4P0CA

Crystal structure of nherf2 pdz1 domain in complex with lpa2
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
88
structure length
88
Chain Sequence
MPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQMDSTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Na(+)/H(+) exchange regulatory cofactor NHE-RF2/Lysophosphat
total genus 17
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2014-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 4p0cA00
4E35A 5E6PB 1FC6A 2D90A 2OS6A 4JOPA 2MX6A 1UJDA 4K6YA 4YDPA 1KY9A 2H3LA 1KWAA 1VAEA 1UITA 5HEBA 5HF4A 3OTPA 1OBXA 1UFXA 1Z86A 2I04A 3EGGC 5HFCA 3WKMA 4JOGA 2E7KA 3LNYA 4NMTA 1UEWA 4OAJA 2M0VA 1WI4A 2KRGA 3R68A 4Q3HA 5GLJA 2FCFA 1UHPA 1P1DA 2LC7A 2EJYA 2EXGA 2YT7A 5F3XA 1GQ5A 1V1TA 2F5YA 4GVCA 1FCFA 4JORA 2DMZA 3DIWA 2LUIA 4JOKA 3QDOA 2OQSA 1N7EA 2AWUA 4NMVA 2EDPA 1N7FA 2KG2A 2PZDA 3CBXA 2EDVA 2EEGA 2QKVA 2H2CA 1OBYA 1X45A 2I0IA 3CS0A 2I6VA 2YTWA 1QAUA 3QJNA 2OSGA 3PV2A 3CH8A 2CSSA 2LC6A 1SOZA 3K82A 2ENOA 5G1EA 1W9EA 2YUBA 2JILA 1IU2A 1WFVA 2KJDA 2MHOA 5H3JA 1QAVB 2KJKA 1WG6A 4NXQA 1TP3A 4NMRA 1X6DA 3VQFA 4WYUA 2QBWA 3I4WA 2X7ZA 2RRMA 2AINA 2V90A 1XZ9A 2KV8A 1GQ4A 2JXOA 4JOJA 4OEPA 2VSVA 2BYGA 2PA1A 1QLCA 2KA9A 2R3YA 4UU6A 1Q3PA 1PDRA 4PQWA 4Q2NA 1L6OA 1TP5A 2EGKA 3EGHC 3QGLA 1TQ3A 1RGWA 3TSWA 1FC7A 3CC0A 2CS5A 3HVQC 3GSLA 2L4SA 3TMHA 3KZEA 2K1ZA 1IU0A 3OU0A 2YUYA 3ZRTA 2FN5A 1V5LA 3RL7A 3L4FD 1WFGA 2JIKA 3PDZA 1RGRA 1U37A 4Z8JA 3NFLA 2VSPA 1U38A 4Q2PA 1U39A 2KPLA 1Y8TA 1B8QA 2G5MB 4HOPB 5E11A 1UEPA 5D13A 1UEQA 1V5QA 2KL1A 5EYZA 4E3BA 3GCOA 4P0CA 3DJAA 4MPAA 2JWEA 3SFJA 4P2AB 4HOPA 3GDVA 1ZOKA 3K50A 1UJUA 4H11A 4GHNA 2M0TA 2H2BA 1N7TA 4UU5A 2O2TA 3ID4A 2Z9IA 2ZPMA 2EHRA 3CBZA 4Q2OA 1X5NA 1R6JA 1GM1A 3E17A 2QG1A 2I0LA 1UEZA 1VCWA 3GDUA 2I4SA 1Q3OA 5G1DA 2DC2A 1I92A 2M10A 4F8KA 4Q6HA 2JOAA 2I1NA 1NF3C 2D8IA 5FB8C 5GNDA 1VA8A 2HGAA 1WHDA 1WH1A 3O5NA 2WL7A 3I18A 2FNEA 1N99A 5HJ1A 1Y7NA 2L97A 2G2LA 5HEDA 1OZIA 1UF1A 2KOJA 3PS4A 2V1WA 1D5GA 2QKUA 3QO6A 1VJ6A 3PDVA 1W9OA 1X8SA 1P1EA 1V62A 2DB5A 2KBSA 2OCSA 2PKTA 5HFFA 1IHJA 1K32A 2LOBA 2W7RA 2QT5A 2YT8A 2EGNA 2CSJA 1WIFA 2UZCA 2VWRA 3HPMA 1ZUBA 5I7ZA 1Z87A 5E1YA 1I16A 2IWOA 2VPHA 1OBZA 1T2MA 3R0HA 5E22A 2PKUA 2KOHA 4GVDA 2DM8A 4XHVA 4JOHA 2KQFA 2EEHA 3GCNA 2EGOA 2EEJA 3RLEA 4Z33A 2REYA 2QKTA 3K1RA 2HE2A 2KJPA 3R69A 1KEFA 3KHFA 2ZPLA 3DORA 2F0AA 3GGEA 3CYYA 3VQGA 4G69A 3RL8A 2L4TA 2DJTA 4N6XA 2RCZA 1G9OA 2W4FA 3KZDA 3LNXA 4JOEA 4K78A 3HPKA 2M3MA 3PV5A 4IC6A 1BFEA 2VZ5A 2IWNA 1W9QA 4NMOA 4AMHA 2VRFA 3SUZA 5HEYA 2OGPA 4KFWA 3GDSA 1WF7A 2R4HA 3ID2A 3MH7A 1U3BA 2OMJA 4NMSA 3JXTA 3O46A 2FE5A 3SHWA 2IWQA 4RI0A 1UJVA 2AWXA 2M0UA 4WYTA 4NMPA 3SOEA 4NNMA 2KOMA 4L8NA 4JOFA 5F67A 4K76A 3MH6A 1X5RA 1YBOA 1N6EA 3TSVA 1WJLA 3B76A 2K20A 3FY5A 5HFEA 4NXPA 2GZVA 3DJ1A 2JINA 1N6DA 2EEIA 3WKLA 1SOTA 4OEOA 1N6FA 4Q6SA 2Z17A 2EDZA 2LA8A 2M0ZA 4K75A 1V6BA 1M5ZA 4LMMA 2EAQA 3ID1A 3TSZA 