1CN2A

Solution structure of toxin 2 from centruroides noxius hoffmann, a beta scorpion neurotoxin acting on sodium channels, nmr, 15 structures
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
pubmed doi rcsb
molecule tags Neurotoxin
molecule keywords TOXIN 2
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 1998-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1cn2A00
2N66A 1WT7A 2KYQA 1JKZA 4AEIA 1OMYA 2KPYA 2LY6A 1WWNA 1JXCA 2E3FA 1LQQA 2B3CA 1NPIA 2LI7A 4AAZA 1DJTA 1LQIA 2KJAA 1I2VA 2ATBA 1N4NA 1ZUTA 1AHOA 1KV0A 2E0HA 2MZ0A 2ASCA 1VNAA 1ZYWA 1PE4A 1T7AA 2N2RA 2YEOA 2M8BB 4UJ0A 3E7UX 1NE5A 1WMTA 2KSKA 1T7EA 3PSMA 1LQHA 2LJMA 4HHFA 2YC1C 1B7DA 1NRAA 1SNBA 1PX9A 4CQKA 1L4VA 4AB0A 1T7BA 2YBRC 1BRZA 1C56A 1C55A 1ZFUA 2B68A 1B3CA 2LKBA 1P0AA 2N2QA 4V1DC 1ICAA 1NH5A 1VNBA 2KBKA 2E3GA 2NY9X 1SN1A 2LJ7A 4HE7A 2I61A 2BRZA 1GPTA 1T1TA 1SEGA 1DQ7A 1OZZA 1PTXA 1BCGA 1ZVGA 1I6GA 1T0ZA 2KGQA 3E7RL 5CY0A 1TI5A 4KYPA 2A7TA 1JZAA 1NRBA 1BMRA 2KBJA 5KK4A 1SN4A 1JZBA 1BK8A 1GPSA 1I6FA 1MR4A 2LY5A 1I2UA 2N69A 2KBHA 1CN2A 1AYJA 1CHZA 1ZYVA 1ZVEA 2LR3A 2SN3A 1FH3A 1MYNA 1ZU3A 1P00A 2LT8A 2GL1A 2NY8X
chains in the Genus database with same CATH superfamily
2N66A 2JDQD 2BUPA 2QWRA 4FSVA 3FE1A 5AQXA 1WT7A 5AQGA 2KYQA 4H5TA 1JKZA 5AQTA 1NGGA 5FPNA 5EX5A 4AEIA 3KHWA 1OMYA 3LDQA 2KPYA 2LY6A 5AQLA 1ATRA 1WWNA 1JXCA 2E3FA 1LQQA 3LDPA 5AQOA 5AQSA 4UAEF 5F0XA 2B3CA 2LN8A 3LDOA 4UAFE 1NGAA 2E8AA 1NPIA 2LI7A 3D2FB 5BPLA 5BN8A 3A8YA 4AAZA 4GNIA 1DJTA 4H5NA 1LQIA 2KJAA 1I2VA 1HPMA 2ATBA 1N4NA 1ZUTA 3SF4D 1QQNA 3KP0A 3QFUA 1AHOA 1KV0A 1XRSB 2E0HA 2MZ0A 3C7NB 2ASCA 3KVGA 3R2VA 1VNAA 1ATSA 1PE4A 1BA0A 1ZYWA 3HSCA 3LDNA 1T7AA 2N2RA 2YEOA 2E2FA 2M8BB 5AQMA 4UJ0A 3E7UX 1NE5A 1WMTA 5AQYA 2KHOA 2KSKA 1T7EA 3PSMA 1LQHA 2QWQA 5FPDA 5EY4A 3KOWA 2LJMA 3AY9A 4HHFA 1NGCA 1B7DA 2YC1C 5AQFA 5F2RA 1BA1A 1K8BA 4UADE 1BUPA 5AQHA 1NRAA 1DKGD 5AQJA 5AQPA 3LDLA 1SNBA 1PX9A 4CQKA 1KAYA 2D56A 3QFPA 4H5RA 5EXWA 1L4VA 4AB0A 3KOXA 1T7BA 2YBRC 3L56A 3L4IA 3D2EB 3D2FA 1QQMA 1BRZA 1C56A 1NGDA 3IUCA 4IO8A 1C55A 1ZFUA 2B68A 1B3CA 2LKBA 1P0AA 5F1XA 2N2QA 5BPNA 1NGIA 5FPEA 4V1DC 4H5VA 2VY6A 1HJOA 3C7NA 1KAXA 4H5WA 3ATUA 3JXUA 1ICAA 3QI7A 1NH5A 2G2KA 1VNBA 3GKUA 2KBKA 