2N2QA

Nmr solution structure of hsafp1
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
54
structure length
54
Chain Sequence
DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Heuchera sanguinea
molecule keywords Defensin-like protein 1
total genus 10
structure length 54
sequence length 54
ec nomenclature
pdb deposition date 2015-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00304 Gamma-thionin Gamma-thionin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2n2qA00
2MZ0A 1WWNA 1TI5A 2LJMA 4HHFA 2LI7A 2ASCA 1JKZA 1LQHA 4V1DC 1I6GA 1ZYVA 1BRZA 3PSMA 1ZFUA 2SN3A 1B7DA 1MR4A 1NPIA 1VNBA 1ZYWA 4UJ0A 1NRBA 2LY5A 4HE7A 5CY0A 5KK4A 2LT8A 2YC1C 1OMYA 1ICAA 1ZVEA 1SN4A 2LR3A 1I6FA 2I61A 1T7AA 1L4VA 3E7UX 1VNAA 1T7EA 1T0ZA 2A7TA 1PE4A 2E0HA 1ZVGA 2N2QA 1SN1A 2E3GA 1BK8A 4AAZA 2N2RA 4AB0A 1WMTA 2NY8X 1NH5A 2KBJA 4KYPA 2B3CA 1AHOA 1N4NA 1OZZA 2KJAA 3E7RL 1SNBA 1JZAA 1DJTA 2E3FA 2LY6A 1I2VA 1T7BA 2GL1A 2KGQA 1GPSA 2ATBA 2KBHA 2YBRC 2B68A 1ZUTA 1PTXA 1LQIA 1P0AA 1DQ7A 1LQQA 1SEGA 2KYQA 4AEIA 1NE5A 1C55A 1P00A 2M8BB 1WT7A 1KV0A 2KSKA 1C56A 1MYNA 1I2UA 1B3CA 2N66A 4CQKA 1CN2A 2LKBA 2NY9X 2YEOA 1ZU3A 2BRZA 1GPTA 1NRAA 1T1TA 2KPYA 1JXCA 2LJ7A 1AYJA 2N69A 2KBKA 1CHZA 1PX9A 1JZBA 1BMRA 1FH3A 1BCGA
chains in the Genus database with same CATH superfamily
2MZ0A 1WWNA 3L4IA 5AQMA 1ATRA 5AR0A 1TI5A 2LJMA 2QWOA 1NGCA 4HHFA 3SF4D 2QWMA 5F0XA 2LI7A 3IUCA 2ASCA 5AQJA 5FPNA 1CN2A 1JKZA 2QWRA 1LQHA 3KP1A 4V1DC 4GNIA 1I6GA 1ZYVA 2KHOA 1BRZA 3PSMA 1KAXA 1ZFUA 2SN3A 3HSCA 1B7DA 1HX1A 1MR4A 1NPIA 1VNBA 1ZYWA 3A8YA 3KVGA 4UJ0A 1BA0A 1NRBA 2LY5A 1BUPA 4HE7A 3JXUA 5CY0A 5KK4A 4H5RA 3L56A 2LT8A 2YC1C 4H5NA 1OMYA 5AQPA 1ICAA 1ZVEA 4H5VA 5AQGA 3KC6A 3KP0A 3FZHA 3FZFA 1SN4A 2LR3A 5F2RA 2YILA 3FZKA 1I6FA 2I61A 3C7NA 3C7NB 4H5WA 1T7AA 1L4VA 3E7UX 1VNAA 2QW9A 2YIOA 5AQOA 1T7EA 1T0ZA 2MBKA 2BUPA 4HWIA 1NGGA 1PE4A 2A7TA 3KOZA 2E0HA 3KOYA 5AQZA 1NGIA 5AQLA 1ZVGA 3QFPA 1ATSA 3BK3C 2QWPA 2N2QA 3KHWA 1HJOA 5AQKA 5EY4A 1SN1A 2E3GA 2VY6A 3KOWA 5EX5A 5BPLA 1BK8A 2LN8A 4UAEF 3GDQA 3CW4A 3CQXA 3FZLA 4AAZA 1QQOA 2N2RA 4UADE 1POIA 4AB0A 5FPEA 1WMTA 2YIPA 2NY8X 3ATUA 1NH5A 2E88A 1NGHA 2KBJA 2B3CA 4KYPA 4H5TA 1AHOA 2QWQA 1N4NA 1OZZA 2KJAA 3E7RL 2E8AA 1YUWA 5AQYA 3LDPA 1SNBA 4UAFE 