1NRBA

Solution structure of an old world-like neurotoxin from the venom of the new world scorpion centruroides sculpturatus ewing
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
63
structure length
63
Chain Sequence
KKDGYPVDSGNCKYECLKDDYCNDLCLERKADKGYCYWGKVSCYCYGLPDNSPTKTSGKCNPA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of an Old World-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing.
pubmed rcsb
molecule keywords NEUROTOXIN V, CSE-V
molecule tags Neurotoxin
source organism Centruroides sculpturatus
total genus 12
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 1995-01-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1nrbA00
1AYJA 1WT7A 1NRBA 1MYNA 1T1TA 2LR3A 1GPTA 1BCGA 2B68A 1I2UA 2LJMA 2A7TA 1LQQA 2YBRC 1T7BA 2N2RA 1I6GA 1B7DA 2LY5A 1NPIA 4HE7A 1WWNA 1WMTA 2MZ0A 1BMRA 1JKZA 1GPSA 1DQ7A 1JZAA 1ICAA 2KSKA 1I6FA 1OZZA 1SNBA 1C56A 1VNBA 2N2QA 2BRZA 1CHZA 1LQHA 1P00A 4V1DC 1I2VA 1PTXA 2E3GA 2KJAA 2KGQA 1MR4A 2N69A 2M8BB 1ZVEA 1TI5A 2NY8X 5CY0A 2KBHA 1NRAA 2GL1A 2LJ7A 1CN2A 2YEOA 1T0ZA 1FH3A 1ZFUA 1ZUTA 1PX9A 5KK4A 2ATBA 1ZYVA 1LQIA 2KYQA 4KYPA 2ASCA 3E7UX 2I61A 4UJ0A 1L4VA 2KBKA 3PSMA 4HHFA 1ZU3A 2E0HA 2NY9X 2E3FA 2LKBA 2KBJA 1PE4A 1P0AA 1AHOA 1VNAA 1ZYWA 2SN3A 2LI7A 4AEIA 1B3CA 1NH5A 1SN1A 2YC1C 1C55A 1NE5A 1T7AA 1ZVGA 1N4NA 1OMYA 1SN4A 1BK8A 3E7RL 4AB0A 4CQKA 2LT8A 1DJTA 2KPYA 1T7EA 2B3CA 1SEGA 2LY6A 1JXCA 1JZBA 1KV0A 4AAZA 1BRZA 2N66A
chains in the Genus database with same CATH superfamily
1AYJA 3D2EB 3LDPA 5AQGA 5FPMA 5BN8A 3KOWA 2QWMA 1WT7A 3FZLA 3QFPA 1NRBA 1MYNA 1T1TA 2QWPA 2LR3A 1GPTA 1BCGA 1BA1A 2B68A 5AQIA 5AQXA 1I2UA 2LJMA 3C7NA 3FE1A 2A7TA 1LQQA 5AQZA 3LDLA 4UADE 3I33A 3CW4A 3QMLA 1ATSA 5AQHA 5AQLA 2YBRC 5AQJA 3GL1A 1T7BA 4GNIA 2N2RA 1I6GA 1B7DA 2LY5A 1NPIA 3M3ZA 4HE7A 1NGFA 1WWNA 3JXUA 2E8AA 2GMOA 1WMTA 1UGLA 2MZ0A 4H5WA 5AQWA 1BMRA 1JKZA 5AQQA 5AQPA 4FSVA 1GPSA 1DQ7A 1JZAA 3L4IA 1ICAA 2KSKA 1KAZA 2YIPA 4FL9A 3LDOA 3L56A 1I6FA 2QWNA 2YIOA 1OZZA 1SNBA 3LDNA 1NGIA 1C56A 1VNBA 3D2FB 2LN8A 2N2QA 5BPNA 1QQNA 3KP1A 2BRZA 1CHZA 1LQHA 1QQMA 2E88A 5AQTA 1P00A 4V1DC 5AR0A 1I2VA 1PTXA 2MBKA 2E3GA 2G2KA 1KAYA 2KJAA 2KGQA 1MR4A 5AQYA 2N69A 3L6QA 2M8BB 3KOYA 1BRZA 1KAXA 3KP0A 1ZVEA 3ATVA 5AQUA 1XRSB 1TI5A 5BPMA 1NGCA 5AQMA 2NY8X 3SF4D 