4AMHA

Influence of circular permutation on the folding pathway of a pdz domain
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
94
structure length
94
Chain Sequence
SKGLGFSIAGGVGNQHWPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVALEEVTHEEAVTALKNTSDFVYLKVAKPGSGEKIMEIKLIKG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Tolerance of Protein Folding to a Circular Permutation in a Pdz Domain
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords DISKS LARGE HOMOLOG 1
total genus 19
structure length 94
sequence length 94
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4amhA00
3OU0A 1N7FA 3KZEA 5EYZA 1IU0A 1UFXA 2I4SA 1UJDA 2VRFA 4JOEA 1W9EA 4L8NA 5E1YA 1U3BA 2DB5A 3GDVA 3CBZA 2AWUA 2EXGA 4H11A 2CSJA 3R69A 3NFLA 5I7ZA 2KA9A 2VWRA 4NXPA 1FC9A 3PV2A 2BYGA 3SFJA 3TMHA 3CYYA 1WJLA 1RZXA 3DIWA 1RGRA 3I18A 2YT8A 2I1NA 1V5QA 3BPUA 2W7RA 2IWQA 1WF8A 3SUZA 5HF1A 3R0HA 2OGPA 4Q3HA 5HFCA 4Q6SA 2QBWA 1ZOKA 4PQWA 5HEBA 4E3BA 1VCWA 3ID1A 2K20A 2V1WA 3LNXA 1U38A 4OAJA 4Q2QA 4F8KA 4Q2NA 5DTHA 2DKRA 4EDJA 3GDUA 1X5QA 2KJDA 4XHVA 1Q3PA 1Y8TA 2HGAA 3GJ9A 3CS0A 2V90A 1UM1A 4OEPA 2OMJA 4NXQA 3ZRTA 1TQ3A 4Q2PA 1X5RA 4WYTA 2AWWA 2EJYA 4Z33A 3QJMA 4NMTA 3GSLA 2EGKA 2YUBA 4NNMA 2EEHA 1VJ6A 3GCOA 5D13A 5FB8C 2KOHA 2H2CA 2E7KA 3GGEA 4JOPA 3B76A 1X6DA 1B8QA 3E17A 1X5NA 3PS4A 1W9QA 4IC6A 1N6DA 3NFKA 5HDYA 3QIKA 1WHDA 5HFEA 2D90A 2O2TA 2M0UA 2LA8A 1QAVB 1X45A 2PKTA 2EDZA 3SHWA 4RI0A 4HOPB 3I4WA 4P0CA 5F3XA 1RGWA 1IHJA 1TP5A 4JOGA 1TP3A 1WG6A 1FC7A 3PDVA 3TSVA 2EDPA 4JL7A 1BFEA 1R6JA 1Z87A 1WF7A 2EEJA 2W4FA 2VSVA 1OBZA 3RLEA 1WH1A 2JXOA 1WI2A 1WHAA 2KV8A 4NMSA 2M0ZA 2DC2A 2I6VA 2P3WA 3RL8A 1Q3OA 2R4HA 1L6OA 4K78A 1UHPA 3HPKA 4GVDA 4FGMA 2DM8A 4WYUA 2PZDA 3O46A 1KY9A 1UM7A 5G1EA 2H2BA 1MFGA 2KPKA 5HFBA 3ID4A 3GCNA 4JOKA 2EV8A 2M10A 4JOJA 2QKUA 2VPHA 2LC7A 2KJKA 4GVCA 2M3MA 1D5GA 3PDZA 1UEZA 2UZCA 3DJ3A 3ID2A 4NMRA 3K50A 2DJTA 2KPLA 5F67A 1N7EA 4E35A 1N99A 1V62A 1P1EA 2KQFA 3GDSA 2L97A 2KYLA 3EGHC 4JORA 3FY5A 1WI4A 3CC0A 2JWEA 2EGNA 2JILA 3QJNA 3QE1A 1FC6A 3K82A 1QAVA 2KOJA 1QLCA 2KRGA 2EGOA 3STJA 4NMVA 1V6BA 4HOPA 1VA8A 2F0AA 4MPAA 2LC6A 2EEGA 5A2PA 4P2AB 5HFDA 4YYXA 1RY4A 3QDOA 2G2LA 5E22A 2QKTA 5HEYA 1BE9A 1V1TA 3O5NA 2D92A 3RL7A 5G1DA 2F5YA 2QT5A 2REYA 2Z9IA 5B6LA 4Q2OA 2JIKA 2ZPMA 2EEIA 4K6YA 3VQFA 2WL7A 2DLSA 2OZFA 5GNDA 3TSWA 4E34A 3ID3A 1U37A 2ENOA 2FNEA 1I16A 4UU5A 4Z8JA 1KEFA 2OS6A 3DORA 2H3MA 2H3LA 2I04A 4OEOA 3CH8A 5E21A 2CS5A 1N7TA 4K72A 4JOFA 1UJVA 1ZUBA 5HF4A 1P1DA 2DMZA 1Y7NA 2FN5A 5E6PB 2MX6A 1FCFA 4G69A 1XZ9A 4GHNA 2RRMA 2OCSA 3K1RA 3QGLA 2Q9VA 1U39A 2I0IA 2Z17A 1NF3C 3WKMA 4LMMA 2IWOA 2GZVA 3I1EA 1VB7A 2L4SA 3QO6A 2QKVA 2JREA 2K1ZA 2ZPLA 1YBOA 4K76A 4NNLA 5H3JA 1IU2A 2HE2A 2FCFA 4AMHA 1V5LA 3NGHA 2PNTA 4O06A 1I92A 2FE5A 2QG1A 3R68A 2KG2A 3CBXA 1SOTA 2M0TA 1MFLA 4Q6HA 5JXBA 4NMPA 3MH7A 1UF1A 3AXAA 2CSSA 2IWPA 2VZ5A 2HE4A 2AWXA 2IWNA 2DLUA 2LOBA 1TE0A 2OQSA 1UEWA 2X7ZA 1KWAA 