3GL1A 1NGEA 1JZAA 1DJTA 3D2EA 4FSVA 2E3FA 3D2EB 5AQXA 5BPMA 2LY6A 3KOXA 5FPDA 3FE1A 3R2VA 1I2VA 1T7BA 2GL1A 2KGQA 5AQNA 3D2FA 1GPSA 5AQHA 1NGAA 2ATBA 3D2FB 4KBOA 2KBHA 4IO8A 2YBRC 2B68A 1UGLA 1ZUTA 3GKUA 1PTXA 1LQIA 3QFUA 1P0AA 1DQ7A 1LQQA 2D56A 1BA1A 1QQMA 1SEGA 3ATVA 2KYQA 4AEIA 1KAZA 1NE5A 5AQSA 1P00A 1C55A 1K8BA 5EXWA 5AQTA 2M8BB 1WT7A 5AQWA 1NGJA 1KV0A 5AQIA 1NGDA 2KSKA 4FL9A 3LDNA 1C56A 1KAYA 1MYNA 5F1XA 1I2UA 2QWLA 2QWNA 3FZMA 1B3CA 2N66A 2V7ZA 3LDLA 4CQKA 5AQQA 5FPMA 3QI7A 2LKBA 1NGBA 1NGFA 2NY9X 2YEOA 3LDOA 1ZU3A 5AQVA 5BPNA 3I33A 2BRZA 2K35A 5BN8A 5AQUA 3AY9A 5AQRA 2JDQD 3L6QA 3QMLA 1GPTA 2GMOA 2G2KA 3LDQA 1QQNA 1NRAA 1T1TA 2KPYA 5EVZA 1JXCA 2LJ7A 1AYJA 1HPMA 1XRSB 2MN5A 2KBKA 1CHZA 1S3XA 2N69A 2QXLA 5AQFA 1PX9A 3M3ZA 5BN9A 1JZBA 2E2FA 1BMRA 1DKGD 1FH3A 1BCGA
chains in the Genus database with same CATH topology
2MZ0A 1WWNA 1TI5A 2LJMA 4HHFA 2LI7A 2ASCA 1JKZA 1LQHA 4V1DC 1I6GA 1ZYVA 1BRZA 3PSMA 1ZFUA 2SN3A 1B7DA 1MR4A 1NPIA 1VNBA 1ZYWA 4UJ0A 1NRBA 2LY5A 4HE7A 5CY0A 5KK4A 2LT8A 2YC1C 1OMYA 1ICAA 1ZVEA 1SN4A 2LR3A 1I6FA 2I61A 1T7AA 1L4VA 3E7UX 1VNAA 1T7EA 1T0ZA 2A7TA 1PE4A 2E0HA 1ZVGA 2N2QA 1SN1A 2E3GA 1BK8A 4AAZA 2N2RA 4AB0A 1WMTA 2NY8X 1NH5A 2KBJA 4KYPA 2B3CA 1AHOA 1N4NA 1OZZA 2KJAA 3E7RL 1SNBA 1JZAA 1DJTA 2E3FA 2LY6A 1I2VA 1T7BA 2GL1A 2KGQA 1GPSA 2ATBA 2KBHA 2YBRC 2B68A 1ZUTA 1PTXA 1LQIA 1P0AA 1DQ7A 1LQQA 1SEGA 2KYQA 4AEIA 1NE5A 1C55A 1P00A 2M8BB 1WT7A 1KV0A 2KSKA 1C56A 1MYNA 1I2UA 1B3CA 2N66A 4CQKA 1CN2A 2LKBA 2NY9X 2YEOA 1ZU3A 2BRZA 1GPTA 1NRAA 1T1TA 2KPYA 1JXCA 2LJ7A 1AYJA 2N69A 2KBKA 1CHZA 1PX9A 1JZBA 1BMRA 1FH3A 1BCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MZ0 A;  1WWN A;  1TI5 A;  2LJM A;  4HHF A;  2LI7 A;  2ASC A;  1JKZ A;  1LQH A;  4V1D C;  1I6G A;  1ZYV A;  1BRZ A;  3PSM A;  1ZFU A;  2SN3 A;  1B7D A;  1MR4 A;  1NPI A;  1VNB A;  1ZYW A;  4UJ0 A;  1NRB A;  2LY5 A;  4HE7 A;  5CY0 A;  5KK4 A;  2LT8 A;  2YC1 C;  1OMY A;  1ICA A;  1ZVE A;  1SN4 A;  2LR3 A;  1I6F A;  2I61 A;  1T7A A;  1L4V A;  3E7U X;  1VNA A;  1T7E A;  1T0Z A;  2A7T A;  1PE4 A;  2E0H A;  1ZVG A;  2N2Q A;  1SN1 A;  2E3G A;  1BK8 A;  4AAZ A;  2N2R A;  4AB0 A;  1WMT A;  2NY8 X;  1NH5 A;  2KBJ A;  4KYP A;  2B3C A;  1AHO A;  1N4N A;  1OZZ A;  2KJA A;  