1KV0A

Cis/trans isomerization of non-prolyl peptide bond observed in crystal structure of an scorpion toxin
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
66
structure length
66
Chain Sequence
VRDGYIALPHNCAYGCLNNEYCNNLCTKDGAKIGYCNIVGKYGNACWCIQLPDNVPIRVPGRCHPA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Alpha-like toxin BmK-M7
total genus 15
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1kv0A00
1JZBA 1PE4A 2A7TA 5KK4A 2ATBA 2M8BB 2I61A 1JZAA 2LJ7A 1CN2A 1I2VA 2KPYA 2NY9X 1SN4A 1NE5A 1AHOA 1ZU3A 2ASCA 2SN3A 2LY5A 3E7RL 1SNBA 2LT8A 4AEIA 2KBHA 1T7EA 2N2QA 2YEOA 2MZ0A 1MYNA 1T1TA 1DQ7A 2YC1C 1B3CA 1LQIA 1C56A 1PX9A 1B7DA 1WMTA 1ZFUA 1ZUTA 1DJTA 1LQQA 2N2RA 1T7BA 1JKZA 2E3GA 2YBRC 1AYJA 2KBJA 1P00A 1CHZA 3E7UX 2GL1A 1JXCA 1I6FA 2KBKA 2NY8X 1I2UA 4V1DC 4UJ0A 1LQHA 1VNAA 1KV0A 2KSKA 2E3FA 1PTXA 2E0HA 1NRBA 1N4NA 1WWNA 1GPTA 1ZYWA 1MR4A 1SN1A 1C55A 1FH3A 1ICAA 1NRAA 1VNBA 1T0ZA 5CY0A 1BCGA 4AB0A 2KJAA 1ZVGA 2LKBA 2BRZA 1BRZA 1OZZA 1T7AA 2LR3A 2B68A 4HE7A 1L4VA 1ZYVA 2LI7A 2B3CA 1OMYA 1WT7A 1BMRA 2LY6A 1GPSA 2LJMA 2KGQA 1NPIA 4AAZA 4KYPA 2N66A 1TI5A 2KYQA 2N69A 1I6GA 4CQKA 1ZVEA 1BK8A 1NH5A 1P0AA 1SEGA 4HHFA 3PSMA
chains in the Genus database with same CATH superfamily
4H5WA 1JZBA 4H5NA 5AQLA 1PE4A 3KOXA 4GNIA 3QFUA 2QWMA 3R2VA 5AR0A 5AQVA 3GL1A 5AQQA 1NGFA 1L4VA 2A7TA 5KK4A 4UADE 2LN8A 2KHOA 5AQUA 4IO8A 3I33A 1S3XA 3QFPA 4UAFE 2ATBA 1NGCA 2I61A 1JZAA 2M8BB 1KAXA 1ATRA 5AQZA 2LJ7A 3IUCA 5BPLA 3LDOA 3AY9A 1CN2A 1I2VA 2KPYA 5EX5A 2QWQA 2NY9X 1NGDA 4H5VA 3L4IA 5FPMA 1SN4A 3D2FB 5F1XA 1NE5A 1AHOA 1QQNA 5AQMA 1ZU3A 2ASCA 1KAYA 2LY5A 2SN3A 1SNBA 2LT8A 3E7RL 4AEIA 1XRSB 2KBHA 4H5RA 1T7EA 2N2QA 3FZKA 2YEOA 5AQTA 3L56A 2MZ0A 1MYNA 2QXLA 2QWLA 1T1TA 5BN9A 2QWRA 3SF4D 1DQ7A 3LDPA 2YC1C 5EVZA 1B3CA 1K8BA 1LQIA 3KOZA 2QWPA 1NGAA 3A8YA 5F2RA 1C56A 1PX9A 1B7DA 2D56A 1WMTA 3L6QA 1ZFUA 1BA1A 1ZUTA 2MN5A 3D2EA 1DJTA 3GDQA 1LQQA 2N2RA 5AQSA 2QWNA 1T7BA 5FPNA 1JKZA 1HX1A 2G2KA 3ATUA 5AQPA 3CQXA 2E3GA 2VY6A 2YBRC 3C7NA 1AYJA 2KBJA 1P00A 1ATSA 1NGHA 1NGBA 1CHZA 3FZLA 5AQRA 5AQJA 5AQYA 4HWIA 3E7UX 3KHWA 1NGIA 5AQIA 2GL1A 5AQKA 1JXCA 1KAZA 3CW4A 2JDQD 5FPEA 5F0XA 2GMOA 1I6FA 2KBKA 2BUPA 2YIPA 3KOWA 2NY8X 5AQGA 5FPDA 