1ZYVA

Crystal structure of mutant k8dp9sr58kv59g of scorpion alpha-like neurotoxin bmk m1 from buthus martensii karsch
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
66
structure length
66
Chain Sequence
NSVRDAYIADSHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIKGPGKCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1
pubmed doi rcsb
molecule keywords Alpha-like neurotoxin BmK-I
molecule tags Toxin
source organism Mesobuthus martensii
total genus 18
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2005-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1zyvA00
2KBHA 1GPSA 1CN2A 1ZFUA 1VNAA 1C55A 1WWNA 2NY9X 1I6GA 1I2UA 3E7UX 2KPYA 4CQKA 1BCGA 1OZZA 1SEGA 2NY8X 2LY6A 2M8BB 1PE4A 2YBRC 1SNBA 2KSKA 2KYQA 2MZ0A 4AB0A 1I2VA 4AAZA 4UJ0A 1ZVEA 1MR4A 1VNBA 1LQQA 1JZAA 2N2RA 2KJAA 2YEOA 5KK4A 1BMRA 2E3FA 1L4VA 1B7DA 1N4NA 1T7AA 2LKBA 2N2QA 1ZYVA 1T0ZA 2E3GA 2YC1C 1ZVGA 2GL1A 1WMTA 1NRAA 1ICAA 2E0HA 1KV0A 2LY5A 4HE7A 1NRBA 3PSMA 1BK8A 1ZUTA 1WT7A 4AEIA 1P0AA 2B3CA 1ZYWA 1MYNA 1CHZA 2ATBA 4KYPA 1T7EA 1DQ7A 1OMYA 2I61A 1JKZA 1SN4A 2KBKA 1TI5A 1T1TA 1I6FA 1FH3A 1NE5A 2SN3A 1LQIA 4V1DC 2LR3A 2KBJA 5CY0A 1NPIA 1DJTA 1SN1A 2LJMA 2LI7A 1T7BA 1B3CA 1PTXA 1JXCA 1P00A 2N66A 4HHFA 1BRZA 2LJ7A 2KGQA 2B68A 1C56A 1AHOA 2N69A 1AYJA 3E7RL 2BRZA 2A7TA 1LQHA 1NH5A 2ASCA 1JZBA 1PX9A 1GPTA 1ZU3A 2LT8A
chains in the Genus database with same CATH superfamily
3L4IA 2KBHA 1NGIA 1GPSA 1HX1A 1CN2A 1QQMA 1ZFUA 1VNAA 1C55A 1WWNA 2G2KA 2NY9X 2LN8A 3D2EA 3FZLA 1I6GA 3E7UX 2KPYA 4CQKA 1BCGA 1I2UA 1OZZA 1SEGA 3L6QA 2NY8X 1S3XA 2LY6A 1PE4A 2M8BB 1SNBA 2KSKA 2KYQA 2MZ0A 2VY6A 2YBRC 3KOZA 2MN5A 3FZHA 4H5WA 4AAZA 4UJ0A 1ZVEA 3C7NA 1QQOA 1MR4A 1VNBA 2E88A 4HWIA 1LQQA 5AQYA 5F1XA 1JZAA 2N2RA 2QWOA 1ATRA 2KJAA 2YEOA 3CQXA 5AQRA 1BA0A 1K8BA 3QFUA 1UGLA 5KK4A 2YIPA 5AQZA 1BMRA 3LDQA 2E3FA 3LDPA 3FZMA 1QQNA 1L4VA 1NGAA 2GMOA 3FZFA 2D56A 1KAXA 1KAYA 5FPMA 5AQNA 1B7DA 3C7NB 3GDQA 3GL1A 1N4NA 1POIA 3D2FA 4AB0A 1T7AA 3KOYA 2LKBA 5AQLA 5AQPA 2N2QA 3M3ZA 1ZYVA 3IUCA 1T0ZA 2KHOA 4H5TA 5FPNA 2E3GA 2YC1C 1ZVGA 5BPMA 2GL1A 1WMTA 1NGEA 1NRAA 5AQGA 1ICAA 5F0XA 5AQVA 2E0HA 1KV0A 2LY5A 4H5VA 4HE7A 1HJOA 1NRBA 1YUWA 3BK3C 3PSMA 1ZUTA 3CW4A 3LDOA 3QMLA 5AQHA 5AQFA 1NGCA 1WT7A 3QFPA 3LDNA 2QWLA 5AQUA 4AEIA 