5E22A

The second pdz domain of ligand of numb protein x 2 in the presence of an electric field of ~1 mv/cm along the crystallographic x axis, with eightfold extrapolation of structure factor differences.
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
95
structure length
95
Chain Sequence
SMEILQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQIIQASGERVNLTIARPGKPEIEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Electric-field-stimulated protein mechanics.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Ligand of Numb protein X 2
total genus 20
structure length 95
sequence length 95
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00595 PDZ PDZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.42.10 Mainly Beta Roll Pdz3 Domain Pdz3 Domain 5e22A00
2R4HA 1MFGA 4WYUA 2JILA 2QKVA 2DM8A 4K72A 5E6PB 1V62A 1KWAA 3GDUA 4F8KA 1U3BA 3GDSA 1W9OA 4FGMA 1WF7A 3OU0A 1UHPA 4KFVA 1RGWA 3WKMA 2KPLA 4H11A 2YT8A 1FC7A 3TMHA 2W4FA 2EEIA 3PDVA 1OBYA 1V5QA 2KG2A 4MPAA 1WHDA 4NXQA 3SOEA 2DLUA 3GCOA 2M10A 2M0TA 1N6FA 4Z8JA 3PV2A 1N7EA 1YBOA 3TSWA 1UM1A 3I1EA 2EJYA 1G9OA 1I16A 2EGKA 2M0UA 3LNYA 1WFGA 1QAVB 2OSGA 1RY4A 2LA8A 4UU6A 2OGPA 3R69A 1FC6A 5HF1A 1U38A 2REYA 4JL7A 4OEOA 2EEJA 2V90A 4REYA 2KYLA 5G1DA 2D92A 1VJ6A 2KJKA 1WIFA 1MC7A 2KJPA 3K1RA 2RRMA 2OS6A 3PV4A 2YT7A 3CBZA 2UZCA 2Z9IA 2OZFA 2ZPLA 3CBYA 1RZXA 2AWXA 2PKUA 3DIWA 3QIKA 4P2AB 4NXPA 1WI2A 4NMVA 2I0IA 2ENOA 4JOEA 1UEPA 4YYXA 1UM7A 3EGHC 2F5YA 3DJAA 3GJ9A 1I92A 2P3WA 1OBXA 3HPKA 4OEPA 2V1WA 1N7FA 5F67A 3I4WA 2M3MA 2L97A 2PKTA 5HFBA 3QJMA 3O5NA 4JORA 1WJLA 3OTPA 4HOPB 1UEWA 5HJ1A 3AXAA 2M0ZA 2LC6A 5HF4A 1WF8A 1WHAA 2FCFA 5D13A 2AWUA 2YTWA 1N7TA 4K78A 2VPHA 5HEYA 3WKLA 1SOZA 2EDVA 2QBWA 4NMPA 2KV8A 1L6OA 3QGLA 3VQGA 3K50A 1GM1A 3NFLA 2DLSA 2YUBA 1V1TA 2H2CA 4GVCA 4NMOA 4L8NA 2KA9A 2I6VA 2DMZA 3I18A 2KJDA 4O06A 5HFDA 4NNMA 2R3YA 3NFKA 1GQ5A 2H3LA 2OPGA 3KZDA 2AINA 1WG6A 2X7ZA 2KRGA 2JWEA 4K76A 1M5ZA 2K20A 4RI0A 1QLCA 2K1ZA 1VAEA 2FN5A 2GZVA 1KEFA 3CYYA 2DB5A 1W9QA 3NGHA 2HE4A 3DORA 1FCFA 1N6DA 4JOHA 4IC6A 4R2ZA 1BFEA 2I04A 2IWNA 2EGNA 3FY5A 1UITA 4JOFA 3CH8A 3CBXA 1UJUA 1Q3PA 1X8SA 1VCWA 4Q2QA 3RLEA 3SFJA 1TE0A 5E21A 5EZ0A 2F0AA 3GDVA 3O46A 1BE9A 2KOJA 1QAVA 2HE2A 2KOHA 1V5LA 2PA1A 1VB7A 3SHUA 3SUZA 1OBZA 2KAWA 1LCYA 3K82A 3TSVA 4NMRA 2MX6A 1UFXA 4OAJA 2PDZA 3RL7A 2QG1A 2EEHA 2DC2A 2CSSA 2VWRA 3ID2A 3QE1A 3ZRTA 4Q3HA 2KPKA 3GSLA 1KY9A 4GVDA 3VQFA 5GLJA 3ID3A 3KHFA 4E3BA 1V6BA 4E34A 2Z17A 2IWPA 3ID4A 4GHNA 4Q2NA 3QO6A 1IHJA 2JINA 3PDZA 2E7KA 4NNLA 4G69A 2M0VA 1WFVA 2ZPMA 2CSJA 4JOGA 5E1YA 5EYZA 1UF1A 1NF3C 2LC7A 4LMMA 4K6YA 3DJ3A 5F3XA 3CS0A 1U37A 4Q2OA 4HOPA 5E11A 1IU0A 2KL1A 1TQ3A 2MHOA 5E22A 5G1EA 4YDPA 2QKUA 1UEQA 2IWOA 3MH4A 3MH7A 1P1DA 2AWWA 2O2TA 5HFFA 2Q9VA 1RGRA 1T2MA 1D5GA 1IU2A 3HVQC 5JXBA 3QJNA 4JOPA 4JOJA 4E35A 2EGOA 3QDOA 3LNXA 2VSVA 2OQSA 2W7RA 2KOMA 1Y7NA 2VRFA 2EEGA 2FE5A 2L4SA 4XHVA 3TSZA 2FNEA 3SHWA 1N99A 2JIKA 1SOTA 5HEDA 