2ASCA

Scorpion toxin lqh-alpha-it
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
65
structure length
65
Chain Sequence
MVRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVPGKCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
rcsb
molecule tags Toxin
source organism Leiurus quinquestriatus
molecule keywords neurotoxin alpha-IT
total genus 15
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2005-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ascA00
2LR3A 4HE7A 1ICAA 1JXCA 1T7EA 1SN4A 2GL1A 1JKZA 1BRZA 1VNAA 5KK4A 1N4NA 1T7AA 4AEIA 2E3FA 1I6FA 1FH3A 1VNBA 1DJTA 2A7TA 1P0AA 2ATBA 4AAZA 1I2VA 1LQIA 2LY6A 2KPYA 1AHOA 2LJMA 2LT8A 1ZYVA 4KYPA 1MR4A 1BMRA 1B7DA 1ZUTA 2B68A 1BCGA 2I61A 1GPTA 2YEOA 1DQ7A 2YC1C 1ZU3A 4CQKA 1P00A 1AYJA 1TI5A 1SNBA 2E3GA 1I2UA 1OZZA 2LJ7A 1ZFUA 1OMYA 1MYNA 1WT7A 5CY0A 1BK8A 1T7BA 1C55A 1NRAA 2KYQA 1PE4A 1WMTA 2KBHA 2N2QA 2KJAA 1GPSA 1CHZA 1I6GA 2BRZA 2LI7A 1NH5A 3E7RL 3PSMA 1NE5A 4AB0A 2SN3A 1SN1A 1WWNA 1LQHA 1T1TA 2N2RA 1LQQA 1ZYWA 1CN2A 2KGQA 2KBJA 2ASCA 2NY9X 2B3CA 1B3CA 2KBKA 1ZVGA 2E0HA 1T0ZA 2N69A 1KV0A 1NPIA 4V1DC 2YBRC 4UJ0A 1SEGA 2MZ0A 2KSKA 4HHFA 1C56A 1NRBA 2LY5A 2NY8X 3E7UX 1ZVEA 1JZAA 2M8BB 2LKBA 1L4VA 2N66A 1PX9A 1PTXA 1JZBA
chains in the Genus database with same CATH superfamily
2LR3A 4HE7A 1ICAA 1JXCA 1T7EA 4KBOA 1SN4A 2GL1A 2E8AA 5AR0A 1JKZA 1QQNA 3BK3C 5AQMA 1K8BA 3L6QA 1HX1A 5AQTA 1BRZA 5FPDA 1POIA 1VNAA 5KK4A 1N4NA 3C7NB 3HSCA 1T7AA 3LDPA 3QFPA 2E3FA 4AEIA 1QQMA 1I6FA 1FH3A 2GMOA 3KC6A 1VNBA 5EY4A 3QFUA 3D2FB 1DJTA 2A7TA 1P0AA 2ATBA 4AAZA 1I2VA 5EXWA 1LQIA 4H5VA 5AQHA 2QWPA 2LY6A 3ATUA 3AY9A 1ATSA 2QXLA 3GKUA 3KOXA 5AQFA 2KHOA 1DKGD 5AQNA 1BA0A 1NGDA 4H5WA 2KPYA 1AHOA 2LJMA 3QMLA 2QW9A 2QWNA 2LT8A 1ZYVA 2E2FA 2QWRA 4KYPA 2BUPA 1MR4A 1YUWA 2QWOA 5AQZA 1BMRA 5AQRA 3SF4D 1B7DA 1ZUTA 3FZKA 3KP0A 2LN8A 5EVZA 1NGEA 2B68A 1BCGA 3C7NA 2I61A 4FSVA 2D56A 5AQYA 1GPTA 5AQJA 3FZHA 2YEOA 4IO8A 2JDQD 1DQ7A 3FE1A 5AQLA 1UGLA 2VY6A 5FPNA 5BPNA 3D2FA 2YC1C 1ZU3A 3JXUA 3LDLA 4UAEF 3I33A 1P00A 4GNIA 4CQKA 1TI5A 1BUPA 1SNBA 2E3GA 1AYJA 1I2UA 1OZZA 5BN9A 2LJ7A 3LDOA 5EX5A 1ZFUA 1OMYA 4H5RA 2QWQA 5AQOA 5AQSA 1MYNA 1WT7A 5BPLA 5CY0A 1BK8A 2MBKA 1T7BA 1C55A 1NRAA 2KYQA 3D2EB 4UADE 2QWLA 5AQWA 