1VNAA

Proton nuclear magnetic resonance and distance geometry(slash)simulated annealing studies on the variant-1 neurotoxin from the new world scorpion centruroides sculpturatus ewing
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
65
structure length
65
Chain Sequence
KEGYLVKKSDGCKYDCFWLGKNEHCNTECKAKNQGGSYGYCYAFACWCEGLPESTPTYPLPNKSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
pubmed doi rcsb
molecule keywords NEUROTOXIN
molecule tags Neurotoxin
source organism Centruroides sculpturatus
total genus 5
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 1993-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1vnaA00
1SNBA 2BRZA 1B7DA 2KYQA 1AYJA 1BMRA 1P00A 1JXCA 1VNAA 2B68A 1MYNA 2KBKA 2N2QA 1OMYA 1NE5A 2LR3A 2YBRC 1SEGA 2N69A 2KSKA 1NH5A 1WMTA 1ZFUA 4AAZA 2NY9X 2LY5A 1CHZA 2ATBA 1I6FA 3E7UX 2KBJA 2M8BB 1NRAA 1SN4A 1B3CA 1MR4A 2LJ7A 1JKZA 2E3FA 1N4NA 1ZYWA 2KBHA 2LI7A 1T0ZA 1LQHA 2YC1C 1T7AA 2GL1A 1I2UA 5KK4A 1ICAA 3PSMA 2E3GA 1DJTA 1JZBA 4HHFA 1PE4A 2LT8A 2LY6A 2I61A 1NPIA 5CY0A 1ZVEA 1P0AA 2N2RA 2NY8X 1PTXA 1LQQA 4UJ0A 1T7BA 1I6GA 1T7EA 1ZVGA 1ZYVA 1BRZA 1NRBA 1I2VA 1L4VA 1GPTA 4V1DC 2N66A 2E0HA 1BK8A 2KJAA 1BCGA 1ZUTA 4AB0A 4KYPA 1T1TA 1KV0A 2B3CA 1SN1A 2LJMA 2MZ0A 1TI5A 1VNBA 1OZZA 1JZAA 4CQKA 4HE7A 1C55A 1C56A 2KPYA 2SN3A 4AEIA 2LKBA 1GPSA 2YEOA 3E7RL 1WWNA 2ASCA 2A7TA 1LQIA 1ZU3A 1PX9A 2KGQA 1FH3A 1DQ7A 1WT7A 1AHOA 1CN2A
chains in the Genus database with same CATH superfamily
1SNBA 1BA0A 2BRZA 5AR0A 5AQFA 5AQWA 1B7DA 3R2VA 3LDOA 2KYQA 4H5VA 2QW9A 1AYJA 1BMRA 1P00A 1JXCA 1VNAA 2B68A 3C7NA 3GKUA 3JXUA 3L6QA 1NGIA 1FH3A 1MYNA 1NGCA 3L56A 5BPLA 1HX1A 2KBKA 2QWPA 5EY4A 2QWRA 3LDNA 2N2QA 1HPMA 5BN9A 1OMYA 2QWLA 1NE5A 2LR3A 2YBRC 2YIPA 1SEGA 2E2FA 3KHWA 2N69A 2KSKA 3ATUA 1KAYA 1NH5A 1YUWA 1WMTA 1ZFUA 4AAZA 2NY9X 2LY5A 1CHZA 3BK3C 2ATBA 1I6FA 3E7UX 3FZHA 4H5TA 2KBJA 5AQSA 5BPNA 2M8BB 1NRAA 2MN5A 1KAXA 1SN4A 1B3CA 1QQOA 2VY6A 1MR4A 4H5RA 1NGFA 2LJ7A 1NGDA 5F1XA 4FSVA 5BN8A 1JKZA 5AQVA 5F2RA 2E3FA 4KBOA 1N4NA 2E88A 2JDQD 1ZYWA 2E8AA 2KBHA 2LI7A 1T0ZA 1LQHA 2YC1C 5AQIA 5AQJA 5AQPA 5FPNA 1T7AA 1BUPA 3KOZA 1NGAA 2GL1A 5AQHA 1K8BA 2QWMA 1I2UA 3D2FB 2QXLA 3FE1A 3LDLA 5KK4A 1ICAA 2G2KA 3PSMA 2E3GA 1DJTA 3IUCA 5AQNA 3CQXA 5F0XA 3KC6A 3SF4D 1JZBA 4HHFA 4H5WA 4IO8A 3A8YA 