3ATVA 1POIA 1I2UA 3LDNA 3KP1A 4V1DC 4UJ0A 1LQHA 1DKGD 1VNAA 3KOYA 1KV0A 4UAEF 2KSKA 3BK3C 2E3FA 1PTXA 5EY4A 2E0HA 5BPNA 1NRBA 1N4NA 1WWNA 1GPTA 1ZYWA 2MBKA 1MR4A 4H5TA 3D2EB 1SN1A 1C55A 1FH3A 5AQWA 2YILA 1NRAA 1VNBA 1ICAA 1T0ZA 5CY0A 5BN8A 1QQOA 3C7NB 1BCGA 3HSCA 5AQNA 3FZMA 3KC6A 3KP0A 4KBOA 4AB0A 2KJAA 1BUPA 1ZVGA 2LKBA 3QMLA 2BRZA 2V7ZA 1BRZA 1OZZA 2YIOA 1UGLA 3KVGA 3LDLA 2E88A 5AQFA 2E8AA 5BPMA 2K35A 1BA0A 3FZFA 1T7AA 1QQMA 2B68A 2E2FA 2LR3A 3M3ZA 4HE7A 5AQOA 1NGJA 1ZYVA 5AQHA 2LI7A 1HJOA 1OMYA 2B3CA 1WT7A 2QW9A 2LY6A 3GKUA 5AQXA 3D2FA 1BMRA 1GPSA 2LJMA 2QWOA 2KGQA 1NPIA 4AAZA 3FZHA 3QI7A 5EXWA 1YUWA 4KYPA 2N66A 1TI5A 2KYQA 2N69A 1I6GA 3FE1A 4CQKA 1ZVEA 1NGEA 1HPMA 4FSVA 1BK8A 3JXUA 4FL9A 1NH5A 1P0AA 1NGGA 1SEGA 3LDQA 4HHFA 3PSMA
chains in the Genus database with same CATH topology
1JZBA 1PE4A 2A7TA 5KK4A 2ATBA 2M8BB 2I61A 1JZAA 2LJ7A 1CN2A 1I2VA 2KPYA 2NY9X 1SN4A 1NE5A 1AHOA 1ZU3A 2ASCA 2SN3A 2LY5A 3E7RL 1SNBA 2LT8A 4AEIA 2KBHA 1T7EA 2N2QA 2YEOA 2MZ0A 1MYNA 1T1TA 1DQ7A 2YC1C 1B3CA 1LQIA 1C56A 1PX9A 1B7DA 1WMTA 1ZFUA 1ZUTA 1DJTA 1LQQA 2N2RA 1T7BA 1JKZA 2E3GA 2YBRC 1AYJA 2KBJA 1P00A 1CHZA 3E7UX 2GL1A 1JXCA 1I6FA 2KBKA 2NY8X 1I2UA 4V1DC 4UJ0A 1LQHA 1VNAA 1KV0A 2KSKA 2E3FA 1PTXA 2E0HA 1NRBA 1N4NA 1WWNA 1GPTA 1ZYWA 1MR4A 1SN1A 1C55A 1FH3A 1ICAA 1NRAA 1VNBA 1T0ZA 5CY0A 1BCGA 4AB0A 2KJAA 1ZVGA 2LKBA 2BRZA 1BRZA 1OZZA 1T7AA 2LR3A 2B68A 4HE7A 1L4VA 1ZYVA 2LI7A 2B3CA 1OMYA 1WT7A 1BMRA 2LY6A 1GPSA 2LJMA 2KGQA 1NPIA 4AAZA 4KYPA 2N66A 1TI5A 2KYQA 2N69A 1I6GA 4CQKA 1ZVEA 1BK8A 1NH5A 1P0AA 1SEGA 4HHFA 3PSMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JZB A;  1PE4 A;  2A7T A;  5KK4 A;  2ATB A;  2M8B B;  2I61 A;  1JZA A;  2LJ7 A;  1CN2 A;  1I2V A;  2KPY A;  2NY9 X;  1SN4 A;  1NE5 A;  1AHO A;  1ZU3 A;  2ASC A;  2SN3 A;  2LY5 A;  3E7R L;  1SNB A;  2LT8 A;  4AEI A;  2KBH A;  1T7E A;  2N2Q A;  2YEO A;  2MZ0 A;  1MYN A;  1T1T A;  1DQ7 A;  2YC1 C;  1B3C A;  1LQI A;  1C56 A;  1PX9 A;  1B7D A;  1WMT A;  1ZFU A;  1ZUT A;  1DJT A;  1LQQ A;  2N2R A;  1T7B A;  1JKZ A;  2E3G A;  2YBR C;  1AYJ A;  2KBJ A;  1P00 A;  1CHZ A;  3E7U X;  2GL1 A;  1JXC A;  1I6F A;  2KBK A;  2NY8 X;  1I2U A;  4V1D C;  4UJ0 A;  1LQH A;  1VNA A;  1KV0 A;  