2E3GA

Nmr structure of def-daa, a mutant of anopheles defensin def-aaa
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
40
structure length
40
Chain Sequence
ATCDLASKWNWNHTLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Anopheles gambiae
molecule keywords defensin, mutant DEF-DAA
total genus 4
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3gA00
2N66A 2B68A 1FH3A 1I6FA 2KYQA 1OMYA 1ZFUA 1ZU3A 1TI5A 2LY5A 1LQHA 1DQ7A 1ZVGA 1ZYWA 2N2QA 1DJTA 2GL1A 1AHOA 1NRAA 4HE7A 1ZVEA 2KGQA 2E0HA 4AAZA 1PTXA 1WT7A 1ZYVA 2LT8A 4AB0A 4V1DC 1I2VA 1KV0A 5KK4A 3E7UX 2KJAA 1MYNA 1L4VA 2BRZA 3E7RL 1LQQA 4UJ0A 2NY8X 3PSMA 1NE5A 2LJMA 2MZ0A 1WWNA 2LJ7A 1BRZA 1T1TA 2E3GA 1C56A 2SN3A 2ASCA 2KBJA 4AEIA 2I61A 1ZUTA 1T0ZA 1JXCA 1JKZA 2NY9X 2YC1C 1PE4A 2KBHA 4KYPA 2M8BB 1AYJA 2B3CA 1SN1A 1T7AA 1T7BA 1BMRA 1VNBA 1I2UA 1BCGA 1GPTA 2LY6A 2YBRC 1P00A 1B3CA 1SEGA 2YEOA 1I6GA 2KBKA 2A7TA 1T7EA 5CY0A 2N2RA 1NRBA 1C55A 1B7DA 1N4NA 1VNAA 2E3FA 1BK8A 1GPSA 1CHZA 1ICAA 2KSKA 1PX9A 2LKBA 1SN4A 1WMTA 1SNBA 2LI7A 1LQIA 1P0AA 1NH5A 2KPYA 1NPIA 2N69A 4HHFA 1JZAA 2LR3A 2ATBA 4CQKA 1JZBA 1CN2A 1MR4A 1OZZA
chains in the Genus database with same CATH superfamily
2N66A 1YUWA 2B68A 4UAFE 3SF4D 1FH3A 3KP1A 1I6FA 5AQPA 2KYQA 1OMYA 2KHOA 2D56A 2QWNA 2QWRA 2QWQA 1ZFUA 2YIPA 5AQHA 1ZU3A 3C7NA 5EY4A 1TI5A 2LY5A 1NGGA 1LQHA 1DQ7A 1ZVGA 1NGFA 1NGJA 2YILA 1ZYWA 1NGIA 4UADE 2N2QA 1DJTA 2GL1A 5BPNA 2QXLA 3GKUA 3KVGA 4FL9A 2K35A 1AHOA 1NRAA 4HE7A 1ZVEA 3AY9A 2KGQA 2QWOA 3KC6A 5AQJA 1NGAA 2E0HA 1NGCA 1S3XA 3FZMA 4AAZA 1PTXA 4H5RA 3D2FA 3KHWA 1I2VA 1WT7A 1KAXA 5AQYA 1ZYVA 3A8YA 2LT8A 1XRSB 4V1DC 1UGLA 1KV0A 3QMLA 4AB0A 5KK4A 3E7UX 3M3ZA 5BN9A 2KJAA 3QI7A 1MYNA 2QWMA 1L4VA 2JDQD 3LDQA 2BRZA 4FSVA 3E7RL 1LQQA 3HSCA 3LDOA 5AQGA 4UJ0A 5AQQA 2NY8X 3L6QA 3PSMA 3GL1A 1NE5A 3JXUA 2E88A 2LJMA 1WWNA 2MZ0A 3LDNA 2LJ7A 5AQVA 3D2EA 2MBKA 1BA0A 1NGHA 3C7NB 5AQKA 5AQNA 5EVZA 2LN8A 1T1TA 5AQWA 5F2RA 2E3GA 1C56A 2SN3A 1DKGD 2ASCA 3CQXA 2KBJA 3QFPA 5AQRA 4HWIA 3FZFA 2QW9A 5AQMA 5AQTA 2I61A 2QWPA 1ZUTA 3KOYA 4GNIA 4AEIA 1T0ZA 1JXCA 3ATUA 1JKZA 2NY9X 2YC1C 1PE4A 2KBHA 2YIOA 1BUPA 4KYPA 2QWLA 5AQFA 5FPNA 2M8BB 1AYJA 5AQLA 5FPDA 2B3CA 1SN1A 2GMOA 1T7AA 1T7BA 3CW4A 3R2VA 1BMRA 