2E3FA

Nmr structure of def-bat, a mutant of anopheles defensin def-aaa
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
43
structure length
43
Chain Sequence
ATCDLASFSSQWVTPNDSLCAAHCIARRYRGGYCNGKRVCVCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule keywords defensin, mutant DEF-BAT
molecule tags Antimicrobial protein
source organism Anopheles gambiae
total genus 7
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3fA00
2KBHA 4HHFA 2KYQA 2M8BB 2A7TA 1SNBA 1B7DA 2LKBA 1MR4A 1T7BA 1I2VA 1PE4A 4HE7A 2LR3A 1NPIA 1T7AA 1BRZA 1LQIA 2B68A 1JKZA 2NY8X 1ZFUA 2NY9X 1BMRA 2KSKA 1WWNA 1OZZA 2GL1A 2MZ0A 1I2UA 2E3FA 3E7UX 1DJTA 1NE5A 1DQ7A 1JZBA 2SN3A 1AYJA 2YBRC 1WT7A 4V1DC 2I61A 1JXCA 4KYPA 1ZVEA 4CQKA 2KBJA 2LT8A 2E0HA 1C56A 1LQHA 2B3CA 1ZU3A 2LI7A 1SN1A 1ZYWA 1NH5A 1CN2A 1PTXA 4UJ0A 2N2RA 4AEIA 2N66A 1FH3A 2YC1C 4AB0A 5KK4A 1C55A 2KJAA 1T1TA 2N2QA 1I6GA 1JZAA 2E3GA 1ICAA 5CY0A 3PSMA 2LJ7A 2BRZA 1NRBA 4AAZA 1NRAA 1ZUTA 1T0ZA 2KBKA 1WMTA 2YEOA 3E7RL 1GPTA 1VNBA 1T7EA 2ATBA 1BK8A 1AHOA 1MYNA 1BCGA 1SEGA 1LQQA 1KV0A 2LY6A 1ZVGA 1CHZA 2KPYA 1VNAA 2N69A 1P0AA 1PX9A 2LJMA 1B3CA 1GPSA 2KGQA 1P00A 1TI5A 2LY5A 2ASCA 1ZYVA 1L4VA 1I6FA 1N4NA 1OMYA 1SN4A
chains in the Genus database with same CATH superfamily
1KAZA 2YIPA 2E8AA 2KBHA 3KOWA 4HHFA 1BA0A 5AQMA 2KYQA 2YILA 2M8BB 2A7TA 5AQQA 1NGGA 1SNBA 1QQNA 1B7DA 3FZFA 1NGCA 2LKBA 1MR4A 2QWRA 5BPLA 1T7BA 5EY4A 1I2VA 1PE4A 4HE7A 2LR3A 1NPIA 3KOXA 3LDLA 5EX5A 5AQZA 1T7AA 3IUCA 5F0XA 3C7NA 1NGBA 1BRZA 3L6QA 4IO8A 1XRSB 3D2EB 1HX1A 2VY6A 1LQIA 4H5NA 2B68A 1UGLA 1JKZA 1NGIA 2NY8X 4HWIA 2QWQA 1ZFUA 2NY9X 5BPNA 1BMRA 4H5TA 2KSKA 5AQTA 1WWNA 1OZZA 2GL1A 5AQFA 2MZ0A 1QQMA 2BUPA 2QWOA 1I2UA 2E3FA 2QW9A 1YUWA 3D2EA 2QWLA 3E7UX 2JDQD 3KP0A 1DJTA 5AR0A 5AQOA 3M3ZA 1NE5A 3QFUA 3AY9A 1ATRA 3HSCA 2QXLA 1DQ7A 1JZBA 2SN3A 2MBKA 1AYJA 2YBRC 1WT7A 4V1DC 3GL1A 2I61A 3SF4D 1JXCA 2K35A 2LN8A 1ZVEA 4KYPA 2KBJA 2LT8A 4CQKA 1NGJA 2E0HA 3CQXA 1C56A 3L4IA 5EVZA 3L56A 1LQHA 2B3CA 1ZU3A 5AQXA 2LI7A 5FPMA 1SN1A 1K8BA 1NH5A 1ZYWA 4KBOA 1PTXA 5F2RA 4UJ0A 5BPMA 1CN2A 2N2RA 4UAEF 3I33A 1KAXA 3ATVA 3CW4A 4AEIA 1BUPA 2N66A 2QWMA 1FH3A 1BA1A 2YC1C 1NGFA 4AB0A 5F1XA 3KOYA 5KK4A 1C55A 4H5RA 2KJAA 1T1TA 3FZHA 3FZLA 3FE1A 3LDNA 