4HOPA

Crystal structure of the computationally designed nnos-syntrophin complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
87
structure length
87
Chain Sequence
SLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATFDEAVQALKKTGKEVVLEVKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition.
pubmed doi rcsb
molecule tags Membrane protein/oxidoreductase
source organism Mus musculus
molecule keywords Alpha-1-syntrophin
total genus 20
structure length 87
sequence length 87
chains with identical sequence C, E
ec nomenclature
pdb deposition date 2012-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4hopA00
2CSSA 2Z9IA 2WL7A 1P1EA 3TSWA 3NFKA 2YTWA 2JREA 2K1ZA 1L6OA 2M0TA 2IWPA 3ID2A 3CH8A 1Z86A 1WF8A 3L4FD 1WIFA 3QIKA 3CYYA 3NFLA 4JL7A 2H2CA 2LC7A 4F8KA 5EYZA 4OEPA 5B6LA 3TSZA 2EEIA 2M0ZA 3QJNA 4IC6A 5F67A 4NMTA 1U38A 2VSPA 4OAJA 2YT7A 2AWWA 1UJUA 2QKTA 1BFEA 2EHRA 3QDOA 1QAVB 1UJVA 3TMHA 2VSVA 1YBOA 2KQFA 5HEYA 2JINA 2E7KA 2M10A 3GJ9A 1V62A 5A2PA 1WHDA 4NXPA 4H11A 1RZXA 1V6BA 5HETA 4NXQA 3JXTA 3AXAA 4PQWA 4JOHA 4N6XA 2QKVA 3EGHC 1UM1A 4Q2QA 1FC7A 4JOPA 1TQ3A 1OZIA 1UM7A 2I04A 1Z87A 1W9EA 5G1DA 3HVQC 2KJDA 1WG6A 2HGAA 2VPHA 3MH4A 3ID4A 2DC2A 1NTEA 2JILA 2W4FA 4NMRA 3SHUA 2EGKA 2KYLA 2AINA 5HFDA 4NNLA 3EGGC 4K76A 5E21A 1UEPA 2DLUA 2EDVA 1X6DA 2LUIA 5GNDA 2YUBA 2ENOA 4K78A 4G69A 2MX6A 1X5NA 3R0HA 2F0AA 4K6YA 2L4TA 1WFVA 2MHOA 2CS5A 3DIWA 2I6VA 1R6JA 3LNXA 4Z33A 2ZPLA 3K50A 4LMMA 2KRGA 2OPGA 1WF7A 2GZVA 2I0IA 3I4WA 3CC0A 2KOMA 2G5MB 2QBWA 4L8NA 3MH6A 1TP3A 3KZEA 2DLSA 2YT8A 1X5RA 4K72A 5HEDA 2EXGA 1SOZA 1BE9A 2IWQA 1V1TA 1NF3C 3QE1A 3CBYA 1UITA 2KA9A 2YUYA 3PS4A 2Q9VA 2VZ5A 2D90A 5DTHA 2JXOA 2EV8A 3GCOA 4NMPA 2LC6A 1X8SA 3STJA 2EAQA 2OS6A 1UEWA 4UU5A 3CBZA 2UZCA 1SOTA 3HPMA 4HOPA 1I16A 1UEQA 3ZRTA 1N6DA 2JWEA 1VA8A 3TSVA 3QGLA 1N7FA 3K1RA 1QAUA 1UEZA 5E11A 3GSLA 1Q3OA 2RCZA 3ID1A 5D13A 1T2MA 1WJLA 1LCYA 3DJ1A 2DAZA 1U37A 3KHFA 2PKUA 3PDVA 4NMQA 2ZPMA 3DJAA 2CSJA 2HE4A 2EGOA 5HJ1A 4O06A 2PKTA 3RLEA 4JORA 3B76A 5H3JA 2PA1A 2I4SA 1UFXA 5JXBA 3FY5A 5GLJA 3RL7A 2KOHA 4RI0A 3NGHA 2EDPA 1N7TA 1FCFA 2O2TA 1FC9A 1M5ZA 2KAWA 1VAEA 3HPKA 2L4SA 5E6PB 4WYUA 1FC6A 2H3LA 2K20A 1PDRA 1TE0A 5HFEA 2I0LA 1G9OA 3R68A 4JOJA 3DJ3A 2EEHA 2R4HA 1XZ9A 4KFWA 2QKUA 3QJMA 4Q2OA 2Z17A 4R2ZA 2PDZA 5HFCA 3PDZA 1VCWA 4Q6HA 2LOBA 1KWAA 1OBYA 3I1EA 3SHWA 1MC7A 1VJ6A 2REYA 5HDYA 2KJPA 1Q7XA 2H3MA 2F5YA 2RRMA 1Y8TA 2KG2A 1N7EA 2DMZA 1MFGA 1Y7NA 2JIKA 1Q3PA 2FN5A 2I1NA 1WI4A 2FCFA 4AMHA 4OEOA 2W7RA 3CBXA 2HE2A 5EZ0A 2L97A 1IU0A 1B8QA 1WI2A 4Q6SA 4E34A 1I92A 3BPUA 2OSGA 5HF1A 3RL8A 2LA8A 2KL1A 5F3XA 1UF1A 1N6FA 4REYA 2EEJA 1GQ5A 1QAVA 3I18A 1U3BA 2H2BA 1WHAA 4WYTA 5FHTA 1WH1A 2IWOA 5E1YA 3GDSA 1ZOKA 2M0UA 1GQ4A 2Q3GA 4GVDA 1UHPA 1WFGA 3VQFA 1IU2A 4JOGA 2PZDA 1X45A 1GM1A 2PNTA 2KJKA 4JOEA 3KZDA 1KY9A 1KEFA 2QG1A 1K32A 3MH7A 4E35A 2VRFA 4NMVA 2M0VA 5HF4A 4EDJA 1N6EA 3OU0A 4NXRA 4NMSA 4UU6A 2DM8A 2AWUA 2EJYA 2D8IA 