4NXPA

Crystal structure of free t-cell lymphoma invasion and metastasis-1 pdz domain quadruple mutant (qm)
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
91
structure length
86
Chain Sequence
GKVTHSIHIEKDTYGFSLSSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAADALNSSMMEDFFSQPSVGLLVRTYPEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
total genus 18
structure length 86
sequence length 91
ec nomenclature
pdb deposition date 2013-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4nxpA00
2DMZA 1WI2A 1UEPA 5E22A 4IC6A 3E17A 3VQFA 2QG1A 3PV5A 2KJDA 2G5MB 4JOEA 5G1EA 3WKLA 4L8NA 4WYTA 3CH8A 2YTWA 3RL8A 2EAQA 2AWXA 2P3WA 2Q9VA 5HFDA 4E35A 2EV8A 1UFXA 4JOKA 2JOAA 2DB5A 4Q2NA 4OEOA 2K1ZA 2VPHA 1N6EA 3O46A 1X5QA 2Z17A 4K76A 3ID1A 2F5YA 2DLSA 3LNXA 2ZPLA 3DJAA 2H3LA 3GGEA 3CYYA 3FY5A 1KEFA 5HETA 5A2PA 2OPGA 3R68A 1NF3C 4HOPB 5H3JA 1OZIA 3O5NA 2CSJA 1QAVA 3WKMA 4KFWA 5F67A 2VSPA 4EDJA 1WJLA 2X7ZA 1BE9A 1PDRA 3L4FD 3CS0A 2DM8A 1KY9A 2KOHA 1TP5A 4K72A 2EEGA 1K32A 3AXAA 4JOHA 3ID2A 1TP3A 3K82A 2JWEA 3GCNA 2PA1A 3EGGC 5FHTA 4Q2QA 5HEBA 2D92A 4YDPA 1QAUA 2PNTA 3SFJA 2VRFA 2OQSA 1B8QA 2I4SA 3HVQC 4OAJA 1G9OA 2ZPMA 2YUBA 2LC6A 2Q3GA 2DC2A 4NNLA 1VB7A 1UJUA 2IWOA 2M10A 3TSWA 3DJ1A 2AWWA 3SOEA 2OSGA 2EEJA 1UJVA 2I0IA 3QO6A 1FCFA 3GDSA 1W9EA 3SHWA 2YT8A 2MHOA 3K1RA 5DTHA 3TSZA 3I18A 1X6DA 2DLUA 2PDZA 3QGLA 4P2AB 3ID3A 2PKUA 2D8IA 2K20A 1GM1A 1TE0A 2D90A 2BYGA 2LA8A 1UEZA 1I16A 2JXOA 1V5QA 1RGWA 1TQ3A 1UJDA 3SHUA 2PZDA 2V1WA 3DORA 2WL7A 2EDZA 2KBSA 4NMVA 5EYZA 1VA8A 2M0ZA 3B76A 3JXTA 3K50A 2OMJA 2EGKA 2KL1A 2KRGA 2IWPA 1ZOKA 1N7FA 4Z33A 3HPMA 1WF7A 2HE4A 2DKRA 4Z8JA 1R6JA 1UEWA 2QKTA 5HDYA 2QT5A 1X5NA 4WYUA 1UM7A 4N6XA 1WI4A 3KZEA 4Q6HA 3PV2A 4K75A 1V5LA 1WF8A 3MH7A 1SOTA 1M5ZA 1UEQA 2RCZA 1RZXA 4NMTA 2IWNA 3DIWA 4NMSA 1P1DA 4JL7A 3PDVA 3CC0A 3NGHA 2O2TA 1N7EA 4Q2OA 4Q6SA 4Q2PA 3STJA 2DAZA 2YT7A 1N99A 2F0AA 1Q3OA 5E6PB 1V6BA 4LMMA 1N6FA 4GVCA 4RI0A 3PV4A 5E11A 2PKTA 1OBZA 2KV8A 4GVDA 1U39A 2H2CA 3GJ9A 3NFKA 4E3BA 2I04A 3PDZA 2OGPA 4PQWA 2MX6A 2OCSA 2VZ5A 1W9OA 2KOJA 3HPKA 1I92A 1ZUBA 2L4SA 2JREA 2KQFA 4XHVA 2KG2A 4O06A 3PS4A 4G69A 1SOZA 3QIKA 4F8KA 4MPAA 4HOPA 2DJTA 3EGHC 3CBZA 2JIKA 4REYA 1L6OA 1FC6A 3CBXA 4R2ZA 3SUZA 1OBYA 1OBXA 2KYLA 2CS5A 3TMHA 1VAEA 2YUYA 1LCYA 1UF1A 2LOBA 2AWUA 1QAVB 1Q3PA 1V1TA 4NXPA 5D13A 2M0TA 1RY4A 4NMOA 2CSSA 2FCFA 4OEPA 5GNDA 1N7TA 5EZ0A 1T2MA 1FC9A 1MFGA 2ENOA 2M0UA 2EDPA 2QKVA 1W9QA 2FE5A 1QLCA 2KPLA 2EGOA 1U37A 3QJMA 2EEHA 1Y8TA 2HE2A 3GCOA 1BFEA 4K6YA 5E21A 2LC7A 5JXBA 1U3BA 4NMQA 3VQGA 4NMRA 4NXQA 1WHDA 2KJKA 2VSVA 2UZCA 3BPUA 3GSLA 5I7ZA 1P1EA 3RLEA 2OS6A 3KZDA 2W7RA 4KFVA 1UITA 2R3YA 5HF4A 1WIFA 2EDVA 2L4TA 4JORA 5HEDA 2QKUA 1N6DA 1MFLA 1Y7NA 4FGMA 1KWAA 3GDVA 3QE1A 1IU2A 2KPKA 1WG6A 2GZVA 2EGNA 5E1YA 2M0VA 2QBWA 1WFVA 1NTEA 5B6LA 3TSVA 5HFEA 1WFGA 3R69A 2L97A 4P0CA 3MH6A 3ID4A 1V62A 5HJ1A 3MH4A 5G1DA 1U38A 4E34A 2EXGA 3DJ3A 3GDUA 3OTPA 