1SEGA

Crystal structure of a toxin chimera between lqh-alpha-it from the scorpion leiurus quinquestriatus hebraeus and aah2 from androctonus australis hector
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
64
structure length
64
Chain Sequence
VKDGYIVKNYNCTYFCFRNAYCNEECTKLKGESGYCQWASPYGNACYCYKLPDHVPIRVPGKCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of the high insecticidal potency of scorpion alpha-toxins.
pubmed doi rcsb
molecule keywords AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN
molecule tags Toxin
source organism Androctonus australis hector
total genus 17
structure length 64
sequence length 64
ec nomenclature
pdb deposition date 2004-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1segA00
1T7BA 2E3GA 1OZZA 1B3CA 1DJTA 1T1TA 2KPYA 4UJ0A 4HHFA 2E3FA 1I6FA 1C55A 4CQKA 1NRBA 2LR3A 1NE5A 2ASCA 1SEGA 1L4VA 2NY9X 1BRZA 1ZVGA 2LI7A 2YBRC 2B3CA 2NY8X 1JXCA 2YC1C 1B7DA 1N4NA 1SN4A 1WMTA 2KSKA 2MZ0A 2LY6A 1I2UA 3E7UX 1AHOA 1T7EA 1WT7A 1SNBA 1LQHA 1T0ZA 1JZBA 1JZAA 1PTXA 1AYJA 1ICAA 2LT8A 1JKZA 1VNAA 2A7TA 2KGQA 2LJMA 1VNBA 3E7RL 2ATBA 4V1DC 1CHZA 1NH5A 1I6GA 2SN3A 1P00A 2GL1A 2N69A 1TI5A 2M8BB 4HE7A 4KYPA 1CN2A 2B68A 2I61A 1ZVEA 1BCGA 1KV0A 1GPTA 5KK4A 1ZFUA 4AEIA 1P0AA 1SN1A 1BK8A 1ZU3A 2KBHA 4AB0A 4AAZA 2LY5A 1ZYWA 1OMYA 2E0HA 1DQ7A 1BMRA 1MYNA 2N2RA 2KBJA 2N2QA 1LQIA 2KYQA 1ZYVA 2BRZA 1NRAA 2N66A 1LQQA 2LJ7A 1I2VA 1C56A 1NPIA 2KJAA 1PX9A 1PE4A 2YEOA 1ZUTA 3PSMA 1GPSA 5CY0A 1FH3A 1WWNA 2KBKA 2LKBA 1MR4A 1T7AA
chains in the Genus database with same CATH superfamily
4FSVA 3C7NB 1KAYA 1POIA 1T7BA 2E88A 3D2FA 1DKGD 3A8YA 2MN5A 5EXWA 2E3GA 1OZZA 1NGCA 2K35A 1B3CA 4UAEF 5AQYA 1DJTA 5F2RA 1NGJA 3FZHA 1T1TA 2KPYA 2QWNA 3M3ZA 4IO8A 4HHFA 4UJ0A 2E3FA 1I6FA 1NGGA 1C55A 5BPLA 4CQKA 3ATVA 3FZLA 1NRBA 5AQZA 2LR3A 1BA1A 3LDNA 1NE5A 2V7ZA 4KBOA 2ASCA 1UGLA 4H5NA 1SEGA 1L4VA 2NY9X 3SF4D 4GNIA 1BRZA 3I33A 1ZVGA 1BA0A 2LI7A 4H5TA 1K8BA 1BUPA 2VY6A 2YBRC 2YIPA 3FZKA 2YIOA 3KOWA 2B3CA 5AQVA 5AQWA 5FPEA 1QQOA 2NY8X 2G2KA 1JXCA 1KAXA 2YC1C 5F0XA 1B7DA 3KVGA 1N4NA 1SN4A 1WMTA 2KSKA 2MZ0A 3L56A 3QFPA 3QI7A 5AR0A 1NGBA 3HSCA 2LY6A 3KP0A 3IUCA 5AQPA 3E7UX 1I2UA 2MBKA 1AHOA 1T7EA 1WT7A 1SNBA 1LQHA 1T0ZA 1JZBA 3KOYA 5BN9A 2E2FA 5BPNA 1JZAA 3KP1A 1PTXA 3R2VA 3LDPA 1AYJA 1ICAA 3LDOA 5AQJA 5AQIA 2LT8A 