3GL1A 1PE4A 2LT8A 3FZLA 3KP0A 2QWOA 3KOXA 3L4IA 2MBKA 4UAFE 3LDQA 2LY6A 1NPIA 2I61A 5CY0A 1BA1A 1NGGA 1ZVEA 1P0AA 2N2RA 2NY8X 1NGHA 2K35A 1PTXA 1LQQA 5FPMA 3LDPA 2V7ZA 2QWQA 4UJ0A 3D2FA 1T7BA 2YILA 4H5NA 1I6GA 1T7EA 1ZVGA 1ZYVA 3D2EB 3QFUA 1POIA 5AQMA 1BRZA 1NRBA 1I2VA 3GDQA 5EXWA 1L4VA 1NGBA 1GPTA 1QQNA 2D56A 5EVZA 4V1DC 2N66A 2BUPA 3KVGA 2E0HA 3FZKA 1BK8A 5AQXA 3KOYA 5AQUA 2KJAA 2GMOA 5AQYA 1ZUTA 1BCGA 1XRSB 4AB0A 4KYPA 3ATVA 1T1TA 3CW4A 1KV0A 2B3CA 4HWIA 1NGEA 1QQMA 4GNIA 1SN1A 3D2EA 1KAZA 3QI7A 4FL9A 3M3ZA 2LJMA 3I33A 2MZ0A 3FZFA 1UGLA 5BPMA 1TI5A 5FPEA 1VNBA 1OZZA 1JZAA 4CQKA 4HE7A 5EX5A 1C55A 5AQKA 1ATRA 1C56A 2KPYA 2SN3A 4AEIA 2LKBA 1GPSA 1ATSA 5AQOA 5AQGA 2YEOA 3E7RL 3FZMA 3KP1A 4UADE 3C7NB 3HSCA 5AQZA 3QMLA 1WWNA 1S3XA 2ASCA 3QFPA 2A7TA 2KHOA 5AQTA 1LQIA 1ZU3A 5AQRA 5AQLA 5FPDA 3KOWA 1PX9A 2KGQA 1NGJA 1DKGD 1DQ7A 1HJOA 2LN8A 4UAEF 2YIOA 1WT7A 2QWNA 5AQQA 1AHOA 3AY9A 1CN2A
chains in the Genus database with same CATH topology
1SNBA 2BRZA 1B7DA 2KYQA 1AYJA 1BMRA 1P00A 1JXCA 1VNAA 2B68A 1MYNA 2KBKA 2N2QA 1OMYA 1NE5A 2LR3A 2YBRC 1SEGA 2N69A 2KSKA 1NH5A 1WMTA 1ZFUA 4AAZA 2NY9X 2LY5A 1CHZA 2ATBA 1I6FA 3E7UX 2KBJA 2M8BB 1NRAA 1SN4A 1B3CA 1MR4A 2LJ7A 1JKZA 2E3FA 1N4NA 1ZYWA 2KBHA 2LI7A 1T0ZA 1LQHA 2YC1C 1T7AA 2GL1A 1I2UA 5KK4A 1ICAA 3PSMA 2E3GA 1DJTA 1JZBA 4HHFA 1PE4A 2LT8A 2LY6A 2I61A 1NPIA 5CY0A 1ZVEA 1P0AA 2N2RA 2NY8X 1PTXA 1LQQA 4UJ0A 1T7BA 1I6GA 1T7EA 1ZVGA 1ZYVA 1BRZA 1NRBA 1I2VA 1L4VA 1GPTA 4V1DC 2N66A 2E0HA 1BK8A 2KJAA 1BCGA 1ZUTA 4AB0A 4KYPA 1T1TA 1KV0A 2B3CA 1SN1A 2LJMA 2MZ0A 1TI5A 1VNBA 1OZZA 1JZAA 4CQKA 4HE7A 1C55A 1C56A 2KPYA 2SN3A 4AEIA 2LKBA 1GPSA 2YEOA 3E7RL 1WWNA 2ASCA 2A7TA 1LQIA 1ZU3A 1PX9A 2KGQA 1FH3A 1DQ7A 1WT7A 1AHOA 1CN2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SNB A;  2BRZ A;  1B7D A;  2KYQ A;  1AYJ A;  1BMR A;  1P00 A;  1JXC A;  1VNA A;  2B68 A;  1MYN A;  2KBK A;  2N2Q A;  1OMY A;  1NE5 A;  2LR3 A;  2YBR C;  1SEG A;  2N69 A;  2KSK A;  1NH5 A;  1WMT A;  1ZFU A;  4AAZ A;  2NY9 X;  2LY5 A;  1CHZ A;  2ATB A;  1I6F A;  3E7U X;  2KBJ A;  2M8B B;  1NRA A;  1SN4 A;  1B3C A;  1MR4 A;  2LJ7 A;  1JKZ A;  2E3F A;  1N4N A;  1ZYW A;  2KBH A;  2LI7 A;  1T0Z A;  1LQH A;  2YC1 C;  1T7A A;  2GL1 A;  1I2U A;  5KK4 A;  1ICA A;  3PSM A;  2E3G A;  1DJT A;  1JZB