2DJTA 2KPKA 4GVCA 4K75A 1QLCA 2AWXA 3GGEA 2V1WA 1D5GA 1N99A 4Z8JA 1UJDA 5HFFA 3O5NA 4KFVA 3GDUA 4NMOA 1V5QA 2X7ZA 3OTPA 3GDVA 2G2LA 2V90A 2DB5A 3PV2A 2DKRA 4Q2NA 4GHNA 1RY4A 4HOPB 1OBXA 1TP5A 1IHJA 2OGPA 2IWNA 3LNYA 1V5LA 2KPLA 2R3YA 1P1DA 5HEBA 2BYGA 5E22A 2EDZA 3ID3A 4NNMA 1MFLA 5HFBA 2KV8A 1VB7A 3WKMA 2EEGA 3PV4A 2KOJA 1ZUBA 1W9QA 1RGRA 4JOKA 2VWRA 2D92A 2QT5A 3R69A 4FGMA 5I7ZA 4MPAA 3O46A 5FB8C 3SOEA 5G1EA 3CS0A 2JOAA 1OBZA 4P2AB 1X5QA 3E17A 1RGWA 4Q2PA 1W9OA 2FE5A 4XHVA 2FNEA 4E3BA 2EGNA 3QO6A 4JOFA 3GCNA 4YDPA 3DORA 4P0CA 3K82A 2OMJA 2KBSA 2OCSA 3SUZA 2OQSA 3WKLA 2P3WA 3SFJA 1U39A 3PV5A 4YYXA 4Q3HA 2M3MA 2OZFA 3VQGA
chains in the Genus database with same CATH superfamily
2CSSA 2Z9IA 2WL7A 1P1EA 3TSWA 3NFKA 2YTWA 2JREA 2K1ZA 1L6OA 2M0TA 2IWPA 3ID2A 3CH8A 1Z86A 1WF8A 3L4FD 1WIFA 3QIKA 3CYYA 3NFLA 4JL7A 2H2CA 2LC7A 4F8KA 5EYZA 4OEPA 5B6LA 3TSZA 2EEIA 2M0ZA 3QJNA 4IC6A 5F67A 4NMTA 1U38A 2VSPA 4OAJA 2YT7A 2AWWA 1UJUA 2QKTA 1BFEA 2EHRA 3QDOA 1QAVB 1UJVA 3TMHA 2VSVA 1YBOA 2KQFA 5HEYA 2JINA 2E7KA 2M10A 3GJ9A 1V62A 5A2PA 1WHDA 4NXPA 4H11A 1RZXA 1V6BA 5HETA 4NXQA 3JXTA 3AXAA 4PQWA 4JOHA 4N6XA 2QKVA 3EGHC 1UM1A 4Q2QA 1FC7A 4JOPA 1TQ3A 4JJ3A 1OZIA 1UM7A 2I04A 1Z87A 1W9EA 5G1DA 3HVQC 2KJDA 1WG6A 2HGAA 2VPHA 3GABA 3ID4A 3MH4A 2DC2A 1NTEA 2JILA 2W4FA 4NMRA 3SHUA 2EGKA 2KYLA 2AINA 5HFDA 4NNLA 5ILBA 3EGGC 4K76A 5E21A 1UEPA 2DLUA 2EDVA 1X6DA 2LUIA 5GNDA 2YUBA 2ENOA 4K78A 4G69A 2MX6A 1X5NA 3R0HA 2F0AA 4K6YA 2L4TA 1WFVA 2MHOA 2CS5A 3DIWA 2I6VA 1R6JA 3LNXA 4Z33A 2ZPLA 3K50A 4LMMA 2KRGA 2OPGA 4FLNA 1WF7A 2GZVA 5B42A 2I0IA 3I4WA 3CC0A 2KOMA 2G5MB 2QBWA 4L8NA 3MH6A 1TP3A 3KZEA 2DLSA 2YT8A 1X5RA 4K72A 5HEDA 2EXGA 1SOZA 1BE9A 2IWQA 1V1TA 1NF3C 3QE1A 3CBYA 1UITA 2KA9A 2YUYA 3PS4A 2Q9VA 2VZ5A 2D90A 5DTHA 2JXOA 2EV8A 3GCOA 4NMPA 2LC6A 1X8SA 3STJA 2EAQA 2OS6A 1UEWA 4UU5A 3CBZA 2UZCA 1SOTA 3HPMA 4HOPA 1I16A 1UEQA 3ZRTA 1N6DA 2JWEA 1VA8A 3TSVA 3QGLA 1N7FA 3K1RA 1QAUA 1UEZA 5E11A 3GSLA 1Q3OA 2RCZA 3ID1A 5D13A 1T2MA 1WJLA 1LCYA 3DJ1A 2DAZA 1U37A 3KHFA 2PKUA 3PDVA 4NMQA 2ZPMA 3DJAA 2CSJA 2HE4A 2EGOA 5HJ1A 4O06A 2PKTA 3RLEA 4JORA 3B76A 5H3JA 2PA1A 2I4SA 1UFXA 5JXBA 3FY5A 5GLJA 3RL7A 2KOHA 4RI0A 3NGHA 2EDPA 1N7TA 1FCFA 2O2TA 1FC9A 1M5ZA 2KAWA 1VAEA 3HPKA 2L4SA 5E6PB 1X9ZA 4WYUA 1FC6A 2H3LA 2K20A 1PDRA 1TE0A 5HFEA 2I0LA 1G9OA 3R68A 4JOJA 3DJ3A 2EEHA 2R4HA 1XZ9A 4KFWA 2QKUA 3QJMA 4Q2OA 2Z17A 4R2ZA 2PDZA 5HFCA 3PDZA 1VCWA 4Q6HA 2LOBA 1KWAA 1OBYA 3I1EA 3SHWA 1MC7A 1VJ6A 2REYA 5HDYA 2KJPA 1Q7XA 2H3MA 2F5YA 2RRMA 1Y8TA 2KG2A 1N7EA 2DMZA 1MFGA 1Y7NA 2JIKA 1Q3PA 2FN5A 2GEFA 1WI4A 2I1NA 2FCFA 4AMHA 4OEOA 2W7RA 3CBXA 2HE2A 5EZ0A 2L97A 1IU0A 1B8QA 1WI2A 4Q6SA 4E34A 1I92A 3BPUA 2OSGA 5HF1A 3RL8A 2LA8A 2KL1A 5F3XA 1UF1A 1N6FA 4REYA 2EEJA 1GQ5A 1QAVA 3I18A 1U3BA 2H2BA 1WHAA 4WYTA 5FHTA 1WH1A 2IWOA 5E1YA 3GDSA 1ZOKA 2M0UA 1GQ4A 2Q3GA 4GVDA 1UHPA 1WFGA 3VQFA 1IU2A 4JOGA 2PZDA 1X45A 1GM1A 2PNTA 2KJKA 4JOEA 3KZDA 1KY9A 2JSNA 1KEFA 