1P00A

Nmr structure of etd151, mutant of the antifungal defensin ard1 from archaeoprepona demophon
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSNCRAECKRRGYKGGHCGSFANVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lead optimization of antifungal peptides with 3D NMR structures analysis.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Archaeoprepona demophon
molecule keywords defensin ARD1
total genus 7
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2003-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1p00A00
4AAZA 2N2RA 1VNBA 1AHOA 1SEGA 4V1DC 1I2VA 1AYJA 1PE4A 1MR4A 2KGQA 1BMRA 2KBKA 2B68A 2YEOA 1ZUTA 1WT7A 2B3CA 2YBRC 1JZAA 2N2QA 4HE7A 4AB0A 1I6FA 1T1TA 2LR3A 1PX9A 1CN2A 2LKBA 4KYPA 1NH5A 1FH3A 1T7AA 1P0AA 2A7TA 4HHFA 2N69A 1N4NA 1ZVEA 1JXCA 1LQIA 2BRZA 1B7DA 1P00A 2LJ7A 2LT8A 5CY0A 2KYQA 1JKZA 2LY6A 1T7EA 1BCGA 2E3GA 3PSMA 2KPYA 4AEIA 2E3FA 1NE5A 2LI7A 2ATBA 2LY5A 2MZ0A 1SN4A 2N66A 5KK4A 1PTXA 1JZBA 1KV0A 1CHZA 1DJTA 1VNAA 1L4VA 2E0HA 2I61A 1GPTA 2GL1A 1T7BA 1ZYWA 1TI5A 2NY9X 3E7UX 1BK8A 1C56A 1ZFUA 4UJ0A 2YC1C 1WMTA 1ZYVA 1T0ZA 2NY8X 4CQKA 1BRZA 2ASCA 1I2UA 1OZZA 1NPIA 2KBJA 1SN1A 1ZVGA 2KJAA 1B3CA 1LQHA 1C55A 3E7RL 1NRAA 2LJMA 2M8BB 1DQ7A 2KSKA 1OMYA 1MYNA 1WWNA 2SN3A 1ZU3A 1GPSA 2KBHA 1NRBA 1LQQA 1I6GA 1SNBA 1ICAA
chains in the Genus database with same CATH superfamily
3CQXA 2N2RA 2QW9A 4AAZA 4H5RA 1VNBA 1ICAA 1AHOA 1SEGA 2YIOA 3FZLA 4V1DC 3CW4A 1I2VA 5BPMA 3QFPA 1AYJA 1PE4A 1MR4A 2KGQA 1BMRA 2KBKA 2B68A 2YEOA 3M3ZA 2D56A 1ZUTA 2KHOA 5EXWA 1WT7A 1NGGA 2B3CA 4UAFE 3QI7A 1NGDA 5EVZA 2QWRA 2YBRC 5AQTA 1JZAA 1NGAA 3L6QA 2N2QA 3FZFA 2QWLA 1BA0A 3L4IA 1ATSA 2LN8A 1YUWA 3KC6A 4HE7A 5EY4A 4AB0A 1I6FA 2VY6A 3FZMA 1T1TA 1NGIA 2LR3A 1PX9A 3IUCA 3LDPA 3KOZA 5BN9A 1CN2A 1KAYA 1POIA 2LKBA 4KBOA 3HSCA 4KYPA 5AQNA 2YIPA 3BK3C 3I33A 1NH5A 2MBKA 1NGCA 2K35A 3ATUA 3KVGA 1T7AA 1QQNA 1P0AA 5AQPA 5F0XA 1FH3A 2QWOA 2A7TA 5FPMA 2E2FA 4FSVA 1NGJA 2N69A 1N4NA 1ZVEA 4HHFA 1JXCA 1LQIA 2BRZA 5BPNA 5AQSA 1B7DA 3GDQA 1P00A 1S3XA 3C7NB 3FZHA 3KHWA 5AQZA 2LJ7A 2LT8A 5F2RA 5BN8A 5AQHA 1NGEA 5CY0A 2KYQA 1JKZA 3C7NA 2LY6A 3KOWA 1T7EA 2QXLA 1KAZA 3LDLA 5AQMA 3ATVA 1BCGA 2E3GA 3PSMA 1NGHA 5AQYA 2KPYA 4AEIA 1NE5A 2E3FA 3GKUA 4H5WA 3KP1A 3KOYA 4HWIA 1BA1A 