2E3GA 2NY9X 1SN1A 2LJ7A 5AQZA 4HE7A 3ATVA 2I61A 5EVZA 3CW4A 3FZFA 5AQKA 2BRZA 5BN9A 2YILA 1GPTA 3CQXA 1T1TA 3FZLA 4FL9A 1HX1A 1SEGA 1DQ7A 1OZZA 1KAZA 1BCGA 1PTXA 1ZVGA 2QWNA 2QWMA 1I6GA 2QWPA 1NGFA 1NGJA 5AQWA 1T0ZA 1QQOA 2KGQA 3QMLA 3E7RL 4KBOA 1NGBA 5CY0A 5AQIA 5BPMA 1TI5A 3D2EA 3I33A 3FZHA 4KYPA 2A7TA 1JZAA 1NRBA 1BMRA 2KBJA 5KK4A 2GMOA 1SN4A 1JZBA 2QW9A 1UGLA 3L6QA 5AQVA 3M3ZA 5AQUA 3FZMA 5AQRA 1BK8A 5AR0A 2MBKA 2YIOA 3KC6A 1GPSA 1S3XA 1I6FA 1MR4A 2LY5A 3GDQA 2K35A 1I2UA 2N69A 2KBHA 2QWOA 2QWLA 4HWIA 5AQQA 1CN2A 3KOYA 1AYJA 1CHZA 2MN5A 3FZKA 2YIPA 1ZYVA 1NGHA 1ZVEA 2E88A 3BK3C 5FPMA 2V7ZA 3KOZA 3GL1A 1YUWA 1POIA 2LR3A 2SN3A 3KP1A 1FH3A 1MYNA 2LT8A 5AQNA 1ZU3A 1P00A 1NGEA 2GL1A 2NY8X 2QXLA
chains in the Genus database with same CATH topology
2N66A 1WT7A 2KYQA 1JKZA 4AEIA 1OMYA 2KPYA 2LY6A 1WWNA 1JXCA 2E3FA 1LQQA 2B3CA 1NPIA 2LI7A 4AAZA 1DJTA 1LQIA 2KJAA 1I2VA 2ATBA 1N4NA 1ZUTA 1AHOA 1KV0A 2E0HA 2MZ0A 2ASCA 1VNAA 1ZYWA 1PE4A 1T7AA 2N2RA 2YEOA 2M8BB 4UJ0A 3E7UX 1NE5A 1WMTA 2KSKA 1T7EA 3PSMA 1LQHA 2LJMA 4HHFA 2YC1C 1B7DA 1NRAA 1SNBA 1PX9A 4CQKA 1L4VA 4AB0A 1T7BA 2YBRC 1BRZA 1C56A 1C55A 1ZFUA 2B68A 1B3CA 2LKBA 1P0AA 2N2QA 4V1DC 1ICAA 1NH5A 1VNBA 2KBKA 2E3GA 2NY9X 1SN1A 2LJ7A 4HE7A 2I61A 2BRZA 1GPTA 1T1TA 1SEGA 1DQ7A 1OZZA 1PTXA 1BCGA 1ZVGA 1I6GA 1T0ZA 2KGQA 3E7RL 5CY0A 1TI5A 4KYPA 2A7TA 1JZAA 1NRBA 1BMRA 2KBJA 5KK4A 1SN4A 1JZBA 1BK8A 1GPSA 1I6FA 1MR4A 2LY5A 1I2UA 2N69A 2KBHA 1CN2A 1AYJA 1CHZA 1ZYVA 1ZVEA 2LR3A 2SN3A 1FH3A 1MYNA 1ZU3A 1P00A 2LT8A 2GL1A 2NY8X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N66 A;  1WT7 A;  2KYQ A;  1JKZ A;  4AEI A;  1OMY A;  2KPY A;  2LY6 A;  1WWN A;  1JXC A;  2E3F A;  1LQQ A;  2B3C A;  1NPI A;  2LI7 A;  4AAZ A;  1DJT A;  1LQI A;  2KJA A;  1I2V A;  2ATB A;  1N4N A;  1ZUT A;  1AHO A;  1KV0 A;  2E0H A;  2MZ0 A;  2ASC A;  1VNA A;  1ZYW A;  1PE4 A;  1T7A A;  2N2R A;  2YEO A;  2M8B B;  4UJ0 A;  3E7U X;  1NE5 A;  1WMT A;  2KSK A;  1T7E A;  3PSM A;  1LQH A;  2LJM A;  4HHF A;  2YC1 C;  1B7D A;  1NRA A;  1SNB A;  1PX9 A;  4CQK A;  1L4V A;  4AB0 A;  1T7B A;  2YBR C;  1BRZ A;  1C56 A;  1C55 A;  1ZFU A;  2B68 A;  1B3C A;  2LKB A;  1P0A A;  2N2Q A;  4V1D C;  1ICA A;  1NH5 A;  1VNB A;  2KBK