1T7BA

Crystal structure of mutant lys8gln of scorpion alpha-like neurotoxin bmk m1 from buthus martensii karsch
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
66
structure length
66
Chain Sequence
NSVRDAYIAQPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
pubmed doi rcsb
molecule keywords Alpha-like neurotoxin BmK-I
molecule tags Toxin
source organism Mesobuthus martensii
total genus 16
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2004-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1t7bA00
4AEIA 2KBKA 2LJMA 4HHFA 4AAZA 1NRBA 1GPSA 5CY0A 1LQQA 1C56A 1ZU3A 2KSKA 2KBHA 3E7UX 1LQIA 5KK4A 1DJTA 1ZYVA 2MZ0A 1JZBA 2M8BB 1CN2A 2N2QA 1P00A 1NPIA 1BK8A 2SN3A 1B7DA 1AHOA 2ASCA 2LY5A 2LR3A 3E7RL 1PE4A 1GPTA 2N69A 1I6FA 2E0HA 2NY8X 1MYNA 1AYJA 2I61A 1MR4A 1T7BA 1SEGA 2LY6A 4UJ0A 1T1TA 2YBRC 1PX9A 1B3CA 3PSMA 1TI5A 1NE5A 1NRAA 1PTXA 2GL1A 4CQKA 1I2UA 1WWNA 1WMTA 1OZZA 1CHZA 1SN1A 2LT8A 2YEOA 4KYPA 2N66A 1JXCA 2LKBA 1BRZA 1I2VA 1JZAA 1ZVEA 1JKZA 1NH5A 1ZFUA 1N4NA 2E3GA 1SNBA 2E3FA 2KGQA 1ZUTA 1SN4A 2LI7A 1VNBA 1C55A 2ATBA 2BRZA 4V1DC 2KYQA 1DQ7A 2B68A 4AB0A 1OMYA 2NY9X 2KBJA 1BMRA 2N2RA 1FH3A 1VNAA 2YC1C 4HE7A 1LQHA 2B3CA 1I6GA 1T7AA 1L4VA 2A7TA 2LJ7A 1KV0A 1WT7A 1P0AA 1ZYWA 2KPYA 2KJAA 1T7EA 1T0ZA 1ZVGA 1ICAA 1BCGA
chains in the Genus database with same CATH superfamily
1QQOA 2E88A 4AEIA 2E2FA 1NGFA 2KBKA 2LJMA 4HHFA 3FZHA 1NRBA 1HPMA 3FZLA 5AR0A 4AAZA 5CY0A 1GPSA 4UAEF 1LQQA 5AQLA 1C56A 3C7NA 1ATSA 3D2FA 3D2EA 5AQUA 2LN8A 1NGDA 1ZU3A 2KSKA 1POIA 2KBHA 3E7UX 1LQIA 3A8YA 3KP1A 5FPMA 1DJTA 1BA1A 2QWOA 5KK4A 2G2KA 1ZYVA 2BUPA 2K35A 2MZ0A 4H5NA 1JZBA 2M8BB 5AQQA 1CN2A 1NGAA 3GKUA 2QWRA 3FZMA 3JXUA 4HWIA 1UGLA 2N2QA 4FSVA 5AQMA 1P00A 2KHOA 5AQSA 2QWMA 1NPIA 2V7ZA 3AY9A 5AQTA 5EY4A 1NGEA 1BK8A 2SN3A 1B7DA 3KOWA 1KAZA 4IO8A 1AHOA 3ATUA 2ASCA 2LY5A 2LR3A 3E7RL 3KOXA 5AQIA 5BPNA 5FPDA 2JDQD 1PE4A 5AQHA 1GPTA 2N69A 3LDNA 4UAFE 1I6FA 2MBKA 1XRSB 2E0HA 2NY8X 1MYNA 1AYJA 4H5TA 1ATRA 2I61A 1MR4A 1T7BA 5AQNA 1SEGA 3I33A 5BN8A 3FZFA 2LY6A 3HSCA 5BPLA 5AQXA 4UJ0A 1T1TA 2YBRC 1PX9A 3C7NB 3D2EB 3QI7A 3CQXA 5EVZA 3PSMA 1B3CA 3BK3C 1KAXA 3QMLA 1TI5A 1BUPA 3SF4D 1NE5A 1NRAA 3QFUA 1NGIA 1PTXA 2QWNA 2QWLA 3CW4A 2GL1A 3ATVA 4CQKA 1NGGA 1DKGD 2QXLA 4UADE 