2NY8X

Nmr structure of antibacterial defensin def-aaa from the insect anopheles gambiae
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
40
structure length
40
Chain Sequence
ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Anopheles gambiae
molecule keywords defensin
total genus 5
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ny8X00
3PSMA 1T7EA 4UJ0A 2BRZA 1SN4A 2I61A 1T1TA 2KGQA 1L4VA 4AEIA 1BK8A 2LY6A 2LJ7A 2E3GA 1SNBA 1ZVEA 3E7RL 1T7BA 1AYJA 2LT8A 4CQKA 1LQQA 4AAZA 2LY5A 1AHOA 2LJMA 1DJTA 1P0AA 1C56A 1JZAA 1TI5A 2KSKA 1NE5A 4HHFA 1WT7A 3E7UX 1I6GA 1KV0A 1VNBA 1N4NA 1PE4A 2LI7A 2N2RA 1BRZA 1JKZA 1B3CA 1MYNA 2LR3A 1NRBA 2YBRC 4HE7A 2ASCA 2MZ0A 1SEGA 1ZYVA 1SN1A 1ZUTA 1T7AA 2N66A 1DQ7A 1PTXA 2KPYA 1T0ZA 4KYPA 1LQIA 1PX9A 1I2VA 2KBKA 1JXCA 2KJAA 5KK4A 2B68A 2LKBA 1ZVGA 1ZFUA 1WWNA 2YC1C 1WMTA 2KBHA 1LQHA 2N2QA 2ATBA 1I6FA 1JZBA 2A7TA 2E3FA 1OMYA 1P00A 2B3CA 1CHZA 2NY9X 1CN2A 2M8BB 1NH5A 1FH3A 5CY0A 1GPSA 1NPIA 2GL1A 1BMRA 1B7DA 2KBJA 1MR4A 1NRAA 2NY8X 2YEOA 2E0HA 1GPTA 2SN3A 4V1DC 1ICAA 2N69A 1C55A 1BCGA 1ZYWA 1ZU3A 1OZZA 2KYQA 1I2UA 4AB0A 1VNAA
chains in the Genus database with same CATH superfamily
2YIOA 3PSMA 1T7EA 5AQIA 2BRZA 1SN4A 4UJ0A 2I61A 2QWRA 1T1TA 2KGQA 1QQMA 1L4VA 5FPNA 3FE1A 4AEIA 3HSCA 5AR0A 5AQYA 3QI7A 5EY4A 3ATUA 1BK8A 2LY6A 1NGAA 2LJ7A 2E3GA 2KHOA 1SNBA 1ZVEA 2GMOA 2QWNA 1NGJA 4KBOA 3E7RL 3KOZA 1T7BA 1NGCA 1AYJA 5AQPA 2LT8A 1BA1A 4CQKA 3D2FA 2QWLA 2K35A 2QXLA 4UADE 5AQMA 1LQQA 4UAFE 5AQKA 3LDNA 2LY5A 3KVGA 3C7NA 1BA0A 3I33A 2LN8A 1AHOA 4AAZA 3KOYA 2LJMA 2V7ZA 1QQNA 5AQOA 4H5TA 1DJTA 1P0AA 2JDQD 1C56A 1HPMA 1JZAA 1TI5A 2KSKA 3R2VA 3LDPA 1UGLA 1NE5A 4HHFA 3CW4A 3CQXA 3IUCA 1WT7A 5AQXA 2E8AA 3ATVA 3E7UX 5AQLA 1I6GA 1KV0A 1VNBA 1N4NA 1PE4A 3D2FB 1NGBA 2LI7A 2N2RA 5EXWA 1BRZA 1JKZA 1B3CA 1BUPA 5BPMA 1MYNA 2LR3A 1NGDA 3C7NB 1NRBA 1KAZA 2QWQA 2VY6A 2YBRC 4H5VA 3LDQA 5EX5A 5FPDA 3L56A 4HE7A 2ASCA 2MZ0A 1SEGA 3L4IA 2YILA 3FZLA 3A8YA 1ZYVA 1SN1A 2MN5A 1ZUTA 2QWMA 5AQTA 3GKUA 3FZMA 5BPLA 1T7AA 4FSVA 5AQWA 5AQQA 1HX1A 5FPEA 2QW9A 2N66A 3KOWA 3KP0A 1DQ7A 3BK3C 1PTXA 2E88A 2KPYA 1T0ZA 4KYPA 1LQIA 5AQFA 1PX9A 5F2RA 1YUWA 1I2VA 1POIA 2KBKA 1NGIA 1JXCA 1XRSB 2KJAA 5AQVA 2B68A 5KK4A 2LKBA 