2E3GA

Nmr structure of def-daa, a mutant of anopheles defensin def-aaa
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
40
structure length
40
Chain Sequence
ATCDLASKWNWNHTLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords defensin, mutant DEF-DAA
publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
source organism Anopheles gambiae
molecule tags Antimicrobial protein
total genus 4
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3gA00
1B3CA 1WMTA 1T0ZA 4AB0A 1L4VA 2YC1C 3E7RL 1ICAA 1GPTA 2LT8A 2M8BB 1ZYVA 1BRZA 1OZZA 1T7AA 1SN1A 1C56A 1VNAA 4V1DC 5KK4A 1BCGA 2B68A 1P0AA 1LQIA 1I2UA 2LJ7A 1ZVEA 1NH5A 1LQHA 2MZ0A 1AYJA 1DQ7A 1DJTA 2N66A 1C55A 1CHZA 1VNBA 2KBHA 2B3CA 1BMRA 1ZFUA 1SEGA 1PTXA 1PX9A 1ZVGA 1BK8A 2ATBA 2LY6A 1ZUTA 4CQKA 1TI5A 3E7UX 1CN2A 1SN4A 1PE4A 2NY8X 2KGQA 2KSKA 2KBJA 2BRZA 4HE7A 2E3GA 1T7EA 2YEOA 2LI7A 2LJMA 1WWNA 1N4NA 1I2VA 2KBKA 1NRAA 4UJ0A 1MYNA 1ZYWA 1NE5A 1LQQA 5CY0A 2NY9X 1I6GA 2GL1A 2ASCA 4KYPA 2LKBA 1MR4A 1JKZA 2A7TA 2I61A 2KPYA 3PSMA 1FH3A 1JZAA 1T7BA 1WT7A 2LR3A 1I6FA 1ZU3A 1SNBA 2LY5A 1B7DA 1T1TA 2KJAA 1AHOA 1P00A 2KYQA 1GPSA 2E3FA 2N2QA 4AEIA 2E0HA 4AAZA 1KV0A 2N69A 1JZBA 1OMYA 2N2RA 1NPIA 1NRBA 2YBRC 2SN3A 4HHFA 1JXCA
chains in the Genus database with same CATH superfamily
3ATVA 1WMTA 3L6QA 1B3CA 1T0ZA 1XRSB 4AB0A 3IUCA 1L4VA 2YC1C 3ATUA 5AQWA 3E7RL 3M3ZA 1ICAA 1GPTA 5F1XA 2LT8A 2M8BB 2JDQD 5EVZA 1HPMA 1ZYVA 1ATSA 1OZZA 3QFUA 2GMOA 1NGJA 2YIOA 2QWMA 3KOWA 1T7AA 1SN1A 3LDNA 1C56A 5AQZA 1VNAA 4UAFE 3QMLA 4V1DC 5KK4A 1K8BA 2E2FA 1BCGA 2V7ZA 3R2VA 2QWLA 2B68A 2G2KA 1P0AA 1DKGD 2QWQA 2QWRA 3AY9A 1LQIA 5FPNA 2LJ7A 1NGBA 1BRZA 3FZMA 2E88A 2VY6A 1I2UA 3KOXA 1ZVEA 3KVGA 3LDLA 1NH5A 5AQRA 1LQHA 5BPNA 1NGEA 2MZ0A 2QWPA 3FZHA 1AYJA 1DQ7A 3D2FA 1DJTA 3D2EB 1QQOA 4H5TA 2N66A 1C55A 5AQIA 1CHZA 5AQOA 3KP0A 1VNBA 2KBHA 5BPLA 3L4IA 4H5NA 1BA0A 2B3CA 1BMRA 2QW9A 5AQNA 5AQVA 1ZFUA 1SEGA 1PTXA 3GL1A 3LDOA 1PX9A 1ZVGA 1BK8A 1NGAA 4FSVA 1KAXA 2ATBA 2BUPA 2LY6A 2KHOA 3FZLA 1ZUTA 2QWOA 4CQKA 2YIPA 3KOYA 1TI5A 2K35A 5EXWA 3I33A 3E7UX 1CN2A 5AQHA 1KAYA 1SN4A 2QXLA 1PE4A 3CQXA 2NY8X 5F0XA 1HJOA 3SF4D 2KGQA 2KSKA 3D2EA 5AQYA 1NGFA 2KBJA 2MBKA 5AQKA 3C7NB 2BRZA 5FPDA 3CW4A 4HE7A 2E3GA 1T7EA 2MN5A 2YEOA 3KC6A 