5CY0A

Total chemical synthesis, covalent structure verification, and x-ray structure of bioactive ts3 toxin by racemic protein crystallography
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
63
structure length
63
Chain Sequence
KKDGYPVEYDNCAYICWNYDNAYCDKLCKDKKADSGYCYWVHILCYCYGLPDSEPTKTNGKCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
pubmed doi rcsb
molecule keywords Ts3 Toxin
molecule tags Toxin
total genus 16
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2015-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 5cy0A00
1VNAA 1SEGA 4HHFA 1DQ7A 2MZ0A 2KBKA 1CHZA 1NE5A 2I61A 2N2QA 1PTXA 1ZUTA 1JXCA 2E0HA 2YC1C 1BRZA 1DJTA 1BK8A 2KBHA 2LJ7A 1I6GA 1NRBA 1OMYA 5CY0A 1T7AA 1WT7A 1GPSA 2N2RA 4HE7A 1SNBA 1L4VA 1ZYWA 1AYJA 2BRZA 5KK4A 1ICAA 1P0AA 2SN3A 1B3CA 2LY5A 1T1TA 2LY6A 3E7UX 1I2VA 1NRAA 1KV0A 2LJMA 1JKZA 1LQHA 2E3FA 2NY8X 4CQKA 1P00A 2KPYA 1ZVEA 1T0ZA 2ATBA 2M8BB 4AB0A 1NPIA 3E7RL 2B68A 4AAZA 1ZFUA 1MYNA 1I6FA 1NH5A 1MR4A 1ZYVA 2GL1A 3PSMA 2N66A 1WWNA 2B3CA 1JZAA 1OZZA 1SN1A 1T7EA 1BCGA 1N4NA 1B7DA 2E3GA 1CN2A 2KSKA 2KYQA 1C56A 2NY9X 1I2UA 1ZU3A 1LQQA 1GPTA 1PE4A 2LKBA 2KGQA 2LR3A 1AHOA 2KBJA 2YBRC 1JZBA 4KYPA 1WMTA 2N69A 2KJAA 2A7TA 2ASCA 1PX9A 1TI5A 1VNBA 1LQIA 4UJ0A 4V1DC 1BMRA 2YEOA 4AEIA 1ZVGA 1C55A 1FH3A 2LI7A 2LT8A 1SN4A 1T7BA
chains in the Genus database with same CATH superfamily
1VNAA 5AQRA 1NGFA 1KAYA 1QQNA 1SEGA 4HHFA 5F2RA 1DQ7A 2MZ0A 2KBKA 3D2FA 1CHZA 1NE5A 2QWMA 2I61A 2N2QA 3GL1A 1PTXA 2G2KA 1ZUTA 4H5WA 5AQYA 1JXCA 1NGHA 2E0HA 2QWOA 2YC1C 3AY9A 5AQHA 1BRZA 1KAZA 5EX5A 3D2FB 3I33A 3LDPA 5EY4A 1NGGA 5FPMA 1DJTA 2YILA 1BK8A 5AQSA 4H5NA 2KBHA 2LJ7A 1I6GA 1QQMA 1NRBA 1OMYA 3FZKA 4FSVA 1L4VA 5CY0A 1T7AA 1CN2A 3FZHA 3IUCA 1WT7A 1GPSA 3D2EA 1HJOA 2N2RA 1SNBA 4HE7A 1ZYWA 3FZLA 5AQNA 3JXUA 1AYJA 2BRZA 3KOZA 2KHOA 1P0AA 5KK4A 1ICAA 2GMOA 2SN3A 5AQLA 1B3CA 2YIPA 3A8YA 1HPMA 2LY5A 1T1TA 2LY6A 3ATVA 3E7UX 2MN5A 2MBKA 2YIOA 1NRAA 5AQWA 3FZFA 4UADE 5F1XA 1I2VA 1NGDA 3KP0A 1KV0A 2LJMA 1JKZA 1NGBA 5AQQA 2D56A 1LQHA 3HSCA 2E3FA 5AQZA 5FPDA 2NY8X 4CQKA 5BN8A 1P00A 5BN9A 5AQIA 4GNIA 2KPYA 1ZVEA 4UAFE 3LDOA 1HX1A 1S3XA 1T0ZA 3GDQA 2ATBA 5AQFA 2M8BB 2QWLA 2BUPA 4AB0A 4IO8A 5BPMA 1NPIA 3E7RL 4FL9A 5AQXA 3FZMA 2B68A 2V7ZA 4H5TA 4AAZA 5F0XA 