2QW9A 4H5RA 5FPNA 1VNAA 2A7TA 1JKZA 1ATSA 2YILA 2KGQA 3GKUA 1KAZA 2LJMA 1NGEA 1VNBA 1XRSB 3E7RL 3GDQA 2ATBA 3AY9A 2JDQD 4V1DC 1CHZA 1HJOA 1NH5A 5AQKA 1NGHA 2LN8A 1I6GA 1NGAA 2QWPA 2SN3A 5AQMA 5AQGA 4UADE 1P00A 3ATUA 3BK3C 2QWQA 2BUPA 5BPMA 2GL1A 5EY4A 3C7NA 3D2FB 5AQHA 2N69A 1S3XA 3L4IA 1TI5A 2M8BB 5FPDA 4HE7A 4KYPA 3KOZA 1CN2A 1NGFA 2B68A 2I61A 1ZVEA 5F1XA 1BCGA 1KV0A 1GPTA 5KK4A 5AQTA 1ZFUA 3FZMA 5EX5A 4H5VA 4AEIA 2QWMA 5FPMA 1P0AA 1SN1A 3FZFA 2GMOA 3KC6A 2D56A 3KOXA 4UAFE 3D2EB 2KHOA 5AQNA 5AQQA 5AQUA 1BK8A 1ZU3A 2KBHA 1HX1A 4AB0A 4AAZA 2LY5A 1ZYWA 1OMYA 2E0HA 1DQ7A 1YUWA 1BMRA 1MYNA 2N2RA 2KBJA 2N2QA 5AQRA 1LQIA 2KYQA 3JXUA 3KHWA 1ZYVA 2BRZA 2QXLA 1NRAA 2QWLA 3L6QA 1NGIA 1QQNA 2N66A 1LQQA 5EVZA 2LJ7A 3CW4A 1I2VA 3QMLA 5AQLA 5AQFA 1C56A 1NPIA 2KJAA 1PX9A 3FE1A 5AQOA 1ATRA 1PE4A 2E8AA 3QFUA 5AQSA 2YEOA 3D2EA 3GL1A 1ZUTA 1NGDA 2QWRA 3PSMA 1GPSA 3CQXA 4HWIA 5CY0A 3LDQA 5BN8A 1FH3A 1QQMA 3LDLA 2QWOA 4H5WA 4FL9A 1HPMA 1WWNA 5AQXA 2KBKA 2LKBA 1MR4A 1T7AA
chains in the Genus database with same CATH topology
1T7BA 2E3GA 1OZZA 1B3CA 1DJTA 1T1TA 2KPYA 4UJ0A 4HHFA 2E3FA 1I6FA 1C55A 4CQKA 1NRBA 2LR3A 1NE5A 2ASCA 1SEGA 1L4VA 2NY9X 1BRZA 1ZVGA 2LI7A 2YBRC 2B3CA 2NY8X 1JXCA 2YC1C 1B7DA 1N4NA 1SN4A 1WMTA 2KSKA 2MZ0A 2LY6A 1I2UA 3E7UX 1AHOA 1T7EA 1WT7A 1SNBA 1LQHA 1T0ZA 1JZBA 1JZAA 1PTXA 1AYJA 1ICAA 2LT8A 1JKZA 1VNAA 2A7TA 2KGQA 2LJMA 1VNBA 3E7RL 2ATBA 4V1DC 1CHZA 1NH5A 1I6GA 2SN3A 1P00A 2GL1A 2N69A 1TI5A 2M8BB 4HE7A 4KYPA 1CN2A 2B68A 2I61A 1ZVEA 1BCGA 1KV0A 1GPTA 5KK4A 1ZFUA 4AEIA 1P0AA 1SN1A 1BK8A 1ZU3A 2KBHA 4AB0A 4AAZA 2LY5A 1ZYWA 1OMYA 2E0HA 1DQ7A 1BMRA 1MYNA 2N2RA 2KBJA 2N2QA 1LQIA 2KYQA 1ZYVA 2BRZA 1NRAA 2N66A 1LQQA 2LJ7A 1I2VA 1C56A 1NPIA 2KJAA 1PX9A 1PE4A 2YEOA 1ZUTA 3PSMA 1GPSA 5CY0A 1FH3A 1WWNA 2KBKA 2LKBA 1MR4A 1T7AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T7B A;  2E3G A;  1OZZ A;  1B3C A;  1DJT A;  1T1T A;  2KPY A;  4UJ0 A;  4HHF A;  2E3F A;  1I6F A;  1C55 A;  4CQK A;  1NRB A;  2LR3 A;  1NE5 A;  2ASC A;  1SEG A;  1L4V A;  2NY9 X;  1BRZ A;  1ZVG A;  2LI7 A;  2YBR C;  2B3C A;  2NY8 X;  1JXC A;  2YC1 C;  1B7D A;  1N4N A;  1SN4 A;  1WMT A;  2KSK A;  2MZ0 A;  2LY6 A;  1I2U A;  3E7U X;  1AHO A;  1T7E A;  1WT7 A;  1SNB A;  1LQH A;  1T0Z A;  1JZB A;  1JZA A;  1PTX A;  1AYJ A;  1ICA A;  2LT8 A;  