3GKUA 1P0AA 3D2EB 2B3CA 5FPEA 1NGHA 3QI7A 1ZYWA 1MYNA 1CHZA 1NGJA 2ATBA 3FE1A 1HPMA 4KYPA 3SF4D 1T7EA 3KOWA 5AQWA 2QW9A 1DQ7A 5EY4A 1I2VA 1OMYA 3KC6A 2I61A 1JKZA 3R2VA 1SN4A 2KBKA 1TI5A 1T1TA 1I6FA 3KHWA 1FH3A 1NE5A 2V7ZA 3HSCA 4IO8A 3AY9A 1BK8A 5BPLA 2SN3A 2E8AA 1LQIA 4V1DC 3KP1A 2LR3A 3ATUA 3I33A 2KBJA 3ATVA 5AQMA 5CY0A 2E2FA 1XRSB 2YIOA 1NPIA 2QWNA 1DJTA 1SN1A 4UAFE 5BN9A 2QWQA 2LJMA 5AQXA 2MBKA 2LI7A 1T7BA 2QWMA 1BA1A 5AQJA 1B3CA 3KOXA 5BN8A 1NGFA 1DKGD 4H5RA 1PTXA 3D2FB 1JXCA 4FSVA 4UAEF 1P00A 5AQTA 2N66A 4HHFA 4GNIA 1NGGA 1BRZA 2LJ7A 5AQOA 2KGQA 2JDQD 4KBOA 3FZKA 5AQQA 2B68A 2QXLA 4H5NA 1C56A 1AHOA 1NGDA 2N69A 3L56A 4UADE 3KVGA 5EVZA 2QWRA 5EXWA 1AYJA 1KAZA 3LDLA 5F2RA 2YILA 5AQKA 1BUPA 3E7RL 5AQIA 5AQSA 1NGBA 2BRZA 5BPNA 5AR0A 2A7TA 1ATSA 2K35A 4FL9A 1LQHA 1NH5A 2QWPA 2ASCA 1JZBA 3KP0A 1PX9A 3JXUA 2BUPA 5FPDA 3A8YA 1GPTA 1ZU3A 2LT8A 5EX5A
chains in the Genus database with same CATH topology
2KBHA 1GPSA 1CN2A 1ZFUA 1VNAA 1C55A 1WWNA 2NY9X 1I6GA 1I2UA 3E7UX 2KPYA 4CQKA 1BCGA 1OZZA 1SEGA 2NY8X 2LY6A 2M8BB 1PE4A 2YBRC 1SNBA 2KSKA 2KYQA 2MZ0A 4AB0A 1I2VA 4AAZA 4UJ0A 1ZVEA 1MR4A 1VNBA 1LQQA 1JZAA 2N2RA 2KJAA 2YEOA 5KK4A 1BMRA 2E3FA 1L4VA 1B7DA 1N4NA 1T7AA 2LKBA 2N2QA 1ZYVA 1T0ZA 2E3GA 2YC1C 1ZVGA 2GL1A 1WMTA 1NRAA 1ICAA 2E0HA 1KV0A 2LY5A 4HE7A 1NRBA 3PSMA 1BK8A 1ZUTA 1WT7A 4AEIA 1P0AA 2B3CA 1ZYWA 1MYNA 1CHZA 2ATBA 4KYPA 1T7EA 1DQ7A 1OMYA 2I61A 1JKZA 1SN4A 2KBKA 1TI5A 1T1TA 1I6FA 1FH3A 1NE5A 2SN3A 1LQIA 4V1DC 2LR3A 2KBJA 5CY0A 1NPIA 1DJTA 1SN1A 2LJMA 2LI7A 1T7BA 1B3CA 1PTXA 1JXCA 1P00A 2N66A 4HHFA 1BRZA 2LJ7A 2KGQA 2B68A 1C56A 1AHOA 2N69A 1AYJA 3E7RL 2BRZA 2A7TA 1LQHA 1NH5A 2ASCA 1JZBA 1PX9A 1GPTA 1ZU3A 2LT8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBH A;  1GPS A;  1CN2 A;  1ZFU A;  1VNA A;  1C55 A;  1WWN A;  2NY9 X;  1I6G A;  1I2U A;  3E7U X;  2KPY A;  4CQK A;  1BCG A;  1OZZ A;  1SEG A;  2NY8 X;  2LY6 A;  2M8B B;  1PE4 A;  2YBR C;  1SNB A;  2KSK A;  2KYQ A;  2MZ0 A;  4AB0 A;  1I2V A;  4AAZ A;  4UJ0 A;  1ZVE A;  1MR4 A;  1VNB A;  1LQQ A;  1JZA A;  2N2R A;  2KJA A;  2YEO A;  5KK4 A;  1BMR A;  2E3F A;  1L4V A;  1B7D A;  1N4N A;  1T7A A;  2LKB A;  2N2Q A;  1ZYV A;  1T0Z A;  2E3G A;  2YC1 C;  1ZVG A;  2GL1 A;  1WMT A;  1NRA A;  1ICA A;  2E0H A;  1KV0 A;  