5KK4A

Crystal structure of the plant defensin nsd7 bound to phosphatidic acid
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
47
structure length
47
Chain Sequence
KDCKRESNTFPGICITKPPCRKACIREKFTDGHCSKILRRCLCTKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Nicotiana suaveolens x nicotiana tabacum
molecule keywords NsD7
total genus 12
structure length 47
sequence length 47
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2016-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00304 Gamma-thionin Gamma-thionin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 5kk4A00
2ASCA 2E0HA 1I6GA 1SEGA 1C55A 5KK4A 1PTXA 2GL1A 3E7RL 4V1DC 1T7AA 2E3FA 4HE7A 1N4NA 1P00A 1DJTA 1SN4A 2N2RA 1VNAA 1NPIA 1ICAA 2N2QA 4AB0A 1LQQA 2KJAA 1ZFUA 1ZUTA 1B7DA 2KYQA 1SN1A 2YC1C 2YBRC 3PSMA 1WWNA 2N66A 1BK8A 2LY6A 1I2VA 2LR3A 2MZ0A 1WT7A 2SN3A 2BRZA 1TI5A 4HHFA 1NE5A 1KV0A 2KPYA 2A7TA 1JKZA 1ZYWA 2N69A 1MYNA 2M8BB 1BCGA 2NY8X 1C56A 1T7BA 1GPSA 1OMYA 1P0AA 1LQHA 2LJ7A 4UJ0A 1CN2A 2KBJA 2LT8A 1NRBA 2KBHA 2KBKA 2KSKA 1CHZA 2YEOA 2E3GA 2NY9X 1L4VA 2LKBA 1LQIA 1BMRA 1ZYVA 1DQ7A 1SNBA 1ZVEA 1GPTA 1JZBA 2I61A 1PE4A 1B3CA 1VNBA 1AYJA 4KYPA 5CY0A 2LI7A 1PX9A 1AHOA 1I6FA 1T1TA 1ZU3A 1NRAA 2KGQA 1FH3A 2LY5A 1I2UA 1BRZA 4AAZA 1ZVGA 3E7UX 1JZAA 1WMTA 2ATBA 1MR4A 1OZZA 1T0ZA 4AEIA 2B3CA 2LJMA 1NH5A 1JXCA 1T7EA 2B68A 4CQKA
chains in the Genus database with same CATH superfamily
2ASCA 2E0HA 1I6GA 5BN9A 2QWRA 1SEGA 1QQNA 5KK4A 3KHWA 1C55A 1ATSA 1PTXA 3HSCA 2GL1A 3E7RL 3FE1A 4V1DC 5FPDA 1T7AA 5EY4A 2E3FA 2E2FA 4HE7A 5F0XA 1N4NA 1P00A 1DJTA 1SN4A 2E8AA 2N2RA 3QMLA 3KP0A 1POIA 3QFPA 1VNAA 5AQVA 3KOXA 2QXLA 3SF4D 5AQPA 1HX1A 2QWPA 5AQWA 3ATVA 1NPIA 4H5NA 1KAXA 1CN2A 3LDNA 1ICAA 1UGLA 2N2QA 4AB0A 1LQQA 1NGEA 2JDQD 1ZFUA 2KJAA 5EXWA 5FPEA 5AQUA 4IO8A 1QQMA 3D2EB 1ZUTA 1NGBA 4KBOA 1B7DA 2MBKA 2KYQA 2KHOA 3LDPA 1SN1A 2YC1C 2YBRC 3PSMA 4GNIA 1WWNA 2N66A 3KC6A 3L56A 3FZHA 3FZFA 2QW9A 3M3ZA 1BK8A 2LY6A 1BUPA 1K8BA 2YIOA 3D2FA 1I2VA 2YIPA 3LDQA 2E88A 2LR3A 2YILA 3QI7A 5BPMA 3C7NA 3I33A 5AQKA 5F2RA 2MZ0A 1WT7A 2SN3A 1NGFA 3FZMA 5EVZA 5FPNA 2BRZA 1XRSB 1TI5A 4H5TA 4HHFA 1QQOA 1KAZA 5AR0A 1NE5A 1KV0A 2KPYA 2A7TA 1JKZA 1ZYWA 2N69A 5AQLA 1S3XA 1MYNA 2M8BB 1BCGA 3JXUA 3D2EA 3QFUA 5AQHA 5AQXA 1ATRA 4UADE 1NGHA 