1JKZ A;  1VNA A;  2A7T A;  2KGQ A;  2LJM A;  1VNB A;  3E7R L;  2ATB A;  4V1D C;  1CHZ A;  1NH5 A;  1I6G A;  2SN3 A;  1P00 A;  2GL1 A;  2N69 A;  1TI5 A;  2M8B B;  4HE7 A;  4KYP A;  1CN2 A;  2B68 A;  2I61 A;  1ZVE A;  1BCG A;  1KV0 A;  1GPT A;  5KK4 A;  1ZFU A;  4AEI A;  1P0A A;  1SN1 A;  1BK8 A;  1ZU3 A;  2KBH A;  4AB0 A;  4AAZ A;  2LY5 A;  1ZYW A;  1OMY A;  2E0H A;  1DQ7 A;  1BMR A;  1MYN A;  2N2R A;  2KBJ A;  2N2Q A;  1LQI A;  2KYQ A;  1ZYV A;  2BRZ A;  1NRA A;  2N66 A;  1LQQ A;  2LJ7 A;  1I2V A;  1C56 A;  1NPI A;  2KJA A;  1PX9 A;  1PE4 A;  2YEO A;  1ZUT A;  3PSM A;  1GPS A;  5CY0 A;  1FH3 A;  1WWN A;  2KBK A;  2LKB A;  1MR4 A;  1T7A A; 
#chains in the Genus database with same CATH topology
 4FSV A;  3C7N B;  1KAY A;  1POI A;  1T7B A;  2E88 A;  3D2F A;  1DKG D;  3A8Y A;  2MN5 A;  5EXW A;  2E3G A;  1OZZ A;  1NGC A;  2K35 A;  1B3C A;  4UAE F;  5AQY A;  1DJT A;  5F2R A;  1NGJ A;  3FZH A;  1T1T A;  2KPY A;  2QWN A;  3M3Z A;  4IO8 A;  4HHF A;  4UJ0 A;  2E3F A;  1I6F A;  1NGG A;  1C55 A;  5BPL A;  4CQK A;  3ATV A;  3FZL A;  1NRB A;  5AQZ A;  2LR3 A;  1BA1 A;  3LDN A;  1NE5 A;  2V7Z A;  4KBO A;  2ASC A;  1UGL A;  4H5N A;  1SEG A;  1L4V A;  2NY9 X;  3SF4 D;  4GNI A;  1BRZ A;  3I33 A;  1ZVG A;  1BA0 A;  2LI7 A;  4H5T A;  1K8B A;  1BUP A;  2VY6 A;  2YBR C;  2YIP A;  3FZK A;  2YIO A;  3KOW A;  2B3C A;  5AQV A;  5AQW A;  5FPE A;  1QQO A;  2NY8 X;  2G2K A;  1JXC A;  1KAX A;  2YC1 C;  5F0X A;  1B7D A;  3KVG A;  1N4N A;  1SN4 A;  1WMT A;  2KSK A;  2MZ0 A;  3L56 A;  3QFP A;  3QI7 A;  5AR0 A;  1NGB A;  3HSC A;  2LY6 A;  3KP0 A;  3IUC A;  5AQP A;  3E7U X;  1I2U A;  2MBK A;  1AHO A;  1T7E A;  1WT7 A;  1SNB A;  1LQH A;  1T0Z A;  1JZB A;  3KOY A;  5BN9 A;  2E2F A;  5BPN A;  1JZA A;  3KP1 A;  1PTX A;  3R2V A;  3LDP A;  1AYJ A;  1ICA A;  3LDO A;  5AQJ A;  5AQI A;  2LT8 A;  2QW9 A;  4H5R A;  5FPN A;  1VNA A;  2A7T A;  1JKZ A;  1ATS A;  2YIL A;  2KGQ A;  3GKU A;  1KAZ A;  2LJM A;  1NGE A;  1VNB A;  1XRS B;  3E7R L;  3GDQ A;  2ATB A;  3AY9 A;  2JDQ D;  4V1D C;  1CHZ A;  1HJO A;  1NH5 A;  5AQK A;  1NGH A;  2LN8 A;  1I6G A;  1NGA A;  2QWP A;  2SN3 A;  5AQM A;  5AQG A;  4UAD E;  1P00 A;  3ATU A;  3BK3 C;  2QWQ A;  2BUP A;  5BPM A;  2GL1 A;  5EY4 A;  3C7N A;  3D2F B;  5AQH A;  2N69 A;  1S3X A;  3L4I A;  1TI5 A;  2M8B B;  5FPD