1N6EA 3PV4A 1W9OA 2EAQA 3L4FD 4JOHA 1G9OA 4NMQA 3MH4A 5E11A 3KHFA 1UJUA 4K75A 1NTEA 2YUYA 2KL1A 1OBXA 1VAEA 3OTPA 3EGGC 2LUIA 5FHTA 2JINA 4NMOA 3WKLA 2PKUA 5GLJA 2AINA 1WFGA 2M0VA 3PV5A 1LCYA 1OZIA 1UEQA 1PDRA 1GQ5A 1N6FA 1X8SA 1WFVA 3LNYA 1SOZA 3SHUA 1OBYA 2JOAA 2VSPA 4REYA 2L4TA 2I0LA 1WIFA 3TSZA 4KFWA 2G5MB 3DJAA 3HVQC 4UU6A 1QAUA 4R2ZA 1UITA 1M5ZA 3HPMA 2KAWA 1GM1A 2MHOA 4N6XA 2YTWA 1UEPA 1K32A 4NXRA 1T2MA 2R3YA 1MC7A 2YT7A 2KBSA 1Q7XA 2RCZA 2Q3GA 5HETA 2KOMA 3KZDA 5HEDA 5HJ1A 3MH6A 3CBYA 4KFVA 1GQ4A 2OPGA 2PA1A 2EDVA 1Z86A 3VQGA 5HFFA 4YDPA 2D8IA 5EZ0A 3SOEA 2PDZA 2DAZA 2KJPA 3DJ1A 2OSGA 3JXTA 2EHRA
chains in the Genus database with same CATH superfamily
3OU0A 1N7FA 3KZEA 5EYZA 1IU0A 1UFXA 2I4SA 1UJDA 2VRFA 4JOEA 1W9EA 4L8NA 5E1YA 1U3BA 2DB5A 3GDVA 3CBZA 2AWUA 2EXGA 4H11A 2CSJA 3R69A 3NFLA 5I7ZA 2KA9A 2VWRA 4NXPA 1FC9A 3PV2A 2BYGA 3SFJA 3TMHA 3CYYA 1WJLA 1RZXA 3DIWA 1RGRA 3I18A 2YT8A 2I1NA 1V5QA 3BPUA 2W7RA 2IWQA 1WF8A 3SUZA 5HF1A 3R0HA 2OGPA 4Q3HA 5HFCA 4Q6SA 2QBWA 1ZOKA 4PQWA 5HEBA 4E3BA 1VCWA 3ID1A 2K20A 2V1WA 3LNXA 1U38A 4OAJA 4Q2QA 4F8KA 4Q2NA 2GEFA 5DTHA 2DKRA 4EDJA 3GDUA 1X5QA 2KJDA 4XHVA 1Q3PA 1Y8TA 2HGAA 3GJ9A 3CS0A 2V90A 1UM1A 4OEPA 2OMJA 4NXQA 3ZRTA 1TQ3A 4Q2PA 1X5RA 4WYTA 2AWWA 2EJYA 4Z33A 3QJMA 4NMTA 3GSLA 2EGKA 2YUBA 4NNMA 2EEHA 1VJ6A 3GCOA 5D13A 5FB8C 2KOHA 2H2CA 2E7KA 3GGEA 4JOPA 3B76A 1X6DA 1B8QA 3E17A 1X5NA 3PS4A 1W9QA 4IC6A 1N6DA 3NFKA 5HDYA 3QIKA 1WHDA 5HFEA 2D90A 2O2TA 2M0UA 2LA8A 1QAVB 1X45A 2PKTA 2EDZA 3SHWA 4RI0A 4HOPB 3I4WA 4P0CA 5F3XA 1RGWA 1IHJA 1TP5A 4JOGA 1TP3A 1WG6A 3GABA 1FC7A 3PDVA 3TSVA 2EDPA 4JL7A 1BFEA 1R6JA 1Z87A 1WF7A 2EEJA 2W4FA 2VSVA 1OBZA 3RLEA 1WH1A 2JXOA 1WI2A 1WHAA 2KV8A 4NMSA 2M0ZA 2DC2A 2I6VA 2P3WA 3RL8A 1Q3OA 2R4HA 3KDKA 1L6OA 4K78A 1UHPA 3HPKA 4GVDA 1X9ZA 3NCVA 4FGMA 2DM8A 4WYUA 2PZDA 3O46A 1KY9A 1UM7A 5G1EA 2H2BA 1MFGA 2KPKA 5HFBA 3ID4A 3GCNA 4JOKA 2EV8A 2M10A 4JOJA 2QKUA 2VPHA 2LC7A 2KJKA 4GVCA 4JJ3A 2M3MA 1D5GA 3PDZA 1UEZA 2UZCA 3DJ3A 3ID2A 4NMRA 3K50A 2DJTA 2KPLA 5F67A 1N7EA 4E35A 1N99A 1V62A 1P1EA 2KQFA 3GDSA 2L97A 2KYLA 3EGHC 4JORA 3FY5A 1WI4A 3CC0A 2JWEA 2EGNA 2JILA 3QJNA 3QE1A 1FC6A 3K82A 1QAVA 2KOJA 1QLCA 2KRGA 2EGOA 3STJA 4NMVA 1V6BA 4HOPA 4JJ0A 1VA8A 2F0AA 4MPAA 2LC6A 2EEGA 5A2PA 4P2AB 5HFDA 4YYXA 1RY4A 3QDOA 2G2LA 5E22A 2QKTA 5HEYA 1BE9A 1V1TA 3O5NA 2D92A 3RL7A 5G1DA 2F5YA 2QT5A 2REYA 2Z9IA 5B6LA 4Q2OA 2JIKA 5IL9A 2ZPMA 2EEIA 4K6YA 3VQFA 2WL7A 2DLSA 2OZFA 5GNDA 3TSWA 4E34A 3ID3A 1U37A 2ENOA 2FNEA 1I16A 4UU5A 4Z8JA 1KEFA 2OS6A 3DORA 2H3MA 2H3LA 2I04A 4OEOA 3CH8A 5E21A 2CS5A 1N7TA 4K72A 4JOFA 1UJVA 1ZUBA 5HF4A 1P1DA 2DMZA 1Y7NA 2FN5A 5E6PB 2MX6A 1FCFA 4G69A 1XZ9A 4GHNA 2RRMA 2OCSA 3K1RA 3QGLA 2Q9VA 1U39A 2I0IA 2Z17A 1NF3C 3WKMA 4LMMA 2IWOA 2GZVA 3I1EA 1VB7A 3KDGA 5B42A 2L4SA 3QO6A 2QKVA 2JREA 2K1ZA 2ZPLA 1YBOA 4K76A 4NNLA 5H3JA 1IU2A 2HE2A 2FCFA 4AMHA 1V5LA 3NGHA 2PNTA 4O06A 1I92A 2FE5A 2QG1A 3R68A 2KG2A 3CBXA 1SOTA 2M0TA 