1BA0A 1ZFUA 2QWRA 2QWPA 1K8BA 1MYNA 1POIA 3GKUA 5AQVA 5AQPA 1I6FA 5AQMA 2E88A 3CQXA 3BK3C 3KOYA 3LDNA 1NH5A 3L6QA 1MR4A 4HWIA 2QWNA 1ZYVA 2E2FA 2GL1A 3D2EB 2E8AA 2QW9A 3PSMA 5AQUA 1KAXA 2N66A 1WWNA 3QFUA 3KP1A 2B3CA 1JZAA 1OZZA 1SN1A 1ATSA 1T7EA 1BCGA 1N4NA 5BPNA 3KOXA 5AQKA 4UAEF 1B7DA 3ATUA 5AQGA 3KVGA 2E3GA 3C7NA 3QMLA 5EVZA 2KSKA 1BA1A 2KYQA 1NGCA 2JDQD 3L4IA 3R2VA 4H5RA 5AR0A 1C56A 2NY9X 3KOWA 1I2UA 1ZU3A 2QWQA 3QFPA 5AQOA 1LQQA 2QXLA 1YUWA 1GPTA 1PE4A 2LKBA 2KGQA 3M3ZA 2LR3A 1AHOA 2KBJA 5FPNA 2YBRC 1BUPA 3CW4A 1JZBA 4KYPA 1WMTA 3LDQA 1NGAA 2N69A 2KJAA 2A7TA 2ASCA 3KC6A 1PX9A 1TI5A 1UGLA 1VNBA 1LQIA 1NGEA 5AQJA 1QQOA 5FPEA 4KBOA 4UJ0A 4V1DC 1BMRA 1DKGD 2VY6A 2YEOA 4AEIA 1ATRA 1ZVGA 3SF4D 1C55A 2LN8A 5EXWA 1FH3A 3QI7A 1NGJA 1NGIA 2LI7A 2LT8A 3FE1A 3L56A 1XRSB 5AQTA 5BPLA 1SN4A 3LDLA 3C7NB 3KHWA 4H5VA 2K35A 1T7BA
chains in the Genus database with same CATH topology
1VNAA 1SEGA 4HHFA 1DQ7A 2MZ0A 2KBKA 1CHZA 1NE5A 2I61A 2N2QA 1PTXA 1ZUTA 1JXCA 2E0HA 2YC1C 1BRZA 1DJTA 1BK8A 2KBHA 2LJ7A 1I6GA 1NRBA 1OMYA 5CY0A 1T7AA 1WT7A 1GPSA 2N2RA 4HE7A 1SNBA 1L4VA 1ZYWA 1AYJA 2BRZA 5KK4A 1ICAA 1P0AA 2SN3A 1B3CA 2LY5A 1T1TA 2LY6A 3E7UX 1I2VA 1NRAA 1KV0A 2LJMA 1JKZA 1LQHA 2E3FA 2NY8X 4CQKA 1P00A 2KPYA 1ZVEA 1T0ZA 2ATBA 2M8BB 4AB0A 1NPIA 3E7RL 2B68A 4AAZA 1ZFUA 1MYNA 1I6FA 1NH5A 1MR4A 1ZYVA 2GL1A 3PSMA 2N66A 1WWNA 2B3CA 1JZAA 1OZZA 1SN1A 1T7EA 1BCGA 1N4NA 1B7DA 2E3GA 1CN2A 2KSKA 2KYQA 1C56A 2NY9X 1I2UA 1ZU3A 1LQQA 1GPTA 1PE4A 2LKBA 2KGQA 2LR3A 1AHOA 2KBJA 2YBRC 1JZBA 4KYPA 1WMTA 2N69A 2KJAA 2A7TA 2ASCA 1PX9A 1TI5A 1VNBA 1LQIA 4UJ0A 4V1DC 1BMRA 2YEOA 4AEIA 1ZVGA 1C55A 1FH3A 2LI7A 2LT8A 1SN4A 1T7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VNA A;  1SEG A;  4HHF A;  1DQ7 A;  2MZ0 A;  2KBK A;  1CHZ A;  1NE5 A;  2I61 A;  2N2Q A;  1PTX A;  1ZUT A;  1JXC A;  2E0H A;  2YC1 C;  1BRZ A;  1DJT A;  1BK8 A;  2KBH A;  2LJ7 A;  1I6G A;  1NRB A;  1OMY A;  5CY0 A;  1T7A A;  1WT7 A;  1GPS A;  2N2R A;  4HE7 A;  1SNB A;  1L4V A;  1ZYW A;  1AYJ A;  2BRZ A;  5KK4 A;  1ICA A;  1P0A A;  2SN3 A;  1B3C A;  2LY5 A;  1T1T A;  2LY6 A;  3E7U X;  1I2V A;  1NRA A;  1KV0 A;  2LJM A;  1JKZ A;  1LQH A;  2E3F A;  2NY8 X;  4CQK A;  1P00 A;  2KPY A;  1ZVE A;  1T0Z A;  2ATB A;  2M8B B;  4AB0 A;  1NPI