3BA 3HPMA 2VSVA 4P0CA 5HFDA 2E7KA 3QDOA 2KG2A 2I1NA 3O46A 1NTEA 1MFLA 2YUYA 3CYYA 4K76A 5FB8C 2QKVA 4E35A 3KDKA 2CS5A 4UU6A 2OS6A 1QAVA 5HEDA 4NMPA 2LC7A 4JOJA 1FC7A 3RL7A 2QG1A 2RCZA 1FC9A 1VJ6A 3DIWA 2VRFA 2G2LA 1N99A 3DJAA 3PV5A 3TMHA 5E21A 2P3WA 1GQ5A 4Z8JA 1QAUA 1OZIA 3KHFA 3MH7A 1WHDA 3JXTA 2V1WA 1RZXA 3GJ9A 5HFBA 2ZPLA 1K32A 2G5MB 2H3LA 1OBZA 2CSJA 1YBOA 4FGMA 4NNLA 3RLEA 5B42A 2EEJA 4N6XA 1UHPA 4NMVA 3L4FD 1V1TA 3NCVA 4Q6SA 3QJMA 2KYLA 4Q2PA 4REYA 2HE2A 4OEPA 2M0UA 3KZEA 1N6FA 1X45A 2EGKA 2KBSA 2OMJA 1TP3A 4NMTA 1WF8A 1UEPA 1W9OA 3GDSA 5ILBA 4GHNA 1ZUBA 1WF7A 3DJ3A 3TSVA 1G9OA 4H11A 1V6BA 1X5RA 1VCWA 2DJTA 1SOTA 1B8QA 2LA8A 2I6VA 4FLNA 2EV8A 1N6DA 2DMZA 2O2TA 1FC6A 2EEHA 3LNYA 2DB5A 2KAWA 3ZRTA 2JWEA 5I7ZA 2R4HA 1RY4A 2EGOA 2OCSA 3STJA 2PNTA 5DTHA 4E3BA 2I0IA 3DJ1A 5D13A 1UEZA 1WG6A 5A2PA 4NXQA 3KDGA 2KV8A 5H3JA
chains in the Genus database with same CATH topology
2IWQA 5E22A 3PV2A 1KY9A 1UFXA 2OGPA 4Q6HA 1I16A 1Q3PA 1IU0A 3K82A 4HOPB 1UF1A 1Y8TA 2FCFA 3I4WA 4NMQA 1Z87A 5JXBA 1RGWA 2KL1A 2EEIA 3K50A 4Q2NA 2V90A 3WKMA 2LOBA 1BE9A 3CBYA 2L4SA 2VZ5A 3BPUA 2IWPA 5HFEA 4YYXA 1UITA 2HE4A 2PKUA 2EEGA 3GDUA 1X5NA 2KJPA 2X7ZA 2OSGA 4JOFA 1Q3OA 2AINA 2EAQA 5F67A 5HF1A 2PZDA 3I18A 3MH6A 4HOPA 3CH8A 3GCNA 1UJVA 3GDVA 1X9ZA 1TP5A 1VA8A 3ID3A 4K6YA 1UJDA 2ZPMA 2EHRA 4O06A 3DORA 3MH4A 2YT7A 2PDZA 4L8NA 2CSSA 2OQSA 3AXAA 3EGGC 4OAJA 2YT8A 4NXRA 1N7EA 4JORA 3R69A 1GM1A 1XZ9A 2D8IA 4AMHA 2KPLA 3SHWA 1BFEA 1Q7XA 2M3MA 1L6OA 4K78A 4E34A 1N6EA 1WFGA 1W9QA 4NMSA 5E11A 3PS4A 2M0TA 2EDZA 2K1ZA 4IC6A 4KFVA 2JOAA 5HDYA 2H3MA 1SOZA 1IU2A 3EGHC 4JJ0A 4JOGA 2KPKA 2PA1A 4OEOA 2VPHA 4JJ3A 5EZ0A 2DLSA 5G1EA 2OPGA 5GLJA 2WL7A 5IL9A 5GNDA 1IHJA 1N7TA 3R0HA 5E6PB 4GVCA 4G69A 3ID2A 4Q2OA 3SUZA 2AWUA 2GZVA 2M10A 4UU5A 5G1DA 1R6JA 2KOHA 4NNMA 2EXGA 3NGHA 3QE1A 3K1RA 1MFGA 5EYZA 3NFLA 3SOEA 4JOKA 3CS0A 4R2ZA 2KRGA 4K72A 1VB7A 1M5ZA 3O5NA 2EJYA 1I92A 2DM8A 1U37A 1PDRA 4WYTA 2IWOA 3ID1A 1RGRA 4KFWA 5HEYA 2OZFA 3VQFA 2QKUA 1N7FA 2FE5A 1GQ4A 3OTPA 3NFKA 2I4SA 3TSZA 2YTWA 1VAEA 2RRMA 1WFVA 2VSPA 1W9EA 1Z86A 3VQGA 3GGEA 5HETA 2K20A 4Z33A 4NMOA 2DLUA 1U38A 2Z17A 1UEQA 2GEFA 4NMRA 1UM1A 1NF3C 2VWRA 4Q2QA 2M0VA 3SHUA 2BYGA 3PV4A 2I0LA 