3BK3C

Crystal structure of the complex of bmp-2 and the first von willebrand domain type c of crossveinless-2
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
67
structure length
67
Chain Sequence
WLITGTEASCENEGEVLHIPNITDNPCISCVCLNQKAECKQEKCAPLAEDCALVVKQTGACCEKCKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 8
structure length 67
sequence length 67
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-12-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.190 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3bk3C00
3BK3C 2MBKA
chains in the Genus database with same CATH superfamily
5AQVA 2YIOA 5AQUA 3JXUA 3M3ZA 5AQTA 3L56A 4FSVA 1ZYVA 2KHOA 5AQOA 2GMOA 3KOXA 1B7DA 3L6QA 5AQMA 1T7EA 2QWNA 3E7RL 1BA1A 1KAZA 1T7BA 2KPYA 4FL9A 1NGAA 2JDQD 3FZHA 5FPEA 3KHWA 3QFUA 2YBRC 5AQRA 1I6GA 4V1DC 4AEIA 1DJTA 1NGDA 2LY5A 1PTXA 2N2QA 1XRSB 3LDLA 2E8AA 1NH5A 3D2FA 2QWRA 5BPLA 2B68A 4AB0A 5AQYA 1OZZA 1ZVGA 5BN9A 2BRZA 2LT8A 1L4VA 1AHOA 4UAEF 3D2EA 1ZFUA 2A7TA 1KV0A 1ZU3A 1BMRA 3QMLA 1N4NA 1JZAA 4HE7A 2NY9X 5EXWA 5F2RA 2M8BB 2KBJA 3KP0A 2E3GA 1HX1A 2KJAA 3A8YA 3D2FB 3I33A 4KYPA 2E2FA 1PX9A 1QQNA 1ATRA 1I6FA 1ATSA 5AQXA 5AQIA 3D2EB 2MBKA 1BCGA 1JXCA 1SEGA 3KOZA 1NGBA 1YUWA 3ATVA 2SN3A 2B3CA 5AQHA 1VNBA 1ZYWA 1T7AA 1KAYA 2K35A 2MZ0A 3AY9A 3C7NA 2QWPA 5AQSA 1NPIA 2LJMA 2ASCA 2LY6A 5AQZA 1I2VA 5BPNA 1WWNA 1NGCA 1NRBA 2KSKA 2N66A 4H5NA 2V7ZA 2N2RA 4H5TA 1S3XA 1BRZA 3KOWA 3QFPA 1B3CA 4H5RA 5AQJA 1CN2A 2YILA 2QWMA 3L4IA 3LDNA 1NGHA 1WMTA 2QWOA 5AQLA 3LDPA 1JZBA 1ZVEA 2YEOA 1HJOA 2BUPA 2QW9A 1K8BA 2LJ7A 1TI5A 3FE1A 5F0XA 5AQPA 3GDQA 1C56A 3GKUA 3GL1A 2LI7A 3FZLA 3KC6A 3KOYA 1KAXA 1UGLA 1MR4A 4HHFA 5BPMA 2N69A 1FH3A 3ATUA 2KGQA 3CW4A 1C55A 1WT7A 4H5WA 3E7UX 1NGJA 3PSMA 2KYQA 3LDOA 5AQGA 4UJ0A 2ATBA 1NE5A 1NGFA 1POIA 1LQHA 1SNBA 2YC1C 3CQXA 3FZFA 5AQWA 5AR0A 5AQQA 2E3FA 1BK8A 3FZKA 5FPMA 2QWQA 3SF4D 2QWLA 1NGEA 4GNIA 2LR3A 4IO8A 2NY8X 5AQFA 5FPNA 5CY0A 1JKZA 1P00A 1QQMA 5F1XA 1SN1A 3C7NB 4HWIA 1P0AA 3LDQA 3HSCA 3KP1A 2E0HA 2D56A 2LKBA 3BK3C 1SN4A 1BA0A 2LN8A 1DKGD 5FPDA 4H5VA 5BN8A 1CHZA 2E88A 2KBKA 1LQQA 4AAZA 5AQKA 5EY4A 1HPMA 1GPSA 4UADE 1MYNA 1NGGA 1T0ZA 3QI7A 4KBOA 1ICAA 1ZUTA 2MN5A 5AQNA 1BUPA 2KBHA 2G2KA 1GPTA 2VY6A 1VNAA 1OMYA 3R2VA 2QXLA 5EX5A 5KK4A 2I61A 2GL1A 4UAFE 1AYJA 1I2UA 3KVGA 1LQIA 1DQ7A 1NRAA 1NGIA 1PE4A 1QQOA 2YIPA 3FZMA 3IUCA 1T1TA 4CQKA 5EVZA
chains in the Genus database with same CATH topology