2N2QA 4GNIA 2YIOA 1I6GA 5AQKA 3GDQA 1JZAA 3KHWA 2E3GA 1ICAA 5CY0A 3R2VA 3D2FB 3PSMA 1ATSA 2LJ7A 2G2KA 4H5VA 2BRZA 3A8YA 5AQHA 1NRBA 5AQIA 1NRAA 5AQLA 3JXUA 1ZUTA 5AQPA 5BN9A 4AAZA 1NGAA 1T0ZA 2KBKA 3ATUA 1WMTA 5AQVA 5FPDA 2E2FA 4FL9A 3LDOA 2GMOA 4UADE 3FZMA 2YEOA 1HPMA 3E7RL 1NGDA 2V7ZA 1GPTA 2MN5A 3QI7A 5EXWA 3KC6A 1NGHA 1VNBA 5AQWA 1T7EA 1S3XA 2ATBA 3KVGA 4UAFE 1BK8A 3QFPA 1AHOA 1HJOA 1MYNA 3BK3C 5AQSA 1BCGA 1SEGA 1LQQA 2QWPA 1KV0A 2QWNA 1QQOA 2LY6A 1ZVGA 3D2FA 1DKGD 1CHZA 2KPYA 3QMLA 2KHOA 3GKUA 1KAYA 1VNAA 2N69A 3FZKA 1P0AA 3KOZA 1PX9A 3LDQA 5AQYA 2LJMA 3KP1A 1B3CA 1GPSA 2KGQA 5AQJA 1P00A 1TI5A 5AQRA 2LY5A 2ASCA 1ZYVA 2D56A 4FSVA 1L4VA 1POIA 1I6FA 4H5WA 5BN8A 1N4NA 1NGEA 3C7NB 2E88A 1OMYA 5FPNA 5FPEA 5AQGA 1SN4A 3LDPA 5AQUA 5AQNA
chains in the Genus database with same CATH topology
2KBHA 4HHFA 2KYQA 2M8BB 2A7TA 1SNBA 1B7DA 2LKBA 1MR4A 1T7BA 1I2VA 1PE4A 4HE7A 2LR3A 1NPIA 1T7AA 1BRZA 1LQIA 2B68A 1JKZA 2NY8X 1ZFUA 2NY9X 1BMRA 2KSKA 1WWNA 1OZZA 2GL1A 2MZ0A 1I2UA 2E3FA 3E7UX 1DJTA 1NE5A 1DQ7A 1JZBA 2SN3A 1AYJA 2YBRC 1WT7A 4V1DC 2I61A 1JXCA 4KYPA 1ZVEA 4CQKA 2KBJA 2LT8A 2E0HA 1C56A 1LQHA 2B3CA 1ZU3A 2LI7A 1SN1A 1ZYWA 1NH5A 1CN2A 1PTXA 4UJ0A 2N2RA 4AEIA 2N66A 1FH3A 2YC1C 4AB0A 5KK4A 1C55A 2KJAA 1T1TA 2N2QA 1I6GA 1JZAA 2E3GA 1ICAA 5CY0A 3PSMA 2LJ7A 2BRZA 1NRBA 4AAZA 1NRAA 1ZUTA 1T0ZA 2KBKA 1WMTA 2YEOA 3E7RL 1GPTA 1VNBA 1T7EA 2ATBA 1BK8A 1AHOA 1MYNA 1BCGA 1SEGA 1LQQA 1KV0A 2LY6A 1ZVGA 1CHZA 2KPYA 1VNAA 2N69A 1P0AA 1PX9A 2LJMA 1B3CA 1GPSA 2KGQA 1P00A 1TI5A 2LY5A 2ASCA 1ZYVA 1L4VA 1I6FA 1N4NA 1OMYA 1SN4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBH A;  4HHF A;  2KYQ A;  2M8B B;  2A7T A;  1SNB A;  1B7D A;  2LKB A;  1MR4 A;  1T7B A;  1I2V A;  1PE4 A;  4HE7 A;  2LR3 A;  1NPI A;  1T7A A;  1BRZ A;  1LQI A;  2B68 A;  1JKZ A;  2NY8 X;  1ZFU A;  2NY9 X;  1BMR A;  2KSK A;  1WWN A;  1OZZ A;  2GL1 A;  2MZ0 A;  1I2U A;  2E3F A;  3E7U X;  1DJT A;  1NE5 A;  1DQ7 A;  1JZB A;  2SN3 A;  1AYJ A;  2YBR C;  1WT7 A;  4V1D C;  2I61 A;  1JXC A;  4KYP A;  1ZVE A;  4CQK A;  2KBJ A;  2LT8 A;  2E0H A;  1C56 A;  1LQH A;  2B3C A;  1ZU3 A;  2LI7 A;  1SN1 A;  1ZYW A;  1NH5 A;  1CN2 A;  1PTX A;  4UJ0 A;  2N2R A;  4AEI A;  2N66 A;  1FH3 A;  2YC1 C;  4AB0 