3GSLA 5B6LA 4NXPA 4JOPA 1Y7NA 4LMMA 1ZOKA 2H2BA 2IWNA 2MX6A 3I1EA 2DAZA 2AWXA 3CC0A 4Q3HA 4F8KA 2PKTA 3WKLA 2EDPA 1MC7A 2REYA 3QIKA 5HFCA 1WJLA 1UM7A 4EDJA 4JOEA 3LNXA 4XHVA 1OBYA 2F0AA 2QBWA 1X6DA 5E1YA 2F5YA 1P1DA 2QT5A 2Z9IA 3HVQC 4JL7A 1X5QA 5F3XA 3R68A 3FY5A 2KA9A 2D92A 2YUBA 3PDZA 1OBXA 2KJDA 2JINA 1D5GA 2JIKA 2JXOA 1WH1A 1WI2A 2EGNA 2JILA 2LUIA 3GCOA 1FCFA 2H2CA 4PQWA 3CBXA 3HPKA 2JSNA 2W4FA 3KZDA 2MHOA 2EDVA 4GVDA 4K75A 1X8SA 1U39A 2I04A 2KQFA 3B76A 1WI4A 1T2MA 3RL8A 1TE0A 2W7RA 1UJUA 3GABA 1V5LA 3PDVA 5FHTA 1WIFA 1WHAA 4P2AB 2DC2A 2KJKA 3TSWA 4YDPA 2L97A 5HEBA 2KOJA 3QO6A 2R3YA 1TQ3A 4RI0A 2HGAA 2Q9VA 2KOMA 2FN5A 5HFFA 1V5QA 2D90A 5HF4A 3CBZA 2UZCA 1LCYA 1KEFA 1QAVB 3E17A 2M0ZA 2JREA 1QLCA 2QKTA 1V62A 2LC6A 3QJNA 2DKRA 1UEWA 4JOHA 1KWAA 3OU0A 2Q3GA 3QGLA 4WYUA 4MPAA 1P1EA 3SFJA 5HJ1A 3ID4A 2AWWA 2L4TA 2FNEA 2ENOA 1U3BA 3HPMA 2VSVA 4P0CA 5HFDA 2E7KA 3QDOA 2KG2A 2I1NA 3O46A 1NTEA 1MFLA 2YUYA 3CYYA 4K76A 5FB8C 2QKVA 4E35A 3KDKA 2CS5A 4UU6A 2OS6A 1QAVA 5HEDA 4NMPA 2LC7A 4JOJA 1FC7A 3RL7A 2QG1A 2RCZA 1FC9A 1VJ6A 3DIWA 2VRFA 2G2LA 1N99A 3DJAA 3PV5A 3TMHA 5E21A 2P3WA 1GQ5A 4Z8JA 1QAUA 1OZIA 3KHFA 3MH7A 1WHDA 3JXTA 2V1WA 1RZXA 3GJ9A 5HFBA 2ZPLA 1K32A 2G5MB 2H3LA 1OBZA 2CSJA 1YBOA 4FGMA 4NNLA 3RLEA 5B42A 2EEJA 4N6XA 1UHPA 4NMVA 3L4FD 1V1TA 3NCVA 4Q6SA 3QJMA 2KYLA 4Q2PA 4REYA 2HE2A 4OEPA 2M0UA 3KZEA 1N6FA 1X45A 2EGKA 2KBSA 2OMJA 1TP3A 4NMTA 1WF8A 1UEPA 1W9OA 3GDSA 5ILBA 4GHNA 1ZUBA 1WF7A 3DJ3A 3TSVA 1G9OA 4H11A 1V6BA 1X5RA 1VCWA 2DJTA 1SOTA 1B8QA 2LA8A 2I6VA 4FLNA 2EV8A 1N6DA 2DMZA 2O2TA 1FC6A 2EEHA 3LNYA 2DB5A 2KAWA 3ZRTA 2JWEA 5I7ZA 2R4HA 1RY4A 2EGOA 2OCSA 3STJA 2PNTA 5DTHA 4E3BA 2I0IA 3DJ1A 5D13A 1UEZA 1WG6A 5A2PA 4NXQA 3KDGA 2KV8A 5H3JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IWQ A;  5E22 A;  3PV2 A;  1KY9 A;  1UFX A;  2OGP A;  4Q6H A;  1I16 A;  1Q3P A;  1IU0 A;  3K82 A;  4HOP B;  1UF1 A;  1Y8T A;  2FCF A;  3I4W A;  4NMQ A;  1Z87 A;  5JXB A;  1RGW A;  2KL1 A;  2EEI A;  3K50 A;  4Q2N A;  2V90 A;  3WKM A;  2LOB A;  1BE9 A;  3CBY A;  2L4S A;  2VZ5 A;  3BPU A;  2IWP A;  5HFE A;  4YYX A;  1UIT A;  2HE4 A;  2PKU A;  2EEG A;  3GDU A;  1X5N A;  2KJP A;  2X7Z A;  2OSG A;  4JOF A;  1Q3O A;  