1T7AA

Crystal structure of mutant lys8asp of scorpion alpha-like neurotoxin bmk m1 from buthus martensii karsch
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
66
structure length
66
Chain Sequence
NSVRDAYIADPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
pubmed doi rcsb
molecule tags Toxin
source organism Mesobuthus martensii
molecule keywords Alpha-like neurotoxin BmK-I
total genus 18
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2004-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1t7aA00
4HHFA 2BRZA 1JXCA 1MYNA 1PE4A 4KYPA 2B3CA 2KBJA 1ZVGA 1NRAA 1PTXA 1MR4A 2I61A 1VNAA 1T1TA 1NH5A 2KBKA 1ZVEA 3PSMA 4AB0A 1DJTA 1AYJA 2KPYA 2KJAA 1ICAA 1B7DA 2LR3A 1JZAA 2ATBA 2E3FA 2ASCA 2N69A 1NPIA 1C56A 4AAZA 1SN4A 1OZZA 2GL1A 2KYQA 1AHOA 2LJMA 4CQKA 1ZYWA 1P00A 1PX9A 1KV0A 3E7RL 4AEIA 1SN1A 1T0ZA 1ZU3A 2NY9X 2M8BB 4HE7A 1N4NA 1T7AA 1FH3A 1BRZA 1SEGA 2SN3A 1B3CA 4V1DC 2N2RA 2KGQA 2NY8X 2E0HA 1ZFUA 2KSKA 1VNBA 1ZUTA 1JZBA 2YBRC 1DQ7A 1CHZA 1WT7A 1I2UA 1TI5A 2LKBA 1LQIA 1T7EA 1CN2A 1NE5A 2KBHA 2N66A 1L4VA 2B68A 1NRBA 2N2QA 1LQHA 2A7TA 1GPSA 2LI7A 2YEOA 2MZ0A 1I2VA 1ZYVA 1BMRA 1C55A 2LT8A 1JKZA 1SNBA 3E7UX 1OMYA 1WWNA 2YC1C 1GPTA 4UJ0A 5CY0A 1BK8A 1BCGA 2E3GA 2LY5A 1LQQA 2LJ7A 5KK4A 1I6FA 1T7BA 1I6GA 2LY6A 1P0AA 1WMTA
chains in the Genus database with same CATH superfamily
1UGLA 3KOZA 2BRZA 1JXCA 4HHFA 1MYNA 2YIOA 1PE4A 5AQVA 4KYPA 2B3CA 1QQMA 2MN5A 5AQSA 2KBJA 3KOWA 5AQXA 5AQJA 1ZVGA 2JDQD 1NRAA 1PTXA 1MR4A 2I61A 3C7NA 5AQOA 5AQNA 1VNAA 1T1TA 1NH5A 2KBKA 1ZVEA 3CW4A 1NGDA 3FZKA 3PSMA 2GMOA 2YILA 4AB0A 1DJTA 1QQOA 2LN8A 1AYJA 5AQFA 2KPYA 5FPEA 3D2EA 1HX1A 2KJAA 5BPLA 3D2FB 3L56A 3ATUA 1B7DA 2LR3A 1ICAA 5AQGA 2QWOA 1XRSB 2E2FA 1JZAA 2ATBA 2E3FA 5AQRA 4HWIA 2ASCA 2N69A 1KAXA 3FZHA 3FZFA 5BN9A 1NPIA 3GKUA 1C56A 2G2KA 4AAZA 1SN4A 2QWLA 1OZZA 4FL9A 2GL1A 1POIA 5AR0A 1NGHA 2KYQA 1AHOA 4UAFE 2LJMA 3LDOA 3LDQA 4CQKA 1DKGD 1P00A 1ZYWA 1PX9A 1BA1A 2QWNA 1KV0A 3E7RL 5AQQA 3FZLA 4AEIA 2K35A 1SN1A 1ATRA 1BA0A 1T0ZA 1ZU3A 2NY9X 3HSCA 3L4IA 1NGGA 5AQWA 1QQNA 5EY4A 1NGIA 3M3ZA 2M8BB 3KC6A 4HE7A 3SF4D 4H5NA 2VY6A 1N4NA 2QW9A 1T7AA 5AQUA 2MBKA 1BRZA 1FH3A 1ATSA 1SEGA 1NGCA 2SN3A 1NGEA 1KAYA 1YUWA 4V1DC 1B3CA 2QWRA 3KVGA 3KP0A 3KOYA 2N2RA 4UAEF 2KGQA 2NY8X 