1WT7A

Solution structure of butx-mtx: a butantoxin-maurotoxin chimera
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
41
structure length
41
Chain Sequence
WCSTCLDLACTGSKDCYAPCRKQTGCPNAKCINKSCKCYGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.
pubmed doi rcsb
molecule tags Toxin
molecule keywords BuTX-MTX
total genus 6
structure length 41
sequence length 41
ec nomenclature
pdb deposition date 2004-11-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1wt7A00
1OZZA 1NPIA 1LQIA 1PE4A 1ZVGA 2KYQA 1ZVEA 1I2UA 1B3CA 3PSMA 2KPYA 1BRZA 3E7UX 1FH3A 2LI7A 2I61A 1GPTA 2E0HA 2YEOA 2KBHA 2N2RA 2MZ0A 1I2VA 1ZYVA 1SEGA 2KSKA 1DJTA 2YBRC 1PTXA 1B7DA 1P00A 1ZU3A 2NY9X 1SN4A 1CHZA 2LR3A 1JZAA 4V1DC 1NRAA 1WMTA 4AEIA 1ZFUA 1SNBA 1VNBA 4KYPA 1MYNA 2LJ7A 1GPSA 4HE7A 1ZUTA 2N2QA 1I6GA 1ICAA 2E3FA 2B3CA 2KGQA 2N69A 4AB0A 1SN1A 1NH5A 1T0ZA 2E3GA 2GL1A 5KK4A 2A7TA 1PX9A 3E7RL 1NE5A 1BMRA 1VNAA 4HHFA 2LY5A 1OMYA 1P0AA 1NRBA 1KV0A 2NY8X 1ZYWA 1LQQA 2LJMA 1BK8A 1L4VA 1WT7A 1C56A 1T7BA 1LQHA 1BCGA 2KJAA 1CN2A 2ASCA 1WWNA 1AHOA 1C55A 2YC1C 1JZBA 1JKZA 2BRZA 1TI5A 2LT8A 4AAZA 4UJ0A 2M8BB 1MR4A 1AYJA 1T7AA 1T1TA 2LY6A 5CY0A 1I6FA 1JXCA 1T7EA 2LKBA 1N4NA 2B68A 2SN3A 1DQ7A 2N66A 2ATBA 2KBJA 4CQKA 2KBKA
chains in the Genus database with same CATH superfamily
1NGHA 1OZZA 1S3XA 2E8AA 1NPIA 1BA1A 1YUWA 2E2FA 4H5NA 1LQIA 1POIA 4H5WA 5AQVA 1PE4A 1ZVGA 2KYQA 1ZVEA 3D2EA 1QQNA 3FZKA 3KHWA 3KP1A 3KP0A 3PSMA 4H5TA 5AQWA 1B3CA 3GDQA 5AQOA 2KPYA 2QW9A 3KOXA 3E7UX 1BRZA 1KAYA 2V7ZA 2LI7A 5AQMA 1NGGA 3KOZA 3LDQA 5AQQA 1FH3A 1NGIA 2I61A 1GPTA 5AQLA 5AQGA 2KHOA 5AQKA 1ATSA 3IUCA 3KVGA 4FSVA 2E0HA 2YEOA 5BPMA 3I33A 5F1XA 2KBHA 2N2RA 5AQJA 5AQXA 2VY6A 1NGDA 2LN8A 1HPMA 2GMOA 2MZ0A 3CW4A 1I2VA 1NGBA 1ZYVA 1SEGA 3HSCA 1BUPA 1DJTA 2KSKA 3LDLA 3GKUA 3KC6A 5BPNA 2YBRC 1PTXA 1B7DA 3KOYA 1P00A 1ZU3A 5EXWA 1KAZA 2YILA 2NY9X 1SN4A 3LDNA 2QWNA 5EY4A 1CHZA 2LR3A 1JZAA 4V1DC 1NRAA 1WMTA 4H5RA 4UADE 2QWLA 5AQHA 4AEIA 1KAXA 1ZFUA 2MBKA 2YIPA 1SNBA 2MN5A 2QWRA 1VNBA 4KYPA 5AQSA 5BN9A 3C7NB 1MYNA 2LJ7A 3R2VA 1GPSA 5FPDA 4HE7A 1QQMA 2QWQA 1ZUTA 3KOWA 3SF4D 2QXLA 3ATUA 3C7NA 2N2QA 3L6QA 4UAFE 5AQTA 3L4IA 1I6GA 1ICAA 5AQUA 3LDPA 2B3CA 2E3FA 2KGQA 2N69A 3QFPA 4AB0A 1SN1A 1NH5A 1BA0A 1T0ZA 