2AIN A;  2EAQ A;  5F67 A;  5HF1 A;  2PZD A;  3I18 A;  3MH6 A;  4HOP A;  3CH8 A;  3GCN A;  1UJV A;  3GDV A;  1TP5 A;  1VA8 A;  3ID3 A;  4K6Y A;  1UJD A;  2ZPM A;  2EHR A;  4O06 A;  3DOR A;  3MH4 A;  2YT7 A;  2PDZ A;  4L8N A;  2CSS A;  2OQS A;  3AXA A;  3EGG C;  4OAJ A;  2YT8 A;  4NXR A;  1N7E A;  4JOR A;  3R69 A;  1GM1 A;  1XZ9 A;  2D8I A;  4AMH A;  2KPL A;  3SHW A;  1BFE A;  1Q7X A;  2M3M A;  1L6O A;  4K78 A;  4E34 A;  1N6E A;  1WFG A;  1W9Q A;  4NMS A;  5E11 A;  3PS4 A;  2M0T A;  2EDZ A;  2K1Z A;  4IC6 A;  4KFV A;  2JOA A;  5HDY A;  2H3M A;  1SOZ A;  1IU2 A;  3EGH C;  4JOG A;  2KPK A;  2PA1 A;  4OEO A;  2VPH A;  5EZ0 A;  2DLS A;  5G1E A;  2OPG A;  5GLJ A;  2WL7 A;  5GND A;  1IHJ A;  1N7T A;  3R0H A;  5E6P B;  4GVC A;  4G69 A;  3ID2 A;  4Q2O A;  3SUZ A;  2AWU A;  2GZV A;  2M10 A;  4UU5 A;  5G1D A;  1R6J A;  2KOH A;  4NNM A;  2EXG A;  3NGH A;  3QE1 A;  3K1R A;  1MFG A;  5EYZ A;  3NFL A;  3SOE A;  4JOK A;  3CS0 A;  4R2Z A;  2KRG A;  4K72 A;  1VB7 A;  1M5Z A;  3O5N A;  2EJY A;  1I92 A;  2DM8 A;  1U37 A;  1PDR A;  4WYT A;  2IWO A;  3ID1 A;  1RGR A;  4KFW A;  5HEY A;  2OZF A;  3VQF A;  2QKU A;  1N7F A;  2FE5 A;  1GQ4 A;  3OTP A;  3NFK A;  2I4S A;  3TSZ A;  2YTW A;  1VAE A;  2RRM A;  1WFV A;  2VSP A;  1W9E A;  1Z86 A;  3VQG A;  3GGE A;  5HET A;  2K20 A;  4Z33 A;  4NMO A;  2DLU A;  1U38 A;  2Z17 A;  1UEQ A;  4NMR A;  1UM1 A;  1NF3 C;  2VWR A;  4Q2Q A;  2M0V A;  3SHU A;  2BYG A;  3PV4 A;  2I0L A;  3GSL A;  5B6L A;  4NXP A;  4JOP A;  1Y7N A;  4LMM A;  1ZOK A;  2H2B A;  2IWN A;  2MX6 A;  3I1E A;  2DAZ A;  2AWX A;  3CC0 A;  4Q3H A;  4F8K A;  2PKT A;  3WKL A;  2EDP A;  1MC7 A;  2REY A;  3QIK A;  5HFC A;  1WJL A;  1UM7 A;  4EDJ A;  4JOE A;  3LNX A;  4XHV A;  1OBY A;  2F0A A;  2QBW A;  1X6D A;  5E1Y A;  2F5Y A;  1P1D A;  2QT5 A;  2Z9I A;  3HVQ C;  4JL7 A;  1X5Q A;  5F3X A;  3R68 A;  3FY5 A;  2KA9 A;  2D92 A;  2YUB A;  3PDZ A;  1OBX A;  2KJD A;  2JIN A;  1D5G A;  2JIK A;  2JXO A;  1WH1 A;  1WI2 A;  2EGN A;  2JIL A;  2LUI A;  3GCO A;  1FCF A;  2H2C A;  4PQW A;  3CBX A;  3HPK A;  2W4F A;  3KZD A;  2MHO A;  2EDV A;  4GVD A;  4K75 A;  1X8S A;  1U39 A;  2I04 A;  2KQF A;  3B76 A;  1WI4 A;  1T2M A;  3RL8 A;  1TE0 A;  