3LDOA 1I2UA 5AQPA 5F0XA 1WWNA 5AQOA 1QQMA 2YIOA 1WMTA 1OZZA 2D56A 4H5WA 1KAYA 2YILA 3GL1A 1QQNA 1CHZA 3KHWA 3LDPA 3QFPA 5AQJA 5BPMA 4H5VA 1SN1A 1BA0A 1NGJA 2LT8A 2YEOA 5FPNA 5AQYA 4KYPA 2MN5A 2N66A 3KP0A 5FPEA 4FL9A 1JXCA 3KOYA 5AQKA 2LKBA 1BRZA 5AQWA 1I2VA 1JZAA 1NGHA 1ZVEA 2QW9A 5AQZA 1JKZA 1NH5A 1ZFUA 3D2FB 3M3ZA 3FE1A 1N4NA 3L6QA 2E3GA 1SNBA 2E3FA 1NGCA 2KGQA 2VY6A 1ZUTA 1SN4A 2LI7A 1VNBA 5F1XA 1C55A 2QWPA 5EX5A 2ATBA 2QWQA 1S3XA 2YIPA 3IUCA 3L4IA 5AQRA 2BRZA 4V1DC 2KYQA 1DQ7A 2B68A 5AQVA 4AB0A 3FZKA 5AQGA 4KBOA 1OMYA 5EXWA 3L56A 2NY9X 2KBJA 1BMRA 5BN9A 3KOZA 2GMOA 3KC6A 2N2RA 3GDQA 3LDQA 1FH3A 1VNAA 2YC1C 4H5RA 4HE7A 1LQHA 2B3CA 1I6GA 1T7AA 5AQFA 2E8AA 1L4VA 5F2RA 1YUWA 2A7TA 2LJ7A 1HJOA 1KV0A 1WT7A 1P0AA 1ZYWA 1HX1A 3KVGA 2KPYA 3LDLA 2KJAA 3R2VA 1T7EA 1K8BA 1NGBA 1T0ZA 1ZVGA 1ICAA 4GNIA 1BCGA
chains in the Genus database with same CATH topology
4AEIA 2KBKA 2LJMA 4HHFA 4AAZA 1NRBA 1GPSA 5CY0A 1LQQA 1C56A 1ZU3A 2KSKA 2KBHA 3E7UX 1LQIA 5KK4A 1DJTA 1ZYVA 2MZ0A 1JZBA 2M8BB 1CN2A 2N2QA 1P00A 1NPIA 1BK8A 2SN3A 1B7DA 1AHOA 2ASCA 2LY5A 2LR3A 3E7RL 1PE4A 1GPTA 2N69A 1I6FA 2E0HA 2NY8X 1MYNA 1AYJA 2I61A 1MR4A 1T7BA 1SEGA 2LY6A 4UJ0A 1T1TA 2YBRC 1PX9A 1B3CA 3PSMA 1TI5A 1NE5A 1NRAA 1PTXA 2GL1A 4CQKA 1I2UA 1WWNA 1WMTA 1OZZA 1CHZA 1SN1A 2LT8A 2YEOA 4KYPA 2N66A 1JXCA 2LKBA 1BRZA 1I2VA 1JZAA 1ZVEA 1JKZA 1NH5A 1ZFUA 1N4NA 2E3GA 1SNBA 2E3FA 2KGQA 1ZUTA 1SN4A 2LI7A 1VNBA 1C55A 2ATBA 2BRZA 4V1DC 2KYQA 1DQ7A 2B68A 4AB0A 1OMYA 2NY9X 2KBJA 1BMRA 2N2RA 1FH3A 1VNAA 2YC1C 4HE7A 1LQHA 2B3CA 1I6GA 1T7AA 1L4VA 2A7TA 2LJ7A 1KV0A 1WT7A 1P0AA 1ZYWA 2KPYA 2KJAA 1T7EA 1T0ZA 1ZVGA 1ICAA 1BCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AEI A;  2KBK A;  2LJM A;  4HHF A;  4AAZ A;  1NRB A;  1GPS A;  5CY0 A;  1LQQ A;  1C56 A;  1ZU3 A;  2KSK A;  2KBH A;  3E7U X;  1LQI A;  5KK4 A;  1DJT A;  1ZYV A;  2MZ0 A;  1JZB A;  2M8B B;  1CN2 A;  2N2Q A;  1P00 A;  1NPI A;  1BK8 A;  2SN3 A;  1B7D A;  1AHO A;  2ASC A;  2LY5 A;  2LR3 A;  3E7R L;  1PE4 A;  1GPT A;  2N69 A;  1I6F A;  2E0H A;  2NY8 X;  1MYN A;  1AYJ A;  2I61 A;  1MR4 A;  1T7B A;  1SEG A;  2LY6 A;  4UJ0 A;  1T1T A;  2YBR C;  1PX9 A;  1B3C A;  3PSM A;  1TI5 A;  1NE5 A;  1NRA A;  1PTX A;  2GL1 A;  4CQK A;  1I2U A;  1WWN A;  1WMT A;  