2NY8X

Nmr structure of antibacterial defensin def-aaa from the insect anopheles gambiae
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
40
structure length
40
Chain Sequence
ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords defensin
publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
source organism Anopheles gambiae
molecule tags Antimicrobial protein
total genus 5
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ny8X00
1TI5A 3E7RL 1AYJA 1JZBA 1NRAA 1BMRA 1VNAA 2KPYA 2A7TA 2LI7A 1GPTA 2MZ0A 5KK4A 1T0ZA 1T7BA 2YEOA 2YBRC 1ZVGA 1FH3A 3E7UX 2E0HA 1ZVEA 1B3CA 2B68A 2NY9X 2E3GA 1JXCA 1JKZA 1L4VA 2B3CA 1N4NA 1MYNA 1SN4A 2NY8X 1C55A 4V1DC 1PTXA 2KJAA 1I6FA 1T7EA 4HHFA 2SN3A 2N2RA 2ASCA 2KSKA 2KBHA 3PSMA 2LKBA 2KYQA 4CQKA 1ZYVA 2LY5A 1WT7A 1MR4A 1JZAA 2LJ7A 1NH5A 1ZUTA 4HE7A 1BCGA 1CHZA 1LQIA 2GL1A 1PX9A 2M8BB 2N66A 1I2VA 1P00A 1OZZA 1ZFUA 1NRBA 1ICAA 1C56A 1SN1A 4UJ0A 4AEIA 2N2QA 1T7AA 1B7DA 2N69A 1WWNA 1VNBA 1I6GA 1BRZA 2LY6A 1LQHA 1NPIA 2ATBA 1LQQA 1ZU3A 1DJTA 1SEGA 1OMYA 2LJMA 5CY0A 1I2UA 1DQ7A 2I61A 2KBJA 2YC1C 4AB0A 4AAZA 1AHOA 1KV0A 1WMTA 1CN2A 1ZYWA 2LR3A 2E3FA 1P0AA 1GPSA 2LT8A 1PE4A 1NE5A 2KGQA 2BRZA 4KYPA 1BK8A 2KBKA 1T1TA 1SNBA
chains in the Genus database with same CATH superfamily
1TI5A 3E7RL 3JXUA 1JZBA 3L6QA 1NRAA 4HWIA 1BMRA 1HPMA 1AYJA 1VNAA 3GL1A 2KPYA 3I33A 2A7TA 3KOWA 1BA1A 2LI7A 3KHWA 1GPTA 3L4IA 2MZ0A 3M3ZA 4FSVA 5KK4A 1T0ZA 1T7BA 2YEOA 2YBRC 1ATRA 1ZVGA 4IO8A 1FH3A 4UAEF 5AQWA 3E7UX 2E0HA 2QWMA 2G2KA 1ZVEA 1B3CA 2B68A 1KAZA 5FPEA 2NY9X 2E3GA 1JXCA 1JKZA 1L4VA 2B3CA 1N4NA 1MYNA 1SN4A 5EY4A 1I6GA 1QQNA 2D56A 2NY8X 1C55A 2QWPA 5AQJA 2E88A 4V1DC 5AQZA 1PTXA 2KJAA 1BA0A 3LDPA 5AQQA 1I6FA 5AQTA 5F1XA 1T7EA 4HHFA 2YIOA 2K35A 2YIPA 2SN3A 1S3XA 2N2RA 5BN9A 2ASCA 2KSKA 2VY6A 5AQRA 3GKUA 2KBHA 1ATSA 2QWNA 1NGHA 3CW4A 3C7NB 3LDOA 3PSMA 2LKBA 2KYQA 4CQKA 1ZYVA 2LY5A 1WT7A 3GDQA 1MR4A 1BUPA 1JZAA 3FZHA 2LJ7A 1NH5A 3ATUA 1QQOA 1YUWA 1ZUTA 3D2EB 3KP0A 4HE7A 4H5WA 1BCGA 2MBKA 5AQNA 1CHZA 1NGGA 3FZLA 4H5RA 4UADE 3D2FB 5AQPA 1LQIA 3LDNA 5BPMA 2GL1A 1PX9A 2M8BB 2N66A 1I2VA 1P00A 1OZZA 3LDLA 5AQGA 1ZFUA 2GMOA 1NRBA 2YILA 1ICAA 1C56A 1SN1A 5AQKA 4UJ0A 4AEIA 2N2QA 1T7AA 3A8YA 3CQXA 1B7DA 1HX1A 2KHOA 2QWOA 3BK3C 