3LDLA 5BPLA 3AY9A 2NY8X 1C56A 1T7BA 2LN8A 4HWIA 1NGGA 3KP1A 1GPSA 4H5RA 1OMYA 2V7ZA 3ATUA 5AQJA 2BUPA 4UAFE 5AQTA 1NGDA 1LQHA 1P0AA 2LJ7A 5AQMA 3LDOA 2KBJA 2LT8A 2QWLA 4UJ0A 1NRBA 2KBHA 3KVGA 2KBKA 2KSKA 2G2KA 1CHZA 5AQOA 2YEOA 2GMOA 1NGIA 2E3GA 2NY9X 3IUCA 1L4VA 2LKBA 3KOWA 5AQFA 1LQIA 5AQRA 2VY6A 1BMRA 1ZYVA 1DQ7A 3FZLA 1SNBA 1ZVEA 4H5WA 1GPTA 5AQIA 1JZBA 1KAYA 5AQNA 2QWNA 2I61A 1PE4A 3L6QA 1YUWA 3CQXA 1B3CA 2D56A 1VNBA 1AYJA 4KYPA 3GL1A 5AQYA 2LI7A 1PX9A 5BPNA 5CY0A 1HPMA 5EX5A 1AHOA 1I6FA 1T1TA 1ZU3A 2QWMA 1NRAA 2KGQA 3A8YA 3D2FB 3KOZA 1FH3A 3L4IA 2LY5A 1I2UA 1BRZA 4FSVA 4AAZA 3C7NB 1ZVGA 2QWQA 3E7UX 4FL9A 1DKGD 3CW4A 1JZAA 4H5VA 3BK3C 3R2VA 5AQSA 1WMTA 2ATBA 1MR4A 5AQZA 3FZKA 3GDQA 1NGCA 1NGAA 1OZZA 1NGJA 4UAEF 2QWOA 1T0ZA 3KOYA 5BN8A 4AEIA 2B3CA 2LJMA 1NH5A 1BA1A 1JXCA 1T7EA 2B68A 3GKUA 5AQQA 1BA0A 5F1XA 2K35A 4CQKA 5AQGA 5FPMA 1HJOA 2MN5A
chains in the Genus database with same CATH topology
2ASCA 2E0HA 1I6GA 1SEGA 1C55A 5KK4A 1PTXA 2GL1A 3E7RL 4V1DC 1T7AA 2E3FA 4HE7A 1N4NA 1P00A 1DJTA 1SN4A 2N2RA 1VNAA 1NPIA 1ICAA 2N2QA 4AB0A 1LQQA 2KJAA 1ZFUA 1ZUTA 1B7DA 2KYQA 1SN1A 2YC1C 2YBRC 3PSMA 1WWNA 2N66A 1BK8A 2LY6A 1I2VA 2LR3A 2MZ0A 1WT7A 2SN3A 2BRZA 1TI5A 4HHFA 1NE5A 1KV0A 2KPYA 2A7TA 1JKZA 1ZYWA 2N69A 1MYNA 2M8BB 1BCGA 2NY8X 1C56A 1T7BA 1GPSA 1OMYA 1P0AA 1LQHA 2LJ7A 4UJ0A 1CN2A 2KBJA 2LT8A 1NRBA 2KBHA 2KBKA 2KSKA 1CHZA 2YEOA 2E3GA 2NY9X 1L4VA 2LKBA 1LQIA 1BMRA 1ZYVA 1DQ7A 1SNBA 1ZVEA 1GPTA 1JZBA 2I61A 1PE4A 1B3CA 1VNBA 1AYJA 4KYPA 5CY0A 2LI7A 1PX9A 1AHOA 1I6FA 1T1TA 1ZU3A 1NRAA 2KGQA 1FH3A 2LY5A 1I2UA 1BRZA 4AAZA 1ZVGA 3E7UX 1JZAA 1WMTA 2ATBA 1MR4A 1OZZA 1T0ZA 4AEIA 2B3CA 2LJMA 1NH5A 1JXCA 1T7EA 2B68A 4CQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ASC A;  2E0H A;  1I6G A;  1SEG A;  1C55 A;  5KK4 A;  1PTX A;  2GL1 A;  3E7R L;  4V1D C;  1T7A A;  2E3F A;  4HE7 A;  1N4N A;  1P00 A;  1DJT A;  1SN4 A;  2N2R A;  1VNA A;  1NPI A;  1ICA A;  2N2Q A;  4AB0 A;  1LQQ A;  2KJA A;  1ZFU A;  1ZUT A;  1B7D A;  2KYQ A;  1SN1 A;  2YC1 C;  2YBR C;  3PSM A;  1WWN A;  2N66 A;  1BK8 A;  2LY6 A;  1I2V A;  2LR3 A;  2MZ0 A;  1WT7 A;  2SN3 A;  2BRZ A;  1TI5 A;  4HHF A;  1NE5 A;  1KV0 A;  2KPY A;  2A7T A;  1JKZ A;  1ZYW A;  2N69 A;  1MYN A;  2M8B B;  1BCG A;  2NY8 X;  1C56 A;  