2W4FA 3I4WA 2I0LA 1GQ4A 2H2BA 2M3MA 2REYA 4K78A 1Z86A 3I1EA 3CBYA 1IHJA 1XZ9A 2KJPA 2VWRA 1VJ6A 2LUIA 4AMHA 2KA9A 5F3XA 2E7KA 5HF1A 3ZRTA 1D5GA 1X45A 1VCWA 3OU0A 4NNMA 1UM1A 3RL7A 4H11A 4NXRA 2KOMA 1X5RA 1YBOA 2R4HA 1FC7A 1UHPA 5GLJA 4GHNA 2HGAA 3NFLA 1GQ5A 2FNEA 2I6VA 2RRMA 2OZFA 4JOPA 1X8SA 5HFCA 1RGRA 2EEIA 1Q7XA 1WH1A 4UU6A 2IWQA 2H3MA 5HEYA 3QDOA 2KAWA 2I1NA 2JINA 4JOGA 2G2LA 1MC7A 1WHAA 5HFBA 2JILA 4JOFA 3KHFA 2EHRA 2FN5A 4NMPA 4Q3HA 2Z9IA 1IU0A 2AINA 5FB8C 4JOJA 5HFFA 3R0HA 3LNYA 2EJYA 1Z87A 2V90A 4YYXA 4UU5A 3QJNA
chains in the Genus database with same CATH superfamily
2DMZA 1WI2A 1UEPA 5E22A 4IC6A 3E17A 3VQFA 2QG1A 3PV5A 2KJDA 2G5MB 4JOEA 5G1EA 3WKLA 4L8NA 4WYTA 3CH8A 2YTWA 3RL8A 2EAQA 1X9ZA 2AWXA 2P3WA 2Q9VA 5HFDA 4E35A 2EV8A 1UFXA 4JOKA 2JOAA 2DB5A 4Q2NA 4OEOA 2K1ZA 2VPHA 1N6EA 3O46A 1X5QA 2Z17A 4K76A 3ID1A 2F5YA 2DLSA 3LNXA 2ZPLA 3DJAA 2H3LA 3GGEA 3CYYA 3FY5A 1KEFA 5HETA 5A2PA 2OPGA 3R68A 1NF3C 4HOPB 5H3JA 1OZIA 3O5NA 2CSJA 1QAVA 3WKMA 4KFWA 5F67A 2VSPA 4EDJA 1WJLA 2X7ZA 1BE9A 1PDRA 3L4FD 3CS0A 2DM8A 1KY9A 2KOHA 1TP5A 4K72A 2EEGA 1K32A 3AXAA 4JOHA 3ID2A 1TP3A 3K82A 2JWEA 3GCNA 2PA1A 3EGGC 5FHTA 4Q2QA 5HEBA 2D92A 4YDPA 1QAUA 2PNTA 3SFJA 2VRFA 2OQSA 1B8QA 2I4SA 3HVQC 4OAJA 1G9OA 5ILBA 2ZPMA 2YUBA 2LC6A 2Q3GA 2DC2A 4NNLA 1VB7A 1UJUA 2IWOA 2M10A 3TSWA 3DJ1A 2AWWA 3SOEA 2OSGA 2EEJA 1UJVA 2I0IA 3QO6A 1FCFA 3GDSA 1W9EA 3SHWA 2YT8A 2MHOA 3K1RA 5DTHA 3TSZA 3I18A 1X6DA 2DLUA 2PDZA 3QGLA 4P2AB 3ID3A 2PKUA 2D8IA 2K20A 1GM1A 1TE0A 2D90A 2BYGA 2LA8A 1UEZA 1I16A 2JXOA 1V5QA 1RGWA 1TQ3A 1UJDA 3SHUA 2PZDA 2V1WA 3DORA 2WL7A 2EDZA 2KBSA 4NMVA 5EYZA 1VA8A 2M0ZA 3B76A 3JXTA 3K50A 2OMJA 2EGKA 2KL1A 2KRGA 2IWPA 1ZOKA 1N7FA 4Z33A 3HPMA 4JJ3A 1WF7A 2HE4A 2DKRA 4Z8JA 1R6JA 1UEWA 2QKTA 5HDYA 2QT5A 1X5NA 4WYUA 1UM7A 4N6XA 1WI4A 3KZEA 4Q6HA 3PV2A 4K75A 1V5LA 1WF8A 3MH7A 1SOTA 1M5ZA 1UEQA 2RCZA 1RZXA 4NMTA 2IWNA 3DIWA 4NMSA 1P1DA 4JL7A 3PDVA 3CC0A 3NGHA 2O2TA 3KDKA 1N7EA 4Q2OA 4Q6SA 4Q2PA 3STJA 2DAZA 2YT7A 1N99A 2F0AA 1Q3OA 5E6PB 1V6BA 4LMMA 1N6FA 4GVCA 4RI0A 3PV4A 5E11A 2PKTA 1OBZA 2KV8A 4GVDA 1U39A 2H2CA 3GJ9A 3NFKA 4E3BA 2I04A 3PDZA 2OGPA 4PQWA 2MX6A 2OCSA 2VZ5A 1W9OA 2KOJA 3HPKA 1I92A 1ZUBA 2L4SA 2JREA 2KQFA 4XHVA 2KG2A 4O06A 3PS4A 4G69A 1SOZA 3QIKA 4F8KA 4MPAA 4HOPA 2DJTA 3EGHC 3CBZA 2JIKA 4REYA 1L6OA 1FC6A 3CBXA 4R2ZA 3SUZA 1OBYA 1OBXA 2KYLA 2CS5A 3TMHA 1VAEA 2YUYA 1LCYA 1UF1A 2LOBA 2AWUA 1QAVB 1Q3PA 1V1TA 4NXPA 5D13A 2M0TA 1RY4A 4NMOA 2CSSA 2FCFA 4OEPA 5GNDA 1N7TA 5EZ0A 1T2MA 3KDGA 3GABA 1FC9A 1MFGA 2ENOA 2M0UA 2EDPA 2QKVA 1W9QA 2FE5A 1QLCA 2KPLA 2EGOA 1U37A 3QJMA 2EEHA 1Y8TA 2HE2A 3GCOA 1BFEA 4K6YA 5E21A 2LC7A 5JXBA 1U3BA 4NMQA 3VQGA 4NMRA 4NXQA 1WHDA 2KJKA 2VSVA 2UZCA 3BPUA 3GSLA 5I7ZA 1P1EA 3RLEA 2OS6A 3KZDA 2W7RA 4KFVA 1UITA 2JSNA 2R3YA 5HF4A 1WIFA 2EDVA 2L4TA 4JORA 5HEDA 2QKUA 1N6DA 1MFLA 1Y7NA 4FGMA 1KWAA 3GDVA 3QE1A 1IU2A 2KPKA 1WG6A 2GZVA 2EGNA 5E1YA 2M0VA 4FLNA 2QBWA 