1KAZA 3GKUA 2LI7A 2LJMA 1S3XA 1WWNA 5AQTA 5BN8A 5BPMA 1N4NA 5AQPA 1I2VA 1ATRA 2KBKA 1NRAA 5EY4A 3KHWA 4GNIA 4UJ0A 5AR0A 1MYNA 4HWIA 5AQLA 1QQNA 5AQJA 1ZYWA 1NE5A 4H5RA 1LQQA 2LN8A 3FZFA 5CY0A 1QQMA 1NGHA 2NY9X 5AQUA 1I6GA 5EX5A 2GL1A 2ASCA 2D56A 1NGDA 5FPEA 4KYPA 4KBOA 2LKBA 3GDQA 3QI7A 4H5WA 3A8YA 1MR4A 1UGLA 2A7TA 2YILA 3QFPA 4FL9A 1JKZA 4H5VA 5F2RA 2QWNA 2I61A 1BUPA 3LDPA 2KPYA 1HX1A 3JXUA 3PSMA 1JZAA 2E8AA 5AQSA 1T7BA 1WT7A 1FH3A 3HSCA 2LR3A 1I6FA 1ZU3A 1SNBA 3C7NA 5AQMA 2LY5A 4IO8A 1B7DA 1YUWA 1T1TA 2KJAA 1AHOA 1P00A 1POIA 5AQFA 5AQQA 5AQXA 2KYQA 3KP1A 1GPSA 2E3FA 2N2QA 5AQGA 3L56A 4AEIA 1NGGA 2E0HA 4AAZA 1KV0A 5BN9A 2N69A 3KOZA 5FPMA 1JZBA 1OMYA 2N2RA 3FE1A 1BA1A 1NGIA 4UAEF 3BK3C 1NPIA 1NRBA 2YBRC 3FZKA 2SN3A 4HHFA 3D2FB 1NGCA 1JXCA 4UADE 3LDQA
chains in the Genus database with same CATH topology
1B3CA 1WMTA 1T0ZA 4AB0A 1L4VA 2YC1C 3E7RL 1ICAA 1GPTA 2LT8A 2M8BB 1ZYVA 1BRZA 1OZZA 1T7AA 1SN1A 1C56A 1VNAA 4V1DC 5KK4A 1BCGA 2B68A 1P0AA 1LQIA 1I2UA 2LJ7A 1ZVEA 1NH5A 1LQHA 2MZ0A 1AYJA 1DQ7A 1DJTA 2N66A 1C55A 1CHZA 1VNBA 2KBHA 2B3CA 1BMRA 1ZFUA 1SEGA 1PTXA 1PX9A 1ZVGA 1BK8A 2ATBA 2LY6A 1ZUTA 4CQKA 1TI5A 3E7UX 1CN2A 1SN4A 1PE4A 2NY8X 2KGQA 2KSKA 2KBJA 2BRZA 4HE7A 2E3GA 1T7EA 2YEOA 2LI7A 2LJMA 1WWNA 1N4NA 1I2VA 2KBKA 1NRAA 4UJ0A 1MYNA 1ZYWA 1NE5A 1LQQA 5CY0A 2NY9X 1I6GA 2GL1A 2ASCA 4KYPA 2LKBA 1MR4A 1JKZA 2A7TA 2I61A 2KPYA 3PSMA 1FH3A 1JZAA 1T7BA 1WT7A 2LR3A 1I6FA 1ZU3A 1SNBA 2LY5A 1B7DA 1T1TA 2KJAA 1AHOA 1P00A 2KYQA 1GPSA 2E3FA 2N2QA 4AEIA 2E0HA 4AAZA 1KV0A 2N69A 1JZBA 1OMYA 2N2RA 1NPIA 1NRBA 2YBRC 2SN3A 4HHFA 1JXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B3C A;  1WMT A;  1T0Z A;  4AB0 A;  1L4V A;  2YC1 C;  3E7R L;  1ICA A;  1GPT A;  2LT8 A;  2M8B B;  1ZYV A;  1BRZ A;  1OZZ A;  1T7A A;  1SN1 A;  1C56 A;  1VNA A;  4V1D C;  5KK4 A;  1BCG A;  2B68 A;  1P0A A;  1LQI A;  1I2U A;  2LJ7 A;  1ZVE A;  1NH5 A;  1LQH A;  2MZ0 A;  1AYJ A;  1DQ7 A;  1DJT A;  2N66 A;  1C55 A;  1CHZ A;  1VNB A;  2KBH A;  2B3C A;  1BMR A;  1ZFU A;  1SEG A;  1PTX A;  1PX9 A;  1ZVG A;  1BK8 A;  2ATB A;  2LY6 A;  1ZUT A;  4CQK A;  1TI5 A;  3E7U X;  1CN2 A;  1SN4 A;  1PE4 A;  2NY8 X;  2KGQ A;  2KSK A;  2KBJ A;  2BRZ A;  4HE7 A;  2E3G A;  1T7E A;  2YEO A;  2LI7 