1CN2A

Solution structure of toxin 2 from centruroides noxius hoffmann, a beta scorpion neurotoxin acting on sodium channels, nmr, 15 structures
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
pubmed doi rcsb
molecule tags Neurotoxin
molecule keywords TOXIN 2
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 1998-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1cn2A00
1I6GA 1BRZA 1LQIA 2M8BB 1ZVGA 1B3CA 2LJMA 1TI5A 1I2UA 2LR3A 5CY0A 1WWNA 4HHFA 2BRZA 2NY8X 1NRBA 1WT7A 2N2QA 1T7BA 1AYJA 1MR4A 1DQ7A 4CQKA 1LQQA 1BMRA 1C55A 2LT8A 1B7DA 1ZU3A 1VNBA 2KBKA 1MYNA 2KSKA 4HE7A 4V1DC 4AEIA 1T0ZA 1OMYA 2ASCA 1GPSA 1T7AA 2LKBA 2YEOA 1L4VA 2ATBA 1ZUTA 2B3CA 2I61A 1JZAA 2KBJA 1VNAA 1T7EA 2NY9X 2E3FA 1AHOA 1ZYWA 1NRAA 1JZBA 2B68A 2LY6A 4AAZA 1OZZA 1WMTA 4UJ0A 1DJTA 1I6FA 2MZ0A 2N69A 3E7UX 2LJ7A 1JXCA 1ZFUA 2KBHA 1P00A 2KJAA 1SN4A 2YC1C 2E0HA 1SNBA 1SEGA 3E7RL 2KPYA 2KGQA 1ZYVA 2SN3A 1KV0A 3PSMA 1N4NA 1PE4A 2N2RA 1ZVEA 1I2VA 1NE5A 1SN1A 1P0AA 4AB0A 2N66A 1CHZA 1T1TA 1GPTA 2A7TA 2GL1A 2E3GA 1CN2A 1ICAA 1PX9A 1C56A 4KYPA 1PTXA 1JKZA 5KK4A 1FH3A 1NH5A 2KYQA 2LY5A 2YBRC 2LI7A 1NPIA 1BK8A 1BCGA 1LQHA
chains in the Genus database with same CATH superfamily
3ATUA 3L56A 1I6GA 2G2KA 4H5TA 4HWIA 3KP1A 3LDNA 1BRZA 1LQIA 2M8BB 1ZVGA 2K35A 5FPDA 1B3CA 2LJMA 1TI5A 1I2UA 2LR3A 3QMLA 4H5NA 1NGBA 5BPMA 5CY0A 1WWNA 3FZKA 3KOYA 4HHFA 2BRZA 2NY8X 1NGIA 1NRBA 1QQOA 4UADE 5AR0A 1NGJA 1WT7A 1KAYA 2N2QA 1T7BA 2QWMA 2D56A 5F0XA 1AYJA 3FE1A 5AQKA 4H5WA 1MR4A 5F2RA 5AQRA 5AQJA 3SF4D 2LN8A 5BN9A 3QFPA 5AQWA 1NGAA 1DQ7A 2KHOA 4CQKA 1LQQA 2VY6A 1BMRA 2E8AA 5BPLA 1KAXA 1C55A 2LT8A 1B7DA 3GDQA 3KOWA 1ZU3A 2E2FA 5BPNA 1VNBA 2KBKA 4H5VA 1MYNA 5AQMA 5AQVA 5AQGA 3R2VA 4FL9A 1BCGA 2KSKA 2QWNA 2QWRA 4HE7A 4IO8A 1BA1A 4V1DC 5AQXA 4AEIA 1T0ZA 1POIA 3FZHA 1OMYA 2ASCA 3HSCA 4H5RA 1GPSA 3LDLA 1T7AA 2LKBA 2YEOA 1L4VA 2ATBA 4KBOA 5EXWA 1ZUTA 2B3CA 2I61A 5EY4A 1JZAA 2KBJA 3C7NA 1XRSB 1NGGA 3FZMA 1DKGD 2MBKA 3CQXA 3GKUA 1VNAA 1T7EA 2NY9X 2E3FA 3KOXA 1AHOA 1ZYWA 1NRAA 5AQFA 5AQHA 1K8BA 3D2FA 3KOZA 1JZBA 3QFUA 3QI7A 2B68A 5AQIA 5FPNA 2LY6A 1ATRA 4AAZA 1OZZA 2QWQA 4FSVA 1WMTA 3IUCA 5AQNA 5AQUA 2BUPA 3LDOA 1HPMA 5AQLA 5AQSA 4UJ0A 5AQPA 3BK3C 1DJTA 2YIPA 1I6FA 2MZ0A 