3E7R L;  1SNB A;  1JZA A;  1DJT A;  2E3F A;  2LY6 A;  1I2V A;  1T7B A;  2GL1 A;  2KGQ A;  1GPS A;  2ATB A;  2KBH A;  2YBR C;  2B68 A;  1ZUT A;  1PTX A;  1LQI A;  1P0A A;  1DQ7 A;  1LQQ A;  1SEG A;  2KYQ A;  4AEI A;  1NE5 A;  1C55 A;  1P00 A;  2M8B B;  1WT7 A;  1KV0 A;  2KSK A;  1C56 A;  1MYN A;  1I2U A;  1B3C A;  2N66 A;  4CQK A;  1CN2 A;  2LKB A;  2NY9 X;  2YEO A;  1ZU3 A;  2BRZ A;  1GPT A;  1NRA A;  1T1T A;  2KPY A;  1JXC A;  2LJ7 A;  1AYJ A;  2N69 A;  2KBK A;  1CHZ A;  1PX9 A;  1JZB A;  1BMR A;  1FH3 A;  1BCG A; 
#chains in the Genus database with same CATH topology
 2MZ0 A;  1WWN A;  3L4I A;  5AQM A;  1ATR A;  5AR0 A;  1TI5 A;  2LJM A;  2QWO A;  1NGC A;  4HHF A;  3SF4 D;  2QWM A;  5F0X A;  2LI7 A;  3IUC A;  2ASC A;  5AQJ A;  5FPN A;  1CN2 A;  1JKZ A;  2QWR A;  1LQH A;  3KP1 A;  4V1D C;  4GNI A;  1I6G A;  1ZYV A;  2KHO A;  1BRZ A;  3PSM A;  1KAX A;  1ZFU A;  2SN3 A;  3HSC A;  1B7D A;  1HX1 A;  1MR4 A;  1NPI A;  1VNB A;  1ZYW A;  3A8Y A;  3KVG A;  4UJ0 A;  1BA0 A;  1NRB A;  2LY5 A;  1BUP A;  4HE7 A;  3JXU A;  5CY0 A;  5KK4 A;  4H5R A;  3L56 A;  2LT8 A;  2YC1 C;  4H5N A;  1OMY A;  5AQP A;  1ICA A;  1ZVE A;  4H5V A;  5AQG A;  3KC6 A;  3KP0 A;  3FZH A;  3FZF A;  1SN4 A;  2LR3 A;  5F2R A;  2YIL A;  3FZK A;  1I6F A;  2I61 A;  3C7N A;  3C7N B;  4H5W A;  1T7A A;  1L4V A;  3E7U X;  1VNA A;  2QW9 A;  2YIO A;  5AQO A;  1T7E A;  1T0Z A;  2MBK A;  2BUP A;  4HWI A;  1NGG A;  1PE4 A;  2A7T A;  3KOZ A;  2E0H A;  3KOY A;  5AQZ A;  1NGI A;  5AQL A;  1ZVG A;  3QFP A;  1ATS A;  3BK3 C;  2QWP A;  2N2Q A;  3KHW A;  1HJO A;  5AQK A;  5EY4 A;  1SN1 A;  2E3G A;  2VY6 A;  3KOW A;  5EX5 A;  5BPL A;  1BK8 A;  2LN8 A;  4UAE F;  3GDQ A;  3CW4 A;  3CQX A;  3FZL A;  4AAZ A;  1QQO A;  2N2R A;  4UAD E;  1POI A;  4AB0 A;  5FPE A;  1WMT A;  2YIP A;  2NY8 X;  3ATU A;  1NH5 A;  2E88 A;  1NGH A;  2KBJ A;  2B3C A;  4KYP A;  4H5T A;  1AHO A;  2QWQ A;  1N4N A;  1OZZ A;  2KJA A;  3E7R L;  2E8A A;  1YUW A;  5AQY A;  3LDP A;  1SNB A;  4UAF E;  3GL1 A;  1NGE A;  1JZA A;  1DJT A;  3D2E A;  4FSV A;  2E3F A;  3D2E B;  5AQX A;  5BPM A;  2LY6 A;  3KOX A;  5FPD A;  3FE1 A;  3R2V A;  1I2V A;  1T7B A;  2GL1 A;  2KGQ A;  5AQN A;  3D2F A;  1GPS A;  5AQH A;  1NGA A;  2ATB A;  3D2F B;  4KBO