3D2FB 5AQXA 1VNBA 1I2UA 1BCGA 1BRZA 3FE1A 1GPTA 2LY6A 2YBRC 5EX5A 4H5NA 4UAEF 1P00A 1ATSA 5F1XA 1HJOA 5AQIA 1B3CA 1SEGA 2YEOA 4IO8A 2KBKA 1I6GA 3L56A 2A7TA 1ATRA 1T7EA 5CY0A 2G2KA 3IUCA 5AQOA 2N2RA 3KOWA 1NRBA 4KBOA 1CN2A 5AR0A 2VY6A 1C55A 1NGEA 1NGDA 1B7DA 1N4NA 1VNAA 3ATVA 1K8BA 3D2EB 1POIA 1NGBA 2E3FA 5AQSA 5EXWA 1BK8A 1GPSA 1CHZA 1ICAA 2MN5A 3KOZA 5AQUA 1PX9A 2KSKA 2LKBA 1KAYA 1QQMA 1SN4A 5F0XA 2BUPA 5BN8A 3FZKA 1WMTA 1SNBA 2LI7A 1LQIA 3GDQA 1P0AA 3KOXA 5FPMA 3L4IA 1QQOA 5FPEA 2V7ZA 1NH5A 1KAZA 3LDLA 4H5TA 4H5VA 2KPYA 2E8AA 3BK3C 3FZHA 5BPMA 1BA1A 2E2FA 3LDPA 1NPIA 1HX1A 2N69A 4HHFA 1JZAA 4H5WA 3I33A 2LR3A 3FZLA 1HPMA 2ATBA 1QQNA 5BPLA 3KP0A 5AQZA 3QFUA 1JZBA 4CQKA 1MR4A 1OZZA
chains in the Genus database with same CATH topology
2N66A 2B68A 1FH3A 1I6FA 2KYQA 1OMYA 1ZFUA 1ZU3A 1TI5A 2LY5A 1LQHA 1DQ7A 1ZVGA 1ZYWA 2N2QA 1DJTA 2GL1A 1AHOA 1NRAA 4HE7A 1ZVEA 2KGQA 2E0HA 4AAZA 1PTXA 1WT7A 1ZYVA 2LT8A 4AB0A 4V1DC 1I2VA 1KV0A 5KK4A 3E7UX 2KJAA 1MYNA 1L4VA 2BRZA 3E7RL 1LQQA 4UJ0A 2NY8X 3PSMA 1NE5A 2LJMA 2MZ0A 1WWNA 2LJ7A 1BRZA 1T1TA 2E3GA 1C56A 2SN3A 2ASCA 2KBJA 4AEIA 2I61A 1ZUTA 1T0ZA 1JXCA 1JKZA 2NY9X 2YC1C 1PE4A 2KBHA 4KYPA 2M8BB 1AYJA 2B3CA 1SN1A 1T7AA 1T7BA 1BMRA 1VNBA 1I2UA 1BCGA 1GPTA 2LY6A 2YBRC 1P00A 1B3CA 1SEGA 2YEOA 1I6GA 2KBKA 2A7TA 1T7EA 5CY0A 2N2RA 1NRBA 1C55A 1B7DA 1N4NA 1VNAA 2E3FA 1BK8A 1GPSA 1CHZA 1ICAA 2KSKA 1PX9A 2LKBA 1SN4A 1WMTA 1SNBA 2LI7A 1LQIA 1P0AA 1NH5A 2KPYA 1NPIA 2N69A 4HHFA 1JZAA 2LR3A 2ATBA 4CQKA 1JZBA 1CN2A 1MR4A 1OZZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N66 A;  2B68 A;  1FH3 A;  1I6F A;  2KYQ A;  1OMY A;  1ZFU A;  1ZU3 A;  1TI5 A;  2LY5 A;  1LQH A;  1DQ7 A;  1ZVG A;  1ZYW A;  2N2Q A;  1DJT A;  2GL1 A;  1AHO A;  1NRA A;  4HE7 A;  1ZVE A;  2KGQ A;  2E0H A;  4AAZ A;  1PTX A;  1WT7 A;  1ZYV A;  2LT8 A;  4AB0 A;  4V1D C;  1I2V A;  1KV0 A;  5KK4 A;  3E7U X;  2KJA A;  1MYN A;  1L4V A;  2BRZ A;  3E7R L;  1LQQ A;  4UJ0 A;  2NY8 X;  3PSM A;  1NE5 A;  2LJM A;  2MZ0 A;  1WWN A;  2LJ7 A;  1BRZ A;  1T1T A;  2E3G A;  1C56 A;  2SN3 A;  2ASC A;  2KBJ A;  4AEI A;  2I61 A;  1ZUT A;  1T0Z A;  1JXC A;  1JKZ A;  2NY9 X;  2YC1 C;  1PE4 A;  2KBH A;  4KYP A;  2M8B B;  1AYJ A;  2B3C A;  1SN1 