2LY5 A;  4HE7 A;  1NRB A;  3PSM A;  1BK8 A;  1ZUT A;  1WT7 A;  4AEI A;  1P0A A;  2B3C A;  1ZYW A;  1MYN A;  1CHZ A;  2ATB A;  4KYP A;  1T7E A;  1DQ7 A;  1OMY A;  2I61 A;  1JKZ A;  1SN4 A;  2KBK A;  1TI5 A;  1T1T A;  1I6F A;  1FH3 A;  1NE5 A;  2SN3 A;  1LQI A;  4V1D C;  2LR3 A;  2KBJ A;  5CY0 A;  1NPI A;  1DJT A;  1SN1 A;  2LJM A;  2LI7 A;  1T7B A;  1B3C A;  1PTX A;  1JXC A;  1P00 A;  2N66 A;  4HHF A;  1BRZ A;  2LJ7 A;  2KGQ A;  2B68 A;  1C56 A;  1AHO A;  2N69 A;  1AYJ A;  3E7R L;  2BRZ A;  2A7T A;  1LQH A;  1NH5 A;  2ASC A;  1JZB A;  1PX9 A;  1GPT A;  1ZU3 A;  2LT8 A; 
#chains in the Genus database with same CATH topology
 3L4I A;  2KBH A;  1NGI A;  1GPS A;  1HX1 A;  1CN2 A;  1QQM A;  1ZFU A;  1VNA A;  1C55 A;  1WWN A;  2G2K A;  2NY9 X;  2LN8 A;  3D2E A;  3FZL A;  1I6G A;  3E7U X;  2KPY A;  4CQK A;  1BCG A;  1I2U A;  1OZZ A;  1SEG A;  3L6Q A;  2NY8 X;  1S3X A;  2LY6 A;  1PE4 A;  2M8B B;  1SNB A;  2KSK A;  2KYQ A;  2MZ0 A;  2VY6 A;  2YBR C;  3KOZ A;  2MN5 A;  3FZH A;  4H5W A;  4AAZ A;  4UJ0 A;  1ZVE A;  3C7N A;  1QQO A;  1MR4 A;  1VNB A;  2E88 A;  4HWI A;  1LQQ A;  5AQY A;  5F1X A;  1JZA A;  2N2R A;  2QWO A;  1ATR A;  2KJA A;  2YEO A;  3CQX A;  5AQR A;  1BA0 A;  1K8B A;  3QFU A;  1UGL A;  5KK4 A;  2YIP A;  5AQZ A;  1BMR A;  3LDQ A;  2E3F A;  3LDP A;  3FZM A;  1QQN A;  1L4V A;  1NGA A;  2GMO A;  3FZF A;  2D56 A;  1KAX A;  1KAY A;  5FPM A;  5AQN A;  1B7D A;  3C7N B;  3GDQ A;  3GL1 A;  1N4N A;  1POI A;  3D2F A;  4AB0 A;  1T7A A;  3KOY A;  2LKB A;  5AQL A;  5AQP A;  2N2Q A;  3M3Z A;  1ZYV A;  3IUC A;  1T0Z A;  2KHO A;  4H5T A;  5FPN A;  2E3G A;  2YC1 C;  1ZVG A;  5BPM A;  2GL1 A;  1WMT A;  1NGE A;  1NRA A;  5AQG A;  1ICA A;  5F0X A;  5AQV A;  2E0H A;  1KV0 A;  2LY5 A;  4H5V A;  4HE7 A;  1HJO A;  1NRB A;  1YUW A;  3BK3 C;  3PSM A;  1ZUT A;  3CW4 A;  3LDO A;  3QML A;  5AQH A;  5AQF A;  1NGC A;  1WT7 A;  3QFP A;  3LDN A;  2QWL A;  5AQU A;  4AEI A;  3GKU A;  1P0A A;  3D2E B;  2B3C A;  5FPE A;  1NGH A;  3QI7 A;  1ZYW A;  1MYN A;  1CHZ A;  1NGJ A;  2ATB A;  3FE1 A;  1HPM A;  4KYP A;  3SF4 D;  1T7E A;  3KOW A;  5AQW A;  2QW9 A;  1DQ7 A;  5EY4 A;  1I2V A;  1OMY A;  3KC6 A;  2I61 A;  1JKZ A;  3R2V A;  1SN4 A;  2KBK A;  1TI5 A;  1T1T A;  1I6F A;  3KHW A;  1FH3 A;  1NE5 A;  2V7Z