1MFLA 4Q6HA 5JXBA 4NMPA 3MH7A 1UF1A 3AXAA 2CSSA 2IWPA 2VZ5A 2HE4A 2AWXA 2IWNA 2DLUA 2LOBA 1TE0A 2OQSA 1UEWA 2X7ZA 1KWAA 1N6EA 3PV4A 1W9OA 2EAQA 3L4FD 4JOHA 1G9OA 4NMQA 3MH4A 5E11A 3KHFA 1UJUA 4K75A 1NTEA 2YUYA 2KL1A 1OBXA 1VAEA 3OTPA 3EGGC 4FLNA 2LUIA 5FHTA 2JINA 4NMOA 3WKLA 2PKUA 5GLJA 2AINA 1WFGA 2M0VA 3PV5A 1LCYA 1OZIA 5ILBA 1UEQA 1PDRA 1GQ5A 1N6FA 1X8SA 1WFVA 3LNYA 1SOZA 3SHUA 1OBYA 2JOAA 2VSPA 2JSNA 4REYA 2L4TA 2I0LA 1WIFA 3TSZA 4KFWA 2G5MB 3DJAA 3HVQC 4UU6A 1QAUA 4R2ZA 1UITA 1M5ZA 3HPMA 2KAWA 1GM1A 2MHOA 4N6XA 2YTWA 1UEPA 1K32A 4NXRA 1T2MA 2R3YA 1MC7A 2YT7A 2KBSA 1Q7XA 2RCZA 2Q3GA 5HETA 2KOMA 3KZDA 5HEDA 5HJ1A 3MH6A 3CBYA 4KFVA 1GQ4A 2OPGA 2PA1A 2EDVA 1Z86A 3VQGA 5HFFA 4YDPA 2D8IA 5EZ0A 3SOEA 2PDZA 2DAZA 2KJPA 3DJ1A 2OSGA 3JXTA 2EHRA
chains in the Genus database with same CATH topology
3OU0A 1N7FA 3KZEA 5EYZA 1IU0A 1UFXA 2I4SA 1UJDA 2VRFA 4JOEA 1W9EA 4L8NA 5E1YA 1U3BA 2DB5A 3GDVA 3CBZA 2AWUA 2EXGA 4H11A 2CSJA 3R69A 3NFLA 5I7ZA 2KA9A 2VWRA 4NXPA 1FC9A 3PV2A 2BYGA 3SFJA 3TMHA 3CYYA 1WJLA 1RZXA 3DIWA 1RGRA 3I18A 2YT8A 2I1NA 1V5QA 3BPUA 2W7RA 2IWQA 1WF8A 3SUZA 5HF1A 3R0HA 2OGPA 4Q3HA 5HFCA 4Q6SA 2QBWA 1ZOKA 4PQWA 5HEBA 4E3BA 1VCWA 3ID1A 2K20A 2V1WA 3LNXA 1U38A 4OAJA 4Q2QA 4F8KA 4Q2NA 2GEFA 5DTHA 2DKRA 4EDJA 3GDUA 1X5QA 2KJDA 4XHVA 1Q3PA 1Y8TA 2HGAA 3GJ9A 3CS0A 2V90A 1UM1A 4OEPA 2OMJA 4NXQA 3ZRTA 1TQ3A 4Q2PA 1X5RA 4WYTA 2AWWA 2EJYA 4Z33A 3QJMA 4NMTA 3GSLA 2EGKA 2YUBA 4NNMA 2EEHA 1VJ6A 3GCOA 5D13A 5FB8C 2KOHA 2H2CA 2E7KA 3GGEA 4JOPA 3B76A 1X6DA 1B8QA 3E17A 1X5NA 3PS4A 1W9QA 4IC6A 1N6DA 3NFKA 5HDYA 3QIKA 1WHDA 5HFEA 2D90A 2O2TA 2M0UA 2LA8A 1QAVB 1X45A 2PKTA 2EDZA 3SHWA 4RI0A 4HOPB 3I4WA 4P0CA 5F3XA 1RGWA 1IHJA 1TP5A 4JOGA 1TP3A 1WG6A 3GABA 1FC7A 3PDVA 3TSVA 2EDPA 4JL7A 1BFEA 1R6JA 1Z87A 1WF7A 2EEJA 2W4FA 2VSVA 1OBZA 3RLEA 1WH1A 2JXOA 1WI2A 1WHAA 2KV8A 4NMSA 2M0ZA 2DC2A 2I6VA 2P3WA 3RL8A 1Q3OA 2R4HA 3KDKA 1L6OA 4K78A 1UHPA 3HPKA 4GVDA 1X9ZA 3NCVA 4FGMA 2DM8A 4WYUA 2PZDA 3O46A 1KY9A 1UM7A 5G1EA 2H2BA 1MFGA 2KPKA 5HFBA 3ID4A 3GCNA 4JOKA 2EV8A 2M10A 4JOJA 2QKUA 2VPHA 2LC7A 2KJKA 4GVCA 4JJ3A 2M3MA 1D5GA 3PDZA 1UEZA 2UZCA 3DJ3A 3ID2A 4NMRA 3K50A 2DJTA 2KPLA 5F67A 1N7EA 4E35A 1N99A 1V62A 1P1EA 2KQFA 3GDSA 2L97A 2KYLA 3EGHC 4JORA 3FY5A 1WI4A 3CC0A 2JWEA 2EGNA 2JILA 3QJNA 3QE1A 1FC6A 3K82A 1QAVA 2KOJA 1QLCA 2KRGA 2EGOA 3STJA 4NMVA 1V6BA 4HOPA 4JJ0A 1VA8A 2F0AA 4MPAA 2LC6A 2EEGA 5A2PA 4P2AB 5HFDA 4YYXA 1RY4A 3QDOA 2G2LA 5E22A 2QKTA 5HEYA 1BE9A 1V1TA 3O5NA 2D92A 3RL7A 5G1DA 2F5YA 2QT5A 2REYA 2Z9IA 5B6LA 4Q2OA 2JIKA 5IL9A 2ZPMA 2EEIA 4K6YA 3VQFA 2WL7A 2DLSA 2OZFA 5GNDA 3TSWA 4E34A 3ID3A 1U37A 2ENOA 2FNEA 1I16A 4UU5A 4Z8JA 1KEFA 2OS6A 3DORA 2H3MA 2H3LA 2I04A 4OEOA 3CH8A 5E21A 2CS5A 1N7TA 4K72A 4JOFA 1UJVA 1ZUBA 5HF4A 1P1DA 2DMZA 1Y7NA 2FN5A 5E6PB 2MX6A 1FCFA 4G69A 1XZ9A 4GHNA 2RRMA 2OCSA 3K1RA 3QGLA 2Q9VA 1U39A 2I0IA 2Z17A 1NF3C 3WKMA 4LMMA 2IWOA 2GZVA 3I1EA 1VB7A 3KDGA 5B42A 2L4SA 3QO6A 2QKVA 