1WFVA 1NTEA 5B6LA 3TSVA 5HFEA 1WFGA 3R69A 2L97A 4P0CA 3MH6A 3ID4A 1V62A 5HJ1A 3MH4A 5G1DA 1U38A 4E34A 2EXGA 3DJ3A 3GDUA 3OTPA 2W4FA 3I4WA 2I0LA 1GQ4A 2H2BA 5IL9A 2M3MA 2REYA 4K78A 1Z86A 3I1EA 3CBYA 1IHJA 1XZ9A 2KJPA 2VWRA 1VJ6A 2LUIA 4AMHA 2KA9A 5F3XA 2E7KA 5HF1A 3NCVA 3ZRTA 1D5GA 1X45A 1VCWA 3OU0A 4NNMA 1UM1A 3RL7A 4H11A 5B42A 4NXRA 2KOMA 1X5RA 1YBOA 2R4HA 1FC7A 1UHPA 5GLJA 4GHNA 2HGAA 3NFLA 1GQ5A 2FNEA 2I6VA 2RRMA 2OZFA 4JOPA 1X8SA 5HFCA 1RGRA 2EEIA 1Q7XA 1WH1A 4UU6A 2IWQA 2H3MA 5HEYA 3QDOA 2KAWA 2I1NA 2JINA 4JOGA 2G2LA 1MC7A 1WHAA 5HFBA 2JILA 4JOFA 3KHFA 2EHRA 2FN5A 4NMPA 4Q3HA 4JJ0A 2Z9IA 1IU0A 2AINA 5FB8C 2GEFA 4JOJA 5HFFA 3R0HA 3LNYA 2EJYA 1Z87A 2V90A 4YYXA 4UU5A 3QJNA
chains in the Genus database with same CATH topology
2DMZA 1WI2A 1UEPA 5E22A 4IC6A 3E17A 3VQFA 2QG1A 3PV5A 2KJDA 2G5MB 4JOEA 5G1EA 3WKLA 4L8NA 4WYTA 3CH8A 2YTWA 3RL8A 2EAQA 1X9ZA 2AWXA 2P3WA 2Q9VA 5HFDA 4E35A 2EV8A 1UFXA 4JOKA 2JOAA 2DB5A 4Q2NA 4OEOA 2K1ZA 2VPHA 1N6EA 3O46A 1X5QA 2Z17A 4K76A 3ID1A 2F5YA 2DLSA 3LNXA 2ZPLA 3DJAA 2H3LA 3GGEA 3CYYA 3FY5A 1KEFA 5HETA 5A2PA 2OPGA 3R68A 1NF3C 4HOPB 5H3JA 1OZIA 3O5NA 2CSJA 1QAVA 3WKMA 4KFWA 5F67A 2VSPA 4EDJA 1WJLA 2X7ZA 1BE9A 1PDRA 3L4FD 3CS0A 2DM8A 1KY9A 2KOHA 1TP5A 4K72A 2EEGA 1K32A 3AXAA 4JOHA 3ID2A 1TP3A 3K82A 2JWEA 3GCNA 2PA1A 3EGGC 5FHTA 4Q2QA 5HEBA 2D92A 4YDPA 1QAUA 2PNTA 3SFJA 2VRFA 2OQSA 1B8QA 2I4SA 3HVQC 4OAJA 1G9OA 5ILBA 2ZPMA 2YUBA 2LC6A 2Q3GA 2DC2A 4NNLA 1VB7A 1UJUA 2IWOA 2M10A 3TSWA 3DJ1A 2AWWA 3SOEA 2OSGA 2EEJA 1UJVA 2I0IA 3QO6A 1FCFA 3GDSA 1W9EA 3SHWA 2YT8A 2MHOA 3K1RA 5DTHA 3TSZA 3I18A 1X6DA 2DLUA 2PDZA 3QGLA 4P2AB 3ID3A 2PKUA 2D8IA 2K20A 1GM1A 1TE0A 2D90A 2BYGA 2LA8A 1UEZA 1I16A 2JXOA 1V5QA 1RGWA 1TQ3A 1UJDA 3SHUA 2PZDA 2V1WA 3DORA 2WL7A 2EDZA 2KBSA 4NMVA 5EYZA 1VA8A 2M0ZA 3B76A 3JXTA 3K50A 2OMJA 2EGKA 2KL1A 2KRGA 2IWPA 1ZOKA 1N7FA 4Z33A 3HPMA 4JJ3A 1WF7A 2HE4A 2DKRA 4Z8JA 1R6JA 1UEWA 2QKTA 5HDYA 2QT5A 1X5NA 4WYUA 1UM7A 4N6XA 1WI4A 3KZEA 4Q6HA 3PV2A 4K75A 1V5LA 1WF8A 3MH7A 1SOTA 1M5ZA 1UEQA 2RCZA 1RZXA 4NMTA 2IWNA 3DIWA 4NMSA 1P1DA 4JL7A 3PDVA 3CC0A 3NGHA 2O2TA 3KDKA 1N7EA 4Q2OA 4Q6SA 4Q2PA 3STJA 2DAZA 2YT7A 1N99A 2F0AA 1Q3OA 5E6PB 1V6BA 4LMMA 1N6FA 4GVCA 4RI0A 3PV4A 5E11A 2PKTA 1OBZA 2KV8A 4GVDA 1U39A 2H2CA 3GJ9A 3NFKA 4E3BA 2I04A 3PDZA 2OGPA 4PQWA 2MX6A 2OCSA 2VZ5A 1W9OA 2KOJA 3HPKA 1I92A 1ZUBA 2L4SA 2JREA 2KQFA 4XHVA 2KG2A 4O06A 3PS4A 4G69A 1SOZA 3QIKA 4F8KA 4MPAA 4HOPA 2DJTA 3EGHC 3CBZA 2JIKA 4REYA 1L6OA 1FC6A 3CBXA 4R2ZA 3SUZA 1OBYA 1OBXA 2KYLA 2CS5A 3TMHA 1VAEA 2YUYA 1LCYA 1UF1A 2LOBA 2AWUA 1QAVB 1Q3PA 1V1TA 4NXPA 5D13A 2M0TA 1RY4A 4NMOA 2CSSA 2FCFA 4OEPA 5GNDA 1N7TA 5EZ0A 1T2MA 3KDGA 3GABA 1FC9A 1MFGA 2ENOA 2M0UA 2EDPA 2QKVA 1W9QA 2FE5A 1QLCA 2KPLA 2EGOA 1U37A 3QJMA 2EEHA 1Y8TA 2HE2A 3GCOA 1BFEA 4K6YA 5E21A 2LC7A 5JXBA 1U3BA 4NMQA 3VQGA 4NMRA 4NXQA 1WHDA 2KJKA 2VSVA 2UZCA 3BPUA 3GSLA 5I7ZA 1P1EA 3RLEA 2OS6A 3KZDA 2W7RA 4KFVA 1UITA 