2W7R A;  1UJU A;  1V5L A;  3PDV A;  5FHT A;  1WIF A;  1WHA A;  4P2A B;  2DC2 A;  2KJK A;  3TSW A;  4YDP A;  2L97 A;  5HEB A;  2KOJ A;  3QO6 A;  2R3Y A;  1TQ3 A;  4RI0 A;  2HGA A;  2Q9V A;  2KOM A;  2FN5 A;  5HFF A;  1V5Q A;  2D90 A;  5HF4 A;  3CBZ A;  2UZC A;  1LCY A;  1KEF A;  1QAV B;  3E17 A;  2M0Z A;  2JRE A;  1QLC A;  2QKT A;  1V62 A;  2LC6 A;  3QJN A;  2DKR A;  1UEW A;  4JOH A;  1KWA A;  3OU0 A;  2Q3G A;  3QGL A;  4WYU A;  4MPA A;  1P1E A;  3SFJ A;  5HJ1 A;  3ID4 A;  2AWW A;  2L4T A;  2FNE A;  2ENO A;  1U3B A;  3HPM A;  2VSV A;  4P0C A;  5HFD A;  2E7K A;  3QDO A;  2KG2 A;  2I1N A;  3O46 A;  1NTE A;  1MFL A;  2YUY A;  3CYY A;  4K76 A;  5FB8 C;  2QKV A;  4E35 A;  2CS5 A;  4UU6 A;  2OS6 A;  1QAV A;  5HED A;  4NMP A;  2LC7 A;  4JOJ A;  1FC7 A;  3RL7 A;  2QG1 A;  2RCZ A;  1FC9 A;  1VJ6 A;  3DIW A;  2VRF A;  2G2L A;  1N99 A;  3DJA A;  3PV5 A;  3TMH A;  5E21 A;  2P3W A;  1GQ5 A;  4Z8J A;  1QAU A;  1OZI A;  3KHF A;  3MH7 A;  1WHD A;  3JXT A;  2V1W A;  1RZX A;  3GJ9 A;  5HFB A;  2ZPL A;  1K32 A;  2G5M B;  2H3L A;  1OBZ A;  2CSJ A;  1YBO A;  4FGM A;  4NNL A;  3RLE A;  2EEJ A;  4N6X A;  1UHP A;  4NMV A;  3L4F D;  1V1T A;  4Q6S A;  3QJM A;  2KYL A;  4Q2P A;  4REY A;  2HE2 A;  4OEP A;  2M0U A;  3KZE A;  1N6F A;  1X45 A;  2EGK A;  2KBS A;  2OMJ A;  1TP3 A;  4NMT A;  1WF8 A;  1UEP A;  1W9O A;  3GDS A;  4GHN A;  1ZUB A;  1WF7 A;  3DJ3 A;  3TSV A;  1G9O A;  4H11 A;  1V6B A;  1X5R A;  1VCW A;  2DJT A;  1SOT A;  1B8Q A;  2LA8 A;  2I6V A;  2EV8 A;  1N6D A;  2DMZ A;  2O2T A;  1FC6 A;  2EEH A;  3LNY A;  2DB5 A;  2KAW A;  3ZRT A;  2JWE A;  5I7Z A;  2R4H A;  1RY4 A;  2EGO A;  2OCS A;  3STJ A;  2PNT A;  5DTH A;  4E3B A;  2I0I A;  3DJ1 A;  5D13 A;  1UEZ A;  1WG6 A;  5A2P A;  4NXQ A;  2KV8 A;  5H3J A; 
#chains in the Genus database with same CATH topology
 2IWQ A;  5E22 A;  3PV2 A;  1KY9 A;  1UFX A;  2OGP A;  4Q6H A;  1I16 A;  1Q3P A;  1IU0 A;  3K82 A;  4HOP B;  1UF1 A;  1Y8T A;  2FCF A;  3I4W A;  4NMQ A;  1Z87 A;  5JXB A;  1RGW A;  2KL1 A;  2EEI A;  3K50 A;  4Q2N A;  2V90 A;  3WKM A;  2LOB A;  1BE9 A;  3CBY A;  2L4S A;  2VZ5 A;  3BPU A;  2IWP A;  5HFE A;  4YYX A;  1UIT A;  2HE4 A;  2PKU A;  2EEG A;  3GDU A;  1X5N A;  