2KBHA 1NRAA 1QQOA 1YUWA 1BA0A 2GL1A 1NGDA 2LJ7A 2QWOA 2JDQD 2QWRA 2YEOA 1DKGD 4H5NA 5F2RA 1T0ZA 3FZMA 3LDQA 3FZFA 3KVGA 2YILA 2QWLA 4UAEF 1ATRA 1FH3A 5AQSA 4AAZA 1HPMA 3AY9A 5FPDA 1ZFUA 1ZUTA 1PX9A 3FZKA 2MN5A 5EX5A 5KK4A 2QW9A 3GDQA 2ATBA 1ZYVA 3IUCA 1LQIA 2KYQA 2E2FA 2ASCA 3E7UX 2I61A 4KYPA 1K8BA 3FZHA 5AQRA 4IO8A 4UJ0A 1NGBA 2KBKA 1L4VA 1NGAA 3PSMA 4HHFA 3C7NB 1CN2A 3KHWA 3A8YA 1ZU3A 5EXWA 1NGJA 1HJOA 3QI7A 2E0HA 2NY9X 2E3FA 2LKBA 2KBJA 1PE4A 1POIA 2V7ZA 2VY6A 1P0AA 1AHOA 2KHOA 1VNAA 3D2EA 1NGEA 3KOXA 1ZYWA 3CQXA 5FPEA 2SN3A 2LI7A 1NGHA 3GKUA 5AQKA 4AEIA 4KBOA 1NH5A 1B3CA 1BUPA 3KOZA 5FPNA 1SN1A 5BPLA 2YC1C 1C55A 1NE5A 3QFUA 1S3XA 1T7AA 3D2FA 4UAFE 1ZVGA 3ATUA 5EVZA 5BN9A 1N4NA 2D56A 1OMYA 1SN4A 1BK8A 2QXLA 3E7RL 4AB0A 5AQNA 4CQKA 5F1XA 2LT8A 3BK3C 2BUPA 4HWIA 1DJTA 4H5TA 5F0XA 2KPYA 4H5VA 5AQVA 1T7EA 5AQFA 2B3CA 1SEGA 2K35A 5CY0A 2LY6A 4H5RA 1JXCA 3KC6A 1JZBA 5EY4A 1KV0A 3HSCA 3R2VA 5AQOA 2QWQA 1HX1A 2N66A 1NGGA
chains in the Genus database with same CATH topology
1AYJA 1WT7A 1NRBA 1MYNA 1T1TA 2LR3A 1GPTA 1BCGA 2B68A 1I2UA 2LJMA 2A7TA 1LQQA 2YBRC 1T7BA 2N2RA 1I6GA 1B7DA 2LY5A 1NPIA 4HE7A 1WWNA 1WMTA 2MZ0A 1BMRA 1JKZA 1GPSA 1DQ7A 1JZAA 1ICAA 2KSKA 1I6FA 1OZZA 1SNBA 1C56A 1VNBA 2N2QA 2BRZA 1CHZA 1LQHA 1P00A 4V1DC 1I2VA 1PTXA 2E3GA 2KJAA 2KGQA 1MR4A 2N69A 2M8BB 1ZVEA 1TI5A 2NY8X 5CY0A 2KBHA 1NRAA 2GL1A 2LJ7A 1CN2A 2YEOA 1T0ZA 1FH3A 1ZFUA 1ZUTA 1PX9A 5KK4A 2ATBA 1ZYVA 1LQIA 2KYQA 4KYPA 2ASCA 3E7UX 2I61A 4UJ0A 1L4VA 2KBKA 3PSMA 4HHFA 1ZU3A 2E0HA 2NY9X 2E3FA 2LKBA 2KBJA 1PE4A 1P0AA 1AHOA 1VNAA 1ZYWA 2SN3A 2LI7A 4AEIA 1B3CA 1NH5A 1SN1A 2YC1C 1C55A 1NE5A 1T7AA 1ZVGA 1N4NA 1OMYA 1SN4A 1BK8A 3E7RL 4AB0A 4CQKA 2LT8A 1DJTA 2KPYA 1T7EA 2B3CA 1SEGA 2LY6A 1JXCA 1JZBA 1KV0A 4AAZA 1BRZA 2N66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AYJ A;  1WT7 A;  1NRB A;  1MYN A;  1T1T A;  2LR3 A;  1GPT A;  1BCG A;  2B68 A;  1I2U A;  2LJM A;  2A7T A;  1LQQ A;  2YBR C;  1T7B A;  2N2R A;  1I6G A;  1B7D A;  2LY5 A;  1NPI A;  4HE7 A;  1WWN A;  1WMT A;  2MZ0 A;  1BMR A;  1JKZ A;  1GPS A;  1DQ7 A;  1JZA A;  1ICA A;  2KSK A;  1I6F A;  1OZZ A;  1SNB A;  1C56 A;  1VNB A;  2N2Q A;  2BRZ A;  1CHZ A;  1LQH A;  1P00 A;  4V1D C;  1I2V A;  1PTX A;  2E3G A;  2KJA A;  2KGQ A;  1MR4 A;  2N69 A;  2M8B B;  