2E0HA 1ZFUA 2KSKA 1VNBA 1ZUTA 4FSVA 2V7ZA 5AQMA 4KBOA 3AY9A 2D56A 5AQZA 3IUCA 3KHWA 5FPDA 1JZBA 2YBRC 3A8YA 3KOXA 1DQ7A 1CHZA 5BN8A 1WT7A 5BPMA 1I2UA 5AQLA 1TI5A 3I33A 1NGAA 2LKBA 3C7NB 1LQIA 1T7EA 1CN2A 1KAZA 5EVZA 4H5WA 3L6QA 2E88A 1S3XA 3QI7A 5BPNA 1NE5A 3GDQA 1NGJA 2KBHA 5AQKA 2N66A 3LDLA 3ATVA 3FZMA 5F2RA 1L4VA 2QWPA 1K8BA 2B68A 3LDNA 3D2EB 1NRBA 2N2QA 1LQHA 2QXLA 2A7TA 2QWMA 3KP1A 2LI7A 2YEOA 3R2VA 1GPSA 2MZ0A 4H5RA 5EX5A 1I2VA 1NGBA 2KHOA 1ZYVA 1BMRA 2QWQA 4UADE 1HJOA 1C55A 3QFPA 2LT8A 5EXWA 5FPNA 5FPMA 1JKZA 1SNBA 4IO8A 3E7UX 3QFUA 1OMYA 1WWNA 2YC1C 1GPTA 4H5VA 4UJ0A 3GL1A 1BUPA 5CY0A 3D2FA 5AQPA 1BK8A 1BCGA 2E3GA 3BK3C 3LDPA 4H5TA 5AQTA 5F0XA 2E8AA 1LQQA 2LY5A 3FE1A 5AQHA 2LJ7A 1HPMA 5AQYA 5KK4A 1NGFA 4GNIA 1I6FA 1T7BA 1I6GA 2BUPA 2LY6A 2YIPA 3CQXA 1P0AA 1WMTA 3QMLA 5AQIA 3JXUA 5F1XA
chains in the Genus database with same CATH topology
4HHFA 2BRZA 1JXCA 1MYNA 1PE4A 4KYPA 2B3CA 2KBJA 1ZVGA 1NRAA 1PTXA 1MR4A 2I61A 1VNAA 1T1TA 1NH5A 2KBKA 1ZVEA 3PSMA 4AB0A 1DJTA 1AYJA 2KPYA 2KJAA 1ICAA 1B7DA 2LR3A 1JZAA 2ATBA 2E3FA 2ASCA 2N69A 1NPIA 1C56A 4AAZA 1SN4A 1OZZA 2GL1A 2KYQA 1AHOA 2LJMA 4CQKA 1ZYWA 1P00A 1PX9A 1KV0A 3E7RL 4AEIA 1SN1A 1T0ZA 1ZU3A 2NY9X 2M8BB 4HE7A 1N4NA 1T7AA 1FH3A 1BRZA 1SEGA 2SN3A 1B3CA 4V1DC 2N2RA 2KGQA 2NY8X 2E0HA 1ZFUA 2KSKA 1VNBA 1ZUTA 1JZBA 2YBRC 1DQ7A 1CHZA 1WT7A 1I2UA 1TI5A 2LKBA 1LQIA 1T7EA 1CN2A 1NE5A 2KBHA 2N66A 1L4VA 2B68A 1NRBA 2N2QA 1LQHA 2A7TA 1GPSA 2LI7A 2YEOA 2MZ0A 1I2VA 1ZYVA 1BMRA 1C55A 2LT8A 1JKZA 1SNBA 3E7UX 1OMYA 1WWNA 2YC1C 1GPTA 4UJ0A 5CY0A 1BK8A 1BCGA 2E3GA 2LY5A 1LQQA 2LJ7A 5KK4A 1I6FA 1T7BA 1I6GA 2LY6A 1P0AA 1WMTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HHF A;  2BRZ A;  1JXC A;  1MYN A;  1PE4 A;  4KYP A;  2B3C A;  2KBJ A;  1ZVG A;  1NRA A;  1PTX A;  1MR4 A;  2I61 A;  1VNA A;  1T1T A;  1NH5 A;  2KBK A;  1ZVE A;  3PSM A;  4AB0 A;  1DJT A;  1AYJ A;  2KPY A;  2KJA A;  1ICA A;  1B7D A;  2LR3 A;  1JZA A;  2ATB A;  2E3F A;  2ASC A;  2N69 A;  1NPI A;  1C56 A;  4AAZ A;  1SN4 A;  1OZZ A;  2GL1 A;  2KYQ A;  1AHO A;  2LJM A;  4CQK A;  1ZYW A;  1P00 A;  1PX9 A;  1KV0 A;  3E7R L;  4AEI A;  1SN1 A;  1T0Z A;  1ZU3 A;  2NY9 X;  2M8B B;  4HE7 A;  1N4N A;  1T7A A;  1FH3 A;  1BRZ A;  1SEG A;  2SN3 A;  1B3C A;  