2JREA 2K1ZA 2ZPLA 1YBOA 4K76A 4NNLA 5H3JA 1IU2A 2HE2A 2FCFA 4AMHA 1V5LA 3NGHA 2PNTA 4O06A 1I92A 2FE5A 2QG1A 3R68A 2KG2A 3CBXA 1SOTA 2M0TA 1MFLA 4Q6HA 5JXBA 4NMPA 3MH7A 1UF1A 3AXAA 2CSSA 2IWPA 2VZ5A 2HE4A 2AWXA 2IWNA 2DLUA 2LOBA 1TE0A 2OQSA 1UEWA 2X7ZA 1KWAA 1N6EA 3PV4A 1W9OA 2EAQA 3L4FD 4JOHA 1G9OA 4NMQA 3MH4A 5E11A 3KHFA 1UJUA 4K75A 1NTEA 2YUYA 2KL1A 1OBXA 1VAEA 3OTPA 3EGGC 4FLNA 2LUIA 5FHTA 2JINA 4NMOA 3WKLA 2PKUA 5GLJA 2AINA 1WFGA 2M0VA 3PV5A 1LCYA 1OZIA 5ILBA 1UEQA 1PDRA 1GQ5A 1N6FA 1X8SA 1WFVA 3LNYA 1SOZA 3SHUA 1OBYA 2JOAA 2VSPA 2JSNA 4REYA 2L4TA 2I0LA 1WIFA 3TSZA 4KFWA 2G5MB 3DJAA 3HVQC 4UU6A 1QAUA 4R2ZA 1UITA 1M5ZA 3HPMA 2KAWA 1GM1A 2MHOA 4N6XA 2YTWA 1UEPA 1K32A 4NXRA 1T2MA 2R3YA 1MC7A 2YT7A 2KBSA 1Q7XA 2RCZA 2Q3GA 5HETA 2KOMA 3KZDA 5HEDA 5HJ1A 3MH6A 3CBYA 4KFVA 1GQ4A 2OPGA 2PA1A 2EDVA 1Z86A 3VQGA 5HFFA 4YDPA 2D8IA 5EZ0A 3SOEA 2PDZA 2DAZA 2KJPA 3DJ1A 2OSGA 3JXTA 2EHRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OU0 A;  1N7F A;  3KZE A;  5EYZ A;  1IU0 A;  1UFX A;  2I4S A;  1UJD A;  2VRF A;  4JOE A;  1W9E A;  4L8N A;  5E1Y A;  1U3B A;  2DB5 A;  3GDV A;  3CBZ A;  2AWU A;  2EXG A;  4H11 A;  2CSJ A;  3R69 A;  3NFL A;  5I7Z A;  2KA9 A;  2VWR A;  4NXP A;  1FC9 A;  3PV2 A;  2BYG A;  3SFJ A;  3TMH A;  3CYY A;  1WJL A;  1RZX A;  3DIW A;  1RGR A;  3I18 A;  2YT8 A;  2I1N A;  1V5Q A;  3BPU A;  2W7R A;  2IWQ A;  1WF8 A;  3SUZ A;  5HF1 A;  3R0H A;  2OGP A;  4Q3H A;  5HFC A;  4Q6S A;  2QBW A;  1ZOK A;  4PQW A;  5HEB A;  4E3B A;  1VCW A;  3ID1 A;  2K20 A;  2V1W A;  3LNX A;  1U38 A;  4OAJ A;  4Q2Q A;  4F8K A;  4Q2N A;  5DTH A;  2DKR A;  4EDJ A;  3GDU A;  1X5Q A;  2KJD A;  4XHV A;  1Q3P A;  1Y8T A;  2HGA A;  3GJ9 A;  3CS0 A;  2V90 A;  1UM1 A;  4OEP A;  2OMJ A;  4NXQ A;  3ZRT A;  1TQ3 A;  4Q2P A;  1X5R A;  4WYT A;  2AWW A;  2EJY A;  4Z33 A;  3QJM A;  4NMT A;  3GSL A;  2EGK A;  2YUB A;  4NNM A;  2EEH A;  1VJ6 A;  3GCO A;  5D13 A;  5FB8 C;  2KOH A;  2H2C A;  2E7K A;  3GGE A;  4JOP A;  3B76 A;  1X6D A;  1B8Q A;  3E17 A;  1X5N A;  3PS4 A;  1W9Q A;  4IC6 A;  1N6D A;  3NFK A;  5HDY A;  3QIK A;  1WHD A;  5HFE A;  2D90 A;  2O2T A;  2M0U A;  2LA8 A;  1QAV B;  1X45 A;  2PKT A;  2EDZ A;  3SHW A;  4RI0 A;  4HOP B;  3I4W A;  4P0C A;  5F3X A;  1RGW A;  1IHJ A;  1TP5 A;  4JOG A;  1TP3 A;  1WG6 A;  1FC7 A;  3PDV A;  3TSV A;  2EDP A;  4JL7 A;  1BFE A;  1R6J A;  1Z87 A;  1WF7 A;  2EEJ A;  2W4F A;  2VSV A;  1OBZ A;  3RLE A;  1WH1 A;  2JXO A;  1WI2 A;  1WHA A;  2KV8 A;  4NMS A;  2M0Z A;  2DC2 A;  2I6V A;  2P3W A;  3RL8 A;  1Q3O A;  2R4H A;  1L6O A;  4K78 A;  1UHP A;  3HPK A;  4GVD A;  4FGM A;  2DM8 A;  4WYU A;  2PZD A;  3O46 A;  1KY9 A;  1UM7 A;  5G1E A;  2H2B A;  1MFG A;  2KPK A;  5HFB A;  3ID4 A;  3GCN A;  4JOK A;  2EV8 A;  2M10 A;  4JOJ A;  2QKU A;  2VPH A;  2LC7 A;  2KJK A;  4GVC A;  2M3M A;  1D5G A;  3PDZ A;  1UEZ A;  2UZC A;  3DJ3 A;  3ID2 A;  4NMR A;  3K50 A;  2DJT A;  2KPL A;  5F67 A;  1N7E A;  