1PE4A 3KOZA 5BPMA 1QQOA 1NGHA 1WMTA 2KBHA 2N2QA 2KJAA 2V7ZA 1GPSA 1CHZA 1I6GA 2BRZA 2LI7A 3R2VA 1NH5A 3E7RL 1BA1A 3PSMA 1NGCA 1NGAA 1HJOA 1KAXA 1NE5A 5BN8A 5F0XA 5AQPA 4AB0A 2SN3A 2E88A 2YIOA 3CQXA 4H5TA 1KAYA 2MN5A 1SN1A 5F1XA 1WWNA 1LQHA 1T1TA 3L4IA 2QWMA 2N2RA 5AQIA 5AQGA 1LQQA 3GL1A 3L56A 1ZYWA 3LDNA 1JZBA 3GDQA 3KP1A 2KGQA 1CN2A 2ASCA 2KBJA 2NY9X 1XRSB 2B3CA 1B3CA 4FL9A 2KBKA 1ZVGA 5AQKA 2E0HA 1T0ZA 2G2KA 4UAFE 1NGJA 4HWIA 5AQVA 3KVGA 2N69A 1KV0A 1NPIA 3IUCA 3FZLA 3QI7A 4H5NA 3D2EA 1KAZA 1NGGA 2YBRC 2YIPA 4V1DC 4UJ0A 3FZFA 1HPMA 1SEGA 2MZ0A 2KSKA 4HHFA 5AQXA 1C56A 1S3XA 5FPEA 3CW4A 1NRBA 2LY5A 2NY8X 3LDQA 3E7UX 1NGFA 3FZMA 1ATRA 1ZVEA 2YILA 5AQQA 1JZAA 5FPMA 3ATVA 5AQUA 2M8BB 3KOWA 2LKBA 3M3ZA 5F2RA 1L4VA 2K35A 2N66A 1PX9A 3A8YA 1PTXA 3KOYA 3KHWA 1NGBA 1NGIA
chains in the Genus database with same CATH topology
2LR3A 4HE7A 1ICAA 1JXCA 1T7EA 1SN4A 2GL1A 1JKZA 1BRZA 1VNAA 5KK4A 1N4NA 1T7AA 4AEIA 2E3FA 1I6FA 1FH3A 1VNBA 1DJTA 2A7TA 1P0AA 2ATBA 4AAZA 1I2VA 1LQIA 2LY6A 2KPYA 1AHOA 2LJMA 2LT8A 1ZYVA 4KYPA 1MR4A 1BMRA 1B7DA 1ZUTA 2B68A 1BCGA 2I61A 1GPTA 2YEOA 1DQ7A 2YC1C 1ZU3A 4CQKA 1P00A 1AYJA 1TI5A 1SNBA 2E3GA 1I2UA 1OZZA 2LJ7A 1ZFUA 1OMYA 1MYNA 1WT7A 5CY0A 1BK8A 1T7BA 1C55A 1NRAA 2KYQA 1PE4A 1WMTA 2KBHA 2N2QA 2KJAA 1GPSA 1CHZA 1I6GA 2BRZA 2LI7A 1NH5A 3E7RL 3PSMA 1NE5A 4AB0A 2SN3A 1SN1A 1WWNA 1LQHA 1T1TA 2N2RA 1LQQA 1ZYWA 1CN2A 2KGQA 2KBJA 2ASCA 2NY9X 2B3CA 1B3CA 2KBKA 1ZVGA 2E0HA 1T0ZA 2N69A 1KV0A 1NPIA 4V1DC 2YBRC 4UJ0A 1SEGA 2MZ0A 2KSKA 4HHFA 1C56A 1NRBA 2LY5A 2NY8X 3E7UX 1ZVEA 1JZAA 2M8BB 2LKBA 1L4VA 2N66A 1PX9A 1PTXA 1JZBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LR3 A;  4HE7 A;  1ICA A;  1JXC A;  1T7E A;  1SN4 A;  2GL1 A;  1JKZ A;  1BRZ A;  1VNA A;  5KK4 A;  1N4N A;  1T7A A;  4AEI A;  2E3F A;  1I6F A;  1FH3 A;  1VNB A;  1DJT A;  2A7T A;  1P0A A;  2ATB A;  4AAZ A;  1I2V A;  1LQI A;  2LY6 A;  2KPY A;  1AHO A;  2LJM A;  2LT8 A;  1ZYV A;  4KYP A;  1MR4 A;  1BMR A;  1B7D A;  1ZUT A;  2B68 A;  1BCG A;  2I61 A;  1GPT A;  2YEO A;  1DQ7 A;  2YC1 C;  1ZU3 A;  4CQK A;  1P00 A;  1AYJ A;  1TI5 A;  1SNB A;  2E3G A;  1I2U A;  1OZZ A;  2LJ7 A;  1ZFU A;  1OMY A;  1MYN A;  1WT7 A;  5CY0 A;  1BK8 A;  1T7B A;  1C55 A;  1NRA A;  2KYQ A;  1PE4 