3QE1A 3BPUA 2PNTA 3SHUA 5HF1A 3ID3A 3DJ3A 4K72A 4E34A 2P3WA 1WF8A 2KPKA 5EZ0A 2DLUA 4FGMA 1RZXA 2D92A 2KYLA 2H3MA 4NXRA 5FHTA 4REYA 3NGHA 2IWPA 5DTHA 4YYXA 5B6LA 1LCYA 4NMQA 1UM1A 5E21A 5HETA 1BE9A 2KAWA 2DKRA 4O06A 2HE4A 4NNLA 1MFGA 3GJ9A 1RY4A 2DLSA 2AWWA 1TE0A 1WHAA 3MH4A 2EV8A 1QAVA 4Q2QA 1UM7A 2JREA 2Q3GA 1X5QA 2OZFA 5HDYA 2PDZA 1VB7A 3CBYA 3NFKA 3QIKA 4KFVA 5HFDA 3AXAA 1MFLA 3PV4A 5A2PA 1MC7A 1WI2A 3QJMA 4R2ZA 5HFBA 5JXBA 2Q9VA 4JL7A 1FC9A 1NTEA 4EDJA 3I1EA 1Q7XA 2OPGA 3STJA 2DAZA
chains in the Genus database with same CATH superfamily
4E35A 3KDKA 5E6PB 1FC6A 2D90A 2OS6A 4JOPA 2MX6A 1UJDA 4K6YA 4YDPA 1KY9A 2H3LA 1KWAA 1VAEA 1UITA 5HEBA 5HF4A 3OTPA 1OBXA 1UFXA 1Z86A 2I04A 3EGGC 5HFCA 3WKMA 4JOGA 2E7KA 3LNYA 4NMTA 1UEWA 4OAJA 2M0VA 1WI4A 2KRGA 3R68A 4Q3HA 5GLJA 2FCFA 1UHPA 1P1DA 2LC7A 2EJYA 2EXGA 2YT7A 5F3XA 1GQ5A 1V1TA 2F5YA 4GVCA 1FCFA 4JORA 2DMZA 3DIWA 2LUIA 4JOKA 3QDOA 2OQSA 1N7EA 2AWUA 4NMVA 2EDPA 1N7FA 2KG2A 2PZDA 3CBXA 2EDVA 2EEGA 2QKVA 2H2CA 1OBYA 1X45A 2I0IA 3CS0A 2I6VA 2YTWA 1QAUA 3QJNA 2OSGA 3PV2A 3CH8A 2CSSA 2LC6A 1SOZA 3K82A 2ENOA 5G1EA 1W9EA 2YUBA 2JILA 1IU2A 4JJ0A 1WFVA 2KJDA 2MHOA 5H3JA 1QAVB 2KJKA 1WG6A 4NXQA 1TP3A 4NMRA 1X6DA 3VQFA 4WYUA 2QBWA 3I4WA 2X7ZA 2RRMA 2AINA 2V90A 1XZ9A 2KV8A 1GQ4A 2JXOA 4JOJA 4OEPA 2VSVA 2BYGA 2PA1A 1QLCA 2KA9A 2R3YA 4UU6A 1Q3PA 1PDRA 4PQWA 4Q2NA 1L6OA 1TP5A 2EGKA 3EGHC 3QGLA 1TQ3A 1RGWA 3TSWA 1FC7A 3CC0A 2CS5A 3HVQC 3GSLA 2L4SA 3TMHA 3KZEA 2K1ZA 1IU0A 3OU0A 2YUYA 3ZRTA 2FN5A 1V5LA 3RL7A 3L4FD 1WFGA 2JIKA 3PDZA 1RGRA 1U37A 4Z8JA 3NFLA 2VSPA 1U38A 4Q2PA 1U39A 2KPLA 1Y8TA 1B8QA 2G5MB 4HOPB 5E11A 1UEPA 5D13A 1UEQA 1V5QA 2KL1A 5EYZA 4E3BA 3GCOA 4P0CA 3DJAA 4MPAA 5IL9A 2JWEA 3SFJA 4P2AB 4HOPA 3GDVA 1ZOKA 3K50A 1UJUA 4H11A 4GHNA 2M0TA 2H2BA 1N7TA 4UU5A 2O2TA 3ID4A 2Z9IA 2ZPMA 2EHRA 3CBZA 4Q2OA 1X5NA 1R6JA 1GM1A 3E17A 2QG1A 2I0LA 1UEZA 1VCWA 3GDUA 2I4SA 1Q3OA 5G1DA 2DC2A 1I92A 2M10A 5B42A 3KDGA 4F8KA 4Q6HA 2JOAA 2I1NA 1NF3C 2D8IA 5FB8C 5GNDA 1VA8A 2HGAA 1WHDA 1WH1A 3O5NA 2WL7A 3I18A 2FNEA 1N99A 5HJ1A 1Y7NA 2L97A 2G2LA 5HEDA 1OZIA 1UF1A 2KOJA 3PS4A 2V1WA 1D5GA 2QKUA 3QO6A 1VJ6A 3PDVA 1W9OA 1X8SA 1P1EA 1V62A 2DB5A 2KBSA 2OCSA 2PKTA 5HFFA 1IHJA 1K32A 2LOBA 2W7RA 2QT5A 2YT8A 2EGNA 2CSJA 1WIFA 2UZCA 2VWRA 3HPMA 1ZUBA 5I7ZA 1Z87A 5E1YA 2JSNA 1I16A 2IWOA 2VPHA 1OBZA 1X9ZA 1T2MA 3R0HA 5E22A 2PKUA 2KOHA 4GVDA 2DM8A 4XHVA 4JOHA 2KQFA 2GEFA 2EEHA 3GCNA 2EGOA 2EEJA 3RLEA 4Z33A 2REYA 2QKTA 3K1RA 2HE2A 2KJPA 3R69A 1KEFA 3KHFA 2ZPLA 3DORA 2F0AA 3GGEA 3CYYA 3VQGA 4G69A 3RL8A 2L4TA 2DJTA 3NCVA 4N6XA 2RCZA 1G9OA 2W4FA 3KZDA 3LNXA 4JOEA 4K78A 3HPKA 2M3MA 3PV5A 4IC6A 1BFEA 2VZ5A 2IWNA 1W9QA 4NMOA 4AMHA 2VRFA 3SUZA 5HEYA 2OGPA 4KFWA 3GDSA 1WF7A 2R4HA 3ID2A 3MH7A 1U3BA 2OMJA 4NMSA 3JXTA 3O46A 2FE5A 3SHWA 2IWQA 4RI0A 1UJVA 2AWXA 2M0UA 4WYTA 4NMPA 3SOEA 4NNMA 3GABA 2KOMA 4L8NA 4JOFA 5F67A 4K76A 3MH6A 1X5RA 1YBOA 1N6EA 3TSVA 1WJLA 3B76A 2K20A 3FY5A 