2E3GA 2G2KA 5BN8A 3BK3C 2GL1A 4IO8A 2K35A 3QI7A 5EX5A 5KK4A 2KBKA 3L56A 2A7TA 1PX9A 1ATRA 2YIOA 3CQXA 1NE5A 3E7RL 3LDOA 5FPNA 1BMRA 4KBOA 5AQYA 4FL9A 1VNAA 3QFUA 5FPMA 4HHFA 2LY5A 2E88A 1OMYA 3GL1A 1P0AA 1NRBA 1HJOA 1KV0A 1I2UA 2NY8X 5BPLA 3JXUA 1ZYWA 1LQQA 2LJMA 2KBJA 3D2FB 3A8YA 3FZMA 1BK8A 5AQNA 1L4VA 4HWIA 1WT7A 1C56A 2BUPA 1NGAA 3M3ZA 1UGLA 1LQHA 3FZHA 1BCGA 2QWMA 2KJAA 5AQRA 1CN2A 2ASCA 3ATVA 1WWNA 3D2FA 4GNIA 1AHOA 1C55A 1XRSB 2YC1C 5AQZA 1JZBA 1JKZA 2BRZA 5AQPA 4UAEF 5EVZA 5FPEA 1TI5A 2LT8A 4AAZA 1NGFA 4UJ0A 2M8BB 5AQIA 1K8BA 1MR4A 2JDQD 1AYJA 1T7AA 3FZLA 1T1TA 5AR0A 1NGCA 1QQOA 2LY6A 1NGEA 5CY0A 2QWPA 1I6FA 1JXCA 1NGJA 1T7EA 5F2RA 2LKBA 1DKGD 5AQFA 5F0XA 1N4NA 2B68A 2D56A 2SN3A 3AY9A 2QWOA 4H5VA 3FZFA 1DQ7A 2N66A 3QMLA 2ATBA 3D2EB 3FE1A 1HX1A 4CQKA 1T7BA
chains in the Genus database with same CATH topology
1OZZA 1NPIA 1LQIA 1PE4A 1ZVGA 2KYQA 1ZVEA 1I2UA 1B3CA 3PSMA 2KPYA 1BRZA 3E7UX 1FH3A 2LI7A 2I61A 1GPTA 2E0HA 2YEOA 2KBHA 2N2RA 2MZ0A 1I2VA 1ZYVA 1SEGA 2KSKA 1DJTA 2YBRC 1PTXA 1B7DA 1P00A 1ZU3A 2NY9X 1SN4A 1CHZA 2LR3A 1JZAA 4V1DC 1NRAA 1WMTA 4AEIA 1ZFUA 1SNBA 1VNBA 4KYPA 1MYNA 2LJ7A 1GPSA 4HE7A 1ZUTA 2N2QA 1I6GA 1ICAA 2E3FA 2B3CA 2KGQA 2N69A 4AB0A 1SN1A 1NH5A 1T0ZA 2E3GA 2GL1A 5KK4A 2A7TA 1PX9A 3E7RL 1NE5A 1BMRA 1VNAA 4HHFA 2LY5A 1OMYA 1P0AA 1NRBA 1KV0A 2NY8X 1ZYWA 1LQQA 2LJMA 1BK8A 1L4VA 1WT7A 1C56A 1T7BA 1LQHA 1BCGA 2KJAA 1CN2A 2ASCA 1WWNA 1AHOA 1C55A 2YC1C 1JZBA 1JKZA 2BRZA 1TI5A 2LT8A 4AAZA 4UJ0A 2M8BB 1MR4A 1AYJA 1T7AA 1T1TA 2LY6A 5CY0A 1I6FA 1JXCA 1T7EA 2LKBA 1N4NA 2B68A 2SN3A 1DQ7A 2N66A 2ATBA 2KBJA 4CQKA 2KBKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OZZ A;  1NPI A;  1LQI A;  1PE4 A;  1ZVG A;  2KYQ A;  1ZVE A;  1I2U A;  1B3C A;  3PSM A;  2KPY A;  1BRZ A;  3E7U X;  1FH3 A;  2LI7 A;  2I61 A;  1GPT A;  2E0H A;  2YEO A;  2KBH A;  2N2R A;  2MZ0 A;  1I2V A;  1ZYV A;  1SEG A;  2KSK A;  1DJT A;  2YBR C;  1PTX A;  1B7D A;  1P00 A;  1ZU3 A;  2NY9 X;  1SN4 A;  1CHZ A;  2LR3 A;  1JZA A;  4V1D C;  1NRA A;  1WMT A;  4AEI A;  1ZFU A;  1SNB A;  1VNB A;  4KYP A;  1MYN A;  2LJ7 A;  1GPS A;  4HE7 A;  1ZUT A;  2N2Q A;  1I6G A;  1ICA A;  2E3F A;  2B3C A;  2KGQ A;  2N69 A;  4AB0 A;  1SN1 A;  1NH5 A;  1T0Z A;  2E3G A;  2GL1 A;  5KK4 