2JSNA 2R3YA 5HF4A 1WIFA 2EDVA 2L4TA 4JORA 5HEDA 2QKUA 1N6DA 1MFLA 1Y7NA 4FGMA 1KWAA 3GDVA 3QE1A 1IU2A 2KPKA 1WG6A 2GZVA 2EGNA 5E1YA 2M0VA 4FLNA 2QBWA 1WFVA 1NTEA 5B6LA 3TSVA 5HFEA 1WFGA 3R69A 2L97A 4P0CA 3MH6A 3ID4A 1V62A 5HJ1A 3MH4A 5G1DA 1U38A 4E34A 2EXGA 3DJ3A 3GDUA 3OTPA 2W4FA 3I4WA 2I0LA 1GQ4A 2H2BA 5IL9A 2M3MA 2REYA 4K78A 1Z86A 3I1EA 3CBYA 1IHJA 1XZ9A 2KJPA 2VWRA 1VJ6A 2LUIA 4AMHA 2KA9A 5F3XA 2E7KA 5HF1A 3NCVA 3ZRTA 1D5GA 1X45A 1VCWA 3OU0A 4NNMA 1UM1A 3RL7A 4H11A 5B42A 4NXRA 2KOMA 1X5RA 1YBOA 2R4HA 1FC7A 1UHPA 5GLJA 4GHNA 2HGAA 3NFLA 1GQ5A 2FNEA 2I6VA 2RRMA 2OZFA 4JOPA 1X8SA 5HFCA 1RGRA 2EEIA 1Q7XA 1WH1A 4UU6A 2IWQA 2H3MA 5HEYA 3QDOA 2KAWA 2I1NA 2JINA 4JOGA 2G2LA 1MC7A 1WHAA 5HFBA 2JILA 4JOFA 3KHFA 2EHRA 2FN5A 4NMPA 4Q3HA 4JJ0A 2Z9IA 1IU0A 2AINA 5FB8C 2GEFA 4JOJA 5HFFA 3R0HA 3LNYA 2EJYA 1Z87A 2V90A 4YYXA 4UU5A 3QJNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DMZ A;  1WI2 A;  1UEP A;  5E22 A;  4IC6 A;  3E17 A;  3VQF A;  2QG1 A;  3PV5 A;  2KJD A;  2G5M B;  4JOE A;  5G1E A;  3WKL A;  4L8N A;  4WYT A;  3CH8 A;  2YTW A;  3RL8 A;  2EAQ A;  2AWX A;  2P3W A;  2Q9V A;  5HFD A;  4E35 A;  2EV8 A;  1UFX A;  4JOK A;  2JOA A;  2DB5 A;  4Q2N A;  4OEO A;  2K1Z A;  2VPH A;  1N6E A;  3O46 A;  1X5Q A;  2Z17 A;  4K76 A;  3ID1 A;  2F5Y A;  2DLS A;  3LNX A;  2ZPL A;  3DJA A;  2H3L A;  3GGE A;  3CYY A;  3FY5 A;  1KEF A;  5HET A;  5A2P A;  2OPG A;  3R68 A;  1NF3 C;  4HOP B;  5H3J A;  1OZI A;  3O5N A;  2CSJ A;  1QAV A;  3WKM A;  4KFW A;  5F67 A;  2VSP A;  4EDJ A;  1WJL A;  2X7Z A;  1BE9 A;  1PDR A;  3L4F D;  3CS0 A;  2DM8 A;  1KY9 A;  2KOH A;  1TP5 A;  4K72 A;  2EEG A;  1K32 A;  3AXA A;  4JOH A;  3ID2 A;  1TP3 A;  3K82 A;  2JWE A;  3GCN A;  2PA1 A;  3EGG C;  5FHT A;  4Q2Q A;  5HEB A;  2D92 A;  4YDP A;  1QAU A;  2PNT A;  3SFJ A;  2VRF A;  2OQS A;  1B8Q A;  2I4S A;  3HVQ C;  4OAJ A;  1G9O A;  2ZPM A;  2YUB A;  2LC6 A;  2Q3G A;  2DC2 A;  4NNL A;  1VB7 A;  1UJU A;  2IWO A;  2M10 A;  3TSW A;  3DJ1 A;  2AWW A;  3SOE A;  2OSG A;  2EEJ A;  1UJV A;  2I0I A;  3QO6 A;  1FCF A;  3GDS A;  1W9E A;  3SHW A;  2YT8 A;  2MHO A;  3K1R A;  5DTH A;  3TSZ A;  3I18 A;  1X6D A;  2DLU A;  2PDZ A;  3QGL A;  4P2A B;  3ID3 A;  2PKU A;  2D8I A;  2K20 A;  1GM1 A;  1TE0 A;  2D90 A;  2BYG A;  2LA8 A;  1UEZ A;  1I16 A;  2JXO A;  1V5Q A;  1RGW A;  1TQ3 A;  1UJD A;  3SHU A;  2PZD A;  2V1W A;  3DOR A;  2WL7 A;  2EDZ A;  2KBS A;  4NMV A;  5EYZ A;  1VA8 A;  2M0Z A;  3B76 A;  3JXT A;  3K50 A;  2OMJ A;  2EGK A;  2KL1 A;  2KRG A;  2IWP A;  1ZOK A;  1N7F A;  4Z33 A;  3HPM A;  1WF7 A;  2HE4 A;  2DKR A;  4Z8J A;  1R6J A;  1UEW A;  2QKT A;  5HDY A;  2QT5 A;  1X5N A;  4WYU A;  1UM7 A;  4N6X A;  1WI4 A;  3KZE A;  4Q6H A;  3PV2 A;  4K75 A;  1V5L A;  1WF8 A;  3MH7 A;  1SOT A;  1M5Z A;  1UEQ A;  2RCZ A;  1RZX A;  4NMT A;  2IWN A;  3DIW A;  4NMS A;  1P1D A;  4JL7 A;  3PDV A;  3CC0 A;  3NGH A;  2O2T A;  1N7E A;  4Q2O A;  4Q6S A;  4Q2P