1CN2A

Solution structure of toxin 2 from centruroides noxius hoffmann, a beta scorpion neurotoxin acting on sodium channels, nmr, 15 structures
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
pubmed doi rcsb
molecule tags Neurotoxin
molecule keywords TOXIN 2
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 1998-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1cn2A00
1GPSA 1ZVGA 1MYNA 1I6GA 1KV0A 2MZ0A 1NRBA 1DJTA 2NY9X 2B3CA 2BRZA 2N2RA 2A7TA 1PTXA 1CN2A 3E7UX 1T7AA 2E3FA 2LI7A 1NPIA 1ZVEA 1BCGA 2KBJA 4HE7A 1B3CA 1OZZA 1T7EA 1BK8A 4CQKA 4KYPA 2LY5A 1C56A 1P00A 1C55A 1AHOA 1ICAA 1T0ZA 2KBHA 2KSKA 2N69A 1SN1A 1P0AA 1JZBA 2LY6A 2I61A 2GL1A 5KK4A 4HHFA 2YEOA 2M8BB 2E0HA 2KJAA 1ZYWA 1AYJA 1I6FA 1I2VA 1N4NA 1T1TA 1JXCA 1ZUTA 1ZU3A 2KYQA 1JKZA 1FH3A 1LQIA 2YBRC 1NE5A 4UJ0A 2LKBA 2ATBA 1T7BA 1PX9A 1DQ7A 4AEIA 2SN3A 1ZYVA 2B68A 2N66A 1OMYA 1VNAA 1SNBA 1TI5A 4AB0A 1BMRA 1SEGA 1WT7A 1MR4A 2NY8X 1SN4A 1I2UA 2KGQA 1CHZA 4AAZA 1BRZA 3E7RL 2E3GA 5CY0A 1WWNA 1ZFUA 2LT8A 2ASCA 1LQQA 2N2QA 3PSMA 2YC1C 1B7DA 2LR3A 2KPYA 1GPTA 1PE4A 1JZAA 1LQHA 2LJMA 1L4VA 2KBKA 4V1DC 1WMTA 1VNBA 1NRAA 2LJ7A 1NH5A
chains in the Genus database with same CATH superfamily
3QI7A 1GPSA 5AQSA 3SF4D 1ZVGA 2G2KA 1MYNA 1I6GA 1KV0A 2MZ0A 1NRBA 1DJTA 2NY9X 1KAZA 2B3CA 5AQRA 1BA0A 4IO8A 2BRZA 2N2RA 3LDPA 5AQUA 2A7TA 1PTXA 1CN2A 3E7UX 3D2EB 1DKGD 1T7AA 3L6QA 2E3FA 3A8YA 2E2FA 2LI7A 3LDNA 1POIA 3CW4A 1NPIA 1HPMA 1ZVEA 1BCGA 2KBJA 5AQVA 4HE7A 1B3CA 1OZZA 1T7EA 1BK8A 4CQKA 4KYPA 2LY5A 3FZMA 5AQGA 3QMLA 5EY4A 5BN9A 3D2FB 1C56A 3KOZA 4UAEF 1P00A 1C55A 2K35A 5FPNA 1AHOA 1ICAA 2YILA 1T0ZA 2KBHA 2V7ZA 2KSKA 5BN8A 2N69A 1SN1A 5EXWA 2QWMA 1P0AA 3FE1A 3KP1A 2D56A 5BPLA 3JXUA 1JZBA 1QQOA 2LY6A 2I61A 5FPDA 3BK3C 2E88A 3LDOA 5AQKA 2GL1A 2YIPA 3C7NA 2QWPA 1K8BA 3KOXA 5AQWA 5KK4A 4HHFA 1NGCA 1NGJA 1NGHA 2YEOA 2M8BB 3FZLA 2E0HA 3KOWA 2KJAA 5BPMA 5AQJA 5AQQA 1ZYWA 1KAYA 3FZHA 1AYJA 3KC6A 1I6FA 2QXLA 2MN5A 1I2VA 1N4NA 1T1TA 1JXCA 1ZUTA 1ZU3A 2KHOA 5AQFA 2KYQA 1JKZA 1FH3A 3D2EA 1LQIA 2YBRC 1NE5A 3ATVA 3KVGA 5F2RA 3ATUA 5EVZA 4FSVA 4UJ0A 2LKBA 4H5NA 3LDQA 4UADE 2ATBA 1T7BA 3KHWA 3KOYA 4HWIA 5AQNA 1PX9A 4GNIA 1DQ7A 4AEIA 1HJOA 3D2FA 2SN3A 1ZYVA 2B68A 2N66A 5F0XA 1OMYA 