1OZZ A;  1CHZ A;  1SN1 A;  2LT8 A;  2YEO A;  4KYP A;  2N66 A;  1JXC A;  2LKB A;  1BRZ A;  1I2V A;  1JZA A;  1ZVE A;  1JKZ A;  1NH5 A;  1ZFU A;  1N4N A;  2E3G A;  1SNB A;  2E3F A;  2KGQ A;  1ZUT A;  1SN4 A;  2LI7 A;  1VNB A;  1C55 A;  2ATB A;  2BRZ A;  4V1D C;  2KYQ A;  1DQ7 A;  2B68 A;  4AB0 A;  1OMY A;  2NY9 X;  2KBJ A;  1BMR A;  2N2R A;  1FH3 A;  1VNA A;  2YC1 C;  4HE7 A;  1LQH A;  2B3C A;  1I6G A;  1T7A A;  1L4V A;  2A7T A;  2LJ7 A;  1KV0 A;  1WT7 A;  1P0A A;  1ZYW A;  2KPY A;  2KJA A;  1T7E A;  1T0Z A;  1ZVG A;  1ICA A;  1BCG A; 
#chains in the Genus database with same CATH topology
 1QQO A;  2E88 A;  4AEI A;  2E2F A;  1NGF A;  2KBK A;  2LJM A;  4HHF A;  3FZH A;  1NRB A;  1HPM A;  3FZL A;  5AR0 A;  4AAZ A;  5CY0 A;  1GPS A;  4UAE F;  1LQQ A;  5AQL A;  1C56 A;  3C7N A;  1ATS A;  3D2F A;  3D2E A;  5AQU A;  2LN8 A;  1NGD A;  1ZU3 A;  2KSK A;  1POI A;  2KBH A;  3E7U X;  1LQI A;  3A8Y A;  3KP1 A;  5FPM A;  1DJT A;  1BA1 A;  2QWO A;  5KK4 A;  2G2K A;  1ZYV A;  2BUP A;  2K35 A;  2MZ0 A;  4H5N A;  1JZB A;  2M8B B;  5AQQ A;  1CN2 A;  1NGA A;  3GKU A;  2QWR A;  3FZM A;  3JXU A;  4HWI A;  1UGL A;  2N2Q A;  4FSV A;  5AQM A;  1P00 A;  2KHO A;  5AQS A;  2QWM A;  1NPI A;  2V7Z A;  3AY9 A;  5AQT A;  5EY4 A;  1NGE A;  1BK8 A;  2SN3 A;  1B7D A;  3KOW A;  1KAZ A;  4IO8 A;  1AHO A;  3ATU A;  2ASC A;  2LY5 A;  2LR3 A;  3E7R L;  3KOX A;  5AQI A;  5BPN A;  5FPD A;  2JDQ D;  1PE4 A;  5AQH A;  1GPT A;  2N69 A;  3LDN A;  4UAF E;  1I6F A;  2MBK A;  1XRS B;  2E0H A;  2NY8 X;  1MYN A;  1AYJ A;  4H5T A;  1ATR A;  2I61 A;  1MR4 A;  1T7B A;  5AQN A;  1SEG A;  3I33 A;  5BN8 A;  3FZF A;  2LY6 A;  3HSC A;  5BPL A;  5AQX A;  4UJ0 A;  1T1T A;  2YBR C;  1PX9 A;  3C7N B;  3D2E B;  3QI7 A;  3CQX A;  5EVZ A;  3PSM A;  1B3C A;  3BK3 C;  1KAX A;  3QML A;  1TI5 A;  1BUP A;  3SF4 D;  1NE5 A;  1NRA A;  3QFU A;  1NGI A;  1PTX A;  2QWN A;  2QWL A;  3CW4 A;  2GL1 A;  3ATV A;  4CQK A;  1NGG A;  1DKG D;  2QXL A;  4UAD E;  3LDO A;  1I2U A;  5AQP A;  5F0X A;  1WWN A;  5AQO A;  1QQM A;  2YIO A;  1WMT A;  1OZZ A;  2D56 A;  4H5W A;  1KAY A;  2YIL A;  3GL1 A;  1QQN A;  1CHZ A;  3KHW A;  3LDP A;  3QFP A;  5AQJ A;  5BPM A;  4H5V A;  1SN1 A;  1BA0 A;  1NGJ A;  2LT8 A;  2YEO A;  5FPN A;  5AQY A;  4KYP