3FZMA 4UAFE 2N69A 5BPLA 1WWNA 1VNBA 1KAYA 3QFPA 2LN8A 4H5VA 1BRZA 2LY6A 1LQHA 1NGBA 5EVZA 1NPIA 2ATBA 1LQQA 2MN5A 3QMLA 1ZU3A 5AQLA 1DJTA 1SEGA 3ATVA 4KBOA 3QI7A 1NGIA 1NGEA 1XRSB 3IUCA 3KOYA 5AQHA 1OMYA 2LJMA 5CY0A 1I2UA 2QXLA 3SF4D 5F0XA 1DKGD 2QW9A 1NGCA 1NGJA 1UGLA 1QQMA 1NGAA 5AQUA 1DQ7A 2QWRA 2I61A 5AQSA 2KBJA 2YC1C 5AQFA 3C7NA 5AQYA 3FZKA 4AB0A 4AAZA 5EXWA 2QWLA 4H5NA 1AHOA 1KV0A 2E8AA 1WMTA 2BUPA 3KP1A 1ZYWA 4FL9A 5AQOA 5AQVA 5EX5A 2LR3A 1CN2A 4GNIA 2E3FA 3D2EA 5FPNA 3KOXA 3LDQA 1K8BA 5AR0A 1P0AA 2QWQA 1GPSA 3HSCA 5AQXA 2LT8A 2V7ZA 3D2FA 5AQMA 1KAXA 1NGFA 3AY9A 1PE4A 1HJOA 1NE5A 3R2VA 4H5TA 2KGQA 3L56A 2BRZA 5AQIA 5BN8A 4KYPA 1NGDA 1BK8A 1POIA 3FE1A 2KBKA 2E2FA 3QFUA 5FPDA 3KVGA 5F2RA 5FPMA 2JDQD 1T1TA 3FZFA 1SNBA 3KOZA 5BPNA 3KC6A
chains in the Genus database with same CATH topology
1TI5A 3E7RL 1AYJA 1JZBA 1NRAA 1BMRA 1VNAA 2KPYA 2A7TA 2LI7A 1GPTA 2MZ0A 5KK4A 1T0ZA 1T7BA 2YEOA 2YBRC 1ZVGA 1FH3A 3E7UX 2E0HA 1ZVEA 1B3CA 2B68A 2NY9X 2E3GA 1JXCA 1JKZA 1L4VA 2B3CA 1N4NA 1MYNA 1SN4A 2NY8X 1C55A 4V1DC 1PTXA 2KJAA 1I6FA 1T7EA 4HHFA 2SN3A 2N2RA 2ASCA 2KSKA 2KBHA 3PSMA 2LKBA 2KYQA 4CQKA 1ZYVA 2LY5A 1WT7A 1MR4A 1JZAA 2LJ7A 1NH5A 1ZUTA 4HE7A 1BCGA 1CHZA 1LQIA 2GL1A 1PX9A 2M8BB 2N66A 1I2VA 1P00A 1OZZA 1ZFUA 1NRBA 1ICAA 1C56A 1SN1A 4UJ0A 4AEIA 2N2QA 1T7AA 1B7DA 2N69A 1WWNA 1VNBA 1I6GA 1BRZA 2LY6A 1LQHA 1NPIA 2ATBA 1LQQA 1ZU3A 1DJTA 1SEGA 1OMYA 2LJMA 5CY0A 1I2UA 1DQ7A 2I61A 2KBJA 2YC1C 4AB0A 4AAZA 1AHOA 1KV0A 1WMTA 1CN2A 1ZYWA 2LR3A 2E3FA 1P0AA 1GPSA 2LT8A 1PE4A 1NE5A 2KGQA 2BRZA 4KYPA 1BK8A 2KBKA 1T1TA 1SNBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TI5 A;  3E7R L;  1AYJ A;  1JZB A;  1NRA A;  1BMR A;  1VNA A;  2KPY A;  2A7T A;  2LI7 A;  1GPT A;  2MZ0 A;  5KK4 A;  1T0Z A;  1T7B A;  2YEO A;  2YBR C;  1ZVG A;  1FH3 A;  3E7U X;  2E0H A;  1ZVE A;  1B3C A;  2B68 A;  2NY9 X;  2E3G A;  1JXC A;  1JKZ A;  1L4V A;  2B3C A;  1N4N A;  1MYN A;  1SN4 A;  2NY8 X;  1C55 A;  4V1D C;  1PTX A;  2KJA A;  1I6F A;  1T7E A;  4HHF A;  2SN3 A;  2N2R A;  2ASC A;  2KSK A;  2KBH A;  3PSM A;  2LKB A;  2KYQ A;  4CQK A;  1ZYV A;  2LY5 A;  1WT7 A;  1MR4 A;  1JZA A;  2LJ7 A;  1NH5 A;  1ZUT A;  4HE7 A;  1BCG A;  1CHZ A;  1LQI A;  2GL1 A;  1PX9 A;  2M8B B;  