2N69A 3E7UX 2LJ7A 3KVGA 1JXCA 1NGFA 1KAZA 1ZFUA 1P00A 2KBHA 2QW9A 3GL1A 1BA0A 3ATVA 1BUPA 1SN4A 2KJAA 1NGCA 2E0HA 2YC1C 1SNBA 1HJOA 1NGHA 4GNIA 3D2EB 1HX1A 1SEGA 3M3ZA 3E7RL 3FZLA 5FPMA 2KPYA 3L4IA 2KGQA 1ZYVA 2SN3A 2V7ZA 1UGLA 5AQQA 1KV0A 3FZFA 1YUWA 3PSMA 1N4NA 2QWPA 5FPEA 1PE4A 2N2RA 1ZVEA 1I2VA 1NE5A 2E88A 1SN1A 5BN8A 1NGDA 2QXLA 1P0AA 2YILA 1QQNA 2N66A 3KHWA 4AB0A 1CHZA 4UAEF 1T1TA 2QWLA 3I33A 3L6QA 1GPTA 5EVZA 4UAFE 2A7TA 2GL1A 2QWOA 3KC6A 2YIOA 3A8YA 3AY9A 5AQYA 3LDQA 3C7NB 2E3GA 1CN2A 1ICAA 5EX5A 1PX9A 5AQTA 1C56A 1QQMA 4KYPA 5AQOA 1PTXA 5AQZA 3JXUA 1JKZA 5KK4A 1FH3A 1S3XA 3CW4A 2GMOA 2JDQD 1NH5A 2KYQA 3D2FB 3KP0A 2LY5A 2YBRC 3LDPA 2LI7A 3D2EA 1NPIA 5F1XA 1BK8A 1NGEA 2MN5A 1LQHA 1ATSA
chains in the Genus database with same CATH topology
1I6GA 1BRZA 1LQIA 2M8BB 1ZVGA 1B3CA 2LJMA 1TI5A 1I2UA 2LR3A 5CY0A 1WWNA 4HHFA 2BRZA 2NY8X 1NRBA 1WT7A 2N2QA 1T7BA 1AYJA 1MR4A 1DQ7A 4CQKA 1LQQA 1BMRA 1C55A 2LT8A 1B7DA 1ZU3A 1VNBA 2KBKA 1MYNA 2KSKA 4HE7A 4V1DC 4AEIA 1T0ZA 1OMYA 2ASCA 1GPSA 1T7AA 2LKBA 2YEOA 1L4VA 2ATBA 1ZUTA 2B3CA 2I61A 1JZAA 2KBJA 1VNAA 1T7EA 2NY9X 2E3FA 1AHOA 1ZYWA 1NRAA 1JZBA 2B68A 2LY6A 4AAZA 1OZZA 1WMTA 4UJ0A 1DJTA 1I6FA 2MZ0A 2N69A 3E7UX 2LJ7A 1JXCA 1ZFUA 2KBHA 1P00A 2KJAA 1SN4A 2YC1C 2E0HA 1SNBA 1SEGA 3E7RL 2KPYA 2KGQA 1ZYVA 2SN3A 1KV0A 3PSMA 1N4NA 1PE4A 2N2RA 1ZVEA 1I2VA 1NE5A 1SN1A 1P0AA 4AB0A 2N66A 1CHZA 1T1TA 1GPTA 2A7TA 2GL1A 2E3GA 1CN2A 1ICAA 1PX9A 1C56A 4KYPA 1PTXA 1JKZA 5KK4A 1FH3A 1NH5A 2KYQA 2LY5A 2YBRC 2LI7A 1NPIA 1BK8A 1BCGA 1LQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6G A;  1BRZ A;  1LQI A;  2M8B B;  1ZVG A;  1B3C A;  2LJM A;  1TI5 A;  1I2U A;  2LR3 A;  5CY0 A;  1WWN A;  4HHF A;  2BRZ A;  2NY8 X;  1NRB A;  1WT7 A;  2N2Q A;  1T7B A;  1AYJ A;  1MR4 A;  1DQ7 A;  4CQK A;  1LQQ A;  1BMR A;  1C55 A;  2LT8 A;  1B7D A;  1ZU3 A;  1VNB A;  2KBK A;  1MYN A;  2KSK A;  4HE7 A;  4V1D C;  4AEI A;  1T0Z A;  1OMY A;  2ASC A;  1GPS A;  1T7A A;  2LKB A;  2YEO A;  1L4V A;  2ATB A;  1ZUT A;  2B3C A;  2I61 A;  1JZA A;  2KBJ A;  1VNA A;  1T7E A;  2NY9 X;  2E3F A;  1AHO A;  1ZYW A;  1NRA A;  1JZB A;  2B68 A;  2LY6 A;  4AAZ A;  1OZZ A;  1WMT A;  4UJ0 A;  1DJT A;  1I6F A;  2MZ0 A;  2N69 A;  3E7U