2KJP A;  2X7Z A;  2OSG A;  4JOF A;  1Q3O A;  2AIN A;  2EAQ A;  5F67 A;  5HF1 A;  2PZD A;  3I18 A;  3MH6 A;  4HOP A;  3CH8 A;  3GCN A;  1UJV A;  3GDV A;  1X9Z A;  1TP5 A;  1VA8 A;  3ID3 A;  4K6Y A;  1UJD A;  2ZPM A;  2EHR A;  4O06 A;  3DOR A;  3MH4 A;  2YT7 A;  2PDZ A;  4L8N A;  2CSS A;  2OQS A;  3AXA A;  3EGG C;  4OAJ A;  2YT8 A;  4NXR A;  1N7E A;  4JOR A;  3R69 A;  1GM1 A;  1XZ9 A;  2D8I A;  4AMH A;  2KPL A;  3SHW A;  1BFE A;  1Q7X A;  2M3M A;  1L6O A;  4K78 A;  4E34 A;  1N6E A;  1WFG A;  1W9Q A;  4NMS A;  5E11 A;  3PS4 A;  2M0T A;  2EDZ A;  2K1Z A;  4IC6 A;  4KFV A;  2JOA A;  5HDY A;  2H3M A;  1SOZ A;  1IU2 A;  3EGH C;  4JJ0 A;  4JOG A;  2KPK A;  2PA1 A;  4OEO A;  2VPH A;  4JJ3 A;  5EZ0 A;  2DLS A;  5G1E A;  2OPG A;  5GLJ A;  2WL7 A;  5IL9 A;  5GND A;  1IHJ A;  1N7T A;  3R0H A;  5E6P B;  4GVC A;  4G69 A;  3ID2 A;  4Q2O A;  3SUZ A;  2AWU A;  2GZV A;  2M10 A;  4UU5 A;  5G1D A;  1R6J A;  2KOH A;  4NNM A;  2EXG A;  3NGH A;  3QE1 A;  3K1R A;  1MFG A;  5EYZ A;  3NFL A;  3SOE A;  4JOK A;  3CS0 A;  4R2Z A;  2KRG A;  4K72 A;  1VB7 A;  1M5Z A;  3O5N A;  2EJY A;  1I92 A;  2DM8 A;  1U37 A;  1PDR A;  4WYT A;  2IWO A;  3ID1 A;  1RGR A;  4KFW A;  5HEY A;  2OZF A;  3VQF A;  2QKU A;  1N7F A;  2FE5 A;  1GQ4 A;  3OTP A;  3NFK A;  2I4S A;  3TSZ A;  2YTW A;  1VAE A;  2RRM A;  1WFV A;  2VSP A;  1W9E A;  1Z86 A;  3VQG A;  3GGE A;  5HET A;  2K20 A;  4Z33 A;  4NMO A;  2DLU A;  1U38 A;  2Z17 A;  1UEQ A;  2GEF A;  4NMR A;  1UM1 A;  1NF3 C;  2VWR A;  4Q2Q A;  2M0V A;  3SHU A;  2BYG A;  3PV4 A;  2I0L A;  3GSL A;  5B6L A;  4NXP A;  4JOP A;  1Y7N A;  4LMM A;  1ZOK A;  2H2B A;  2IWN A;  2MX6 A;  3I1E A;  2DAZ A;  2AWX A;  3CC0 A;  4Q3H A;  4F8K A;  2PKT A;  3WKL A;  2EDP A;  1MC7 A;  2REY A;  3QIK A;  5HFC A;  1WJL A;  1UM7 A;  4EDJ A;  4JOE A;  3LNX A;  4XHV A;  1OBY A;  2F0A A;  2QBW A;  1X6D A;  5E1Y A;  2F5Y A;  1P1D A;  2QT5 A;  2Z9I A;  3HVQ C;  4JL7 A;  1X5Q A;  5F3X A;  3R68 A;  3FY5 A;  2KA9 A;  2D92 A;  2YUB A;  3PDZ A;  1OBX A;  2KJD A;  2JIN A;  1D5G A;  2JIK A;  2JXO A;  1WH1 A;  1WI2 A;  2EGN A;  2JIL A;  2LUI A;  3GCO A;  1FCF A;  2H2C A;  4PQW A;  3CBX A;  3HPK A;  2JSN A;  2W4F A;  3KZD A;  2MHO A;  2EDV A;  