2NY9X

Nmr structure of def-abb, a mutant of anopheles defensin def-aaa
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
41
structure length
41
Chain Sequence
ATCDLASGFGVGSSLCAAHCLVKGYRGGYCKNKICHCRDKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antimicrobial protein
molecule keywords defensin, mutant DEF-ABB
publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
source organism Anopheles gambiae
total genus 6
structure length 41
sequence length 41
ec nomenclature
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ny9X00
1FH3A 1GPSA 2LJ7A 1I6FA 1SNBA 4AB0A 2KBKA 1MR4A 1I6GA 1DQ7A 2KYQA 1NPIA 2KBJA 1NRBA 2LR3A 4AAZA 1ZYVA 2N2RA 5KK4A 1P00A 1NH5A 5CY0A 3E7UX 4HHFA 1T7AA 2B3CA 1ICAA 1JZAA 1LQIA 1WT7A 1ZU3A 1L4VA 2KBHA 2YEOA 1I2UA 2YC1C 4CQKA 2LY5A 1SN1A 1PE4A 3E7RL 2A7TA 1BK8A 1B7DA 1NRAA 1VNAA 2ASCA 1MYNA 1VNBA 2B68A 1OMYA 2I61A 2KJAA 1ZVEA 1ZYWA 1N4NA 1PX9A 1DJTA 2ATBA 2SN3A 1AHOA 1T0ZA 1NE5A 1SEGA 1LQHA 1CHZA 2NY9X 1JXCA 2LI7A 1T7BA 2E3FA 1C56A 2M8BB 2MZ0A 1P0AA 1B3CA 1ZUTA 1SN4A 2N66A 2LY6A 1ZFUA 4V1DC 1LQQA 2E0HA 4AEIA 2E3GA 1JZBA 1BRZA 2NY8X 2N69A 2KGQA 3PSMA 1GPTA 2KPYA 2BRZA 4HE7A 4KYPA 1AYJA 2LKBA 1OZZA 2LT8A 2YBRC 4UJ0A 1CN2A 1C55A 1BCGA 2GL1A 1I2VA 1WMTA 1BMRA 2N2QA 2KSKA 2LJMA 1T7EA 1ZVGA 1T1TA 1PTXA 1JKZA 1KV0A 1TI5A 1WWNA
chains in the Genus database with same CATH superfamily
5AQLA 2G2KA 3ATUA 4H5VA 5FPEA 1FH3A 3GL1A 1HX1A 5EXWA 3SF4D 2LJ7A 1I6FA 5AQVA 3KOYA 1GPSA 4IO8A 3KOZA 4KBOA 1SNBA 5EY4A 4AB0A 3KP1A 1HJOA 2K35A 2KBKA 1K8BA 1MR4A 1I6GA 1DQ7A 3QFUA 2KYQA 1NPIA 2KBJA 3L56A 4GNIA 1UGLA 3FZLA 3M3ZA 1NGFA 1NRBA 2LR3A 3KVGA 5AQPA 1ZYVA 2V7ZA 2YILA 4AAZA 2N2RA 5AQQA 5AQGA 5KK4A 1P00A 1NH5A 1NGDA 5CY0A 5BN8A 3E7UX 3JXUA 2GMOA 2QWOA 4HHFA 5F1XA 3FZHA 2QWNA 1T7AA 2B3CA 5AQOA 5FPNA 1JZAA 2QWRA 1LQIA 1ICAA 1WT7A 3CQXA 3LDNA 5AQKA 3KOXA 5EX5A 1ZU3A 1L4VA 1NGCA 2KBHA 5AQRA 2YIPA 4FL9A 2YEOA 1NGJA 1I2UA 3ATVA 2QWQA 2YC1C 5AQTA 4CQKA 2VY6A 2LY5A 1NGAA 3GKUA 1HPMA 2JDQD 3AY9A 3HSCA 2BUPA 1SN1A 1PE4A 3E7RL 5AQIA 2A7TA 1BK8A 1B7DA 4H5RA 1NRAA 1VNAA 2ASCA 2E8AA 5AR0A 5F0XA 1MYNA 1VNBA 2B68A 1OMYA 2I61A 2QWLA 2KJAA 1ZVEA 1ZYWA 2QXLA 1N4NA 1PX9A 1DJTA 2ATBA 5AQUA 2SN3A 3LDQA 1QQMA 4FSVA 1AHOA 1T0ZA 1NE5A 1SEGA 1LQHA 3LDLA 1BA1A 3LDOA 4H5TA 