2QG1A 1K32A 3MH7A 4E35A 2VRFA 4NMVA 2M0VA 5HF4A 4EDJA 1N6EA 3OU0A 4NXRA 4NMSA 4UU6A 2DM8A 2AWUA 2EJYA 2D8IA 2DJTA 2KPKA 4GVCA 4K75A 1QLCA 2AWXA 3GGEA 2V1WA 1D5GA 1N99A 4Z8JA 1UJDA 3NCVA 5HFFA 3O5NA 4KFVA 3GDUA 4NMOA 1V5QA 2X7ZA 3OTPA 3GDVA 5IL9A 2G2LA 2V90A 2DB5A 3PV2A 2DKRA 4Q2NA 4GHNA 1RY4A 4HOPB 1OBXA 1TP5A 1IHJA 2OGPA 2IWNA 3LNYA 1V5LA 2KPLA 2R3YA 1P1DA 3KDKA 5HEBA 2BYGA 5E22A 2EDZA 3ID3A 3KDGA 4NNMA 1MFLA 5HFBA 2KV8A 1VB7A 3WKMA 2EEGA 3PV4A 2KOJA 1ZUBA 1W9QA 1RGRA 4JOKA 2VWRA 2D92A 2QT5A 3R69A 4FGMA 5I7ZA 4MPAA 3O46A 5FB8C 3SOEA 5G1EA 3CS0A 2JOAA 1OBZA 4P2AB 1X5QA 3E17A 1RGWA 4Q2PA 1W9OA 2FE5A 4XHVA 2FNEA 4E3BA 2EGNA 3QO6A 4JOFA 3GCNA 4YDPA 3DORA 4P0CA 3K82A 2OMJA 2KBSA 2OCSA 3SUZA 2OQSA 3WKLA 2P3WA 3SFJA 1U39A 3PV5A 4YYXA 4Q3HA 2M3MA 2OZFA 3VQGA 4JJ0A
chains in the Genus database with same CATH topology
2CSSA 2Z9IA 2WL7A 1P1EA 3TSWA 3NFKA 2YTWA 2JREA 2K1ZA 1L6OA 2M0TA 2IWPA 3ID2A 3CH8A 1Z86A 1WF8A 3L4FD 1WIFA 3QIKA 3CYYA 3NFLA 4JL7A 2H2CA 2LC7A 4F8KA 5EYZA 4OEPA 5B6LA 3TSZA 2EEIA 2M0ZA 3QJNA 4IC6A 5F67A 4NMTA 1U38A 2VSPA 4OAJA 2YT7A 2AWWA 1UJUA 2QKTA 1BFEA 2EHRA 3QDOA 1QAVB 1UJVA 3TMHA 2VSVA 1YBOA 2KQFA 5HEYA 2JINA 2E7KA 2M10A 3GJ9A 1V62A 5A2PA 1WHDA 4NXPA 4H11A 1RZXA 1V6BA 5HETA 4NXQA 3JXTA 3AXAA 4PQWA 4JOHA 4N6XA 2QKVA 3EGHC 1UM1A 4Q2QA 1FC7A 4JOPA 1TQ3A 4JJ3A 1OZIA 1UM7A 2I04A 1Z87A 1W9EA 5G1DA 3HVQC 2KJDA 1WG6A 2HGAA 2VPHA 3GABA 3ID4A 3MH4A 2DC2A 1NTEA 2JILA 2W4FA 4NMRA 3SHUA 2EGKA 2KYLA 2AINA 5HFDA 4NNLA 5ILBA 3EGGC 4K76A 5E21A 1UEPA 2DLUA 2EDVA 1X6DA 2LUIA 5GNDA 2YUBA 2ENOA 4K78A 4G69A 2MX6A 1X5NA 3R0HA 2F0AA 4K6YA 2L4TA 1WFVA 2MHOA 2CS5A 3DIWA 2I6VA 1R6JA 3LNXA 4Z33A 2ZPLA 3K50A 4LMMA 2KRGA 2OPGA 4FLNA 1WF7A 2GZVA 5B42A 2I0IA 3I4WA 3CC0A 2KOMA 2G5MB 2QBWA 4L8NA 3MH6A 1TP3A 3KZEA 2DLSA 2YT8A 1X5RA 4K72A 5HEDA 2EXGA 1SOZA 1BE9A 2IWQA 1V1TA 1NF3C 3QE1A 3CBYA 1UITA 2KA9A 2YUYA 3PS4A 2Q9VA 2VZ5A 2D90A 5DTHA 2JXOA 2EV8A 3GCOA 4NMPA 2LC6A 1X8SA 3STJA 2EAQA 2OS6A 1UEWA 4UU5A 3CBZA 2UZCA 1SOTA 3HPMA 4HOPA 1I16A 1UEQA 3ZRTA 1N6DA 2JWEA 1VA8A 3TSVA 3QGLA 1N7FA 3K1RA 1QAUA 1UEZA 5E11A 3GSLA 1Q3OA 2RCZA 3ID1A 5D13A 1T2MA 1WJLA 1LCYA 3DJ1A 2DAZA 1U37A 3KHFA 2PKUA 3PDVA 4NMQA 2ZPMA 3DJAA 2CSJA 2HE4A 2EGOA 5HJ1A 4O06A 2PKTA 3RLEA 4JORA 3B76A 5H3JA 2PA1A 2I4SA 1UFXA 5JXBA 3FY5A 5GLJA 3RL7A 2KOHA 4RI0A 3NGHA 2EDPA 1N7TA 1FCFA 2O2TA 1FC9A 1M5ZA 2KAWA 1VAEA 3HPKA 2L4SA 5E6PB 1X9ZA 4WYUA 1FC6A 2H3LA 2K20A 1PDRA 1TE0A 5HFEA 2I0LA 1G9OA 3R68A 4JOJA 3DJ3A 2EEHA 2R4HA 1XZ9A 4KFWA 2QKUA 3QJMA 4Q2OA 2Z17A 4R2ZA 2PDZA 5HFCA 3PDZA 1VCWA 4Q6HA 2LOBA 1KWAA 1OBYA 3I1EA 3SHWA 1MC7A 1VJ6A 2REYA 5HDYA 2KJPA 1Q7XA 2H3MA 2F5YA 2RRMA 1Y8TA 2KG2A 1N7EA 2DMZA 1MFGA 1Y7NA 2JIKA 1Q3PA 2FN5A 2GEFA 1WI4A 2I1NA 2FCFA 4AMHA 4OEOA 2W7RA 3CBXA 2HE2A 5EZ0A 2L97A 1IU0A 1B8QA 1WI2A 4Q6SA 4E34A 1I92A 3BPUA 2OSGA 5HF1A 3RL8A 2LA8A 2KL1A 5F3XA 1UF1A 1N6FA 4REYA 2EEJA 1GQ5A 1QAVA 3I18A 1U3BA 2H2BA 1WHAA 4WYTA 5FHTA 1WH1A 