5I7ZA 4K75A 5A2PA 2OCSA 3HPMA 2QKTA 2BYGA 2JOAA 5HDYA 3EGGC 2D8IA 5HFEA 2WL7A 1X5RA 2JREA 2D90A 3GGEA 2EAQA 4EDJA 1N6EA 4Q6SA 3E17A 5DTHA 4Q6HA 2VSPA 3STJA 2PNTA 1Q3OA 2L4TA 2KQFA 1QAUA 2HGAA 1Z87A 3GCNA 1TP5A 1ZOKA 4Z33A 1X5NA 1K32A 2EXGA 2EDPA 2VZ5A 2LOBA 3BPUA 3R68A 1X45A 1Y8TA 2EDZA 2H3MA 4NMTA 1U39A 3PV5A 3CC0A 1XZ9A 2LUIA 1UJVA 2DJTA 2H2BA 5HETA 1PDRA 1ZUBA 4AMHA 1VA8A 4N6XA 2CS5A 2DAZA 2JXOA 5HEBA 3R0HA 1P1EA 1OZIA 3DJ1A 5FHTA 2I0LA 3ID1A 1X6DA 1Z86A 4JOKA 1GQ4A 1WH1A 5FB8C 4WYTA 2YUYA 5B6LA 2G5MB 4P0CA 1MFLA 2I4SA 4UU5A 1UEZA 4PQWA 2QT5A 5HFCA 4NXRA 2PZDA 3B76A 1FC9A 2I1NA 2EV8A 2RCZA 3JXTA 5GNDA 2DKRA 3MH6A 5H3JA 2IWQA 4NMSA 1NTEA 2Q3GA 3PS4A 3RL8A 1WI4A 1TP3A 2OMJA 3L4FD 4KFWA 2EHRA 2G2LA 3KZEA 4NMQA 1UJDA 2KBSA 1Q7XA 1W9EA 1X5QA 1B8QA 4Q2PA 1R6JA
chains in the Genus database with same CATH superfamily
2R4HA 1MFGA 4WYUA 2JILA 2QKVA 2DM8A 4K72A 5E6PB 1V62A 1KWAA 3GDUA 4F8KA 1U3BA 3GDSA 1W9OA 4FGMA 1WF7A 3OU0A 1UHPA 4KFVA 1RGWA 3WKMA 2KPLA 4H11A 2YT8A 1FC7A 3TMHA 2W4FA 2EEIA 3PDVA 1OBYA 1V5QA 2GEFA 2KG2A 4MPAA 1WHDA 4NXQA 3SOEA 2DLUA 3GCOA 2M10A 2M0TA 1N6FA 4Z8JA 3PV2A 1N7EA 1YBOA 3TSWA 1UM1A 3I1EA 2EJYA 1G9OA 1I16A 2EGKA 2M0UA 3LNYA 1WFGA 1QAVB 2OSGA 1RY4A 2LA8A 4UU6A 2OGPA 3R69A 1FC6A 5HF1A 1U38A 2REYA 4JL7A 4OEOA 2EEJA 2V90A 4REYA 2KYLA 5G1DA 2D92A 1VJ6A 2KJKA 1WIFA 1MC7A 2KJPA 3K1RA 2RRMA 2OS6A 3PV4A 2YT7A 3CBZA 2UZCA 2Z9IA 2OZFA 2ZPLA 3CBYA 1RZXA 2AWXA 2PKUA 3DIWA 3QIKA 4P2AB 4NXPA 1WI2A 4NMVA 2I0IA 2ENOA 4JOEA 1UEPA 4YYXA 1UM7A 3EGHC 2F5YA 3DJAA 3GJ9A 1I92A 2P3WA 1OBXA 3HPKA 4OEPA 2V1WA 1N7FA 5F67A 3I4WA 2M3MA 2L97A 2PKTA 5HFBA 3QJMA 3O5NA 4JORA 1WJLA 3OTPA 4HOPB 1UEWA 5HJ1A 3AXAA 2M0ZA 2LC6A 5HF4A 1WF8A 1WHAA 2FCFA 5D13A 2AWUA 2YTWA 1N7TA 4K78A 2VPHA 5HEYA 3WKLA 1SOZA 2EDVA 2QBWA 4NMPA 2KV8A 1L6OA 3QGLA 3VQGA 3K50A 1GM1A 3NFLA 2DLSA 2YUBA 1V1TA 2H2CA 4GVCA 4NMOA 4L8NA 1X9ZA 2I6VA 2KA9A 2DMZA 3I18A 2KJDA 4O06A 5HFDA 4NNMA 2R3YA 3NFKA 1GQ5A 2H3LA 2OPGA 3KZDA 2AINA 1WG6A 2X7ZA 2KRGA 2JWEA 4K76A 1M5ZA 2K20A 4RI0A 1QLCA 2K1ZA 1VAEA 2FN5A 2GZVA 1KEFA 3CYYA 2DB5A 1W9QA 3NGHA 2HE4A 3DORA 1FCFA 1N6DA 4JOHA 4IC6A 4R2ZA 1BFEA 2I04A 2IWNA 2EGNA 3FY5A 5IL9A 1UITA 4JOFA 3CH8A 3CBXA 1UJUA 1Q3PA 1X8SA 4FLNA 1VCWA 4Q2QA 3RLEA 3SFJA 1TE0A 5E21A 5EZ0A 5B42A 2F0AA 3GDVA 3O46A 1BE9A 2KOJA 1QAVA 2HE2A 2KOHA 1V5LA 2PA1A 1VB7A 3SHUA 3SUZA 1OBZA 2KAWA 1LCYA 3K82A 3TSVA 4NMRA 2MX6A 1UFXA 4OAJA 2PDZA 3RL7A 2QG1A 2EEHA 2DC2A 2CSSA 2VWRA 3ID2A 3QE1A 3ZRTA 4Q3HA 2KPKA 3GSLA 1KY9A 4GVDA 3VQFA 5GLJA 3ID3A 3KHFA 4E3BA 1V6BA 4E34A 2Z17A 2IWPA 3ID4A 4GHNA 4Q2NA 3QO6A 1IHJA 2JINA 3PDZA 2E7KA 4NNLA 4G69A 2M0VA 1WFVA 2ZPMA 2CSJA 4JOGA 5E1YA 5EYZA 1UF1A 1NF3C 2LC7A 4LMMA 4K6YA 3DJ3A 5F3XA 3CS0A 1U37A 4Q2OA 4HOPA 5E11A 1IU0A 2KL1A 1TQ3A 2MHOA 5E22A 5G1EA 4YDPA 2QKUA 1UEQA 2IWOA 3MH4A 3MH7A 1P1DA 2AWWA 2O2TA 5HFFA 2Q9VA 1RGRA 1T2MA 1D5GA 1IU2A 3HVQC 5JXBA 3QJNA 4JOPA 4JOJA 4E35A 2EGOA 3QDOA 3LNXA 2VSVA 2OQSA 2W7RA 2KOMA 1Y7NA 