4E35 A;  1N99 A;  1V62 A;  1P1E A;  2KQF A;  3GDS A;  2L97 A;  2KYL A;  3EGH C;  4JOR A;  3FY5 A;  1WI4 A;  3CC0 A;  2JWE A;  2EGN A;  2JIL A;  3QJN A;  3QE1 A;  1FC6 A;  3K82 A;  1QAV A;  2KOJ A;  1QLC A;  2KRG A;  2EGO A;  3STJ A;  4NMV A;  1V6B A;  4HOP A;  1VA8 A;  2F0A A;  4MPA A;  2LC6 A;  2EEG A;  5A2P A;  4P2A B;  5HFD A;  4YYX A;  1RY4 A;  3QDO A;  2G2L A;  5E22 A;  2QKT A;  5HEY A;  1BE9 A;  1V1T A;  3O5N A;  2D92 A;  3RL7 A;  5G1D A;  2F5Y A;  2QT5 A;  2REY A;  2Z9I A;  5B6L A;  4Q2O A;  2JIK A;  2ZPM A;  2EEI A;  4K6Y A;  3VQF A;  2WL7 A;  2DLS A;  2OZF A;  5GND A;  3TSW A;  4E34 A;  3ID3 A;  1U37 A;  2ENO A;  2FNE A;  1I16 A;  4UU5 A;  4Z8J A;  1KEF A;  2OS6 A;  3DOR A;  2H3M A;  2H3L A;  2I04 A;  4OEO A;  3CH8 A;  5E21 A;  2CS5 A;  1N7T A;  4K72 A;  4JOF A;  1UJV A;  1ZUB A;  5HF4 A;  1P1D A;  2DMZ A;  1Y7N A;  2FN5 A;  5E6P B;  2MX6 A;  1FCF A;  4G69 A;  1XZ9 A;  4GHN A;  2RRM A;  2OCS A;  3K1R A;  3QGL A;  2Q9V A;  1U39 A;  2I0I A;  2Z17 A;  1NF3 C;  3WKM A;  4LMM A;  2IWO A;  2GZV A;  3I1E A;  1VB7 A;  2L4S A;  3QO6 A;  2QKV A;  2JRE A;  2K1Z A;  2ZPL A;  1YBO A;  4K76 A;  4NNL A;  5H3J A;  1IU2 A;  2HE2 A;  2FCF A;  4AMH A;  1V5L A;  3NGH A;  2PNT A;  4O06 A;  1I92 A;  2FE5 A;  2QG1 A;  3R68 A;  2KG2 A;  3CBX A;  1SOT A;  2M0T A;  1MFL A;  4Q6H A;  5JXB A;  4NMP A;  3MH7 A;  1UF1 A;  3AXA A;  2CSS A;  2IWP A;  2VZ5 A;  2HE4 A;  2AWX A;  2IWN A;  2DLU A;  2LOB A;  1TE0 A;  2OQS A;  1UEW A;  2X7Z A;  1KWA A;  1N6E A;  3PV4 A;  1W9O A;  2EAQ A;  3L4F D;  4JOH A;  1G9O A;  4NMQ A;  3MH4 A;  5E11 A;  3KHF A;  1UJU A;  4K75 A;  1NTE A;  2YUY A;  2KL1 A;  1OBX A;  1VAE A;  3OTP A;  3EGG C;  2LUI A;  5FHT A;  2JIN A;  4NMO A;  3WKL A;  2PKU A;  5GLJ A;  2AIN A;  1WFG A;  2M0V A;  3PV5 A;  1LCY A;  1OZI A;  1UEQ A;  1PDR A;  1GQ5 A;  1N6F A;  1X8S A;  1WFV A;  3LNY A;  1SOZ A;  3SHU A;  1OBY A;  2JOA A;  2VSP A;  4REY A;  2L4T A;  2I0L A;  1WIF A;  3TSZ A;  4KFW A;  2G5M B;  3DJA A;  3HVQ C;  4UU6 A;  1QAU A;  4R2Z A;  1UIT A;  1M5Z A;  3HPM A;  2KAW A;  1GM1 A;  2MHO A;  4N6X A;  2YTW A;  1UEP A;  1K32 A;  4NXR A;  1T2M A;  2R3Y A;  1MC7 A;  2YT7 A;  2KBS A;  1Q7X A;  2RCZ A;  2Q3G A;  5HET A;  2KOM A;  3KZD A;  5HED A;  5HJ1 A;  3MH6 A;  3CBY A;  4KFV A;  1GQ4 A;  2OPG A;  2PA1 A;  2EDV A;  1Z86 A;  3VQG A;  5HFF A;  4YDP A;  2D8I A;  5EZ0 A;  3SOE A;  2PDZ A;  2DAZ A;  2KJP A;  3DJ1 A;  2OSG A;  3JXT A;  2EHR A; 
#chains in the Genus database with same CATH topology