4V1D C;  2N2R A;  2KGQ A;  2NY8 X;  2E0H A;  1ZFU A;  2KSK A;  1VNB A;  1ZUT A;  1JZB A;  2YBR C;  1DQ7 A;  1CHZ A;  1WT7 A;  1I2U A;  1TI5 A;  2LKB A;  1LQI A;  1T7E A;  1CN2 A;  1NE5 A;  2KBH A;  2N66 A;  1L4V A;  2B68 A;  1NRB A;  2N2Q A;  1LQH A;  2A7T A;  1GPS A;  2LI7 A;  2YEO A;  2MZ0 A;  1I2V A;  1ZYV A;  1BMR A;  1C55 A;  2LT8 A;  1JKZ A;  1SNB A;  3E7U X;  1OMY A;  1WWN A;  2YC1 C;  1GPT A;  4UJ0 A;  5CY0 A;  1BK8 A;  1BCG A;  2E3G A;  2LY5 A;  1LQQ A;  2LJ7 A;  5KK4 A;  1I6F A;  1T7B A;  1I6G A;  2LY6 A;  1P0A A;  1WMT A; 
#chains in the Genus database with same CATH topology
 1UGL A;  3KOZ A;  2BRZ A;  1JXC A;  4HHF A;  1MYN A;  2YIO A;  1PE4 A;  5AQV A;  4KYP A;  2B3C A;  1QQM A;  2MN5 A;  5AQS A;  2KBJ A;  3KOW A;  5AQX A;  5AQJ A;  1ZVG A;  2JDQ D;  1NRA A;  1PTX A;  1MR4 A;  2I61 A;  3C7N A;  5AQO A;  5AQN A;  1VNA A;  1T1T A;  1NH5 A;  2KBK A;  1ZVE A;  3CW4 A;  1NGD A;  3FZK A;  3PSM A;  2GMO A;  2YIL A;  4AB0 A;  1DJT A;  1QQO A;  2LN8 A;  1AYJ A;  5AQF A;  2KPY A;  5FPE A;  3D2E A;  1HX1 A;  2KJA A;  5BPL A;  3D2F B;  3L56 A;  3ATU A;  1B7D A;  2LR3 A;  1ICA A;  5AQG A;  2QWO A;  1XRS B;  2E2F A;  1JZA A;  2ATB A;  2E3F A;  5AQR A;  4HWI A;  2ASC A;  2N69 A;  1KAX A;  3FZH A;  3FZF A;  5BN9 A;  1NPI A;  3GKU A;  1C56 A;  2G2K A;  4AAZ A;  1SN4 A;  2QWL A;  1OZZ A;  4FL9 A;  2GL1 A;  1POI A;  5AR0 A;  1NGH A;  2KYQ A;  1AHO A;  4UAF E;  2LJM A;  3LDO A;  3LDQ A;  4CQK A;  1DKG D;  1P00 A;  1ZYW A;  1PX9 A;  1BA1 A;  2QWN A;  1KV0 A;  3E7R L;  5AQQ A;  3FZL A;  4AEI A;  2K35 A;  1SN1 A;  1ATR A;  1BA0 A;  1T0Z A;  1ZU3 A;  2NY9 X;  3HSC A;  3L4I A;  1NGG A;  5AQW A;  1QQN A;  5EY4 A;  1NGI A;  3M3Z A;  2M8B B;  3KC6 A;  4HE7 A;  3SF4 D;  4H5N A;  2VY6 A;  1N4N A;  2QW9 A;  1T7A A;  5AQU A;  2MBK A;  1BRZ A;  1FH3 A;  1ATS A;  1SEG A;  1NGC A;  2SN3 A;  1NGE A;  1KAY A;  1YUW A;  4V1D C;  1B3C A;  2QWR A;  3KVG A;  3KP0 A;  3KOY A;  2N2R A;  4UAE F;  2KGQ A;  2NY8 X;  2E0H A;  1ZFU A;  2KSK A;  1VNB A;  1ZUT A;  4FSV A;  2V7Z A;  5AQM A;  4KBO A;  3AY9 A;  2D56 A;  5AQZ A;  3IUC A;  3KHW A;  5FPD A;  1JZB A;  2YBR C;  3A8Y A;  3KOX A;  1DQ7 A;  1CHZ A;  5BN8 A;  1WT7 A;  5BPM A;  1I2U A;  5AQL A;  1TI5 A;  3I33 A;  1NGA A;  2LKB