2VRFA 2EEGA 2FE5A 2L4SA 4JJ3A 4XHVA 3TSZA 2FNEA 3SHWA 1N99A 2JIKA 1SOTA 5HEDA 5I7ZA 4K75A 5A2PA 2OCSA 3HPMA 2QKTA 2BYGA 2JOAA 5HDYA 3EGGC 2D8IA 5HFEA 2WL7A 1X5RA 3KDKA 2JREA 2D90A 3GGEA 2EAQA 4EDJA 1N6EA 4Q6SA 3E17A 5DTHA 4Q6HA 2VSPA 3STJA 2PNTA 5ILBA 1Q3OA 2L4TA 2KQFA 1QAUA 2HGAA 1Z87A 3GCNA 1TP5A 1ZOKA 4Z33A 1X5NA 1K32A 2EXGA 2EDPA 2VZ5A 2LOBA 2JSNA 3BPUA 3R68A 1X45A 1Y8TA 2EDZA 4JJ0A 2H3MA 4NMTA 1U39A 3PV5A 3CC0A 1XZ9A 2LUIA 1UJVA 2DJTA 2H2BA 5HETA 1PDRA 1ZUBA 4AMHA 1VA8A 4N6XA 2CS5A 2DAZA 3NCVA 2JXOA 5HEBA 3R0HA 1P1EA 1OZIA 3DJ1A 3GABA 2I0LA 3ID1A 1X6DA 1Z86A 4JOKA 5FHTA 1GQ4A 1WH1A 5FB8C 4WYTA 2YUYA 5B6LA 2G5MB 4P0CA 1MFLA 2I4SA 4UU5A 1UEZA 4PQWA 2QT5A 5HFCA 4NXRA 2PZDA 3B76A 1FC9A 2I1NA 2EV8A 2RCZA 3JXTA 5GNDA 2DKRA 3MH6A 5H3JA 2IWQA 4NMSA 1NTEA 2Q3GA 3PS4A 3RL8A 1WI4A 1TP3A 2OMJA 3L4FD 4KFWA 2EHRA 2G2LA 3KZEA 4NMQA 1UJDA 2KBSA 1Q7XA 1W9EA 3KDGA 1X5QA 1B8QA 4Q2PA 1R6JA
chains in the Genus database with same CATH topology
2R4HA 1MFGA 4WYUA 2JILA 2QKVA 2DM8A 4K72A 5E6PB 1V62A 1KWAA 3GDUA 4F8KA 1U3BA 3GDSA 1W9OA 4FGMA 1WF7A 3OU0A 1UHPA 4KFVA 1RGWA 3WKMA 2KPLA 4H11A 2YT8A 1FC7A 3TMHA 2W4FA 2EEIA 3PDVA 1OBYA 1V5QA 2GEFA 2KG2A 4MPAA 1WHDA 4NXQA 3SOEA 2DLUA 3GCOA 2M10A 2M0TA 1N6FA 4Z8JA 3PV2A 1N7EA 1YBOA 3TSWA 1UM1A 3I1EA 2EJYA 1G9OA 1I16A 2EGKA 2M0UA 3LNYA 1WFGA 1QAVB 2OSGA 1RY4A 2LA8A 4UU6A 2OGPA 3R69A 1FC6A 5HF1A 1U38A 2REYA 4JL7A 4OEOA 2EEJA 2V90A 4REYA 2KYLA 5G1DA 2D92A 1VJ6A 2KJKA 1WIFA 1MC7A 2KJPA 3K1RA 2RRMA 2OS6A 3PV4A 2YT7A 3CBZA 2UZCA 2Z9IA 2OZFA 2ZPLA 3CBYA 1RZXA 2AWXA 2PKUA 3DIWA 3QIKA 4P2AB 4NXPA 1WI2A 4NMVA 2I0IA 2ENOA 4JOEA 1UEPA 4YYXA 1UM7A 3EGHC 2F5YA 3DJAA 3GJ9A 1I92A 2P3WA 1OBXA 3HPKA 4OEPA 2V1WA 1N7FA 5F67A 3I4WA 2M3MA 2L97A 2PKTA 5HFBA 3QJMA 3O5NA 4JORA 1WJLA 3OTPA 4HOPB 1UEWA 5HJ1A 3AXAA 2M0ZA 2LC6A 5HF4A 1WF8A 1WHAA 2FCFA 5D13A 2AWUA 2YTWA 1N7TA 4K78A 2VPHA 5HEYA 3WKLA 1SOZA 2EDVA 2QBWA 4NMPA 2KV8A 1L6OA 3QGLA 3VQGA 3K50A 1GM1A 3NFLA 2DLSA 2YUBA 1V1TA 2H2CA 4GVCA 4NMOA 4L8NA 1X9ZA 2I6VA 2KA9A 2DMZA 3I18A 2KJDA 4O06A 5HFDA 4NNMA 2R3YA 3NFKA 1GQ5A 2H3LA 2OPGA 3KZDA 2AINA 1WG6A 2X7ZA 2KRGA 2JWEA 4K76A 1M5ZA 2K20A 4RI0A 1QLCA 2K1ZA 1VAEA 2FN5A 2GZVA 1KEFA 3CYYA 2DB5A 1W9QA 3NGHA 2HE4A 3DORA 1FCFA 1N6DA 4JOHA 4IC6A 4R2ZA 1BFEA 2I04A 2IWNA 2EGNA 3FY5A 5IL9A 1UITA 4JOFA 3CH8A 3CBXA 1UJUA 1Q3PA 1X8SA 4FLNA 1VCWA 4Q2QA 3RLEA 3SFJA 1TE0A 5E21A 5EZ0A 5B42A 2F0AA 3GDVA 3O46A 1BE9A 2KOJA 1QAVA 2HE2A 2KOHA 1V5LA 2PA1A 1VB7A 3SHUA 3SUZA 1OBZA 2KAWA 1LCYA 3K82A 3TSVA 4NMRA 2MX6A 1UFXA 4OAJA 2PDZA 3RL7A 2QG1A 2EEHA 2DC2A 2CSSA 2VWRA 3ID2A 3QE1A 3ZRTA 4Q3HA 2KPKA 3GSLA 1KY9A 4GVDA 3VQFA 5GLJA 3ID3A 3KHFA 4E3BA 1V6BA 4E34A 2Z17A 2IWPA 3ID4A 4GHNA 4Q2NA 3QO6A 1IHJA 2JINA 3PDZA 2E7KA 4NNLA 4G69A 2M0VA 1WFVA 2ZPMA 2CSJA 4JOGA 5E1YA 5EYZA 1UF1A 1NF3C 2LC7A 4LMMA 4K6YA 3DJ3A 5F3XA 3CS0A 1U37A 4Q2OA 4HOPA 5E11A 1IU0A 2KL1A 1TQ3A 2MHOA 5E22A 5G1EA 4YDPA 2QKUA 1UEQA 2IWOA 3MH4A 3MH7A 1P1DA 2AWWA 2O2TA 5HFFA 