 3OU0 A;  1N7F A;  3KZE A;  5EYZ A;  1IU0 A;  1UFX A;  2I4S A;  1UJD A;  2VRF A;  4JOE A;  1W9E A;  4L8N A;  5E1Y A;  1U3B A;  2DB5 A;  3GDV A;  3CBZ A;  2AWU A;  2EXG A;  4H11 A;  2CSJ A;  3R69 A;  3NFL A;  5I7Z A;  2KA9 A;  2VWR A;  4NXP A;  1FC9 A;  3PV2 A;  2BYG A;  3SFJ A;  3TMH A;  3CYY A;  1WJL A;  1RZX A;  3DIW A;  1RGR A;  3I18 A;  2YT8 A;  2I1N A;  1V5Q A;  3BPU A;  2W7R A;  2IWQ A;  1WF8 A;  3SUZ A;  5HF1 A;  3R0H A;  2OGP A;  4Q3H A;  5HFC A;  4Q6S A;  2QBW A;  1ZOK A;  4PQW A;  5HEB A;  4E3B A;  1VCW A;  3ID1 A;  2K20 A;  2V1W A;  3LNX A;  1U38 A;  4OAJ A;  4Q2Q A;  4F8K A;  4Q2N A;  2GEF A;  5DTH A;  2DKR A;  4EDJ A;  3GDU A;  1X5Q A;  2KJD A;  4XHV A;  1Q3P A;  1Y8T A;  2HGA A;  3GJ9 A;  3CS0 A;  2V90 A;  1UM1 A;  4OEP A;  2OMJ A;  4NXQ A;  3ZRT A;  1TQ3 A;  4Q2P A;  1X5R A;  4WYT A;  2AWW A;  2EJY A;  4Z33 A;  3QJM A;  4NMT A;  3GSL A;  2EGK A;  2YUB A;  4NNM A;  2EEH A;  1VJ6 A;  3GCO A;  5D13 A;  5FB8 C;  2KOH A;  2H2C A;  2E7K A;  3GGE A;  4JOP A;  3B76 A;  1X6D A;  1B8Q A;  3E17 A;  1X5N A;  3PS4 A;  1W9Q A;  4IC6 A;  1N6D A;  3NFK A;  5HDY A;  3QIK A;  1WHD A;  5HFE A;  2D90 A;  2O2T A;  2M0U A;  2LA8 A;  1QAV B;  1X45 A;  2PKT A;  2EDZ A;  3SHW A;  4RI0 A;  4HOP B;  3I4W A;  4P0C A;  5F3X A;  1RGW A;  1IHJ A;  1TP5 A;  4JOG A;  1TP3 A;  1WG6 A;  3GAB A;  1FC7 A;  3PDV A;  3TSV A;  2EDP A;  4JL7 A;  1BFE A;  1R6J A;  1Z87 A;  1WF7 A;  2EEJ A;  2W4F A;  2VSV A;  1OBZ A;  3RLE A;  1WH1 A;  2JXO A;  1WI2 A;  1WHA A;  2KV8 A;  4NMS A;  2M0Z A;  2DC2 A;  2I6V A;  2P3W A;  3RL8 A;  1Q3O A;  2R4H A;  3KDK A;  1L6O A;  4K78 A;  1UHP A;  3HPK A;  4GVD A;  1X9Z A;  3NCV A;  4FGM A;  2DM8 A;  4WYU A;  2PZD A;  3O46 A;  1KY9 A;  1UM7 A;  5G1E A;  2H2B A;  1MFG A;  2KPK A;  5HFB A;  3ID4 A;  3GCN A;  4JOK A;  2EV8 A;  2M10 A;  4JOJ A;  2QKU A;  2VPH A;  2LC7 A;  2KJK A;  4GVC A;  4JJ3 A;  2M3M A;  1D5G A;  3PDZ A;  1UEZ A;  2UZC A;  3DJ3 A;  3ID2 A;  4NMR A;  3K50 A;  2DJT A;  2KPL A;  5F67 A;  1N7E A;  4E35 A;  1N99 A;  1V62 A;  1P1E A;  2KQF A;  3GDS A;  2L97 A;  2KYL A;  3EGH C;  4JOR A;  3FY5 A;  1WI4 A;  3CC0 A;  2JWE A;  2EGN A;  2JIL A;  3QJN A;  3QE1 A;  1FC6 A;  3K82 A;  1QAV A;  2KOJ A;  1QLC A;  2KRG A;  2EGO A;  3STJ A;  4NMV A;  1V6B A;  4HOP A;  4JJ0 A;  1VA8 A;  2F0A A;  4MPA A;  2LC6 A;  2EEG A;  5A2P A;  4P2A B;  5HFD A;  4YYX A;  1RY4 A;  3QDO A;  2G2L A;  5E22 A;  2QKT A;  5HEY A;  1BE9 A;  1V1T A;  3O5N A;  2D92 A;  3RL7 A;  5G1D A;  2F5Y A;  2QT5 A;  2REY A;  2Z9I A;  5B6L A;  4Q2O A;  2JIK A;  5IL9 A;  2ZPM A;  2EEI A;  4K6Y A;  3VQF A;  2WL7 A;  2DLS A;  2OZF A;  5GND A;  3TSW A;  4E34 A;  3ID3 A;  1U37 A;  2ENO A;  2FNE A;  1I16 A;  4UU5 A;  4Z8J A;  1KEF A;  2OS6 A;  3DOR A;  2H3M A;  2H3L A;  2I04 A;  4OEO A;  3CH8 A;  5E21 A;  2CS5 A;  1N7T A;  4K72 A;  4JOF A;  1UJV A;  1ZUB A;  5HF4 A;  1P1D A;  2DMZ A;  1Y7N A;  2FN5 A;  5E6P B;  2MX6 A;  1FCF A;  4G69 A;  1XZ9 A;  4GHN A;  2RRM A;  2OCS A;  3K1R A;  3QGL A;  2Q9V A;  1U39 A;  2I0I A;  2Z17 A;  1NF3 C;  3WKM A;  4LMM A;  2IWO A;  2GZV A;  3I1E A;  1VB7 A;  3KDG A;  5B42 A;  2L4S A;  3QO6 A;  2QKV A;  2JRE A;  2K1Z A;  2ZPL A;  1YBO A;  4K76 A;  4NNL A;  5H3J A;  1IU2 A;  2HE2 A;  2FCF A;  4AMH A;  1V5L A;  3NGH A;  2PNT A;  4O06 A;  1I92 A;  2FE5 A;  2QG1 A;  3R68 A;  2KG2 A;  3CBX A;  1SOT A;  