1I2VA

Nmr solution structures of an antifungal and antibacterial mutant of heliomicin
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSDCNGECLLRGYKGGHCGSFANVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
pubmed doi rcsb
molecule keywords DEFENSIN HELIOMICIN
molecule tags Antimicrobial protein
source organism Heliothis virescens
total genus 8
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2001-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1i2vA00
1LQQA 2B68A 4KYPA 1ZVGA 5KK4A 1OZZA 1JKZA 2E0HA 2LT8A 1T7EA 1NRAA 1VNAA 1ZYWA 4UJ0A 1FH3A 1CN2A 1VNBA 1GPSA 2KPYA 2E3GA 2I61A 1JXCA 4V1DC 2B3CA 2MZ0A 1SEGA 4HE7A 1I6GA 1NPIA 4AB0A 2KSKA 2E3FA 2LJ7A 1T7AA 1PX9A 1B7DA 1KV0A 1BK8A 1DQ7A 2M8BB 1SN1A 2N69A 1BCGA 2ATBA 2KJAA 2A7TA 1I6FA 4AAZA 2KBHA 1T1TA 4AEIA 1PE4A 1WMTA 2NY8X 1I2UA 1B3CA 1NE5A 1NH5A 1I2VA 2KGQA 2NY9X 1PTXA 1TI5A 1P0AA 2N2RA 2LY5A 2GL1A 1BRZA 1LQIA 1JZAA 2KYQA 2YC1C 1ICAA 2N2QA 1ZU3A 1ZVEA 2BRZA 2LJMA 1C56A 3PSMA 3E7RL 2ASCA 2LKBA 1T0ZA 1C55A 1DJTA 1MR4A 1SN4A 1L4VA 2YBRC 2KBJA 1BMRA 1SNBA 1T7BA 1NRBA 1OMYA 1AYJA 2N66A 2LY6A 1CHZA 2KBKA 5CY0A 1WT7A 1GPTA 4HHFA 2LR3A 1ZYVA 1ZUTA 1AHOA 2YEOA 1P00A 3E7UX 1N4NA 2SN3A 1LQHA 1JZBA 1WWNA 1MYNA 4CQKA 1ZFUA 2LI7A
chains in the Genus database with same CATH superfamily
2QW9A 1LQQA 5AQKA 4HWIA 2B68A 5EXWA 3LDQA 5BPLA 2KHOA 3LDOA 1NGEA 4KYPA 2K35A 5AQIA 1NGAA 1ZVGA 5AQUA 5BPNA 5KK4A 3D2EA 1HJOA 1NGFA 1OZZA 1JKZA 5FPMA 1DKGD 4UADE 3C7NA 3KP1A 3QI7A 1YUWA 1POIA 1T7EA 1NRAA 1VNAA 1NGJA 1QQMA 1KAYA 1ZYWA 2E0HA 2LT8A 3FZKA 3QFUA 1FH3A 1CN2A 1VNBA 1GPSA 3KC6A 3KOXA 5AQZA 2KPYA 2QWQA 2E3GA 2I61A 3BK3C 1JXCA 3GL1A 4UAFE 4V1DC 3IUCA 5FPNA 2B3CA 3QMLA 2MZ0A 1SEGA 1NGCA 4HE7A 3FZLA 2JDQD 3L4IA 5BPMA 1I6GA 1K8BA 3AY9A 1NPIA 2MN5A 4AB0A 4UJ0A 2KSKA 2E3FA 2LJ7A 1T7AA 3LDNA 1PX9A 1B7DA 1KV0A 3KOWA 5AQFA 3KHWA 1BK8A 1DQ7A 2QWOA 2YIOA 2M8BB 4H5VA 5AQWA 1SN1A 2N69A 3KOYA 3D2FB 4FL9A 4GNIA 3FZHA 5AQTA 1BCGA 2E8AA 1QQOA 2ATBA 5F2RA 2KJAA 5AQVA 1HX1A 1NGIA 2A7TA 3L6QA 1I6FA 3KOZA 3SF4D 2KBHA 2MBKA 5AQOA 4AAZA 4H5TA 1T1TA 3FE1A 1PE4A 1WMTA 2NY8X 3GDQA 4AEIA 1B3CA 1I2UA 2YILA 5AQHA 3LDPA 2QWLA 1BA1A 5AQLA 5AR0A 1NE5A 1NH5A 1I2VA 3FZMA 2LN8A 2KGQA 2NY9X 1BUPA 1PTXA 1TI5A 1P0AA 2N2RA 2LY5A 