2Q9VA 1RGRA 1T2MA 1D5GA 1IU2A 3HVQC 5JXBA 3QJNA 4JOPA 4JOJA 4E35A 2EGOA 3QDOA 3LNXA 2VSVA 2OQSA 2W7RA 2KOMA 1Y7NA 2VRFA 2EEGA 2FE5A 2L4SA 4JJ3A 4XHVA 3TSZA 2FNEA 3SHWA 1N99A 2JIKA 1SOTA 5HEDA 5I7ZA 4K75A 5A2PA 2OCSA 3HPMA 2QKTA 2BYGA 2JOAA 5HDYA 3EGGC 2D8IA 5HFEA 2WL7A 1X5RA 3KDKA 2JREA 2D90A 3GGEA 2EAQA 4EDJA 1N6EA 4Q6SA 3E17A 5DTHA 4Q6HA 2VSPA 3STJA 2PNTA 5ILBA 1Q3OA 2L4TA 2KQFA 1QAUA 2HGAA 1Z87A 3GCNA 1TP5A 1ZOKA 4Z33A 1X5NA 1K32A 2EXGA 2EDPA 2VZ5A 2LOBA 2JSNA 3BPUA 3R68A 1X45A 1Y8TA 2EDZA 4JJ0A 2H3MA 4NMTA 1U39A 3PV5A 3CC0A 1XZ9A 2LUIA 1UJVA 2DJTA 2H2BA 5HETA 1PDRA 1ZUBA 4AMHA 1VA8A 4N6XA 2CS5A 2DAZA 3NCVA 2JXOA 5HEBA 3R0HA 1P1EA 1OZIA 3DJ1A 3GABA 2I0LA 3ID1A 1X6DA 1Z86A 4JOKA 5FHTA 1GQ4A 1WH1A 5FB8C 4WYTA 2YUYA 5B6LA 2G5MB 4P0CA 1MFLA 2I4SA 4UU5A 1UEZA 4PQWA 2QT5A 5HFCA 4NXRA 2PZDA 3B76A 1FC9A 2I1NA 2EV8A 2RCZA 3JXTA 5GNDA 2DKRA 3MH6A 5H3JA 2IWQA 4NMSA 1NTEA 2Q3GA 3PS4A 3RL8A 1WI4A 1TP3A 2OMJA 3L4FD 4KFWA 2EHRA 2G2LA 3KZEA 4NMQA 1UJDA 2KBSA 1Q7XA 1W9EA 3KDGA 1X5QA 1B8QA 4Q2PA 1R6JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R4H A;  1MFG A;  4WYU A;  2JIL A;  2QKV A;  2DM8 A;  4K72 A;  5E6P B;  1V62 A;  1KWA A;  3GDU A;  4F8K A;  1U3B A;  3GDS A;  1W9O A;  4FGM A;  1WF7 A;  3OU0 A;  1UHP A;  4KFV A;  1RGW A;  3WKM A;  2KPL A;  4H11 A;  2YT8 A;  1FC7 A;  3TMH A;  2W4F A;  2EEI A;  3PDV A;  1OBY A;  1V5Q A;  2KG2 A;  4MPA A;  1WHD A;  4NXQ A;  3SOE A;  2DLU A;  3GCO A;  2M10 A;  2M0T A;  1N6F A;  4Z8J A;  3PV2 A;  1N7E A;  1YBO A;  3TSW A;  1UM1 A;  3I1E A;  2EJY A;  1G9O A;  1I16 A;  2EGK A;  2M0U A;  3LNY A;  1WFG A;  1QAV B;  2OSG A;  1RY4 A;  2LA8 A;  4UU6 A;  2OGP A;  3R69 A;  1FC6 A;  5HF1 A;  1U38 A;  2REY A;  4JL7 A;  4OEO A;  2EEJ A;  2V90 A;  4REY A;  2KYL A;  5G1D A;  2D92 A;  1VJ6 A;  2KJK A;  1WIF A;  1MC7 A;  2KJP A;  3K1R A;  2RRM A;  2OS6 A;  3PV4 A;  2YT7 A;  3CBZ A;  2UZC A;  2Z9I A;  2OZF A;  2ZPL A;  3CBY A;  1RZX A;  2AWX A;  2PKU A;  3DIW A;  3QIK A;  4P2A B;  4NXP A;  1WI2 A;  4NMV A;  2I0I A;  2ENO A;  4JOE A;  1UEP A;  4YYX A;  1UM7 A;  3EGH C;  2F5Y A;  3DJA A;  3GJ9 A;  1I92 A;  2P3W A;  1OBX A;  3HPK A;  4OEP A;  2V1W A;  1N7F A;  5F67 A;  3I4W A;  2M3M A;  2L97 A;  2PKT A;  5HFB A;  3QJM A;  3O5N A;  4JOR A;  1WJL A;  3OTP A;  4HOP B;  1UEW A;  5HJ1 A;  3AXA A;  2M0Z A;  2LC6 A;  5HF4 A;  1WF8 A;  1WHA A;  2FCF A;  5D13 A;  2AWU A;  2YTW A;  1N7T A;  4K78 A;  2VPH A;  5HEY A;  3WKL A;  1SOZ A;  2EDV A;  2QBW A;  4NMP A;  2KV8 A;  1L6O A;  3QGL A;  3VQG A;  3K50 A;  1GM1 A;  3NFL A;  2DLS A;  2YUB A;  1V1T A;  2H2C A;  4GVC A;  4NMO A;  4L8N A;  2KA9 A;  2I6V A;  2DMZ A;  3I18 A;  2KJD A;  4O06 A;  5HFD A;  4NNM A;  2R3Y A;  3NFK A;  1GQ5 A;  2H3L A;  2OPG A;  3KZD A;  2AIN A;  1WG6 A;  2X7Z A;  2KRG A;  2JWE A;  4K76 A;  1M5Z A;  2K20 A;  4RI0 A;  1QLC A;  2K1Z A;  1VAE A;  2FN5 A;  2GZV A;  1KEF A;  3CYY A;  2DB5 A;  1W9Q A;  3NGH A;  2HE4 A;  3DOR A;  1FCF A;  