4GVD A;  4K75 A;  1X8S A;  1U39 A;  2I04 A;  2KQF A;  3B76 A;  1WI4 A;  1T2M A;  3RL8 A;  1TE0 A;  2W7R A;  1UJU A;  3GAB A;  1V5L A;  3PDV A;  5FHT A;  1WIF A;  1WHA A;  4P2A B;  2DC2 A;  2KJK A;  3TSW A;  4YDP A;  2L97 A;  5HEB A;  2KOJ A;  3QO6 A;  2R3Y A;  1TQ3 A;  4RI0 A;  2HGA A;  2Q9V A;  2KOM A;  2FN5 A;  5HFF A;  1V5Q A;  2D90 A;  5HF4 A;  3CBZ A;  2UZC A;  1LCY A;  1KEF A;  1QAV B;  3E17 A;  2M0Z A;  2JRE A;  1QLC A;  2QKT A;  1V62 A;  2LC6 A;  3QJN A;  2DKR A;  1UEW A;  4JOH A;  1KWA A;  3OU0 A;  2Q3G A;  3QGL A;  4WYU A;  4MPA A;  1P1E A;  3SFJ A;  5HJ1 A;  3ID4 A;  2AWW A;  2L4T A;  2FNE A;  2ENO A;  1U3B A;  3HPM A;  2VSV A;  4P0C A;  5HFD A;  2E7K A;  3QDO A;  2KG2 A;  2I1N A;  3O46 A;  1NTE A;  1MFL A;  2YUY A;  3CYY A;  4K76 A;  5FB8 C;  2QKV A;  4E35 A;  3KDK A;  2CS5 A;  4UU6 A;  2OS6 A;  1QAV A;  5HED A;  4NMP A;  2LC7 A;  4JOJ A;  1FC7 A;  3RL7 A;  2QG1 A;  2RCZ A;  1FC9 A;  1VJ6 A;  3DIW A;  2VRF A;  2G2L A;  1N99 A;  3DJA A;  3PV5 A;  3TMH A;  5E21 A;  2P3W A;  1GQ5 A;  4Z8J A;  1QAU A;  1OZI A;  3KHF A;  3MH7 A;  1WHD A;  3JXT A;  2V1W A;  1RZX A;  3GJ9 A;  5HFB A;  2ZPL A;  1K32 A;  2G5M B;  2H3L A;  1OBZ A;  2CSJ A;  1YBO A;  4FGM A;  4NNL A;  3RLE A;  5B42 A;  2EEJ A;  4N6X A;  1UHP A;  4NMV A;  3L4F D;  1V1T A;  3NCV A;  4Q6S A;  3QJM A;  2KYL A;  4Q2P A;  4REY A;  2HE2 A;  4OEP A;  2M0U A;  3KZE A;  1N6F A;  1X45 A;  2EGK A;  2KBS A;  2OMJ A;  1TP3 A;  4NMT A;  1WF8 A;  1UEP A;  1W9O A;  3GDS A;  5ILB A;  4GHN A;  1ZUB A;  1WF7 A;  3DJ3 A;  3TSV A;  1G9O A;  4H11 A;  1V6B A;  1X5R A;  1VCW A;  2DJT A;  1SOT A;  1B8Q A;  2LA8 A;  2I6V A;  4FLN A;  2EV8 A;  1N6D A;  2DMZ A;  2O2T A;  1FC6 A;  2EEH A;  3LNY A;  2DB5 A;  2KAW A;  3ZRT A;  2JWE A;  5I7Z A;  2R4H A;  1RY4 A;  2EGO A;  2OCS A;  3STJ A;  2PNT A;  5DTH A;  4E3B A;  2I0I A;  3DJ1 A;  5D13 A;  1UEZ A;  1WG6 A;  5A2P A;  4NXQ A;  3KDG A;  2KV8 A;  5H3J A; 
#chains in the Genus database with same CATH homology