2M0T A;  1MFL A;  4Q6H A;  5JXB A;  4NMP A;  3MH7 A;  1UF1 A;  3AXA A;  2CSS A;  2IWP A;  2VZ5 A;  2HE4 A;  2AWX A;  2IWN A;  2DLU A;  2LOB A;  1TE0 A;  2OQS A;  1UEW A;  2X7Z A;  1KWA A;  1N6E A;  3PV4 A;  1W9O A;  2EAQ A;  3L4F D;  4JOH A;  1G9O A;  4NMQ A;  3MH4 A;  5E11 A;  3KHF A;  1UJU A;  4K75 A;  1NTE A;  2YUY A;  2KL1 A;  1OBX A;  1VAE A;  3OTP A;  3EGG C;  4FLN A;  2LUI A;  5FHT A;  2JIN A;  4NMO A;  3WKL A;  2PKU A;  5GLJ A;  2AIN A;  1WFG A;  2M0V A;  3PV5 A;  1LCY A;  1OZI A;  5ILB A;  1UEQ A;  1PDR A;  1GQ5 A;  1N6F A;  1X8S A;  1WFV A;  3LNY A;  1SOZ A;  3SHU A;  1OBY A;  2JOA A;  2VSP A;  2JSN A;  4REY A;  2L4T A;  2I0L A;  1WIF A;  3TSZ A;  4KFW A;  2G5M B;  3DJA A;  3HVQ C;  4UU6 A;  1QAU A;  4R2Z A;  1UIT A;  1M5Z A;  3HPM A;  2KAW A;  1GM1 A;  2MHO A;  4N6X A;  2YTW A;  1UEP A;  1K32 A;  4NXR A;  1T2M A;  2R3Y A;  1MC7 A;  2YT7 A;  2KBS A;  1Q7X A;  2RCZ A;  2Q3G A;  5HET A;  2KOM A;  3KZD A;  5HED A;  5HJ1 A;  3MH6 A;  3CBY A;  4KFV A;  1GQ4 A;  2OPG A;  2PA1 A;  2EDV A;  1Z86 A;  3VQG A;  5HFF A;  4YDP A;  2D8I A;  5EZ0 A;  3SOE A;  2PDZ A;  2DAZ A;  2KJP A;  3DJ1 A;  2OSG A;  3JXT A;  2EHR A; 
#chains in the Genus database with same CATH homology
 3OU0 A;  1N7F A;  3KZE A;  5EYZ A;  1IU0 A;  1UFX A;  2I4S A;  1UJD A;  2VRF A;  4JOE A;  1W9E A;  4L8N A;  5E1Y A;  1U3B A;  2DB5 A;  3GDV A;  3CBZ A;  2AWU A;  2EXG A;  4H11 A;  2CSJ A;  3R69 A;  3NFL A;  5I7Z A;  2KA9 A;  2VWR A;  4NXP A;  1FC9 A;  3PV2 A;  2BYG A;  3SFJ A;  3TMH A;  3CYY A;  1WJL A;  1RZX A;  3DIW A;  1RGR A;  3I18 A;  2YT8 A;  2I1N A;  1V5Q A;  3BPU A;  2W7R A;  2IWQ A;  1WF8 A;  3SUZ A;  5HF1 A;  3R0H A;  2OGP A;  4Q3H A;  5HFC A;  4Q6S A;  2QBW A;  1ZOK A;  4PQW A;  5HEB A;  4E3B A;  1VCW A;  3ID1 A;  2K20 A;  2V1W A;  3LNX A;  1U38 A;  4OAJ A;  4Q2Q A;  4F8K A;  4Q2N A;  2GEF A;  5DTH A;  2DKR A;  4EDJ A;  3GDU A;  1X5Q A;  2KJD A;  4XHV A;  1Q3P A;  1Y8T A;  2HGA A;  3GJ9 A;  3CS0 A;  2V90 A;  1UM1 A;  4OEP A;  2OMJ A;  4NXQ A;  3ZRT A;  1TQ3 A;  4Q2P A;  1X5R A;  4WYT A;  2AWW A;  2EJY A;  4Z33 A;  3QJM A;  4NMT A;  3GSL A;  2EGK A;  2YUB A;  4NNM A;  2EEH A;  1VJ6 A;  3GCO A;  5D13 A;  5FB8 C;  2KOH A;  2H2C A;  2E7K A;  3GGE A;  4JOP A;  3B76 A;  1X6D A;  1B8Q A;  3E17 A;  1X5N A;  3PS4 A;  1W9Q A;  4IC6 A;  1N6D A;  3NFK A;  5HDY A;  3QIK A;  1WHD A;  5HFE A;  2D90 A;  2O2T A;  2M0U A;  2LA8 A;  1QAV B;  1X45 A;  2PKT A;  2EDZ A;  3SHW A;  4RI0 A;  4HOP B;  3I4W A;  4P0C A;  5F3X A;  1RGW A;  1IHJ A;  1TP5 A;  4JOG A;  1TP3 A;  1WG6 A;  3GAB A;  1FC7 A;  3PDV A;  3TSV A;  2EDP A;  4JL7 A;  1BFE A;  1R6J A;  1Z87 A;  1WF7 A;  2EEJ A;  2W4F A;  2VSV A;  1OBZ A;  3RLE A;  1WH1 A;  2JXO A;  1WI2 A;  1WHA A;  2KV8 A;  4NMS A;  2M0Z A;  2DC2 A;  2I6V A;  2P3W A;  3RL8 A;  1Q3O A;  2R4H A;  3KDK A;  1L6O A;  4K78 A;  1UHP A;  3HPK A;  4GVD A;  1X9Z A;  3NCV A;  4FGM A;  2DM8 A;  4WYU A;  2PZD