1T7B A;  1GPS A;  1OMY A;  1P0A A;  1LQH A;  2LJ7 A;  4UJ0 A;  1CN2 A;  2KBJ A;  2LT8 A;  1NRB A;  2KBH A;  2KBK A;  2KSK A;  1CHZ A;  2YEO A;  2E3G A;  2NY9 X;  1L4V A;  2LKB A;  1LQI A;  1BMR A;  1ZYV A;  1DQ7 A;  1SNB A;  1ZVE A;  1GPT A;  1JZB A;  2I61 A;  1PE4 A;  1B3C A;  1VNB A;  1AYJ A;  4KYP A;  5CY0 A;  2LI7 A;  1PX9 A;  1AHO A;  1I6F A;  1T1T A;  1ZU3 A;  1NRA A;  2KGQ A;  1FH3 A;  2LY5 A;  1I2U A;  1BRZ A;  4AAZ A;  1ZVG A;  3E7U X;  1JZA A;  1WMT A;  2ATB A;  1MR4 A;  1OZZ A;  1T0Z A;  4AEI A;  2B3C A;  2LJM A;  1NH5 A;  1JXC A;  1T7E A;  2B68 A;  4CQK A; 
#chains in the Genus database with same CATH topology
 2ASC A;  2E0H A;  1I6G A;  5BN9 A;  2QWR A;  1SEG A;  1QQN A;  5KK4 A;  3KHW A;  1C55 A;  1ATS A;  1PTX A;  3HSC A;  2GL1 A;  3E7R L;  3FE1 A;  4V1D C;  5FPD A;  1T7A A;  5EY4 A;  2E3F A;  2E2F A;  4HE7 A;  5F0X A;  1N4N A;  1P00 A;  1DJT A;  1SN4 A;  2E8A A;  2N2R A;  3QML A;  3KP0 A;  1POI A;  3QFP A;  1VNA A;  5AQV A;  3KOX A;  2QXL A;  3SF4 D;  5AQP A;  1HX1 A;  2QWP A;  5AQW A;  3ATV A;  1NPI A;  4H5N A;  1KAX A;  1CN2 A;  3LDN A;  1ICA A;  1UGL A;  2N2Q A;  4AB0 A;  1LQQ A;  1NGE A;  2JDQ D;  1ZFU A;  2KJA A;  5EXW A;  5FPE A;  5AQU A;  4IO8 A;  1QQM A;  3D2E B;  1ZUT A;  1NGB A;  4KBO A;  1B7D A;  2MBK A;  2KYQ A;  2KHO A;  3LDP A;  1SN1 A;  2YC1 C;  2YBR C;  3PSM A;  4GNI A;  1WWN A;  2N66 A;  3KC6 A;  3L56 A;  3FZH A;  3FZF A;  2QW9 A;  3M3Z A;  1BK8 A;  2LY6 A;  1BUP A;  1K8B A;  2YIO A;  3D2F A;  1I2V A;  2YIP A;  3LDQ A;  2E88 A;  2LR3 A;  2YIL A;  3QI7 A;  5BPM A;  3C7N A;  3I33 A;  5AQK A;  5F2R A;  2MZ0 A;  1WT7 A;  2SN3 A;  1NGF A;  3FZM A;  5EVZ A;  5FPN A;  2BRZ A;  1XRS B;  1TI5 A;  4H5T A;  4HHF A;  1QQO A;  1KAZ A;  5AR0 A;  1NE5 A;  1KV0 A;  2KPY A;  2A7T A;  1JKZ A;  1ZYW A;  2N69 A;  5AQL A;  1S3X A;  1MYN A;  2M8B B;  1BCG A;  3JXU A;  3D2E A;  3QFU A;  5AQH A;  5AQX A;  1ATR A;  4UAD E;  1NGH A;  3LDL A;  5BPL A;  3AY9 A;  2NY8 X;  1C56 A;  1T7B A;  2LN8 A;  4HWI A;  1NGG A;  3KP1 A;  1GPS A;  4H5R A;  1OMY A;  2V7Z A;  3ATU A;  5AQJ A;  2BUP A;  4UAF E;  5AQT A;  1NGD A;  1LQH A;  1P0A A;  2LJ7 A;  5AQM A;  3LDO A;  2KBJ A;  2LT8 A;  2QWL A;  4UJ0 A;  1NRB A;  2KBH A;  3KVG A;  2KBK A;  2KSK A;  2G2K A;  1CHZ A;  5AQO