1QQMA 3R2VA 1HX1A 3L4IA 5FPEA 1VNAA 3QFUA 5AQHA 1SNBA 5AR0A 1UGLA 1TI5A 5AQPA 5FPMA 1S3XA 5AQLA 4AB0A 2GMOA 3CQXA 1BMRA 4H5RA 1SEGA 1WT7A 1MR4A 2MBKA 2NY8X 1SN4A 2QW9A 5AQOA 2VY6A 2QWOA 1I2UA 2KGQA 1CHZA 1NGFA 1NGDA 2QWNA 3I33A 1NGAA 4H5WA 5AQIA 5AQYA 4AAZA 1BRZA 5AQZA 1NGBA 1NGGA 2QWLA 3E7RL 2E3GA 3LDLA 4KBOA 5CY0A 3KP0A 2QWRA 3HSCA 3M3ZA 4H5TA 1WWNA 1ZFUA 5AQXA 1QQNA 2LT8A 3FZFA 2ASCA 1LQQA 4UAFE 5AQMA 2N2QA 3PSMA 1YUWA 2E8AA 2LN8A 2YC1C 1XRSB 2BUPA 1B7DA 2LR3A 5EX5A 1NGIA 2KPYA 2QWQA 1GPTA 1PE4A 1JZAA 3GDQA 3QFPA 5BPNA 3GKUA 1LQHA 2LJMA 4H5VA 1L4VA 1BUPA 2KBKA 3GL1A 4V1DC 1KAXA 1WMTA 1VNBA 1NRAA 2JDQD 3IUCA 5AQTA 4FL9A 3C7NB 2YIOA 1NGEA 2LJ7A 1ATSA 3L56A 3AY9A 3FZKA 1NH5A 1ATRA 5F1XA 1BA1A
chains in the Genus database with same CATH topology
1GPSA 1ZVGA 1MYNA 1I6GA 1KV0A 2MZ0A 1NRBA 1DJTA 2NY9X 2B3CA 2BRZA 2N2RA 2A7TA 1PTXA 1CN2A 3E7UX 1T7AA 2E3FA 2LI7A 1NPIA 1ZVEA 1BCGA 2KBJA 4HE7A 1B3CA 1OZZA 1T7EA 1BK8A 4CQKA 4KYPA 2LY5A 1C56A 1P00A 1C55A 1AHOA 1ICAA 1T0ZA 2KBHA 2KSKA 2N69A 1SN1A 1P0AA 1JZBA 2LY6A 2I61A 2GL1A 5KK4A 4HHFA 2YEOA 2M8BB 2E0HA 2KJAA 1ZYWA 1AYJA 1I6FA 1I2VA 1N4NA 1T1TA 1JXCA 1ZUTA 1ZU3A 2KYQA 1JKZA 1FH3A 1LQIA 2YBRC 1NE5A 4UJ0A 2LKBA 2ATBA 1T7BA 1PX9A 1DQ7A 4AEIA 2SN3A 1ZYVA 2B68A 2N66A 1OMYA 1VNAA 1SNBA 1TI5A 4AB0A 1BMRA 1SEGA 1WT7A 1MR4A 2NY8X 1SN4A 1I2UA 2KGQA 1CHZA 4AAZA 1BRZA 3E7RL 2E3GA 5CY0A 1WWNA 1ZFUA 2LT8A 2ASCA 1LQQA 2N2QA 3PSMA 2YC1C 1B7DA 2LR3A 2KPYA 1GPTA 1PE4A 1JZAA 1LQHA 2LJMA 1L4VA 2KBKA 4V1DC 1WMTA 1VNBA 1NRAA 2LJ7A 1NH5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GPS A;  1ZVG A;  1MYN A;  1I6G A;  1KV0 A;  2MZ0 A;  1NRB A;  1DJT A;  2NY9 X;  2B3C A;  2BRZ A;  2N2R A;  2A7T A;  1PTX A;  1CN2 A;  3E7U X;  1T7A A;  2E3F A;  2LI7 A;  1NPI A;  1ZVE A;  1BCG A;  2KBJ A;  4HE7 A;  1B3C A;  1OZZ A;  1T7E A;  1BK8 A;  4CQK A;  4KYP A;  2LY5 A;  1C56 A;  1P00 A;  1C55 A;  1AHO A;  1ICA A;  1T0Z A;  2KBH A;  2KSK A;  2N69 A;  1SN1 A;  1P0A A;  1JZB A;  2LY6 A;  2I61 A;  2GL1 A;  5KK4 A;  4HHF A;  2YEO A;  2M8B B;  2E0H A;  2KJA A;  1ZYW A;  1AYJ A;  1I6F A;  1I2V A;  1N4N A;  1T1T A;  1JXC A;  1ZUT A;  1ZU3 A;  2KYQ A;  1JKZ A;  1FH3 A;  1LQI A;  2YBR C;  1NE5 A;  4UJ0 A;  2LKB