A;  2A7T A;  1PX9 A;  3E7R L;  1NE5 A;  1BMR A;  1VNA A;  4HHF A;  2LY5 A;  1OMY A;  1P0A A;  1NRB A;  1KV0 A;  2NY8 X;  1ZYW A;  1LQQ A;  2LJM A;  1BK8 A;  1L4V A;  1WT7 A;  1C56 A;  1T7B A;  1LQH A;  1BCG A;  2KJA A;  1CN2 A;  2ASC A;  1WWN A;  1AHO A;  1C55 A;  2YC1 C;  1JZB A;  1JKZ A;  2BRZ A;  1TI5 A;  2LT8 A;  4AAZ A;  4UJ0 A;  2M8B B;  1MR4 A;  1AYJ A;  1T7A A;  1T1T A;  2LY6 A;  5CY0 A;  1I6F A;  1JXC A;  1T7E A;  2LKB A;  1N4N A;  2B68 A;  2SN3 A;  1DQ7 A;  2N66 A;  2ATB A;  2KBJ A;  4CQK A;  2KBK A; 
#chains in the Genus database with same CATH topology
 1NGH A;  1OZZ A;  1S3X A;  2E8A A;  1NPI A;  1BA1 A;  1YUW A;  2E2F A;  4H5N A;  1LQI A;  1POI A;  4H5W A;  5AQV A;  1PE4 A;  1ZVG A;  2KYQ A;  1ZVE A;  3D2E A;  1QQN A;  3FZK A;  3KHW A;  3KP1 A;  3KP0 A;  3PSM A;  4H5T A;  5AQW A;  1B3C A;  3GDQ A;  5AQO A;  2KPY A;  2QW9 A;  3KOX A;  3E7U X;  1BRZ A;  1KAY A;  2V7Z A;  2LI7 A;  5AQM A;  1NGG A;  3KOZ A;  3LDQ A;  5AQQ A;  1FH3 A;  1NGI A;  2I61 A;  1GPT A;  5AQL A;  5AQG A;  2KHO A;  5AQK A;  1ATS A;  3IUC A;  3KVG A;  4FSV A;  2E0H A;  2YEO A;  5BPM A;  3I33 A;  5F1X A;  2KBH A;  2N2R A;  5AQJ A;  5AQX A;  2VY6 A;  1NGD A;  2LN8 A;  1HPM A;  2GMO A;  2MZ0 A;  3CW4 A;  1I2V A;  1NGB A;  1ZYV A;  1SEG A;  3HSC A;  1BUP A;  1DJT A;  2KSK A;  3LDL A;  3GKU A;  3KC6 A;  5BPN A;  2YBR C;  1PTX A;  1B7D A;  3KOY A;  1P00 A;  1ZU3 A;  5EXW A;  1KAZ A;  2YIL A;  2NY9 X;  1SN4 A;  3LDN A;  2QWN A;  5EY4 A;  1CHZ A;  2LR3 A;  1JZA A;  4V1D C;  1NRA A;  1WMT A;  4H5R A;  4UAD E;  2QWL A;  5AQH A;  4AEI A;  1KAX A;  1ZFU A;  2MBK A;  2YIP A;  1SNB A;  2MN5 A;  2QWR A;  1VNB A;  4KYP A;  5AQS A;  5BN9 A;  3C7N B;  1MYN A;  2LJ7 A;  3R2V A;  1GPS A;  5FPD A;  4HE7 A;  1QQM A;  2QWQ A;  1ZUT A;  3KOW A;  3SF4 D;  2QXL A;  3ATU A;  3C7N A;  2N2Q A;  3L6Q A;  4UAF E;  5AQT A;  3L4I A;  1I6G A;  1ICA A;  5AQU A;  3LDP A;  2B3C A;  2E3F A;  2KGQ A;  2N69 A;  3QFP A;  4AB0 A;  1SN1 A;  1NH5 A;  1BA0 A;  1T0Z A;  2E3G A;  2G2K A;  5BN8 A;  3BK3 C;  2GL1 A;  4IO8 A;  2K35 A;  3QI7 A;  5EX5 A;  5KK4 A;  2KBK A;  3L56 A;  2A7T A;  1PX9 A;  1ATR A;  2YIO A;  3CQX A;  1NE5 A;  3E7R L;  3LDO A;  5FPN A;  1BMR A;  4KBO A;  5AQY A;  4FL9 A;  1VNA A;  