A;  4HHF A;  1PE4 A;  2LT8 A;  2LY6 A;  2I61 A;  1NPI A;  5CY0 A;  1ZVE A;  1P0A A;  2N2R A;  2NY8 X;  1PTX A;  1LQQ A;  4UJ0 A;  1T7B A;  1I6G A;  1T7E A;  1ZVG A;  1ZYV A;  1BRZ A;  1NRB A;  1I2V A;  1L4V A;  1GPT A;  4V1D C;  2N66 A;  2E0H A;  1BK8 A;  2KJA A;  1BCG A;  1ZUT A;  4AB0 A;  4KYP A;  1T1T A;  1KV0 A;  2B3C A;  1SN1 A;  2LJM A;  2MZ0 A;  1TI5 A;  1VNB A;  1OZZ A;  1JZA A;  4CQK A;  4HE7 A;  1C55 A;  1C56 A;  2KPY A;  2SN3 A;  4AEI A;  2LKB A;  1GPS A;  2YEO A;  3E7R L;  1WWN A;  2ASC A;  2A7T A;  1LQI A;  1ZU3 A;  1PX9 A;  2KGQ A;  1FH3 A;  1DQ7 A;  1WT7 A;  1AHO A;  1CN2 A; 
#chains in the Genus database with same CATH topology
 1SNB A;  1BA0 A;  2BRZ A;  5AR0 A;  5AQF A;  5AQW A;  1B7D A;  3R2V A;  3LDO A;  2KYQ A;  4H5V A;  2QW9 A;  1AYJ A;  1BMR A;  1P00 A;  1JXC A;  1VNA A;  2B68 A;  3C7N A;  3GKU A;  3JXU A;  3L6Q A;  1NGI A;  1FH3 A;  1MYN A;  1NGC A;  3L56 A;  5BPL A;  1HX1 A;  2KBK A;  2QWP A;  5EY4 A;  2QWR A;  3LDN A;  2N2Q A;  1HPM A;  5BN9 A;  1OMY A;  2QWL A;  1NE5 A;  2LR3 A;  2YBR C;  2YIP A;  1SEG A;  2E2F A;  3KHW A;  2N69 A;  2KSK A;  3ATU A;  1KAY A;  1NH5 A;  1YUW A;  1WMT A;  1ZFU A;  4AAZ A;  2NY9 X;  2LY5 A;  1CHZ A;  3BK3 C;  2ATB A;  1I6F A;  3E7U X;  3FZH A;  4H5T A;  2KBJ A;  5AQS A;  5BPN A;  2M8B B;  1NRA A;  2MN5 A;  1KAX A;  1SN4 A;  1B3C A;  1QQO A;  2VY6 A;  1MR4 A;  4H5R A;  1NGF A;  2LJ7 A;  1NGD A;  5F1X A;  4FSV A;  5BN8 A;  1JKZ A;  5AQV A;  5F2R A;  2E3F A;  4KBO A;  1N4N A;  2E88 A;  2JDQ D;  1ZYW A;  2E8A A;  2KBH A;  2LI7 A;  1T0Z A;  1LQH A;  2YC1 C;  5AQI A;  5AQJ A;  5AQP A;  5FPN A;  1T7A A;  1BUP A;  3KOZ A;  1NGA A;  2GL1 A;  5AQH A;  1K8B A;  2QWM A;  1I2U A;  3D2F B;  2QXL A;  3FE1 A;  3LDL A;  5KK4 A;  1ICA A;  2G2K A;  3PSM A;  2E3G A;  1DJT A;  3IUC A;  5AQN A;  3CQX A;  5F0X A;  3KC6 A;  3SF4 D;  1JZB A;  4HHF A;  4H5W A;  4IO8 A;  3A8Y A;  3GL1 A;  1PE4 A;  2LT8 A;  3FZL A;  3KP0 A;  2QWO A;  3KOX A;  3L4I A;  2MBK A;  4UAF E;  3LDQ A;  2LY6 A;  1NPI A;  2I61 A;  5CY0 A;  1BA1 A;  1NGG A;  1ZVE A;  1P0A A;  2N2R A;  2NY8 X;  1NGH A;  2K35 A;  1PTX A;  1LQQ A;  5FPM A;  3LDP A;  2V7Z A;  2QWQ A;  4UJ0 A;  3D2F A;  1T7B A;  2YIL A;  4H5N A;  1I6G A;  1T7E A;  1ZVG A;  1ZYV A;  3D2E B;  3QFU A;  1POI A;  5AQM