A;  1WMT A;  2KBH A;  2N2Q A;  2KJA A;  1GPS A;  1CHZ A;  1I6G A;  2BRZ A;  2LI7 A;  1NH5 A;  3E7R L;  3PSM A;  1NE5 A;  4AB0 A;  2SN3 A;  1SN1 A;  1WWN A;  1LQH A;  1T1T A;  2N2R A;  1LQQ A;  1ZYW A;  1CN2 A;  2KGQ A;  2KBJ A;  2ASC A;  2NY9 X;  2B3C A;  1B3C A;  2KBK A;  1ZVG A;  2E0H A;  1T0Z A;  2N69 A;  1KV0 A;  1NPI A;  4V1D C;  2YBR C;  4UJ0 A;  1SEG A;  2MZ0 A;  2KSK A;  4HHF A;  1C56 A;  1NRB A;  2LY5 A;  2NY8 X;  3E7U X;  1ZVE A;  1JZA A;  2M8B B;  2LKB A;  1L4V A;  2N66 A;  1PX9 A;  1PTX A;  1JZB A; 
#chains in the Genus database with same CATH topology
 2LR3 A;  4HE7 A;  1ICA A;  1JXC A;  1T7E A;  4KBO A;  1SN4 A;  2GL1 A;  2E8A A;  5AR0 A;  1JKZ A;  1QQN A;  3BK3 C;  5AQM A;  1K8B A;  3L6Q A;  1HX1 A;  5AQT A;  1BRZ A;  5FPD A;  1POI A;  1VNA A;  5KK4 A;  1N4N A;  3C7N B;  3HSC A;  1T7A A;  3LDP A;  3QFP A;  2E3F A;  4AEI A;  1QQM A;  1I6F A;  1FH3 A;  2GMO A;  3KC6 A;  1VNB A;  5EY4 A;  3QFU A;  3D2F B;  1DJT A;  2A7T A;  1P0A A;  2ATB A;  4AAZ A;  1I2V A;  5EXW A;  1LQI A;  4H5V A;  5AQH A;  2QWP A;  2LY6 A;  3ATU A;  3AY9 A;  1ATS A;  2QXL A;  3GKU A;  3KOX A;  5AQF A;  2KHO A;  1DKG D;  5AQN A;  1BA0 A;  1NGD A;  4H5W A;  2KPY A;  1AHO A;  2LJM A;  3QML A;  2QW9 A;  2QWN A;  2LT8 A;  1ZYV A;  2E2F A;  2QWR A;  4KYP A;  2BUP A;  1MR4 A;  1YUW A;  2QWO A;  5AQZ A;  1BMR A;  5AQR A;  3SF4 D;  1B7D A;  1ZUT A;  3FZK A;  3KP0 A;  2LN8 A;  5EVZ A;  1NGE A;  2B68 A;  1BCG A;  3C7N A;  2I61 A;  4FSV A;  2D56 A;  5AQY A;  1GPT A;  5AQJ A;  3FZH A;  2YEO A;  4IO8 A;  2JDQ D;  1DQ7 A;  3FE1 A;  5AQL A;  1UGL A;  2VY6 A;  5FPN A;  5BPN A;  3D2F A;  2YC1 C;  1ZU3 A;  3JXU A;  3LDL A;  4UAE F;  3I33 A;  1P00 A;  4GNI A;  4CQK A;  1TI5 A;  1BUP A;  1SNB A;  2E3G A;  1AYJ A;  1I2U A;  1OZZ A;  5BN9 A;  2LJ7 A;  3LDO A;  5EX5 A;  1ZFU A;  1OMY A;  4H5R A;  2QWQ A;  5AQO A;  5AQS A;  1MYN A;  1WT7 A;  5BPL A;  5CY0 A;  1BK8 A;  2MBK A;  1T7B A;  1C55 A;  1NRA A;  2KYQ A;  3D2E B;  4UAD E;  2QWL A;  5AQW A;  1PE4 A;  3KOZ A;  5BPM A;  1QQO A;  1NGH A;  1WMT A;  2KBH A;  2N2Q A;  2KJA A;  2V7Z A;  1GPS A;  1CHZ A;  1I6G A;  2BRZ A;  2LI7 A;  3R2V A;  1NH5 A;  3E7R L;  1BA1 A;  3PSM A;  1NGC A;  1NGA A;  1HJO A;  1KAX A;  1NE5 A;  5BN8 A;  