1ATRA 2GL1A 3ATVA 3QFPA 5F0XA 1BRZA 1LQIA 1JZAA 2E2FA 2KYQA 4H5RA 1ATSA 2QWPA 1KAZA 2YC1C 2D56A 4IO8A 2BUPA 2QWNA 1ICAA 1BA0A 2YIPA 5FPDA 2N2QA 1ZU3A 1ZVEA 2BRZA 2LJMA 1C56A 1HPMA 2VY6A 3PSMA 4H5NA 5EX5A 3E7RL 3R2VA 1NGHA 1NGBA 5AQNA 5F1XA 2QWRA 2ASCA 2LKBA 3LDLA 5FPEA 1KAXA 1T0ZA 1DJTA 1C55A 1MR4A 1SN4A 1L4VA 2YBRC 2KBJA 1BMRA 1SNBA 5BN8A 2G2KA 1XRSB 1T7BA 3D2FA 1NRBA 3CW4A 1OMYA 2E88A 2QXLA 5AQSA 1AYJA 2N66A 5EY4A 2LY6A 4UAEF 1CHZA 2KBKA 2QWMA 5AQPA 3D2EB 5CY0A 1QQNA 5EVZA 1WT7A 3A8YA 1GPTA 3ATUA 3C7NB 4H5WA 4HHFA 5AQXA 3GKUA 2LR3A 5AQQA 5AQYA 5BN9A 1ZYVA 1ZUTA 1UGLA 3FZFA 1NGDA 1AHOA 2YEOA 4FSVA 3HSCA 1P00A 3L56A 5AQGA 2GMOA 3M3ZA 1NGGA 3E7UX 1N4NA 2SN3A 1LQHA 3KVGA 1JZBA 1WWNA 1S3XA 5AQMA 3JXUA 1MYNA 3KP0A 3CQXA 5AQJA 4CQKA 1ZFUA 5AQRA 3I33A 4KBOA 2V7ZA 2LI7A
chains in the Genus database with same CATH topology
1LQQA 2B68A 4KYPA 1ZVGA 5KK4A 1OZZA 1JKZA 2E0HA 2LT8A 1T7EA 1NRAA 1VNAA 1ZYWA 4UJ0A 1FH3A 1CN2A 1VNBA 1GPSA 2KPYA 2E3GA 2I61A 1JXCA 4V1DC 2B3CA 2MZ0A 1SEGA 4HE7A 1I6GA 1NPIA 4AB0A 2KSKA 2E3FA 2LJ7A 1T7AA 1PX9A 1B7DA 1KV0A 1BK8A 1DQ7A 2M8BB 1SN1A 2N69A 1BCGA 2ATBA 2KJAA 2A7TA 1I6FA 4AAZA 2KBHA 1T1TA 4AEIA 1PE4A 1WMTA 2NY8X 1I2UA 1B3CA 1NE5A 1NH5A 1I2VA 2KGQA 2NY9X 1PTXA 1TI5A 1P0AA 2N2RA 2LY5A 2GL1A 1BRZA 1LQIA 1JZAA 2KYQA 2YC1C 1ICAA 2N2QA 1ZU3A 1ZVEA 2BRZA 2LJMA 1C56A 3PSMA 3E7RL 2ASCA 2LKBA 1T0ZA 1C55A 1DJTA 1MR4A 1SN4A 1L4VA 2YBRC 2KBJA 1BMRA 1SNBA 1T7BA 1NRBA 1OMYA 1AYJA 2N66A 2LY6A 1CHZA 2KBKA 5CY0A 1WT7A 1GPTA 4HHFA 2LR3A 1ZYVA 1ZUTA 1AHOA 2YEOA 1P00A 3E7UX 1N4NA 2SN3A 1LQHA 1JZBA 1WWNA 1MYNA 4CQKA 1ZFUA 2LI7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LQQ A;  2B68 A;  4KYP A;  1ZVG A;  5KK4 A;  1OZZ A;  1JKZ A;  2E0H A;  2LT8 A;  1T7E A;  1NRA A;  1VNA A;  1ZYW A;  4UJ0 A;  1FH3 A;  1CN2 A;  1VNB A;  1GPS A;  2KPY A;  2E3G A;  2I61 A;  1JXC A;  4V1D C;  2B3C A;  2MZ0 A;  1SEG A;  4HE7 A;  1I6G A;  1NPI A;  4AB0 A;  2KSK A;  2E3F A;  2LJ7 A;  1T7A A;  1PX9 A;  1B7D A;  1KV0 A;  1BK8 A;  1DQ7 A;  2M8B B;  1SN1 A;  2N69 A;  1BCG A;  2ATB A;  2KJA A;  2A7T A;  1I6F A;  4AAZ A;  2KBH A;  1T1T A;  4AEI A;  1PE4 A;  1WMT A;  2NY8 X;  1I2U A;  1B3C A;  1NE5 A;  1NH5 A;  1I2V A;  2KGQ A;  2NY9 X;  1PTX A;  1TI5 A;  1P0A