2KSK A;  2E3F A;  1PTX A;  2E0H A;  1NRB A;  1N4N A;  1WWN A;  1GPT A;  1ZYW A;  1MR4 A;  1SN1 A;  1C55 A;  1FH3 A;  1ICA A;  1NRA A;  1VNB A;  1T0Z A;  5CY0 A;  1BCG A;  4AB0 A;  2KJA A;  1ZVG A;  2LKB A;  2BRZ A;  1BRZ A;  1OZZ A;  1T7A A;  2LR3 A;  2B68 A;  4HE7 A;  1L4V A;  1ZYV A;  2LI7 A;  2B3C A;  1OMY A;  1WT7 A;  1BMR A;  2LY6 A;  1GPS A;  2LJM A;  2KGQ A;  1NPI A;  4AAZ A;  4KYP A;  2N66 A;  1TI5 A;  2KYQ A;  2N69 A;  1I6G A;  4CQK A;  1ZVE A;  1BK8 A;  1NH5 A;  1P0A A;  1SEG A;  4HHF A;  3PSM A; 
#chains in the Genus database with same CATH topology
 4H5W A;  1JZB A;  4H5N A;  5AQL A;  1PE4 A;  3KOX A;  4GNI A;  3QFU A;  2QWM A;  3R2V A;  5AR0 A;  5AQV A;  3GL1 A;  5AQQ A;  1NGF A;  1L4V A;  2A7T A;  5KK4 A;  4UAD E;  2LN8 A;  2KHO A;  5AQU A;  4IO8 A;  3I33 A;  1S3X A;  3QFP A;  4UAF E;  2ATB A;  1NGC A;  2I61 A;  1JZA A;  2M8B B;  1KAX A;  1ATR A;  5AQZ A;  2LJ7 A;  3IUC A;  5BPL A;  3LDO A;  3AY9 A;  1CN2 A;  1I2V A;  2KPY A;  5EX5 A;  2QWQ A;  2NY9 X;  1NGD A;  4H5V A;  3L4I A;  5FPM A;  1SN4 A;  3D2F B;  5F1X A;  1NE5 A;  1AHO A;  1QQN A;  5AQM A;  1ZU3 A;  2ASC A;  1KAY A;  2LY5 A;  2SN3 A;  1SNB A;  2LT8 A;  3E7R L;  4AEI A;  1XRS B;  2KBH A;  4H5R A;  1T7E A;  2N2Q A;  3FZK A;  2YEO A;  5AQT A;  3L56 A;  2MZ0 A;  1MYN A;  2QXL A;  2QWL A;  1T1T A;  5BN9 A;  2QWR A;  3SF4 D;  1DQ7 A;  3LDP A;  2YC1 C;  5EVZ A;  1B3C A;  1K8B A;  1LQI A;  3KOZ A;  2QWP A;  1NGA A;  3A8Y A;  5F2R A;  1C56 A;  1PX9 A;  1B7D A;  2D56 A;  1WMT A;  3L6Q A;  1ZFU A;  1BA1 A;  1ZUT A;  2MN5 A;  3D2E A;  1DJT A;  3GDQ A;  1LQQ A;  2N2R A;  5AQS A;  2QWN A;  1T7B A;  5FPN A;  1JKZ A;  1HX1 A;  2G2K A;  3ATU A;  5AQP A;  3CQX A;  2E3G A;  2VY6 A;  2YBR C;  3C7N A;  1AYJ A;  2KBJ A;  1P00 A;  1ATS A;  1NGH A;  1NGB A;  1CHZ A;  3FZL A;  5AQR A;  5AQJ A;  5AQY A;  4HWI A;  3E7U X;  3KHW A;  1NGI A;  5AQI A;  2GL1 A;  5AQK A;  1JXC A;  1KAZ A;  3CW4 A;  2JDQ D;  5FPE A;  5F0X A;  2GMO A;  1I6F A;  2KBK A;  2BUP A;  2YIP A;  3KOW A;  2NY8 X;  5AQG A;  5FPD A;  3ATV A;  1POI A;  1I2U A;  3LDN A;  3KP1 A;  4V1D C;  4UJ0 A;  1LQH A;  1DKG D;  1VNA A;  3KOY A;  1KV0 A;  4UAE F;  2KSK A;  3BK3 C;  2E3F A;  1PTX A;  5EY4 A;  2E0H