A;  3STJ A;  2DAZ A;  2YT7 A;  1N99 A;  2F0A A;  1Q3O A;  5E6P B;  1V6B A;  4LMM A;  1N6F A;  4GVC A;  4RI0 A;  3PV4 A;  5E11 A;  2PKT A;  1OBZ A;  2KV8 A;  4GVD A;  1U39 A;  2H2C A;  3GJ9 A;  3NFK A;  4E3B A;  2I04 A;  3PDZ A;  2OGP A;  4PQW A;  2MX6 A;  2OCS A;  2VZ5 A;  1W9O A;  2KOJ A;  3HPK A;  1I92 A;  1ZUB A;  2L4S A;  2JRE A;  2KQF A;  4XHV A;  2KG2 A;  4O06 A;  3PS4 A;  4G69 A;  1SOZ A;  3QIK A;  4F8K A;  4MPA A;  4HOP A;  2DJT A;  3EGH C;  3CBZ A;  2JIK A;  4REY A;  1L6O A;  1FC6 A;  3CBX A;  4R2Z A;  3SUZ A;  1OBY A;  1OBX A;  2KYL A;  2CS5 A;  3TMH A;  1VAE A;  2YUY A;  1LCY A;  1UF1 A;  2LOB A;  2AWU A;  1QAV B;  1Q3P A;  1V1T A;  4NXP A;  5D13 A;  2M0T A;  1RY4 A;  4NMO A;  2CSS A;  2FCF A;  4OEP A;  5GND A;  1N7T A;  5EZ0 A;  1T2M A;  1FC9 A;  1MFG A;  2ENO A;  2M0U A;  2EDP A;  2QKV A;  1W9Q A;  2FE5 A;  1QLC A;  2KPL A;  2EGO A;  1U37 A;  3QJM A;  2EEH A;  1Y8T A;  2HE2 A;  3GCO A;  1BFE A;  4K6Y A;  5E21 A;  2LC7 A;  5JXB A;  1U3B A;  4NMQ A;  3VQG A;  4NMR A;  4NXQ A;  1WHD A;  2KJK A;  2VSV A;  2UZC A;  3BPU A;  3GSL A;  5I7Z A;  1P1E A;  3RLE A;  2OS6 A;  3KZD A;  2W7R A;  4KFV A;  1UIT A;  2R3Y A;  5HF4 A;  1WIF A;  2EDV A;  2L4T A;  4JOR A;  5HED A;  2QKU A;  1N6D A;  1MFL A;  1Y7N A;  4FGM A;  1KWA A;  3GDV A;  3QE1 A;  1IU2 A;  2KPK A;  1WG6 A;  2GZV A;  2EGN A;  5E1Y A;  2M0V A;  2QBW A;  1WFV A;  1NTE A;  5B6L A;  3TSV A;  5HFE A;  1WFG A;  3R69 A;  2L97 A;  4P0C A;  3MH6 A;  3ID4 A;  1V62 A;  5HJ1 A;  3MH4 A;  5G1D A;  1U38 A;  4E34 A;  2EXG A;  3DJ3 A;  3GDU A;  3OTP A;  2W4F A;  3I4W A;  2I0L A;  1GQ4 A;  2H2B A;  2M3M A;  2REY A;  4K78 A;  1Z86 A;  3I1E A;  3CBY A;  1IHJ A;  1XZ9 A;  2KJP A;  2VWR A;  1VJ6 A;  2LUI A;  4AMH A;  2KA9 A;  5F3X A;  2E7K A;  5HF1 A;  3ZRT A;  1D5G A;  1X45 A;  1VCW A;  3OU0 A;  4NNM A;  1UM1 A;  3RL7 A;  4H11 A;  4NXR A;  2KOM A;  1X5R A;  1YBO A;  2R4H A;  1FC7 A;  1UHP A;  5GLJ A;  4GHN A;  2HGA A;  3NFL A;  1GQ5 A;  2FNE A;  2I6V A;  2RRM A;  2OZF A;  4JOP A;  1X8S A;  5HFC A;  1RGR A;  2EEI A;  1Q7X A;  1WH1 A;  4UU6 A;  2IWQ A;  2H3M A;  5HEY A;  3QDO A;  2KAW A;  2I1N A;  2JIN A;  4JOG A;  2G2L A;  1MC7 A;  1WHA A;  5HFB A;  2JIL A;  4JOF A;  3KHF A;  2EHR A;  2FN5 A;  4NMP A;  4Q3H A;  2Z9I A;  1IU0 A;  2AIN A;  5FB8 C;  4JOJ A;  5HFF A;  3R0H A;  3LNY A;  2EJY A;  1Z87 A;  2V90 A;  4YYX A;  4UU5 A;  3QJN A; 
#chains in the Genus database with same CATH topology
 2DMZ A;  1WI2 A;  1UEP A;  5E22 A;  4IC6 A;  3E17 A;  3VQF A;  2QG1 A;  3PV5 A;  2KJD A;  2G5M B;  4JOE A;  5G1E A;  3WKL A;  4L8N A;  4WYT A;  3CH8 A;  2YTW A;  3RL8 A;  2EAQ A;  1X9Z A;  2AWX A;  2P3W A;  2Q9V A;  5HFD A;  4E35 A;  2EV8 A;  1UFX A;  4JOK A;  2JOA A;  2DB5 A;  4Q2N A;  4OEO A;  2K1Z A;  2VPH A;  1N6E A;  3O46 A;  1X5Q A;  2Z17 A;  4K76 A;  3ID1 A;  2F5Y A;  2DLS A;  3LNX A;  2ZPL A;  3DJA A;  2H3L A;  3GGE A;  3CYY A;  3FY5 