5HFEA 4NXPA 2GZVA 3DJ1A 2JINA 1N6DA 2EEIA 3WKLA 1SOTA 4OEOA 1N6FA 4Q6SA 2Z17A 2EDZA 2LA8A 2M0ZA 4K75A 1V6BA 1M5ZA 4LMMA 2EAQA 3ID1A 3TSZA 3QE1A 3BPUA 2PNTA 3SHUA 5HF1A 3ID3A 3DJ3A 4K72A 4E34A 2P3WA 1WF8A 2KPKA 5EZ0A 2DLUA 4FGMA 1RZXA 2D92A 2KYLA 2H3MA 4NXRA 5FHTA 4REYA 3NGHA 2IWPA 5DTHA 4YYXA 5B6LA 1LCYA 4NMQA 1UM1A 5E21A 5HETA 1BE9A 2KAWA 2DKRA 4O06A 2HE4A 4NNLA 1MFGA 3GJ9A 1RY4A 2DLSA 2AWWA 1TE0A 1WHAA 3MH4A 2EV8A 1QAVA 4Q2QA 1UM7A 2JREA 2Q3GA 1X5QA 2OZFA 5HDYA 2PDZA 1VB7A 3CBYA 3NFKA 3QIKA 4KFVA 5HFDA 3AXAA 1MFLA 3PV4A 5A2PA 1MC7A 1WI2A 3QJMA 5ILBA 4JJ3A 4R2ZA 5HFBA 5JXBA 2Q9VA 4JL7A 1FC9A 1NTEA 4EDJA 3I1EA 1Q7XA 2OPGA 4FLNA 3STJA 2DAZA
chains in the Genus database with same CATH topology
4E35A 3KDKA 5E6PB 1FC6A 2D90A 2OS6A 4JOPA 2MX6A 1UJDA 4K6YA 4YDPA 1KY9A 2H3LA 1KWAA 1VAEA 1UITA 5HEBA 5HF4A 3OTPA 1OBXA 1UFXA 1Z86A 2I04A 3EGGC 5HFCA 3WKMA 4JOGA 2E7KA 3LNYA 4NMTA 1UEWA 4OAJA 2M0VA 1WI4A 2KRGA 3R68A 4Q3HA 5GLJA 2FCFA 1UHPA 1P1DA 2LC7A 2EJYA 2EXGA 2YT7A 5F3XA 1GQ5A 1V1TA 2F5YA 4GVCA 1FCFA 4JORA 2DMZA 3DIWA 2LUIA 4JOKA 3QDOA 2OQSA 1N7EA 2AWUA 4NMVA 2EDPA 1N7FA 2KG2A 2PZDA 3CBXA 2EDVA 2EEGA 2QKVA 2H2CA 1OBYA 1X45A 2I0IA 3CS0A 2I6VA 2YTWA 1QAUA 3QJNA 2OSGA 3PV2A 3CH8A 2CSSA 2LC6A 1SOZA 3K82A 2ENOA 5G1EA 1W9EA 2YUBA 2JILA 1IU2A 4JJ0A 1WFVA 2KJDA 2MHOA 5H3JA 1QAVB 2KJKA 1WG6A 4NXQA 1TP3A 4NMRA 1X6DA 3VQFA 4WYUA 2QBWA 3I4WA 2X7ZA 2RRMA 2AINA 2V90A 1XZ9A 2KV8A 1GQ4A 2JXOA 4JOJA 4OEPA 2VSVA 2BYGA 2PA1A 1QLCA 2KA9A 2R3YA 4UU6A 1Q3PA 1PDRA 4PQWA 4Q2NA 1L6OA 1TP5A 2EGKA 3EGHC 3QGLA 1TQ3A 1RGWA 3TSWA 1FC7A 3CC0A 2CS5A 3HVQC 3GSLA 2L4SA 3TMHA 3KZEA 2K1ZA 1IU0A 3OU0A 2YUYA 3ZRTA 2FN5A 1V5LA 3RL7A 3L4FD 1WFGA 2JIKA 3PDZA 1RGRA 1U37A 4Z8JA 3NFLA 2VSPA 1U38A 4Q2PA 1U39A 2KPLA 1Y8TA 1B8QA 2G5MB 4HOPB 5E11A 1UEPA 5D13A 1UEQA 1V5QA 2KL1A 5EYZA 4E3BA 3GCOA 4P0CA 3DJAA 4MPAA 5IL9A 2JWEA 3SFJA 4P2AB 4HOPA 3GDVA 1ZOKA 3K50A 1UJUA 4H11A 4GHNA 2M0TA 2H2BA 1N7TA 4UU5A 2O2TA 3ID4A 2Z9IA 2ZPMA 2EHRA 3CBZA 4Q2OA 1X5NA 1R6JA 1GM1A 3E17A 2QG1A 2I0LA 1UEZA 1VCWA 3GDUA 2I4SA 1Q3OA 5G1DA 2DC2A 1I92A 2M10A 5B42A 3KDGA 4F8KA 4Q6HA 2JOAA 2I1NA 1NF3C 2D8IA 5FB8C 5GNDA 1VA8A 2HGAA 1WHDA 1WH1A 3O5NA 2WL7A 3I18A 2FNEA 1N99A 5HJ1A 1Y7NA 2L97A 2G2LA 5HEDA 1OZIA 1UF1A 2KOJA 3PS4A 2V1WA 1D5GA 2QKUA 3QO6A 1VJ6A 3PDVA 1W9OA 1X8SA 1P1EA 1V62A 2DB5A 2KBSA 2OCSA 2PKTA 5HFFA 1IHJA 1K32A 2LOBA 2W7RA 2QT5A 2YT8A 2EGNA 2CSJA 1WIFA 2UZCA 2VWRA 3HPMA 1ZUBA 5I7ZA 1Z87A 5E1YA 2JSNA 1I16A 2IWOA 2VPHA 1OBZA 1X9ZA 1T2MA 3R0HA 5E22A 2PKUA 2KOHA 4GVDA 2DM8A 4XHVA 4JOHA 2KQFA 2GEFA 2EEHA 3GCNA 2EGOA 2EEJA 3RLEA 4Z33A 2REYA 2QKTA 3K1RA 2HE2A 2KJPA 3R69A 1KEFA 3KHFA 2ZPLA 3DORA 2F0AA 3GGEA 3CYYA 3VQGA 4G69A 3RL8A 2L4TA 2DJTA 3NCVA 4N6XA 2RCZA 1G9OA 2W4FA 3KZDA 3LNXA 4JOEA 4K78A 3HPKA 2M3MA 3PV5A 4IC6A 1BFEA 2VZ5A 2IWNA 1W9QA 4NMOA 4AMHA 2VRFA 3SUZA 5HEYA 2OGPA 4KFWA 3GDSA 1WF7A 2R4HA 3ID2A 3MH7A 1U3BA 2OMJA 4NMSA 3JXTA 3O46A 