1CHZA 2NY9X 3KC6A 3FZMA 1JXCA 3KOWA 3LDPA 1QQNA 2LI7A 5FPMA 5AQHA 1T7BA 2E3FA 1DKGD 1C56A 2M8BB 3FZFA 5EVZA 2MZ0A 1P0AA 2E2FA 2QWMA 1B3CA 1ZUTA 1KAXA 1KV0A 1NGBA 1SN4A 3FE1A 4UADE 5BPLA 1POIA 2LY6A 2N66A 3R2VA 1ZFUA 3GDQA 4V1DC 5BPMA 2QW9A 1LQQA 2E0HA 4AEIA 2E3GA 5AQFA 1NGHA 1JZBA 1BRZA 3L6QA 2NY8X 3L4IA 5AQMA 2N69A 3CW4A 5AQJA 2KGQA 2KHOA 1NGEA 3C7NA 3C7NB 1XRSB 1KAZA 3PSMA 2LN8A 1GPTA 2KPYA 2BRZA 4HE7A 4KYPA 5AQXA 5AQZA 1AYJA 3QI7A 2LKBA 1OZZA 2LT8A 1QQOA 3FZKA 2MN5A 3KP0A 1NGGA 2E88A 3KHWA 2YBRC 3QMLA 4UJ0A 3D2EA 1KAYA 1ATSA 2QWPA 3QFPA 4H5NA 3D2EB 1JKZA 2D56A 1S3XA 1YUWA 5BPNA 5AQNA 2YIOA 5BN9A 1CN2A 1C55A 5AQWA 3A8YA 3IUCA 1BCGA 2GL1A 1I2VA 1WMTA 1BMRA 4H5WA 3D2FA 2N2QA 2KSKA 3D2FB 4HWIA 2LJMA 1BUPA 3I33A 4UAEF 1T7EA 2MBKA 5AQSA 1ZVGA 4UAFE 5FPDA 1BA0A 5F2RA 1ATRA 1PTXA 1T1TA 5AQYA 1NGIA 1TI5A 1WWNA 3BK3C
chains in the Genus database with same CATH topology
1FH3A 1GPSA 2LJ7A 1I6FA 1SNBA 4AB0A 2KBKA 1MR4A 1I6GA 1DQ7A 2KYQA 1NPIA 2KBJA 1NRBA 2LR3A 4AAZA 1ZYVA 2N2RA 5KK4A 1P00A 1NH5A 5CY0A 3E7UX 4HHFA 1T7AA 2B3CA 1ICAA 1JZAA 1LQIA 1WT7A 1ZU3A 1L4VA 2KBHA 2YEOA 1I2UA 2YC1C 4CQKA 2LY5A 1SN1A 1PE4A 3E7RL 2A7TA 1BK8A 1B7DA 1NRAA 1VNAA 2ASCA 1MYNA 1VNBA 2B68A 1OMYA 2I61A 2KJAA 1ZVEA 1ZYWA 1N4NA 1PX9A 1DJTA 2ATBA 2SN3A 1AHOA 1T0ZA 1NE5A 1SEGA 1LQHA 1CHZA 2NY9X 1JXCA 2LI7A 1T7BA 2E3FA 1C56A 2M8BB 2MZ0A 1P0AA 1B3CA 1ZUTA 1SN4A 2N66A 2LY6A 1ZFUA 4V1DC 1LQQA 2E0HA 4AEIA 2E3GA 1JZBA 1BRZA 2NY8X 2N69A 2KGQA 3PSMA 1GPTA 2KPYA 2BRZA 4HE7A 4KYPA 1AYJA 2LKBA 1OZZA 2LT8A 2YBRC 4UJ0A 1CN2A 1C55A 1BCGA 2GL1A 1I2VA 1WMTA 1BMRA 2N2QA 2KSKA 2LJMA 1T7EA 1ZVGA 1T1TA 1PTXA 1JKZA 1KV0A 1TI5A 1WWNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FH3 A;  1GPS A;  2LJ7 A;  1I6F A;  1SNB A;  4AB0 A;  2KBK A;  1MR4 A;  1I6G A;  1DQ7 A;  2KYQ A;  1NPI A;  2KBJ A;  1NRB A;  2LR3 A;  4AAZ A;  1ZYV A;  2N2R A;  5KK4 A;  1P00 A;  1NH5 A;  5CY0 A;  3E7U X;  4HHF A;  1T7A A;  2B3C A;  1ICA A;  1JZA A;  1LQI A;  1WT7 A;  1ZU3 A;  1L4V A;  2KBH A;  2YEO A;  1I2U A;  2YC1 C;  4CQK A;  2LY5 A;  1SN1 A;  1PE4 A;  3E7R L;  2A7T A;  1BK8 A;  1B7D A;  1NRA A;  1VNA A;  2ASC A;  1MYN A;  1VNB A;  2B68 A;  1OMY A;  2I61 A;  2KJA A;  1ZVE A;  1ZYW A;  1N4N A;  1PX9 A;  1DJT A;  2ATB A;  2SN3 A;  