A;  1KEF A;  5HET A;  5A2P A;  2OPG A;  3R68 A;  1NF3 C;  4HOP B;  5H3J A;  1OZI A;  3O5N A;  2CSJ A;  1QAV A;  3WKM A;  4KFW A;  5F67 A;  2VSP A;  4EDJ A;  1WJL A;  2X7Z A;  1BE9 A;  1PDR A;  3L4F D;  3CS0 A;  2DM8 A;  1KY9 A;  2KOH A;  1TP5 A;  4K72 A;  2EEG A;  1K32 A;  3AXA A;  4JOH A;  3ID2 A;  1TP3 A;  3K82 A;  2JWE A;  3GCN A;  2PA1 A;  3EGG C;  5FHT A;  4Q2Q A;  5HEB A;  2D92 A;  4YDP A;  1QAU A;  2PNT A;  3SFJ A;  2VRF A;  2OQS A;  1B8Q A;  2I4S A;  3HVQ C;  4OAJ A;  1G9O A;  5ILB A;  2ZPM A;  2YUB A;  2LC6 A;  2Q3G A;  2DC2 A;  4NNL A;  1VB7 A;  1UJU A;  2IWO A;  2M10 A;  3TSW A;  3DJ1 A;  2AWW A;  3SOE A;  2OSG A;  2EEJ A;  1UJV A;  2I0I A;  3QO6 A;  1FCF A;  3GDS A;  1W9E A;  3SHW A;  2YT8 A;  2MHO A;  3K1R A;  5DTH A;  3TSZ A;  3I18 A;  1X6D A;  2DLU A;  2PDZ A;  3QGL A;  4P2A B;  3ID3 A;  2PKU A;  2D8I A;  2K20 A;  1GM1 A;  1TE0 A;  2D90 A;  2BYG A;  2LA8 A;  1UEZ A;  1I16 A;  2JXO A;  1V5Q A;  1RGW A;  1TQ3 A;  1UJD A;  3SHU A;  2PZD A;  2V1W A;  3DOR A;  2WL7 A;  2EDZ A;  2KBS A;  4NMV A;  5EYZ A;  1VA8 A;  2M0Z A;  3B76 A;  3JXT A;  3K50 A;  2OMJ A;  2EGK A;  2KL1 A;  2KRG A;  2IWP A;  1ZOK A;  1N7F A;  4Z33 A;  3HPM A;  4JJ3 A;  1WF7 A;  2HE4 A;  2DKR A;  4Z8J A;  1R6J A;  1UEW A;  2QKT A;  5HDY A;  2QT5 A;  1X5N A;  4WYU A;  1UM7 A;  4N6X A;  1WI4 A;  3KZE A;  4Q6H A;  3PV2 A;  4K75 A;  1V5L A;  1WF8 A;  3MH7 A;  1SOT A;  1M5Z A;  1UEQ A;  2RCZ A;  1RZX A;  4NMT A;  2IWN A;  3DIW A;  4NMS A;  1P1D A;  4JL7 A;  3PDV A;  3CC0 A;  3NGH A;  2O2T A;  3KDK A;  1N7E A;  4Q2O A;  4Q6S A;  4Q2P A;  3STJ A;  2DAZ A;  2YT7 A;  1N99 A;  2F0A A;  1Q3O A;  5E6P B;  1V6B A;  4LMM A;  1N6F A;  4GVC A;  4RI0 A;  3PV4 A;  5E11 A;  2PKT A;  1OBZ A;  2KV8 A;  4GVD A;  1U39 A;  2H2C A;  3GJ9 A;  3NFK A;  4E3B A;  2I04 A;  3PDZ A;  2OGP A;  4PQW A;  2MX6 A;  2OCS A;  2VZ5 A;  1W9O A;  2KOJ A;  3HPK A;  1I92 A;  1ZUB A;  2L4S A;  2JRE A;  2KQF A;  4XHV A;  2KG2 A;  4O06 A;  3PS4 A;  4G69 A;  1SOZ A;  3QIK A;  4F8K A;  4MPA A;  4HOP A;  2DJT A;  3EGH C;  3CBZ A;  2JIK A;  4REY A;  1L6O A;  1FC6 A;  3CBX A;  4R2Z A;  3SUZ A;  1OBY A;  1OBX A;  2KYL A;  2CS5 A;  3TMH A;  1VAE A;  2YUY A;  1LCY A;  1UF1 A;  2LOB A;  2AWU A;  1QAV B;  1Q3P A;  1V1T A;  4NXP A;  5D13 A;  2M0T A;  1RY4 A;  4NMO A;  2CSS A;  2FCF A;  4OEP A;  5GND A;  1N7T A;  5EZ0 A;  1T2M A;  3KDG A;  3GAB A;  1FC9 A;  1MFG A;  2ENO A;  2M0U A;  2EDP A;  2QKV A;  1W9Q A;  2FE5 A;  1QLC A;  2KPL A;  2EGO A;  1U37 A;  3QJM A;  2EEH A;  1Y8T A;  2HE2 A;  3GCO A;  1BFE A;  4K6Y A;  5E21 A;  2LC7 A;  5JXB A;  1U3B A;  4NMQ A;  3VQG A;  4NMR A;  4NXQ A;  1WHD A;  2KJK A;  2VSV A;  2UZC A;  3BPU A;  3GSL A;  5I7Z A;  1P1E A;  3RLE A;  2OS6 A;  3KZD A;  2W7R A;  4KFV A;  1UIT A;  2JSN A;  2R3Y A;  5HF4 A;  1WIF A;  2EDV A;  2L4T A;  4JOR A;  5HED A;  2QKU A;  1N6D A;  1MFL A;  1Y7N A;  4FGM A;  1KWA A;  3GDV A;  3QE1 