2FE5A 3SHWA 2IWQA 4RI0A 1UJVA 2AWXA 2M0UA 4WYTA 4NMPA 3SOEA 4NNMA 3GABA 2KOMA 4L8NA 4JOFA 5F67A 4K76A 3MH6A 1X5RA 1YBOA 1N6EA 3TSVA 1WJLA 3B76A 2K20A 3FY5A 5HFEA 4NXPA 2GZVA 3DJ1A 2JINA 1N6DA 2EEIA 3WKLA 1SOTA 4OEOA 1N6FA 4Q6SA 2Z17A 2EDZA 2LA8A 2M0ZA 4K75A 1V6BA 1M5ZA 4LMMA 2EAQA 3ID1A 3TSZA 3QE1A 3BPUA 2PNTA 3SHUA 5HF1A 3ID3A 3DJ3A 4K72A 4E34A 2P3WA 1WF8A 2KPKA 5EZ0A 2DLUA 4FGMA 1RZXA 2D92A 2KYLA 2H3MA 4NXRA 5FHTA 4REYA 3NGHA 2IWPA 5DTHA 4YYXA 5B6LA 1LCYA 4NMQA 1UM1A 5E21A 5HETA 1BE9A 2KAWA 2DKRA 4O06A 2HE4A 4NNLA 1MFGA 3GJ9A 1RY4A 2DLSA 2AWWA 1TE0A 1WHAA 3MH4A 2EV8A 1QAVA 4Q2QA 1UM7A 2JREA 2Q3GA 1X5QA 2OZFA 5HDYA 2PDZA 1VB7A 3CBYA 3NFKA 3QIKA 4KFVA 5HFDA 3AXAA 1MFLA 3PV4A 5A2PA 1MC7A 1WI2A 3QJMA 5ILBA 4JJ3A 4R2ZA 5HFBA 5JXBA 2Q9VA 4JL7A 1FC9A 1NTEA 4EDJA 3I1EA 1Q7XA 2OPGA 4FLNA 3STJA 2DAZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E35 A;  5E6P B;  1FC6 A;  2D90 A;  2OS6 A;  4JOP A;  2MX6 A;  1UJD A;  4K6Y A;  4YDP A;  1KY9 A;  2H3L A;  1KWA A;  1VAE A;  1UIT A;  5HEB A;  5HF4 A;  3OTP A;  1OBX A;  1UFX A;  1Z86 A;  2I04 A;  3EGG C;  5HFC A;  3WKM A;  4JOG A;  2E7K A;  3LNY A;  4NMT A;  1UEW A;  4OAJ A;  2M0V A;  1WI4 A;  2KRG A;  3R68 A;  4Q3H A;  5GLJ A;  2FCF A;  1UHP A;  1P1D A;  2LC7 A;  2EJY A;  2EXG A;  2YT7 A;  5F3X A;  1GQ5 A;  1V1T A;  2F5Y A;  4GVC A;  1FCF A;  4JOR A;  2DMZ A;  3DIW A;  2LUI A;  4JOK A;  3QDO A;  2OQS A;  1N7E A;  2AWU A;  4NMV A;  2EDP A;  1N7F A;  2KG2 A;  2PZD A;  3CBX A;  2EDV A;  2EEG A;  2QKV A;  2H2C A;  1OBY A;  1X45 A;  2I0I A;  3CS0 A;  2I6V A;  2YTW A;  1QAU A;  3QJN A;  2OSG A;  3PV2 A;  3CH8 A;  2CSS A;  2LC6 A;  1SOZ A;  3K82 A;  2ENO A;  5G1E A;  1W9E A;  2YUB A;  2JIL A;  1IU2 A;  1WFV A;  2KJD A;  2MHO A;  5H3J A;  1QAV B;  2KJK A;  1WG6 A;  4NXQ A;  1TP3 A;  4NMR A;  1X6D A;  3VQF A;  4WYU A;  2QBW A;  3I4W A;  2X7Z A;  2RRM A;  2AIN A;  2V90 A;  1XZ9 A;  2KV8 A;  1GQ4 A;  2JXO A;  4JOJ A;  4OEP A;  2VSV A;  2BYG A;  2PA1 A;  1QLC A;  2KA9 A;  2R3Y A;  4UU6 A;  1Q3P A;  1PDR A;  4PQW A;  4Q2N A;  1L6O A;  1TP5 A;  2EGK A;  3EGH C;  3QGL A;  1TQ3 A;  1RGW A;  3TSW A;  1FC7 A;  3CC0 A;  2CS5 A;  3HVQ C;  3GSL A;  2L4S A;  3TMH A;  3KZE A;  2K1Z A;  1IU0 A;  3OU0 A;  2YUY A;  3ZRT A;  2FN5 A;  1V5L A;  3RL7 A;  3L4F D;  1WFG A;  2JIK A;  3PDZ A;  1RGR A;  1U37 A;  4Z8J A;  3NFL A;  2VSP A;  1U38 A;  4Q2P A;  1U39 A;  2KPL A;  1Y8T A;  1B8Q A;  2G5M B;  4HOP B;  5E11 A;  1UEP A;  5D13 A;  1UEQ A;  1V5Q A;  2KL1 A;  5EYZ A;  4E3B A;  3GCO A;  4P0C A;  3DJA A;  4MPA A;  2JWE A;  3SFJ A;  4P2A B;  4HOP A;  3GDV A;  1ZOK A;  3K50 A;  1UJU A;  4H11 A;  4GHN A;  2M0T A;  2H2B A;  1N7T A;  4UU5 A;  2O2T A;  3ID4 A;  2Z9I A;  2ZPM A;  2EHR A;  3CBZ A;  4Q2O A;  1X5N A;  1R6J A;  1GM1 A;  3E17 A;  2QG1 A;  2I0L A;  1UEZ A;  1VCW A;  3GDU A;  2I4S A;  1Q3O A;  5G1D A;  2DC2 A;  1I92 A;  2M10 A;  4F8K A;  4Q6H A;  2JOA