5F0X A;  5AQP A;  4AB0 A;  2SN3 A;  2E88 A;  2YIO A;  3CQX A;  4H5T A;  1KAY A;  2MN5 A;  1SN1 A;  5F1X A;  1WWN A;  1LQH A;  1T1T A;  3L4I A;  2QWM A;  2N2R A;  5AQI A;  5AQG A;  1LQQ A;  3GL1 A;  3L56 A;  1ZYW A;  3LDN A;  1JZB A;  3GDQ A;  3KP1 A;  2KGQ A;  1CN2 A;  2ASC A;  2KBJ A;  2NY9 X;  1XRS B;  2B3C A;  1B3C A;  4FL9 A;  2KBK A;  1ZVG A;  5AQK A;  2E0H A;  1T0Z A;  2G2K A;  4UAF E;  1NGJ A;  4HWI A;  5AQV A;  3KVG A;  2N69 A;  1KV0 A;  1NPI A;  3IUC A;  3FZL A;  3QI7 A;  4H5N A;  3D2E A;  1KAZ A;  1NGG A;  2YBR C;  2YIP A;  4V1D C;  4UJ0 A;  3FZF A;  1HPM A;  1SEG A;  2MZ0 A;  2KSK A;  4HHF A;  5AQX A;  1C56 A;  1S3X A;  5FPE A;  3CW4 A;  1NRB A;  2LY5 A;  2NY8 X;  3LDQ A;  3E7U X;  1NGF A;  3FZM A;  1ATR A;  1ZVE A;  2YIL A;  5AQQ A;  1JZA A;  5FPM A;  3ATV A;  5AQU A;  2M8B B;  3KOW A;  2LKB A;  3M3Z A;  5F2R A;  1L4V A;  2K35 A;  2N66 A;  1PX9 A;  3A8Y A;  1PTX A;  3KOY A;  3KHW A;  1NGB A;  1NGI A; 
#chains in the Genus database with same CATH homology
 2LR3 A;  4HE7 A;  1ICA A;  1JXC A;  1T7E A;  1SN4 A;  2GL1 A;  1JKZ A;  1BRZ A;  1VNA A;  5KK4 A;  1N4N A;  1T7A A;  4AEI A;  2E3F A;  1I6F A;  1FH3 A;  1VNB A;  1DJT A;  2A7T A;  1P0A A;  2ATB A;  4AAZ A;  1I2V A;  1LQI A;  2LY6 A;  2KPY A;  1AHO A;  2LJM A;  2LT8 A;  1ZYV A;  4KYP A;  1MR4 A;  1BMR A;  1B7D A;  1ZUT A;  2B68 A;  1BCG A;  2I61 A;  1GPT A;  2YEO A;  1DQ7 A;  2YC1 C;  1ZU3 A;  4CQK A;  1P00 A;  1AYJ A;  1TI5 A;  1SNB A;  2E3G A;  1I2U A;  1OZZ A;  2LJ7 A;  1ZFU A;  1OMY A;  1MYN A;  1WT7 A;  5CY0 A;  1BK8 A;  1T7B A;  1C55 A;  1NRA A;  2KYQ A;  1PE4 A;  1WMT A;  2KBH A;  2N2Q A;  2KJA A;  1GPS A;  1CHZ A;  1I6G A;  2BRZ A;  2LI7 A;  1NH5 A;  3E7R L;  3PSM A;  1NE5 A;  4AB0 A;  2SN3 A;  1SN1 A;  1WWN A;  1LQH A;  1T1T A;  2N2R A;  1LQQ A;  1ZYW A;  1CN2 A;  2KGQ A;  2KBJ A;  2ASC A;  2NY9 X;  2B3C A;  1B3C A;  2KBK A;  1ZVG A;  2E0H A;  1T0Z A;  2N69 A;  1KV0 A;  1NPI A;  4V1D C;  2YBR C;  4UJ0 A;  1SEG A;  2MZ0 A;  2KSK A;  4HHF A;  1C56 A;  1NRB A;  2LY5 A;  2NY8 X;  3E7U X;  1ZVE A;  1JZA A;  2M8B B;  2LKB A;  1L4V A;  2N66 A;  1PX9 A;  1PTX A;  1JZB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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