A;  3E7R L;  2B68 A;  4AAZ A;  1ZFU A;  1MYN A;  1I6F A;  1NH5 A;  1MR4 A;  1ZYV A;  2GL1 A;  3PSM A;  2N66 A;  1WWN A;  2B3C A;  1JZA A;  1OZZ A;  1SN1 A;  1T7E A;  1BCG A;  1N4N A;  1B7D A;  2E3G A;  1CN2 A;  2KSK A;  2KYQ A;  1C56 A;  2NY9 X;  1I2U A;  1ZU3 A;  1LQQ A;  1GPT A;  1PE4 A;  2LKB A;  2KGQ A;  2LR3 A;  1AHO A;  2KBJ A;  2YBR C;  1JZB A;  4KYP A;  1WMT A;  2N69 A;  2KJA A;  2A7T A;  2ASC A;  1PX9 A;  1TI5 A;  1VNB A;  1LQI A;  4UJ0 A;  4V1D C;  1BMR A;  2YEO A;  4AEI A;  1ZVG A;  1C55 A;  1FH3 A;  2LI7 A;  2LT8 A;  1SN4 A;  1T7B A; 
#chains in the Genus database with same CATH topology
 1VNA A;  5AQR A;  1NGF A;  1KAY A;  1QQN A;  1SEG A;  4HHF A;  5F2R A;  1DQ7 A;  2MZ0 A;  2KBK A;  3D2F A;  1CHZ A;  1NE5 A;  2QWM A;  2I61 A;  2N2Q A;  3GL1 A;  1PTX A;  2G2K A;  1ZUT A;  4H5W A;  5AQY A;  1JXC A;  1NGH A;  2E0H A;  2QWO A;  2YC1 C;  3AY9 A;  5AQH A;  1BRZ A;  1KAZ A;  5EX5 A;  3D2F B;  3I33 A;  3LDP A;  5EY4 A;  1NGG A;  5FPM A;  1DJT A;  2YIL A;  1BK8 A;  5AQS A;  4H5N A;  2KBH A;  2LJ7 A;  1I6G A;  1QQM A;  1NRB A;  1OMY A;  3FZK A;  4FSV A;  1L4V A;  5CY0 A;  1T7A A;  1CN2 A;  3FZH A;  3IUC A;  1WT7 A;  1GPS A;  3D2E A;  1HJO A;  2N2R A;  1SNB A;  4HE7 A;  1ZYW A;  3FZL A;  5AQN A;  3JXU A;  1AYJ A;  2BRZ A;  3KOZ A;  2KHO A;  1P0A A;  5KK4 A;  1ICA A;  2GMO A;  2SN3 A;  5AQL A;  1B3C A;  2YIP A;  3A8Y A;  1HPM A;  2LY5 A;  1T1T A;  2LY6 A;  3ATV A;  3E7U X;  2MN5 A;  2MBK A;  2YIO A;  1NRA A;  5AQW A;  3FZF A;  4UAD E;  5F1X A;  1I2V A;  1NGD A;  3KP0 A;  1KV0 A;  2LJM A;  1JKZ A;  1NGB A;  5AQQ A;  2D56 A;  1LQH A;  3HSC A;  2E3F A;  5AQZ A;  5FPD A;  2NY8 X;  4CQK A;  5BN8 A;  1P00 A;  5BN9 A;  5AQI A;  4GNI A;  2KPY A;  1ZVE A;  4UAF E;  3LDO A;  1HX1 A;  1S3X A;  1T0Z A;  3GDQ A;  2ATB A;  5AQF A;  2M8B B;  2QWL A;  2BUP A;  4AB0 A;  4IO8 A;  5BPM A;  1NPI A;  3E7R L;  4FL9 A;  5AQX A;  3FZM A;  2B68 A;  2V7Z A;  4H5T A;  4AAZ A;  5F0X A;  1BA0 A;  1ZFU A;  2QWR A;  2QWP A;  1K8B A;  1MYN A;  1POI A;  3GKU A;  5AQV A;  5AQP A;  1I6F A;  5AQM A;  2E88 A;  3CQX A;  3BK3 C;  3KOY A;  3LDN A;  1NH5 A;  3L6Q A;  1MR4 A;  4HWI A;  2QWN A;  1ZYV A;  2E2F A;  2GL1 A;  3D2E B;  2E8A A;  2QW9 A;  3PSM A;  5AQU A;  1KAX A;  2N66 A;  1WWN A;  