A;  1T7A A;  1T7B A;  1BMR A;  1VNB A;  1I2U A;  1BCG A;  1GPT A;  2LY6 A;  2YBR C;  1P00 A;  1B3C A;  1SEG A;  2YEO A;  1I6G A;  2KBK A;  2A7T A;  1T7E A;  5CY0 A;  2N2R A;  1NRB A;  1C55 A;  1B7D A;  1N4N A;  1VNA A;  2E3F A;  1BK8 A;  1GPS A;  1CHZ A;  1ICA A;  2KSK A;  1PX9 A;  2LKB A;  1SN4 A;  1WMT A;  1SNB A;  2LI7 A;  1LQI A;  1P0A A;  1NH5 A;  2KPY A;  1NPI A;  2N69 A;  4HHF A;  1JZA A;  2LR3 A;  2ATB A;  4CQK A;  1JZB A;  1CN2 A;  1MR4 A;  1OZZ A; 
#chains in the Genus database with same CATH topology
 2N66 A;  1YUW A;  2B68 A;  4UAF E;  3SF4 D;  1FH3 A;  3KP1 A;  1I6F A;  5AQP A;  2KYQ A;  1OMY A;  2KHO A;  2D56 A;  2QWN A;  2QWR A;  2QWQ A;  1ZFU A;  2YIP A;  5AQH A;  1ZU3 A;  3C7N A;  5EY4 A;  1TI5 A;  2LY5 A;  1NGG A;  1LQH A;  1DQ7 A;  1ZVG A;  1NGF A;  1NGJ A;  2YIL A;  1ZYW A;  1NGI A;  4UAD E;  2N2Q A;  1DJT A;  2GL1 A;  5BPN A;  2QXL A;  3GKU A;  3KVG A;  4FL9 A;  2K35 A;  1AHO A;  1NRA A;  4HE7 A;  1ZVE A;  3AY9 A;  2KGQ A;  2QWO A;  3KC6 A;  5AQJ A;  1NGA A;  2E0H A;  1NGC A;  1S3X A;  3FZM A;  4AAZ A;  1PTX A;  4H5R A;  3D2F A;  3KHW A;  1I2V A;  1WT7 A;  1KAX A;  5AQY A;  1ZYV A;  3A8Y A;  2LT8 A;  1XRS B;  4V1D C;  1UGL A;  1KV0 A;  3QML A;  4AB0 A;  5KK4 A;  3E7U X;  3M3Z A;  5BN9 A;  2KJA A;  3QI7 A;  1MYN A;  2QWM A;  1L4V A;  2JDQ D;  3LDQ A;  2BRZ A;  4FSV A;  3E7R L;  1LQQ A;  3HSC A;  3LDO A;  5AQG A;  4UJ0 A;  5AQQ A;  2NY8 X;  3L6Q A;  3PSM A;  3GL1 A;  1NE5 A;  3JXU A;  2E88 A;  2LJM A;  1WWN A;  2MZ0 A;  3LDN A;  2LJ7 A;  5AQV A;  3D2E A;  2MBK A;  1BA0 A;  1NGH A;  3C7N B;  5AQK A;  5AQN A;  5EVZ A;  2LN8 A;  1T1T A;  5AQW A;  5F2R A;  2E3G A;  1C56 A;  2SN3 A;  1DKG D;  2ASC A;  3CQX A;  2KBJ A;  3QFP A;  5AQR A;  4HWI A;  3FZF A;  2QW9 A;  5AQM A;  5AQT A;  2I61 A;  2QWP A;  1ZUT A;  3KOY A;  4GNI A;  4AEI A;  1T0Z A;  1JXC A;  3ATU A;  1JKZ A;  2NY9 X;  2YC1 C;  1PE4 A;  2KBH A;  2YIO A;  1BUP A;  4KYP A;  2QWL A;  5AQF A;  5FPN A;  2M8B B;  1AYJ A;  5AQL A;  5FPD A;  2B3C A;  1SN1 A;  2GMO A;  1T7A A;  1T7B A;  3CW4 A;  3R2V A;  1BMR A;  3D2F B;  5AQX A;  1VNB A;  1I2U A;  1BCG A;  1BRZ A;  3FE1 A;  1GPT A;  2LY6 A;  2YBR C;  5EX5 A;  4H5N A;  4UAE F;  1P00 A;  1ATS A;  