A;  3O46 A;  1KY9 A;  1UM7 A;  5G1E A;  2H2B A;  1MFG A;  2KPK A;  5HFB A;  3ID4 A;  3GCN A;  4JOK A;  2EV8 A;  2M10 A;  4JOJ A;  2QKU A;  2VPH A;  2LC7 A;  2KJK A;  4GVC A;  4JJ3 A;  2M3M A;  1D5G A;  3PDZ A;  1UEZ A;  2UZC A;  3DJ3 A;  3ID2 A;  4NMR A;  3K50 A;  2DJT A;  2KPL A;  5F67 A;  1N7E A;  4E35 A;  1N99 A;  1V62 A;  1P1E A;  2KQF A;  3GDS A;  2L97 A;  2KYL A;  3EGH C;  4JOR A;  3FY5 A;  1WI4 A;  3CC0 A;  2JWE A;  2EGN A;  2JIL A;  3QJN A;  3QE1 A;  1FC6 A;  3K82 A;  1QAV A;  2KOJ A;  1QLC A;  2KRG A;  2EGO A;  3STJ A;  4NMV A;  1V6B A;  4HOP A;  4JJ0 A;  1VA8 A;  2F0A A;  4MPA A;  2LC6 A;  2EEG A;  5A2P A;  4P2A B;  5HFD A;  4YYX A;  1RY4 A;  3QDO A;  2G2L A;  5E22 A;  2QKT A;  5HEY A;  1BE9 A;  1V1T A;  3O5N A;  2D92 A;  3RL7 A;  5G1D A;  2F5Y A;  2QT5 A;  2REY A;  2Z9I A;  5B6L A;  4Q2O A;  2JIK A;  5IL9 A;  2ZPM A;  2EEI A;  4K6Y A;  3VQF A;  2WL7 A;  2DLS A;  2OZF A;  5GND A;  3TSW A;  4E34 A;  3ID3 A;  1U37 A;  2ENO A;  2FNE A;  1I16 A;  4UU5 A;  4Z8J A;  1KEF A;  2OS6 A;  3DOR A;  2H3M A;  2H3L A;  2I04 A;  4OEO A;  3CH8 A;  5E21 A;  2CS5 A;  1N7T A;  4K72 A;  4JOF A;  1UJV A;  1ZUB A;  5HF4 A;  1P1D A;  2DMZ A;  1Y7N A;  2FN5 A;  5E6P B;  2MX6 A;  1FCF A;  4G69 A;  1XZ9 A;  4GHN A;  2RRM A;  2OCS A;  3K1R A;  3QGL A;  2Q9V A;  1U39 A;  2I0I A;  2Z17 A;  1NF3 C;  3WKM A;  4LMM A;  2IWO A;  2GZV A;  3I1E A;  1VB7 A;  3KDG A;  5B42 A;  2L4S A;  3QO6 A;  2QKV A;  2JRE A;  2K1Z A;  2ZPL A;  1YBO A;  4K76 A;  4NNL A;  5H3J A;  1IU2 A;  2HE2 A;  2FCF A;  4AMH A;  1V5L A;  3NGH A;  2PNT A;  4O06 A;  1I92 A;  2FE5 A;  2QG1 A;  3R68 A;  2KG2 A;  3CBX A;  1SOT A;  2M0T A;  1MFL A;  4Q6H A;  5JXB A;  4NMP A;  3MH7 A;  1UF1 A;  3AXA A;  2CSS A;  2IWP A;  2VZ5 A;  2HE4 A;  2AWX A;  2IWN A;  2DLU A;  2LOB A;  1TE0 A;  2OQS A;  1UEW A;  2X7Z A;  1KWA A;  1N6E A;  3PV4 A;  1W9O A;  2EAQ A;  3L4F D;  4JOH A;  1G9O A;  4NMQ A;  3MH4 A;  5E11 A;  3KHF A;  1UJU A;  4K75 A;  1NTE A;  2YUY A;  2KL1 A;  1OBX A;  1VAE A;  3OTP A;  3EGG C;  4FLN A;  2LUI A;  5FHT A;  2JIN A;  4NMO A;  3WKL A;  2PKU A;  5GLJ A;  2AIN A;  1WFG A;  2M0V A;  3PV5 A;  1LCY A;  1OZI A;  5ILB A;  1UEQ A;  1PDR A;  1GQ5 A;  1N6F A;  1X8S A;  1WFV A;  3LNY A;  1SOZ A;  3SHU A;  1OBY A;  2JOA A;  2VSP A;  2JSN A;  4REY A;  2L4T A;  2I0L A;  1WIF A;  3TSZ A;  4KFW A;  2G5M B;  3DJA A;  3HVQ C;  4UU6 A;  1QAU A;  4R2Z A;  1UIT A;  1M5Z A;  3HPM A;  2KAW A;  1GM1 A;  2MHO A;  4N6X A;  2YTW A;  1UEP A;  1K32 A;  4NXR A;  1T2M A;  2R3Y A;  1MC7 A;  2YT7 A;  2KBS A;  1Q7X A;  2RCZ A;  2Q3G A;  5HET A;  2KOM A;  3KZD A;  5HED A;  5HJ1 A;  3MH6 A;  3CBY A;  4KFV A;  1GQ4 A;  2OPG A;  2PA1 A;  2EDV A;  1Z86 A;  3VQG A;  5HFF A;  4YDP A;  2D8I A;  5EZ0 A;  3SOE A;  2PDZ A;  2DAZ A;  2KJP A;  3DJ1 A;  2OSG A;  3JXT A;  2EHR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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