5AQVA 2YIOA 5AQUA 3JXUA 3M3ZA 5AQTA 3L56A 4FSVA 2KHOA 5AQOA 2GMOA 5AQMA 3L6QA 2QWNA 1BA1A 1KAZA 4FL9A 5FPEA 1NGAA 2JDQD 3FZHA 3KHWA 3QFUA 5AQRA 1NGDA 3LDLA 2E8AA 3D2FA 5BPLA 2QWRA 5AQYA 5BN9A 4UAEF 3D2EA 3QMLA 5EXWA 5F2RA 1HX1A 3A8YA 3D2FB 3I33A 2E2FA 1QQNA 1ATRA 1ATSA 5AQXA 5AQIA 3D2EB 2MBKA 1NGBA 1YUWA 3ATVA 5AQHA 5AQSA 1KAYA 2K35A 3AY9A 3C7NA 5AQZA 2QWPA 5BPNA 1NGCA 4H5NA 2V7ZA 4H5TA 1S3XA 3QFPA 4H5RA 5AQJA 2YILA 2QWMA 3L4IA 3LDNA 1NGHA 2QWOA 5AQLA 3LDPA 1HJOA 2BUPA 2QW9A 3FE1A 5F0XA 5AQPA 3GDQA 3GL1A 3FZLA 3KC6A 1KAXA 5BPMA 3ATUA 3CW4A 4H5WA 1NGJA 3LDOA 5AQGA 5AQWA 1NGFA 1POIA 3CQXA 3FZFA 5AR0A 5AQQA 3FZKA 5FPMA 2QWQA 3SF4D 2QWLA 1NGEA 4GNIA 4IO8A 5AQFA 5FPNA 5F1XA 1QQMA 3C7NB 4HWIA 3LDQA 3HSCA 2D56A 3BK3C 1BA0A 2LN8A 1DKGD 5FPDA 4H5VA 5BN8A 2E88A 5AQKA 5EY4A 1HPMA 4UADE 1NGGA 3QI7A 4KBOA 2MN5A 5AQNA 1BUPA 2VY6A 3R2VA 2QXLA 5EX5A 4UAFE 3KVGA 2YIPA 3FZMA 1QQOA 1NGIA 3IUCA 5EVZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BK3 C;  2MBK A; 
#chains in the Genus database with same CATH topology
 5AQV A;  2YIO A;  5AQU A;  3JXU A;  3M3Z A;  5AQT A;  3L56 A;  4FSV A;  1ZYV A;  2KHO A;  5AQO A;  2GMO A;  3KOX A;  1B7D A;  3L6Q A;  5AQM A;  1T7E A;  2QWN A;  3E7R L;  1BA1 A;  1KAZ A;  1T7B A;  2KPY A;  4FL9 A;  1NGA A;  2JDQ D;  3FZH A;  5FPE A;  3KHW A;  3QFU A;  2YBR C;  5AQR A;  1I6G A;  4V1D C;  4AEI A;  1DJT A;  1NGD A;  2LY5 A;  1PTX A;  2N2Q A;  1XRS B;  3LDL A;  2E8A A;  1NH5 A;  3D2F A;  2QWR A;  5BPL A;  2B68 A;  4AB0 A;  5AQY A;  1OZZ A;  1ZVG A;  5BN9 A;  2BRZ A;  2LT8 A;  1L4V A;  1AHO A;  4UAE F;  3D2E A;  1ZFU A;  2A7T A;  1KV0 A;  1ZU3 A;  1BMR A;  3QML A;  1N4N A;  1JZA A;  4HE7 A;  2NY9 X;  5EXW A;  5F2R A;  2M8B B;  2KBJ A;  3KP0 A;  2E3G A;  1HX1 A;  2KJA A;  3A8Y A;  3D2F B;  3I33 A;  4KYP A;  2E2F A;  1PX9 A;  1QQN A;  1ATR A;  1I6F A;  1ATS A;  5AQX A;  5AQI A;  3D2E B;  2MBK A;  1BCG A;  1JXC A;  1SEG A;  3KOZ A;  1NGB A;  1YUW A;  3ATV A;  2SN3 A;  2B3C A;  5AQH A;  1VNB A;  1ZYW A;  1T7A A;  1KAY A;  2K35 A;  2MZ0 A;  3AY9 A;  3C7N A;  2QWP A;  5AQS A;  1NPI A;  2LJM A;  2ASC A;  2LY6 A;  5AQZ A;  1I2V A;  5BPN A;  1WWN A;  1NGC A;  1NRB A;  2KSK A;  2N66 A;  4H5N A;  2V7Z A;  2N2R A;  4H5T A;  1S3X A;  1BRZ A;  3KOW A;  3QFP A;  1B3C A;  4H5R A;  5AQJ A;  1CN2 A;  2YIL A;  2QWM A;  3L4I A;  3LDN A;  1NGH A;  1WMT A;  2QWO A;  5AQL A;  3LDP A;  1JZB A;  1ZVE A;  2YEO A;  1HJO A;  2BUP A;  2QW9 A;  1K8B A;  2LJ7 A;  1TI5 A;  3FE1 A;  5F0X A;  5AQP A;  3GDQ A;  1C56 A;  3GKU A;  3GL1 A;  2LI7 A;  3FZL A;  3KC6 A;  3KOY A;  1KAX A;  1UGL A;  1MR4 A;  4HHF A;  5BPM A;  2N69 A;  1FH3 A;  3ATU A;  2KGQ A;  3CW4 