2IWOA 5E1YA 3GDSA 1ZOKA 2M0UA 1GQ4A 2Q3GA 4GVDA 1UHPA 1WFGA 3VQFA 1IU2A 4JOGA 2PZDA 1X45A 1GM1A 2PNTA 2KJKA 4JOEA 3KZDA 1KY9A 2JSNA 1KEFA 2QG1A 1K32A 3MH7A 4E35A 2VRFA 4NMVA 2M0VA 5HF4A 4EDJA 1N6EA 3OU0A 4NXRA 4NMSA 4UU6A 2DM8A 2AWUA 2EJYA 2D8IA 2DJTA 2KPKA 4GVCA 4K75A 1QLCA 2AWXA 3GGEA 2V1WA 1D5GA 1N99A 4Z8JA 1UJDA 3NCVA 5HFFA 3O5NA 4KFVA 3GDUA 4NMOA 1V5QA 2X7ZA 3OTPA 3GDVA 5IL9A 2G2LA 2V90A 2DB5A 3PV2A 2DKRA 4Q2NA 4GHNA 1RY4A 4HOPB 1OBXA 1TP5A 1IHJA 2OGPA 2IWNA 3LNYA 1V5LA 2KPLA 2R3YA 1P1DA 3KDKA 5HEBA 2BYGA 5E22A 2EDZA 3ID3A 3KDGA 4NNMA 1MFLA 5HFBA 2KV8A 1VB7A 3WKMA 2EEGA 3PV4A 2KOJA 1ZUBA 1W9QA 1RGRA 4JOKA 2VWRA 2D92A 2QT5A 3R69A 4FGMA 5I7ZA 4MPAA 3O46A 5FB8C 3SOEA 5G1EA 3CS0A 2JOAA 1OBZA 4P2AB 1X5QA 3E17A 1RGWA 4Q2PA 1W9OA 2FE5A 4XHVA 2FNEA 4E3BA 2EGNA 3QO6A 4JOFA 3GCNA 4YDPA 3DORA 4P0CA 3K82A 2OMJA 2KBSA 2OCSA 3SUZA 2OQSA 3WKLA 2P3WA 3SFJA 1U39A 3PV5A 4YYXA 4Q3HA 2M3MA 2OZFA 3VQGA 4JJ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CSS A;  2Z9I A;  2WL7 A;  1P1E A;  3TSW A;  3NFK A;  2YTW A;  2JRE A;  2K1Z A;  1L6O A;  2M0T A;  2IWP A;  3ID2 A;  3CH8 A;  1Z86 A;  1WF8 A;  3L4F D;  1WIF A;  3QIK A;  3CYY A;  3NFL A;  4JL7 A;  2H2C A;  2LC7 A;  4F8K A;  5EYZ A;  4OEP A;  5B6L A;  3TSZ A;  2EEI A;  2M0Z A;  3QJN A;  4IC6 A;  5F67 A;  4NMT A;  1U38 A;  2VSP A;  4OAJ A;  2YT7 A;  2AWW A;  1UJU A;  2QKT A;  1BFE A;  2EHR A;  3QDO A;  1QAV B;  1UJV A;  3TMH A;  2VSV A;  1YBO A;  2KQF A;  5HEY A;  2JIN A;  2E7K A;  2M10 A;  3GJ9 A;  1V62 A;  5A2P A;  1WHD A;  4NXP A;  4H11 A;  1RZX A;  1V6B A;  5HET A;  4NXQ A;  3JXT A;  3AXA A;  4PQW A;  4JOH A;  4N6X A;  2QKV A;  3EGH C;  1UM1 A;  4Q2Q A;  1FC7 A;  4JOP A;  1TQ3 A;  1OZI A;  1UM7 A;  2I04 A;  1Z87 A;  1W9E A;  5G1D A;  3HVQ C;  2KJD A;  1WG6 A;  2HGA A;  2VPH A;  3MH4 A;  3ID4 A;  2DC2 A;  1NTE A;  2JIL A;  2W4F A;  4NMR A;  3SHU A;  2EGK A;  2KYL A;  2AIN A;  5HFD A;  4NNL A;  3EGG C;  4K76 A;  5E21 A;  1UEP A;  2DLU A;  2EDV A;  1X6D A;  2LUI A;  5GND A;  2YUB A;  2ENO A;  4K78 A;  4G69 A;  2MX6 A;  1X5N A;  3R0H A;  2F0A A;  4K6Y A;  2L4T A;  1WFV A;  2MHO A;  2CS5 A;  3DIW A;  2I6V A;  1R6J A;  3LNX A;  4Z33 A;  2ZPL A;  3K50 A;  4LMM A;  2KRG A;  2OPG A;  1WF7 A;  2GZV A;  2I0I A;  3I4W A;  3CC0 A;  2KOM A;  2G5M B;  2QBW A;  4L8N A;  3MH6 A;  1TP3 A;  3KZE A;  2DLS A;  2YT8 A;  1X5R A;  4K72 A;  5HED A;  2EXG A;  1SOZ A;  1BE9 A;  2IWQ A;  1V1T A;  1NF3 C;  3QE1 A;  3CBY A;  1UIT A;  2KA9 A;  2YUY A;  3PS4 A;  2Q9V A;  2VZ5 A;  2D90 A;  5DTH A;  2JXO A;  2EV8 A;  3GCO A;  4NMP A;  2LC6 A;  1X8S A;  3STJ A;  2EAQ A;  2OS6 A;  1UEW A;  4UU5 A;  3CBZ A;  2UZC A;  1SOT A;  3HPM A;  4HOP A;  1I16 A;  1UEQ A;  3ZRT A;  1N6D A;  2JWE A;  1VA8 A;  3TSV A;  3QGL A;  1N7F A;  3K1R A;  1QAU A;  1UEZ A;  5E11 A;  3GSL A;  1Q3O A;  2RCZ A;  3ID1 A;  5D13 A;  1T2M A;  1WJL A;  1LCY A;  3DJ1 A;  2DAZ A;  1U37 A;  3KHF A;  2PKU A;  3PDV A;  