A;  1IU2 A;  2KPK A;  1WG6 A;  2GZV A;  2EGN A;  5E1Y A;  2M0V A;  4FLN A;  2QBW A;  1WFV A;  1NTE A;  5B6L A;  3TSV A;  5HFE A;  1WFG A;  3R69 A;  2L97 A;  4P0C A;  3MH6 A;  3ID4 A;  1V62 A;  5HJ1 A;  3MH4 A;  5G1D A;  1U38 A;  4E34 A;  2EXG A;  3DJ3 A;  3GDU A;  3OTP A;  2W4F A;  3I4W A;  2I0L A;  1GQ4 A;  2H2B A;  5IL9 A;  2M3M A;  2REY A;  4K78 A;  1Z86 A;  3I1E A;  3CBY A;  1IHJ A;  1XZ9 A;  2KJP A;  2VWR A;  1VJ6 A;  2LUI A;  4AMH A;  2KA9 A;  5F3X A;  2E7K A;  5HF1 A;  3NCV A;  3ZRT A;  1D5G A;  1X45 A;  1VCW A;  3OU0 A;  4NNM A;  1UM1 A;  3RL7 A;  4H11 A;  5B42 A;  4NXR A;  2KOM A;  1X5R A;  1YBO A;  2R4H A;  1FC7 A;  1UHP A;  5GLJ A;  4GHN A;  2HGA A;  3NFL A;  1GQ5 A;  2FNE A;  2I6V A;  2RRM A;  2OZF A;  4JOP A;  1X8S A;  5HFC A;  1RGR A;  2EEI A;  1Q7X A;  1WH1 A;  4UU6 A;  2IWQ A;  2H3M A;  5HEY A;  3QDO A;  2KAW A;  2I1N A;  2JIN A;  4JOG A;  2G2L A;  1MC7 A;  1WHA A;  5HFB A;  2JIL A;  4JOF A;  3KHF A;  2EHR A;  2FN5 A;  4NMP A;  4Q3H A;  4JJ0 A;  2Z9I A;  1IU0 A;  2AIN A;  5FB8 C;  2GEF A;  4JOJ A;  5HFF A;  3R0H A;  3LNY A;  2EJY A;  1Z87 A;  2V90 A;  4YYX A;  4UU5 A;  3QJN A; 
#chains in the Genus database with same CATH homology
 2DMZ A;  1WI2 A;  1UEP A;  5E22 A;  4IC6 A;  3E17 A;  3VQF A;  2QG1 A;  3PV5 A;  2KJD A;  2G5M B;  4JOE A;  5G1E A;  3WKL A;  4L8N A;  4WYT A;  3CH8 A;  2YTW A;  3RL8 A;  2EAQ A;  1X9Z A;  2AWX A;  2P3W A;  2Q9V A;  5HFD A;  4E35 A;  2EV8 A;  1UFX A;  4JOK A;  2JOA A;  2DB5 A;  4Q2N A;  4OEO A;  2K1Z A;  2VPH A;  1N6E A;  3O46 A;  1X5Q A;  2Z17 A;  4K76 A;  3ID1 A;  2F5Y A;  2DLS A;  3LNX A;  2ZPL A;  3DJA A;  2H3L A;  3GGE A;  3CYY A;  3FY5 A;  1KEF A;  5HET A;  5A2P A;  2OPG A;  3R68 A;  1NF3 C;  4HOP B;  5H3J A;  1OZI A;  3O5N A;  2CSJ A;  1QAV A;  3WKM A;  4KFW A;  5F67 A;  2VSP A;  4EDJ A;  1WJL A;  2X7Z A;  1BE9 A;  1PDR A;  3L4F D;  3CS0 A;  2DM8 A;  1KY9 A;  2KOH A;  1TP5 A;  4K72 A;  2EEG A;  1K32 A;  3AXA A;  4JOH A;  3ID2 A;  1TP3 A;  3K82 A;  2JWE A;  3GCN A;  2PA1 A;  3EGG C;  5FHT A;  4Q2Q A;  5HEB A;  2D92 A;  4YDP A;  1QAU A;  2PNT A;  3SFJ A;  2VRF A;  2OQS A;  1B8Q A;  2I4S A;  3HVQ C;  4OAJ A;  1G9O A;  5ILB A;  2ZPM A;  2YUB A;  2LC6 A;  2Q3G A;  2DC2 A;  4NNL A;  1VB7 A;  1UJU A;  2IWO A;  2M10 A;  3TSW A;  3DJ1 A;  2AWW A;  3SOE A;  2OSG A;  2EEJ A;  1UJV A;  2I0I A;  3QO6 A;  1FCF A;  3GDS A;  1W9E A;  3SHW A;  2YT8 A;  2MHO A;  3K1R A;  5DTH A;  3TSZ A;  3I18 A;  1X6D A;  2DLU A;  2PDZ A;  3QGL A;  4P2A B;  3ID3 A;  2PKU A;  2D8I A;  2K20 A;  1GM1 A;  1TE0 A;  2D90 A;  2BYG A;  2LA8 A;  1UEZ A;  1I16 A;  2JXO A;  1V5Q A;  1RGW A;  1TQ3 A;  1UJD A;  3SHU A;  2PZD A;  2V1W A;  3DOR A;  2WL7 A;  2EDZ A;  2KBS A;  4NMV A;  5EYZ A;  1VA8 A;  2M0Z A;  3B76 A;  3JXT A;  3K50 A;  2OMJ A;  2EGK A;  2KL1 A;  2KRG A;  2IWP A;  1ZOK A;  1N7F A;  4Z33 A;  3HPM A;  4JJ3 A;  1WF7 A;  2HE4 A;  2DKR A;  4Z8J A;  1R6J A;  