A;  2N2R A;  2LY5 A;  2GL1 A;  1BRZ A;  1LQI A;  1JZA A;  2KYQ A;  2YC1 C;  1ICA A;  2N2Q A;  1ZU3 A;  1ZVE A;  2BRZ A;  2LJM A;  1C56 A;  3PSM A;  3E7R L;  2ASC A;  2LKB A;  1T0Z A;  1C55 A;  1DJT A;  1MR4 A;  1SN4 A;  1L4V A;  2YBR C;  2KBJ A;  1BMR A;  1SNB A;  1T7B A;  1NRB A;  1OMY A;  1AYJ A;  2N66 A;  2LY6 A;  1CHZ A;  2KBK A;  5CY0 A;  1WT7 A;  1GPT A;  4HHF A;  2LR3 A;  1ZYV A;  1ZUT A;  1AHO A;  2YEO A;  1P00 A;  3E7U X;  1N4N A;  2SN3 A;  1LQH A;  1JZB A;  1WWN A;  1MYN A;  4CQK A;  1ZFU A;  2LI7 A; 
#chains in the Genus database with same CATH topology
 2QW9 A;  1LQQ A;  5AQK A;  4HWI A;  2B68 A;  5EXW A;  3LDQ A;  5BPL A;  2KHO A;  3LDO A;  1NGE A;  4KYP A;  2K35 A;  5AQI A;  1NGA A;  1ZVG A;  5AQU A;  5BPN A;  5KK4 A;  3D2E A;  1HJO A;  1NGF A;  1OZZ A;  1JKZ A;  5FPM A;  1DKG D;  4UAD E;  3C7N A;  3KP1 A;  3QI7 A;  1YUW A;  1POI A;  1T7E A;  1NRA A;  1VNA A;  1NGJ A;  1QQM A;  1KAY A;  1ZYW A;  2E0H A;  2LT8 A;  3FZK A;  3QFU A;  1FH3 A;  1CN2 A;  1VNB A;  1GPS A;  3KC6 A;  3KOX A;  5AQZ A;  2KPY A;  2QWQ A;  2E3G A;  2I61 A;  3BK3 C;  1JXC A;  3GL1 A;  4UAF E;  4V1D C;  3IUC A;  5FPN A;  2B3C A;  3QML A;  2MZ0 A;  1SEG A;  1NGC A;  4HE7 A;  3FZL A;  2JDQ D;  3L4I A;  5BPM A;  1I6G A;  1K8B A;  3AY9 A;  1NPI A;  2MN5 A;  4AB0 A;  4UJ0 A;  2KSK A;  2E3F A;  2LJ7 A;  1T7A A;  3LDN A;  1PX9 A;  1B7D A;  1KV0 A;  3KOW A;  5AQF A;  3KHW A;  1BK8 A;  1DQ7 A;  2QWO A;  2YIO A;  2M8B B;  4H5V A;  5AQW A;  1SN1 A;  2N69 A;  3KOY A;  3D2F B;  4FL9 A;  4GNI A;  3FZH A;  5AQT A;  1BCG A;  2E8A A;  1QQO A;  2ATB A;  5F2R A;  2KJA A;  5AQV A;  1HX1 A;  1NGI A;  2A7T A;  3L6Q A;  1I6F A;  3KOZ A;  3SF4 D;  2KBH A;  2MBK A;  5AQO A;  4AAZ A;  4H5T A;  1T1T A;  3FE1 A;  1PE4 A;  1WMT A;  2NY8 X;  3GDQ A;  4AEI A;  1B3C A;  1I2U A;  2YIL A;  5AQH A;  3LDP A;  2QWL A;  1BA1 A;  5AQL A;  5AR0 A;  1NE5 A;  1NH5 A;  1I2V A;  3FZM A;  2LN8 A;  2KGQ A;  2NY9 X;  1BUP A;  1PTX A;  1TI5 A;  1P0A A;  2N2R A;  2LY5 A;  1ATR A;  2GL1 A;  3ATV A;  3QFP A;  5F0X A;  1BRZ A;  1LQI A;  1JZA A;  2E2F A;  2KYQ A;  4H5R A;  1ATS A;  2QWP A;  1KAZ A;  2YC1 C;  2D56 A;  4IO8 A;  2BUP A;  2QWN A;  1ICA A;  1BA0 A;  2YIP A;  5FPD A;  2N2Q A;  1ZU3 A;  1ZVE A;  