4NMQ A;  2ZPM A;  3DJA A;  2CSJ A;  2HE4 A;  2EGO A;  5HJ1 A;  4O06 A;  2PKT A;  3RLE A;  4JOR A;  3B76 A;  5H3J A;  2PA1 A;  2I4S A;  1UFX A;  5JXB A;  3FY5 A;  5GLJ A;  3RL7 A;  2KOH A;  4RI0 A;  3NGH A;  2EDP A;  1N7T A;  1FCF A;  2O2T A;  1FC9 A;  1M5Z A;  2KAW A;  1VAE A;  3HPK A;  2L4S A;  5E6P B;  4WYU A;  1FC6 A;  2H3L A;  2K20 A;  1PDR A;  1TE0 A;  5HFE A;  2I0L A;  1G9O A;  3R68 A;  4JOJ A;  3DJ3 A;  2EEH A;  2R4H A;  1XZ9 A;  4KFW A;  2QKU A;  3QJM A;  4Q2O A;  2Z17 A;  4R2Z A;  2PDZ A;  5HFC A;  3PDZ A;  1VCW A;  4Q6H A;  2LOB A;  1KWA A;  1OBY A;  3I1E A;  3SHW A;  1MC7 A;  1VJ6 A;  2REY A;  5HDY A;  2KJP A;  1Q7X A;  2H3M A;  2F5Y A;  2RRM A;  1Y8T A;  2KG2 A;  1N7E A;  2DMZ A;  1MFG A;  1Y7N A;  2JIK A;  1Q3P A;  2FN5 A;  2I1N A;  1WI4 A;  2FCF A;  4AMH A;  4OEO A;  2W7R A;  3CBX A;  2HE2 A;  5EZ0 A;  2L97 A;  1IU0 A;  1B8Q A;  1WI2 A;  4Q6S A;  4E34 A;  1I92 A;  3BPU A;  2OSG A;  5HF1 A;  3RL8 A;  2LA8 A;  2KL1 A;  5F3X A;  1UF1 A;  1N6F A;  4REY A;  2EEJ A;  1GQ5 A;  1QAV A;  3I18 A;  1U3B A;  2H2B A;  1WHA A;  4WYT A;  5FHT A;  1WH1 A;  2IWO A;  5E1Y A;  3GDS A;  1ZOK A;  2M0U A;  1GQ4 A;  2Q3G A;  4GVD A;  1UHP A;  1WFG A;  3VQF A;  1IU2 A;  4JOG A;  2PZD A;  1X45 A;  1GM1 A;  2PNT A;  2KJK A;  4JOE A;  3KZD A;  1KY9 A;  1KEF A;  2QG1 A;  1K32 A;  3MH7 A;  4E35 A;  2VRF A;  4NMV A;  2M0V A;  5HF4 A;  4EDJ A;  1N6E A;  3OU0 A;  4NXR A;  4NMS A;  4UU6 A;  2DM8 A;  2AWU A;  2EJY A;  2D8I A;  2DJT A;  2KPK A;  4GVC A;  4K75 A;  1QLC A;  2AWX A;  3GGE A;  2V1W A;  1D5G A;  1N99 A;  4Z8J A;  1UJD A;  5HFF A;  3O5N A;  4KFV A;  3GDU A;  4NMO A;  1V5Q A;  2X7Z A;  3OTP A;  3GDV A;  2G2L A;  2V90 A;  2DB5 A;  3PV2 A;  2DKR A;  4Q2N A;  4GHN A;  1RY4 A;  4HOP B;  1OBX A;  1TP5 A;  1IHJ A;  2OGP A;  2IWN A;  3LNY A;  1V5L A;  2KPL A;  2R3Y A;  1P1D A;  5HEB A;  2BYG A;  5E22 A;  2EDZ A;  3ID3 A;  4NNM A;  1MFL A;  5HFB A;  2KV8 A;  1VB7 A;  3WKM A;  2EEG A;  3PV4 A;  2KOJ A;  1ZUB A;  1W9Q A;  1RGR A;  4JOK A;  2VWR A;  2D92 A;  2QT5 A;  3R69 A;  4FGM A;  5I7Z A;  4MPA A;  3O46 A;  5FB8 C;  3SOE A;  5G1E A;  3CS0 A;  2JOA A;  1OBZ A;  4P2A B;  1X5Q A;  3E17 A;  1RGW A;  4Q2P A;  1W9O A;  2FE5 A;  4XHV A;  2FNE A;  4E3B A;  2EGN A;  3QO6 A;  4JOF A;  3GCN A;  4YDP A;  3DOR A;  4P0C A;  3K82 A;  2OMJ A;  2KBS A;  2OCS A;  3SUZ A;  2OQS A;  3WKL A;  2P3W A;  3SFJ A;  1U39 A;  3PV5 A;  4YYX A;  4Q3H A;  2M3M A;  2OZF A;  3VQG A; 
#chains in the Genus database with same CATH topology