5F1X A;  1HJO A;  5AQI A;  1B3C A;  1SEG A;  2YEO A;  4IO8 A;  2KBK A;  1I6G A;  3L56 A;  2A7T A;  1ATR A;  1T7E A;  5CY0 A;  2G2K A;  3IUC A;  5AQO A;  2N2R A;  3KOW A;  1NRB A;  4KBO A;  1CN2 A;  5AR0 A;  2VY6 A;  1C55 A;  1NGE A;  1NGD A;  1B7D A;  1N4N A;  1VNA A;  3ATV A;  1K8B A;  3D2E B;  1POI A;  1NGB A;  2E3F A;  5AQS A;  5EXW A;  1BK8 A;  1GPS A;  1CHZ A;  1ICA A;  2MN5 A;  3KOZ A;  5AQU A;  1PX9 A;  2KSK A;  2LKB A;  1KAY A;  1QQM A;  1SN4 A;  5F0X A;  2BUP A;  5BN8 A;  3FZK A;  1WMT A;  1SNB A;  2LI7 A;  1LQI A;  3GDQ A;  1P0A A;  3KOX A;  5FPM A;  3L4I A;  1QQO A;  5FPE A;  2V7Z A;  1NH5 A;  1KAZ A;  3LDL A;  4H5T A;  4H5V A;  2KPY A;  2E8A A;  3BK3 C;  3FZH A;  5BPM A;  1BA1 A;  2E2F A;  3LDP A;  1NPI A;  1HX1 A;  2N69 A;  4HHF A;  1JZA A;  4H5W A;  3I33 A;  2LR3 A;  3FZL A;  1HPM A;  2ATB A;  1QQN A;  5BPL A;  3KP0 A;  5AQZ A;  3QFU A;  1JZB A;  4CQK A;  1MR4 A;  1OZZ A; 
#chains in the Genus database with same CATH homology
 2N66 A;  2B68 A;  1FH3 A;  1I6F A;  2KYQ A;  1OMY A;  1ZFU A;  1ZU3 A;  1TI5 A;  2LY5 A;  1LQH A;  1DQ7 A;  1ZVG A;  1ZYW A;  2N2Q A;  1DJT A;  2GL1 A;  1AHO A;  1NRA A;  4HE7 A;  1ZVE A;  2KGQ A;  2E0H A;  4AAZ A;  1PTX A;  1WT7 A;  1ZYV A;  2LT8 A;  4AB0 A;  4V1D C;  1I2V A;  1KV0 A;  5KK4 A;  3E7U X;  2KJA A;  1MYN A;  1L4V A;  2BRZ A;  3E7R L;  1LQQ A;  4UJ0 A;  2NY8 X;  3PSM A;  1NE5 A;  2LJM A;  2MZ0 A;  1WWN A;  2LJ7 A;  1BRZ A;  1T1T A;  2E3G A;  1C56 A;  2SN3 A;  2ASC A;  2KBJ A;  4AEI A;  2I61 A;  1ZUT A;  1T0Z A;  1JXC A;  1JKZ A;  2NY9 X;  2YC1 C;  1PE4 A;  2KBH A;  4KYP A;  2M8B B;  1AYJ A;  2B3C A;  1SN1 A;  1T7A A;  1T7B A;  1BMR A;  1VNB A;  1I2U A;  1BCG A;  1GPT A;  2LY6 A;  2YBR C;  1P00 A;  1B3C A;  1SEG A;  2YEO A;  1I6G A;  2KBK A;  2A7T A;  1T7E A;  5CY0 A;  2N2R A;  1NRB A;  1C55 A;  1B7D A;  1N4N A;  1VNA A;  2E3F A;  1BK8 A;  1GPS A;  1CHZ A;  1ICA A;  2KSK A;  1PX9 A;  2LKB A;  1SN4 A;  1WMT A;  1SNB A;  2LI7 A;  1LQI A;  1P0A A;  1NH5 A;  2KPY A;  1NPI A;  2N69 A;  4HHF A;  1JZA A;  2LR3 A;  2ATB A;  4CQK A;  1JZB A;  1CN2 A;  1MR4 A;  1OZZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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