A;  2ATB A;  1T7B A;  1PX9 A;  1DQ7 A;  4AEI A;  2SN3 A;  1ZYV A;  2B68 A;  2N66 A;  1OMY A;  1VNA A;  1SNB A;  1TI5 A;  4AB0 A;  1BMR A;  1SEG A;  1WT7 A;  1MR4 A;  2NY8 X;  1SN4 A;  1I2U A;  2KGQ A;  1CHZ A;  4AAZ A;  1BRZ A;  3E7R L;  2E3G A;  5CY0 A;  1WWN A;  1ZFU A;  2LT8 A;  2ASC A;  1LQQ A;  2N2Q A;  3PSM A;  2YC1 C;  1B7D A;  2LR3 A;  2KPY A;  1GPT A;  1PE4 A;  1JZA A;  1LQH A;  2LJM A;  1L4V A;  2KBK A;  4V1D C;  1WMT A;  1VNB A;  1NRA A;  2LJ7 A;  1NH5 A; 
#chains in the Genus database with same CATH topology
 3QI7 A;  1GPS A;  5AQS A;  3SF4 D;  1ZVG A;  2G2K A;  1MYN A;  1I6G A;  1KV0 A;  2MZ0 A;  1NRB A;  1DJT A;  2NY9 X;  1KAZ A;  2B3C A;  5AQR A;  1BA0 A;  4IO8 A;  2BRZ A;  2N2R A;  3LDP A;  5AQU A;  2A7T A;  1PTX A;  1CN2 A;  3E7U X;  3D2E B;  1DKG D;  1T7A A;  3L6Q A;  2E3F A;  3A8Y A;  2E2F A;  2LI7 A;  3LDN A;  1POI A;  3CW4 A;  1NPI A;  1HPM A;  1ZVE A;  1BCG A;  2KBJ A;  5AQV A;  4HE7 A;  1B3C A;  1OZZ A;  1T7E A;  1BK8 A;  4CQK A;  4KYP A;  2LY5 A;  3FZM A;  5AQG A;  3QML A;  5EY4 A;  5BN9 A;  3D2F B;  1C56 A;  3KOZ A;  4UAE F;  1P00 A;  1C55 A;  2K35 A;  5FPN A;  1AHO A;  1ICA A;  2YIL A;  1T0Z A;  2KBH A;  2V7Z A;  2KSK A;  5BN8 A;  2N69 A;  1SN1 A;  5EXW A;  2QWM A;  1P0A A;  3FE1 A;  3KP1 A;  2D56 A;  5BPL A;  3JXU A;  1JZB A;  1QQO A;  2LY6 A;  2I61 A;  5FPD A;  3BK3 C;  2E88 A;  3LDO A;  5AQK A;  2GL1 A;  2YIP A;  3C7N A;  2QWP A;  1K8B A;  3KOX A;  5AQW A;  5KK4 A;  4HHF A;  1NGC A;  1NGJ A;  1NGH A;  2YEO A;  2M8B B;  3FZL A;  2E0H A;  3KOW A;  2KJA A;  5BPM A;  5AQJ A;  5AQQ A;  1ZYW A;  1KAY A;  3FZH A;  1AYJ A;  3KC6 A;  1I6F A;  2QXL A;  2MN5 A;  1I2V A;  1N4N A;  1T1T A;  1JXC A;  1ZUT A;  1ZU3 A;  2KHO A;  5AQF A;  2KYQ A;  1JKZ A;  1FH3 A;  3D2E A;  1LQI A;  2YBR C;  1NE5 A;  3ATV A;  3KVG A;  5F2R A;  3ATU A;  5EVZ A;  4FSV A;  4UJ0 A;  2LKB A;  4H5N A;  3LDQ A;  4UAD E;  2ATB A;  1T7B A;  3KHW A;  3KOY A;  4HWI A;  5AQN A;  1PX9 A;  4GNI A;  1DQ7 A;  4AEI A;  1HJO A;  3D2F A;  2SN3 A;  1ZYV A;  2B68 A;  2N66 A;  5F0X A;  1OMY A;  1QQM A;  3R2V A;  1HX1 A;  3L4I A;  5FPE A;  1VNA A;  3QFU A;  5AQH A;  1SNB A;  5AR0 A;  1UGL A;  1TI5 A;  5AQP A;  5FPM A;  1S3X A;  5AQL A;  4AB0 