 2CSS A;  2Z9I A;  2WL7 A;  1P1E A;  3TSW A;  3NFK A;  2YTW A;  2JRE A;  2K1Z A;  1L6O A;  2M0T A;  2IWP A;  3ID2 A;  3CH8 A;  1Z86 A;  1WF8 A;  3L4F D;  1WIF A;  3QIK A;  3CYY A;  3NFL A;  4JL7 A;  2H2C A;  2LC7 A;  4F8K A;  5EYZ A;  4OEP A;  5B6L A;  3TSZ A;  2EEI A;  2M0Z A;  3QJN A;  4IC6 A;  5F67 A;  4NMT A;  1U38 A;  2VSP A;  4OAJ A;  2YT7 A;  2AWW A;  1UJU A;  2QKT A;  1BFE A;  2EHR A;  3QDO A;  1QAV B;  1UJV A;  3TMH A;  2VSV A;  1YBO A;  2KQF A;  5HEY A;  2JIN A;  2E7K A;  2M10 A;  3GJ9 A;  1V62 A;  5A2P A;  1WHD A;  4NXP A;  4H11 A;  1RZX A;  1V6B A;  5HET A;  4NXQ A;  3JXT A;  3AXA A;  4PQW A;  4JOH A;  4N6X A;  2QKV A;  3EGH C;  1UM1 A;  4Q2Q A;  1FC7 A;  4JOP A;  1TQ3 A;  4JJ3 A;  1OZI A;  1UM7 A;  2I04 A;  1Z87 A;  1W9E A;  5G1D A;  3HVQ C;  2KJD A;  1WG6 A;  2HGA A;  2VPH A;  3GAB A;  3ID4 A;  3MH4 A;  2DC2 A;  1NTE A;  2JIL A;  2W4F A;  4NMR A;  3SHU A;  2EGK A;  2KYL A;  2AIN A;  5HFD A;  4NNL A;  5ILB A;  3EGG C;  4K76 A;  5E21 A;  1UEP A;  2DLU A;  2EDV A;  1X6D A;  2LUI A;  5GND A;  2YUB A;  2ENO A;  4K78 A;  4G69 A;  2MX6 A;  1X5N A;  3R0H A;  2F0A A;  4K6Y A;  2L4T A;  1WFV A;  2MHO A;  2CS5 A;  3DIW A;  2I6V A;  1R6J A;  3LNX A;  4Z33 A;  2ZPL A;  3K50 A;  4LMM A;  2KRG A;  2OPG A;  4FLN A;  1WF7 A;  2GZV A;  5B42 A;  2I0I A;  3I4W A;  3CC0 A;  2KOM A;  2G5M B;  2QBW A;  4L8N A;  3MH6 A;  1TP3 A;  3KZE A;  2DLS A;  2YT8 A;  1X5R A;  4K72 A;  5HED A;  2EXG A;  1SOZ A;  1BE9 A;  2IWQ A;  1V1T A;  1NF3 C;  3QE1 A;  3CBY A;  1UIT A;  2KA9 A;  2YUY A;  3PS4 A;  2Q9V A;  2VZ5 A;  2D90 A;  5DTH A;  2JXO A;  2EV8 A;  3GCO A;  4NMP A;  2LC6 A;  1X8S A;  3STJ A;  2EAQ A;  2OS6 A;  1UEW A;  4UU5 A;  3CBZ A;  2UZC A;  1SOT A;  3HPM A;  4HOP A;  1I16 A;  1UEQ A;  3ZRT A;  1N6D A;  2JWE A;  1VA8 A;  3TSV A;  3QGL A;  1N7F A;  3K1R A;  1QAU A;  1UEZ A;  5E11 A;  3GSL A;  1Q3O A;  2RCZ A;  3ID1 A;  5D13 A;  1T2M A;  1WJL A;  1LCY A;  3DJ1 A;  2DAZ A;  1U37 A;  3KHF A;  2PKU A;  3PDV A;  4NMQ A;  2ZPM A;  3DJA A;  2CSJ A;  2HE4 A;  2EGO A;  5HJ1 A;  4O06 A;  2PKT A;  3RLE A;  4JOR A;  3B76 A;  5H3J A;  2PA1 A;  2I4S A;  1UFX A;  5JXB A;  3FY5 A;  5GLJ A;  3RL7 A;  2KOH A;  4RI0 A;  3NGH A;  2EDP A;  1N7T A;  1FCF A;  2O2T A;  1FC9 A;  1M5Z A;  2KAW A;  1VAE A;  3HPK A;  2L4S A;  5E6P B;  1X9Z A;  4WYU A;  1FC6 A;  2H3L A;  2K20 A;  1PDR A;  1TE0 A;  5HFE A;  2I0L A;  1G9O A;  3R68 A;  4JOJ A;  3DJ3 A;  2EEH A;  2R4H A;  1XZ9 A;  4KFW A;  2QKU A;  3QJM A;  4Q2O A;  2Z17 A;  4R2Z A;  2PDZ A;  5HFC A;  3PDZ A;  1VCW A;  4Q6H A;  2LOB A;  1KWA A;  1OBY A;  3I1E A;  3SHW A;  1MC7 A;  1VJ6 A;  2REY A;  5HDY A;  2KJP A;  1Q7X A;  2H3M A;  2F5Y A;  2RRM A;  1Y8T A;  2KG2 A;  1N7E A;  2DMZ A;  1MFG A;  1Y7N A;  2JIK A;  1Q3P A;  2FN5 A;  2GEF A;  1WI4 A;  2I1N A;  2FCF A;  4AMH A;  4OEO A;  2W7R A;  3CBX A;  2HE2 A;  5EZ0 A;  2L97 A;  1IU0 A;  1B8Q A;  1WI2 A;  4Q6S A;  4E34 A;  1I92 A;  3BPU A;  2OSG A;  5HF1 A;  3RL8 A;  2LA8 A;  2KL1 A;  5F3X A;  1UF1 A;  1N6F A;  4REY A;  2EEJ A;  1GQ5 A;  1QAV A;  3I18 A;  1U3B A;  2H2B A;  1WHA A;  4WYT A;  5FHT A;  1WH1 A;  2IWO A;  5E1Y A;  3GDS A;  1ZOK A;  2M0U A;  1GQ4 A;  2Q3G A;  4GVD A;  1UHP A;  1WFG A;  3VQF A;  1IU2 A;  4JOG A;  2PZD A;  1X45 A;  1GM1 A;  2PNT A;  2KJK A;  4JOE A;  3KZD A;  1KY9 A;  2JSN A;  1KEF A;  2QG1 A;  1K32 