A;  5BPN A;  1NRB A;  1N4N A;  1WWN A;  1GPT A;  1ZYW A;  2MBK A;  1MR4 A;  4H5T A;  3D2E B;  1SN1 A;  1C55 A;  1FH3 A;  5AQW A;  2YIL A;  1NRA A;  1VNB A;  1ICA A;  1T0Z A;  5CY0 A;  5BN8 A;  1QQO A;  3C7N B;  1BCG A;  3HSC A;  5AQN A;  3FZM A;  3KC6 A;  3KP0 A;  4KBO A;  4AB0 A;  2KJA A;  1BUP A;  1ZVG A;  2LKB A;  3QML A;  2BRZ A;  2V7Z A;  1BRZ A;  1OZZ A;  2YIO A;  1UGL A;  3KVG A;  3LDL A;  2E88 A;  5AQF A;  2E8A A;  5BPM A;  2K35 A;  1BA0 A;  3FZF A;  1T7A A;  1QQM A;  2B68 A;  2E2F A;  2LR3 A;  3M3Z A;  4HE7 A;  5AQO A;  1NGJ A;  1ZYV A;  5AQH A;  2LI7 A;  1HJO A;  1OMY A;  2B3C A;  1WT7 A;  2QW9 A;  2LY6 A;  3GKU A;  5AQX A;  3D2F A;  1BMR A;  1GPS A;  2LJM A;  2QWO A;  2KGQ A;  1NPI A;  4AAZ A;  3FZH A;  3QI7 A;  5EXW A;  1YUW A;  4KYP A;  2N66 A;  1TI5 A;  2KYQ A;  2N69 A;  1I6G A;  3FE1 A;  4CQK A;  1ZVE A;  1NGE A;  1HPM A;  4FSV A;  1BK8 A;  3JXU A;  4FL9 A;  1NH5 A;  1P0A A;  1NGG A;  1SEG A;  3LDQ A;  4HHF A;  3PSM A; 
#chains in the Genus database with same CATH homology
 1JZB A;  1PE4 A;  2A7T A;  5KK4 A;  2ATB A;  2M8B B;  2I61 A;  1JZA A;  2LJ7 A;  1CN2 A;  1I2V A;  2KPY A;  2NY9 X;  1SN4 A;  1NE5 A;  1AHO A;  1ZU3 A;  2ASC A;  2SN3 A;  2LY5 A;  3E7R L;  1SNB A;  2LT8 A;  4AEI A;  2KBH A;  1T7E A;  2N2Q A;  2YEO A;  2MZ0 A;  1MYN A;  1T1T A;  1DQ7 A;  2YC1 C;  1B3C A;  1LQI A;  1C56 A;  1PX9 A;  1B7D A;  1WMT A;  1ZFU A;  1ZUT A;  1DJT A;  1LQQ A;  2N2R A;  1T7B A;  1JKZ A;  2E3G A;  2YBR C;  1AYJ A;  2KBJ A;  1P00 A;  1CHZ A;  3E7U X;  2GL1 A;  1JXC A;  1I6F A;  2KBK A;  2NY8 X;  1I2U A;  4V1D C;  4UJ0 A;  1LQH A;  1VNA A;  1KV0 A;  2KSK A;  2E3F A;  1PTX A;  2E0H A;  1NRB A;  1N4N A;  1WWN A;  1GPT A;  1ZYW A;  1MR4 A;  1SN1 A;  1C55 A;  1FH3 A;  1ICA A;  1NRA A;  1VNB A;  1T0Z A;  5CY0 A;  1BCG A;  4AB0 A;  2KJA A;  1ZVG A;  2LKB A;  2BRZ A;  1BRZ A;  1OZZ A;  1T7A A;  2LR3 A;  2B68 A;  4HE7 A;  1L4V A;  1ZYV A;  2LI7 A;  2B3C A;  1OMY A;  1WT7 A;  1BMR A;  2LY6 A;  1GPS A;  2LJM A;  2KGQ A;  1NPI A;  4AAZ A;  4KYP A;  2N66 A;  1TI5 A;  2KYQ A;  2N69 A;  1I6G A;  4CQK A;  1ZVE A;  1BK8 A;  1NH5 A;  1P0A A;  1SEG A;  4HHF A;  3PSM A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...