A;  2E3G A;  2NY9 X;  1SN1 A;  2LJ7 A;  4HE7 A;  2I61 A;  2BRZ A;  1GPT A;  1T1T A;  1SEG A;  1DQ7 A;  1OZZ A;  1PTX A;  1BCG A;  1ZVG A;  1I6G A;  1T0Z A;  2KGQ A;  3E7R L;  5CY0 A;  1TI5 A;  4KYP A;  2A7T A;  1JZA A;  1NRB A;  1BMR A;  2KBJ A;  5KK4 A;  1SN4 A;  1JZB A;  1BK8 A;  1GPS A;  1I6F A;  1MR4 A;  2LY5 A;  1I2U A;  2N69 A;  2KBH A;  1CN2 A;  1AYJ A;  1CHZ A;  1ZYV A;  1ZVE A;  2LR3 A;  2SN3 A;  1FH3 A;  1MYN A;  1ZU3 A;  1P00 A;  2LT8 A;  2GL1 A;  2NY8 X; 
#chains in the Genus database with same CATH topology
 2N66 A;  2JDQ D;  2BUP A;  2QWR A;  4FSV A;  3FE1 A;  5AQX A;  1WT7 A;  5AQG A;  2KYQ A;  4H5T A;  1JKZ A;  5AQT A;  1NGG A;  5FPN A;  5EX5 A;  4AEI A;  3KHW A;  1OMY A;  3LDQ A;  2KPY A;  2LY6 A;  5AQL A;  1ATR A;  1WWN A;  1JXC A;  2E3F A;  1LQQ A;  3LDP A;  5AQO A;  5AQS A;  4UAE F;  5F0X A;  2B3C A;  2LN8 A;  3LDO A;  4UAF E;  1NGA A;  2E8A A;  1NPI A;  2LI7 A;  3D2F B;  5BPL A;  5BN8 A;  3A8Y A;  4AAZ A;  4GNI A;  1DJT A;  4H5N A;  1LQI A;  2KJA A;  1I2V A;  1HPM A;  2ATB A;  1N4N A;  1ZUT A;  3SF4 D;  1QQN A;  3KP0 A;  3QFU A;  1AHO A;  1KV0 A;  1XRS B;  2E0H A;  2MZ0 A;  3C7N B;  2ASC A;  3KVG A;  3R2V A;  1VNA A;  1ATS A;  1PE4 A;  1BA0 A;  1ZYW A;  3HSC A;  3LDN A;  1T7A A;  2N2R A;  2YEO A;  2E2F A;  2M8B B;  5AQM A;  4UJ0 A;  3E7U X;  1NE5 A;  1WMT A;  5AQY A;  2KHO A;  2KSK A;  1T7E A;  3PSM A;  1LQH A;  2QWQ A;  5FPD A;  5EY4 A;  3KOW A;  2LJM A;  3AY9 A;  4HHF A;  1NGC A;  1B7D A;  2YC1 C;  5AQF A;  5F2R A;  1BA1 A;  1K8B A;  4UAD E;  1BUP A;  5AQH A;  1NRA A;  1DKG D;  5AQJ A;  5AQP A;  3LDL A;  1SNB A;  1PX9 A;  4CQK A;  1KAY A;  2D56 A;  3QFP A;  4H5R A;  5EXW A;  1L4V A;  4AB0 A;  3KOX A;  1T7B A;  2YBR C;  3L56 A;  3L4I A;  3D2E B;  3D2F A;  1QQM A;  1BRZ A;  1C56 A;  1NGD A;  3IUC A;  4IO8 A;  1C55 A;  1ZFU A;  2B68 A;  1B3C A;  2LKB A;  1P0A A;  5F1X A;  2N2Q A;  5BPN A;  1NGI A;  5FPE A;  4V1D C;  4H5V A;  2VY6 A;  1HJO A;  3C7N A;  1KAX A;  4H5W A;  3ATU A;  3JXU A;  1ICA A;  3QI7 A;  1NH5 A;  2G2K A;  1VNB A;  3GKU A;  2KBK A;  2E3G A;  2NY9 X;  1SN1 A;  2LJ7 A;  5AQZ A;  4HE7 A;  3ATV A;  2I61 A;  5EVZ A;  3CW4 A;  3FZF A;  5AQK A;  2BRZ A;  5BN9 A;  2YIL A;  1GPT A;  3CQX