A;  3C7N B;  1LQI A;  1T7E A;  1CN2 A;  1KAZ A;  5EVZ A;  4H5W A;  3L6Q A;  2E88 A;  1S3X A;  3QI7 A;  5BPN A;  1NE5 A;  3GDQ A;  1NGJ A;  2KBH A;  5AQK A;  2N66 A;  3LDL A;  3ATV A;  3FZM A;  5F2R A;  1L4V A;  2QWP A;  1K8B A;  2B68 A;  3LDN A;  3D2E B;  1NRB A;  2N2Q A;  1LQH A;  2QXL A;  2A7T A;  2QWM A;  3KP1 A;  2LI7 A;  2YEO A;  3R2V A;  1GPS A;  2MZ0 A;  4H5R A;  5EX5 A;  1I2V A;  1NGB A;  2KHO A;  1ZYV A;  1BMR A;  2QWQ A;  4UAD E;  1HJO A;  1C55 A;  3QFP A;  2LT8 A;  5EXW A;  5FPN A;  5FPM A;  1JKZ A;  1SNB A;  4IO8 A;  3E7U X;  3QFU A;  1OMY A;  1WWN A;  2YC1 C;  1GPT A;  4H5V A;  4UJ0 A;  3GL1 A;  1BUP A;  5CY0 A;  3D2F A;  5AQP A;  1BK8 A;  1BCG A;  2E3G A;  3BK3 C;  3LDP A;  4H5T A;  5AQT A;  5F0X A;  2E8A A;  1LQQ A;  2LY5 A;  3FE1 A;  5AQH A;  2LJ7 A;  1HPM A;  5AQY A;  5KK4 A;  1NGF A;  4GNI A;  1I6F A;  1T7B A;  1I6G A;  2BUP A;  2LY6 A;  2YIP A;  3CQX A;  1P0A A;  1WMT A;  3QML A;  5AQI A;  3JXU A;  5F1X A; 
#chains in the Genus database with same CATH homology
 4HHF A;  2BRZ A;  1JXC A;  1MYN A;  1PE4 A;  4KYP A;  2B3C A;  2KBJ A;  1ZVG A;  1NRA A;  1PTX A;  1MR4 A;  2I61 A;  1VNA A;  1T1T A;  1NH5 A;  2KBK A;  1ZVE A;  3PSM A;  4AB0 A;  1DJT A;  1AYJ A;  2KPY A;  2KJA A;  1ICA A;  1B7D A;  2LR3 A;  1JZA A;  2ATB A;  2E3F A;  2ASC A;  2N69 A;  1NPI A;  1C56 A;  4AAZ A;  1SN4 A;  1OZZ A;  2GL1 A;  2KYQ A;  1AHO A;  2LJM A;  4CQK A;  1ZYW A;  1P00 A;  1PX9 A;  1KV0 A;  3E7R L;  4AEI A;  1SN1 A;  1T0Z A;  1ZU3 A;  2NY9 X;  2M8B B;  4HE7 A;  1N4N A;  1T7A A;  1FH3 A;  1BRZ A;  1SEG A;  2SN3 A;  1B3C A;  4V1D C;  2N2R A;  2KGQ A;  2NY8 X;  2E0H A;  1ZFU A;  2KSK A;  1VNB A;  1ZUT A;  1JZB A;  2YBR C;  1DQ7 A;  1CHZ A;  1WT7 A;  1I2U A;  1TI5 A;  2LKB A;  1LQI A;  1T7E A;  1CN2 A;  1NE5 A;  2KBH A;  2N66 A;  1L4V A;  2B68 A;  1NRB A;  2N2Q A;  1LQH A;  2A7T A;  1GPS A;  2LI7 A;  2YEO A;  2MZ0 A;  1I2V A;  1ZYV A;  1BMR A;  1C55 A;  2LT8 A;  1JKZ A;  1SNB A;  3E7U X;  1OMY A;  1WWN A;  2YC1 C;  1GPT A;  4UJ0 A;  5CY0 A;  1BK8 A;  1BCG A;  2E3G A;  2LY5 A;  1LQQ A;  2LJ7 A;  5KK4 A;  1I6F A;  1T7B A;  1I6G A;  2LY6 A;  1P0A A;  1WMT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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