1ZVE A;  1TI5 A;  2NY8 X;  5CY0 A;  2KBH A;  1NRA A;  2GL1 A;  2LJ7 A;  1CN2 A;  2YEO A;  1T0Z A;  1FH3 A;  1ZFU A;  1ZUT A;  1PX9 A;  5KK4 A;  2ATB A;  1ZYV A;  1LQI A;  2KYQ A;  4KYP A;  2ASC A;  3E7U X;  2I61 A;  4UJ0 A;  1L4V A;  2KBK A;  3PSM A;  4HHF A;  1ZU3 A;  2E0H A;  2NY9 X;  2E3F A;  2LKB A;  2KBJ A;  1PE4 A;  1P0A A;  1AHO A;  1VNA A;  1ZYW A;  2SN3 A;  2LI7 A;  4AEI A;  1B3C A;  1NH5 A;  1SN1 A;  2YC1 C;  1C55 A;  1NE5 A;  1T7A A;  1ZVG A;  1N4N A;  1OMY A;  1SN4 A;  1BK8 A;  3E7R L;  4AB0 A;  4CQK A;  2LT8 A;  1DJT A;  2KPY A;  1T7E A;  2B3C A;  1SEG A;  2LY6 A;  1JXC A;  1JZB A;  1KV0 A;  4AAZ A;  1BRZ A;  2N66 A; 
#chains in the Genus database with same CATH topology
 1AYJ A;  3D2E B;  3LDP A;  5AQG A;  5FPM A;  5BN8 A;  3KOW A;  2QWM A;  1WT7 A;  3FZL A;  3QFP A;  1NRB A;  1MYN A;  1T1T A;  2QWP A;  2LR3 A;  1GPT A;  1BCG A;  1BA1 A;  2B68 A;  5AQI A;  5AQX A;  1I2U A;  2LJM A;  3C7N A;  3FE1 A;  2A7T A;  1LQQ A;  5AQZ A;  3LDL A;  4UAD E;  3I33 A;  3CW4 A;  3QML A;  1ATS A;  5AQH A;  5AQL A;  2YBR C;  5AQJ A;  3GL1 A;  1T7B A;  4GNI A;  2N2R A;  1I6G A;  1B7D A;  2LY5 A;  1NPI A;  3M3Z A;  4HE7 A;  1NGF A;  1WWN A;  3JXU A;  2E8A A;  2GMO A;  1WMT A;  1UGL A;  2MZ0 A;  4H5W A;  5AQW A;  1BMR A;  1JKZ A;  5AQQ A;  5AQP A;  4FSV A;  1GPS A;  1DQ7 A;  1JZA A;  3L4I A;  1ICA A;  2KSK A;  1KAZ A;  2YIP A;  4FL9 A;  3LDO A;  3L56 A;  1I6F A;  2QWN A;  2YIO A;  1OZZ A;  1SNB A;  3LDN A;  1NGI A;  1C56 A;  1VNB A;  3D2F B;  2LN8 A;  2N2Q A;  5BPN A;  1QQN A;  3KP1 A;  2BRZ A;  1CHZ A;  1LQH A;  1QQM A;  2E88 A;  5AQT A;  1P00 A;  4V1D C;  5AR0 A;  1I2V A;  1PTX A;  2MBK A;  2E3G A;  2G2K A;  1KAY A;  2KJA A;  2KGQ A;  1MR4 A;  5AQY A;  2N69 A;  3L6Q A;  2M8B B;  3KOY A;  1BRZ A;  1KAX A;  3KP0 A;  1ZVE A;  3ATV A;  5AQU A;  1XRS B;  1TI5 A;  5BPM A;  1NGC A;  5AQM A;  2NY8 X;  3SF4 D;  2KBH A;  1NRA A;  1QQO A;  1YUW A;  1BA0 A;  2GL1 A;  1NGD A;  2LJ7 A;  2QWO A;  2JDQ D;  2QWR A;  2YEO A;  1DKG D;  4H5N A;  5F2R A;  1T0Z A;  3FZM A;  3LDQ A;  3FZF A;  3KVG A;  2YIL A;  2QWL A;  4UAE F;  1ATR A;  1FH3 A;  5AQS A;  4AAZ A;  1HPM A;  3AY9 A;  5FPD A;  1ZFU A;  1ZUT A;  1PX9 A;  3FZK A;  2MN5 A;  5EX5 A;  5KK4 A;  2QW9 A;  3GDQ A;  2ATB A;  1ZYV A;  3IUC A;  1LQI