A;  1BRZ A;  1NRB A;  1I2V A;  3GDQ A;  5EXW A;  1L4V A;  1NGB A;  1GPT A;  1QQN A;  2D56 A;  5EVZ A;  4V1D C;  2N66 A;  2BUP A;  3KVG A;  2E0H A;  3FZK A;  1BK8 A;  5AQX A;  3KOY A;  5AQU A;  2KJA A;  2GMO A;  5AQY A;  1ZUT A;  1BCG A;  1XRS B;  4AB0 A;  4KYP A;  3ATV A;  1T1T A;  3CW4 A;  1KV0 A;  2B3C A;  4HWI A;  1NGE A;  1QQM A;  4GNI A;  1SN1 A;  3D2E A;  1KAZ A;  3QI7 A;  4FL9 A;  3M3Z A;  2LJM A;  3I33 A;  2MZ0 A;  3FZF A;  1UGL A;  5BPM A;  1TI5 A;  5FPE A;  1VNB A;  1OZZ A;  1JZA A;  4CQK A;  4HE7 A;  5EX5 A;  1C55 A;  5AQK A;  1ATR A;  1C56 A;  2KPY A;  2SN3 A;  4AEI A;  2LKB A;  1GPS A;  1ATS A;  5AQO A;  5AQG A;  2YEO A;  3E7R L;  3FZM A;  3KP1 A;  4UAD E;  3C7N B;  3HSC A;  5AQZ A;  3QML A;  1WWN A;  1S3X A;  2ASC A;  3QFP A;  2A7T A;  2KHO A;  5AQT A;  1LQI A;  1ZU3 A;  5AQR A;  5AQL A;  5FPD A;  3KOW A;  1PX9 A;  2KGQ A;  1NGJ A;  1DKG D;  1DQ7 A;  1HJO A;  2LN8 A;  4UAE F;  2YIO A;  1WT7 A;  2QWN A;  5AQQ A;  1AHO A;  3AY9 A;  1CN2 A; 
#chains in the Genus database with same CATH homology
 1SNB A;  2BRZ A;  1B7D A;  2KYQ A;  1AYJ A;  1BMR A;  1P00 A;  1JXC A;  1VNA A;  2B68 A;  1MYN A;  2KBK A;  2N2Q A;  1OMY A;  1NE5 A;  2LR3 A;  2YBR C;  1SEG A;  2N69 A;  2KSK A;  1NH5 A;  1WMT A;  1ZFU A;  4AAZ A;  2NY9 X;  2LY5 A;  1CHZ A;  2ATB A;  1I6F A;  3E7U X;  2KBJ A;  2M8B B;  1NRA A;  1SN4 A;  1B3C A;  1MR4 A;  2LJ7 A;  1JKZ A;  2E3F A;  1N4N A;  1ZYW A;  2KBH A;  2LI7 A;  1T0Z A;  1LQH A;  2YC1 C;  1T7A A;  2GL1 A;  1I2U A;  5KK4 A;  1ICA A;  3PSM A;  2E3G A;  1DJT A;  1JZB A;  4HHF A;  1PE4 A;  2LT8 A;  2LY6 A;  2I61 A;  1NPI A;  5CY0 A;  1ZVE A;  1P0A A;  2N2R A;  2NY8 X;  1PTX A;  1LQQ A;  4UJ0 A;  1T7B A;  1I6G A;  1T7E A;  1ZVG A;  1ZYV A;  1BRZ A;  1NRB A;  1I2V A;  1L4V A;  1GPT A;  4V1D C;  2N66 A;  2E0H A;  1BK8 A;  2KJA A;  1BCG A;  1ZUT A;  4AB0 A;  4KYP A;  1T1T A;  1KV0 A;  2B3C A;  1SN1 A;  2LJM A;  2MZ0 A;  1TI5 A;  1VNB A;  1OZZ A;  1JZA A;  4CQK A;  4HE7 A;  1C55 A;  1C56 A;  2KPY A;  2SN3 A;  4AEI A;  2LKB A;  1GPS A;  2YEO A;  3E7R L;  1WWN A;  2ASC A;  2A7T A;  1LQI A;  1ZU3 A;  1PX9 A;  2KGQ A;  1FH3 A;  1DQ7 A;  1WT7 A;  1AHO A;  1CN2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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