1UEW A;  2QKT A;  5HDY A;  2QT5 A;  1X5N A;  4WYU A;  1UM7 A;  4N6X A;  1WI4 A;  3KZE A;  4Q6H A;  3PV2 A;  4K75 A;  1V5L A;  1WF8 A;  3MH7 A;  1SOT A;  1M5Z A;  1UEQ A;  2RCZ A;  1RZX A;  4NMT A;  2IWN A;  3DIW A;  4NMS A;  1P1D A;  4JL7 A;  3PDV A;  3CC0 A;  3NGH A;  2O2T A;  3KDK A;  1N7E A;  4Q2O A;  4Q6S A;  4Q2P A;  3STJ A;  2DAZ A;  2YT7 A;  1N99 A;  2F0A A;  1Q3O A;  5E6P B;  1V6B A;  4LMM A;  1N6F A;  4GVC A;  4RI0 A;  3PV4 A;  5E11 A;  2PKT A;  1OBZ A;  2KV8 A;  4GVD A;  1U39 A;  2H2C A;  3GJ9 A;  3NFK A;  4E3B A;  2I04 A;  3PDZ A;  2OGP A;  4PQW A;  2MX6 A;  2OCS A;  2VZ5 A;  1W9O A;  2KOJ A;  3HPK A;  1I92 A;  1ZUB A;  2L4S A;  2JRE A;  2KQF A;  4XHV A;  2KG2 A;  4O06 A;  3PS4 A;  4G69 A;  1SOZ A;  3QIK A;  4F8K A;  4MPA A;  4HOP A;  2DJT A;  3EGH C;  3CBZ A;  2JIK A;  4REY A;  1L6O A;  1FC6 A;  3CBX A;  4R2Z A;  3SUZ A;  1OBY A;  1OBX A;  2KYL A;  2CS5 A;  3TMH A;  1VAE A;  2YUY A;  1LCY A;  1UF1 A;  2LOB A;  2AWU A;  1QAV B;  1Q3P A;  1V1T A;  4NXP A;  5D13 A;  2M0T A;  1RY4 A;  4NMO A;  2CSS A;  2FCF A;  4OEP A;  5GND A;  1N7T A;  5EZ0 A;  1T2M A;  3KDG A;  3GAB A;  1FC9 A;  1MFG A;  2ENO A;  2M0U A;  2EDP A;  2QKV A;  1W9Q A;  2FE5 A;  1QLC A;  2KPL A;  2EGO A;  1U37 A;  3QJM A;  2EEH A;  1Y8T A;  2HE2 A;  3GCO A;  1BFE A;  4K6Y A;  5E21 A;  2LC7 A;  5JXB A;  1U3B A;  4NMQ A;  3VQG A;  4NMR A;  4NXQ A;  1WHD A;  2KJK A;  2VSV A;  2UZC A;  3BPU A;  3GSL A;  5I7Z A;  1P1E A;  3RLE A;  2OS6 A;  3KZD A;  2W7R A;  4KFV A;  1UIT A;  2JSN A;  2R3Y A;  5HF4 A;  1WIF A;  2EDV A;  2L4T A;  4JOR A;  5HED A;  2QKU A;  1N6D A;  1MFL A;  1Y7N A;  4FGM A;  1KWA A;  3GDV A;  3QE1 A;  1IU2 A;  2KPK A;  1WG6 A;  2GZV A;  2EGN A;  5E1Y A;  2M0V A;  4FLN A;  2QBW A;  1WFV A;  1NTE A;  5B6L A;  3TSV A;  5HFE A;  1WFG A;  3R69 A;  2L97 A;  4P0C A;  3MH6 A;  3ID4 A;  1V62 A;  5HJ1 A;  3MH4 A;  5G1D A;  1U38 A;  4E34 A;  2EXG A;  3DJ3 A;  3GDU A;  3OTP A;  2W4F A;  3I4W A;  2I0L A;  1GQ4 A;  2H2B A;  5IL9 A;  2M3M A;  2REY A;  4K78 A;  1Z86 A;  3I1E A;  3CBY A;  1IHJ A;  1XZ9 A;  2KJP A;  2VWR A;  1VJ6 A;  2LUI A;  4AMH A;  2KA9 A;  5F3X A;  2E7K A;  5HF1 A;  3NCV A;  3ZRT A;  1D5G A;  1X45 A;  1VCW A;  3OU0 A;  4NNM A;  1UM1 A;  3RL7 A;  4H11 A;  5B42 A;  4NXR A;  2KOM A;  1X5R A;  1YBO A;  2R4H A;  1FC7 A;  1UHP A;  5GLJ A;  4GHN A;  2HGA A;  3NFL A;  1GQ5 A;  2FNE A;  2I6V A;  2RRM A;  2OZF A;  4JOP A;  1X8S A;  5HFC A;  1RGR A;  2EEI A;  1Q7X A;  1WH1 A;  4UU6 A;  2IWQ A;  2H3M A;  5HEY A;  3QDO A;  2KAW A;  2I1N A;  2JIN A;  4JOG A;  2G2L A;  1MC7 A;  1WHA A;  5HFB A;  2JIL A;  4JOF A;  3KHF A;  2EHR A;  2FN5 A;  4NMP A;  4Q3H A;  4JJ0 A;  2Z9I A;  1IU0 A;  2AIN A;  5FB8 C;  2GEF A;  4JOJ A;  5HFF A;  3R0H A;  3LNY A;  2EJY A;  1Z87 A;  2V90 A;  4YYX A;  4UU5 A;  3QJN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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