2LI7A

Solution structure of cssii
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
66
structure length
66
Chain Sequence
KEGYLVSKSTGCKYECLKLGDNDYCLRECKQQYGKSSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Beta-mammal toxin Css2
total genus 11
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2li7A00
2LJ7A 4HHFA 2YC1C 2LY6A 1PTXA 1JZBA 1JZAA 2NY9X 1NRAA 1LQIA 1I6GA 1ZFUA 1B7DA 1ZU3A 1ZYVA 4UJ0A 1SNBA 1I2VA 1I6FA 2LI7A 1AHOA 1NRBA 2KSKA 2KYQA 5KK4A 3E7RL 2YBRC 1BCGA 1BMRA 1WMTA 1BRZA 1DQ7A 2LR3A 1MR4A 2LKBA 1T0ZA 1CHZA 1ZUTA 1VNAA 2NY8X 2N69A 1BK8A 1C56A 1MYNA 1L4VA 4CQKA 2A7TA 2B68A 1ZVEA 2LY5A 1P0AA 4HE7A 1NPIA 2N2QA 2KJAA 1JXCA 1T7AA 1GPSA 2SN3A 1ZVGA 2ATBA 1NE5A 1WWNA 2M8BB 1T7EA 1FH3A 2KBHA 1VNBA 4AEIA 1WT7A 4AAZA 2E3GA 3PSMA 2LT8A 2N2RA 1OZZA 2BRZA 1AYJA 1LQHA 2ASCA 4KYPA 1P00A 1T1TA 3E7UX 1SN1A 4V1DC 2KBJA 1NH5A 2GL1A 1T7BA 1GPTA 1SEGA 1DJTA 1PX9A 1I2UA 2KGQA 1PE4A 2E3FA 5CY0A 1LQQA 2E0HA 2YEOA 1ICAA 1ZYWA 2LJMA 2N66A 1CN2A 2I61A 1KV0A 2KPYA 1B3CA 1TI5A 1OMYA 2KBKA 1N4NA 2MZ0A 2B3CA 1SN4A 4AB0A 1JKZA 1C55A
chains in the Genus database with same CATH superfamily
5AQQA 3BK3C 2YIPA 2LJ7A 4HHFA 5FPNA 3FZMA 2YIOA 2YC1C 4H5NA 2LY6A 1KAXA 2YILA 5AQVA 2QWQA 1PTXA 1JZBA 3HSCA 3KOXA 1JZAA 2NY9X 1DKGD 1NRAA 2BUPA 3I33A 1LQIA 2E8AA 3ATUA 1NGIA 1I6GA 1ZFUA 1B7DA 1ZU3A 1ZYVA 2D56A 2QWMA 3LDLA 3QMLA 1SNBA 4UJ0A 3KOYA 2JDQD 1NGFA 4UAFE 5F2RA 1I2VA 5BN8A 1NGEA 4FSVA 5AQSA 1I6FA 1KAYA 2E2FA 3GDQA 3FE1A 3IUCA 2QWPA 5AQRA 1ATRA 2LI7A 3QFUA 3JXUA 1AHOA 1NRBA 2KSKA 4FL9A 4UADE 5AR0A 1BA0A 3C7NA 2KYQA 5KK4A 5AQTA 3E7RL 2LN8A 2YBRC 3KHWA 1BCGA 1BMRA 4UAEF 1WMTA 1UGLA 3AY9A 3KP0A 1BRZA 1BUPA 1DQ7A 2LR3A 3FZLA 1MR4A 2GMOA 1NGHA 5AQHA 2LKBA 1S3XA 1T0ZA 3LDQA 1CHZA 5AQGA 5AQZA 5FPDA 1ZUTA 1VNAA 2NY8X 2N69A 3ATVA 3FZHA 1NGJA 1BK8A 1C56A 1NGDA 5AQLA 4GNIA 5AQFA 1MYNA 5AQIA 2KHOA 1ATSA 3D2EB 2VY6A 4KBOA 5BPMA 1L4VA 4CQKA 5AQXA 5AQJA 4H5RA 3FZKA 2A7TA 2B68A 2QWLA 2QWRA 3L56A 1ZVEA 2LY5A 5AQYA 2K35A 5BN9A 1P0AA 4HE7A 3QI7A 3D2FB 1NPIA 2N2QA 2KJAA 1JXCA 3FZFA 1T7AA 3LDNA 3QFPA 1GPSA 2SN3A 5EX5A 2QWOA 1ZVGA 2ATBA 3M3ZA 4H5VA 1NE5A 1WWNA 2M8BB 1T7EA 1FH3A 1NGAA 3KC6A 1POIA 1VNBA 2KBHA 4AEIA 1WT7A 