A;  4HE7 A;  4KYP A;  3KOZ A;  1CN2 A;  1NGF A;  2B68 A;  2I61 A;  1ZVE A;  5F1X A;  1BCG A;  1KV0 A;  1GPT A;  5KK4 A;  5AQT A;  1ZFU A;  3FZM A;  5EX5 A;  4H5V A;  4AEI A;  2QWM A;  5FPM A;  1P0A A;  1SN1 A;  3FZF A;  2GMO A;  3KC6 A;  2D56 A;  3KOX A;  4UAF E;  3D2E B;  2KHO A;  5AQN A;  5AQQ A;  5AQU A;  1BK8 A;  1ZU3 A;  2KBH A;  1HX1 A;  4AB0 A;  4AAZ A;  2LY5 A;  1ZYW A;  1OMY A;  2E0H A;  1DQ7 A;  1YUW A;  1BMR A;  1MYN A;  2N2R A;  2KBJ A;  2N2Q A;  5AQR A;  1LQI A;  2KYQ A;  3JXU A;  3KHW A;  1ZYV A;  2BRZ A;  2QXL A;  1NRA A;  2QWL A;  3L6Q A;  1NGI A;  1QQN A;  2N66 A;  1LQQ A;  5EVZ A;  2LJ7 A;  3CW4 A;  1I2V A;  3QML A;  5AQL A;  5AQF A;  1C56 A;  1NPI A;  2KJA A;  1PX9 A;  3FE1 A;  5AQO A;  1ATR A;  1PE4 A;  2E8A A;  3QFU A;  5AQS A;  2YEO A;  3D2E A;  3GL1 A;  1ZUT A;  1NGD A;  2QWR A;  3PSM A;  1GPS A;  3CQX A;  4HWI A;  5CY0 A;  3LDQ A;  5BN8 A;  1FH3 A;  1QQM A;  3LDL A;  2QWO A;  4H5W A;  4FL9 A;  1HPM A;  1WWN A;  5AQX A;  2KBK A;  2LKB A;  1MR4 A;  1T7A A; 
#chains in the Genus database with same CATH homology
 1T7B A;  2E3G A;  1OZZ A;  1B3C A;  1DJT A;  1T1T A;  2KPY A;  4UJ0 A;  4HHF A;  2E3F A;  1I6F A;  1C55 A;  4CQK A;  1NRB A;  2LR3 A;  1NE5 A;  2ASC A;  1SEG A;  1L4V A;  2NY9 X;  1BRZ A;  1ZVG A;  2LI7 A;  2YBR C;  2B3C A;  2NY8 X;  1JXC A;  2YC1 C;  1B7D A;  1N4N A;  1SN4 A;  1WMT A;  2KSK A;  2MZ0 A;  2LY6 A;  1I2U A;  3E7U X;  1AHO A;  1T7E A;  1WT7 A;  1SNB A;  1LQH A;  1T0Z A;  1JZB A;  1JZA A;  1PTX A;  1AYJ A;  1ICA A;  2LT8 A;  1JKZ A;  1VNA A;  2A7T A;  2KGQ A;  2LJM A;  1VNB A;  3E7R L;  2ATB A;  4V1D C;  1CHZ A;  1NH5 A;  1I6G A;  2SN3 A;  1P00 A;  2GL1 A;  2N69 A;  1TI5 A;  2M8B B;  4HE7 A;  4KYP A;  1CN2 A;  2B68 A;  2I61 A;  1ZVE A;  1BCG A;  1KV0 A;  1GPT A;  5KK4 A;  1ZFU A;  4AEI A;  1P0A A;  1SN1 A;  1BK8 A;  1ZU3 A;  2KBH A;  4AB0 A;  4AAZ A;  2LY5 A;  1ZYW A;  1OMY A;  2E0H A;  1DQ7 A;  1BMR A;  1MYN A;  2N2R A;  2KBJ A;  2N2Q A;  1LQI A;  2KYQ A;  1ZYV A;  2BRZ A;  1NRA A;  2N66 A;  1LQQ A;  2LJ7 A;  1I2V A;  1C56 A;  1NPI A;  2KJA A;  1PX9 A;  1PE4 A;  2YEO A;  1ZUT A;  3PSM A;  1GPS A;  5CY0 A;  1FH3 A;  1WWN A;  2KBK A;  2LKB A;  1MR4 A;  1T7A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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