4AEIA

Crystal structure of the aahii-fab4c1 complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
64
structure length
64
Chain Sequence
VKDGYIVDDVNCTYFCGRNAYCNEECTKLKGESGYCQWASPYGNACYCYKLPDHVRTKGPGRCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
pubmed doi rcsb
molecule tags Immune system/toxin
molecule keywords ALPHA-MAMMAL TOXIN AAH2
total genus 19
structure length 64
sequence length 64
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 4aeiA00
2N2QA 4AEIA 2N69A 1NPIA 1BRZA 1B7DA 1N4NA 1ZVGA 5CY0A 1MYNA 4HE7A 4UJ0A 2KSKA 1ICAA 2NY9X 2B68A 2MZ0A 3E7UX 2LJ7A 3PSMA 1C56A 1CN2A 1OMYA 1SEGA 5KK4A 1NRAA 2E3FA 2ATBA 1JZAA 1JXCA 1ZYWA 2KBJA 2GL1A 2KGQA 1L4VA 4HHFA 2B3CA 2ASCA 2KBHA 1JKZA 1PTXA 2E3GA 1B3CA 1ZUTA 1CHZA 1ZYVA 2M8BB 1PE4A 1I6FA 1FH3A 3E7RL 1GPSA 1AYJA 1P00A 1ZVEA 1VNAA 2SN3A 2KPYA 1LQIA 2N66A 2E0HA 2LJMA 1T0ZA 2LT8A 2KYQA 1WMTA 2LI7A 1DQ7A 1PX9A 1TI5A 1ZU3A 2A7TA 1BK8A 1WWNA 1BMRA 4KYPA 1I6GA 1DJTA 1GPTA 2BRZA 1OZZA 1I2VA 2YC1C 1VNBA 2KJAA 1LQQA 1T1TA 2LY5A 4AAZA 2N2RA 2KBKA 1ZFUA 1I2UA 1LQHA 1NE5A 1AHOA 1WT7A 1NRBA 4CQKA 2NY8X 4AB0A 1C55A 1P0AA 1KV0A 2YBRC 1BCGA 1T7BA 2I61A 2YEOA 2LKBA 1SNBA 1T7AA 2LY6A 1JZBA 4V1DC 1T7EA 1SN4A 1MR4A 1NH5A 2LR3A 1SN1A
chains in the Genus database with same CATH superfamily
3CW4A 2N2QA 4AEIA 2N69A 3LDQA 1DKGD 3D2EB 1NPIA 5AQTA 1UGLA 1BRZA 1B7DA 3QFUA 3QI7A 5AQHA 1N4NA 1ZVGA 2KHOA 5CY0A 1MYNA 4HE7A 3KHWA 3C7NB 2QWMA 5AQYA 4UJ0A 1KAYA 5AQOA 2KSKA 1ICAA 1NGJA 5FPEA 3QFPA 5BPMA 2NY9X 2B68A 2MZ0A 3GDQA 4UAFE 5EX5A 3E7UX 1ATSA 5AQWA 2LJ7A 3M3ZA 4H5WA 5AQXA 3PSMA 2MN5A 1C56A 3FE1A 1OMYA 1SEGA 5AQQA 2YIOA 5FPMA 2YIPA 5KK4A 1CN2A 1NRAA 2E3FA 2ATBA 1NGHA 3CQXA 1QQMA 1NGEA 5BN9A 1JZAA 1NGFA 1JXCA 1ZYWA 4H5TA 2QWOA 3QMLA 1POIA 2KBJA 3LDOA 4HWIA 4GNIA 5EXWA 2GL1A 1HX1A 2KGQA 2E8AA 2MBKA 2QWQA 4HHFA 5F0XA 1L4VA 5AQVA 3L4IA 2VY6A 2B3CA 3KOXA 2ASCA 4H5VA 2KBHA 5AQIA 5AQNA 1JKZA 1PTXA 2E3GA 3L6QA 1K8BA 1YUWA 1B3CA 1ZUTA 1CHZA 1ZYVA 2D56A 2M8BB 1PE4A 3I33A 3IUCA 1I6FA 4H5NA 3BK3C 3E7RL 5AQKA 1FH3A 1GPSA 1HPMA 2QW9A 1AYJA 5BPNA 1BUPA 1P00A 3KP0A 5BPLA 5AQRA 1ZVEA 2YILA 1VNAA 2QWPA 3D2EA 1BA0A 4IO8A 2SN3A 3KP1A 2KPYA 3KOYA 2QXLA 1LQIA 2N66A 3D2FB 3C7NA 3KVGA 2V7ZA 1KAZA 2E0HA 1ATRA 2LJMA 5BN8A 1NGBA 