X;  2LJ7 A;  1JXC A;  1ZFU A;  2KBH A;  1P00 A;  2KJA A;  1SN4 A;  2YC1 C;  2E0H A;  1SNB A;  1SEG A;  3E7R L;  2KPY A;  2KGQ A;  1ZYV A;  2SN3 A;  1KV0 A;  3PSM A;  1N4N A;  1PE4 A;  2N2R A;  1ZVE A;  1I2V A;  1NE5 A;  1SN1 A;  1P0A A;  4AB0 A;  2N66 A;  1CHZ A;  1T1T A;  1GPT A;  2A7T A;  2GL1 A;  2E3G A;  1CN2 A;  1ICA A;  1PX9 A;  1C56 A;  4KYP A;  1PTX A;  1JKZ A;  5KK4 A;  1FH3 A;  1NH5 A;  2KYQ A;  2LY5 A;  2YBR C;  2LI7 A;  1NPI A;  1BK8 A;  1BCG A;  1LQH A; 
#chains in the Genus database with same CATH topology
 3ATU A;  3L56 A;  1I6G A;  2G2K A;  4H5T A;  4HWI A;  3KP1 A;  3LDN A;  1BRZ A;  1LQI A;  2M8B B;  1ZVG A;  2K35 A;  5FPD A;  1B3C A;  2LJM A;  1TI5 A;  1I2U A;  2LR3 A;  3QML A;  4H5N A;  1NGB A;  5BPM A;  5CY0 A;  1WWN A;  3FZK A;  3KOY A;  4HHF A;  2BRZ A;  2NY8 X;  1NGI A;  1NRB A;  1QQO A;  4UAD E;  5AR0 A;  1NGJ A;  1WT7 A;  1KAY A;  2N2Q A;  1T7B A;  2QWM A;  2D56 A;  5F0X A;  1AYJ A;  3FE1 A;  5AQK A;  4H5W A;  1MR4 A;  5F2R A;  5AQR A;  5AQJ A;  3SF4 D;  2LN8 A;  5BN9 A;  3QFP A;  5AQW A;  1NGA A;  1DQ7 A;  2KHO A;  4CQK A;  1LQQ A;  2VY6 A;  1BMR A;  2E8A A;  5BPL A;  1KAX A;  1C55 A;  2LT8 A;  1B7D A;  3GDQ A;  3KOW A;  1ZU3 A;  2E2F A;  5BPN A;  1VNB A;  2KBK A;  4H5V A;  1MYN A;  5AQM A;  5AQV A;  5AQG A;  3R2V A;  4FL9 A;  1BCG A;  2KSK A;  2QWN A;  2QWR A;  4HE7 A;  4IO8 A;  1BA1 A;  4V1D C;  5AQX A;  4AEI A;  1T0Z A;  1POI A;  3FZH A;  1OMY A;  2ASC A;  3HSC A;  4H5R A;  1GPS A;  3LDL A;  1T7A A;  2LKB A;  2YEO A;  1L4V A;  2ATB A;  4KBO A;  5EXW A;  1ZUT A;  2B3C A;  2I61 A;  5EY4 A;  1JZA A;  2KBJ A;  3C7N A;  1XRS B;  1NGG A;  3FZM A;  1DKG D;  2MBK A;  3CQX A;  3GKU A;  1VNA A;  1T7E A;  2NY9 X;  2E3F A;  3KOX A;  1AHO A;  1ZYW A;  1NRA A;  5AQF A;  5AQH A;  1K8B A;  3D2F A;  3KOZ A;  1JZB A;  3QFU A;  3QI7 A;  2B68 A;  5AQI A;  5FPN A;  2LY6 A;  1ATR A;  4AAZ A;  1OZZ A;  2QWQ A;  4FSV A;  1WMT A;  3IUC A;  5AQN A;  5AQU A;  2BUP A;  3LDO A;  1HPM A;  5AQL A;  5AQS A;  4UJ0 A;  5AQP A;  3BK3 C;  1DJT A;  2YIP A;  1I6F A;  2MZ0 A;  2N69 A;  3E7U X;  2LJ7 A;  3KVG A;  1JXC A;  1NGF A;  1KAZ A;  1ZFU A;  1P00 A;  2KBH A;  2QW9 A;  3GL1 A;  1BA0 A;  3ATV A;  1BUP A;  1SN4 A;  2KJA