A;  2KBH A;  4IO8 A;  2YBR C;  2B68 A;  1UGL A;  1ZUT A;  3GKU A;  1PTX A;  1LQI A;  3QFU A;  1P0A A;  1DQ7 A;  1LQQ A;  2D56 A;  1BA1 A;  1QQM A;  1SEG A;  3ATV A;  2KYQ A;  4AEI A;  1KAZ A;  1NE5 A;  5AQS A;  1P00 A;  1C55 A;  1K8B A;  5EXW A;  5AQT A;  2M8B B;  1WT7 A;  5AQW A;  1NGJ A;  1KV0 A;  5AQI A;  1NGD A;  2KSK A;  4FL9 A;  3LDN A;  1C56 A;  1KAY A;  1MYN A;  5F1X A;  1I2U A;  2QWL A;  2QWN A;  3FZM A;  1B3C A;  2N66 A;  2V7Z A;  3LDL A;  4CQK A;  5AQQ A;  5FPM A;  3QI7 A;  2LKB A;  1NGB A;  1NGF A;  2NY9 X;  2YEO A;  3LDO A;  1ZU3 A;  5AQV A;  5BPN A;  3I33 A;  2BRZ A;  2K35 A;  5BN8 A;  5AQU A;  3AY9 A;  5AQR A;  2JDQ D;  3L6Q A;  3QML A;  1GPT A;  2GMO A;  2G2K A;  3LDQ A;  1QQN A;  1NRA A;  1T1T A;  2KPY A;  5EVZ A;  1JXC A;  2LJ7 A;  1AYJ A;  1HPM A;  1XRS B;  2MN5 A;  2KBK A;  1CHZ A;  1S3X A;  2N69 A;  2QXL A;  5AQF A;  1PX9 A;  3M3Z A;  5BN9 A;  1JZB A;  2E2F A;  1BMR A;  1DKG D;  1FH3 A;  1BCG A; 
#chains in the Genus database with same CATH homology
 2MZ0 A;  1WWN A;  1TI5 A;  2LJM A;  4HHF A;  2LI7 A;  2ASC A;  1JKZ A;  1LQH A;  4V1D C;  1I6G A;  1ZYV A;  1BRZ A;  3PSM A;  1ZFU A;  2SN3 A;  1B7D A;  1MR4 A;  1NPI A;  1VNB A;  1ZYW A;  4UJ0 A;  1NRB A;  2LY5 A;  4HE7 A;  5CY0 A;  5KK4 A;  2LT8 A;  2YC1 C;  1OMY A;  1ICA A;  1ZVE A;  1SN4 A;  2LR3 A;  1I6F A;  2I61 A;  1T7A A;  1L4V A;  3E7U X;  1VNA A;  1T7E A;  1T0Z A;  2A7T A;  1PE4 A;  2E0H A;  1ZVG A;  2N2Q A;  1SN1 A;  2E3G A;  1BK8 A;  4AAZ A;  2N2R A;  4AB0 A;  1WMT A;  2NY8 X;  1NH5 A;  2KBJ A;  4KYP A;  2B3C A;  1AHO A;  1N4N A;  1OZZ A;  2KJA A;  3E7R L;  1SNB A;  1JZA A;  1DJT A;  2E3F A;  2LY6 A;  1I2V A;  1T7B A;  2GL1 A;  2KGQ A;  1GPS A;  2ATB A;  2KBH A;  2YBR C;  2B68 A;  1ZUT A;  1PTX A;  1LQI A;  1P0A A;  1DQ7 A;  1LQQ A;  1SEG A;  2KYQ A;  4AEI A;  1NE5 A;  1C55 A;  1P00 A;  2M8B B;  1WT7 A;  1KV0 A;  2KSK A;  1C56 A;  1MYN A;  1I2U A;  1B3C A;  2N66 A;  4CQK A;  1CN2 A;  2LKB A;  2NY9 X;  2YEO A;  1ZU3 A;  2BRZ A;  1GPT A;  1NRA A;  1T1T A;  2KPY A;  1JXC A;  2LJ7 A;  1AYJ A;  2N69 A;  2KBK A;  1CHZ A;  1PX9 A;  1JZB A;  1BMR A;  1FH3 A;  1BCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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