A;  2YEO A;  2GMO A;  1NGI A;  2E3G A;  2NY9 X;  3IUC A;  1L4V A;  2LKB A;  3KOW A;  5AQF A;  1LQI A;  5AQR A;  2VY6 A;  1BMR A;  1ZYV A;  1DQ7 A;  3FZL A;  1SNB A;  1ZVE A;  4H5W A;  1GPT A;  5AQI A;  1JZB A;  1KAY A;  5AQN A;  2QWN A;  2I61 A;  1PE4 A;  3L6Q A;  1YUW A;  3CQX A;  1B3C A;  2D56 A;  1VNB A;  1AYJ A;  4KYP A;  3GL1 A;  5AQY A;  2LI7 A;  1PX9 A;  5BPN A;  5CY0 A;  1HPM A;  5EX5 A;  1AHO A;  1I6F A;  1T1T A;  1ZU3 A;  2QWM A;  1NRA A;  2KGQ A;  3A8Y A;  3D2F B;  3KOZ A;  1FH3 A;  3L4I A;  2LY5 A;  1I2U A;  1BRZ A;  4FSV A;  4AAZ A;  3C7N B;  1ZVG A;  2QWQ A;  3E7U X;  4FL9 A;  1DKG D;  3CW4 A;  1JZA A;  4H5V A;  3BK3 C;  3R2V A;  5AQS A;  1WMT A;  2ATB A;  1MR4 A;  5AQZ A;  3FZK A;  3GDQ A;  1NGC A;  1NGA A;  1OZZ A;  1NGJ A;  4UAE F;  2QWO A;  1T0Z A;  3KOY A;  5BN8 A;  4AEI A;  2B3C A;  2LJM A;  1NH5 A;  1BA1 A;  1JXC A;  1T7E A;  2B68 A;  3GKU A;  5AQQ A;  1BA0 A;  5F1X A;  2K35 A;  4CQK A;  5AQG A;  5FPM A;  1HJO A;  2MN5 A; 
#chains in the Genus database with same CATH homology
 2ASC A;  2E0H A;  1I6G A;  1SEG A;  1C55 A;  5KK4 A;  1PTX A;  2GL1 A;  3E7R L;  4V1D C;  1T7A A;  2E3F A;  4HE7 A;  1N4N A;  1P00 A;  1DJT A;  1SN4 A;  2N2R A;  1VNA A;  1NPI A;  1ICA A;  2N2Q A;  4AB0 A;  1LQQ A;  2KJA A;  1ZFU A;  1ZUT A;  1B7D A;  2KYQ A;  1SN1 A;  2YC1 C;  2YBR C;  3PSM A;  1WWN A;  2N66 A;  1BK8 A;  2LY6 A;  1I2V A;  2LR3 A;  2MZ0 A;  1WT7 A;  2SN3 A;  2BRZ A;  1TI5 A;  4HHF A;  1NE5 A;  1KV0 A;  2KPY A;  2A7T A;  1JKZ A;  1ZYW A;  2N69 A;  1MYN A;  2M8B B;  1BCG A;  2NY8 X;  1C56 A;  1T7B A;  1GPS A;  1OMY A;  1P0A A;  1LQH A;  2LJ7 A;  4UJ0 A;  1CN2 A;  2KBJ A;  2LT8 A;  1NRB A;  2KBH A;  2KBK A;  2KSK A;  1CHZ A;  2YEO A;  2E3G A;  2NY9 X;  1L4V A;  2LKB A;  1LQI A;  1BMR A;  1ZYV A;  1DQ7 A;  1SNB A;  1ZVE A;  1GPT A;  1JZB A;  2I61 A;  1PE4 A;  1B3C A;  1VNB A;  1AYJ A;  4KYP A;  5CY0 A;  2LI7 A;  1PX9 A;  1AHO A;  1I6F A;  1T1T A;  1ZU3 A;  1NRA A;  2KGQ A;  1FH3 A;  2LY5 A;  1I2U A;  1BRZ A;  4AAZ A;  1ZVG A;  3E7U X;  1JZA A;  1WMT A;  2ATB A;  1MR4 A;  1OZZ A;  1T0Z A;  4AEI A;  2B3C A;  2LJM A;  1NH5 A;  1JXC A;  1T7E A;  2B68 A;  4CQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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