2ATBA 2LI7A 2YILA 3GL1A 2LY5A 2MZ0A 3QMLA 1SN4A 2N66A 1ATRA 3FZKA 4H5VA 5KK4A 1PTXA 3KOXA 1JZBA 1KAXA 1QQMA 4UADE 1KV0A 1CHZA 1DJTA 1VNAA 2QWNA 3LDQA 2E0HA 2I61A 2QWPA 1GPTA 1L4VA 1UGLA 2GL1A 4UAEF 2G2KA 5F1XA 1T7BA 5AQWA 5AQIA 2QWMA 1ZYWA 4H5TA 1TI5A 5AQRA 3SF4D 2NY9X 3E7UX 4H5NA 5FPEA 2GMOA 1BK8A 1C56A 1ZFUA 4FL9A 4UJ0A 1BUPA 2YC1C 3JXUA 4IO8A 1WMTA 5FPNA 2E8AA 1ZYVA 1XRSB 3AY9A 1T0ZA 3D2EB 3KP0A 2NY8X 4CQKA 3QFUA 5AQKA 2ASCA 1BRZA 1QQOA 1I2UA 1OZZA 3L56A 5AQUA 1NPIA 2KBJA 1SN1A 1ZVGA 1HJOA 3D2EA 3FE1A 2KJAA 3LDNA 1NGBA 5AQJA 3LDOA 5AQLA 5AQFA 1B3CA 2MN5A 1LQHA 1K8BA 5AQGA 1C55A 1HPMA 3E7RL 5AQVA 1NRAA 2V7ZA 2LJMA 2M8BB 5AQXA 1DQ7A 2KSKA 5FPDA 3R2VA 1NGFA 1OMYA 5AQOA 5AR0A 3A8YA 1MYNA 3D2FB 1WWNA 1HX1A 2SN3A 1ZU3A 1GPSA 2KBHA 5EX5A 1NRBA 2QWQA 1DKGD 4GNIA 1LQQA 2BUPA 5BPLA 1I6GA 2E88A 1SNBA 3D2FA 5AQQA 2JDQD
chains in the Genus database with same CATH topology
4AAZA 2N2RA 1VNBA 1AHOA 1SEGA 4V1DC 1I2VA 1AYJA 1PE4A 1MR4A 2KGQA 1BMRA 2KBKA 2B68A 2YEOA 1ZUTA 1WT7A 2B3CA 2YBRC 1JZAA 2N2QA 4HE7A 4AB0A 1I6FA 1T1TA 2LR3A 1PX9A 1CN2A 2LKBA 4KYPA 1NH5A 1FH3A 1T7AA 1P0AA 2A7TA 4HHFA 2N69A 1N4NA 1ZVEA 1JXCA 1LQIA 2BRZA 1B7DA 1P00A 2LJ7A 2LT8A 5CY0A 2KYQA 1JKZA 2LY6A 1T7EA 1BCGA 2E3GA 3PSMA 2KPYA 4AEIA 2E3FA 1NE5A 2LI7A 2ATBA 2LY5A 2MZ0A 1SN4A 2N66A 5KK4A 1PTXA 1JZBA 1KV0A 1CHZA 1DJTA 1VNAA 1L4VA 2E0HA 2I61A 1GPTA 2GL1A 1T7BA 1ZYWA 1TI5A 2NY9X 3E7UX 1BK8A 1C56A 1ZFUA 4UJ0A 2YC1C 1WMTA 1ZYVA 1T0ZA 2NY8X 4CQKA 1BRZA 2ASCA 1I2UA 1OZZA 1NPIA 2KBJA 1SN1A 1ZVGA 2KJAA 1B3CA 1LQHA 1C55A 3E7RL 1NRAA 2LJMA 2M8BB 1DQ7A 2KSKA 1OMYA 1MYNA 1WWNA 2SN3A 1ZU3A 1GPSA 2KBHA 1NRBA 1LQQA 1I6GA 1SNBA 1ICAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AAZ A;  2N2R A;  1VNB A;  1AHO A;  1SEG A;  4V1D C;  1I2V A;  1AYJ A;  1PE4 A;  1MR4 A;  2KGQ A;  1BMR A;  2KBK A;  2B68 A;  2YEO A;  1ZUT A;  1WT7 A;  2B3C A;  2YBR C;  1JZA A;  2N2Q A;  4HE7 A;  4AB0 A;  1I6F A;  1T1T A;  2LR3 A;  1PX9 A;  1CN2 A;  2LKB A;  4KYP A;  1NH5 A;  1FH3 A;  1T7A A;  1P0A A;  2A7T A;  4HHF A;  2N69 A;  1N4N A;  1ZVE A;  1JXC A;  1LQI A;  2BRZ A;  1B7D A;  1P00 A;  2LJ7 A;  2LT8 A;  5CY0 A;  2KYQ A;  1JKZ A;  2LY6 A;  1T7E A;  1BCG A;  2E3G A;  3PSM A;  2KPY A;  4AEI A;  2E3F A;  1NE5 A;  2LI7 A;  2ATB A;  