A;  2GMO A;  3CQX A;  1BMR A;  4H5R A;  1SEG A;  1WT7 A;  1MR4 A;  2MBK A;  2NY8 X;  1SN4 A;  2QW9 A;  5AQO A;  2VY6 A;  2QWO A;  1I2U A;  2KGQ A;  1CHZ A;  1NGF A;  1NGD A;  2QWN A;  3I33 A;  1NGA A;  4H5W A;  5AQI A;  5AQY A;  4AAZ A;  1BRZ A;  5AQZ A;  1NGB A;  1NGG A;  2QWL A;  3E7R L;  2E3G A;  3LDL A;  4KBO A;  5CY0 A;  3KP0 A;  2QWR A;  3HSC A;  3M3Z A;  4H5T A;  1WWN A;  1ZFU A;  5AQX A;  1QQN A;  2LT8 A;  3FZF A;  2ASC A;  1LQQ A;  4UAF E;  5AQM A;  2N2Q A;  3PSM A;  1YUW A;  2E8A A;  2LN8 A;  2YC1 C;  1XRS B;  2BUP A;  1B7D A;  2LR3 A;  5EX5 A;  1NGI A;  2KPY A;  2QWQ A;  1GPT A;  1PE4 A;  1JZA A;  3GDQ A;  3QFP A;  5BPN A;  3GKU A;  1LQH A;  2LJM A;  4H5V A;  1L4V A;  1BUP A;  2KBK A;  3GL1 A;  4V1D C;  1KAX A;  1WMT A;  1VNB A;  1NRA A;  2JDQ D;  3IUC A;  5AQT A;  4FL9 A;  3C7N B;  2YIO A;  1NGE A;  2LJ7 A;  1ATS A;  3L56 A;  3AY9 A;  3FZK A;  1NH5 A;  1ATR A;  5F1X A;  1BA1 A; 
#chains in the Genus database with same CATH homology
 1GPS A;  1ZVG A;  1MYN A;  1I6G A;  1KV0 A;  2MZ0 A;  1NRB A;  1DJT A;  2NY9 X;  2B3C A;  2BRZ A;  2N2R A;  2A7T A;  1PTX A;  1CN2 A;  3E7U X;  1T7A A;  2E3F A;  2LI7 A;  1NPI A;  1ZVE A;  1BCG A;  2KBJ A;  4HE7 A;  1B3C A;  1OZZ A;  1T7E A;  1BK8 A;  4CQK A;  4KYP A;  2LY5 A;  1C56 A;  1P00 A;  1C55 A;  1AHO A;  1ICA A;  1T0Z A;  2KBH A;  2KSK A;  2N69 A;  1SN1 A;  1P0A A;  1JZB A;  2LY6 A;  2I61 A;  2GL1 A;  5KK4 A;  4HHF A;  2YEO A;  2M8B B;  2E0H A;  2KJA A;  1ZYW A;  1AYJ A;  1I6F A;  1I2V A;  1N4N A;  1T1T A;  1JXC A;  1ZUT A;  1ZU3 A;  2KYQ A;  1JKZ A;  1FH3 A;  1LQI A;  2YBR C;  1NE5 A;  4UJ0 A;  2LKB A;  2ATB A;  1T7B A;  1PX9 A;  1DQ7 A;  4AEI A;  2SN3 A;  1ZYV A;  2B68 A;  2N66 A;  1OMY A;  1VNA A;  1SNB A;  1TI5 A;  4AB0 A;  1BMR A;  1SEG A;  1WT7 A;  1MR4 A;  2NY8 X;  1SN4 A;  1I2U A;  2KGQ A;  1CHZ A;  4AAZ A;  1BRZ A;  3E7R L;  2E3G A;  5CY0 A;  1WWN A;  1ZFU A;  2LT8 A;  2ASC A;  1LQQ A;  2N2Q A;  3PSM A;  2YC1 C;  1B7D A;  2LR3 A;  2KPY A;  1GPT A;  1PE4 A;  1JZA A;  1LQH A;  2LJM A;  1L4V A;  2KBK A;  4V1D C;  1WMT A;  1VNB A;  1NRA A;  2LJ7 A;  1NH5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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