A;  1C55 A;  1WT7 A;  4H5W A;  3E7U X;  1NGJ A;  3PSM A;  2KYQ A;  3LDO A;  5AQG A;  4UJ0 A;  2ATB A;  1NE5 A;  1NGF A;  1POI A;  1LQH A;  1SNB A;  2YC1 C;  3CQX A;  3FZF A;  5AQW A;  5AR0 A;  5AQQ A;  2E3F A;  1BK8 A;  3FZK A;  5FPM A;  2QWQ A;  3SF4 D;  2QWL A;  1NGE A;  4GNI A;  2LR3 A;  4IO8 A;  2NY8 X;  5AQF A;  5FPN A;  5CY0 A;  1JKZ A;  1P00 A;  1QQM A;  5F1X A;  1SN1 A;  3C7N B;  4HWI A;  1P0A A;  3LDQ A;  3HSC A;  3KP1 A;  2E0H A;  2D56 A;  2LKB A;  3BK3 C;  1SN4 A;  1BA0 A;  2LN8 A;  1DKG D;  5FPD A;  4H5V A;  5BN8 A;  1CHZ A;  2E88 A;  2KBK A;  1LQQ A;  4AAZ A;  5AQK A;  5EY4 A;  1HPM A;  1GPS A;  4UAD E;  1MYN A;  1NGG A;  1T0Z A;  3QI7 A;  4KBO A;  1ICA A;  1ZUT A;  2MN5 A;  5AQN A;  1BUP A;  2KBH A;  2G2K A;  1GPT A;  2VY6 A;  1VNA A;  1OMY A;  3R2V A;  2QXL A;  5EX5 A;  5KK4 A;  2I61 A;  2GL1 A;  4UAF E;  1AYJ A;  1I2U A;  3KVG A;  1LQI A;  1DQ7 A;  1NRA A;  1NGI A;  1PE4 A;  1QQO A;  2YIP A;  3FZM A;  3IUC A;  1T1T A;  4CQK A;  5EVZ A; 
#chains in the Genus database with same CATH homology
 5AQV A;  2YIO A;  5AQU A;  3JXU A;  3M3Z A;  5AQT A;  3L56 A;  4FSV A;  2KHO A;  5AQO A;  2GMO A;  5AQM A;  3L6Q A;  2QWN A;  1BA1 A;  1KAZ A;  4FL9 A;  5FPE A;  1NGA A;  2JDQ D;  3FZH A;  3KHW A;  3QFU A;  5AQR A;  1NGD A;  3LDL A;  2E8A A;  3D2F A;  5BPL A;  2QWR A;  5AQY A;  5BN9 A;  4UAE F;  3D2E A;  3QML A;  5EXW A;  5F2R A;  1HX1 A;  3A8Y A;  3D2F B;  3I33 A;  2E2F A;  1QQN A;  1ATR A;  1ATS A;  5AQX A;  5AQI A;  3D2E B;  2MBK A;  1NGB A;  1YUW A;  3ATV A;  5AQH A;  5AQS A;  1KAY A;  2K35 A;  3AY9 A;  3C7N A;  5AQZ A;  2QWP A;  5BPN A;  1NGC A;  4H5N A;  2V7Z A;  4H5T A;  1S3X A;  3QFP A;  4H5R A;  5AQJ A;  2YIL A;  2QWM A;  3L4I A;  3LDN A;  1NGH A;  2QWO A;  5AQL A;  3LDP A;  1HJO A;  2BUP A;  2QW9 A;  3FE1 A;  5F0X A;  5AQP A;  3GDQ A;  3GL1 A;  3FZL A;  3KC6 A;  1KAX A;  5BPM A;  3ATU A;  3CW4 A;  4H5W A;  1NGJ A;  3LDO A;  5AQG A;  5AQW A;  1NGF A;  1POI A;  3CQX A;  3FZF A;  5AR0 A;  5AQQ A;  3FZK A;  5FPM A;  2QWQ A;  3SF4 D;  2QWL A;  1NGE A;  4GNI A;  4IO8 A;  5AQF A;  5FPN A;  5F1X A;  1QQM A;  3C7N B;  4HWI A;  3LDQ A;  3HSC A;  2D56 A;  3BK3 C;  1BA0 A;  2LN8 A;  1DKG D;  5FPD A;  4H5V A;  5BN8 A;  2E88 A;  5AQK A;  5EY4 A;  1HPM A;  4UAD E;  1NGG A;  3QI7 A;  4KBO A;  2MN5 A;  5AQN A;  1BUP A;  2VY6 A;  3R2V A;  2QXL A;  5EX5 A;  4UAF E;  3KVG A;  2YIP A;  3FZM A;  1QQO A;  1NGI A;  3IUC A;  5EVZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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