3QFU A;  5FPM A;  4HHF A;  2LY5 A;  2E88 A;  1OMY A;  3GL1 A;  1P0A A;  1NRB A;  1HJO A;  1KV0 A;  1I2U A;  2NY8 X;  5BPL A;  3JXU A;  1ZYW A;  1LQQ A;  2LJM A;  2KBJ A;  3D2F B;  3A8Y A;  3FZM A;  1BK8 A;  5AQN A;  1L4V A;  4HWI A;  1WT7 A;  1C56 A;  2BUP A;  1NGA A;  3M3Z A;  1UGL A;  1LQH A;  3FZH A;  1BCG A;  2QWM A;  2KJA A;  5AQR A;  1CN2 A;  2ASC A;  3ATV A;  1WWN A;  3D2F A;  4GNI A;  1AHO A;  1C55 A;  1XRS B;  2YC1 C;  5AQZ A;  1JZB A;  1JKZ A;  2BRZ A;  5AQP A;  4UAE F;  5EVZ A;  5FPE A;  1TI5 A;  2LT8 A;  4AAZ A;  1NGF A;  4UJ0 A;  2M8B B;  5AQI A;  1K8B A;  1MR4 A;  2JDQ D;  1AYJ A;  1T7A A;  3FZL A;  1T1T A;  5AR0 A;  1NGC A;  1QQO A;  2LY6 A;  1NGE A;  5CY0 A;  2QWP A;  1I6F A;  1JXC A;  1NGJ A;  1T7E A;  5F2R A;  2LKB A;  1DKG D;  5AQF A;  5F0X A;  1N4N A;  2B68 A;  2D56 A;  2SN3 A;  3AY9 A;  2QWO A;  4H5V A;  3FZF A;  1DQ7 A;  2N66 A;  3QML A;  2ATB A;  3D2E B;  3FE1 A;  1HX1 A;  4CQK A;  1T7B A; 
#chains in the Genus database with same CATH homology
 1OZZ A;  1NPI A;  1LQI A;  1PE4 A;  1ZVG A;  2KYQ A;  1ZVE A;  1I2U A;  1B3C A;  3PSM A;  2KPY A;  1BRZ A;  3E7U X;  1FH3 A;  2LI7 A;  2I61 A;  1GPT A;  2E0H A;  2YEO A;  2KBH A;  2N2R A;  2MZ0 A;  1I2V A;  1ZYV A;  1SEG A;  2KSK A;  1DJT A;  2YBR C;  1PTX A;  1B7D A;  1P00 A;  1ZU3 A;  2NY9 X;  1SN4 A;  1CHZ A;  2LR3 A;  1JZA A;  4V1D C;  1NRA A;  1WMT A;  4AEI A;  1ZFU A;  1SNB A;  1VNB A;  4KYP A;  1MYN A;  2LJ7 A;  1GPS A;  4HE7 A;  1ZUT A;  2N2Q A;  1I6G A;  1ICA A;  2E3F A;  2B3C A;  2KGQ A;  2N69 A;  4AB0 A;  1SN1 A;  1NH5 A;  1T0Z A;  2E3G A;  2GL1 A;  5KK4 A;  2A7T A;  1PX9 A;  3E7R L;  1NE5 A;  1BMR A;  1VNA A;  4HHF A;  2LY5 A;  1OMY A;  1P0A A;  1NRB A;  1KV0 A;  2NY8 X;  1ZYW A;  1LQQ A;  2LJM A;  1BK8 A;  1L4V A;  1WT7 A;  1C56 A;  1T7B A;  1LQH A;  1BCG A;  2KJA A;  1CN2 A;  2ASC A;  1WWN A;  1AHO A;  1C55 A;  2YC1 C;  1JZB A;  1JKZ A;  2BRZ A;  1TI5 A;  2LT8 A;  4AAZ A;  4UJ0 A;  2M8B B;  1MR4 A;  1AYJ A;  1T7A A;  1T1T A;  2LY6 A;  5CY0 A;  1I6F A;  1JXC A;  1T7E A;  2LKB A;  1N4N A;  2B68 A;  2SN3 A;  1DQ7 A;  2N66 A;  2ATB A;  2KBJ A;  4CQK A;  2KBK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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