A;  3HSC A;  4IO8 A;  3AY9 A;  1BK8 A;  5BPL A;  2SN3 A;  2E8A A;  1LQI A;  4V1D C;  3KP1 A;  2LR3 A;  3ATU A;  3I33 A;  2KBJ A;  3ATV A;  5AQM A;  5CY0 A;  2E2F A;  1XRS B;  2YIO A;  1NPI A;  2QWN A;  1DJT A;  1SN1 A;  4UAF E;  5BN9 A;  2QWQ A;  2LJM A;  5AQX A;  2MBK A;  2LI7 A;  1T7B A;  2QWM A;  1BA1 A;  5AQJ A;  1B3C A;  3KOX A;  5BN8 A;  1NGF A;  1DKG D;  4H5R A;  1PTX A;  3D2F B;  1JXC A;  4FSV A;  4UAE F;  1P00 A;  5AQT A;  2N66 A;  4HHF A;  4GNI A;  1NGG A;  1BRZ A;  2LJ7 A;  5AQO A;  2KGQ A;  2JDQ D;  4KBO A;  3FZK A;  5AQQ A;  2B68 A;  2QXL A;  4H5N A;  1C56 A;  1AHO A;  1NGD A;  2N69 A;  3L56 A;  4UAD E;  3KVG A;  5EVZ A;  2QWR A;  5EXW A;  1AYJ A;  1KAZ A;  3LDL A;  5F2R A;  2YIL A;  5AQK A;  1BUP A;  3E7R L;  5AQI A;  5AQS A;  1NGB A;  2BRZ A;  5BPN A;  5AR0 A;  2A7T A;  1ATS A;  2K35 A;  4FL9 A;  1LQH A;  1NH5 A;  2QWP A;  2ASC A;  1JZB A;  3KP0 A;  1PX9 A;  3JXU A;  2BUP A;  5FPD A;  3A8Y A;  1GPT A;  1ZU3 A;  2LT8 A;  5EX5 A; 
#chains in the Genus database with same CATH homology
 2KBH A;  1GPS A;  1CN2 A;  1ZFU A;  1VNA A;  1C55 A;  1WWN A;  2NY9 X;  1I6G A;  1I2U A;  3E7U X;  2KPY A;  4CQK A;  1BCG A;  1OZZ A;  1SEG A;  2NY8 X;  2LY6 A;  2M8B B;  1PE4 A;  2YBR C;  1SNB A;  2KSK A;  2KYQ A;  2MZ0 A;  4AB0 A;  1I2V A;  4AAZ A;  4UJ0 A;  1ZVE A;  1MR4 A;  1VNB A;  1LQQ A;  1JZA A;  2N2R A;  2KJA A;  2YEO A;  5KK4 A;  1BMR A;  2E3F A;  1L4V A;  1B7D A;  1N4N A;  1T7A A;  2LKB A;  2N2Q A;  1ZYV A;  1T0Z A;  2E3G A;  2YC1 C;  1ZVG A;  2GL1 A;  1WMT A;  1NRA A;  1ICA A;  2E0H A;  1KV0 A;  2LY5 A;  4HE7 A;  1NRB A;  3PSM A;  1BK8 A;  1ZUT A;  1WT7 A;  4AEI A;  1P0A A;  2B3C A;  1ZYW A;  1MYN A;  1CHZ A;  2ATB A;  4KYP A;  1T7E A;  1DQ7 A;  1OMY A;  2I61 A;  1JKZ A;  1SN4 A;  2KBK A;  1TI5 A;  1T1T A;  1I6F A;  1FH3 A;  1NE5 A;  2SN3 A;  1LQI A;  4V1D C;  2LR3 A;  2KBJ A;  5CY0 A;  1NPI A;  1DJT A;  1SN1 A;  2LJM A;  2LI7 A;  1T7B A;  1B3C A;  1PTX A;  1JXC A;  1P00 A;  2N66 A;  4HHF A;  1BRZ A;  2LJ7 A;  2KGQ A;  2B68 A;  1C56 A;  1AHO A;  2N69 A;  1AYJ A;  3E7R L;  2BRZ A;  2A7T A;  1LQH A;  1NH5 A;  2ASC A;  1JZB A;  1PX9 A;  1GPT A;  1ZU3 A;  2LT8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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