 2IWQ A;  5E22 A;  3PV2 A;  1KY9 A;  1UFX A;  2OGP A;  4Q6H A;  1I16 A;  1Q3P A;  1IU0 A;  3K82 A;  4HOP B;  1UF1 A;  1Y8T A;  2FCF A;  3I4W A;  4NMQ A;  1Z87 A;  5JXB A;  1RGW A;  2KL1 A;  2EEI A;  3K50 A;  4Q2N A;  2V90 A;  3WKM A;  2LOB A;  1BE9 A;  3CBY A;  2L4S A;  2VZ5 A;  3BPU A;  2IWP A;  5HFE A;  4YYX A;  1UIT A;  2HE4 A;  2PKU A;  2EEG A;  3GDU A;  1X5N A;  2KJP A;  2X7Z A;  2OSG A;  4JOF A;  1Q3O A;  2AIN A;  2EAQ A;  5F67 A;  5HF1 A;  2PZD A;  3I18 A;  3MH6 A;  4HOP A;  3CH8 A;  3GCN A;  1UJV A;  3GDV A;  1X9Z A;  1TP5 A;  1VA8 A;  3ID3 A;  4K6Y A;  1UJD A;  2ZPM A;  2EHR A;  4O06 A;  3DOR A;  3MH4 A;  2YT7 A;  2PDZ A;  4L8N A;  2CSS A;  2OQS A;  3AXA A;  3EGG C;  4OAJ A;  2YT8 A;  4NXR A;  1N7E A;  4JOR A;  3R69 A;  1GM1 A;  1XZ9 A;  2D8I A;  4AMH A;  2KPL A;  3SHW A;  1BFE A;  1Q7X A;  2M3M A;  1L6O A;  4K78 A;  4E34 A;  1N6E A;  1WFG A;  1W9Q A;  4NMS A;  5E11 A;  3PS4 A;  2M0T A;  2EDZ A;  2K1Z A;  4IC6 A;  4KFV A;  2JOA A;  5HDY A;  2H3M A;  1SOZ A;  1IU2 A;  3EGH C;  4JJ0 A;  4JOG A;  2KPK A;  2PA1 A;  4OEO A;  2VPH A;  4JJ3 A;  5EZ0 A;  2DLS A;  5G1E A;  2OPG A;  5GLJ A;  2WL7 A;  5IL9 A;  5GND A;  1IHJ A;  1N7T A;  3R0H A;  5E6P B;  4GVC A;  4G69 A;  3ID2 A;  4Q2O A;  3SUZ A;  2AWU A;  2GZV A;  2M10 A;  4UU5 A;  5G1D A;  1R6J A;  2KOH A;  4NNM A;  2EXG A;  3NGH A;  3QE1 A;  3K1R A;  1MFG A;  5EYZ A;  3NFL A;  3SOE A;  4JOK A;  3CS0 A;  4R2Z A;  2KRG A;  4K72 A;  1VB7 A;  1M5Z A;  3O5N A;  2EJY A;  1I92 A;  2DM8 A;  1U37 A;  1PDR A;  4WYT A;  2IWO A;  3ID1 A;  1RGR A;  4KFW A;  5HEY A;  2OZF A;  3VQF A;  2QKU A;  1N7F A;  2FE5 A;  1GQ4 A;  3OTP A;  3NFK A;  2I4S A;  3TSZ A;  2YTW A;  1VAE A;  2RRM A;  1WFV A;  2VSP A;  1W9E A;  1Z86 A;  3VQG A;  3GGE A;  5HET A;  2K20 A;  4Z33 A;  4NMO A;  2DLU A;  1U38 A;  2Z17 A;  1UEQ A;  2GEF A;  4NMR A;  1UM1 A;  1NF3 C;  2VWR A;  4Q2Q A;  2M0V A;  3SHU A;  2BYG A;  3PV4 A;  2I0L A;  3GSL A;  5B6L A;  4NXP A;  4JOP A;  1Y7N A;  4LMM A;  1ZOK A;  2H2B A;  2IWN A;  2MX6 A;  3I1E A;  2DAZ A;  2AWX A;  3CC0 A;  4Q3H A;  4F8K A;  2PKT A;  3WKL A;  2EDP A;  1MC7 A;  2REY A;  3QIK A;  5HFC A;  1WJL A;  1UM7 A;  4EDJ A;  4JOE A;  3LNX A;  4XHV A;  1OBY A;  2F0A A;  2QBW A;  1X6D A;  5E1Y A;  2F5Y A;  1P1D A;  2QT5 A;  2Z9I A;  3HVQ C;  4JL7 A;  1X5Q A;  5F3X A;  3R68 A;  3FY5 A;  2KA9 A;  2D92 A;  2YUB A;  3PDZ A;  1OBX A;  2KJD A;  2JIN A;  1D5G A;  