1N6D A;  4JOH A;  4IC6 A;  4R2Z A;  1BFE A;  2I04 A;  2IWN A;  2EGN A;  3FY5 A;  1UIT A;  4JOF A;  3CH8 A;  3CBX A;  1UJU A;  1Q3P A;  1X8S A;  1VCW A;  4Q2Q A;  3RLE A;  3SFJ A;  1TE0 A;  5E21 A;  5EZ0 A;  2F0A A;  3GDV A;  3O46 A;  1BE9 A;  2KOJ A;  1QAV A;  2HE2 A;  2KOH A;  1V5L A;  2PA1 A;  1VB7 A;  3SHU A;  3SUZ A;  1OBZ A;  2KAW A;  1LCY A;  3K82 A;  3TSV A;  4NMR A;  2MX6 A;  1UFX A;  4OAJ A;  2PDZ A;  3RL7 A;  2QG1 A;  2EEH A;  2DC2 A;  2CSS A;  2VWR A;  3ID2 A;  3QE1 A;  3ZRT A;  4Q3H A;  2KPK A;  3GSL A;  1KY9 A;  4GVD A;  3VQF A;  5GLJ A;  3ID3 A;  3KHF A;  4E3B A;  1V6B A;  4E34 A;  2Z17 A;  2IWP A;  3ID4 A;  4GHN A;  4Q2N A;  3QO6 A;  1IHJ A;  2JIN A;  3PDZ A;  2E7K A;  4NNL A;  4G69 A;  2M0V A;  1WFV A;  2ZPM A;  2CSJ A;  4JOG A;  5E1Y A;  5EYZ A;  1UF1 A;  1NF3 C;  2LC7 A;  4LMM A;  4K6Y A;  3DJ3 A;  5F3X A;  3CS0 A;  1U37 A;  4Q2O A;  4HOP A;  5E11 A;  1IU0 A;  2KL1 A;  1TQ3 A;  2MHO A;  5E22 A;  5G1E A;  4YDP A;  2QKU A;  1UEQ A;  2IWO A;  3MH4 A;  3MH7 A;  1P1D A;  2AWW A;  2O2T A;  5HFF A;  2Q9V A;  1RGR A;  1T2M A;  1D5G A;  1IU2 A;  3HVQ C;  5JXB A;  3QJN A;  4JOP A;  4JOJ A;  4E35 A;  2EGO A;  3QDO A;  3LNX A;  2VSV A;  2OQS A;  2W7R A;  2KOM A;  1Y7N A;  2VRF A;  2EEG A;  2FE5 A;  2L4S A;  4XHV A;  3TSZ A;  2FNE A;  3SHW A;  1N99 A;  2JIK A;  1SOT A;  5HED A;  5I7Z A;  4K75 A;  5A2P A;  2OCS A;  3HPM A;  2QKT A;  2BYG A;  2JOA A;  5HDY A;  3EGG C;  2D8I A;  5HFE A;  2WL7 A;  1X5R A;  2JRE A;  2D90 A;  3GGE A;  2EAQ A;  4EDJ A;  1N6E A;  4Q6S A;  3E17 A;  5DTH A;  4Q6H A;  2VSP A;  3STJ A;  2PNT A;  1Q3O A;  2L4T A;  2KQF A;  1QAU A;  2HGA A;  1Z87 A;  3GCN A;  1TP5 A;  1ZOK A;  4Z33 A;  1X5N A;  1K32 A;  2EXG A;  2EDP A;  2VZ5 A;  2LOB A;  3BPU A;  3R68 A;  1X45 A;  1Y8T A;  2EDZ A;  2H3M A;  4NMT A;  1U39 A;  3PV5 A;  3CC0 A;  1XZ9 A;  2LUI A;  1UJV A;  2DJT A;  2H2B A;  5HET A;  1PDR A;  1ZUB A;  4AMH A;  1VA8 A;  4N6X A;  2CS5 A;  2DAZ A;  2JXO A;  5HEB A;  3R0H A;  1P1E A;  1OZI A;  3DJ1 A;  5FHT A;  2I0L A;  3ID1 A;  1X6D A;  1Z86 A;  4JOK A;  1GQ4 A;  1WH1 A;  5FB8 C;  4WYT A;  2YUY A;  5B6L A;  2G5M B;  4P0C A;  1MFL A;  2I4S A;  4UU5 A;  1UEZ A;  4PQW A;  2QT5 A;  5HFC A;  4NXR A;  2PZD A;  3B76 A;  1FC9 A;  2I1N A;  2EV8 A;  2RCZ A;  3JXT A;  5GND A;  2DKR A;  3MH6 A;  5H3J A;  2IWQ A;  4NMS A;  1NTE A;  2Q3G A;  3PS4 A;  3RL8 A;  1WI4 A;  1TP3 A;  2OMJ A;  3L4F D;  4KFW A;  2EHR A;  2G2L A;  3KZE A;  4NMQ A;  1UJD A;  2KBS A;  1Q7X A;  1W9E A;  1X5Q A;  1B8Q A;  4Q2P A;  1R6J A; 
#chains in the Genus database with same CATH topology