A;  5KK4 A;  1C55 A;  2KJA A;  1T1T A;  2N2Q A;  1I6G A;  1JZA A;  2E3G A;  1ICA A;  5CY0 A;  3PSM A;  2LJ7 A;  2BRZ A;  1NRB A;  4AAZ A;  1NRA A;  1ZUT A;  1T0Z A;  2KBK A;  1WMT A;  2YEO A;  3E7R L;  1GPT A;  1VNB A;  1T7E A;  2ATB A;  1BK8 A;  1AHO A;  1MYN A;  1BCG A;  1SEG A;  1LQQ A;  1KV0 A;  2LY6 A;  1ZVG A;  1CHZ A;  2KPY A;  1VNA A;  2N69 A;  1P0A A;  1PX9 A;  2LJM A;  1B3C A;  1GPS A;  2KGQ A;  1P00 A;  1TI5 A;  2LY5 A;  2ASC A;  1ZYV A;  1L4V A;  1I6F A;  1N4N A;  1OMY A;  1SN4 A; 
#chains in the Genus database with same CATH topology
 1KAZ A;  2YIP A;  2E8A A;  2KBH A;  3KOW A;  4HHF A;  1BA0 A;  5AQM A;  2KYQ A;  2YIL A;  2M8B B;  2A7T A;  5AQQ A;  1NGG A;  1SNB A;  1QQN A;  1B7D A;  3FZF A;  1NGC A;  2LKB A;  1MR4 A;  2QWR A;  5BPL A;  1T7B A;  5EY4 A;  1I2V A;  1PE4 A;  4HE7 A;  2LR3 A;  1NPI A;  3KOX A;  3LDL A;  5EX5 A;  5AQZ A;  1T7A A;  3IUC A;  5F0X A;  3C7N A;  1NGB A;  1BRZ A;  3L6Q A;  4IO8 A;  1XRS B;  3D2E B;  1HX1 A;  2VY6 A;  1LQI A;  4H5N A;  2B68 A;  1UGL A;  1JKZ A;  1NGI A;  2NY8 X;  4HWI A;  2QWQ A;  1ZFU A;  2NY9 X;  5BPN A;  1BMR A;  4H5T A;  2KSK A;  5AQT A;  1WWN A;  1OZZ A;  2GL1 A;  5AQF A;  2MZ0 A;  1QQM A;  2BUP A;  2QWO A;  1I2U A;  2E3F A;  2QW9 A;  1YUW A;  3D2E A;  2QWL A;  3E7U X;  2JDQ D;  3KP0 A;  1DJT A;  5AR0 A;  5AQO A;  3M3Z A;  1NE5 A;  3QFU A;  3AY9 A;  1ATR A;  3HSC A;  2QXL A;  1DQ7 A;  1JZB A;  2SN3 A;  2MBK A;  1AYJ A;  2YBR C;  1WT7 A;  4V1D C;  3GL1 A;  2I61 A;  3SF4 D;  1JXC A;  2K35 A;  2LN8 A;  1ZVE A;  4KYP A;  2KBJ A;  2LT8 A;  4CQK A;  1NGJ A;  2E0H A;  3CQX A;  1C56 A;  3L4I A;  5EVZ A;  3L56 A;  1LQH A;  2B3C A;  1ZU3 A;  5AQX A;  2LI7 A;  5FPM A;  1SN1 A;  1K8B A;  1NH5 A;  1ZYW A;  4KBO A;  1PTX A;  5F2R A;  4UJ0 A;  5BPM A;  1CN2 A;  2N2R A;  4UAE F;  3I33 A;  1KAX A;  3ATV A;  3CW4 A;  4AEI A;  1BUP A;  2N66 A;  2QWM A;  1FH3 A;  1BA1 A;  2YC1 C;  1NGF A;  4AB0 A;  5F1X A;  3KOY A;  5KK4 A;  1C55 A;  4H5R A;  2KJA A;  1T1T A;  3FZH A;  3FZL A;  3FE1 A;  3LDN A;  2N2Q A;  4GNI A;  2YIO A;  1I6G A;  5AQK A;  3GDQ A;  1JZA A;  3KHW A;  2E3G A;  1ICA A;  5CY0 A;  3R2V A;  3D2F B;  3PSM A;  1ATS A;  2LJ7 A;  2G2K A;  4H5V A;  2BRZ A;  3A8Y A;  5AQH A;  1NRB A;  