2JIK A;  2JXO A;  1WH1 A;  1WI2 A;  2EGN A;  2JIL A;  2LUI A;  3GCO A;  1FCF A;  2H2C A;  4PQW A;  3CBX A;  3HPK A;  2JSN A;  2W4F A;  3KZD A;  2MHO A;  2EDV A;  4GVD A;  4K75 A;  1X8S A;  1U39 A;  2I04 A;  2KQF A;  3B76 A;  1WI4 A;  1T2M A;  3RL8 A;  1TE0 A;  2W7R A;  1UJU A;  3GAB A;  1V5L A;  3PDV A;  5FHT A;  1WIF A;  1WHA A;  4P2A B;  2DC2 A;  2KJK A;  3TSW A;  4YDP A;  2L97 A;  5HEB A;  2KOJ A;  3QO6 A;  2R3Y A;  1TQ3 A;  4RI0 A;  2HGA A;  2Q9V A;  2KOM A;  2FN5 A;  5HFF A;  1V5Q A;  2D90 A;  5HF4 A;  3CBZ A;  2UZC A;  1LCY A;  1KEF A;  1QAV B;  3E17 A;  2M0Z A;  2JRE A;  1QLC A;  2QKT A;  1V62 A;  2LC6 A;  3QJN A;  2DKR A;  1UEW A;  4JOH A;  1KWA A;  3OU0 A;  2Q3G A;  3QGL A;  4WYU A;  4MPA A;  1P1E A;  3SFJ A;  5HJ1 A;  3ID4 A;  2AWW A;  2L4T A;  2FNE A;  2ENO A;  1U3B A;  3HPM A;  2VSV A;  4P0C A;  5HFD A;  2E7K A;  3QDO A;  2KG2 A;  2I1N A;  3O46 A;  1NTE A;  1MFL A;  2YUY A;  3CYY A;  4K76 A;  5FB8 C;  2QKV A;  4E35 A;  3KDK A;  2CS5 A;  4UU6 A;  2OS6 A;  1QAV A;  5HED A;  4NMP A;  2LC7 A;  4JOJ A;  1FC7 A;  3RL7 A;  2QG1 A;  2RCZ A;  1FC9 A;  1VJ6 A;  3DIW A;  2VRF A;  2G2L A;  1N99 A;  3DJA A;  3PV5 A;  3TMH A;  5E21 A;  2P3W A;  1GQ5 A;  4Z8J A;  1QAU A;  1OZI A;  3KHF A;  3MH7 A;  1WHD A;  3JXT A;  2V1W A;  1RZX A;  3GJ9 A;  5HFB A;  2ZPL A;  1K32 A;  2G5M B;  2H3L A;  1OBZ A;  2CSJ A;  1YBO A;  4FGM A;  4NNL A;  3RLE A;  5B42 A;  2EEJ A;  4N6X A;  1UHP A;  4NMV A;  3L4F D;  1V1T A;  3NCV A;  4Q6S A;  3QJM A;  2KYL A;  4Q2P A;  4REY A;  2HE2 A;  4OEP A;  2M0U A;  3KZE A;  1N6F A;  1X45 A;  2EGK A;  2KBS A;  2OMJ A;  1TP3 A;  4NMT A;  1WF8 A;  1UEP A;  1W9O A;  3GDS A;  5ILB A;  4GHN A;  1ZUB A;  1WF7 A;  3DJ3 A;  3TSV A;  1G9O A;  4H11 A;  1V6B A;  1X5R A;  1VCW A;  2DJT A;  1SOT A;  1B8Q A;  2LA8 A;  2I6V A;  4FLN A;  2EV8 A;  1N6D A;  2DMZ A;  2O2T A;  1FC6 A;  2EEH A;  3LNY A;  2DB5 A;  2KAW A;  3ZRT A;  2JWE A;  5I7Z A;  2R4H A;  1RY4 A;  2EGO A;  2OCS A;  3STJ A;  2PNT A;  5DTH A;  4E3B A;  2I0I A;  3DJ1 A;  5D13 A;  1UEZ A;  1WG6 A;  5A2P A;  4NXQ A;  3KDG A;  2KV8 A;  5H3J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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