 2R4H A;  1MFG A;  4WYU A;  2JIL A;  2QKV A;  2DM8 A;  4K72 A;  5E6P B;  1V62 A;  1KWA A;  3GDU A;  4F8K A;  1U3B A;  3GDS A;  1W9O A;  4FGM A;  1WF7 A;  3OU0 A;  1UHP A;  4KFV A;  1RGW A;  3WKM A;  2KPL A;  4H11 A;  2YT8 A;  1FC7 A;  3TMH A;  2W4F A;  2EEI A;  3PDV A;  1OBY A;  1V5Q A;  2GEF A;  2KG2 A;  4MPA A;  1WHD A;  4NXQ A;  3SOE A;  2DLU A;  3GCO A;  2M10 A;  2M0T A;  1N6F A;  4Z8J A;  3PV2 A;  1N7E A;  1YBO A;  3TSW A;  1UM1 A;  3I1E A;  2EJY A;  1G9O A;  1I16 A;  2EGK A;  2M0U A;  3LNY A;  1WFG A;  1QAV B;  2OSG A;  1RY4 A;  2LA8 A;  4UU6 A;  2OGP A;  3R69 A;  1FC6 A;  5HF1 A;  1U38 A;  2REY A;  4JL7 A;  4OEO A;  2EEJ A;  2V90 A;  4REY A;  2KYL A;  5G1D A;  2D92 A;  1VJ6 A;  2KJK A;  1WIF A;  1MC7 A;  2KJP A;  3K1R A;  2RRM A;  2OS6 A;  3PV4 A;  2YT7 A;  3CBZ A;  2UZC A;  2Z9I A;  2OZF A;  2ZPL A;  3CBY A;  1RZX A;  2AWX A;  2PKU A;  3DIW A;  3QIK A;  4P2A B;  4NXP A;  1WI2 A;  4NMV A;  2I0I A;  2ENO A;  4JOE A;  1UEP A;  4YYX A;  1UM7 A;  3EGH C;  2F5Y A;  3DJA A;  3GJ9 A;  1I92 A;  2P3W A;  1OBX A;  3HPK A;  4OEP A;  2V1W A;  1N7F A;  5F67 A;  3I4W A;  2M3M A;  2L97 A;  2PKT A;  5HFB A;  3QJM A;  3O5N A;  4JOR A;  1WJL A;  3OTP A;  4HOP B;  1UEW A;  5HJ1 A;  3AXA A;  2M0Z A;  2LC6 A;  5HF4 A;  1WF8 A;  1WHA A;  2FCF A;  5D13 A;  2AWU A;  2YTW A;  1N7T A;  4K78 A;  2VPH A;  5HEY A;  3WKL A;  1SOZ A;  2EDV A;  2QBW A;  4NMP A;  2KV8 A;  1L6O A;  3QGL A;  3VQG A;  3K50 A;  1GM1 A;  3NFL A;  2DLS A;  2YUB A;  1V1T A;  2H2C A;  4GVC A;  4NMO A;  4L8N A;  1X9Z A;  2I6V A;  2KA9 A;  2DMZ A;  3I18 A;  2KJD A;  4O06 A;  5HFD A;  4NNM A;  2R3Y A;  3NFK A;  1GQ5 A;  2H3L A;  2OPG A;  3KZD A;  2AIN A;  1WG6 A;  2X7Z A;  2KRG A;  2JWE A;  4K76 A;  1M5Z A;  2K20 A;  4RI0 A;  1QLC A;  2K1Z A;  1VAE A;  2FN5 A;  2GZV A;  1KEF A;  3CYY A;  2DB5 A;  1W9Q A;  3NGH A;  2HE4 A;  3DOR A;  1FCF A;  1N6D A;  4JOH A;  4IC6 A;  4R2Z A;  1BFE A;  2I04 A;  2IWN A;  2EGN A;  3FY5 A;  5IL9 A;  1UIT A;  4JOF A;  3CH8 A;  3CBX A;  1UJU A;  1Q3P A;  1X8S A;  4FLN A;  1VCW A;  4Q2Q A;  3RLE A;  3SFJ A;  1TE0 A;  5E21 A;  5EZ0 A;  5B42 A;  2F0A A;  3GDV A;  3O46 A;  1BE9 A;  2KOJ A;  1QAV A;  2HE2 A;  2KOH A;  1V5L A;  2PA1 A;  1VB7 A;  3SHU A;  3SUZ A;  1OBZ A;  2KAW A;  1LCY A;  3K82 A;  3TSV A;  4NMR A;  2MX6 A;  1UFX A;  4OAJ A;  2PDZ A;  3RL7 A;  2QG1 A;  2EEH A;  2DC2 A;  2CSS A;  2VWR A;  3ID2 A;  3QE1 A;  3ZRT A;  4Q3H A;  2KPK A;  3GSL A;  1KY9 A;  4GVD A;  3VQF A;  5GLJ A;  3ID3 A;  3KHF A;  4E3B A;  1V6B A;  4E34 A;  2Z17 A;  2IWP A;  3ID4 A;  4GHN A;  4Q2N A;  3QO6 A;  1IHJ A;  2JIN A;  3PDZ A;  2E7K A;  4NNL A;  4G69 A;  2M0V A;  1WFV A;  2ZPM A;  2CSJ A;  4JOG A;  5E1Y A;  5EYZ A;  1UF1 A;  1NF3 C;  2LC7 A;  4LMM A;  4K6Y A;  3DJ3 A;  5F3X A;  3CS0 A;  1U37 A;  4Q2O A;  4HOP A;  5E11 A;  1IU0 A;  2KL1 A;  1TQ3 A;  2MHO A;  5E22 A;  5G1E A;  4YDP A;  2QKU A;  1UEQ A;  2IWO A;  3MH4 A;  3MH7 A;  1P1D A;  2AWW A;  2O2T A;  5HFF A;  2Q9V A;  1RGR A;  1T2M A;  1D5G A;  1IU2 A;  3HVQ C;  5JXB A;  3QJN A;  4JOP A;  4JOJ A;  4E35 A;  2EGO A;  3QDO A;  3LNX A;  2VSV A;  2OQS A;  2W7R A;  2KOM A;  1Y7N A;  2VRF A;  2EEG A;  2FE5 A;  2L4S A;  4JJ3 A;  4XHV A;  3TSZ A;  2FNE A;  3SHW A;  1N99 A;  2JIK A;  1SOT A;  5HED A;  5I7Z A;  4K75 A;  5A2P A;  2OCS A;  