5AQI A;  1NRA A;  5AQL A;  3JXU A;  1ZUT A;  5AQP A;  5BN9 A;  4AAZ A;  1NGA A;  1T0Z A;  2KBK A;  3ATU A;  1WMT A;  5AQV A;  5FPD A;  2E2F A;  4FL9 A;  3LDO A;  2GMO A;  4UAD E;  3FZM A;  2YEO A;  1HPM A;  3E7R L;  1NGD A;  2V7Z A;  1GPT A;  2MN5 A;  3QI7 A;  5EXW A;  3KC6 A;  1NGH A;  1VNB A;  5AQW A;  1T7E A;  1S3X A;  2ATB A;  3KVG A;  4UAF E;  1BK8 A;  3QFP A;  1AHO A;  1HJO A;  1MYN A;  3BK3 C;  5AQS A;  1BCG A;  1SEG A;  1LQQ A;  2QWP A;  1KV0 A;  2QWN A;  1QQO A;  2LY6 A;  1ZVG A;  3D2F A;  1DKG D;  1CHZ A;  2KPY A;  3QML A;  2KHO A;  3GKU A;  1KAY A;  1VNA A;  2N69 A;  3FZK A;  1P0A A;  3KOZ A;  1PX9 A;  3LDQ A;  5AQY A;  2LJM A;  3KP1 A;  1B3C A;  1GPS A;  2KGQ A;  5AQJ A;  1P00 A;  1TI5 A;  5AQR A;  2LY5 A;  2ASC A;  1ZYV A;  2D56 A;  4FSV A;  1L4V A;  1POI A;  1I6F A;  4H5W A;  5BN8 A;  1N4N A;  1NGE A;  3C7N B;  2E88 A;  1OMY A;  5FPN A;  5FPE A;  5AQG A;  1SN4 A;  3LDP A;  5AQU A;  5AQN A; 
#chains in the Genus database with same CATH homology
 2KBH A;  4HHF A;  2KYQ A;  2M8B B;  2A7T A;  1SNB A;  1B7D A;  2LKB A;  1MR4 A;  1T7B A;  1I2V A;  1PE4 A;  4HE7 A;  2LR3 A;  1NPI A;  1T7A A;  1BRZ A;  1LQI A;  2B68 A;  1JKZ A;  2NY8 X;  1ZFU A;  2NY9 X;  1BMR A;  2KSK A;  1WWN A;  1OZZ A;  2GL1 A;  2MZ0 A;  1I2U A;  2E3F A;  3E7U X;  1DJT A;  1NE5 A;  1DQ7 A;  1JZB A;  2SN3 A;  1AYJ A;  2YBR C;  1WT7 A;  4V1D C;  2I61 A;  1JXC A;  4KYP A;  1ZVE A;  4CQK A;  2KBJ A;  2LT8 A;  2E0H A;  1C56 A;  1LQH A;  2B3C A;  1ZU3 A;  2LI7 A;  1SN1 A;  1ZYW A;  1NH5 A;  1CN2 A;  1PTX A;  4UJ0 A;  2N2R A;  4AEI A;  2N66 A;  1FH3 A;  2YC1 C;  4AB0 A;  5KK4 A;  1C55 A;  2KJA A;  1T1T A;  2N2Q A;  1I6G A;  1JZA A;  2E3G A;  1ICA A;  5CY0 A;  3PSM A;  2LJ7 A;  2BRZ A;  1NRB A;  4AAZ A;  1NRA A;  1ZUT A;  1T0Z A;  2KBK A;  1WMT A;  2YEO A;  3E7R L;  1GPT A;  1VNB A;  1T7E A;  2ATB A;  1BK8 A;  1AHO A;  1MYN A;  1BCG A;  1SEG A;  1LQQ A;  1KV0 A;  2LY6 A;  1ZVG A;  1CHZ A;  2KPY A;  1VNA A;  2N69 A;  1P0A A;  1PX9 A;  2LJM A;  1B3C A;  1GPS A;  2KGQ A;  1P00 A;  1TI5 A;  2LY5 A;  2ASC A;  1ZYV A;  1L4V A;  1I6F A;  1N4N A;  1OMY A;  1SN4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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