2BRZ A;  2LJM A;  1C56 A;  1HPM A;  2VY6 A;  3PSM A;  4H5N A;  5EX5 A;  3E7R L;  3R2V A;  1NGH A;  1NGB A;  5AQN A;  5F1X A;  2QWR A;  2ASC A;  2LKB A;  3LDL A;  5FPE A;  1KAX A;  1T0Z A;  1DJT A;  1C55 A;  1MR4 A;  1SN4 A;  1L4V A;  2YBR C;  2KBJ A;  1BMR A;  1SNB A;  5BN8 A;  2G2K A;  1XRS B;  1T7B A;  3D2F A;  1NRB A;  3CW4 A;  1OMY A;  2E88 A;  2QXL A;  5AQS A;  1AYJ A;  2N66 A;  5EY4 A;  2LY6 A;  4UAE F;  1CHZ A;  2KBK A;  2QWM A;  5AQP A;  3D2E B;  5CY0 A;  1QQN A;  5EVZ A;  1WT7 A;  3A8Y A;  1GPT A;  3ATU A;  3C7N B;  4H5W A;  4HHF A;  5AQX A;  3GKU A;  2LR3 A;  5AQQ A;  5AQY A;  5BN9 A;  1ZYV A;  1ZUT A;  1UGL A;  3FZF A;  1NGD A;  1AHO A;  2YEO A;  4FSV A;  3HSC A;  1P00 A;  3L56 A;  5AQG A;  2GMO A;  3M3Z A;  1NGG A;  3E7U X;  1N4N A;  2SN3 A;  1LQH A;  3KVG A;  1JZB A;  1WWN A;  1S3X A;  5AQM A;  3JXU A;  1MYN A;  3KP0 A;  3CQX A;  5AQJ A;  4CQK A;  1ZFU A;  5AQR A;  3I33 A;  4KBO A;  2V7Z A;  2LI7 A; 
#chains in the Genus database with same CATH homology
 1LQQ A;  2B68 A;  4KYP A;  1ZVG A;  5KK4 A;  1OZZ A;  1JKZ A;  2E0H A;  2LT8 A;  1T7E A;  1NRA A;  1VNA A;  1ZYW A;  4UJ0 A;  1FH3 A;  1CN2 A;  1VNB A;  1GPS A;  2KPY A;  2E3G A;  2I61 A;  1JXC A;  4V1D C;  2B3C A;  2MZ0 A;  1SEG A;  4HE7 A;  1I6G A;  1NPI A;  4AB0 A;  2KSK A;  2E3F A;  2LJ7 A;  1T7A A;  1PX9 A;  1B7D A;  1KV0 A;  1BK8 A;  1DQ7 A;  2M8B B;  1SN1 A;  2N69 A;  1BCG A;  2ATB A;  2KJA A;  2A7T A;  1I6F A;  4AAZ A;  2KBH A;  1T1T A;  4AEI A;  1PE4 A;  1WMT A;  2NY8 X;  1I2U A;  1B3C A;  1NE5 A;  1NH5 A;  1I2V A;  2KGQ A;  2NY9 X;  1PTX A;  1TI5 A;  1P0A A;  2N2R A;  2LY5 A;  2GL1 A;  1BRZ A;  1LQI A;  1JZA A;  2KYQ A;  2YC1 C;  1ICA A;  2N2Q A;  1ZU3 A;  1ZVE A;  2BRZ A;  2LJM A;  1C56 A;  3PSM A;  3E7R L;  2ASC A;  2LKB A;  1T0Z A;  1C55 A;  1DJT A;  1MR4 A;  1SN4 A;  1L4V A;  2YBR C;  2KBJ A;  1BMR A;  1SNB A;  1T7B A;  1NRB A;  1OMY A;  1AYJ A;  2N66 A;  2LY6 A;  1CHZ A;  2KBK A;  5CY0 A;  1WT7 A;  1GPT A;  4HHF A;  2LR3 A;  1ZYV A;  1ZUT A;  1AHO A;  2YEO A;  1P00 A;  3E7U X;  1N4N A;  2SN3 A;  1LQH A;  1JZB A;  1WWN A;  1MYN A;  4CQK A;  1ZFU A;  2LI7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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