1HPMA 5AQNA 2QXLA 3A8YA 5AQOA 4AAZA 2E3GA 3GL1A 2QWNA 1NGBA 2E88A 2G2KA 5BPLA 3PSMA 2LT8A 2N2RA 1OZZA 1K8BA 2BRZA 1QQMA 1AYJA 1LQHA 5EXWA 2ASCA 3D2EA 1NGGA 1P00A 3KP1A 1T1TA 4KYPA 5AQWA 3E7UX 5FPMA 1YUWA 1SN1A 1XRSB 1QQOA 3CW4A 4V1DC 5BPNA 1HJOA 1NH5A 2KBJA 2GL1A 1BA1A 1T7BA 5AQMA 5F0XA 1GPTA 1SEGA 1DJTA 3D2FA 1PX9A 4H5WA 4IO8A 1KAZA 3L6QA 2V7ZA 1I2UA 3KOWA 2KGQA 3SF4D 2MBKA 1PE4A 5EVZA 3LDOA 3L4IA 2E3FA 5CY0A 1LQQA 2E0HA 1QQNA 2YEOA 3R2VA 1ICAA 1HX1A 3KOZA 3KVGA 5AQPA 1ZYWA 1NGCA 2LJMA 2N66A 3C7NB 4HWIA 2I61A 3CQXA 5AQUA 1CN2A 3GKUA 5FPEA 1KV0A 2KPYA 1B3CA 1TI5A 2MN5A 1OMYA 5F1XA 2KBKA 1N4NA 5AQKA 2MZ0A 2B3CA 1SN4A 5EY4A 4AB0A 4H5TA 3LDPA 2QW9A 1JKZA 1C55A
chains in the Genus database with same CATH topology
2LJ7A 4HHFA 2YC1C 2LY6A 1PTXA 1JZBA 1JZAA 2NY9X 1NRAA 1LQIA 1I6GA 1ZFUA 1B7DA 1ZU3A 1ZYVA 4UJ0A 1SNBA 1I2VA 1I6FA 2LI7A 1AHOA 1NRBA 2KSKA 2KYQA 5KK4A 3E7RL 2YBRC 1BCGA 1BMRA 1WMTA 1BRZA 1DQ7A 2LR3A 1MR4A 2LKBA 1T0ZA 1CHZA 1ZUTA 1VNAA 2NY8X 2N69A 1BK8A 1C56A 1MYNA 1L4VA 4CQKA 2A7TA 2B68A 1ZVEA 2LY5A 1P0AA 4HE7A 1NPIA 2N2QA 2KJAA 1JXCA 1T7AA 1GPSA 2SN3A 1ZVGA 2ATBA 1NE5A 1WWNA 2M8BB 1T7EA 1FH3A 2KBHA 1VNBA 4AEIA 1WT7A 4AAZA 2E3GA 3PSMA 2LT8A 2N2RA 1OZZA 2BRZA 1AYJA 1LQHA 2ASCA 4KYPA 1P00A 1T1TA 3E7UX 1SN1A 4V1DC 2KBJA 1NH5A 2GL1A 1T7BA 1GPTA 1SEGA 1DJTA 1PX9A 1I2UA 2KGQA 1PE4A 2E3FA 5CY0A 1LQQA 2E0HA 2YEOA 1ICAA 1ZYWA 2LJMA 2N66A 1CN2A 2I61A 1KV0A 2KPYA 1B3CA 1TI5A 1OMYA 2KBKA 1N4NA 2MZ0A 2B3CA 1SN4A 4AB0A 1JKZA 1C55A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LJ7 A;  4HHF A;  2YC1 C;  2LY6 A;  1PTX A;  1JZB A;  1JZA A;  2NY9 X;  1NRA A;  1LQI A;  1I6G A;  1ZFU A;  1B7D A;  1ZU3 A;  1ZYV A;  4UJ0 A;  1SNB A;  1I2V A;  1I6F A;  2LI7 A;  1AHO A;  1NRB A;  2KSK A;  2KYQ A;  5KK4 A;  3E7R L;  2YBR C;  1BCG A;  1BMR A;  1WMT A;  1BRZ A;  1DQ7 A;  2LR3 A;  1MR4 A;  2LKB A;  1T0Z A;  1CHZ A;  1ZUT A;  1VNA A;  2NY8 X;  2N69 A;  1BK8 A;  1C56 A;  1MYN A;  1L4V A;  4CQK A;  2A7T A;  2B68 A;  1ZVE A;  2LY5 A;  1P0A A;  4HE7 A;  1NPI A;  2N2Q A;  2KJA A;  1JXC A;  1T7A A;  1GPS A;  2SN3 A;  1ZVG A;  2ATB A;  1NE5 A;  1WWN A;  2M8B B;  1T7E A;  1FH3 A;  2KBH A;  1VNB A;  4AEI A;  1WT7 