2LY5 A;  2MZ0 A;  1SN4 A;  2N66 A;  5KK4 A;  1PTX A;  1JZB A;  1KV0 A;  1CHZ A;  1DJT A;  1VNA A;  1L4V A;  2E0H A;  2I61 A;  1GPT A;  2GL1 A;  1T7B A;  1ZYW A;  1TI5 A;  2NY9 X;  3E7U X;  1BK8 A;  1C56 A;  1ZFU A;  4UJ0 A;  2YC1 C;  1WMT A;  1ZYV A;  1T0Z A;  2NY8 X;  4CQK A;  1BRZ A;  2ASC A;  1I2U A;  1OZZ A;  1NPI A;  2KBJ A;  1SN1 A;  1ZVG A;  2KJA A;  1B3C A;  1LQH A;  1C55 A;  3E7R L;  1NRA A;  2LJM A;  2M8B B;  1DQ7 A;  2KSK A;  1OMY A;  1MYN A;  1WWN A;  2SN3 A;  1ZU3 A;  1GPS A;  2KBH A;  1NRB A;  1LQQ A;  1I6G A;  1SNB A;  1ICA A; 
#chains in the Genus database with same CATH topology
 3CQX A;  2N2R A;  2QW9 A;  4AAZ A;  4H5R A;  1VNB A;  1ICA A;  1AHO A;  1SEG A;  2YIO A;  3FZL A;  4V1D C;  3CW4 A;  1I2V A;  5BPM A;  3QFP A;  1AYJ A;  1PE4 A;  1MR4 A;  2KGQ A;  1BMR A;  2KBK A;  2B68 A;  2YEO A;  3M3Z A;  2D56 A;  1ZUT A;  2KHO A;  5EXW A;  1WT7 A;  1NGG A;  2B3C A;  4UAF E;  3QI7 A;  1NGD A;  5EVZ A;  2QWR A;  2YBR C;  5AQT A;  1JZA A;  1NGA A;  3L6Q A;  2N2Q A;  3FZF A;  2QWL A;  1BA0 A;  3L4I A;  1ATS A;  2LN8 A;  1YUW A;  3KC6 A;  4HE7 A;  5EY4 A;  4AB0 A;  1I6F A;  2VY6 A;  3FZM A;  1T1T A;  1NGI A;  2LR3 A;  1PX9 A;  3IUC A;  3LDP A;  3KOZ A;  5BN9 A;  1CN2 A;  1KAY A;  1POI A;  2LKB A;  4KBO A;  3HSC A;  4KYP A;  5AQN A;  2YIP A;  3BK3 C;  3I33 A;  1NH5 A;  2MBK A;  1NGC A;  2K35 A;  3ATU A;  3KVG A;  1T7A A;  1QQN A;  1P0A A;  5AQP A;  5F0X A;  1FH3 A;  2QWO A;  2A7T A;  5FPM A;  2E2F A;  4FSV A;  1NGJ A;  2N69 A;  1N4N A;  1ZVE A;  4HHF A;  1JXC A;  1LQI A;  2BRZ A;  5BPN A;  5AQS A;  1B7D A;  3GDQ A;  1P00 A;  1S3X A;  3C7N B;  3FZH A;  3KHW A;  5AQZ A;  2LJ7 A;  2LT8 A;  5F2R A;  5BN8 A;  5AQH A;  1NGE A;  5CY0 A;  2KYQ A;  1JKZ A;  3C7N A;  2LY6 A;  3KOW A;  1T7E A;  2QXL A;  1KAZ A;  3LDL A;  5AQM A;  3ATV A;  1BCG A;  2E3G A;  3PSM A;  1NGH A;  5AQY A;  2KPY A;  4AEI A;  1NE5 A;  2E3F A;  3GKU A;  4H5W A;  3KP1 A;  3KOY A;  4HWI A;  1BA1 A;  2ATB A;  2LI7 A;  2YIL A;  3GL1 A;  2LY5 A;  2MZ0 A;  3QML A;  1SN4 A;  2N66 A;  1ATR A;  3FZK A;  4H5V A;  5KK4 A;  1PTX A;  3KOX A;  1JZB A;  1KAX A;  1QQM A;  4UAD E;  1KV0 A;  1CHZ A;  1DJT A;  1VNA A;  2QWN A;  3LDQ A;  2E0H A;  2I61 A;  2QWP A;  1GPT A;  1L4V A;  1UGL A;  2GL1 A;  