A;  1NGC A;  2E0H A;  2YC1 C;  1SNB A;  1HJO A;  1NGH A;  4GNI A;  3D2E B;  1HX1 A;  1SEG A;  3M3Z A;  3E7R L;  3FZL A;  5FPM A;  2KPY A;  3L4I A;  2KGQ A;  1ZYV A;  2SN3 A;  2V7Z A;  1UGL A;  5AQQ A;  1KV0 A;  3FZF A;  1YUW A;  3PSM A;  1N4N A;  2QWP A;  5FPE A;  1PE4 A;  2N2R A;  1ZVE A;  1I2V A;  1NE5 A;  2E88 A;  1SN1 A;  5BN8 A;  1NGD A;  2QXL A;  1P0A A;  2YIL A;  1QQN A;  2N66 A;  3KHW A;  4AB0 A;  1CHZ A;  4UAE F;  1T1T A;  2QWL A;  3I33 A;  3L6Q A;  1GPT A;  5EVZ A;  4UAF E;  2A7T A;  2GL1 A;  2QWO A;  3KC6 A;  2YIO A;  3A8Y A;  3AY9 A;  5AQY A;  3LDQ A;  3C7N B;  2E3G A;  1CN2 A;  1ICA A;  5EX5 A;  1PX9 A;  5AQT A;  1C56 A;  1QQM A;  4KYP A;  5AQO A;  1PTX A;  5AQZ A;  3JXU A;  1JKZ A;  5KK4 A;  1FH3 A;  1S3X A;  3CW4 A;  2GMO A;  2JDQ D;  1NH5 A;  2KYQ A;  3D2F B;  3KP0 A;  2LY5 A;  2YBR C;  3LDP A;  2LI7 A;  3D2E A;  1NPI A;  5F1X A;  1BK8 A;  1NGE A;  2MN5 A;  1LQH A;  1ATS A; 
#chains in the Genus database with same CATH homology
 1I6G A;  1BRZ A;  1LQI A;  2M8B B;  1ZVG A;  1B3C A;  2LJM A;  1TI5 A;  1I2U A;  2LR3 A;  5CY0 A;  1WWN A;  4HHF A;  2BRZ A;  2NY8 X;  1NRB A;  1WT7 A;  2N2Q A;  1T7B A;  1AYJ A;  1MR4 A;  1DQ7 A;  4CQK A;  1LQQ A;  1BMR A;  1C55 A;  2LT8 A;  1B7D A;  1ZU3 A;  1VNB A;  2KBK A;  1MYN A;  2KSK A;  4HE7 A;  4V1D C;  4AEI A;  1T0Z A;  1OMY A;  2ASC A;  1GPS A;  1T7A A;  2LKB A;  2YEO A;  1L4V A;  2ATB A;  1ZUT A;  2B3C A;  2I61 A;  1JZA A;  2KBJ A;  1VNA A;  1T7E A;  2NY9 X;  2E3F A;  1AHO A;  1ZYW A;  1NRA A;  1JZB A;  2B68 A;  2LY6 A;  4AAZ A;  1OZZ A;  1WMT A;  4UJ0 A;  1DJT A;  1I6F A;  2MZ0 A;  2N69 A;  3E7U X;  2LJ7 A;  1JXC A;  1ZFU A;  2KBH A;  1P00 A;  2KJA A;  1SN4 A;  2YC1 C;  2E0H A;  1SNB A;  1SEG A;  3E7R L;  2KPY A;  2KGQ A;  1ZYV A;  2SN3 A;  1KV0 A;  3PSM A;  1N4N A;  1PE4 A;  2N2R A;  1ZVE A;  1I2V A;  1NE5 A;  1SN1 A;  1P0A A;  4AB0 A;  2N66 A;  1CHZ A;  1T1T A;  1GPT A;  2A7T A;  2GL1 A;  2E3G A;  1CN2 A;  1ICA A;  1PX9 A;  1C56 A;  4KYP A;  1PTX A;  1JKZ A;  5KK4 A;  1FH3 A;  1NH5 A;  2KYQ A;  2LY5 A;  2YBR C;  2LI7 A;  1NPI A;  1BK8 A;  1BCG A;  1LQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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