1ZVGA 1ATRA 3GL1A 3QFUA 4H5WA 1ZFUA 1KAXA 1WWNA 5F1XA 2YC1C 2G2KA 2MBKA 5AQJA 1NGFA 1WMTA 2KBHA 4H5NA 1LQHA 2N2QA 2ATBA 2YIPA 1I6FA 3KC6A 4UAEF 5AQUA 1JZBA 2A7TA 2E3FA 5AQNA 1ATSA 4IO8A 5FPMA 5AQSA 1OMYA 3LDLA 1S3XA 2E2FA 3FZHA 3D2EA 1P00A 3FZFA 3QMLA 2B3CA 5AQHA 5EVZA 1CHZA 2NY9X 3M3ZA 1CN2A 1HJOA 2M8BB 2QWOA 1NGHA 1NH5A 3GDQA 1DKGD 3KP1A 4HWIA 5CY0A 1KAYA 1FH3A 1GPSA 1K8BA 1NPIA 2GL1A 5F0XA 1NGGA 1BMRA 1B7DA 1NGEA 2KBJA 1MR4A 5BN8A 3AY9A 1NRAA 2NY8X 2YEOA 2E0HA 2D56A 3KHWA 5AQGA 2QWPA 2SN3A 1GPTA 4V1DC 4FL9A 3QFPA 2BUPA 3SF4D 5AQZA 1ICAA 3FZKA 4H5RA 5BPNA 2N69A 5BN9A 3JXUA 1C55A 5AQRA 1BCGA 3D2EB 3L6QA 3LDOA 1ZYWA 1QQOA 1OZZA 1ZU3A 2KYQA 3KOXA 1I2UA 4AB0A 4GNIA 1VNAA
chains in the Genus database with same CATH topology
3PSMA 1T7EA 4UJ0A 2BRZA 1SN4A 2I61A 1T1TA 2KGQA 1L4VA 4AEIA 1BK8A 2LY6A 2LJ7A 2E3GA 1SNBA 1ZVEA 3E7RL 1T7BA 1AYJA 2LT8A 4CQKA 1LQQA 4AAZA 2LY5A 1AHOA 2LJMA 1DJTA 1P0AA 1C56A 1JZAA 1TI5A 2KSKA 1NE5A 4HHFA 1WT7A 3E7UX 1I6GA 1KV0A 1VNBA 1N4NA 1PE4A 2LI7A 2N2RA 1BRZA 1JKZA 1B3CA 1MYNA 2LR3A 1NRBA 2YBRC 4HE7A 2ASCA 2MZ0A 1SEGA 1ZYVA 1SN1A 1ZUTA 1T7AA 2N66A 1DQ7A 1PTXA 2KPYA 1T0ZA 4KYPA 1LQIA 1PX9A 1I2VA 2KBKA 1JXCA 2KJAA 5KK4A 2B68A 2LKBA 1ZVGA 1ZFUA 1WWNA 2YC1C 1WMTA 2KBHA 1LQHA 2N2QA 2ATBA 1I6FA 1JZBA 2A7TA 2E3FA 1OMYA 1P00A 2B3CA 1CHZA 2NY9X 1CN2A 2M8BB 1NH5A 1FH3A 5CY0A 1GPSA 1NPIA 2GL1A 1BMRA 1B7DA 2KBJA 1MR4A 1NRAA 2NY8X 2YEOA 2E0HA 1GPTA 2SN3A 4V1DC 1ICAA 2N69A 1C55A 1BCGA 1ZYWA 1ZU3A 1OZZA 2KYQA 1I2UA 4AB0A 1VNAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PSM A;  1T7E A;  4UJ0 A;  2BRZ A;  1SN4 A;  2I61 A;  1T1T A;  2KGQ A;  1L4V A;  4AEI A;  1BK8 A;  2LY6 A;  2LJ7 A;  2E3G A;  1SNB A;  1ZVE A;  3E7R L;  1T7B A;  1AYJ A;  2LT8 A;  4CQK A;  1LQQ A;  4AAZ A;  2LY5 A;  1AHO A;  2LJM A;  1DJT A;  1P0A A;  1C56 A;  1JZA A;  1TI5 A;  2KSK A;  1NE5 A;  4HHF A;  1WT7 A;  3E7U X;  1I6G A;  1KV0 A;  1VNB A;  1N4N A;  1PE4 A;  2LI7 A;  2N2R A;  1BRZ A;  1JKZ A;  1B3C A;  1MYN A;  2LR3 A;  1NRB A;  2YBR C;  4HE7 A;  2ASC A;  2MZ0 A;  1SEG A;  1ZYV A;  1SN1 A;  1ZUT A;  1T7A A;  2N66 A;  1DQ7 A;  1PTX A;  2KPY A;  1T0Z A;  4KYP A;  1LQI A;  1PX9 A;  1I2V A;  2KBK A;  1JXC A;  2KJA A;  5KK4 