A;  2I1N A;  1NF3 C;  2D8I A;  5FB8 C;  5GND A;  1VA8 A;  2HGA A;  1WHD A;  1WH1 A;  3O5N A;  2WL7 A;  3I18 A;  2FNE A;  1N99 A;  5HJ1 A;  1Y7N A;  2L97 A;  2G2L A;  5HED A;  1OZI A;  1UF1 A;  2KOJ A;  3PS4 A;  2V1W A;  1D5G A;  2QKU A;  3QO6 A;  1VJ6 A;  3PDV A;  1W9O A;  1X8S A;  1P1E A;  1V62 A;  2DB5 A;  2KBS A;  2OCS A;  2PKT A;  5HFF A;  1IHJ A;  1K32 A;  2LOB A;  2W7R A;  2QT5 A;  2YT8 A;  2EGN A;  2CSJ A;  1WIF A;  2UZC A;  2VWR A;  3HPM A;  1ZUB A;  5I7Z A;  1Z87 A;  5E1Y A;  1I16 A;  2IWO A;  2VPH A;  1OBZ A;  1T2M A;  3R0H A;  5E22 A;  2PKU A;  2KOH A;  4GVD A;  2DM8 A;  4XHV A;  4JOH A;  2KQF A;  2EEH A;  3GCN A;  2EGO A;  2EEJ A;  3RLE A;  4Z33 A;  2REY A;  2QKT A;  3K1R A;  2HE2 A;  2KJP A;  3R69 A;  1KEF A;  3KHF A;  2ZPL A;  3DOR A;  2F0A A;  3GGE A;  3CYY A;  3VQG A;  4G69 A;  3RL8 A;  2L4T A;  2DJT A;  4N6X A;  2RCZ A;  1G9O A;  2W4F A;  3KZD A;  3LNX A;  4JOE A;  4K78 A;  3HPK A;  2M3M A;  3PV5 A;  4IC6 A;  1BFE A;  2VZ5 A;  2IWN A;  1W9Q A;  4NMO A;  4AMH A;  2VRF A;  3SUZ A;  5HEY A;  2OGP A;  4KFW A;  3GDS A;  1WF7 A;  2R4H A;  3ID2 A;  3MH7 A;  1U3B A;  2OMJ A;  4NMS A;  3JXT A;  3O46 A;  2FE5 A;  3SHW A;  2IWQ A;  4RI0 A;  1UJV A;  2AWX A;  2M0U A;  4WYT A;  4NMP A;  3SOE A;  4NNM A;  2KOM A;  4L8N A;  4JOF A;  5F67 A;  4K76 A;  3MH6 A;  1X5R A;  1YBO A;  1N6E A;  3TSV A;  1WJL A;  3B76 A;  2K20 A;  3FY5 A;  5HFE A;  4NXP A;  2GZV A;  3DJ1 A;  2JIN A;  1N6D A;  2EEI A;  3WKL A;  1SOT A;  4OEO A;  1N6F A;  4Q6S A;  2Z17 A;  2EDZ A;  2LA8 A;  2M0Z A;  4K75 A;  1V6B A;  1M5Z A;  4LMM A;  2EAQ A;  3ID1 A;  3TSZ A;  3QE1 A;  3BPU A;  2PNT A;  3SHU A;  5HF1 A;  3ID3 A;  3DJ3 A;  4K72 A;  4E34 A;  2P3W A;  1WF8 A;  2KPK A;  5EZ0 A;  2DLU A;  4FGM A;  1RZX A;  2D92 A;  2KYL A;  2H3M A;  4NXR A;  5FHT A;  4REY A;  3NGH A;  2IWP A;  5DTH A;  4YYX A;  5B6L A;  1LCY A;  4NMQ A;  1UM1 A;  5E21 A;  5HET A;  1BE9 A;  2KAW A;  2DKR A;  4O06 A;  2HE4 A;  4NNL A;  1MFG A;  3GJ9 A;  1RY4 A;  2DLS A;  2AWW A;  1TE0 A;  1WHA A;  3MH4 A;  2EV8 A;  1QAV A;  4Q2Q A;  1UM7 A;  2JRE A;  2Q3G A;  1X5Q A;  2OZF A;  5HDY A;  2PDZ A;  1VB7 A;  3CBY A;  3NFK A;  3QIK A;  4KFV A;  5HFD A;  3AXA A;  1MFL A;  3PV4 A;  5A2P A;  1MC7 A;  1WI2 A;  3QJM A;  4R2Z A;  5HFB A;  5JXB A;  2Q9V A;  4JL7 A;  1FC9 A;  1NTE A;  4EDJ A;  3I1E A;  1Q7X A;  2OPG A;  3STJ A;  2DAZ A; 
#chains in the Genus database with same CATH topology
 4E35 A;  3KDK A;  5E6P B;  1FC6 A;  2D90 A;  2OS6 A;  4JOP A;  2MX6 A;  1UJD A;  4K6Y A;  4YDP A;  1KY9 A;  2H3L A;  1KWA A;  1VAE A;  1UIT A;  5HEB A;  5HF4 A;  3OTP A;  1OBX A;  1UFX A;  1Z86 A;  2I04 A;  3EGG C;  5HFC A;  3WKM A;  4JOG A;  2E7K A;  3LNY A;  4NMT A;  1UEW A;  4OAJ A;  2M0V A;  1WI4 A;  2KRG A;  3R68 A;  4Q3H A;  5GLJ A;  2FCF A;  1UHP A;  1P1D A;  2LC7 A;  2EJY A;  2EXG A;  2YT7 A;  5F3X A;  1GQ5 A;  1V1T A;  2F5Y A;  4GVC A;  1FCF A;  