A;  4AAZ A;  2E3G A;  3PSM A;  2LT8 A;  2N2R A;  1OZZ A;  2BRZ A;  1AYJ A;  1LQH A;  2ASC A;  4KYP A;  1P00 A;  1T1T A;  3E7U X;  1SN1 A;  4V1D C;  2KBJ A;  1NH5 A;  2GL1 A;  1T7B A;  1GPT A;  1SEG A;  1DJT A;  1PX9 A;  1I2U A;  2KGQ A;  1PE4 A;  2E3F A;  5CY0 A;  1LQQ A;  2E0H A;  2YEO A;  1ICA A;  1ZYW A;  2LJM A;  2N66 A;  1CN2 A;  2I61 A;  1KV0 A;  2KPY A;  1B3C A;  1TI5 A;  1OMY A;  2KBK A;  1N4N A;  2MZ0 A;  2B3C A;  1SN4 A;  4AB0 A;  1JKZ A;  1C55 A; 
#chains in the Genus database with same CATH topology
 5AQQ A;  3BK3 C;  2YIP A;  2LJ7 A;  4HHF A;  5FPN A;  3FZM A;  2YIO A;  2YC1 C;  4H5N A;  2LY6 A;  1KAX A;  2YIL A;  5AQV A;  2QWQ A;  1PTX A;  1JZB A;  3HSC A;  3KOX A;  1JZA A;  2NY9 X;  1DKG D;  1NRA A;  2BUP A;  3I33 A;  1LQI A;  2E8A A;  3ATU A;  1NGI A;  1I6G A;  1ZFU A;  1B7D A;  1ZU3 A;  1ZYV A;  2D56 A;  2QWM A;  3LDL A;  3QML A;  1SNB A;  4UJ0 A;  3KOY A;  2JDQ D;  1NGF A;  4UAF E;  5F2R A;  1I2V A;  5BN8 A;  1NGE A;  4FSV A;  5AQS A;  1I6F A;  1KAY A;  2E2F A;  3GDQ A;  3FE1 A;  3IUC A;  2QWP A;  5AQR A;  1ATR A;  2LI7 A;  3QFU A;  3JXU A;  1AHO A;  1NRB A;  2KSK A;  4FL9 A;  4UAD E;  5AR0 A;  1BA0 A;  3C7N A;  2KYQ A;  5KK4 A;  5AQT A;  3E7R L;  2LN8 A;  2YBR C;  3KHW A;  1BCG A;  1BMR A;  4UAE F;  1WMT A;  1UGL A;  3AY9 A;  3KP0 A;  1BRZ A;  1BUP A;  1DQ7 A;  2LR3 A;  3FZL A;  1MR4 A;  2GMO A;  1NGH A;  5AQH A;  2LKB A;  1S3X A;  1T0Z A;  3LDQ A;  1CHZ A;  5AQG A;  5AQZ A;  5FPD A;  1ZUT A;  1VNA A;  2NY8 X;  2N69 A;  3ATV A;  3FZH A;  1NGJ A;  1BK8 A;  1C56 A;  1NGD A;  5AQL A;  4GNI A;  5AQF A;  1MYN A;  5AQI A;  2KHO A;  1ATS A;  3D2E B;  2VY6 A;  4KBO A;  5BPM A;  1L4V A;  4CQK A;  5AQX A;  5AQJ A;  4H5R A;  3FZK A;  2A7T A;  2B68 A;  2QWL A;  2QWR A;  3L56 A;  1ZVE A;  2LY5 A;  5AQY A;  2K35 A;  5BN9 A;  1P0A A;  4HE7 A;  3QI7 A;  3D2F B;  1NPI A;  2N2Q A;  2KJA A;  1JXC A;  3FZF A;  1T7A A;  3LDN A;  3QFP A;  1GPS A;  2SN3 A;  5EX5 A;  2QWO A;  1ZVG A;  2ATB A;  3M3Z A;  4H5V A;  1NE5 A;  1WWN A;  2M8B B;  1T7E A;  1FH3 A;  1NGA A;  3KC6 A;  1POI A;  1VNB A;  2KBH A;  4AEI A;  1WT7 A;  1HPM A;  5AQN A;  2QXL A;  3A8Y A;  5AQO A;  4AAZ A;  2E3G A;  3GL1 A;  