1QQOA 1T0ZA 2LT8A 1QQNA 2KYQA 2E88A 1WMTA 2QWNA 3JXUA 3GL1A 3LDPA 1KAXA 5AQFA 2LI7A 3ATVA 5AQSA 5F2RA 1DQ7A 1PX9A 3FZKA 1TI5A 1ZU3A 2A7TA 5EVZA 1WWNA 1BK8A 1BMRA 4KYPA 4UADE 2GMOA 1DJTA 3FZMA 1I6GA 1GPTA 2BRZA 1NGDA 2E2FA 1NGGA 1OZZA 3FZHA 4FL9A 1I2VA 3FZLA 5AQJA 1HJOA 5AQLA 2YC1C 5AR0A 5FPNA 5AQMA 1XRSB 5F1XA 1VNBA 1NGAA 2KJAA 3AY9A 3KOWA 1LQQA 1T1TA 2JDQD 2LY5A 2N2RA 2BUPA 3A8YA 2KBKA 3GKUA 4AAZA 2QWLA 1ZFUA 5EY4A 3FZFA 5AQZA 1I2UA 1LQHA 3LDNA 2G2KA 4H5RA 1S3XA 1NE5A 1AHOA 1WT7A 1NRBA 3KOZA 2K35A 2NY8X 3SF4D 4CQKA 2QWRA 4KBOA 4AB0A 1C55A 2LN8A 1P0AA 3D2FA 3ATUA 3R2VA 1KV0A 2YBRC 1BCGA 1T7BA 5AQUA 2I61A 1NGIA 5AQGA 2YEOA 2LKBA 3LDLA 1SNBA 1T7AA 2LY6A 4UAEF 5FPDA 1JZBA 3HSCA 4V1DC 1T7EA 1SN4A 1MR4A 3L56A 1NH5A 1NGCA 4FSVA 1BA1A 3KC6A 2LR3A 5AQPA 1SN1A
chains in the Genus database with same CATH topology
2N2QA 4AEIA 2N69A 1NPIA 1BRZA 1B7DA 1N4NA 1ZVGA 5CY0A 1MYNA 4HE7A 4UJ0A 2KSKA 1ICAA 2NY9X 2B68A 2MZ0A 3E7UX 2LJ7A 3PSMA 1C56A 1CN2A 1OMYA 1SEGA 5KK4A 1NRAA 2E3FA 2ATBA 1JZAA 1JXCA 1ZYWA 2KBJA 2GL1A 2KGQA 1L4VA 4HHFA 2B3CA 2ASCA 2KBHA 1JKZA 1PTXA 2E3GA 1B3CA 1ZUTA 1CHZA 1ZYVA 2M8BB 1PE4A 1I6FA 1FH3A 3E7RL 1GPSA 1AYJA 1P00A 1ZVEA 1VNAA 2SN3A 2KPYA 1LQIA 2N66A 2E0HA 2LJMA 1T0ZA 2LT8A 2KYQA 1WMTA 2LI7A 1DQ7A 1PX9A 1TI5A 1ZU3A 2A7TA 1BK8A 1WWNA 1BMRA 4KYPA 1I6GA 1DJTA 1GPTA 2BRZA 1OZZA 1I2VA 2YC1C 1VNBA 2KJAA 1LQQA 1T1TA 2LY5A 4AAZA 2N2RA 2KBKA 1ZFUA 1I2UA 1LQHA 1NE5A 1AHOA 1WT7A 1NRBA 4CQKA 2NY8X 4AB0A 1C55A 1P0AA 1KV0A 2YBRC 1BCGA 1T7BA 2I61A 2YEOA 2LKBA 1SNBA 1T7AA 2LY6A 1JZBA 4V1DC 1T7EA 1SN4A 1MR4A 1NH5A 2LR3A 1SN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N2Q A;  4AEI A;  2N69 A;  1NPI A;  1BRZ A;  1B7D A;  1N4N A;  1ZVG A;  5CY0 A;  1MYN A;  4HE7 A;  4UJ0 A;  2KSK A;  1ICA A;  2NY9 X;  2B68 A;  2MZ0 A;  3E7U X;  2LJ7 A;  3PSM A;  1C56 A;  1CN2 A;  1OMY A;  1SEG A;  5KK4 A;  1NRA A;  2E3F A;  2ATB A;  1JZA A;  1JXC A;  1ZYW A;  2KBJ A;  2GL1 A;  2KGQ A;  1L4V A;  4HHF A;  2B3C A;  2ASC A;  2KBH A;  1JKZ A;  1PTX A;  2E3G A;  1B3C A;  1ZUT A;  1CHZ A;  1ZYV A;  2M8B B;  1PE4 A;  1I6F A;  1FH3 A;  3E7R L;  1GPS A;  1AYJ A;  1P00 A;  1ZVE A;  1VNA A;  2SN3 A;  2KPY A;  1LQI A;  2N66 A;  2E0H A;  2LJM A;  1T0Z A;  2LT8 A;  