1AHO A;  1T0Z A;  1NE5 A;  1SEG A;  1LQH A;  1CHZ A;  2NY9 X;  1JXC A;  2LI7 A;  1T7B A;  2E3F A;  1C56 A;  2M8B B;  2MZ0 A;  1P0A A;  1B3C A;  1ZUT A;  1SN4 A;  2N66 A;  2LY6 A;  1ZFU A;  4V1D C;  1LQQ A;  2E0H A;  4AEI A;  2E3G A;  1JZB A;  1BRZ A;  2NY8 X;  2N69 A;  2KGQ A;  3PSM A;  1GPT A;  2KPY A;  2BRZ A;  4HE7 A;  4KYP A;  1AYJ A;  2LKB A;  1OZZ A;  2LT8 A;  2YBR C;  4UJ0 A;  1CN2 A;  1C55 A;  1BCG A;  2GL1 A;  1I2V A;  1WMT A;  1BMR A;  2N2Q A;  2KSK A;  2LJM A;  1T7E A;  1ZVG A;  1T1T A;  1PTX A;  1JKZ A;  1KV0 A;  1TI5 A;  1WWN A; 
#chains in the Genus database with same CATH topology
 5AQL A;  2G2K A;  3ATU A;  4H5V A;  5FPE A;  1FH3 A;  3GL1 A;  1HX1 A;  5EXW A;  3SF4 D;  2LJ7 A;  1I6F A;  5AQV A;  3KOY A;  1GPS A;  4IO8 A;  3KOZ A;  4KBO A;  1SNB A;  5EY4 A;  4AB0 A;  3KP1 A;  1HJO A;  2K35 A;  2KBK A;  1K8B A;  1MR4 A;  1I6G A;  1DQ7 A;  3QFU A;  2KYQ A;  1NPI A;  2KBJ A;  3L56 A;  4GNI A;  1UGL A;  3FZL A;  3M3Z A;  1NGF A;  1NRB A;  2LR3 A;  3KVG A;  5AQP A;  1ZYV A;  2V7Z A;  2YIL A;  4AAZ A;  2N2R A;  5AQQ A;  5AQG A;  5KK4 A;  1P00 A;  1NH5 A;  1NGD A;  5CY0 A;  5BN8 A;  3E7U X;  3JXU A;  2GMO A;  2QWO A;  4HHF A;  5F1X A;  3FZH A;  2QWN A;  1T7A A;  2B3C A;  5AQO A;  5FPN A;  1JZA A;  2QWR A;  1LQI A;  1ICA A;  1WT7 A;  3CQX A;  3LDN A;  5AQK A;  3KOX A;  5EX5 A;  1ZU3 A;  1L4V A;  1NGC A;  2KBH A;  5AQR A;  2YIP A;  4FL9 A;  2YEO A;  1NGJ A;  1I2U A;  3ATV A;  2QWQ A;  2YC1 C;  5AQT A;  4CQK A;  2VY6 A;  2LY5 A;  1NGA A;  3GKU A;  1HPM A;  2JDQ D;  3AY9 A;  3HSC A;  2BUP A;  1SN1 A;  1PE4 A;  3E7R L;  5AQI A;  2A7T A;  1BK8 A;  1B7D A;  4H5R A;  1NRA A;  1VNA A;  2ASC A;  2E8A A;  5AR0 A;  5F0X A;  1MYN A;  1VNB A;  2B68 A;  1OMY A;  2I61 A;  2QWL A;  2KJA A;  1ZVE A;  1ZYW A;  2QXL A;  1N4N A;  1PX9 A;  1DJT A;  2ATB A;  5AQU A;  2SN3 A;  3LDQ A;  1QQM A;  4FSV A;  1AHO A;  1T0Z A;  1NE5 A;  1SEG A;  1LQH A;  3LDL A;  1BA1 A;  3LDO A;  4H5T A;  1CHZ A;  2NY9 X;  3KC6 A;  3FZM A;  1JXC A;  3KOW A;  3LDP A;  1QQN A;  2LI7 A;  5FPM A;  5AQH A;  1T7B A;  2E3F A;  1DKG D;  1C56 A;  2M8B B;  3FZF A;  5EVZ A;  2MZ0 A;  1P0A A;  2E2F A;  2QWM A;  1B3C A;  1ZUT A;  1KAX A;  1KV0 A;  1NGB A;  1SN4 A;  3FE1 A;  4UAD E;  5BPL A;  1POI A;  