2QWN A;  1NGB A;  2E88 A;  2G2K A;  5BPL A;  3PSM A;  2LT8 A;  2N2R A;  1OZZ A;  1K8B A;  2BRZ A;  1QQM A;  1AYJ A;  1LQH A;  5EXW A;  2ASC A;  3D2E A;  1NGG A;  1P00 A;  3KP1 A;  1T1T A;  4KYP A;  5AQW A;  3E7U X;  5FPM A;  1YUW A;  1SN1 A;  1XRS B;  1QQO A;  3CW4 A;  4V1D C;  5BPN A;  1HJO A;  1NH5 A;  2KBJ A;  2GL1 A;  1BA1 A;  1T7B A;  5AQM A;  5F0X A;  1GPT A;  1SEG A;  1DJT A;  3D2F A;  1PX9 A;  4H5W A;  4IO8 A;  1KAZ A;  3L6Q A;  2V7Z A;  1I2U A;  3KOW A;  2KGQ A;  3SF4 D;  2MBK A;  1PE4 A;  5EVZ A;  3LDO A;  3L4I A;  2E3F A;  5CY0 A;  1LQQ A;  2E0H A;  1QQN A;  2YEO A;  3R2V A;  1ICA A;  1HX1 A;  3KOZ A;  3KVG A;  5AQP A;  1ZYW A;  1NGC A;  2LJM A;  2N66 A;  3C7N B;  4HWI A;  2I61 A;  3CQX A;  5AQU A;  1CN2 A;  3GKU A;  5FPE A;  1KV0 A;  2KPY A;  1B3C A;  1TI5 A;  2MN5 A;  1OMY A;  5F1X A;  2KBK A;  1N4N A;  5AQK A;  2MZ0 A;  2B3C A;  1SN4 A;  5EY4 A;  4AB0 A;  4H5T A;  3LDP A;  2QW9 A;  1JKZ A;  1C55 A; 
#chains in the Genus database with same CATH homology
 2LJ7 A;  4HHF A;  2YC1 C;  2LY6 A;  1PTX A;  1JZB A;  1JZA A;  2NY9 X;  1NRA A;  1LQI A;  1I6G A;  1ZFU A;  1B7D A;  1ZU3 A;  1ZYV A;  4UJ0 A;  1SNB A;  1I2V A;  1I6F A;  2LI7 A;  1AHO A;  1NRB A;  2KSK A;  2KYQ A;  5KK4 A;  3E7R L;  2YBR C;  1BCG A;  1BMR A;  1WMT A;  1BRZ A;  1DQ7 A;  2LR3 A;  1MR4 A;  2LKB A;  1T0Z A;  1CHZ A;  1ZUT A;  1VNA A;  2NY8 X;  2N69 A;  1BK8 A;  1C56 A;  1MYN A;  1L4V A;  4CQK A;  2A7T A;  2B68 A;  1ZVE A;  2LY5 A;  1P0A A;  4HE7 A;  1NPI A;  2N2Q A;  2KJA A;  1JXC A;  1T7A A;  1GPS A;  2SN3 A;  1ZVG A;  2ATB A;  1NE5 A;  1WWN A;  2M8B B;  1T7E A;  1FH3 A;  2KBH A;  1VNB A;  4AEI A;  1WT7 A;  4AAZ A;  2E3G A;  3PSM A;  2LT8 A;  2N2R A;  1OZZ A;  2BRZ A;  1AYJ A;  1LQH A;  2ASC A;  4KYP A;  1P00 A;  1T1T A;  3E7U X;  1SN1 A;  4V1D C;  2KBJ A;  1NH5 A;  2GL1 A;  1T7B A;  1GPT A;  1SEG A;  1DJT A;  1PX9 A;  1I2U A;  2KGQ A;  1PE4 A;  2E3F A;  5CY0 A;  1LQQ A;  2E0H A;  2YEO A;  1ICA A;  1ZYW A;  2LJM A;  2N66 A;  1CN2 A;  2I61 A;  1KV0 A;  2KPY A;  1B3C A;  1TI5 A;  1OMY A;  2KBK A;  1N4N A;  2MZ0 A;  2B3C A;  1SN4 A;  4AB0 A;  1JKZ A;  1C55 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...