A;  3MH7 A;  4E35 A;  2VRF A;  4NMV A;  2M0V A;  5HF4 A;  4EDJ A;  1N6E A;  3OU0 A;  4NXR A;  4NMS A;  4UU6 A;  2DM8 A;  2AWU A;  2EJY A;  2D8I A;  2DJT A;  2KPK A;  4GVC A;  4K75 A;  1QLC A;  2AWX A;  3GGE A;  2V1W A;  1D5G A;  1N99 A;  4Z8J A;  1UJD A;  3NCV A;  5HFF A;  3O5N A;  4KFV A;  3GDU A;  4NMO A;  1V5Q A;  2X7Z A;  3OTP A;  3GDV A;  5IL9 A;  2G2L A;  2V90 A;  2DB5 A;  3PV2 A;  2DKR A;  4Q2N A;  4GHN A;  1RY4 A;  4HOP B;  1OBX A;  1TP5 A;  1IHJ A;  2OGP A;  2IWN A;  3LNY A;  1V5L A;  2KPL A;  2R3Y A;  1P1D A;  3KDK A;  5HEB A;  2BYG A;  5E22 A;  2EDZ A;  3ID3 A;  3KDG A;  4NNM A;  1MFL A;  5HFB A;  2KV8 A;  1VB7 A;  3WKM A;  2EEG A;  3PV4 A;  2KOJ A;  1ZUB A;  1W9Q A;  1RGR A;  4JOK A;  2VWR A;  2D92 A;  2QT5 A;  3R69 A;  4FGM A;  5I7Z A;  4MPA A;  3O46 A;  5FB8 C;  3SOE A;  5G1E A;  3CS0 A;  2JOA A;  1OBZ A;  4P2A B;  1X5Q A;  3E17 A;  1RGW A;  4Q2P A;  1W9O A;  2FE5 A;  4XHV A;  2FNE A;  4E3B A;  2EGN A;  3QO6 A;  4JOF A;  3GCN A;  4YDP A;  3DOR A;  4P0C A;  3K82 A;  2OMJ A;  2KBS A;  2OCS A;  3SUZ A;  2OQS A;  3WKL A;  2P3W A;  3SFJ A;  1U39 A;  3PV5 A;  4YYX A;  4Q3H A;  2M3M A;  2OZF A;  3VQG A;  4JJ0 A; 
#chains in the Genus database with same CATH homology
 2CSS A;  2Z9I A;  2WL7 A;  1P1E A;  3TSW A;  3NFK A;  2YTW A;  2JRE A;  2K1Z A;  1L6O A;  2M0T A;  2IWP A;  3ID2 A;  3CH8 A;  1Z86 A;  1WF8 A;  3L4F D;  1WIF A;  3QIK A;  3CYY A;  3NFL A;  4JL7 A;  2H2C A;  2LC7 A;  4F8K A;  5EYZ A;  4OEP A;  5B6L A;  3TSZ A;  2EEI A;  2M0Z A;  3QJN A;  4IC6 A;  5F67 A;  4NMT A;  1U38 A;  2VSP A;  4OAJ A;  2YT7 A;  2AWW A;  1UJU A;  2QKT A;  1BFE A;  2EHR A;  3QDO A;  1QAV B;  1UJV A;  3TMH A;  2VSV A;  1YBO A;  2KQF A;  5HEY A;  2JIN A;  2E7K A;  2M10 A;  3GJ9 A;  1V62 A;  5A2P A;  1WHD A;  4NXP A;  4H11 A;  1RZX A;  1V6B A;  5HET A;  4NXQ A;  3JXT A;  3AXA A;  4PQW A;  4JOH A;  4N6X A;  2QKV A;  3EGH C;  1UM1 A;  4Q2Q A;  1FC7 A;  4JOP A;  1TQ3 A;  4JJ3 A;  1OZI A;  1UM7 A;  2I04 A;  1Z87 A;  1W9E A;  5G1D A;  3HVQ C;  2KJD A;  1WG6 A;  2HGA A;  2VPH A;  3GAB A;  3ID4 A;  3MH4 A;  2DC2 A;  1NTE A;  2JIL A;  2W4F A;  4NMR A;  3SHU A;  2EGK A;  2KYL A;  2AIN A;  5HFD A;  4NNL A;  5ILB A;  3EGG C;  4K76 A;  5E21 A;  1UEP A;  2DLU A;  2EDV A;  1X6D A;  2LUI A;  5GND A;  2YUB A;  2ENO A;  4K78 A;  4G69 A;  2MX6 A;  1X5N A;  3R0H A;  2F0A A;  4K6Y A;  2L4T A;  1WFV A;  2MHO A;  2CS5 A;  3DIW A;  2I6V A;  1R6J A;  3LNX A;  4Z33 A;  2ZPL A;  3K50 A;  4LMM A;  2KRG A;  2OPG A;  4FLN A;  1WF7 A;  2GZV A;  5B42 A;  2I0I A;  3I4W A;  3CC0 A;  2KOM A;  2G5M B;  2QBW A;  4L8N A;  3MH6 A;  1TP3 A;  3KZE A;  2DLS A;  2YT8 A;  1X5R A;  4K72 A;  5HED A;  2EXG A;  1SOZ A;  1BE9 A;  2IWQ A;  1V1T A;  1NF3 C;  3QE1 A;  3CBY A;  1UIT A;  2KA9 A;  2YUY A;  3PS4 A;  2Q9V A;  2VZ5 A;  2D90 A;  5DTH A;  2JXO A;  2EV8 A;  3GCO A;  4NMP A;  2LC6 A;  1X8S A;  3STJ A;  2EAQ A;  2OS6 A;  1UEW A;  4UU5 A;  