A;  2LJM A;  1WWN A;  1N4N A;  1I2V A;  2KBK A;  1NRA A;  4UJ0 A;  1MYN A;  1ZYW A;  1NE5 A;  1LQQ A;  5CY0 A;  2NY9 X;  1I6G A;  2GL1 A;  2ASC A;  4KYP A;  2LKB A;  1MR4 A;  1JKZ A;  2A7T A;  2I61 A;  2KPY A;  3PSM A;  1FH3 A;  1JZA A;  1T7B A;  1WT7 A;  2LR3 A;  1I6F A;  1ZU3 A;  1SNB A;  2LY5 A;  1B7D A;  1T1T A;  2KJA A;  1AHO A;  1P00 A;  2KYQ A;  1GPS A;  2E3F A;  2N2Q A;  4AEI A;  2E0H A;  4AAZ A;  1KV0 A;  2N69 A;  1JZB A;  1OMY A;  2N2R A;  1NPI A;  1NRB A;  2YBR C;  2SN3 A;  4HHF A;  1JXC A; 
#chains in the Genus database with same CATH topology
 3ATV A;  1WMT A;  3L6Q A;  1B3C A;  1T0Z A;  1XRS B;  4AB0 A;  3IUC A;  1L4V A;  2YC1 C;  3ATU A;  5AQW A;  3E7R L;  3M3Z A;  1ICA A;  1GPT A;  5F1X A;  2LT8 A;  2M8B B;  2JDQ D;  5EVZ A;  1HPM A;  1ZYV A;  1ATS A;  1OZZ A;  3QFU A;  2GMO A;  1NGJ A;  2YIO A;  2QWM A;  3KOW A;  1T7A A;  1SN1 A;  3LDN A;  1C56 A;  5AQZ A;  1VNA A;  4UAF E;  3QML A;  4V1D C;  5KK4 A;  1K8B A;  2E2F A;  1BCG A;  2V7Z A;  3R2V A;  2QWL A;  2B68 A;  2G2K A;  1P0A A;  1DKG D;  2QWQ A;  2QWR A;  3AY9 A;  1LQI A;  5FPN A;  2LJ7 A;  1NGB A;  1BRZ A;  3FZM A;  2E88 A;  2VY6 A;  1I2U A;  3KOX A;  1ZVE A;  3KVG A;  3LDL A;  1NH5 A;  5AQR A;  1LQH A;  5BPN A;  1NGE A;  2MZ0 A;  2QWP A;  3FZH A;  1AYJ A;  1DQ7 A;  3D2F A;  1DJT A;  3D2E B;  1QQO A;  4H5T A;  2N66 A;  1C55 A;  5AQI A;  1CHZ A;  5AQO A;  3KP0 A;  1VNB A;  2KBH A;  5BPL A;  3L4I A;  4H5N A;  1BA0 A;  2B3C A;  1BMR A;  2QW9 A;  5AQN A;  5AQV A;  1ZFU A;  1SEG A;  1PTX A;  3GL1 A;  3LDO A;  1PX9 A;  1ZVG A;  1BK8 A;  1NGA A;  4FSV A;  1KAX A;  2ATB A;  2BUP A;  2LY6 A;  2KHO A;  3FZL A;  1ZUT A;  2QWO A;  4CQK A;  2YIP A;  3KOY A;  1TI5 A;  2K35 A;  5EXW A;  3I33 A;  3E7U X;  1CN2 A;  5AQH A;  1KAY A;  1SN4 A;  2QXL A;  1PE4 A;  3CQX A;  2NY8 X;  5F0X A;  1HJO A;  3SF4 D;  2KGQ A;  2KSK A;  3D2E A;  5AQY A;  1NGF A;  2KBJ A;  2MBK A;  5AQK A;  3C7N B;  2BRZ A;  5FPD A;  3CW4 A;  4HE7 A;  2E3G A;  1T7E A;  2MN5 A;  2YEO A;  3KC6 A;  1KAZ A;  3GKU A;  2LI7 A;  2LJM A;  1S3X A;  1WWN A;  5AQT A;  5BN8 A;  5BPM A;  1N4N A;  5AQP A;  1I2V A;  1ATR A;  2KBK A;  1NRA A;  5EY4 A;  3KHW A;  4GNI A;  4UJ0 A;  5AR0 A;  1MYN A;  4HWI A;  5AQL A;  1QQN A;  