3HPM A;  2QKT A;  2BYG A;  2JOA A;  5HDY A;  3EGG C;  2D8I A;  5HFE A;  2WL7 A;  1X5R A;  3KDK A;  2JRE A;  2D90 A;  3GGE A;  2EAQ A;  4EDJ A;  1N6E A;  4Q6S A;  3E17 A;  5DTH A;  4Q6H A;  2VSP A;  3STJ A;  2PNT A;  5ILB A;  1Q3O A;  2L4T A;  2KQF A;  1QAU A;  2HGA A;  1Z87 A;  3GCN A;  1TP5 A;  1ZOK A;  4Z33 A;  1X5N A;  1K32 A;  2EXG A;  2EDP A;  2VZ5 A;  2LOB A;  2JSN A;  3BPU A;  3R68 A;  1X45 A;  1Y8T A;  2EDZ A;  4JJ0 A;  2H3M A;  4NMT A;  1U39 A;  3PV5 A;  3CC0 A;  1XZ9 A;  2LUI A;  1UJV A;  2DJT A;  2H2B A;  5HET A;  1PDR A;  1ZUB A;  4AMH A;  1VA8 A;  4N6X A;  2CS5 A;  2DAZ A;  3NCV A;  2JXO A;  5HEB A;  3R0H A;  1P1E A;  1OZI A;  3DJ1 A;  3GAB A;  2I0L A;  3ID1 A;  1X6D A;  1Z86 A;  4JOK A;  5FHT A;  1GQ4 A;  1WH1 A;  5FB8 C;  4WYT A;  2YUY A;  5B6L A;  2G5M B;  4P0C A;  1MFL A;  2I4S A;  4UU5 A;  1UEZ A;  4PQW A;  2QT5 A;  5HFC A;  4NXR A;  2PZD A;  3B76 A;  1FC9 A;  2I1N A;  2EV8 A;  2RCZ A;  3JXT A;  5GND A;  2DKR A;  3MH6 A;  5H3J A;  2IWQ A;  4NMS A;  1NTE A;  2Q3G A;  3PS4 A;  3RL8 A;  1WI4 A;  1TP3 A;  2OMJ A;  3L4F D;  4KFW A;  2EHR A;  2G2L A;  3KZE A;  4NMQ A;  1UJD A;  2KBS A;  1Q7X A;  1W9E A;  3KDG A;  1X5Q A;  1B8Q A;  4Q2P A;  1R6J A; 
#chains in the Genus database with same CATH homology
 2R4H A;  1MFG A;  4WYU A;  2JIL A;  2QKV A;  2DM8 A;  4K72 A;  5E6P B;  1V62 A;  1KWA A;  3GDU A;  4F8K A;  1U3B A;  3GDS A;  1W9O A;  4FGM A;  1WF7 A;  3OU0 A;  1UHP A;  4KFV A;  1RGW A;  3WKM A;  2KPL A;  4H11 A;  2YT8 A;  1FC7 A;  3TMH A;  2W4F A;  2EEI A;  3PDV A;  1OBY A;  1V5Q A;  2GEF A;  2KG2 A;  4MPA A;  1WHD A;  4NXQ A;  3SOE A;  2DLU A;  3GCO A;  2M10 A;  2M0T A;  1N6F A;  4Z8J A;  3PV2 A;  1N7E A;  1YBO A;  3TSW A;  1UM1 A;  3I1E A;  2EJY A;  1G9O A;  1I16 A;  2EGK A;  2M0U A;  3LNY A;  1WFG A;  1QAV B;  2OSG A;  1RY4 A;  2LA8 A;  4UU6 A;  2OGP A;  3R69 A;  1FC6 A;  5HF1 A;  1U38 A;  2REY A;  4JL7 A;  4OEO A;  2EEJ A;  2V90 A;  4REY A;  2KYL A;  5G1D A;  2D92 A;  1VJ6 A;  2KJK A;  1WIF A;  1MC7 A;  2KJP A;  3K1R A;  2RRM A;  2OS6 A;  3PV4 A;  2YT7 A;  3CBZ A;  2UZC A;  2Z9I A;  2OZF A;  2ZPL A;  3CBY A;  1RZX A;  2AWX A;  2PKU A;  3DIW A;  3QIK A;  4P2A B;  4NXP A;  1WI2 A;  4NMV A;  2I0I A;  2ENO A;  4JOE A;  1UEP A;  4YYX A;  1UM7 A;  3EGH C;  2F5Y A;  3DJA A;  3GJ9 A;  1I92 A;  2P3W A;  1OBX A;  3HPK A;  4OEP A;  2V1W A;  1N7F A;  5F67 A;  3I4W A;  2M3M A;  2L97 A;  2PKT A;  5HFB A;  3QJM A;  3O5N A;  4JOR A;  1WJL A;  3OTP A;  4HOP B;  1UEW A;  5HJ1 A;  3AXA A;  2M0Z A;  2LC6 A;  5HF4 A;  1WF8 A;  1WHA A;  2FCF A;  5D13 A;  2AWU A;  2YTW A;  1N7T A;  4K78 A;  2VPH A;  5HEY A;  3WKL A;  1SOZ A;  2EDV A;  2QBW A;  4NMP A;  2KV8 A;  1L6O A;  3QGL A;  3VQG A;  3K50 A;  1GM1 A;  3NFL A;  2DLS A;  2YUB A;  1V1T A;  2H2C A;  4GVC A;  4NMO A;  4L8N A;  1X9Z A;  2I6V A;  2KA9 A;  2DMZ A;  3I18 A;  2KJD A;  4O06 A;  5HFD A;  4NNM A;  2R3Y A;  3NFK A;  1GQ5 A;  2H3L A;  2OPG A;  3KZD A;  