2LY6 A;  2N66 A;  3R2V A;  1ZFU A;  3GDQ A;  4V1D C;  5BPM A;  2QW9 A;  1LQQ A;  2E0H A;  4AEI A;  2E3G A;  5AQF A;  1NGH A;  1JZB A;  1BRZ A;  3L6Q A;  2NY8 X;  3L4I A;  5AQM A;  2N69 A;  3CW4 A;  5AQJ A;  2KGQ A;  2KHO A;  1NGE A;  3C7N A;  3C7N B;  1XRS B;  1KAZ A;  3PSM A;  2LN8 A;  1GPT A;  2KPY A;  2BRZ A;  4HE7 A;  4KYP A;  5AQX A;  5AQZ A;  1AYJ A;  3QI7 A;  2LKB A;  1OZZ A;  2LT8 A;  1QQO A;  3FZK A;  2MN5 A;  3KP0 A;  1NGG A;  2E88 A;  3KHW A;  2YBR C;  3QML A;  4UJ0 A;  3D2E A;  1KAY A;  1ATS A;  2QWP A;  3QFP A;  4H5N A;  3D2E B;  1JKZ A;  2D56 A;  1S3X A;  1YUW A;  5BPN A;  5AQN A;  2YIO A;  5BN9 A;  1CN2 A;  1C55 A;  5AQW A;  3A8Y A;  3IUC A;  1BCG A;  2GL1 A;  1I2V A;  1WMT A;  1BMR A;  4H5W A;  3D2F A;  2N2Q A;  2KSK A;  3D2F B;  4HWI A;  2LJM A;  1BUP A;  3I33 A;  4UAE F;  1T7E A;  2MBK A;  5AQS A;  1ZVG A;  4UAF E;  5FPD A;  1BA0 A;  5F2R A;  1ATR A;  1PTX A;  1T1T A;  5AQY A;  1NGI A;  1TI5 A;  1WWN A;  3BK3 C; 
#chains in the Genus database with same CATH homology
 1FH3 A;  1GPS A;  2LJ7 A;  1I6F A;  1SNB A;  4AB0 A;  2KBK A;  1MR4 A;  1I6G A;  1DQ7 A;  2KYQ A;  1NPI A;  2KBJ A;  1NRB A;  2LR3 A;  4AAZ A;  1ZYV A;  2N2R A;  5KK4 A;  1P00 A;  1NH5 A;  5CY0 A;  3E7U X;  4HHF A;  1T7A A;  2B3C A;  1ICA A;  1JZA A;  1LQI A;  1WT7 A;  1ZU3 A;  1L4V A;  2KBH A;  2YEO A;  1I2U A;  2YC1 C;  4CQK A;  2LY5 A;  1SN1 A;  1PE4 A;  3E7R L;  2A7T A;  1BK8 A;  1B7D A;  1NRA A;  1VNA A;  2ASC A;  1MYN A;  1VNB A;  2B68 A;  1OMY A;  2I61 A;  2KJA A;  1ZVE A;  1ZYW A;  1N4N A;  1PX9 A;  1DJT A;  2ATB A;  2SN3 A;  1AHO A;  1T0Z A;  1NE5 A;  1SEG A;  1LQH A;  1CHZ A;  2NY9 X;  1JXC A;  2LI7 A;  1T7B A;  2E3F A;  1C56 A;  2M8B B;  2MZ0 A;  1P0A A;  1B3C A;  1ZUT A;  1SN4 A;  2N66 A;  2LY6 A;  1ZFU A;  4V1D C;  1LQQ A;  2E0H A;  4AEI A;  2E3G A;  1JZB A;  1BRZ A;  2NY8 X;  2N69 A;  2KGQ A;  3PSM A;  1GPT A;  2KPY A;  2BRZ A;  4HE7 A;  4KYP A;  1AYJ A;  2LKB A;  1OZZ A;  2LT8 A;  2YBR C;  4UJ0 A;  1CN2 A;  1C55 A;  1BCG A;  2GL1 A;  1I2V A;  1WMT A;  1BMR A;  2N2Q A;  2KSK A;  2LJM A;  1T7E A;  1ZVG A;  1T1T A;  1PTX A;  1JKZ A;  1KV0 A;  1TI5 A;  1WWN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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