A;  2B68 A;  2LKB A;  1ZVG A;  1ZFU A;  1WWN A;  2YC1 C;  1WMT A;  2KBH A;  1LQH A;  2N2Q A;  2ATB A;  1I6F A;  1JZB A;  2A7T A;  2E3F A;  1OMY A;  1P00 A;  2B3C A;  1CHZ A;  2NY9 X;  1CN2 A;  2M8B B;  1NH5 A;  1FH3 A;  5CY0 A;  1GPS A;  1NPI A;  2GL1 A;  1BMR A;  1B7D A;  2KBJ A;  1MR4 A;  1NRA A;  2NY8 X;  2YEO A;  2E0H A;  1GPT A;  2SN3 A;  4V1D C;  1ICA A;  2N69 A;  1C55 A;  1BCG A;  1ZYW A;  1ZU3 A;  1OZZ A;  2KYQ A;  1I2U A;  4AB0 A;  1VNA A; 
#chains in the Genus database with same CATH topology
 2YIO A;  3PSM A;  1T7E A;  5AQI A;  2BRZ A;  1SN4 A;  4UJ0 A;  2I61 A;  2QWR A;  1T1T A;  2KGQ A;  1QQM A;  1L4V A;  5FPN A;  3FE1 A;  4AEI A;  3HSC A;  5AR0 A;  5AQY A;  3QI7 A;  5EY4 A;  3ATU A;  1BK8 A;  2LY6 A;  1NGA A;  2LJ7 A;  2E3G A;  2KHO A;  1SNB A;  1ZVE A;  2GMO A;  2QWN A;  1NGJ A;  4KBO A;  3E7R L;  3KOZ A;  1T7B A;  1NGC A;  1AYJ A;  5AQP A;  2LT8 A;  1BA1 A;  4CQK A;  3D2F A;  2QWL A;  2K35 A;  2QXL A;  4UAD E;  5AQM A;  1LQQ A;  4UAF E;  5AQK A;  3LDN A;  2LY5 A;  3KVG A;  3C7N A;  1BA0 A;  3I33 A;  2LN8 A;  1AHO A;  4AAZ A;  3KOY A;  2LJM A;  2V7Z A;  1QQN A;  5AQO A;  4H5T A;  1DJT A;  1P0A A;  2JDQ D;  1C56 A;  1HPM A;  1JZA A;  1TI5 A;  2KSK A;  3R2V A;  3LDP A;  1UGL A;  1NE5 A;  4HHF A;  3CW4 A;  3CQX A;  3IUC A;  1WT7 A;  5AQX A;  2E8A A;  3ATV A;  3E7U X;  5AQL A;  1I6G A;  1KV0 A;  1VNB A;  1N4N A;  1PE4 A;  3D2F B;  1NGB A;  2LI7 A;  2N2R A;  5EXW A;  1BRZ A;  1JKZ A;  1B3C A;  1BUP A;  5BPM A;  1MYN A;  2LR3 A;  1NGD A;  3C7N B;  1NRB A;  1KAZ A;  2QWQ A;  2VY6 A;  2YBR C;  4H5V A;  3LDQ A;  5EX5 A;  5FPD A;  3L56 A;  4HE7 A;  2ASC A;  2MZ0 A;  1SEG A;  3L4I A;  2YIL A;  3FZL A;  3A8Y A;  1ZYV A;  1SN1 A;  2MN5 A;  1ZUT A;  2QWM A;  5AQT A;  3GKU A;  3FZM A;  5BPL A;  1T7A A;  4FSV A;  5AQW A;  5AQQ A;  1HX1 A;  5FPE A;  2QW9 A;  2N66 A;  3KOW A;  3KP0 A;  1DQ7 A;  3BK3 C;  1PTX A;  2E88 A;  2KPY A;  1T0Z A;  4KYP A;  1LQI A;  5AQF A;  1PX9 A;  5F2R A;  1YUW A;  1I2V A;  1POI A;  2KBK A;  1NGI A;  1JXC A;  1XRS B;  2KJA A;  5AQV A;  2B68 A;  5KK4 A;  2LKB A;  1ZVG A;  1ATR A;  3GL1 A;  3QFU A;  4H5W A;  1ZFU A;  1KAX A;  1WWN A;  5F1X A;  2YC1 C;  2G2K A;  2MBK A;  5AQJ A;  1NGF