A;  2KYQ A;  2E2F A;  2ASC A;  3E7U X;  2I61 A;  4KYP A;  1K8B A;  3FZH A;  5AQR A;  4IO8 A;  4UJ0 A;  1NGB A;  2KBK A;  1L4V A;  1NGA A;  3PSM A;  4HHF A;  3C7N B;  1CN2 A;  3KHW A;  3A8Y A;  1ZU3 A;  5EXW A;  1NGJ A;  1HJO A;  3QI7 A;  2E0H A;  2NY9 X;  2E3F A;  2LKB A;  2KBJ A;  1PE4 A;  1POI A;  2V7Z A;  2VY6 A;  1P0A A;  1AHO A;  2KHO A;  1VNA A;  3D2E A;  1NGE A;  3KOX A;  1ZYW A;  3CQX A;  5FPE A;  2SN3 A;  2LI7 A;  1NGH A;  3GKU A;  5AQK A;  4AEI A;  4KBO A;  1NH5 A;  1B3C A;  1BUP A;  3KOZ A;  5FPN A;  1SN1 A;  5BPL A;  2YC1 C;  1C55 A;  1NE5 A;  3QFU A;  1S3X A;  1T7A A;  3D2F A;  4UAF E;  1ZVG A;  3ATU A;  5EVZ A;  5BN9 A;  1N4N A;  2D56 A;  1OMY A;  1SN4 A;  1BK8 A;  2QXL A;  3E7R L;  4AB0 A;  5AQN A;  4CQK A;  5F1X A;  2LT8 A;  3BK3 C;  2BUP A;  4HWI A;  1DJT A;  4H5T A;  5F0X A;  2KPY A;  4H5V A;  5AQV A;  1T7E A;  5AQF A;  2B3C A;  1SEG A;  2K35 A;  5CY0 A;  2LY6 A;  4H5R A;  1JXC A;  3KC6 A;  1JZB A;  5EY4 A;  1KV0 A;  3HSC A;  3R2V A;  5AQO A;  2QWQ A;  1HX1 A;  2N66 A;  1NGG A; 
#chains in the Genus database with same CATH homology
 1AYJ A;  1WT7 A;  1NRB A;  1MYN A;  1T1T A;  2LR3 A;  1GPT A;  1BCG A;  2B68 A;  1I2U A;  2LJM A;  2A7T A;  1LQQ A;  2YBR C;  1T7B A;  2N2R A;  1I6G A;  1B7D A;  2LY5 A;  1NPI A;  4HE7 A;  1WWN A;  1WMT A;  2MZ0 A;  1BMR A;  1JKZ A;  1GPS A;  1DQ7 A;  1JZA A;  1ICA A;  2KSK A;  1I6F A;  1OZZ A;  1SNB A;  1C56 A;  1VNB A;  2N2Q A;  2BRZ A;  1CHZ A;  1LQH A;  1P00 A;  4V1D C;  1I2V A;  1PTX A;  2E3G A;  2KJA A;  2KGQ A;  1MR4 A;  2N69 A;  2M8B B;  1ZVE A;  1TI5 A;  2NY8 X;  5CY0 A;  2KBH A;  1NRA A;  2GL1 A;  2LJ7 A;  1CN2 A;  2YEO A;  1T0Z A;  1FH3 A;  1ZFU A;  1ZUT A;  1PX9 A;  5KK4 A;  2ATB A;  1ZYV A;  1LQI A;  2KYQ A;  4KYP A;  2ASC A;  3E7U X;  2I61 A;  4UJ0 A;  1L4V A;  2KBK A;  3PSM A;  4HHF A;  1ZU3 A;  2E0H A;  2NY9 X;  2E3F A;  2LKB A;  2KBJ A;  1PE4 A;  1P0A A;  1AHO A;  1VNA A;  1ZYW A;  2SN3 A;  2LI7 A;  4AEI A;  1B3C A;  1NH5 A;  1SN1 A;  2YC1 C;  1C55 A;  1NE5 A;  1T7A A;  1ZVG A;  1N4N A;  1OMY A;  1SN4 A;  1BK8 A;  3E7R L;  4AB0 A;  4CQK A;  2LT8 A;  1DJT A;  2KPY A;  1T7E A;  2B3C A;  1SEG A;  2LY6 A;  1JXC A;  1JZB A;  1KV0 A;  4AAZ A;  1BRZ A;  2N66 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...