3QFU A;  3KP1 A;  2B3C A;  1JZA A;  1OZZ A;  1SN1 A;  1ATS A;  1T7E A;  1BCG A;  1N4N A;  5BPN A;  3KOX A;  5AQK A;  4UAE F;  1B7D A;  3ATU A;  5AQG A;  3KVG A;  2E3G A;  3C7N A;  3QML A;  5EVZ A;  2KSK A;  1BA1 A;  2KYQ A;  1NGC A;  2JDQ D;  3L4I A;  3R2V A;  4H5R A;  5AR0 A;  1C56 A;  2NY9 X;  3KOW A;  1I2U A;  1ZU3 A;  2QWQ A;  3QFP A;  5AQO A;  1LQQ A;  2QXL A;  1YUW A;  1GPT A;  1PE4 A;  2LKB A;  2KGQ A;  3M3Z A;  2LR3 A;  1AHO A;  2KBJ A;  5FPN A;  2YBR C;  1BUP A;  3CW4 A;  1JZB A;  4KYP A;  1WMT A;  3LDQ A;  1NGA A;  2N69 A;  2KJA A;  2A7T A;  2ASC A;  3KC6 A;  1PX9 A;  1TI5 A;  1UGL A;  1VNB A;  1LQI A;  1NGE A;  5AQJ A;  1QQO A;  5FPE A;  4KBO A;  4UJ0 A;  4V1D C;  1BMR A;  1DKG D;  2VY6 A;  2YEO A;  4AEI A;  1ATR A;  1ZVG A;  3SF4 D;  1C55 A;  2LN8 A;  5EXW A;  1FH3 A;  3QI7 A;  1NGJ A;  1NGI A;  2LI7 A;  2LT8 A;  3FE1 A;  3L56 A;  1XRS B;  5AQT A;  5BPL A;  1SN4 A;  3LDL A;  3C7N B;  3KHW A;  4H5V A;  2K35 A;  1T7B A; 
#chains in the Genus database with same CATH homology
 1VNA A;  1SEG A;  4HHF A;  1DQ7 A;  2MZ0 A;  2KBK A;  1CHZ A;  1NE5 A;  2I61 A;  2N2Q A;  1PTX A;  1ZUT A;  1JXC A;  2E0H A;  2YC1 C;  1BRZ A;  1DJT A;  1BK8 A;  2KBH A;  2LJ7 A;  1I6G A;  1NRB A;  1OMY A;  5CY0 A;  1T7A A;  1WT7 A;  1GPS A;  2N2R A;  4HE7 A;  1SNB A;  1L4V A;  1ZYW A;  1AYJ A;  2BRZ A;  5KK4 A;  1ICA A;  1P0A A;  2SN3 A;  1B3C A;  2LY5 A;  1T1T A;  2LY6 A;  3E7U X;  1I2V A;  1NRA A;  1KV0 A;  2LJM A;  1JKZ A;  1LQH A;  2E3F A;  2NY8 X;  4CQK A;  1P00 A;  2KPY A;  1ZVE A;  1T0Z A;  2ATB A;  2M8B B;  4AB0 A;  1NPI A;  3E7R L;  2B68 A;  4AAZ A;  1ZFU A;  1MYN A;  1I6F A;  1NH5 A;  1MR4 A;  1ZYV A;  2GL1 A;  3PSM A;  2N66 A;  1WWN A;  2B3C A;  1JZA A;  1OZZ A;  1SN1 A;  1T7E A;  1BCG A;  1N4N A;  1B7D A;  2E3G A;  1CN2 A;  2KSK A;  2KYQ A;  1C56 A;  2NY9 X;  1I2U A;  1ZU3 A;  1LQQ A;  1GPT A;  1PE4 A;  2LKB A;  2KGQ A;  2LR3 A;  1AHO A;  2KBJ A;  2YBR C;  1JZB A;  4KYP A;  1WMT A;  2N69 A;  2KJA A;  2A7T A;  2ASC A;  1PX9 A;  1TI5 A;  1VNB A;  1LQI A;  4UJ0 A;  4V1D C;  1BMR A;  2YEO A;  4AEI A;  1ZVG A;  1C55 A;  1FH3 A;  2LI7 A;  2LT8 A;  1SN4 A;  1T7B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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