A;  1WMT A;  2KBH A;  4H5N A;  1LQH A;  2N2Q A;  2ATB A;  2YIP A;  1I6F A;  3KC6 A;  4UAE F;  5AQU A;  1JZB A;  2A7T A;  2E3F A;  5AQN A;  1ATS A;  4IO8 A;  5FPM A;  5AQS A;  1OMY A;  3LDL A;  1S3X A;  2E2F A;  3FZH A;  3D2E A;  1P00 A;  3FZF A;  3QML A;  2B3C A;  5AQH A;  5EVZ A;  1CHZ A;  2NY9 X;  3M3Z A;  1CN2 A;  1HJO A;  2M8B B;  2QWO A;  1NGH A;  1NH5 A;  3GDQ A;  1DKG D;  3KP1 A;  4HWI A;  5CY0 A;  1KAY A;  1FH3 A;  1GPS A;  1K8B A;  1NPI A;  2GL1 A;  5F0X A;  1NGG A;  1BMR A;  1B7D A;  1NGE A;  2KBJ A;  1MR4 A;  5BN8 A;  3AY9 A;  1NRA A;  2NY8 X;  2YEO A;  2E0H A;  2D56 A;  3KHW A;  5AQG A;  2QWP A;  2SN3 A;  1GPT A;  4V1D C;  4FL9 A;  3QFP A;  2BUP A;  3SF4 D;  5AQZ A;  1ICA A;  3FZK A;  4H5R A;  5BPN A;  2N69 A;  5BN9 A;  3JXU A;  1C55 A;  5AQR A;  1BCG A;  3D2E B;  3L6Q A;  3LDO A;  1ZYW A;  1QQO A;  1OZZ A;  1ZU3 A;  2KYQ A;  3KOX A;  1I2U A;  4AB0 A;  4GNI A;  1VNA A; 
#chains in the Genus database with same CATH homology
 3PSM A;  1T7E A;  4UJ0 A;  2BRZ A;  1SN4 A;  2I61 A;  1T1T A;  2KGQ A;  1L4V A;  4AEI A;  1BK8 A;  2LY6 A;  2LJ7 A;  2E3G A;  1SNB A;  1ZVE A;  3E7R L;  1T7B A;  1AYJ A;  2LT8 A;  4CQK A;  1LQQ A;  4AAZ A;  2LY5 A;  1AHO A;  2LJM A;  1DJT A;  1P0A A;  1C56 A;  1JZA A;  1TI5 A;  2KSK A;  1NE5 A;  4HHF A;  1WT7 A;  3E7U X;  1I6G A;  1KV0 A;  1VNB A;  1N4N A;  1PE4 A;  2LI7 A;  2N2R A;  1BRZ A;  1JKZ A;  1B3C A;  1MYN A;  2LR3 A;  1NRB A;  2YBR C;  4HE7 A;  2ASC A;  2MZ0 A;  1SEG A;  1ZYV A;  1SN1 A;  1ZUT A;  1T7A A;  2N66 A;  1DQ7 A;  1PTX A;  2KPY A;  1T0Z A;  4KYP A;  1LQI A;  1PX9 A;  1I2V A;  2KBK A;  1JXC A;  2KJA A;  5KK4 A;  2B68 A;  2LKB A;  1ZVG A;  1ZFU A;  1WWN A;  2YC1 C;  1WMT A;  2KBH A;  1LQH A;  2N2Q A;  2ATB A;  1I6F A;  1JZB A;  2A7T A;  2E3F A;  1OMY A;  1P00 A;  2B3C A;  1CHZ A;  2NY9 X;  1CN2 A;  2M8B B;  1NH5 A;  1FH3 A;  5CY0 A;  1GPS A;  1NPI A;  2GL1 A;  1BMR A;  1B7D A;  2KBJ A;  1MR4 A;  1NRA A;  2NY8 X;  2YEO A;  2E0H A;  1GPT A;  2SN3 A;  4V1D C;  1ICA A;  2N69 A;  1C55 A;  1BCG A;  1ZYW A;  1ZU3 A;  1OZZ A;  2KYQ A;  1I2U A;  4AB0 A;  1VNA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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