4UAE F;  2G2K A;  5F1X A;  1T7B A;  5AQW A;  5AQI A;  2QWM A;  1ZYW A;  4H5T A;  1TI5 A;  5AQR A;  3SF4 D;  2NY9 X;  3E7U X;  4H5N A;  5FPE A;  2GMO A;  1BK8 A;  1C56 A;  1ZFU A;  4FL9 A;  4UJ0 A;  1BUP A;  2YC1 C;  3JXU A;  4IO8 A;  1WMT A;  5FPN A;  2E8A A;  1ZYV A;  1XRS B;  3AY9 A;  1T0Z A;  3D2E B;  3KP0 A;  2NY8 X;  4CQK A;  3QFU A;  5AQK A;  2ASC A;  1BRZ A;  1QQO A;  1I2U A;  1OZZ A;  3L56 A;  5AQU A;  1NPI A;  2KBJ A;  1SN1 A;  1ZVG A;  1HJO A;  3D2E A;  3FE1 A;  2KJA A;  3LDN A;  1NGB A;  5AQJ A;  3LDO A;  5AQL A;  5AQF A;  1B3C A;  2MN5 A;  1LQH A;  1K8B A;  5AQG A;  1C55 A;  1HPM A;  3E7R L;  5AQV A;  1NRA A;  2V7Z A;  2LJM A;  2M8B B;  5AQX A;  1DQ7 A;  2KSK A;  5FPD A;  3R2V A;  1NGF A;  1OMY A;  5AQO A;  5AR0 A;  3A8Y A;  1MYN A;  3D2F B;  1WWN A;  1HX1 A;  2SN3 A;  1ZU3 A;  1GPS A;  2KBH A;  5EX5 A;  1NRB A;  2QWQ A;  1DKG D;  4GNI A;  1LQQ A;  2BUP A;  5BPL A;  1I6G A;  2E88 A;  1SNB A;  3D2F A;  5AQQ A;  2JDQ D; 
#chains in the Genus database with same CATH homology
 4AAZ A;  2N2R A;  1VNB A;  1AHO A;  1SEG A;  4V1D C;  1I2V A;  1AYJ A;  1PE4 A;  1MR4 A;  2KGQ A;  1BMR A;  2KBK A;  2B68 A;  2YEO A;  1ZUT A;  1WT7 A;  2B3C A;  2YBR C;  1JZA A;  2N2Q A;  4HE7 A;  4AB0 A;  1I6F A;  1T1T A;  2LR3 A;  1PX9 A;  1CN2 A;  2LKB A;  4KYP A;  1NH5 A;  1FH3 A;  1T7A A;  1P0A A;  2A7T A;  4HHF A;  2N69 A;  1N4N A;  1ZVE A;  1JXC A;  1LQI A;  2BRZ A;  1B7D A;  1P00 A;  2LJ7 A;  2LT8 A;  5CY0 A;  2KYQ A;  1JKZ A;  2LY6 A;  1T7E A;  1BCG A;  2E3G A;  3PSM A;  2KPY A;  4AEI A;  2E3F A;  1NE5 A;  2LI7 A;  2ATB A;  2LY5 A;  2MZ0 A;  1SN4 A;  2N66 A;  5KK4 A;  1PTX A;  1JZB A;  1KV0 A;  1CHZ A;  1DJT A;  1VNA A;  1L4V A;  2E0H A;  2I61 A;  1GPT A;  2GL1 A;  1T7B A;  1ZYW A;  1TI5 A;  2NY9 X;  3E7U X;  1BK8 A;  1C56 A;  1ZFU A;  4UJ0 A;  2YC1 C;  1WMT A;  1ZYV A;  1T0Z A;  2NY8 X;  4CQK A;  1BRZ A;  2ASC A;  1I2U A;  1OZZ A;  1NPI A;  2KBJ A;  1SN1 A;  1ZVG A;  2KJA A;  1B3C A;  1LQH A;  1C55 A;  3E7R L;  1NRA A;  2LJM A;  2M8B B;  1DQ7 A;  2KSK A;  1OMY A;  1MYN A;  1WWN A;  2SN3 A;  1ZU3 A;  1GPS A;  2KBH A;  1NRB A;  1LQQ A;  1I6G A;  1SNB A;  1ICA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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