3CBZ A;  2UZC A;  1SOT A;  3HPM A;  4HOP A;  1I16 A;  1UEQ A;  3ZRT A;  1N6D A;  2JWE A;  1VA8 A;  3TSV A;  3QGL A;  1N7F A;  3K1R A;  1QAU A;  1UEZ A;  5E11 A;  3GSL A;  1Q3O A;  2RCZ A;  3ID1 A;  5D13 A;  1T2M A;  1WJL A;  1LCY A;  3DJ1 A;  2DAZ A;  1U37 A;  3KHF A;  2PKU A;  3PDV A;  4NMQ A;  2ZPM A;  3DJA A;  2CSJ A;  2HE4 A;  2EGO A;  5HJ1 A;  4O06 A;  2PKT A;  3RLE A;  4JOR A;  3B76 A;  5H3J A;  2PA1 A;  2I4S A;  1UFX A;  5JXB A;  3FY5 A;  5GLJ A;  3RL7 A;  2KOH A;  4RI0 A;  3NGH A;  2EDP A;  1N7T A;  1FCF A;  2O2T A;  1FC9 A;  1M5Z A;  2KAW A;  1VAE A;  3HPK A;  2L4S A;  5E6P B;  1X9Z A;  4WYU A;  1FC6 A;  2H3L A;  2K20 A;  1PDR A;  1TE0 A;  5HFE A;  2I0L A;  1G9O A;  3R68 A;  4JOJ A;  3DJ3 A;  2EEH A;  2R4H A;  1XZ9 A;  4KFW A;  2QKU A;  3QJM A;  4Q2O A;  2Z17 A;  4R2Z A;  2PDZ A;  5HFC A;  3PDZ A;  1VCW A;  4Q6H A;  2LOB A;  1KWA A;  1OBY A;  3I1E A;  3SHW A;  1MC7 A;  1VJ6 A;  2REY A;  5HDY A;  2KJP A;  1Q7X A;  2H3M A;  2F5Y A;  2RRM A;  1Y8T A;  2KG2 A;  1N7E A;  2DMZ A;  1MFG A;  1Y7N A;  2JIK A;  1Q3P A;  2FN5 A;  2GEF A;  1WI4 A;  2I1N A;  2FCF A;  4AMH A;  4OEO A;  2W7R A;  3CBX A;  2HE2 A;  5EZ0 A;  2L97 A;  1IU0 A;  1B8Q A;  1WI2 A;  4Q6S A;  4E34 A;  1I92 A;  3BPU A;  2OSG A;  5HF1 A;  3RL8 A;  2LA8 A;  2KL1 A;  5F3X A;  1UF1 A;  1N6F A;  4REY A;  2EEJ A;  1GQ5 A;  1QAV A;  3I18 A;  1U3B A;  2H2B A;  1WHA A;  4WYT A;  5FHT A;  1WH1 A;  2IWO A;  5E1Y A;  3GDS A;  1ZOK A;  2M0U A;  1GQ4 A;  2Q3G A;  4GVD A;  1UHP A;  1WFG A;  3VQF A;  1IU2 A;  4JOG A;  2PZD A;  1X45 A;  1GM1 A;  2PNT A;  2KJK A;  4JOE A;  3KZD A;  1KY9 A;  2JSN A;  1KEF A;  2QG1 A;  1K32 A;  3MH7 A;  4E35 A;  2VRF A;  4NMV A;  2M0V A;  5HF4 A;  4EDJ A;  1N6E A;  3OU0 A;  4NXR A;  4NMS A;  4UU6 A;  2DM8 A;  2AWU A;  2EJY A;  2D8I A;  2DJT A;  2KPK A;  4GVC A;  4K75 A;  1QLC A;  2AWX A;  3GGE A;  2V1W A;  1D5G A;  1N99 A;  4Z8J A;  1UJD A;  3NCV A;  5HFF A;  3O5N A;  4KFV A;  3GDU A;  4NMO A;  1V5Q A;  2X7Z A;  3OTP A;  3GDV A;  5IL9 A;  2G2L A;  2V90 A;  2DB5 A;  3PV2 A;  2DKR A;  4Q2N A;  4GHN A;  1RY4 A;  4HOP B;  1OBX A;  1TP5 A;  1IHJ A;  2OGP A;  2IWN A;  3LNY A;  1V5L A;  2KPL A;  2R3Y A;  1P1D A;  3KDK A;  5HEB A;  2BYG A;  5E22 A;  2EDZ A;  3ID3 A;  3KDG A;  4NNM A;  1MFL A;  5HFB A;  2KV8 A;  1VB7 A;  3WKM A;  2EEG A;  3PV4 A;  2KOJ A;  1ZUB A;  1W9Q A;  1RGR A;  4JOK A;  2VWR A;  2D92 A;  2QT5 A;  3R69 A;  4FGM A;  5I7Z A;  4MPA A;  3O46 A;  5FB8 C;  3SOE A;  5G1E A;  3CS0 A;  2JOA A;  1OBZ A;  4P2A B;  1X5Q A;  3E17 A;  1RGW A;  4Q2P A;  1W9O A;  2FE5 A;  4XHV A;  2FNE A;  4E3B A;  2EGN A;  3QO6 A;  4JOF A;  3GCN A;  4YDP A;  3DOR A;  4P0C A;  3K82 A;  2OMJ A;  2KBS A;  2OCS A;  3SUZ A;  2OQS A;  3WKL A;  2P3W A;  3SFJ A;  1U39 A;  3PV5 A;  4YYX A;  4Q3H A;  2M3M A;  2OZF A;  3VQG A;  4JJ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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