A;  2MN5 A;  2N66 A;  3KP0 A;  5FPE A;  4FL9 A;  1JXC A;  3KOY A;  5AQK A;  2LKB A;  1BRZ A;  5AQW A;  1I2V A;  1JZA A;  1NGH A;  1ZVE A;  2QW9 A;  5AQZ A;  1JKZ A;  1NH5 A;  1ZFU A;  3D2F B;  3M3Z A;  3FE1 A;  1N4N A;  3L6Q A;  2E3G A;  1SNB A;  2E3F A;  1NGC A;  2KGQ A;  2VY6 A;  1ZUT A;  1SN4 A;  2LI7 A;  1VNB A;  5F1X A;  1C55 A;  2QWP A;  5EX5 A;  2ATB A;  2QWQ A;  1S3X A;  2YIP A;  3IUC A;  3L4I A;  5AQR A;  2BRZ A;  4V1D C;  2KYQ A;  1DQ7 A;  2B68 A;  5AQV A;  4AB0 A;  3FZK A;  5AQG A;  4KBO A;  1OMY A;  5EXW A;  3L56 A;  2NY9 X;  2KBJ A;  1BMR A;  5BN9 A;  3KOZ A;  2GMO A;  3KC6 A;  2N2R A;  3GDQ A;  3LDQ A;  1FH3 A;  1VNA A;  2YC1 C;  4H5R A;  4HE7 A;  1LQH A;  2B3C A;  1I6G A;  1T7A A;  5AQF A;  2E8A A;  1L4V A;  5F2R A;  1YUW A;  2A7T A;  2LJ7 A;  1HJO A;  1KV0 A;  1WT7 A;  1P0A A;  1ZYW A;  1HX1 A;  3KVG A;  2KPY A;  3LDL A;  2KJA A;  3R2V A;  1T7E A;  1K8B A;  1NGB A;  1T0Z A;  1ZVG A;  1ICA A;  4GNI A;  1BCG A; 
#chains in the Genus database with same CATH homology
 4AEI A;  2KBK A;  2LJM A;  4HHF A;  4AAZ A;  1NRB A;  1GPS A;  5CY0 A;  1LQQ A;  1C56 A;  1ZU3 A;  2KSK A;  2KBH A;  3E7U X;  1LQI A;  5KK4 A;  1DJT A;  1ZYV A;  2MZ0 A;  1JZB A;  2M8B B;  1CN2 A;  2N2Q A;  1P00 A;  1NPI A;  1BK8 A;  2SN3 A;  1B7D A;  1AHO A;  2ASC A;  2LY5 A;  2LR3 A;  3E7R L;  1PE4 A;  1GPT A;  2N69 A;  1I6F A;  2E0H A;  2NY8 X;  1MYN A;  1AYJ A;  2I61 A;  1MR4 A;  1T7B A;  1SEG A;  2LY6 A;  4UJ0 A;  1T1T A;  2YBR C;  1PX9 A;  1B3C A;  3PSM A;  1TI5 A;  1NE5 A;  1NRA A;  1PTX A;  2GL1 A;  4CQK A;  1I2U A;  1WWN A;  1WMT A;  1OZZ A;  1CHZ A;  1SN1 A;  2LT8 A;  2YEO A;  4KYP A;  2N66 A;  1JXC A;  2LKB A;  1BRZ A;  1I2V A;  1JZA A;  1ZVE A;  1JKZ A;  1NH5 A;  1ZFU A;  1N4N A;  2E3G A;  1SNB A;  2E3F A;  2KGQ A;  1ZUT A;  1SN4 A;  2LI7 A;  1VNB A;  1C55 A;  2ATB A;  2BRZ A;  4V1D C;  2KYQ A;  1DQ7 A;  2B68 A;  4AB0 A;  1OMY A;  2NY9 X;  2KBJ A;  1BMR A;  2N2R A;  1FH3 A;  1VNA A;  2YC1 C;  4HE7 A;  1LQH A;  2B3C A;  1I6G A;  1T7A A;  1L4V A;  2A7T A;  2LJ7 A;  1KV0 A;  1WT7 A;  1P0A A;  1ZYW A;  2KPY A;  2KJA A;  1T7E A;  1T0Z A;  1ZVG A;  1ICA A;  1BCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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