2N66 A;  1I2V A;  1P00 A;  1OZZ A;  1ZFU A;  1NRB A;  1ICA A;  1C56 A;  1SN1 A;  4UJ0 A;  4AEI A;  2N2Q A;  1T7A A;  1B7D A;  2N69 A;  1WWN A;  1VNB A;  1I6G A;  1BRZ A;  2LY6 A;  1LQH A;  1NPI A;  2ATB A;  1LQQ A;  1ZU3 A;  1DJT A;  1SEG A;  1OMY A;  2LJM A;  5CY0 A;  1I2U A;  1DQ7 A;  2I61 A;  2KBJ A;  2YC1 C;  4AB0 A;  4AAZ A;  1AHO A;  1KV0 A;  1WMT A;  1CN2 A;  1ZYW A;  2LR3 A;  2E3F A;  1P0A A;  1GPS A;  2LT8 A;  1PE4 A;  1NE5 A;  2KGQ A;  2BRZ A;  4KYP A;  1BK8 A;  2KBK A;  1T1T A;  1SNB A; 
#chains in the Genus database with same CATH topology
 1TI5 A;  3E7R L;  3JXU A;  1JZB A;  3L6Q A;  1NRA A;  4HWI A;  1BMR A;  1HPM A;  1AYJ A;  1VNA A;  3GL1 A;  2KPY A;  3I33 A;  2A7T A;  3KOW A;  1BA1 A;  2LI7 A;  3KHW A;  1GPT A;  3L4I A;  2MZ0 A;  3M3Z A;  4FSV A;  5KK4 A;  1T0Z A;  1T7B A;  2YEO A;  2YBR C;  1ATR A;  1ZVG A;  4IO8 A;  1FH3 A;  4UAE F;  5AQW A;  3E7U X;  2E0H A;  2QWM A;  2G2K A;  1ZVE A;  1B3C A;  2B68 A;  1KAZ A;  5FPE A;  2NY9 X;  2E3G A;  1JXC A;  1JKZ A;  1L4V A;  2B3C A;  1N4N A;  1MYN A;  1SN4 A;  5EY4 A;  1I6G A;  1QQN A;  2D56 A;  2NY8 X;  1C55 A;  2QWP A;  5AQJ A;  2E88 A;  4V1D C;  5AQZ A;  1PTX A;  2KJA A;  1BA0 A;  3LDP A;  5AQQ A;  1I6F A;  5AQT A;  5F1X A;  1T7E A;  4HHF A;  2YIO A;  2K35 A;  2YIP A;  2SN3 A;  1S3X A;  2N2R A;  5BN9 A;  2ASC A;  2KSK A;  2VY6 A;  5AQR A;  3GKU A;  2KBH A;  1ATS A;  2QWN A;  1NGH A;  3CW4 A;  3C7N B;  3LDO A;  3PSM A;  2LKB A;  2KYQ A;  4CQK A;  1ZYV A;  2LY5 A;  1WT7 A;  3GDQ A;  1MR4 A;  1BUP A;  1JZA A;  3FZH A;  2LJ7 A;  1NH5 A;  3ATU A;  1QQO A;  1YUW A;  1ZUT A;  3D2E B;  3KP0 A;  4HE7 A;  4H5W A;  1BCG A;  2MBK A;  5AQN A;  1CHZ A;  1NGG A;  3FZL A;  4H5R A;  4UAD E;  3D2F B;  5AQP A;  1LQI A;  3LDN A;  5BPM A;  2GL1 A;  1PX9 A;  2M8B B;  2N66 A;  1I2V A;  1P00 A;  1OZZ A;  3LDL A;  5AQG A;  1ZFU A;  2GMO A;  1NRB A;  2YIL A;  1ICA A;  1C56 A;  1SN1 A;  5AQK A;  4UJ0 A;  4AEI A;  2N2Q A;  1T7A A;  3A8Y A;  3CQX A;  1B7D A;  1HX1 A;  2KHO A;  2QWO A;  3BK3 C;  3FZM A;  4UAF E;  2N69 A;  5BPL A;  1WWN A;  1VNB A;  1KAY A;  3QFP A;  2LN8 A;  4H5V A;  1BRZ A;  2LY6 A;  1LQH A;  1NGB A;  5EVZ A;  1NPI A;  2ATB A;  1LQQ A;  2MN5 A;  3QML A;  1ZU3 A;  5AQL A;  1DJT