2AIN A;  1WG6 A;  2X7Z A;  2KRG A;  2JWE A;  4K76 A;  1M5Z A;  2K20 A;  4RI0 A;  1QLC A;  2K1Z A;  1VAE A;  2FN5 A;  2GZV A;  1KEF A;  3CYY A;  2DB5 A;  1W9Q A;  3NGH A;  2HE4 A;  3DOR A;  1FCF A;  1N6D A;  4JOH A;  4IC6 A;  4R2Z A;  1BFE A;  2I04 A;  2IWN A;  2EGN A;  3FY5 A;  5IL9 A;  1UIT A;  4JOF A;  3CH8 A;  3CBX A;  1UJU A;  1Q3P A;  1X8S A;  4FLN A;  1VCW A;  4Q2Q A;  3RLE A;  3SFJ A;  1TE0 A;  5E21 A;  5EZ0 A;  5B42 A;  2F0A A;  3GDV A;  3O46 A;  1BE9 A;  2KOJ A;  1QAV A;  2HE2 A;  2KOH A;  1V5L A;  2PA1 A;  1VB7 A;  3SHU A;  3SUZ A;  1OBZ A;  2KAW A;  1LCY A;  3K82 A;  3TSV A;  4NMR A;  2MX6 A;  1UFX A;  4OAJ A;  2PDZ A;  3RL7 A;  2QG1 A;  2EEH A;  2DC2 A;  2CSS A;  2VWR A;  3ID2 A;  3QE1 A;  3ZRT A;  4Q3H A;  2KPK A;  3GSL A;  1KY9 A;  4GVD A;  3VQF A;  5GLJ A;  3ID3 A;  3KHF A;  4E3B A;  1V6B A;  4E34 A;  2Z17 A;  2IWP A;  3ID4 A;  4GHN A;  4Q2N A;  3QO6 A;  1IHJ A;  2JIN A;  3PDZ A;  2E7K A;  4NNL A;  4G69 A;  2M0V A;  1WFV A;  2ZPM A;  2CSJ A;  4JOG A;  5E1Y A;  5EYZ A;  1UF1 A;  1NF3 C;  2LC7 A;  4LMM A;  4K6Y A;  3DJ3 A;  5F3X A;  3CS0 A;  1U37 A;  4Q2O A;  4HOP A;  5E11 A;  1IU0 A;  2KL1 A;  1TQ3 A;  2MHO A;  5E22 A;  5G1E A;  4YDP A;  2QKU A;  1UEQ A;  2IWO A;  3MH4 A;  3MH7 A;  1P1D A;  2AWW A;  2O2T A;  5HFF A;  2Q9V A;  1RGR A;  1T2M A;  1D5G A;  1IU2 A;  3HVQ C;  5JXB A;  3QJN A;  4JOP A;  4JOJ A;  4E35 A;  2EGO A;  3QDO A;  3LNX A;  2VSV A;  2OQS A;  2W7R A;  2KOM A;  1Y7N A;  2VRF A;  2EEG A;  2FE5 A;  2L4S A;  4JJ3 A;  4XHV A;  3TSZ A;  2FNE A;  3SHW A;  1N99 A;  2JIK A;  1SOT A;  5HED A;  5I7Z A;  4K75 A;  5A2P A;  2OCS A;  3HPM A;  2QKT A;  2BYG A;  2JOA A;  5HDY A;  3EGG C;  2D8I A;  5HFE A;  2WL7 A;  1X5R A;  3KDK A;  2JRE A;  2D90 A;  3GGE A;  2EAQ A;  4EDJ A;  1N6E A;  4Q6S A;  3E17 A;  5DTH A;  4Q6H A;  2VSP A;  3STJ A;  2PNT A;  5ILB A;  1Q3O A;  2L4T A;  2KQF A;  1QAU A;  2HGA A;  1Z87 A;  3GCN A;  1TP5 A;  1ZOK A;  4Z33 A;  1X5N A;  1K32 A;  2EXG A;  2EDP A;  2VZ5 A;  2LOB A;  2JSN A;  3BPU A;  3R68 A;  1X45 A;  1Y8T A;  2EDZ A;  4JJ0 A;  2H3M A;  4NMT A;  1U39 A;  3PV5 A;  3CC0 A;  1XZ9 A;  2LUI A;  1UJV A;  2DJT A;  2H2B A;  5HET A;  1PDR A;  1ZUB A;  4AMH A;  1VA8 A;  4N6X A;  2CS5 A;  2DAZ A;  3NCV A;  2JXO A;  5HEB A;  3R0H A;  1P1E A;  1OZI A;  3DJ1 A;  3GAB A;  2I0L A;  3ID1 A;  1X6D A;  1Z86 A;  4JOK A;  5FHT A;  1GQ4 A;  1WH1 A;  5FB8 C;  4WYT A;  2YUY A;  5B6L A;  2G5M B;  4P0C A;  1MFL A;  2I4S A;  4UU5 A;  1UEZ A;  4PQW A;  2QT5 A;  5HFC A;  4NXR A;  2PZD A;  3B76 A;  1FC9 A;  2I1N A;  2EV8 A;  2RCZ A;  3JXT A;  5GND A;  2DKR A;  3MH6 A;  5H3J A;  2IWQ A;  4NMS A;  1NTE A;  2Q3G A;  3PS4 A;  3RL8 A;  1WI4 A;  1TP3 A;  2OMJ A;  3L4F D;  4KFW A;  2EHR A;  2G2L A;  3KZE A;  4NMQ A;  1UJD A;  2KBS A;  1Q7X A;  1W9E A;  3KDG A;  1X5Q A;  1B8Q A;  4Q2P A;  1R6J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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