2KYQ A;  1WMT A;  2LI7 A;  1DQ7 A;  1PX9 A;  1TI5 A;  1ZU3 A;  2A7T A;  1BK8 A;  1WWN A;  1BMR A;  4KYP A;  1I6G A;  1DJT A;  1GPT A;  2BRZ A;  1OZZ A;  1I2V A;  2YC1 C;  1VNB A;  2KJA A;  1LQQ A;  1T1T A;  2LY5 A;  4AAZ A;  2N2R A;  2KBK A;  1ZFU A;  1I2U A;  1LQH A;  1NE5 A;  1AHO A;  1WT7 A;  1NRB A;  4CQK A;  2NY8 X;  4AB0 A;  1C55 A;  1P0A A;  1KV0 A;  2YBR C;  1BCG A;  1T7B A;  2I61 A;  2YEO A;  2LKB A;  1SNB A;  1T7A A;  2LY6 A;  1JZB A;  4V1D C;  1T7E A;  1SN4 A;  1MR4 A;  1NH5 A;  2LR3 A;  1SN1 A; 
#chains in the Genus database with same CATH topology
 3CW4 A;  2N2Q A;  4AEI A;  2N69 A;  3LDQ A;  1DKG D;  3D2E B;  1NPI A;  5AQT A;  1UGL A;  1BRZ A;  1B7D A;  3QFU A;  3QI7 A;  5AQH A;  1N4N A;  1ZVG A;  2KHO A;  5CY0 A;  1MYN A;  4HE7 A;  3KHW A;  3C7N B;  2QWM A;  5AQY A;  4UJ0 A;  1KAY A;  5AQO A;  2KSK A;  1ICA A;  1NGJ A;  5FPE A;  3QFP A;  5BPM A;  2NY9 X;  2B68 A;  2MZ0 A;  3GDQ A;  4UAF E;  5EX5 A;  3E7U X;  1ATS A;  5AQW A;  2LJ7 A;  3M3Z A;  4H5W A;  5AQX A;  3PSM A;  2MN5 A;  1C56 A;  3FE1 A;  1OMY A;  1SEG A;  5AQQ A;  2YIO A;  5FPM A;  2YIP A;  5KK4 A;  1CN2 A;  1NRA A;  2E3F A;  2ATB A;  1NGH A;  3CQX A;  1QQM A;  1NGE A;  5BN9 A;  1JZA A;  1NGF A;  1JXC A;  1ZYW A;  4H5T A;  2QWO A;  3QML A;  1POI A;  2KBJ A;  3LDO A;  4HWI A;  4GNI A;  5EXW A;  2GL1 A;  1HX1 A;  2KGQ A;  2E8A A;  2MBK A;  2QWQ A;  4HHF A;  5F0X A;  1L4V A;  5AQV A;  3L4I A;  2VY6 A;  2B3C A;  3KOX A;  2ASC A;  4H5V A;  2KBH A;  5AQI A;  5AQN A;  1JKZ A;  1PTX A;  2E3G A;  3L6Q A;  1K8B A;  1YUW A;  1B3C A;  1ZUT A;  1CHZ A;  1ZYV A;  2D56 A;  2M8B B;  1PE4 A;  3I33 A;  3IUC A;  1I6F A;  4H5N A;  3BK3 C;  3E7R L;  5AQK A;  1FH3 A;  1GPS A;  1HPM A;  2QW9 A;  1AYJ A;  5BPN A;  1BUP A;  1P00 A;  3KP0 A;  5BPL A;  5AQR A;  1ZVE A;  2YIL A;  1VNA A;  2QWP A;  3D2E A;  1BA0 A;  4IO8 A;  2SN3 A;  3KP1 A;  2KPY A;  3KOY A;  2QXL A;  1LQI A;  2N66 A;  3D2F B;  3C7N A;  3KVG A;  2V7Z A;  1KAZ A;  2E0H A;  1ATR A;  2LJM A;  5BN8 A;  1NGB A;  1QQO A;  1T0Z A;  2LT8 A;  1QQN A;  2KYQ A;  2E88 A;  1WMT A;  2QWN A;  3JXU A;  3GL1 A;  3LDP A;  1KAX A;  5AQF A;  2LI7 A;  3ATV A;  5AQS A;  5F2R A;  1DQ7 A;  1PX9 A;  3FZK A;  1TI5 A;  1ZU3 A;  2A7T A;  5EVZ A;  