A;  1T1T A;  3FZL A;  4FL9 A;  1HX1 A;  1SEG A;  1DQ7 A;  1OZZ A;  1KAZ A;  1BCG A;  1PTX A;  1ZVG A;  2QWN A;  2QWM A;  1I6G A;  2QWP A;  1NGF A;  1NGJ A;  5AQW A;  1T0Z A;  1QQO A;  2KGQ A;  3QML A;  3E7R L;  4KBO A;  1NGB A;  5CY0 A;  5AQI A;  5BPM A;  1TI5 A;  3D2E A;  3I33 A;  3FZH A;  4KYP A;  2A7T A;  1JZA A;  1NRB A;  1BMR A;  2KBJ A;  5KK4 A;  2GMO A;  1SN4 A;  1JZB A;  2QW9 A;  1UGL A;  3L6Q A;  5AQV A;  3M3Z A;  5AQU A;  3FZM A;  5AQR A;  1BK8 A;  5AR0 A;  2MBK A;  2YIO A;  3KC6 A;  1GPS A;  1S3X A;  1I6F A;  1MR4 A;  2LY5 A;  3GDQ A;  2K35 A;  1I2U A;  2N69 A;  2KBH A;  2QWO A;  2QWL A;  4HWI A;  5AQQ A;  1CN2 A;  3KOY A;  1AYJ A;  1CHZ A;  2MN5 A;  3FZK A;  2YIP A;  1ZYV A;  1NGH A;  1ZVE A;  2E88 A;  3BK3 C;  5FPM A;  2V7Z A;  3KOZ A;  3GL1 A;  1YUW A;  1POI A;  2LR3 A;  2SN3 A;  3KP1 A;  1FH3 A;  1MYN A;  2LT8 A;  5AQN A;  1ZU3 A;  1P00 A;  1NGE A;  2GL1 A;  2NY8 X;  2QXL A; 
#chains in the Genus database with same CATH homology
 2N66 A;  1WT7 A;  2KYQ A;  1JKZ A;  4AEI A;  1OMY A;  2KPY A;  2LY6 A;  1WWN A;  1JXC A;  2E3F A;  1LQQ A;  2B3C A;  1NPI A;  2LI7 A;  4AAZ A;  1DJT A;  1LQI A;  2KJA A;  1I2V A;  2ATB A;  1N4N A;  1ZUT A;  1AHO A;  1KV0 A;  2E0H A;  2MZ0 A;  2ASC A;  1VNA A;  1ZYW A;  1PE4 A;  1T7A A;  2N2R A;  2YEO A;  2M8B B;  4UJ0 A;  3E7U X;  1NE5 A;  1WMT A;  2KSK A;  1T7E A;  3PSM A;  1LQH A;  2LJM A;  4HHF A;  2YC1 C;  1B7D A;  1NRA A;  1SNB A;  1PX9 A;  4CQK A;  1L4V A;  4AB0 A;  1T7B A;  2YBR C;  1BRZ A;  1C56 A;  1C55 A;  1ZFU A;  2B68 A;  1B3C A;  2LKB A;  1P0A A;  2N2Q A;  4V1D C;  1ICA A;  1NH5 A;  1VNB A;  2KBK A;  2E3G A;  2NY9 X;  1SN1 A;  2LJ7 A;  4HE7 A;  2I61 A;  2BRZ A;  1GPT A;  1T1T A;  1SEG A;  1DQ7 A;  1OZZ A;  1PTX A;  1BCG A;  1ZVG A;  1I6G A;  1T0Z A;  2KGQ A;  3E7R L;  5CY0 A;  1TI5 A;  4KYP A;  2A7T A;  1JZA A;  1NRB A;  1BMR A;  2KBJ A;  5KK4 A;  1SN4 A;  1JZB A;  1BK8 A;  1GPS A;  1I6F A;  1MR4 A;  2LY5 A;  1I2U A;  2N69 A;  2KBH A;  1CN2 A;  1AYJ A;  1CHZ A;  1ZYV A;  1ZVE A;  2LR3 A;  2SN3 A;  1FH3 A;  1MYN A;  1ZU3 A;  1P00 A;  2LT8 A;  2GL1 A;  2NY8 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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