5AQJ A;  1ZYW A;  1NE5 A;  4H5R A;  1LQQ A;  2LN8 A;  3FZF A;  5CY0 A;  1QQM A;  1NGH A;  2NY9 X;  5AQU A;  1I6G A;  5EX5 A;  2GL1 A;  2ASC A;  2D56 A;  1NGD A;  5FPE A;  4KYP A;  4KBO A;  2LKB A;  3GDQ A;  3QI7 A;  4H5W A;  3A8Y A;  1MR4 A;  1UGL A;  2A7T A;  2YIL A;  3QFP A;  4FL9 A;  1JKZ A;  4H5V A;  5F2R A;  2QWN A;  2I61 A;  1BUP A;  3LDP A;  2KPY A;  1HX1 A;  3JXU A;  3PSM A;  1JZA A;  2E8A A;  5AQS A;  1T7B A;  1WT7 A;  1FH3 A;  3HSC A;  2LR3 A;  1I6F A;  1ZU3 A;  1SNB A;  3C7N A;  5AQM A;  2LY5 A;  4IO8 A;  1B7D A;  1YUW A;  1T1T A;  2KJA A;  1AHO A;  1P00 A;  1POI A;  5AQF A;  5AQQ A;  5AQX A;  2KYQ A;  3KP1 A;  1GPS A;  2E3F A;  2N2Q A;  5AQG A;  3L56 A;  4AEI A;  1NGG A;  2E0H A;  4AAZ A;  1KV0 A;  5BN9 A;  2N69 A;  3KOZ A;  5FPM A;  1JZB A;  1OMY A;  2N2R A;  3FE1 A;  1BA1 A;  1NGI A;  4UAE F;  3BK3 C;  1NPI A;  1NRB A;  2YBR C;  3FZK A;  2SN3 A;  4HHF A;  3D2F B;  1NGC A;  1JXC A;  4UAD E;  3LDQ A; 
#chains in the Genus database with same CATH homology
 1B3C A;  1WMT A;  1T0Z A;  4AB0 A;  1L4V A;  2YC1 C;  3E7R L;  1ICA A;  1GPT A;  2LT8 A;  2M8B B;  1ZYV A;  1BRZ A;  1OZZ A;  1T7A A;  1SN1 A;  1C56 A;  1VNA A;  4V1D C;  5KK4 A;  1BCG A;  2B68 A;  1P0A A;  1LQI A;  1I2U A;  2LJ7 A;  1ZVE A;  1NH5 A;  1LQH A;  2MZ0 A;  1AYJ A;  1DQ7 A;  1DJT A;  2N66 A;  1C55 A;  1CHZ A;  1VNB A;  2KBH A;  2B3C A;  1BMR A;  1ZFU A;  1SEG A;  1PTX A;  1PX9 A;  1ZVG A;  1BK8 A;  2ATB A;  2LY6 A;  1ZUT A;  4CQK A;  1TI5 A;  3E7U X;  1CN2 A;  1SN4 A;  1PE4 A;  2NY8 X;  2KGQ A;  2KSK A;  2KBJ A;  2BRZ A;  4HE7 A;  2E3G A;  1T7E A;  2YEO A;  2LI7 A;  2LJM A;  1WWN A;  1N4N A;  1I2V A;  2KBK A;  1NRA A;  4UJ0 A;  1MYN A;  1ZYW A;  1NE5 A;  1LQQ A;  5CY0 A;  2NY9 X;  1I6G A;  2GL1 A;  2ASC A;  4KYP A;  2LKB A;  1MR4 A;  1JKZ A;  2A7T A;  2I61 A;  2KPY A;  3PSM A;  1FH3 A;  1JZA A;  1T7B A;  1WT7 A;  2LR3 A;  1I6F A;  1ZU3 A;  1SNB A;  2LY5 A;  1B7D A;  1T1T A;  2KJA A;  1AHO A;  1P00 A;  2KYQ A;  1GPS A;  2E3F A;  2N2Q A;  4AEI A;  2E0H A;  4AAZ A;  1KV0 A;  2N69 A;  1JZB A;  1OMY A;  2N2R A;  1NPI A;  1NRB A;  2YBR C;  2SN3 A;  4HHF A;  1JXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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