1WWN A;  1BK8 A;  1BMR A;  4KYP A;  4UAD E;  2GMO A;  1DJT A;  3FZM A;  1I6G A;  1GPT A;  2BRZ A;  1NGD A;  2E2F A;  1NGG A;  1OZZ A;  3FZH A;  4FL9 A;  1I2V A;  3FZL A;  5AQJ A;  1HJO A;  5AQL A;  2YC1 C;  5AR0 A;  5FPN A;  5AQM A;  1XRS B;  5F1X A;  1VNB A;  1NGA A;  2KJA A;  3AY9 A;  3KOW A;  1LQQ A;  1T1T A;  2JDQ D;  2LY5 A;  2N2R A;  2BUP A;  3A8Y A;  2KBK A;  3GKU A;  4AAZ A;  2QWL A;  1ZFU A;  5EY4 A;  3FZF A;  5AQZ A;  1I2U A;  1LQH A;  3LDN A;  2G2K A;  4H5R A;  1S3X A;  1NE5 A;  1AHO A;  1WT7 A;  1NRB A;  3KOZ A;  2K35 A;  2NY8 X;  3SF4 D;  4CQK A;  2QWR A;  4KBO A;  4AB0 A;  1C55 A;  2LN8 A;  1P0A A;  3D2F A;  3ATU A;  3R2V A;  1KV0 A;  2YBR C;  1BCG A;  1T7B A;  5AQU A;  2I61 A;  1NGI A;  5AQG A;  2YEO A;  2LKB A;  3LDL A;  1SNB A;  1T7A A;  2LY6 A;  4UAE F;  5FPD A;  1JZB A;  3HSC A;  4V1D C;  1T7E A;  1SN4 A;  1MR4 A;  3L56 A;  1NH5 A;  1NGC A;  4FSV A;  1BA1 A;  3KC6 A;  2LR3 A;  5AQP A;  1SN1 A; 
#chains in the Genus database with same CATH homology
 2N2Q A;  4AEI A;  2N69 A;  1NPI A;  1BRZ A;  1B7D A;  1N4N A;  1ZVG A;  5CY0 A;  1MYN A;  4HE7 A;  4UJ0 A;  2KSK A;  1ICA A;  2NY9 X;  2B68 A;  2MZ0 A;  3E7U X;  2LJ7 A;  3PSM A;  1C56 A;  1CN2 A;  1OMY A;  1SEG A;  5KK4 A;  1NRA A;  2E3F A;  2ATB A;  1JZA A;  1JXC A;  1ZYW A;  2KBJ A;  2GL1 A;  2KGQ A;  1L4V A;  4HHF A;  2B3C A;  2ASC A;  2KBH A;  1JKZ A;  1PTX A;  2E3G A;  1B3C A;  1ZUT A;  1CHZ A;  1ZYV A;  2M8B B;  1PE4 A;  1I6F A;  1FH3 A;  3E7R L;  1GPS A;  1AYJ A;  1P00 A;  1ZVE A;  1VNA A;  2SN3 A;  2KPY A;  1LQI A;  2N66 A;  2E0H A;  2LJM A;  1T0Z A;  2LT8 A;  2KYQ A;  1WMT A;  2LI7 A;  1DQ7 A;  1PX9 A;  1TI5 A;  1ZU3 A;  2A7T A;  1BK8 A;  1WWN A;  1BMR A;  4KYP A;  1I6G A;  1DJT A;  1GPT A;  2BRZ A;  1OZZ A;  1I2V A;  2YC1 C;  1VNB A;  2KJA A;  1LQQ A;  1T1T A;  2LY5 A;  4AAZ A;  2N2R A;  2KBK A;  1ZFU A;  1I2U A;  1LQH A;  1NE5 A;  1AHO A;  1WT7 A;  1NRB A;  4CQK A;  2NY8 X;  4AB0 A;  1C55 A;  1P0A A;  1KV0 A;  2YBR C;  1BCG A;  1T7B A;  2I61 A;  2YEO A;  2LKB A;  1SNB A;  1T7A A;  2LY6 A;  1JZB A;  4V1D C;  1T7E A;  1SN4 A;  1MR4 A;  1NH5 A;  2LR3 A;  1SN1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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