4JOR A;  2DMZ A;  3DIW A;  2LUI A;  4JOK A;  3QDO A;  2OQS A;  1N7E A;  2AWU A;  4NMV A;  2EDP A;  1N7F A;  2KG2 A;  2PZD A;  3CBX A;  2EDV A;  2EEG A;  2QKV A;  2H2C A;  1OBY A;  1X45 A;  2I0I A;  3CS0 A;  2I6V A;  2YTW A;  1QAU A;  3QJN A;  2OSG A;  3PV2 A;  3CH8 A;  2CSS A;  2LC6 A;  1SOZ A;  3K82 A;  2ENO A;  5G1E A;  1W9E A;  2YUB A;  2JIL A;  1IU2 A;  4JJ0 A;  1WFV A;  2KJD A;  2MHO A;  5H3J A;  1QAV B;  2KJK A;  1WG6 A;  4NXQ A;  1TP3 A;  4NMR A;  1X6D A;  3VQF A;  4WYU A;  2QBW A;  3I4W A;  2X7Z A;  2RRM A;  2AIN A;  2V90 A;  1XZ9 A;  2KV8 A;  1GQ4 A;  2JXO A;  4JOJ A;  4OEP A;  2VSV A;  2BYG A;  2PA1 A;  1QLC A;  2KA9 A;  2R3Y A;  4UU6 A;  1Q3P A;  1PDR A;  4PQW A;  4Q2N A;  1L6O A;  1TP5 A;  2EGK A;  3EGH C;  3QGL A;  1TQ3 A;  1RGW A;  3TSW A;  1FC7 A;  3CC0 A;  2CS5 A;  3HVQ C;  3GSL A;  2L4S A;  3TMH A;  3KZE A;  2K1Z A;  1IU0 A;  3OU0 A;  2YUY A;  3ZRT A;  2FN5 A;  1V5L A;  3RL7 A;  3L4F D;  1WFG A;  2JIK A;  3PDZ A;  1RGR A;  1U37 A;  4Z8J A;  3NFL A;  2VSP A;  1U38 A;  4Q2P A;  1U39 A;  2KPL A;  1Y8T A;  1B8Q A;  2G5M B;  4HOP B;  5E11 A;  1UEP A;  5D13 A;  1UEQ A;  1V5Q A;  2KL1 A;  5EYZ A;  4E3B A;  3GCO A;  4P0C A;  3DJA A;  4MPA A;  5IL9 A;  2JWE A;  3SFJ A;  4P2A B;  4HOP A;  3GDV A;  1ZOK A;  3K50 A;  1UJU A;  4H11 A;  4GHN A;  2M0T A;  2H2B A;  1N7T A;  4UU5 A;  2O2T A;  3ID4 A;  2Z9I A;  2ZPM A;  2EHR A;  3CBZ A;  4Q2O A;  1X5N A;  1R6J A;  1GM1 A;  3E17 A;  2QG1 A;  2I0L A;  1UEZ A;  1VCW A;  3GDU A;  2I4S A;  1Q3O A;  5G1D A;  2DC2 A;  1I92 A;  2M10 A;  5B42 A;  3KDG A;  4F8K A;  4Q6H A;  2JOA A;  2I1N A;  1NF3 C;  2D8I A;  5FB8 C;  5GND A;  1VA8 A;  2HGA A;  1WHD A;  1WH1 A;  3O5N A;  2WL7 A;  3I18 A;  2FNE A;  1N99 A;  5HJ1 A;  1Y7N A;  2L97 A;  2G2L A;  5HED A;  1OZI A;  1UF1 A;  2KOJ A;  3PS4 A;  2V1W A;  1D5G A;  2QKU A;  3QO6 A;  1VJ6 A;  3PDV A;  1W9O A;  1X8S A;  1P1E A;  1V62 A;  2DB5 A;  2KBS A;  2OCS A;  2PKT A;  5HFF A;  1IHJ A;  1K32 A;  2LOB A;  2W7R A;  2QT5 A;  2YT8 A;  2EGN A;  2CSJ A;  1WIF A;  2UZC A;  2VWR A;  3HPM A;  1ZUB A;  5I7Z A;  1Z87 A;  5E1Y A;  2JSN A;  1I16 A;  2IWO A;  2VPH A;  1OBZ A;  1X9Z A;  1T2M A;  3R0H A;  5E22 A;  2PKU A;  2KOH A;  4GVD A;  2DM8 A;  4XHV A;  4JOH A;  2KQF A;  2GEF A;  2EEH A;  3GCN A;  2EGO A;  2EEJ A;  3RLE A;  4Z33 A;  2REY A;  2QKT A;  3K1R A;  2HE2 A;  2KJP A;  3R69 A;  1KEF A;  3KHF A;  2ZPL A;  3DOR A;  2F0A A;  3GGE A;  3CYY A;  3VQG A;  4G69 A;  3RL8 A;  2L4T A;  2DJT A;  3NCV A;  4N6X A;  2RCZ A;  1G9O A;  2W4F A;  3KZD A;  3LNX A;  4JOE A;  4K78 A;  3HPK A;  2M3M A;  3PV5 A;  4IC6 A;  1BFE A;  2VZ5 A;  2IWN A;  1W9Q A;  4NMO A;  4AMH A;  2VRF A;  3SUZ A;  5HEY A;  2OGP A;  4KFW A;  3GDS A;  1WF7 A;  2R4H A;  3ID2 A;  3MH7 A;  1U3B A;  2OMJ A;  4NMS A;  3JXT A;  3O46 A;  2FE5 A;  3SHW A;  2IWQ A;  4RI0 A;  1UJV A;  2AWX A;  2M0U A;  4WYT A;  4NMP A;  3SOE A;  4NNM A;  3GAB A;  