A;  1SEG A;  3ATV A;  4KBO A;  3QI7 A;  1NGI A;  1NGE A;  1XRS B;  3IUC A;  3KOY A;  5AQH A;  1OMY A;  2LJM A;  5CY0 A;  1I2U A;  2QXL A;  3SF4 D;  5F0X A;  1DKG D;  2QW9 A;  1NGC A;  1NGJ A;  1UGL A;  1QQM A;  1NGA A;  5AQU A;  1DQ7 A;  2QWR A;  2I61 A;  5AQS A;  2KBJ A;  2YC1 C;  5AQF A;  3C7N A;  5AQY A;  3FZK A;  4AB0 A;  4AAZ A;  5EXW A;  2QWL A;  4H5N A;  1AHO A;  1KV0 A;  2E8A A;  1WMT A;  2BUP A;  3KP1 A;  1ZYW A;  4FL9 A;  5AQO A;  5AQV A;  5EX5 A;  2LR3 A;  1CN2 A;  4GNI A;  2E3F A;  3D2E A;  5FPN A;  3KOX A;  3LDQ A;  1K8B A;  5AR0 A;  1P0A A;  2QWQ A;  1GPS A;  3HSC A;  5AQX A;  2LT8 A;  2V7Z A;  3D2F A;  5AQM A;  1KAX A;  1NGF A;  3AY9 A;  1PE4 A;  1HJO A;  1NE5 A;  3R2V A;  4H5T A;  2KGQ A;  3L56 A;  2BRZ A;  5AQI A;  5BN8 A;  4KYP A;  1NGD A;  1BK8 A;  1POI A;  3FE1 A;  2KBK A;  2E2F A;  3QFU A;  5FPD A;  3KVG A;  5F2R A;  5FPM A;  2JDQ D;  1T1T A;  3FZF A;  1SNB A;  3KOZ A;  5BPN A;  3KC6 A; 
#chains in the Genus database with same CATH homology
 1TI5 A;  3E7R L;  1AYJ A;  1JZB A;  1NRA A;  1BMR A;  1VNA A;  2KPY A;  2A7T A;  2LI7 A;  1GPT A;  2MZ0 A;  5KK4 A;  1T0Z A;  1T7B A;  2YEO A;  2YBR C;  1ZVG A;  1FH3 A;  3E7U X;  2E0H A;  1ZVE A;  1B3C A;  2B68 A;  2NY9 X;  2E3G A;  1JXC A;  1JKZ A;  1L4V A;  2B3C A;  1N4N A;  1MYN A;  1SN4 A;  2NY8 X;  1C55 A;  4V1D C;  1PTX A;  2KJA A;  1I6F A;  1T7E A;  4HHF A;  2SN3 A;  2N2R A;  2ASC A;  2KSK A;  2KBH A;  3PSM A;  2LKB A;  2KYQ A;  4CQK A;  1ZYV A;  2LY5 A;  1WT7 A;  1MR4 A;  1JZA A;  2LJ7 A;  1NH5 A;  1ZUT A;  4HE7 A;  1BCG A;  1CHZ A;  1LQI A;  2GL1 A;  1PX9 A;  2M8B B;  2N66 A;  1I2V A;  1P00 A;  1OZZ A;  1ZFU A;  1NRB A;  1ICA A;  1C56 A;  1SN1 A;  4UJ0 A;  4AEI A;  2N2Q A;  1T7A A;  1B7D A;  2N69 A;  1WWN A;  1VNB A;  1I6G A;  1BRZ A;  2LY6 A;  1LQH A;  1NPI A;  2ATB A;  1LQQ A;  1ZU3 A;  1DJT A;  1SEG A;  1OMY A;  2LJM A;  5CY0 A;  1I2U A;  1DQ7 A;  2I61 A;  2KBJ A;  2YC1 C;  4AB0 A;  4AAZ A;  1AHO A;  1KV0 A;  1WMT A;  1CN2 A;  1ZYW A;  2LR3 A;  2E3F A;  1P0A A;  1GPS A;  2LT8 A;  1PE4 A;  1NE5 A;  2KGQ A;  2BRZ A;  4KYP A;  1BK8 A;  2KBK A;  1T1T A;  1SNB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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