2KOM A;  4L8N A;  4JOF A;  5F67 A;  4K76 A;  3MH6 A;  1X5R A;  1YBO A;  1N6E A;  3TSV A;  1WJL A;  3B76 A;  2K20 A;  3FY5 A;  5HFE A;  4NXP A;  2GZV A;  3DJ1 A;  2JIN A;  1N6D A;  2EEI A;  3WKL A;  1SOT A;  4OEO A;  1N6F A;  4Q6S A;  2Z17 A;  2EDZ A;  2LA8 A;  2M0Z A;  4K75 A;  1V6B A;  1M5Z A;  4LMM A;  2EAQ A;  3ID1 A;  3TSZ A;  3QE1 A;  3BPU A;  2PNT A;  3SHU A;  5HF1 A;  3ID3 A;  3DJ3 A;  4K72 A;  4E34 A;  2P3W A;  1WF8 A;  2KPK A;  5EZ0 A;  2DLU A;  4FGM A;  1RZX A;  2D92 A;  2KYL A;  2H3M A;  4NXR A;  5FHT A;  4REY A;  3NGH A;  2IWP A;  5DTH A;  4YYX A;  5B6L A;  1LCY A;  4NMQ A;  1UM1 A;  5E21 A;  5HET A;  1BE9 A;  2KAW A;  2DKR A;  4O06 A;  2HE4 A;  4NNL A;  1MFG A;  3GJ9 A;  1RY4 A;  2DLS A;  2AWW A;  1TE0 A;  1WHA A;  3MH4 A;  2EV8 A;  1QAV A;  4Q2Q A;  1UM7 A;  2JRE A;  2Q3G A;  1X5Q A;  2OZF A;  5HDY A;  2PDZ A;  1VB7 A;  3CBY A;  3NFK A;  3QIK A;  4KFV A;  5HFD A;  3AXA A;  1MFL A;  3PV4 A;  5A2P A;  1MC7 A;  1WI2 A;  3QJM A;  5ILB A;  4JJ3 A;  4R2Z A;  5HFB A;  5JXB A;  2Q9V A;  4JL7 A;  1FC9 A;  1NTE A;  4EDJ A;  3I1E A;  1Q7X A;  2OPG A;  4FLN A;  3STJ A;  2DAZ A; 
#chains in the Genus database with same CATH homology
 4E35 A;  3KDK A;  5E6P B;  1FC6 A;  2D90 A;  2OS6 A;  4JOP A;  2MX6 A;  1UJD A;  4K6Y A;  4YDP A;  1KY9 A;  2H3L A;  1KWA A;  1VAE A;  1UIT A;  5HEB A;  5HF4 A;  3OTP A;  1OBX A;  1UFX A;  1Z86 A;  2I04 A;  3EGG C;  5HFC A;  3WKM A;  4JOG A;  2E7K A;  3LNY A;  4NMT A;  1UEW A;  4OAJ A;  2M0V A;  1WI4 A;  2KRG A;  3R68 A;  4Q3H A;  5GLJ A;  2FCF A;  1UHP A;  1P1D A;  2LC7 A;  2EJY A;  2EXG A;  2YT7 A;  5F3X A;  1GQ5 A;  1V1T A;  2F5Y A;  4GVC A;  1FCF A;  4JOR A;  2DMZ A;  3DIW A;  2LUI A;  4JOK A;  3QDO A;  2OQS A;  1N7E A;  2AWU A;  4NMV A;  2EDP A;  1N7F A;  2KG2 A;  2PZD A;  3CBX A;  2EDV A;  2EEG A;  2QKV A;  2H2C A;  1OBY A;  1X45 A;  2I0I A;  3CS0 A;  2I6V A;  2YTW A;  1QAU A;  3QJN A;  2OSG A;  3PV2 A;  3CH8 A;  2CSS A;  2LC6 A;  1SOZ A;  3K82 A;  2ENO A;  5G1E A;  1W9E A;  2YUB A;  2JIL A;  1IU2 A;  4JJ0 A;  1WFV A;  2KJD A;  2MHO A;  5H3J A;  1QAV B;  2KJK A;  1WG6 A;  4NXQ A;  1TP3 A;  4NMR A;  1X6D A;  3VQF A;  4WYU A;  2QBW A;  3I4W A;  2X7Z A;  2RRM A;  2AIN A;  2V90 A;  1XZ9 A;  2KV8 A;  1GQ4 A;  2JXO A;  4JOJ A;  4OEP A;  2VSV A;  2BYG A;  2PA1 A;  1QLC A;  2KA9 A;  2R3Y A;  4UU6 A;  1Q3P A;  1PDR A;  4PQW A;  4Q2N A;  1L6O A;  1TP5 A;  2EGK A;  3EGH C;  3QGL A;  1TQ3 A;  1RGW A;  3TSW A;  1FC7 A;  3CC0 A;  2CS5 A;  3HVQ C;  3GSL A;  2L4S A;  3TMH A;  3KZE A;  2K1Z A;  1IU0 A;  3OU0 A;  2YUY A;  3ZRT A;  2FN5 A;  1V5L A;  3RL7 A;  3L4F D;  1WFG A;  2JIK A;  3PDZ A;  1RGR A;  1U37 A;  4Z8J A;  3NFL A;  2VSP A;  1U38 A;  4Q2P A;  1U39 A;  2KPL A;  1Y8T A;  1B8Q A;  2G5M B;  4HOP B;  5E11 A;  1UEP A;  5D13 A;  1UEQ A;  1V5Q A;  2KL1 A;  5EYZ A;  4E3B A;  3GCO A;  4P0C A;  3DJA A;  4MPA A;  5IL9 A;  2JWE A;  3SFJ A;  4P2A B;  4HOP A;  3GDV A;  1ZOK A;  3K50 A;  1UJU A;  4H11 A;  4GHN A;  2M0T A;  2H2B A;  1N7T A;  4UU5 A;  2O2T A;  3ID4 A;  2Z9I A;  2ZPM A;  2EHR A;  3CBZ A;  4Q2O A;  1X5N A;  1R6J A;  1GM1 A;  3E17 A;  2QG1 A;  2I0L A;  1UEZ A;  1VCW A;  3GDU A;  2I4S A;  1Q3O A;  5G1D A;  2DC2 A;  1I92 A;  2M10 A;  5B42 A;  3KDG A;  4F8K A;  4Q6H A;  2JOA A;  2I1N A;  1NF3 C;  2D8I A;  5FB8 C;  5GND A;  1VA8 A;  2HGA A;  1WHD A;  1WH1 A;  3O5N A;  2WL7 A;  3I18 A;  2FNE A;  1N99 A;  5HJ1 A;  1Y7N A;  2L97 A;  2G2L A;  5HED A;  1OZI A;  1UF1 A;  2KOJ A;  3PS4 A;  2V1W A;  1D5G A;  2QKU A;  3QO6 A;  1VJ6 A;  3PDV A;  1W9O A;  1X8S A;  1P1E A;  1V62 A;  2DB5 A;  2KBS A;  2OCS A;  2PKT A;  5HFF A;  1IHJ A;  1K32 A;  2LOB A;  2W7R A;  2QT5 A;  2YT8 A;  2EGN A;  2CSJ A;  1WIF A;  2UZC A;  2VWR A;  3HPM A;  1ZUB A;  5I7Z A;  1Z87 A;  5E1Y A;  2JSN A;  1I16 A;  2IWO A;  2VPH A;  1OBZ A;  1X9Z A;  1T2M A;  3R0H A;  5E22 A;  2PKU A;  2KOH A;  4GVD A;  2DM8 A;  4XHV A;  4JOH A;  2KQF A;  2GEF A;  2EEH A;  3GCN A;  2EGO A;  2EEJ A;  3RLE A;  4Z33 A;  2REY A;  2QKT A;  3K1R A;  2HE2 A;  2KJP A;  3R69 A;  1KEF A;  3KHF A;  2ZPL A;  3DOR A;  2F0A A;  3GGE A;  3CYY A;  3VQG A;  4G69 A;  3RL8 A;  2L4T A;  2DJT A;  3NCV A;  4N6X A;  2RCZ A;  1G9O A;  2W4F A;  3KZD A;  3LNX A;  4JOE A;  4K78 A;  3HPK A;  2M3M A;  3PV5 A;  4IC6 A;  1BFE A;  2VZ5 A;  2IWN A;  1W9Q A;  4NMO A;  4AMH A;  2VRF A;  3SUZ A;  5HEY A;  2OGP A;  4KFW A;  3GDS A;  1WF7 A;  2R4H A;  3ID2 A;  3MH7 A;  1U3B A;  2OMJ A;  4NMS A;  3JXT A;  3O46 A;  2FE5 A;  3SHW A;  2IWQ A;  4RI0 A;  1UJV A;  2AWX A;  2M0U A;  4WYT A;  4NMP A;  3SOE A;  4NNM A;  3GAB A;  2KOM A;  4L8N A;  4JOF A;  5F67 A;  4K76 A;  3MH6 A;  1X5R A;  1YBO A;  1N6E A;  3TSV A;  1WJL A;  3B76 A;  2K20 A;  3FY5 A;  5HFE A;  4NXP A;  2GZV A;  3DJ1 A;  2JIN A;  1N6D A;  2EEI A;  3WKL A;  1SOT A;  4OEO A;  1N6F A;  4Q6S A;  2Z17 A;  2EDZ A;  2LA8 A;  2M0Z A;  4K75 A;  1V6B A;  1M5Z A;  4LMM A;  2EAQ A;  3ID1 A;  3TSZ A;  3QE1 A;  3BPU A;  2PNT A;  3SHU A;  5HF1 A;  3ID3 A;  3DJ3 A;  4K72 A;  4E34 A;  2P3W A;  1WF8 A;  2KPK A;  5EZ0 A;  2DLU A;  4FGM A;  1RZX A;  2D92 A;  2KYL A;  2H3M A;  4NXR A;  5FHT A;  4REY A;  3NGH A;  2IWP A;  5DTH A;  4YYX A;  5B6L A;  1LCY A;  4NMQ A;  1UM1 A;  5E21 A;  5HET A;  1BE9 A;  2KAW A;  2DKR A;  4O06 A;  2HE4 A;  4NNL A;  1MFG A;  3GJ9 A;  1RY4 A;  2DLS A;  2AWW A;  1TE0 A;  1WHA A;  3MH4 A;  2EV8 A;  1QAV A;  4Q2Q A;  1UM7 A;  2JRE A;  2Q3G A;  1X5Q A;  2OZF A;  5HDY A;  2PDZ A;  1VB7 A;  3CBY A;  3NFK A;  3QIK A;  4KFV A;  5HFD A;  3AXA A;  1MFL A;  3PV4 A;  5A2P A;  1MC7 A;  1WI2 A;  3QJM A;  5ILB A;  4JJ3 A;  4R2Z A;  5HFB A;  5JXB A;  2Q9V A;  4JL7 A;  1FC9 A;  1NTE A;  4EDJ A;  3I1E A;  1Q7X A;  2OPG A;  4FLN A;  3STJ A;  2DAZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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